-
1
-
-
0028172089
-
Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis
-
Ashby, J., Brady, A., Elcombe, C. R., Elliott, B. M., Ishamael, J., Odum, J., Tugwood, J. D., Kettle, S., and Purchase, L. F. H. (1994). Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum. Exp. Toxicol. 13(Suppl. 2), S1-S117.
-
(1994)
Hum. Exp. Toxicol.
, vol.13
, Issue.2 SUPPL.
-
-
Ashby, J.1
Brady, A.2
Elcombe, C.R.3
Elliott, B.M.4
Ishamael, J.5
Odum, J.6
Tugwood, J.D.7
Kettle, S.8
Purchase, L.F.H.9
-
2
-
-
0027161015
-
PPARRXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
-
Bardot, O., Aldridge, T. C., Latruffe, N., and Green, S. (1993). PPARRXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem. Biophys. Res. Commun. 193, 37-45.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.193
, pp. 37-45
-
-
Bardot, O.1
Aldridge, T.C.2
Latruffe, N.3
Green, S.4
-
3
-
-
0027304198
-
Comparison of the acute and chronic mitogenic effects of the peroxisome proliferator methylclofenapate and clofibric acid in rat liver
-
Barrass, N. C., Price, R. J., Lake, B. G., and Orton, T. C. (1993). Comparison of the acute and chronic mitogenic effects of the peroxisome proliferator methylclofenapate and clofibric acid in rat liver. Carcinogenesis 14(7), 1451-1456.
-
(1993)
Carcinogenesis
, vol.14
, Issue.7
, pp. 1451-1456
-
-
Barrass, N.C.1
Price, R.J.2
Lake, B.G.3
Orton, T.C.4
-
4
-
-
0027763648
-
Hepatic peroxisome proliferation in rodents and its significance for humans
-
Bentley, P., Calder, I., Elcombe, C., Grasso, P., Stringer, D., and Wiegand, H. J. (1993). Hepatic peroxisome proliferation in rodents and its significance for humans. Food Chem. Toxicol. 31, 857-907.
-
(1993)
Food Chem. Toxicol.
, vol.31
, pp. 857-907
-
-
Bentley, P.1
Calder, I.2
Elcombe, C.3
Grasso, P.4
Stringer, D.5
Wiegand, H.J.6
-
5
-
-
0029112633
-
Effects of ammonium perfluorooctanoate on leydig cell function: In vitro, in vivo, and ex vivo studies
-
Biegel, L. B., Liu, R. C. M., Hurt, M. E., and Cook, J. C. (1995). Effects of ammonium perfluorooctanoate on leydig cell function: In vitro, in vivo, and ex vivo studies. Toxicol. Appl. Pharmacol. 134(1), 18-25.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.134
, Issue.1
, pp. 18-25
-
-
Biegel, L.B.1
Liu, R.C.M.2
Hurt, M.E.3
Cook, J.C.4
-
6
-
-
0020686679
-
Influence of fenofibrate on cellular and subcellular liver structure in hyperlipidemic patients
-
Blumcke, S., Schwartzkopff, W., Lobeck, H., Edmondson, N. A., Prentice, D. E., and Blane, G. F. (1983). Influence of fenofibrate on cellular and subcellular liver structure in hyperlipidemic patients. Atherosclerosis 46, 105-116.
-
(1983)
Atherosclerosis
, vol.46
, pp. 105-116
-
-
Blumcke, S.1
Schwartzkopff, W.2
Lobeck, H.3
Edmondson, N.A.4
Prentice, D.E.5
Blane, G.F.6
-
7
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARS) - Tissue distribution of PPAR-α, -β, and -γ in the adult rat
-
Braissant, O., Foufelle, F., Scotto, D., Dauca, M., and Wahli, W. (1996). Differential expression of peroxisome proliferator-activated receptors (PPARS) - Tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 137, 334-366.
-
(1996)
Endocrinology
, vol.137
, pp. 334-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, D.3
Dauca, M.4
Wahli, W.5
-
8
-
-
33847438172
-
Toxicokinetics of gemfibrozil in rats, mice and hamsters
-
Buchanan, J. R., Grizzle, T. B., Buckley Kedderis, L., Collins, B. J., Goehl, T. J., Handy, R. W., and Marsman, D. S. (1995). Toxicokinetics of gemfibrozil in rats, mice and hamsters. Int. Toxicologist VII, 47 P-14.
-
(1995)
Int. Toxicologist
, vol.7
, pp. 47
-
-
Buchanan, J.R.1
Grizzle, T.B.2
Buckley Kedderis, L.3
Collins, B.J.4
Goehl, T.J.5
Handy, R.W.6
Marsman, D.S.7
-
9
-
-
0021248961
-
Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters
-
Bursch, W., Lauer, B., Timmermann-Trosiener, L, Barthel, G., Schuppler, J., and Schulte-Hermann, R. (1984). Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 5(4), 453-458.
-
(1984)
Carcinogenesis
, vol.5
, Issue.4
, pp. 453-458
-
-
Bursch, W.1
Lauer, B.2
Timmermann-Trosiener, L.3
Barthel, G.4
Schuppler, J.5
Schulte-Hermann, R.6
-
10
-
-
0027732501
-
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferator-relationship to carcinogenesis and nuclear localization
-
Cattley, R. C., and Glover, S. E. (1993). Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferator-relationship to carcinogenesis and nuclear localization. Carcinogenesis 14(12), 2495-2499.
-
(1993)
Carcinogenesis
, vol.14
, Issue.12
, pp. 2495-2499
-
-
Cattley, R.C.1
Glover, S.E.2
-
11
-
-
0024314929
-
Differences in the promoting activities of the peroxisome proliferator Wy-14,643 and phenobarbital in rat liver
-
Cattley, R. C., and Popp, J. A. (1989). Differences in the promoting activities of the peroxisome proliferator Wy-14,643 and phenobarbital in rat liver. Cancer Res. 49, 3246-3251.
-
(1989)
Cancer Res.
, vol.49
, pp. 3246-3251
-
-
Cattley, R.C.1
Popp, J.A.2
-
12
-
-
0025832995
-
Age-related susceptibility to the carcinogenic effect of the peroxisome proliferation Wy-14,643 in rat liver
-
Cattley, R. C., Marsman, D. S., and Popp, J. A. (1991). Age-related susceptibility to the carcinogenic effect of the peroxisome proliferation Wy-14,643 in rat liver. Carcinogenesis 12(3), 469-473.
-
(1991)
Carcinogenesis
, vol.12
, Issue.3
, pp. 469-473
-
-
Cattley, R.C.1
Marsman, D.S.2
Popp, J.A.3
-
13
-
-
0029148637
-
2-generation peroxisomal fatty acyl-CoA oxidase
-
2-generation peroxisomal fatty acyl-CoA oxidase. Proc. Natl. Acad. Sci. USA 92(15), 7080-7084.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, Issue.15
, pp. 7080-7084
-
-
Chu, S.1
Huang, Q.2
Alvares, K.3
Yeldandi, A.V.4
Rao, M.S.5
Reddy, J.K.6
-
14
-
-
0019824670
-
Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its lexicological significance to man
-
Cohen, A. J., and Grasso, P. (1981). Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its lexicological significance to man. Food Chem. Toxicol. 19, 585-605.
-
(1981)
Food Chem. Toxicol.
, vol.19
, pp. 585-605
-
-
Cohen, A.J.1
Grasso, P.2
-
15
-
-
0345361564
-
Toxicokinetics (TK) of di-n-butylphthalate (DBF) in rats, mice and hamsters
-
Collins, B. J., Buckley Kedderis, L., Grizzle, T. B., Ghoehl, T. J., Handy, R. W., and Marsman, D. S. (1995). Toxicokinetics (TK) of di-n-butylphthalate (DBF) in rats, mice and hamsters. Int. Toxicologist VII, 47-P-13.
-
(1995)
Int. Toxicologist
, vol.7
-
-
Collins, B.J.1
Buckley Kedderis, L.2
Grizzle, T.B.3
Ghoehl, T.J.4
Handy, R.W.5
Marsman, D.S.6
-
16
-
-
0024521714
-
Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di (2-ethylhexyl)phthalate and Wy-14,643
-
Conway, J. G., Tomaszewski, K. E., Olson, M. J., et al. (1989). Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di (2-ethylhexyl)phthalate and Wy-14,643. Carcinogenesis 3, 513-519.
-
(1989)
Carcinogenesis
, vol.3
, pp. 513-519
-
-
Conway, J.G.1
Tomaszewski, K.E.2
Olson, M.J.3
-
17
-
-
0029807538
-
Rat 17β-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene
-
Corton, J. C., Bocos, C., Moreno, E. S., et al. (1996). Rat 17β-hydroxysteroid dehydrogenase type IV is a novel peroxisome proliferator-inducible gene. Mol. Pharmacol. 50, 1157-1166.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1157-1166
-
-
Corton, J.C.1
Bocos, C.2
Moreno, E.S.3
-
18
-
-
0020067649
-
Light and electron microscopy of liver in hyperlipoproteinemic patients under long-term gemfibrozil treatment
-
De La Iglesia, F. A., Lewis, J. E., Buchanan, R. A., Marcus, L. E., and McMahon, G. (1982). Light and electron microscopy of liver in hyperlipoproteinemic patients under long-term gemfibrozil treatment. Atherosclerosis 43, 19-37.
-
(1982)
Atherosclerosis
, vol.43
, pp. 19-37
-
-
De La Iglesia, F.A.1
Lewis, J.E.2
Buchanan, R.A.3
Marcus, L.E.4
McMahon, G.5
-
19
-
-
0000101746
-
PPAR: A key factor in nutrient/ gene interactions
-
P. Baeuerle, Ed., Birkhäuser, Boston
-
Desvergne, B., and Wahli, W. (1995). PPAR: A key factor in nutrient/ gene interactions. In Inducible Transcription (P. Baeuerle, Ed.), Vol. 1, pp. 142-176. Birkhäuser, Boston.
-
(1995)
Inducible Transcription
, vol.1
, pp. 142-176
-
-
Desvergne, B.1
Wahli, W.2
-
20
-
-
0029661982
-
The PPARα-leukotriene B4 pathway to inflammation control
-
Devchand, P. R., Keller, H., Peters, J. M., Vazquez, M., Gonzalez, F. J., and Wahli, W. (1996). The PPARα-leukotriene B4 pathway to inflammation control. Nature 384, 39-43.
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vazquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
21
-
-
0026517010
-
Control of the peroxisome beta oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer, D., Krey, G., Keller, H., Givel, F., Helftenbein, G., and Wahli, W. (1992). Control of the peroxisome beta oxidation pathway by a novel family of nuclear hormone receptors. Cell 68, 879-887.
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, D.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
22
-
-
0343076366
-
Differential enzyme inducing activity of peroxisome proliferators in the male syrian hamster
-
Durnford, J. M., Brody, R. S., Hejtmancik, M. R., Kurtz, P. J., Renne, R. A., Gideon, K M., and Marsman, D. S. (1995). Differential enzyme inducing activity of peroxisome proliferators in the male syrian hamster. Int. Toxicologist VII, 47-P-4.
-
(1995)
Int. Toxicologist
, vol.7
-
-
Durnford, J.M.1
Brody, R.S.2
Hejtmancik, M.R.3
Kurtz, P.J.4
Renne, R.A.5
Gideon, K.M.6
Marsman, D.S.7
-
23
-
-
0025816839
-
Hepatocellular DNA synthesis in rats given peroxisome proliferating agents -comparison of Wy-14,643 to clofibric acid, nafenopin and LY171883
-
Eacho, P. I., Lanier, T. I., and Brodhecker, C. A. (1991). Hepatocellular DNA synthesis in rats given peroxisome proliferating agents -comparison of Wy-14,643 to clofibric acid, nafenopin and LY171883. Carcinogenesis 12(9), 1557-1561.
-
(1991)
Carcinogenesis
, vol.12
, Issue.9
, pp. 1557-1561
-
-
Eacho, P.I.1
Lanier, T.I.2
Brodhecker, C.A.3
-
24
-
-
0345602001
-
Species differences in peroxisome proliferation
-
Elcombe, C. R., and Styles, J. A. (1989). Species differences in peroxisome proliferation. Toxicologist 9, 63.
-
(1989)
Toxicologist
, vol.9
, pp. 63
-
-
Elcombe, C.R.1
Styles, J.A.2
-
25
-
-
0030465619
-
Peroxisome Proliferators: Species differences in response of primary hepatocyte cultures
-
Elcombe, C. R., Bell, D. R., Elias, E., Hasmail, S. C., and Plant, J. P. (1997). Peroxisome Proliferators: Species differences in response of primary hepatocyte cultures. Ann. N.Y. Acad. Sci. 804, 628-635.
-
(1997)
Ann. N.Y. Acad. Sci.
, vol.804
, pp. 628-635
-
-
Elcombe, C.R.1
Bell, D.R.2
Elias, E.3
Hasmail, S.C.4
Plant, J.P.5
-
26
-
-
0028972025
-
15-Deoxy-delta(12,14)-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR-gamma
-
Forman, B. M., Tontonoz, P., Chen, J., Brun, R. P., Speigelman, B. M., and Evans, R. M. (1995). 15-Deoxy-delta(12,14)-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR-gamma. Cell 83, 803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Speigelman, B.M.5
Evans, R.M.6
-
27
-
-
33646295521
-
Liver protein changes in B6C3F1 mice and Syrian hamsters treated with the peroxisome proliferator Wy-14,643
-
Giometti, C. S., Tollaksen, S. L., and Marsman, D. S. (1995). Liver protein changes in B6C3F1 mice and Syrian hamsters treated with the peroxisome proliferator Wy-14,643. Int. Toxicologist VII, 47-P-5.
-
(1995)
Int. Toxicologist
, vol.7
-
-
Giometti, C.S.1
Tollaksen, S.L.2
Marsman, D.S.3
-
28
-
-
0022549354
-
Peroxisome proliferators and lipid peroxidation in rat liver
-
Goel, S. K, Lalwani, N. D., and Reddy, J. K. (1986). Peroxisome proliferators and lipid peroxidation in rat liver. Cancer Res. 46,1324-1330.
-
(1986)
Cancer Res.
, vol.46
, pp. 1324-1330
-
-
Goel, S.K.1
Lalwani, N.D.2
Reddy, J.K.3
-
29
-
-
0027158389
-
Enhancement of peroxisomal enzymes, cytochrome p450 and DNA syntheses in putative preneoplastic foci of rat liver treated with the peroxisome proliferator nafenopin
-
Grasl-Kraupp, B., Huber, W., Just, W., Gibson, G., and Schulte-Hermann, R. (1993). Enhancement of peroxisomal enzymes, cytochrome p450 and DNA syntheses in putative preneoplastic foci of rat liver treated with the peroxisome proliferator nafenopin. Carcinogenesis 14(5), 1007-1012.
-
(1993)
Carcinogenesis
, vol.14
, Issue.5
, pp. 1007-1012
-
-
Grasl-Kraupp, B.1
Huber, W.2
Just, W.3
Gibson, G.4
Schulte-Hermann, R.5
-
30
-
-
1842288938
-
Toxicokinetics (TK) of 2,4-dichlorophenoxyacetic acid (2,4-D) in rats, mice and hamsters
-
Grizzle, T. B., Buckley Kedderis, L., Collins, B. J., Goehl, T. J., Handy, R. W., and Marsman, D. S. (1995). Toxicokinetics (TK) of 2,4-dichlorophenoxyacetic acid (2,4-D) in rats, mice and hamsters. Int. Toxicologist VII, 47-P-9.
-
(1995)
Int. Toxicologist
, vol.7
-
-
Grizzle, T.B.1
Buckley Kedderis, L.2
Collins, B.J.3
Goehl, T.J.4
Handy, R.W.5
Marsman, D.S.6
-
31
-
-
0018831740
-
Effects of p-chlorophenoxyisobutyric acid (CPIB) on the human liver
-
Hanefeld, M., Kemmer, C. H., Leonhardt, W., Kunze, K. D., Jaross, W., and Haller, H. (1980). Effects of p-chlorophenoxyisobutyric acid (CPIB) on the human liver. Atherosclerosis 36, 159-172.
-
(1980)
Atherosclerosis
, vol.36
, pp. 159-172
-
-
Hanefeld, M.1
Kemmer, C.H.2
Leonhardt, W.3
Kunze, K.D.4
Jaross, W.5
Haller, H.6
-
32
-
-
0028998129
-
Mode of action of peroxisome proliferators as hypolipidemic drugs
-
Hertz, R., Bishara-Shieban, J., and Bar-Tana, J. (1995). Mode of action of peroxisome proliferators as hypolipidemic drugs. J. Biol. Chem. 270, 13470-13475.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13470-13475
-
-
Hertz, R.1
Bishara-Shieban, J.2
Bar-Tana, J.3
-
33
-
-
0029381347
-
Effect of phenobarbital and the peroxisome proliferator ciprofibrate on glutamyltranspeptidase activity and leukotriene C4 concentration in cultured rat hepatocytes
-
Hong, J. T., Wilson, M. W., and Glauert, H. P. (1995). Effect of phenobarbital and the peroxisome proliferator ciprofibrate on glutamyltranspeptidase activity and leukotriene C4 concentration in cultured rat hepatocytes. J. Biochem. Toxicol. 10(5), 239-243.
-
(1995)
J. Biochem. Toxicol.
, vol.10
, Issue.5
, pp. 239-243
-
-
Hong, J.T.1
Wilson, M.W.2
Glauert, H.P.3
-
35
-
-
0027525576
-
The PPAR:RXR heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
-
Issemann, L, Prince, R. A., Tugwood, J. D., and Green, S. (1993). The PPAR:RXR heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrinol. 11, 37-47.
-
(1993)
J. Mol. Endocrinol.
, vol.11
, pp. 37-47
-
-
Issemann, L.1
Prince, R.A.2
Tugwood, J.D.3
Green, S.4
-
36
-
-
0029776373
-
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis
-
James, H. H., and Roberts, R. A. (1996). Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis. Carcinogenesis 17, 1623-1632.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1623-1632
-
-
James, H.H.1
Roberts, R.A.2
-
37
-
-
0028865305
-
Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome proliferator-activated receptor genes
-
Jones, P. S., Savory, R., Barratt, P., Bell, A. R., Gray, T. J. B., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Bell, D. R. (1995). Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome proliferator-activated receptor genes. Ear. J. Biochem. 233, 219-226.
-
(1995)
Ear. J. Biochem.
, vol.233
, pp. 219-226
-
-
Jones, P.S.1
Savory, R.2
Barratt, P.3
Bell, A.R.4
Gray, T.J.B.5
Jenkins, N.A.6
Gilbert, D.J.7
Copeland, N.G.8
Bell, D.R.9
-
38
-
-
0024323931
-
Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator
-
Kasai, H., Okada, Y., Nishimura, S., Rao, M. S., and Reddy, J. K. (1989). Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. Cancer Res. 49, 2603-2605.
-
(1989)
Cancer Res.
, vol.49
, pp. 2603-2605
-
-
Kasai, H.1
Okada, Y.2
Nishimura, S.3
Rao, M.S.4
Reddy, J.K.5
-
39
-
-
0027447461
-
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
-
Keller, H., Dreyer, C., Medin, J., Mahfoudi, A., Ozato, K, and Wahli, W. (1993). Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl. Acad. Sci. USA 90, 2160-2164.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2160-2164
-
-
Keller, H.1
Dreyer, C.2
Medin, J.3
Mahfoudi, A.4
Ozato, K.5
Wahli, W.6
-
40
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors
-
Kliewer, S. A., Umesono, K., Noonan, D. J., Hyman, R. A., and Evans, R. M. (1992). Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors. Nature 358, 771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Hyman, R.A.4
Evans, R.M.5
-
41
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S. A., Lenhard, J. M., Willson, T. M., Patel, L, Morris, D. C., and Lehmann, J. M. (1995). A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83, 813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, L.4
Morris, D.C.5
Lehmann, J.M.6
-
42
-
-
0025363455
-
Tumor promotion by the peroxisome proliferator nafenopin involving a specific subtype of altered foci in rat liver
-
Kraupp-Grasl, B., Huber, W., Putz, B., Gerbracht, U., and Schulte, H. R. (1990). Tumor promotion by the peroxisome proliferator nafenopin involving a specific subtype of altered foci in rat liver. Cancer Res. 50(12), 3701-3708.
-
(1990)
Cancer Res.
, vol.50
, Issue.12
, pp. 3701-3708
-
-
Kraupp-Grasl, B.1
Huber, W.2
Putz, B.3
Gerbracht, U.4
Schulte, H.R.5
-
43
-
-
0023234291
-
Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl) phthalate of hepatic enzyme activities and lipid peroxidation in the rat
-
Lake, B. G., Kozlen, S. L., Evans, J. G., Gray, T. J. B., Young, P. J., and Gangolli, S. D. (1987). Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl) phthalate of hepatic enzyme activities and lipid peroxidation in the rat. Toxicology 44, 213-228.
-
(1987)
Toxicology
, vol.44
, pp. 213-228
-
-
Lake, B.G.1
Kozlen, S.L.2
Evans, J.G.3
Gray, T.J.B.4
Young, P.J.5
Gangolli, S.D.6
-
44
-
-
0027881805
-
Comparison of the hepatic effects of nafenopin and Wy-14,643 on peroxisome proliferation and cell replication in the rat and Syrian hamster
-
Lake, B. G., Evans, J. G., Cunninghame, M. E., and Price, R. J. (1993). Comparison of the hepatic effects of nafenopin and Wy-14,643 on peroxisome proliferation and cell replication in the rat and Syrian hamster. Environ. Health Perspect. 101(Suppl. 5), 241-248.
-
(1993)
Environ. Health Perspect.
, vol.101
, Issue.5 SUPPL.
, pp. 241-248
-
-
Lake, B.G.1
Evans, J.G.2
Cunninghame, M.E.3
Price, R.J.4
-
45
-
-
0028987876
-
Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals
-
Lake, B. G. (1995a). Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals. Anna. Rev. Pharmacol. Toxicol. 35, 483-507.
-
(1995)
Anna. Rev. Pharmacol. Toxicol.
, vol.35
, pp. 483-507
-
-
Lake, B.G.1
-
46
-
-
0029557218
-
Peroxisome proliferation: Current mechanisms relating to non-genotoxic carcinogenesis
-
Lake, B. G. (1995b). Peroxisome proliferation: Current mechanisms relating to non-genotoxic carcinogenesis. Toxicol. Lett. 82/83, 673-681.
-
(1995)
Toxicol. Lett.
, vol.82-83
, pp. 673-681
-
-
Lake, B.G.1
-
47
-
-
0342642249
-
Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 (TFG-β1) gene expression
-
Lake, B. G., Rumsby, P. C., Brown, K L., Price, R. J., and Cunninghame, M. E. (1995). Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 (TFG-β1) gene expression. Toxicologist 15, 241.
-
(1995)
Toxicologist
, vol.15
, pp. 241
-
-
Lake, B.G.1
Rumsby, P.C.2
Brown, K.L.3
Price, R.J.4
Cunninghame, M.E.5
-
48
-
-
0029977518
-
A human peroxisome-proliferation-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs
-
Lambe, K. G., and Tugwood, J. D. (1996). A human peroxisome-proliferation-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs. Eur. J. Biochem. 239, 1-7.
-
(1996)
Eur. J. Biochem.
, vol.239
, pp. 1-7
-
-
Lambe, K.G.1
Tugwood, J.D.2
-
49
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee, S. S. T., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernandez-Salguero, P. M., Westphal, H., and Gonzalez, F. J. (1995). Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15, 3012-3022.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.T.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
50
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for the nuclear receptor PPARγ
-
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995). An antidiabetic thiazolidinedione is a high affinity ligand for the nuclear receptor PPARγ. J. Biol. Chem. 270, 12953-12956.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
51
-
-
0028003839
-
Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids
-
Lemberger, T., Staels, B., Saladin, R., Desvergne, B., Auwerx, J., and Wahli, W. (1994). Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids. J. Biol. Chem. 269, 24527-24530.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24527-24530
-
-
Lemberger, T.1
Staels, B.2
Saladin, R.3
Desvergne, B.4
Auwerx, J.5
Wahli, W.6
-
52
-
-
0030060358
-
Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm
-
Lemberger, T., Saladin, R., Vázquez, M., Assimacopoulos, F., Staels, B., Desvergne, B., Wahli, W., and Auwerx, J. (1996). Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm. J. Biol. Chem. 271, 1764-1769.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1764-1769
-
-
Lemberger, T.1
Saladin, R.2
Vázquez, M.3
Assimacopoulos, F.4
Staels, B.5
Desvergne, B.6
Wahli, W.7
Auwerx, J.8
-
53
-
-
0029967121
-
Reduction of the concentrations of prostaglandins e-2 and f-e alpha, and thromboxane b-2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate
-
Leung, L. K., and Glauert, H. P. (1996). Reduction of the concentrations of prostaglandins e-2 and f-e alpha, and thromboxane b-2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. Toxicol. Lett. 85(3), 143-149.
-
(1996)
Toxicol. Lett.
, vol.85
, Issue.3
, pp. 143-149
-
-
Leung, L.K.1
Glauert, H.P.2
-
54
-
-
0344930201
-
NF-κB activity is increased by the peroxisome proliferator ciprofibrate in rats
-
Li, Y., Glauert, H. P., and Spear, B. T. (1996). NF-κB activity is increased by the peroxisome proliferator ciprofibrate in rats. Proc. AACR 37, 160.
-
(1996)
Proc. AACR
, vol.37
, pp. 160
-
-
Li, Y.1
Glauert, H.P.2
Spear, B.T.3
-
55
-
-
0024509605
-
Biochemical mechanisms of induction of hepatic peroxisome proliferation
-
Lock, E. A., Mitchell, A. M., and Elcombe, C. R. (1989). Biochemical mechanisms of induction of hepatic peroxisome proliferation. Anna. Rev. Pharmacol. Toxicol. 29, 145-163.
-
(1989)
Anna. Rev. Pharmacol. Toxicol.
, vol.29
, pp. 145-163
-
-
Lock, E.A.1
Mitchell, A.M.2
Elcombe, C.R.3
-
56
-
-
0024241608
-
Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats
-
Marsman, D. S., Cattley, R. C., Conway, J. G., and Popp, J. A. (1988). Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Cancer Res. 48, 6739-6744.
-
(1988)
Cancer Res.
, vol.48
, pp. 6739-6744
-
-
Marsman, D.S.1
Cattley, R.C.2
Conway, J.G.3
Popp, J.A.4
-
58
-
-
0026631269
-
Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens Wy-14,643 and clofibric acid
-
Marsman, D. S., Goldsworthy, T. L., and Popp, J. A. (1992). Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens Wy-14,643 and clofibric acid. Carcinogenesis 15, 1011-1017.
-
(1992)
Carcinogenesis
, vol.15
, pp. 1011-1017
-
-
Marsman, D.S.1
Goldsworthy, T.L.2
Popp, J.A.3
-
59
-
-
0028339548
-
Apoptosis and chemical carcinogenesis
-
Marsman, D. S., and Barrett, J. C. (1994). Apoptosis and chemical carcinogenesis. Risk Anal. 14(3), 321-326.
-
(1994)
Risk Anal.
, vol.14
, Issue.3
, pp. 321-326
-
-
Marsman, D.S.1
Barrett, J.C.2
-
60
-
-
0028173749
-
Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643
-
Marsman, D. S., and Popp, J. A. (1994). Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643. Carcinogenesis 15, 111-117.
-
(1994)
Carcinogenesis
, vol.15
, pp. 111-117
-
-
Marsman, D.S.1
Popp, J.A.2
-
61
-
-
0344068044
-
Toxicokinetics (TK) of the peroxisome proliferator Wy-14,643 in rats, mice and hamsters
-
Marsman, D. S., Buckley Kedderis, L., Grizzle, T. B., Collins, B. J., Handy, R. W., and Goehl, T. J. (1995). Toxicokinetics (TK) of the peroxisome proliferator Wy-14,643 in rats, mice and hamsters. Int. Toxicologist VII, 47-P-11.
-
(1995)
Int. Toxicologist
, vol.7
-
-
Marsman, D.S.1
Buckley Kedderis, L.2
Grizzle, T.B.3
Collins, B.J.4
Handy, R.W.5
Goehl, T.J.6
-
62
-
-
0029887093
-
Effect on the expression of c-met, c-myc and PPAR-alpha in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator Wy-14,643
-
Miller, R. T., Glover, S. E., Stewart, W. S., Corton, J. C., Popp, J. A., and Cattley, R. C. (1996). Effect on the expression of c-met, c-myc and PPAR-alpha in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator Wy-14,643. Carcinogenesis 17, 1337-1341.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1337-1341
-
-
Miller, R.T.1
Glover, S.E.2
Stewart, W.S.3
Corton, J.C.4
Popp, J.A.5
Cattley, R.C.6
-
63
-
-
33646300574
-
Characterization of regressing peroxisome proliferator-induced hepatocellular adenomas
-
Miller, R. T., and Cattley, R. C. (1996). Characterization of regressing peroxisome proliferator-induced hepatocellular adenomas. Proc. AACR 37, 160.
-
(1996)
Proc. AACR
, vol.37
, pp. 160
-
-
Miller, R.T.1
Cattley, R.C.2
-
64
-
-
0027290892
-
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator responsive element and antagonises peroxisome proliferator mediated signalling
-
Miyata, K. S., Zhang, B., Marcus, S. L., Capone, J. P., and Rachubinski, R. A. (1993). Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator responsive element and antagonises peroxisome proliferator mediated signalling. J. Biol. Chem. 268, 19169-19172.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19169-19172
-
-
Miyata, K.S.1
Zhang, B.2
Marcus, S.L.3
Capone, J.P.4
Rachubinski, R.A.5
-
65
-
-
0026100678
-
Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium
-
Moody, D. E., Reddy, J. K, Lake, B. G., Popp, J. A., and Reese, D. H. (1991). Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium. Fundam. Appl. Toxicol. 16, 233-248.
-
(1991)
Fundam. Appl. Toxicol.
, vol.16
, pp. 233-248
-
-
Moody, D.E.1
Reddy, J.K.2
Lake, B.G.3
Popp, J.A.4
Reese, D.H.5
-
66
-
-
0023755328
-
Comparison of constitutive and inducible levels of expression of peroxisomal betaoxidation and catalase genes in liver and extrahepatic tissue of rat
-
Nemali, M. R., Usuda, N., Reddy, M. K, Oyasu, K., Hashimoto, T., Osumi, T., Rao, M. S., and Reddy, J. K. (1988). Comparison of constitutive and inducible levels of expression of peroxisomal betaoxidation and catalase genes in liver and extrahepatic tissue of rat. Cancer Res. 48, 5316-5324.
-
(1988)
Cancer Res.
, vol.48
, pp. 5316-5324
-
-
Nemali, M.R.1
Usuda, N.2
Reddy, M.K.3
Oyasu, K.4
Hashimoto, T.5
Osumi, T.6
Rao, M.S.7
Reddy, J.K.8
-
67
-
-
0024599877
-
Defferential induction and regulation of peroxisomal enzymes: Predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens
-
Nemali, M. R., Reddy, M. K, Usuda, N., Reddy, P. G., Comeau, L. D., Rao, M. S., and Reddy, J. K. (1989). Defferential induction and regulation of peroxisomal enzymes: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens. Toxicol. Appl. Pharmacol. 97, 72-87.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.97
, pp. 72-87
-
-
Nemali, M.R.1
Reddy, M.K.2
Usuda, N.3
Reddy, P.G.4
Comeau, L.D.5
Rao, M.S.6
Reddy, J.K.7
-
68
-
-
0021244975
-
Clobuzarit: Species differences in the morphological and biochemical response of the liver following chronic administration
-
Orton, T. C., Adam, H. K, Bentley, M., Holloway, B., and Tucker, M. J. (1984). Clobuzarit: Species differences in the morphological and biochemical response of the liver following chronic administration. Toxicol. Appl. Pharmacol. 73, 138-151.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.73
, pp. 138-151
-
-
Orton, T.C.1
Adam, H.K.2
Bentley, M.3
Holloway, B.4
Tucker, M.J.5
-
69
-
-
0028276414
-
Interaction of the peroxisome proliferator-activated receptor α with the retinoid X receptor α unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter
-
Palmer, C. N. A., Hsu, M-H., Muerhoff, A. S., Griffen, K. J., and Johnson, E. F. (1994). Interaction of the peroxisome proliferator-activated receptor α with the retinoid X receptor α unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter. J. Biol. Chem. 269, 18083-18089.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18083-18089
-
-
Palmer, C.N.A.1
Hsu, M.-H.2
Muerhoff, A.S.3
Griffen, K.J.4
Johnson, E.F.5
-
70
-
-
0025793398
-
Testing for induction of DNA synthesis in human hepatocyte primary cultures by rat liver tumor promoters
-
Parzefall, W., Erber, E., Sedivy, R., and Schulte-Hermann, R. (1991). Testing for induction of DNA synthesis in human hepatocyte primary cultures by rat liver tumor promoters. Cancer Res. 51, 1143-1147.
-
(1991)
Cancer Res.
, vol.51
, pp. 1143-1147
-
-
Parzefall, W.1
Erber, E.2
Sedivy, R.3
Schulte-Hermann, R.4
-
71
-
-
0031418657
-
Role of PPAR-α in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
-
in press
-
Peters, J. M., Cattley, R. C., and Gonzalez, F. J. (1997). Role of PPAR-α in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis, in press.
-
(1997)
Carcinogenesis
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
72
-
-
0002083099
-
Peroxisome proliferators as initiators and promoters of rodent hepatocarcinogenesis
-
G. Gibson and B. Lake, Eds., Taylor & Francis, London
-
Popp, J. A., and Cattley, R. C. (1993). Peroxisome proliferators as initiators and promoters of rodent hepatocarcinogenesis. In Peroxisomes: Biology and Importance in Toxicology and Medicine (G. Gibson and B. Lake, Eds.), pp. 653-665. Taylor & Francis, London.
-
(1993)
Peroxisomes: Biology and Importance in Toxicology and Medicine
, pp. 653-665
-
-
Popp, J.A.1
Cattley, R.C.2
-
73
-
-
0018076262
-
Hepatic peroxisome proliferation: Induction by BR-931, a hypolipidemic analog of Wy-14,643
-
Reddy, J. K, Azarnoff, D. L., and Sirtori, C. R. (1978). Hepatic peroxisome proliferation: Induction by BR-931, a hypolipidemic analog of Wy-14,643. Arch. Int. Pharmacodyn. 234, 4-14.
-
(1978)
Arch. Int. Pharmacodyn.
, vol.234
, pp. 4-14
-
-
Reddy, J.K.1
Azarnoff, D.L.2
Sirtori, C.R.3
-
74
-
-
0018345144
-
Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643), in rat and mouse liver
-
Reddy, J. K, Sambasiva Rao, M., Azarnoff, D. L., and Sell, S. (1979). Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643), in rat and mouse liver. Cancer Res. 39, 152-158.
-
(1979)
Cancer Res.
, vol.39
, pp. 152-158
-
-
Reddy, J.K.1
Sambasiva Rao, M.2
Azarnoff, D.L.3
Sell, S.4
-
75
-
-
0021051308
-
Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans
-
Reddy, J. K., and Lalwani, N. D. (1983). Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol. 12, 1-58.
-
(1983)
Crit. Rev. Toxicol.
, vol.12
, pp. 1-58
-
-
Reddy, J.K.1
Lalwani, N.D.2
-
76
-
-
0022560399
-
Comparative pharmacokinetics and subacute toxicity of di-(2-ethylhexyl)phthalate (DEHP) in rats and marmosets: Extrapolation of effects in rodents to man
-
Rhodes, C., Orton, T. C., Pratt, I. S., Batten, P. L., Bratt, H., Jackson, S. J., and Elcombe, C. R. (1986). Comparative pharmacokinetics and subacute toxicity of di-(2-ethylhexyl)phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man. Environ. Health Perspect. 65, 299-308.
-
(1986)
Environ. Health Perspect.
, vol.65
, pp. 299-308
-
-
Rhodes, C.1
Orton, T.C.2
Pratt, I.S.3
Batten, P.L.4
Bratt, H.5
Jackson, S.J.6
Elcombe, C.R.7
-
77
-
-
0029081713
-
Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations
-
Roberts, R. A., Soames, A. R., Gill, J. H., James, N. H., and Wheeldon, E. B. (1995). Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations. Carcinogenesis 16(8), 1693-1698.
-
(1995)
Carcinogenesis
, vol.16
, Issue.8
, pp. 1693-1698
-
-
Roberts, R.A.1
Soames, A.R.2
Gill, J.H.3
James, N.H.4
Wheeldon, E.B.5
-
78
-
-
0023624613
-
Interspecies difference in peroxisomes and peroxisome proliferation
-
Rodricks, J. V., and Turnbull, D. (1987). Interspecies difference in peroxisomes and peroxisome proliferation. Toxicol. Ind. Health 3, 197-212.
-
(1987)
Toxicol. Ind. Health
, vol.3
, pp. 197-212
-
-
Rodricks, J.V.1
Turnbull, D.2
-
79
-
-
0029146746
-
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: Relationship to mitochondrial alterations
-
Sausen, P. J., Lee, D. C., Rose, M. L., and Cattley, R. C. (1995). Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: Relationship to mitochondrial alterations. Carcinogenesis 16(8), 1795-1801.
-
(1995)
Carcinogenesis
, vol.16
, Issue.8
, pp. 1795-1801
-
-
Sausen, P.J.1
Lee, D.C.2
Rose, M.L.3
Cattley, R.C.4
-
80
-
-
0026785388
-
Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
-
Schmidt, A., Endo, N., Rutledge, S. J., Vogel, R., Shinar, D., and Rodan, G. A. (1992). Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol. Endocrinol. 6, 1634-1641.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1634-1641
-
-
Schmidt, A.1
Endo, N.2
Rutledge, S.J.3
Vogel, R.4
Shinar, D.5
Rodan, G.A.6
-
81
-
-
0027191040
-
CDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
-
Sher, T., Yi, H-F., McBride, O. W., and Gonzalez, F. J. (1993). cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry 32, 5598-5604.
-
(1993)
Biochemistry
, vol.32
, pp. 5598-5604
-
-
Sher, T.1
Yi, H.-F.2
McBride, O.W.3
Gonzalez, F.J.4
-
82
-
-
0023887949
-
Chemically induced proliferation of peroxisomes: Implications for risk assessment
-
Stott, W. T. (1988). Chemically induced proliferation of peroxisomes: Implications for risk assessment. Regul. Toxicol. Pharmacol. 8, 125-159.
-
(1988)
Regul. Toxicol. Pharmacol.
, vol.8
, pp. 125-159
-
-
Stott, W.T.1
-
83
-
-
0023769551
-
A species comparison of acute hyperplasia induced by the peroxisome proliferator methylclofenapate: Involvement of the binucleated hepatocyte
-
Styles, J. A., Kelly, M., Pritchard, N. R., and Elcombe, C. R. (1988). A species comparison of acute hyperplasia induced by the peroxisome proliferator methylclofenapate: Involvement of the binucleated hepatocyte. Carcinogenesis 9, 1647-1655.
-
(1988)
Carcinogenesis
, vol.9
, pp. 1647-1655
-
-
Styles, J.A.1
Kelly, M.2
Pritchard, N.R.3
Elcombe, C.R.4
-
84
-
-
0025069871
-
Effects produced by the non-genotoxic hepatocarcinogen methylclofenapate in dwarf mice: Peroxisome induction uncoupled from DNA synthesis and nuclearity changes
-
Styles, J. A., Kelly, M., Pritchard, N. R., and Foster, J. R. (1990). Effects produced by the non-genotoxic hepatocarcinogen methylclofenapate in dwarf mice: Peroxisome induction uncoupled from DNA synthesis and nuclearity changes. Carcinogenesis 11, 387-391.
-
(1990)
Carcinogenesis
, vol.11
, pp. 387-391
-
-
Styles, J.A.1
Kelly, M.2
Pritchard, N.R.3
Foster, J.R.4
-
85
-
-
0025004340
-
Relationship between hepatic peroxisome proliferation and 8-hydroxydeoxyguanosine formation in liver DNA of rats following long-term exposure to three peroxisome proliferators: Di(2-ethylhexyl) phthalate, aluminium clofibrate and simfibrate
-
Takagi, A., Sai, K., Unenura, T., Hasegawa, R., and Kurokawa, Y. (1990). Relationship between hepatic peroxisome proliferation and 8-hydroxydeoxyguanosine formation in liver DNA of rats following long-term exposure to three peroxisome proliferators: di(2-ethylhexyl) phthalate, aluminium clofibrate and simfibrate. Cancer Lett. 53, 33-38.
-
(1990)
Cancer Lett.
, vol.53
, pp. 33-38
-
-
Takagi, A.1
Sai, K.2
Unenura, T.3
Hasegawa, R.4
Kurokawa, Y.5
-
86
-
-
0026761562
-
Studies of early hepatocellular proliferation and peroxisomal proliferation in Sprague-Dawley rats treated with tumorigenic doses of clofibrate
-
Tanaka, K, Smith, P. F., Stromberg, P. C., Eydelloth, R. S., Herold, E. G., Grossman, S. J., Frank, J. D., Hertzog, P. R., Soper, K A., and Keenan, K. P. (1992). Studies of early hepatocellular proliferation and peroxisomal proliferation in Sprague-Dawley rats treated with tumorigenic doses of clofibrate. Toxicol. Appl. Pharmacol. 116(1), 71-77.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.116
, Issue.1
, pp. 71-77
-
-
Tanaka, K.1
Smith, P.F.2
Stromberg, P.C.3
Eydelloth, R.S.4
Herold, E.G.5
Grossman, S.J.6
Frank, J.D.7
Hertzog, P.R.8
Soper, K.A.9
Keenan, K.P.10
-
87
-
-
0028180070
-
MPPAR-gamma2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz, P., Hu, E., Graves, R. A., Budavari, A. I., and Siegelman, B. M. (1994). MPPAR-gamma2: Tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8, 1224-1234.
-
(1994)
Genes Dev.
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Siegelman, B.M.5
-
89
-
-
0026541591
-
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking region of the rat acyl CoA oxidase gene
-
Tugwood, J. D., Issemann, L, Andersen, R. G., Bundell, K. R., McPheat, W. L., and Green, S. (1992). The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking region of the rat acyl CoA oxidase gene. EMBO J. 11, 433-439.
-
(1992)
EMBO J.
, vol.11
, pp. 433-439
-
-
Tugwood, J.D.1
Issemann, L.2
Andersen, R.G.3
Bundell, K.R.4
McPheat, W.L.5
Green, S.6
-
90
-
-
0030454445
-
Peroxisome proliferator activated-receptor: Structures and functions
-
Tugwood, J. D., Aldridge, T. C., Lambe, K. G., MacDonald, N., and Woodyatt, N. J. (1997). Peroxisome proliferator activated-receptor: Structures and functions. Ann. N.Y. Acad. Sci. 804, 252-265.
-
(1997)
Ann. N.Y. Acad. Sci.
, vol.804
, pp. 252-265
-
-
Tugwood, J.D.1
Aldridge, T.C.2
Lambe, K.G.3
MacDonald, N.4
Woodyatt, N.J.5
-
91
-
-
0028036723
-
Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
-
Vu-Dac, N., Schoonjans, K., Laine, B., Fruchart, J., Auwerx, J., and Staels, B. (1994). Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J. Biol. Chem. 269, 31012-31018.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31012-31018
-
-
Vu-Dac, N.1
Schoonjans, K.2
Laine, B.3
Fruchart, J.4
Auwerx, J.5
Staels, B.6
-
92
-
-
0029119082
-
Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor
-
Vu-Dac, N., Schoonjans, K., Kosyth, V., Dallongaville, J., Fruchart, J. C., Staels, B., and Auwerx, J. (1995). Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J. Clin. Invest. 96, 741-750.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 741-750
-
-
Vu-Dac, N.1
Schoonjans, K.2
Kosyth, V.3
Dallongaville, J.4
Fruchart, J.C.5
Staels, B.6
Auwerx, J.7
-
93
-
-
77957177553
-
Dose-related effects of hepatocarcinogen Wy-14,643, on peroxisomes and cell replication
-
Wada, N., Marsman, D. S., and Popp, J. A. (1992). Dose-related effects of hepatocarcinogen Wy-14,643, on peroxisomes and cell replication. Fundam. Appl. Toxicol. 18, 149-154.
-
(1992)
Fundam. Appl. Toxicol.
, vol.18
, pp. 149-154
-
-
Wada, N.1
Marsman, D.S.2
Popp, J.A.3
-
94
-
-
0029018821
-
Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid
-
Wilson, M. W., Lay, L. T., Chow, C. K, Tai, H. H., Robertson, L. W., and Glauert, H. P. (1995). Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid. Arch. Toxicol. 69(7), 491-497.
-
(1995)
Arch. Toxicol.
, vol.69
, Issue.7
, pp. 491-497
-
-
Wilson, M.W.1
Lay, L.T.2
Chow, C.K.3
Tai, H.H.4
Robertson, L.W.5
Glauert, H.P.6
-
95
-
-
0026756096
-
Identification of a peroxisome proliferator responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydrates/3-hydroxyacyl-CoA dehydrogenase
-
Zhang, B., Marcus, S. L., Fereydoun, G. S., Alvares, K., Reddy, J. K., Subramani, S., Rachubinski, R. A., and Capone, J. P. (1992). Identification of a peroxisome proliferator responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydrates/3-hydroxyacyl-CoA dehydrogenase. Proc. Natl. Acad. Sci. USA 89, 7541-7545.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7541-7545
-
-
Zhang, B.1
Marcus, S.L.2
Fereydoun, G.S.3
Alvares, K.4
Reddy, J.K.5
Subramani, S.6
Rachubinski, R.A.7
Capone, J.P.8
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