메뉴 건너뛰기




Volumn 11, Issue 5, 2013, Pages 465-476

Role of wnt signaling in the control of adult hippocampal functioning in health and disease: Therapeutic implications

Author keywords

Alzheime s disease; Hippocampal plasticity; Neurodegeneration; Neurogenesis; Neurorepair; Wnt signaling

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BETA CATENIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DICKKOPF 1 PROTEIN; DISHEVELLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 12; INTERLEUKIN 6; LITHIUM; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYMPHOID ENHANCER FACTOR 1; SECRETED FRIZZLED RELATED PROTEIN 2; STRESS ACTIVATED PROTEIN KINASE; T CELL FACTOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN; WNT11 PROTEIN; WNT4 PROTEIN; WNT5A PROTEIN; WNT7A PROTEIN; WNT7B PROTEIN;

EID: 84884214542     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X11311050001     Document Type: Article
Times cited : (32)

References (140)
  • 1
    • 34249933552 scopus 로고    scopus 로고
    • Anatomical and physiological plasticity of dendritic spines
    • Alvarez, V.A., Sabatini, B.L. Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci, 2007, 30, 79-97.
    • (2007) Annu Rev Neurosci , vol.30 , pp. 79-97
    • Alvarez, V.A.1    Sabatini, B.L.2
  • 2
    • 37549057603 scopus 로고    scopus 로고
    • Structural plasticity of axon terminals in the adult
    • Gogolla, N., Galimberti, I., Caroni, P. Structural plasticity of axon terminals in the adult. Curr. Opin. Neurobiol, 2007, 17(5), 516-524.
    • (2007) Curr. Opin. Neurobiol , vol.17 , Issue.5 , pp. 516-524
    • Gogolla, N.1    Galimberti, I.2    Caroni, P.3
  • 3
    • 65649086782 scopus 로고    scopus 로고
    • Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus
    • Gogolla, N., Galimberti, I., Deguchi, Y., Caroni, P. Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron, 2009, 62(4), 510-525.
    • (2009) Neuron , vol.62 , Issue.4 , pp. 510-525
    • Gogolla, N.1    Galimberti, I.2    Deguchi, Y.3    Caroni, P.4
  • 4
    • 79952071138 scopus 로고    scopus 로고
    • Wnt signaling during synaptic development and plasticity
    • Budnik V, Salinas PC. Wnt signaling during synaptic development and plasticity. Curr. Opin. Neurobiol., 2011, 21(1), 151-159.
    • (2011) Curr. Opin. Neurobiol , vol.21 , Issue.1 , pp. 151-159
    • Budnik, V.1    Salinas, P.C.2
  • 5
    • 48249110960 scopus 로고    scopus 로고
    • Wnt signaling in neural circuit assembly
    • Salinas, P.C., Zou, Y. Wnt signaling in neural circuit assembly. Annu. Rev. Neurosci., 2008, 31, 339-358.
    • (2008) Annu. Rev. Neurosci , vol.31 , pp. 339-358
    • Salinas, P.C.1    Zou, Y.2
  • 6
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • Rosenzweig, E.S., Barnes, C.A. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog. Neurobiol., 2003, 69(3), 143-179.
    • (2003) Prog. Neurobiol , vol.69 , Issue.3 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 7
    • 9644262551 scopus 로고    scopus 로고
    • Alzheimer's disease as a disorder of dynamic brain self-organization
    • Arendt T. Alzheimer's disease as a disorder of dynamic brain self-organization. Prog. Brain Res., 2005, 147, 355-378.
    • (2005) Prog. Brain Res , vol.147 , pp. 355-378
    • Arendt, T.1
  • 8
    • 0031004888 scopus 로고    scopus 로고
    • Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: Evidence for anterograde axonal transport
    • Conner, J.M., Lauterborn, J.C., Yan, Q., Gall, C.M., Varon, S. Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J. Neurosci., 1997, 17(7), 2295-2313.
    • (1997) J. Neurosci , vol.17 , Issue.7 , pp. 2295-2313
    • Conner, J.M.1    Lauterborn, J.C.2    Yan, Q.3    Gall, C.M.4    Varon, S.5
  • 9
    • 4544290086 scopus 로고    scopus 로고
    • Epigenetic control of neurobehavioural plasticity: The role of neurotrophins
    • Branchi, I., Francia, N., Alleva, E. Epigenetic control of neurobehavioural plasticity: the role of neurotrophins. Behav. Pharmacol., 2004, 15(5-6), 353-362.
    • (2004) Behav. Pharmacol , vol.15 , Issue.5 , pp. 353-362
    • Branchi, I.1    Francia, N.2    Alleva, E.3
  • 10
    • 77956647795 scopus 로고    scopus 로고
    • Signaling in adult neurogenesis
    • Mu, Y., Lee, S.W., Gage, F.H. Signaling in adult neurogenesis. Curr. Opin. Neurobiol., 2010, 20(4), 416-423.
    • (2010) Curr. Opin. Neurobiol , vol.20 , Issue.4 , pp. 416-423
    • Mu, Y.1    Lee, S.W.2    Gage, F.H.3
  • 11
    • 80054807478 scopus 로고    scopus 로고
    • RGS14 at the interface of hippocampal signaling and synaptic plasticity
    • Vellano, C.P., Lee, S.E., Dudek, S.M., Hepler, J.R. RGS14 at the interface of hippocampal signaling and synaptic plasticity. Trends Pharmacol. Sci., 2011, 32(11), 666-674.
    • (2011) Trends Pharmacol. Sci , vol.32 , Issue.11 , pp. 666-674
    • Vellano, C.P.1    Lee, S.E.2    Dudek, S.M.3    Hepler, J.R.4
  • 12
    • 0033850796 scopus 로고    scopus 로고
    • Wnt signaling function in Alzheimer's disease
    • De Ferrari, G.V., Inestrosa, N.C. Wnt signaling function in Alzheimer's disease. Brain Res. Rev., 2000, 33(1), 1-12.
    • (2000) Brain Res. Rev , vol.33 , Issue.1 , pp. 1-12
    • de Ferrari, G.V.1    Inestrosa, N.C.2
  • 14
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan, C.Y., Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev.Cell Dev. Biol., 2004, 20, 781-810.
    • (2004) Annu. Rev.Cell Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 16
    • 84875870451 scopus 로고    scopus 로고
    • Wnt Signaling in Vertebrate Neural Development and Function
    • Sep 27, Epub ahead of print
    • Mulligan, K.A., Cheyette, B.N. Wnt Signaling in Vertebrate Neural Development and Function. J. Neuroimmune Pharmacol., 2012, Sep 27 [Epub ahead of print]
    • (2012) J. Neuroimmune Pharmacol
    • Mulligan, K.A.1    Cheyette, B.N.2
  • 18
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • van Amerongen, R., Nusse, R. Towards an integrated view of Wnt signaling in development. Development, 2009, 136(19), 3205-3214.
    • (2009) Development , vol.136 , Issue.19 , pp. 3205-3214
    • van Amerongen, R.1    Nusse, R.2
  • 19
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B.T., Tamai, K., He, X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell, 2009, 17(1), 9-26.
    • (2009) Dev. Cell , vol.17 , Issue.1 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 21
    • 84864353742 scopus 로고    scopus 로고
    • Wnt signaling in development and disease
    • Yang, Y. Wnt signaling in development and disease. Cell Biosci., 2012, 2(1), 14.
    • (2012) Cell Biosci , vol.2 , Issue.1 , pp. 14
    • Yang, Y.1
  • 23
    • 80053466165 scopus 로고    scopus 로고
    • Wnt/Ca2+ signaling pathway: A brief overview
    • Shanghai
    • De, A. Wnt/Ca2+ signaling pathway: a brief overview. Acta Biochim. Biophys. Sin (Shanghai), 2011, 43(10), 745-756.
    • (2011) Acta Biochim. Biophys. Sin , vol.43 , Issue.10 , pp. 745-756
    • De, A.1
  • 24
    • 84861869253 scopus 로고    scopus 로고
    • The tangled web of non-canonical Wnt signalling in neural migration
    • Clark, C.E., Nourse, C.C., Cooper, H.M. The tangled web of non-canonical Wnt signalling in neural migration. Neurosignals, 2012, 20(3), 202-220.
    • (2012) Neurosignals , vol.20 , Issue.3 , pp. 202-220
    • Clark, C.E.1    Nourse, C.C.2    Cooper, H.M.3
  • 25
    • 2342453952 scopus 로고    scopus 로고
    • Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex
    • Shimogori, T., VanSant, J., Paik, E., Grove, E.A. Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex. J. Comp. Neurol., 2004, 473(4), 496-510.
    • (2004) J. Comp. Neurol , vol.473 , Issue.4 , pp. 496-510
    • Shimogori, T.1    Vansant, J.2    Paik, E.3    Grove, E.A.4
  • 27
    • 57249086469 scopus 로고    scopus 로고
    • Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation
    • Davis, E.K., Zou, Y., Ghosh, A. Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation. Neural Dev., 2008, 3, 32.
    • (2008) Neural Dev , vol.3 , pp. 32
    • Davis, E.K.1    Zou, Y.2    Ghosh, A.3
  • 28
    • 77953310084 scopus 로고    scopus 로고
    • Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis
    • Sahores, M., Gibb, A., Salinas, P.C. Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis. Development, 2010, 137(13), 2215-2225.
    • (2010) Development , vol.137 , Issue.13 , pp. 2215-2225
    • Sahores, M.1    Gibb, A.2    Salinas, P.C.3
  • 29
    • 0035019117 scopus 로고    scopus 로고
    • Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon
    • Kim, A.S., Lowenstein, D.H., Pleasure, S.J. Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon. Mech Dev, 2001, 103(1-2), 167-172.
    • (2001) Mech Dev , vol.103 , Issue.1 , pp. 167-172
    • Kim, A.S.1    Lowenstein, D.H.2    Pleasure, S.J.3
  • 30
    • 10644276907 scopus 로고    scopus 로고
    • Frizzled-9 Promoter Drives Expression of Transgenes In the Medial Wall of the Cortex and Its Chief Derivative the Hippocampus
    • Zhao, C., Pleasure, S.J. Frizzled-9 promoter drives expression of transgenes in the medial wall of the cortex and its chief derivative the hippocampus.Genesis, 2004, 40(1), 32-39.
    • (2004) Genesis , vol.40 , Issue.1 , pp. 32-39
    • Zhao, C.1    Pleasure, S.J.2
  • 31
    • 0030933978 scopus 로고    scopus 로고
    • Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
    • Leyns, L., Bouwmeester, T., Kim, S.H., Piccolo, S., De Robertis, E.M. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell, 1997, 88(6), 747-756.
    • (1997) Cell , vol.88 , Issue.6 , pp. 747-756
    • Leyns, L.1    Bouwmeester, T.2    Kim, S.H.3    Piccolo, S.4    de Robertis, E.M.5
  • 32
    • 0030892061 scopus 로고    scopus 로고
    • Secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8
    • Wang, S., Krinks, M., Lin, K., Luyten, F.P., Moos, M., Frz A. Secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell, 1997, 88(6), 757-766.
    • (1997) Cell , vol.88 , Issue.6 , pp. 757-766
    • Wang, S.1    Krinks, M.2    Lin, K.3    Luyten, F.P.4    Moos, M.5    Frz, A.6
  • 33
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • Niehrs, C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene, 2006, 25(57), 7469-7481.
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7469-7481
    • Niehrs, C.1
  • 35
    • 84866092742 scopus 로고    scopus 로고
    • Secreted and Transmembrane Wnt Inhibitors and Activators
    • Cruciat, C.M., Niehrs, C. Secreted and Transmembrane Wnt Inhibitors and Activators. Cold Spring Harb Perspect Biol., 2013, 5(3), a015081.
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , Issue.3
    • Cruciat, C.M.1    Niehrs, C.2
  • 36
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signaling pathway
    • Kawano, Y., Kypta, R. Secreted antagonists of the Wnt signaling pathway. J. Cell Sci., 2003, 116(13), 2627-2634.
    • (2003) J. Cell Sci , vol.116 , Issue.13 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 37
    • 42549096546 scopus 로고    scopus 로고
    • Beyond Wnt inhibition: New functions of secreted Frizzled-related proteins in development and disease
    • Bovolenta, P., Esteve, P., Ruiz, J.M., Cisneros, E., Lopez-Rios, J. Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J. Cell Sci., 2008, 121(6), 737-746.
    • (2008) J. Cell Sci , vol.121 , Issue.6 , pp. 737-746
    • Bovolenta, P.1    Esteve, P.2    Ruiz, J.M.3    Cisneros, E.4    Lopez-Rios, J.5
  • 39
    • 0036500653 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death
    • Grotewold, L., Rüther, U. The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J, 2002, 21(5), 966-975.
    • (2002) EMBO J , vol.21 , Issue.5 , pp. 966-975
    • Grotewold, L.1    Rüther, U.2
  • 40
    • 0034732151 scopus 로고    scopus 로고
    • Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53
    • Wang, J., Shou, J., Chen, X. Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. Oncogene, 2000, 19(14), 1843-1848.
    • (2000) Oncogene , vol.19 , Issue.14 , pp. 1843-1848
    • Wang, J.1    Shou, J.2    Chen, X.3
  • 41
    • 0033966405 scopus 로고    scopus 로고
    • A local Wnt-3a signal is required for development of the mammalian hippocampus
    • Lee, S.M., Tole, S., Grove, E., McMahon, A.P. A local Wnt-3a signal is required for development of the mammalian hippocampus. Development, 2000, 127(3), 457-467.
    • (2000) Development , vol.127 , Issue.3 , pp. 457-467
    • Lee, S.M.1    Tole, S.2    Grove, E.3    McMahon, A.P.4
  • 42
    • 0033950382 scopus 로고    scopus 로고
    • Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1
    • Galceran, J., Miyashita-Lin, E.M., Devaney, E., Rubenstein, J.L., Grosschedl, R. Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development, 2000, 127(3), 469-482.
    • (2000) Development , vol.127 , Issue.3 , pp. 469-482
    • Galceran, J.1    Miyashita-Lin, E.M.2    Devaney, E.3    Rubenstein, J.L.4    Grosschedl, R.5
  • 43
    • 0034611695 scopus 로고    scopus 로고
    • Hippocampus formation: An intriguing collaboration
    • Roelink, H. Hippocampus formation: an intriguing collaboration. Curr. Biol., 2000, 10(7), 279-281.
    • (2000) Curr. Biol , vol.10 , Issue.7 , pp. 279-281
    • Roelink, H.1
  • 44
    • 0142164968 scopus 로고    scopus 로고
    • Role of beta-catenin in the developing cortical and hippocampal neuroepithelium
    • Machon, O., van den Bout, C.J., Backman, M., Kemler, R., Krauss, S. Role of beta-catenin in the developing cortical and hippocampal neuroepithelium. Neuroscience, 2003, 122(1), 129-143.
    • (2003) Neuroscience , vol.122 , Issue.1 , pp. 129-143
    • Machon, O.1    van den Bout, C.J.2    Backman, M.3    Kemler, R.4    Krauss, S.5
  • 45
    • 46949083191 scopus 로고    scopus 로고
    • Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool
    • Solberg, N., Machon, O., Krauss, S. Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. Dev. Dyn., 2008, 237(7), 1799-1811.
    • (2008) Dev. Dyn , vol.237 , Issue.7 , pp. 1799-1811
    • Solberg, N.1    Machon, O.2    Krauss, S.3
  • 46
    • 28844474493 scopus 로고    scopus 로고
    • Retrograde signalling at the synapse: A role for Wnt proteins
    • Salinas, P.C. Retrograde signalling at the synapse: a role for Wnt proteins. Biochem. Soc. Trans, 2005a, 33(6), 1295-1298.
    • (2005) Biochem. Soc. Trans , vol.33 , Issue.6 , pp. 1295-1298
    • Salinas, P.C.1
  • 47
    • 23444455643 scopus 로고    scopus 로고
    • Signaling at the vertebrate synapse: New roles for embryonic morphogens
    • Salinas, P.C. Signaling at the vertebrate synapse: new roles for embryonic morphogens?, J. Neurobiol., 2005b, 64(4), 435-445.
    • (2005) J. Neurobiol , vol.64 , Issue.4 , pp. 435-445
    • Salinas, P.C.1
  • 48
    • 17844366846 scopus 로고    scopus 로고
    • WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
    • Erratum in: Nat. Rev. Neurosci., 2005, 6(7), 582
    • Ciani, L., Salinas, P.C. WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat Rev Neurosci, 2005, 6(5), 351-362. Erratum in: Nat. Rev. Neurosci., 2005, 6(7), 582.
    • (2005) Nat Rev Neurosci , vol.6 , Issue.5 , pp. 351-362
    • Ciani, L.1    Salinas, P.C.2
  • 50
    • 34548234925 scopus 로고    scopus 로고
    • The synaptic Wnt signaling hypothesis
    • Tang, S.J. The synaptic Wnt signaling hypothesis. Synapse, 2007, 61(10), 866-868.
    • (2007) Synapse , vol.61 , Issue.10 , pp. 866-868
    • Tang, S.J.1
  • 51
    • 75549087261 scopus 로고    scopus 로고
    • Emerging roles of Wnts in the adult nervous system
    • Inestrosa, N.C., Arenas, E. Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci, 2010, 11(2), 77-86.
    • (2010) Nat Rev Neurosci , vol.11 , Issue.2 , pp. 77-86
    • Inestrosa, N.C.1    Arenas, E.2
  • 52
    • 84863913174 scopus 로고    scopus 로고
    • Wnt signaling in the vertebrate central nervous system: From axon guidance to synaptic function
    • Salinas P.C. Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function. Cold Spring Harb Perspect Biol., 2012, 4(2), a008003.
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , Issue.2
    • Salinas, P.C.1
  • 53
    • 84862228318 scopus 로고    scopus 로고
    • WNTs in synapse formation and neuronal circuitry
    • Park, M., Shen, K. WNTs in synapse formation and neuronal circuitry. EMBO J, 2012, 31(12), 2697-2704.
    • (2012) EMBO J , vol.31 , Issue.12 , pp. 2697-2704
    • Park, M.1    Shen, K.2
  • 54
    • 0242384747 scopus 로고    scopus 로고
    • Beta-catenin is critical for dendritic morphogenesis
    • Yu, X., Malenka, R.C. Beta-catenin is critical for dendritic morphogenesis. Nat. Neurosci, 2003, 6(11), 1169-1177.
    • (2003) Nat. Neurosci , vol.6 , Issue.11 , pp. 1169-1177
    • Yu, X.1    Malenka, R.C.2
  • 55
    • 33744900895 scopus 로고    scopus 로고
    • Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2
    • Wayman, G.A., Impey, S., Marks, D., Saneyoshi, T., Grant, W.F., Derkach, V., Soderling, T.R. Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron, 2006, 50(6), 897-909.
    • (2006) Neuron , vol.50 , Issue.6 , pp. 897-909
    • Wayman, G.A.1    Impey, S.2    Marks, D.3    Saneyoshi, T.4    Grant, W.F.5    Derkach, V.6    Soderling, T.R.7
  • 56
    • 16644381829 scopus 로고    scopus 로고
    • Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
    • Rosso, S.B., Sussman, D., Wynshaw-Boris, A., Salinas, P.C. Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat. Neurosci., 2005, 8(1), 34-42.
    • (2005) Nat. Neurosci , vol.8 , Issue.1 , pp. 34-42
    • Rosso, S.B.1    Sussman, D.2    Wynshaw-Boris, A.3    Salinas, P.C.4
  • 58
    • 34249108600 scopus 로고    scopus 로고
    • Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons
    • Farías, G.G., Vallés, A.S., Colombres, M., Godoy, J.A., Toledo, E.M., Lukas, R.J., Barrantes, F.J., Inestrosa, N.C. Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons. J. Neurosci., 2007, 27(20), 5313-5325.
    • (2007) J. Neurosci , vol.27 , Issue.20 , pp. 5313-5325
    • Farías, G.G.1    Vallés, A.S.2    Colombres, M.3    Godoy, J.A.4    Toledo, E.M.5    Lukas, R.J.6    Barrantes, F.J.7    Inestrosa, N.C.8
  • 59
    • 84859195359 scopus 로고    scopus 로고
    • Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system
    • Jensen, M., Hoerndli, F.J., Brockie, P.J., Wang, R., Johnson, E., Maxfield, D., Francis, M.M., Madsen, D.M., Maricq, A.V. Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system. Cell, 2012, 149(1), 173-187.
    • (2012) Cell , vol.149 , Issue.1 , pp. 173-187
    • Jensen, M.1    Hoerndli, F.J.2    Brockie, P.J.3    Wang, R.4    Johnson, E.5    Maxfield, D.6    Francis, M.M.7    Madsen, D.M.8    Maricq, A.V.9
  • 63
    • 35649000005 scopus 로고    scopus 로고
    • Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95
    • Kim, M.J., Futai, K., Jo, J., Hayashi, Y., Cho, K., Sheng, M. Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Neuron, 2007, 56(3), 488-502.
    • (2007) Neuron , vol.56 , Issue.3 , pp. 488-502
    • Kim, M.J.1    Futai, K.2    Jo, J.3    Hayashi, Y.4    Cho, K.5    Sheng, M.6
  • 65
    • 73949158445 scopus 로고    scopus 로고
    • Wnt signaling modulates pre- and postsynaptic maturation: Therapeutic considerations
    • Farías, G.G., Godoy, J.A., Cerpa, W., Varela-Nallar, L., Inestrosa, N.C. Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations. Dev. Dyn., 2010, 239(1), 94-101.
    • (2010) Dev. Dyn , vol.239 , Issue.1 , pp. 94-101
    • Farías, G.G.1    Godoy, J.A.2    Cerpa, W.3    Varela-Nallar, L.4    Inestrosa, N.C.5
  • 66
    • 34248570158 scopus 로고    scopus 로고
    • Synaptotoxicity in Alzheimer's disease: The Wnt signaling pathway as a molecular target
    • Inestrosa, N. C, Varela-Nallar, L., Grabowski, C.P., Colombres, M. Synaptotoxicity in Alzheimer's disease: the Wnt signaling pathway as a molecular target. IUBMB Life, 2007, 59(4-5), 316-321.
    • (2007) IUBMB Life , vol.59 , Issue.4 , pp. 316-321
    • Inestrosa, N.C.1    Varela-Nallar, L.2    Grabowski, C.P.3    Colombres, M.4
  • 67
    • 77249117920 scopus 로고    scopus 로고
    • Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons
    • Cerpa, W., Farías, G.G., Godoy, J.A., Fuenzalida, M., Bonansco, C, Inestrosa, N.C. Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Mol. Neurodegener., 2010, 18(5), 3.
    • (2010) Mol. Neurodegener , vol.18 , Issue.5 , pp. 3
    • Cerpa, W.1    Farías, G.G.2    Godoy, J.A.3    Fuenzalida, M.4    Bonansco, C.5    Inestrosa, N.C.6
  • 69
    • 84860223907 scopus 로고    scopus 로고
    • Wnt-5a is a synaptogenic factor with neuroprotective properties against A(3 toxicity
    • Varela-Nallar, L., Parodi, J., Farías, G.G., Inestrosa, N.C. Wnt-5a is a synaptogenic factor with neuroprotective properties against A(3 toxicity. Neurodegener. Dis., 2012, 10(1-4), 23-26.
    • (2012) Neurodegener. Dis , vol.10 , Issue.1 , pp. 23-26
    • Varela-Nallar, L.1    Parodi, J.2    Farías, G.G.3    Inestrosa, N.C.4
  • 70
    • 78650506425 scopus 로고    scopus 로고
    • Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses
    • U. S. A
    • Varela-Nallar, L., Alfaro, I.E., Serrano, F.G, Parodi, J, Inestrosa, N.C. Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses. Proc. Natl. Acad. Sci. U. S. A., 2010, 107(49), 21164-21169.
    • (2010) Proc. Natl. Acad. Sci , vol.107 , Issue.49 , pp. 21164-21169
    • Varela-Nallar, L.1    Alfaro, I.E.2    Serrano, F.G.3    Parodi, J.4    Inestrosa, N.C.5
  • 71
    • 33744958556 scopus 로고    scopus 로고
    • Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation
    • Chen, J., Park, C.S., Tang, S.J. Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation. J. Biol. Chem., 2006, 281(17), 11910-11916.
    • (2006) J. Biol. Chem , vol.281 , Issue.17 , pp. 11910-11916
    • Chen, J.1    Park, C.S.2    Tang, S.J.3
  • 73
    • 34548215222 scopus 로고    scopus 로고
    • Notch signalling becomes transiently attenuated during long-term memory consolidation in adult Wistar rats
    • Conboy, L., Seymour, C.M., Monopoli, M.P., O'Sullivan, N.C., Murphy, K.J., Regan, C.M. Notch signalling becomes transiently attenuated during long-term memory consolidation in adult Wistar rats. Neurobiol. Learn Mem., 2007, 88(3), 342-351.
    • (2007) Neurobiol. Learn Mem , vol.88 , Issue.3 , pp. 342-351
    • Conboy, L.1    Seymour, C.M.2    Monopoli, M.P.3    O'Sullivan, N.C.4    Murphy, K.J.5    Regan, C.M.6
  • 74
    • 82555174660 scopus 로고    scopus 로고
    • Synaptic stimulation of mTOR is mediated by Wnt signaling and regulation of glycogen synthetase kinase-3
    • Ma, T., Tzavaras, N., Tsokas, P., Landau, E.M., Blitzer, R.D. Synaptic stimulation of mTOR is mediated by Wnt signaling and regulation of glycogen synthetase kinase-3. J. Neurosci., 2011, 31(48), 17537-17546.
    • (2011) J. Neurosci , vol.31 , Issue.48 , pp. 17537-17546
    • Ma, T.1    Tzavaras, N.2    Tsokas, P.3    Landau, E.M.4    Blitzer, R.D.5
  • 78
    • 0035175495 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons
    • See, V., Boutillier, A.L., Bito, H., Loeffler, J.P. Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons. FASEB J, 2001, 15, 134-144.
    • (2001) FASEB J , vol.15 , pp. 134-144
    • See, V.1    Boutillier, A.L.2    Bito, H.3    Loeffler, J.P.4
  • 81
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • Deng, W., Aimone, J.B., Gage, F.H. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat. Rev. Neurosci., 2010, 11(5), 339-350.
    • (2010) Nat. Rev. Neurosci , vol.11 , Issue.5 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 83
    • 0037135177 scopus 로고    scopus 로고
    • Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
    • Chenn, A., Walsh, C.A. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science, 2002, 297(5580), 365-369.
    • (2002) Science , vol.297 , Issue.5580 , pp. 365-369
    • Chenn, A.1    Walsh, C.A.2
  • 84
    • 3242889925 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells
    • Hirabayashi, Y., Itoh, Y., Tabata, H., Nakajima, K., Akiyama, T., Masuyama, N., Gotoh, Y. The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development, 2004, 131(12), 2791-2801.
    • (2004) Development , vol.131 , Issue.12 , pp. 2791-2801
    • Hirabayashi, Y.1    Itoh, Y.2    Tabata, H.3    Nakajima, K.4    Akiyama, T.5    Masuyama, N.6    Gotoh, Y.7
  • 85
    • 84884219572 scopus 로고    scopus 로고
    • Neural Stem/Progenitor Cell Proliferation and Differentiation: Role of Sonic Hedgehog and Wingless/Int-1 proteins
    • Ed.; MAH Springer
    • Anderova, M., Honsa, P. Neural Stem/Progenitor Cell Proliferation and Differentiation: Role of Sonic Hedgehog and Wingless/Int-1 proteins. In: Stem Cells and Cancer Stem Cells; Ed.; MAH Springer, 2012; pp. 3-18.
    • (2012) Stem Cells and Cancer Stem Cells , pp. 3-18
    • Anderova, M.1    Honsa, P.2
  • 86
    • 78149302213 scopus 로고    scopus 로고
    • Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal
    • sup pp 1-9
    • Qu, Q., Sun, G., Li, W., Yang, S., Ye, P., Zhao, C., Yu, R.T., Gage, F.H., Evans, R.M., Shi, Y. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol, 2010, 12(1), 31-40, sup pp 1-9.
    • (2010) Nat Cell Biol , vol.12 , Issue.1 , pp. 31-40
    • Qu, Q.1    Sun, G.2    Li, W.3    Yang, S.4    Ye, P.5    Zhao, C.6    Yu, R.T.7    Gage, F.H.8    Evans, R.M.9    Shi, Y.10
  • 90
    • 80053927984 scopus 로고    scopus 로고
    • Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis
    • Okamoto, M., Inoue, K., Iwamura, H., Terashima, K., Soya, H., Asashima, M., Kuwabara, T. Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis. FASEB J, 2011, 25(10), 3570-3582.
    • (2011) FASEB J , vol.25 , Issue.10 , pp. 3570-3582
    • Okamoto, M.1    Inoue, K.2    Iwamura, H.3    Terashima, K.4    Soya, H.5    Asashima, M.6    Kuwabara, T.7
  • 91
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer, T.D., Willhoite, A.R., Gage, F.H. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neuro., 2000, 425(4), 479-494.
    • (2000) J. Comp. Neuro , vol.425 , Issue.4 , pp. 479-494
    • Palmer, T.D.1    Willhoite, A.R.2    Gage, F.H.3
  • 94
    • 0037007647 scopus 로고    scopus 로고
    • Astroglia induce neurogenesis from adult neural stem cells
    • Song, H., Stevens, C.F., Gage, F.H. Astroglia induce neurogenesis from adult neural stem cells. Nature, 2002, 417(6884), 39-44.
    • (2002) Nature , vol.417 , Issue.6884 , pp. 39-44
    • Song, H.1    Stevens, C.F.2    Gage, F.H.3
  • 95
    • 33746255997 scopus 로고    scopus 로고
    • Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation
    • Barkho, B.Z., Song, H., Aimone, J.B., Smrt, R.D., Kuwabara, T., Nakashima, K., Gage, F.H., Zhao, X. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev., 2006, 15(3), 407-421.
    • (2006) Stem Cells Dev , vol.15 , Issue.3 , pp. 407-421
    • Barkho, B.Z.1    Song, H.2    Aimone, J.B.3    Smrt, R.D.4    Kuwabara, T.5    Nakashima, K.6    Gage, F.H.7    Zhao, X.8
  • 96
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • Kuhn, H.G., Dickinson-Anson, H., Gage, F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci., 1996, 16(6), 2027-2033.
    • (1996) J. Neurosci , vol.16 , Issue.6 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 97
    • 36749037197 scopus 로고    scopus 로고
    • Diminished adult neurogenesis in the marmoset brain precedes old age
    • Leuner, B., Kozorovitskiy, Y., Gross, C.G., Gould, E. Diminished adult neurogenesis in the marmoset brain precedes old age. PNAS, 1997, 104, 17169-17173.
    • (1997) PNAS , vol.104 , pp. 17169-17173
    • Leuner, B.1    Kozorovitskiy, Y.2    Gross, C.G.3    Gould, E.4
  • 98
    • 78249267229 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus
    • Gage, F.H. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. Keio J Med, 2010, 59(3), 79-83.
    • (2010) Keio J Med , vol.59 , Issue.3 , pp. 79-83
    • Gage, F.H.1
  • 99
    • 84856805691 scopus 로고    scopus 로고
    • GSK3 as a Sensor Determining Cell Fate in the Brain
    • Cole, A.R. GSK3 as a Sensor Determining Cell Fate in the Brain. Front Mol. Neurosci., 2012, 5, 4.
    • (2012) Front Mol. Neurosci , vol.5 , pp. 4
    • Cole, A.R.1
  • 100
    • 78649844418 scopus 로고    scopus 로고
    • Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus
    • Imura, T., Wang, X., Noda, T., Sofroniew, M.V., Fushiki, S. Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus. Stem Cells, 2010, 28(11), 2053-2064.
    • (2010) Stem Cells , vol.28 , Issue.11 , pp. 2053-2064
    • Imura, T.1    Wang, X.2    Noda, T.3    Sofroniew, M.V.4    Fushiki, S.5
  • 101
    • 0033609561 scopus 로고    scopus 로고
    • Increased expression of Wnt-1 in schizophrenic brains
    • Miyaoka, T., Seno, H., Ishino, H. Increased expression of Wnt-1 in schizophrenic brains. Schizophr. Res., 1999, 38, 1-6.
    • (1999) Schizophr. Res , vol.38 , pp. 1-6
    • Miyaoka, T.1    Seno, H.2    Ishino, H.3
  • 102
    • 84855297758 scopus 로고    scopus 로고
    • Signaling pathways underlying the pathophysiology and treatment of depression: Novel mechanisms for rapid-acting agents
    • Duman, R.S., Voleti, B. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends Neurosci., 2012, 35(1), 47-56.
    • (2012) Trends Neurosci , vol.35 , Issue.1 , pp. 47-56
    • Duman, R.S.1    Voleti, B.2
  • 106
    • 0036884291 scopus 로고    scopus 로고
    • Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway
    • Garrido, J.L., Godoy, J.A., Alvarez, A., Bronfman, M., Inestrosa, N.C. Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway. FASEB J, 2002, 16(14), 1982-1984.
    • (2002) FASEB J , vol.16 , Issue.14 , pp. 1982-1984
    • Garrido, J.L.1    Godoy, J.A.2    Alvarez, A.3    Bronfman, M.4    Inestrosa, N.C.5
  • 111
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • Jope, R.S. Anti-bipolar therapy: mechanism of action of lithium. J. Mol. Psychiatry, 1999, 4(2), 117-128.
    • (1999) J. Mol. Psychiatry , vol.4 , Issue.2 , pp. 117-128
    • Jope, R.S.1
  • 113
    • 82755189437 scopus 로고    scopus 로고
    • Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression
    • Voleti, B., Tanis, K.Q., Newton, S.S., Duman, R.S. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression. Biol. Psychiatry, 2012, 71(1), 51-58.
    • (2012) Biol. Psychiatry , vol.71 , Issue.1 , pp. 51-58
    • Voleti, B.1    Tanis, K.Q.2    Newton, S.S.3    Duman, R.S.4
  • 116
    • 0035911156 scopus 로고    scopus 로고
    • Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing
    • Soriano, S., Kang, D.E., Fu, M., Pestel, L R., Chevallier, N., Zheng, H., Koo, EH. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. J Cell Biol, 2001, 152(4), 785-794.
    • (2001) J Cell Biol , vol.152 , Issue.4 , pp. 785-794
    • Soriano, S.1    Kang, D.E.2    Fu, M.3    Pestel, L.R.4    Chevallier, N.5    Zheng, H.6    Koo, E.H.7
  • 117
    • 0037118247 scopus 로고    scopus 로고
    • Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
    • Jackson, G.R., Wiedau-Pazos, M., Sang, T.K., Wagle, N., Brown, C.A., Massachi, S., Geschwind, D.H. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron, 2002, 34(4), 509-519.
    • (2002) Neuron , vol.34 , Issue.4 , pp. 509-519
    • Jackson, G.R.1    Wiedau-Pazos, M.2    Sang, T.K.3    Wagle, N.4    Brown, C.A.5    Massachi, S.6    Geschwind, D.H.7
  • 119
    • 84857870160 scopus 로고    scopus 로고
    • The secreted Wnt antagonist Dickkopf-1 is required for amyloid p-mediated synaptic loss
    • Purro, S.A., Dickins, E.M., Salinas, P.C. The secreted Wnt antagonist Dickkopf-1 is required for amyloid p-mediated synaptic loss. J. Neurosci, 2012, 32, 3492-3498.
    • (2012) J. Neurosci , vol.32 , pp. 3492-3498
    • Purro, S.A.1    Dickins, E.M.2    Salinas, P.C.3
  • 120
    • 79959223383 scopus 로고    scopus 로고
    • GSK3 Function in the Brain during Development, Neuronal Plasticity, and Neurodegeneration
    • 2011
    • Salcedo-Tello, P., Ortiz-Matamoros, A., Arias, C. GSK3 Function in the Brain during Development, Neuronal Plasticity, and Neurodegeneration. Int. J. Alzheimers Dis., 2011, 2011:189728.
    • (2011) Int. J. Alzheimers Dis , pp. 189728
    • Salcedo-Tello, P.1    Ortiz-Matamoros, A.2    Arias, C.3
  • 121
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3p regulates production of Alzheimer's disease amyloid-beta peptides
    • Phiel, C.J., Wilson, C.A., Lee, V.M., Klein, P.S. GSK-3p regulates production of Alzheimer's disease amyloid-beta peptides. Nature, 2003, 423(6938), 435-439.
    • (2003) Nature , vol.423 , Issue.6938 , pp. 435-439
    • Phiel, C.J.1    Wilson, C.A.2    Lee, V.M.3    Klein, P.S.4
  • 122
    • 2642552331 scopus 로고    scopus 로고
    • Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
    • Su, Y., Ryder, J., Li, B., Wu, X., Fox, N., Solenberg, P., Brune, K., Paul, S., Zhou, Y., Liu, F., Ni, B. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry, 2004, 43(22), 6899-6908.
    • (2004) Biochemistry , vol.43 , Issue.22 , pp. 6899-6908
    • Su, Y.1    Ryder, J.2    Li, B.3    Wu, X.4    Fox, N.5    Solenberg, P.6    Brune, K.7    Paul, S.8    Zhou, Y.9    Liu, F.10    Ni, B.11
  • 127
  • 131
    • 46249120721 scopus 로고    scopus 로고
    • Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: Role of tau phosphorylation
    • Mercado-Gómez, O., Hernández-Fonseca, K., Villavicencio-Queijeiro, A., Massieu, L., Chimal-Monroy, J., Arias, C. Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: role of tau phosphorylation. Neurochem. Res., 2008, 33(8), 1599-1609.
    • (2008) Neurochem. Res. , vol.33 , Issue.8 , pp. 1599-1609
    • Mercado-Gómez, O.1    Hernández-Fonseca, K.2    Villavicencio-Queijeiro, A.3    Massieu, L.4    Chimal-Monroy, J.5    Arias, C.6
  • 132
    • 80051772933 scopus 로고    scopus 로고
    • WNT5A signaling contributes to Ap-induced neuroinflammation and neurotoxicity
    • Li, B., Zhong, L., Yang, X., Andersson, T., Huang, M., Tang, S.J. WNT5A signaling contributes to Ap-induced neuroinflammation and neurotoxicity. PLoS One, 2011, 6(8), e22920.
    • (2011) PLoS One , vol.6 , Issue.8
    • Li, B.1    Zhong, L.2    Yang, X.3    Andersson, T.4    Huang, M.5    Tang, S.J.6
  • 133
    • 0038434118 scopus 로고    scopus 로고
    • Aging and glial responses to lipopolysaccharide in vitro: Greater induction of IL-1 and IL-6, but smaller induction of neurotoxicity
    • Xie, Z., Morgan, T.E., Rozovsky, I., Finch, C.E. Aging and glial responses to lipopolysaccharide in vitro: greater induction of IL-1 and IL-6, but smaller induction of neurotoxicity. Exp Neurol, 2003, 182(1), 135-141.
    • (2003) Exp Neurol , vol.182 , Issue.1 , pp. 135-141
    • Xie, Z.1    Morgan, T.E.2    Rozovsky, I.3    Finch, C.E.4
  • 134
    • 77953290880 scopus 로고    scopus 로고
    • Long-term changes in neuronal degeneration and microglial activation in the hippocampal CA1 region after experimental transient cerebral ischemic damage
    • Lee, C.H., Moon, S.M., Yoo, K.Y., Choi, J.H., Park, O.K., Hwang, I.K., Sohn, Y., Moon, J.B., Cho, J.H., Won, M.H. Long-term changes in neuronal degeneration and microglial activation in the hippocampal CA1 region after experimental transient cerebral ischemic damage. Brain Res., 2010, 1342, 138-149.
    • (2010) Brain Res , vol.1342 , pp. 138-149
    • Lee, C.H.1    Moon, S.M.2    Yoo, K.Y.3    Choi, J.H.4    Park, O.K.5    Hwang, I.K.6    Sohn, Y.7    Moon, J.B.8    Cho, J.H.9    Won, M.H.10
  • 136
    • 78650904823 scopus 로고    scopus 로고
    • Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice
    • Fiorentini, A., Rosi, M.C., Grossi, C, Luccarini, I., Casamenti, F. Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice. PLoS One, 2010, 5(12), e14382.
    • (2010) PLoS One , vol.5 , Issue.12
    • Fiorentini, A.1    Rosi, M.C.2    Grossi, C.3    Luccarini, I.4    Casamenti, F.5
  • 138
    • 79960123794 scopus 로고    scopus 로고
    • Wnt1 regulated Frizzled-1/p-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection
    • L'Episcopo, F., Serapide, M.F., Tirolo, C, Testa, N., Caniglia, S., Morale, M.C., Pluchino, S., Marchetti, B. A Wnt1 regulated Frizzled-1/p-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Mol. Neurodegener., 2011, 13(6), 49.
    • (2011) Mol. Neurodegener , vol.13 , Issue.6 , pp. 49
    • L'Episcopo, F.1    Serapide, M.F.2    Tirolo, C.3    Testa, N.4    Caniglia, S.5    Morale, M.C.6    Pluchino, S.7    Marchetti, B.A.8
  • 140
    • 49649094091 scopus 로고    scopus 로고
    • The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease
    • Inestrosa, N.C., Toledo, E.M. The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease. Mol. Neurodegener., 2008, 24(3), 9.
    • (2008) Mol. Neurodegener , vol.24 , Issue.3 , pp. 9
    • Inestrosa, N.C.1    Toledo, E.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.