Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes

Toxicological Sciences

Volumn 78, Issue 2, 2004, Pages 229-240

  Ammerschlaeger, Manuel ^a   Beigel, Jürgen ^a   Klein, Kai Uwe ^a,b   Mueller, Stefan O ^a  

^a MERCK KGAA   (Germany)

^b GenPharmTox BioTech AG   (Germany)

Author keywords

FAO; Fibrates; HepG2; PPAR ; Primary hepatocytes; Wy 14643

Indexed keywords

ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE; CATALASE; CIPROFIBRATE; DNA; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEROXISOME; RAT; REPORTER GENE; SPECIES DIFFERENCE;

ACYL-COA OXIDASE; ANIMALS; CARNITINE ACYLTRANSFERASES; CATALASE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CLOFIBRATE; CLOFIBRIC ACID; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; MALE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PEROXISOME PROLIFERATORS; PROMOTER REGIONS (GENETICS); PYRIMIDINES; RATS; RATS, WISTAR; RESPONSE ELEMENTS; SPECIES SPECIFICITY; TRANSFECTION;

RODENTIA;

EID: 2342428577     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh071     Document Type: Article

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