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Volumn 38, Issue 8, 2013, Pages 719-728

Do polymorphisms in the TAS1R1 gene contribute to broader differences in human taste intensity?

Author keywords

Bitter; Rs17492553; Rs34160967; Salty; Sour; Supertasting; Sweet; Taste genetics

Indexed keywords

ADENINE; CITRIC ACID; CYTOSINE; GUANINE; QUININE; SODIUM CHLORIDE; SUCROSE; THYMINE;

EID: 84884387839     PISSN: 0379864X     EISSN: 14643553     Source Type: Journal    
DOI: 10.1093/chemse/bjt040     Document Type: Article
Times cited : (21)

References (60)
  • 1
    • 5044222204 scopus 로고    scopus 로고
    • How did alternative splicing evolve
    • Ast G. 2004. How did alternative splicing evolve?. Nat Rev Genet. 5(10):773-782.
    • (2004) Nat Rev Genet , vol.5 , Issue.10 , pp. 773-782
    • Ast, G.1
  • 2
    • 37049215868 scopus 로고
    • On the Sense of Taste
    • Bailey EH, Nichols EL. 1888. On the Sense of Taste. Science. 11(268):145-146.
    • (1888) Science , vol.11 , Issue.268 , pp. 145-146
    • Bailey, E.H.1    Nichols, E.L.2
  • 3
    • 84870687886 scopus 로고    scopus 로고
    • Taste damage (otitis media, tonsillectomy and head and neck cancer), oral sensations and BMI
    • Bartoshuk LM, Catalanotto F, Hoffman H, Logan H, Snyder DJ. 2012. Taste damage (otitis media, tonsillectomy and head and neck cancer), oral sensations and BMI. Physiol Behav. 107(4):516-526.
    • (2012) Physiol Behav , vol.107 , Issue.4 , pp. 516-526
    • Bartoshuk, L.M.1    Catalanotto, F.2    Hoffman, H.3    Logan, H.4    Snyder, D.J.5
  • 5
    • 0000336479 scopus 로고
    • Genetics of Sensory Thresholds: Taste for Phenyl Thio Carbamide
    • Blakeslee AF. 1932. Genetics of Sensory Thresholds: Taste for Phenyl Thio Carbamide. Proc Natl Acad Sci U S A. 18(1):120-130.
    • (1932) Proc Natl Acad Sci U S A , vol.18 , Issue.1 , pp. 120-130
    • Blakeslee, A.F.1
  • 6
    • 80053051864 scopus 로고    scopus 로고
    • Polymorphisms in TAS2R38 and the taste bud trophic factor, gustin gene co-operate in modulating PROP taste phenotype
    • Caló C, Padiglia A, Zonza A, Corrias L, Contu P, Tepper BJ, Barbarossa IT. 2011. Polymorphisms in TAS2R38 and the taste bud trophic factor, gustin gene co-operate in modulating PROP taste phenotype. Physiol Behav. 104(5):1065-1071.
    • (2011) Physiol Behav , vol.104 , Issue.5 , pp. 1065-1071
    • Caló, C.1    Padiglia, A.2    Zonza, A.3    Corrias, L.4    Contu, P.5    Tepper, B.J.6    Barbarossa, I.T.7
  • 7
    • 0042242582 scopus 로고    scopus 로고
    • ESEfinder: A web resource to identify exonic splicing enhancers
    • Cartegni L, Wang J, Zhu Z, Zhang MQ, Krainer AR. 2003. ESEfinder: A web resource to identify exonic splicing enhancers. Nucleic Acids Res. 31(13):3568-3571.
    • (2003) Nucleic Acids Res , vol.31 , Issue.13 , pp. 3568-3571
    • Cartegni, L.1    Wang, J.2    Zhu, Z.3    Zhang, M.Q.4    Krainer, A.R.5
  • 8
    • 33751084573 scopus 로고    scopus 로고
    • The receptors and cells for mammalian taste
    • Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS. 2006. The receptors and cells for mammalian taste. Nature. 444(7117):288-294.
    • (2006) Nature , vol.444 , Issue.7117 , pp. 288-294
    • Chandrashekar, J.1    Hoon, M.A.2    Ryba, N.J.3    Zuker, C.S.4
  • 9
    • 0033993988 scopus 로고    scopus 로고
    • A metabotropic glutamate receptor variant functions as a taste receptor
    • Chaudhari N, Landin AM, Roper SD. 2000. A metabotropic glutamate receptor variant functions as a taste receptor. Nat Neurosci. 3(2):113-119.
    • (2000) Nat Neurosci , vol.3 , Issue.2 , pp. 113-119
    • Chaudhari, N.1    Landin, A.M.2    Roper, S.D.3
  • 10
    • 70349573545 scopus 로고    scopus 로고
    • Taste receptors for umami: the case for multiple receptors
    • Chaudhari N, Pereira E, Roper SD. 2009. Taste receptors for umami: the case for multiple receptors. Am J Clin Nutr. 90(3):738S-742S.
    • (2009) Am J Clin Nutr , vol.90 , Issue.3
    • Chaudhari, N.1    Pereira, E.2    Roper, S.D.3
  • 13
    • 84855252084 scopus 로고    scopus 로고
    • dbSNP (Database of Single Nucleotide Polymorphisms)
    • National Center for Biotechnology Information, National Library of Medicine [Internet]. Available from: URL . Last accessed: June 2013.
    • dbSNP (Database of Single Nucleotide Polymorphisms). 2013. National Center for Biotechnology Information, National Library of Medicine [Internet]. Available from: URL http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs17492553;http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=rs34160967. Last accessed: June 2013.
    • (2013)
  • 15
    • 33846706753 scopus 로고    scopus 로고
    • Variation in oral sensation: implications for diet and health
    • Duffy VB. 2007. Variation in oral sensation: implications for diet and health. Curr Opin Gastroenterol. 23(2):171-177.
    • (2007) Curr Opin Gastroenterol , vol.23 , Issue.2 , pp. 171-177
    • Duffy, V.B.1
  • 16
    • 84884400555 scopus 로고    scopus 로고
    • A chemosensory component in the 2012 National Health and Nutrition Examination Survey (NHANES): adults ages 40+ years [abstract]
    • Thirty-fourth Annual Meeting of the Association for Chemoreception Sciences. Huntington Beach (CA) Apr 25-28; Chem Senses.; doi:10.1093/ chemse/bjs091
    • Duffy VB, Doty RL, Hayes JE, Rawal S, Hoffman HJ. 2012. A chemosensory component in the 2012 National Health and Nutrition Examination Survey (NHANES): adults ages 40+ years [abstract]. Thirty-fourth Annual Meeting of the Association for Chemoreception Sciences. Huntington Beach (CA) 29 p; 2013 Apr 25-28; Chem Senses.; doi:10.1093/ chemse/bjs091. 19 p.
    • (2012) , pp. 19
    • Duffy, V.B.1    Doty, R.L.2    Hayes, J.E.3    Rawal, S.4    Hoffman, H.J.5
  • 17
    • 78649479812 scopus 로고    scopus 로고
    • Vegetable Intake in College-Aged Adults Is Explained by Oral Sensory Phenotypes and TAS2R38 Genotype
    • Duffy VB, Hayes JE, Davidson AC, Kidd JR, Kidd KK, Bartoshuk LM. 2010. Vegetable Intake in College-Aged Adults Is Explained by Oral Sensory Phenotypes and TAS2R38 Genotype. Chemosens Percept. 3(3-4):137-148.
    • (2010) Chemosens Percept , vol.3 , Issue.3-4 , pp. 137-148
    • Duffy, V.B.1    Hayes, J.E.2    Davidson, A.C.3    Kidd, J.R.4    Kidd, K.K.5    Bartoshuk, L.M.6
  • 18
    • 68649117890 scopus 로고    scopus 로고
    • Surveying food and beverage liking: a tool for epidemiological studies to connect chemosensation with health outcomes
    • Duffy VB, Hayes JE, Sullivan BS, Faghri P. 2009. Surveying food and beverage liking: a tool for epidemiological studies to connect chemosensation with health outcomes. Ann N Y Acad Sci. 1170:558-568.
    • (2009) Ann N Y Acad Sci , vol.1170 , pp. 558-568
    • Duffy, V.B.1    Hayes, J.E.2    Sullivan, B.S.3    Faghri, P.4
  • 19
    • 3242708298 scopus 로고    scopus 로고
    • Associations between taste genetics, oral sensation and alcohol intake
    • Duffy VB, Peterson JM, Bartoshuk LM. 2004. Associations between taste genetics, oral sensation and alcohol intake. Physiol Behav. 82(2-3):435-445.
    • (2004) Physiol Behav , vol.82 , Issue.2-3 , pp. 435-445
    • Duffy, V.B.1    Peterson, J.M.2    Bartoshuk, L.M.3
  • 20
    • 0345016453 scopus 로고    scopus 로고
    • Lingual tactile acuity, taste perception, and the density and diameter of fungiform papillae in female subjects
    • Essick GK, Chopra A, Guest S, McGlone F. 2003. Lingual tactile acuity, taste perception, and the density and diameter of fungiform papillae in female subjects. Physiol Behav. 80(2-3):289-302.
    • (2003) Physiol Behav , vol.80 , Issue.2-3 , pp. 289-302
    • Essick, G.K.1    Chopra, A.2    Guest, S.3    McGlone, F.4
  • 21
    • 0002892867 scopus 로고
    • Taste teception in the Pacific bottlenose dolphin (Tursiops Truncatus Gilli) and the California sea Lion (Zalophus Californianus)
    • In: Thomas JA, Kastelein RA, editors. Sensory abilities of cetaceans: laboratory and field evidence, NATO ASI series. New York: Plenum
    • Friedl WA, Nachtigall PE, Moore PWB, Chun NKW, Haun JE, Hall RW, Richards JL. 1990. Taste teception in the Pacific bottlenose dolphin (Tursiops Truncatus Gilli) and the California sea Lion (Zalophus Californianus). In: Thomas JA, Kastelein RA, editors. Sensory abilities of cetaceans: laboratory and field evidence, NATO ASI series. New York: Plenum. p. 447-454.
    • (1990) , pp. 447-454
    • Friedl, W.A.1    Nachtigall, P.E.2    Moore, P.W.B.3    Chun, N.K.W.4    Haun, J.E.5    Hall, R.W.6    Richards, J.L.7
  • 22
    • 77955861412 scopus 로고    scopus 로고
    • Association between common variation in genes encoding sweet taste signaling components and human sucrose perception
    • Fushan AA, Simons CT, Slack JP, Drayna D. 2010. Association between common variation in genes encoding sweet taste signaling components and human sucrose perception. Chem Senses. 35(7):579-592.
    • (2010) Chem Senses , vol.35 , Issue.7 , pp. 579-592
    • Fushan, A.A.1    Simons, C.T.2    Slack, J.P.3    Drayna, D.4
  • 23
    • 68149137765 scopus 로고    scopus 로고
    • Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose
    • Fushan AA, Simons CT, Slack JP, Manichaikul A, Drayna D. 2009. Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol. 19(15):1288-1293.
    • (2009) Curr Biol , vol.19 , Issue.15 , pp. 1288-1293
    • Fushan, A.A.1    Simons, C.T.2    Slack, J.P.3    Manichaikul, A.4    Drayna, D.5
  • 25
    • 16644383139 scopus 로고    scopus 로고
    • 'Thermal taste' predicts higher responsiveness to chemical taste and flavor
    • Green BG, George P. 2004. 'Thermal taste' predicts higher responsiveness to chemical taste and flavor. Chem Senses. 29(7):617-628.
    • (2004) Chem Senses , vol.29 , Issue.7 , pp. 617-628
    • Green, B.G.1    George, P.2
  • 26
    • 4544325098 scopus 로고    scopus 로고
    • Individual differences in perception of bitterness from capsaicin, piperine and zingerone
    • Green BG, Hayes JE. 2004. Individual differences in perception of bitterness from capsaicin, piperine and zingerone. Chem Senses. 29(1):53-60.
    • (2004) Chem Senses , vol.29 , Issue.1 , pp. 53-60
    • Green, B.G.1    Hayes, J.E.2
  • 27
    • 0035079664 scopus 로고    scopus 로고
    • The genetics of phenylthiocarbamide perception
    • Guo SW, Reed DR. 2001. The genetics of phenylthiocarbamide perception. Ann Hum Biol. 28(2):111-142.
    • (2001) Ann Hum Biol , vol.28 , Issue.2 , pp. 111-142
    • Guo, S.W.1    Reed, D.R.2
  • 28
    • 80053053962 scopus 로고    scopus 로고
    • Two decades of supertasting: where do we stand
    • Hayes JE, Keast RS. 2011. Two decades of supertasting: where do we stand? Physiol Behav. 104(5):1072-1074.
    • (2011) Physiol Behav. , vol.104 , Issue.5 , pp. 1072-1074
    • Hayes, J.E.1    Keast, R.S.2
  • 29
    • 79951805645 scopus 로고    scopus 로고
    • Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults
    • Hayes JE, Wallace MR, Knopik VS, Herbstman DM, Bartoshuk LM, Duffy VB. 2011. Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults. Chem Senses. 36 ,3. 311-319
    • (2011) Chem Senses. , vol.36 , Issue.3 , pp. 311-319
    • Hayes, J.E.1    Wallace, M.R.2    Knopik, V.S.3    Herbstman, D.M.4    Bartoshuk, L.M.5    Duffy, V.B.6
  • 30
    • 84879567052 scopus 로고    scopus 로고
    • Do polymorphisms in chemosensory genes matter for human ingestive behavior
    • Available from: URL
    • Hayes JE, Feeney EL, Allen AL. 2013. Do polymorphisms in chemosensory genes matter for human ingestive behavior? Food Qual. Pref. 30(2): 202-216. Available from: URL http://dx.doi.org/10.1016/j.foodqual.2013.05.013
    • (2013) Food Qual. Pref. , vol.30 , Issue.2 , pp. 202-216
    • Hayes, J.E.1    Feeney, E.L.2    Allen, A.L.3
  • 32
    • 84866643067 scopus 로고    scopus 로고
    • Expression analysis of taste signal transduction molecules in the fungiform and circumvallate papillae of the rhesus macaque, Macaca mulatta
    • Ishimaru Y, Abe M, Asakura T, Imai H, Abe K. 2012. Expression analysis of taste signal transduction molecules in the fungiform and circumvallate papillae of the rhesus macaque, Macaca mulatta. PLoS One. 7(9):e45426.
    • (2012) PLoS One , vol.7 , Issue.9
    • Ishimaru, Y.1    Abe, M.2    Asakura, T.3    Imai, H.4    Abe, K.5
  • 34
    • 0003806547 scopus 로고
    • Design and analysis: a researcher's handbook
    • 3rd ed. Englewood Cliffs (NJ): Prentice Hall
    • Keppel G. 1991. Design and analysis: a researcher's handbook. 3rd ed. Englewood Cliffs (NJ): Prentice Hall.
    • (1991)
    • Keppel, G.1
  • 35
    • 0037458815 scopus 로고    scopus 로고
    • Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide
    • Kim UK, Jorgenson E, Coon H, Leppert M, Risch N, Drayna D. 2003. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science. 299(5610):1221-1225.
    • (2003) Science , vol.299 , Issue.5610 , pp. 1221-1225
    • Kim, U.K.1    Jorgenson, E.2    Coon, H.3    Leppert, M.4    Risch, N.5    Drayna, D.6
  • 36
  • 37
    • 0034063598 scopus 로고    scopus 로고
    • Physiological studies on umami taste
    • Kurihara K, Kashiwayanagi M. 2000. Physiological studies on umami taste. J Nutr. 130(4S Suppl):931S-934S.
    • (2000) J Nutr , vol.130 , Issue.4 S SUPPL.
    • Kurihara, K.1    Kashiwayanagi, M.2
  • 40
    • 0036125560 scopus 로고    scopus 로고
    • A new specific ageusia: some humans cannot taste L-glutamate
    • Lugaz O, Pillias AM, Faurion A. 2002. A new specific ageusia: some humans cannot taste L-glutamate. Chem Senses. 27(2):105-115.
    • (2002) Chem Senses , vol.27 , Issue.2 , pp. 105-115
    • Lugaz, O.1    Pillias, A.M.2    Faurion, A.3
  • 41
    • 78149443848 scopus 로고    scopus 로고
    • Individual differences in AMY1 gene copy number, salivary a-amylase levels, and the perception of oral starch
    • Mandel AL, Peyrotdes Gachons C, Plank KL, Alarcon S, Breslin PA. 2010. Individual differences in AMY1 gene copy number, salivary a-amylase levels, and the perception of oral starch. PLoS One. 5(10):e13352.
    • (2010) PLoS One , vol.5 , Issue.10
    • Mandel, A.L.1    Peyrotdes Gachons, C.2    Plank, K.L.3    Alarcon, S.4    Breslin, P.A.5
  • 42
    • 0025279095 scopus 로고
    • Variations in human taste bud density and taste intensity perception
    • Miller IJ Jr, Reedy FE Jr. 1990. Variations in human taste bud density and taste intensity perception. Physiol Behav. 47(6):1213-1219.
    • (1990) Physiol Behav , vol.47 , Issue.6 , pp. 1213-1219
    • Miller, I.J.1    Reedy, F.E.2
  • 44
    • 77951665700 scopus 로고    scopus 로고
    • Obese women have lower monosodium glutamate taste sensitivity and prefer higher concentrations than do normal-weight women
    • Pepino MY, Finkbeiner S, Beauchamp GK, Mennella JA. 2010. Obese women have lower monosodium glutamate taste sensitivity and prefer higher concentrations than do normal-weight women. Obesity (Silver Spring). 18(5):959-965.
    • (2010) Obesity (Silver Spring) , vol.18 , Issue.5 , pp. 959-965
    • Pepino, M.Y.1    Finkbeiner, S.2    Beauchamp, G.K.3    Mennella, J.A.4
  • 50
    • 0037324514 scopus 로고    scopus 로고
    • An exception to the rule: common vampire bats do not learn taste aversions
    • Ratcliffe JM, Fenton MB, Galef BG. 2003. An exception to the rule: common vampire bats do not learn taste aversions. Ani Behav. 65:385-389.
    • (2003) Ani Behav , vol.65 , pp. 385-389
    • Ratcliffe, J.M.1    Fenton, M.B.2    Galef, B.G.3
  • 51
    • 84884409281 scopus 로고    scopus 로고
    • TAS1R1-intronic SNP associations with liking for dietary sources of glutamate and orosensory intensity [abstract]
    • Thirtyfirst Annual Meeting of the Association for Chemoreception Sciences. Sarasota (FL). 70 p. 2009 Apr 22-26; Chem Senses
    • Rawal S, Wallace MR, Hayes JE, Bartoshuk LM, Langee T, Sholudko A, Duffy VB. 2009. TAS1R1-intronic SNP associations with liking for dietary sources of glutamate and orosensory intensity [abstract]. Thirtyfirst Annual Meeting of the Association for Chemoreception Sciences. Sarasota (FL). 70 p. 2009 Apr 22-26; Chem Senses. 34: A63.
    • (2009) , vol.34
    • Rawal, S.1    Wallace, M.R.2    Hayes, J.E.3    Bartoshuk, L.M.4    Langee, T.5    Sholudko, A.6    Duffy, V.B.7
  • 52
    • 33644552461 scopus 로고    scopus 로고
    • Cloning and characterization of a novel mGluR1 variant from vallate papillae that functions as a receptor for L-glutamate stimuli
    • San Gabriel A, Uneyama H, Yoshie S, Torii K. 2005. Cloning and characterization of a novel mGluR1 variant from vallate papillae that functions as a receptor for L-glutamate stimuli. Chem Senses. 30 (Suppl 1):i25-i26.
    • (2005) Chem Senses , vol.30 , Issue.SUPPL. 1
    • San Gabriel, A.1    Uneyama, H.2    Yoshie, S.3    Torii, K.4
  • 53
    • 69349085520 scopus 로고    scopus 로고
    • Genetic and molecular basis of individual differences in human umami taste perception
    • Shigemura N, Shirosaki S, Sanematsu K, Yoshida R, Ninomiya Y. 2009. Genetic and molecular basis of individual differences in human umami taste perception. PLoS One. 4(8):e6717.
    • (2009) PLoS One , vol.4 , Issue.8
    • Shigemura, N.1    Shirosaki, S.2    Sanematsu, K.3    Yoshida, R.4    Ninomiya, Y.5
  • 54
    • 77957845774 scopus 로고    scopus 로고
    • Variation in umami taste perception in the German and Norwegian population
    • Singh PB, Schuster B, Seo HS. 2010. Variation in umami taste perception in the German and Norwegian population. Eur J Clin Nutr. 64(10):1248-1250.
    • (2010) Eur J Clin Nutr , vol.64 , Issue.10 , pp. 1248-1250
    • Singh, P.B.1    Schuster, B.2    Seo, H.S.3
  • 55
    • 50949091243 scopus 로고    scopus 로고
    • Nutritional implications of genetic taste variation: the role of PROP sensitivity and other taste phenotypes
    • Tepper BJ. 2008. Nutritional implications of genetic taste variation: the role of PROP sensitivity and other taste phenotypes. Annu Rev Nutr. 28:367-388.
    • (2008) Annu Rev Nutr , vol.28 , pp. 367-388
    • Tepper, B.J.1
  • 56
    • 0013339839 scopus 로고
    • Taste Preferences of the Common Vampire Bat (Desmodus-Rotundus)
    • Thompson RD, Elias DJ, Shumake SA, Gaddis SE. 1982. Taste Preferences of the Common Vampire Bat (Desmodus-Rotundus). J Chem Ecol. 8:715-721.
    • (1982) J Chem Ecol , vol.8 , pp. 715-721
    • Thompson, R.D.1    Elias, D.J.2    Shumake, S.A.3    Gaddis, S.E.4
  • 57
  • 58
    • 33646205228 scopus 로고    scopus 로고
    • Phenylthiocarbamide: a 75-year adventure in genetics and natural selection
    • Wooding S. 2006. Phenylthiocarbamide: a 75-year adventure in genetics and natural selection. Genetics. 172(4):2015-2023.
    • (2006) Genetics , vol.172 , Issue.4 , pp. 2015-2023
    • Wooding, S.1
  • 60
    • 84861888731 scopus 로고    scopus 로고
    • Genomic and genetic evidence for the loss of umami taste in bats
    • Zhao H, Xu D, Zhang S, Zhang J. 2012. Genomic and genetic evidence for the loss of umami taste in bats. Genome Biol Evol. 4(1):73-79.
    • (2012) Genome Biol Evol , vol.4 , Issue.1 , pp. 73-79
    • Zhao, H.1    Xu, D.2    Zhang, S.3    Zhang, J.4


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