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Volumn 4, Issue 2, 1999, Pages 117-128

Anti-bipolar therapy: Mechanism of action of lithium

Author keywords

AP 1; Bipolar disorder; Cyclic AMP; Glutamate; Inositol; Lithium

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; LITHIUM; NEUROTRANSMITTER; PROTEIN KINASE C; TRANSCRIPTION FACTOR;

EID: 0032947795     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000494     Document Type: Review
Times cited : (374)

References (150)
  • 1
    • 0023039173 scopus 로고
    • Effects of lithium on phosphoinositide metabolism in vivo
    • Sherman WR, Gish BG, Honchar MP, Munsell LY. Effects of lithium on phosphoinositide metabolism in vivo. Fed Proc 1986; 45: 2639-2646.
    • (1986) Fed Proc , vol.45 , pp. 2639-2646
    • Sherman, W.R.1    Gish, B.G.2    Honchar, M.P.3    Munsell, L.Y.4
  • 2
    • 0023247347 scopus 로고
    • A review of the biochemical and neuro-pharmacological actions of lithium
    • Wood AJ, Goodwin GM. A review of the biochemical and neuro-pharmacological actions of lithium. Psychol Med 1987; 17: 579-600.
    • (1987) Psychol Med , vol.17 , pp. 579-600
    • Wood, A.J.1    Goodwin, G.M.2
  • 3
    • 0027007777 scopus 로고
    • Effects of lithium on second messenger systems in the brain
    • Mork A, Geisler A, Hollund P. Effects of lithium on second messenger systems in the brain. Pharmacol Toxicol 1992; 71: 4-17.
    • (1992) Pharmacol Toxicol , vol.71 , pp. 4-17
    • Mork, A.1    Geisler, A.2    Hollund, P.3
  • 4
    • 0026686359 scopus 로고
    • Transduction of psychosocial stress into the neurobiology of recurrent affective disorder
    • Post RM. Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. Am J Psychiatry 1992; 149: 999-1010.
    • (1992) Am J Psychiatry , vol.149 , pp. 999-1010
    • Post, R.M.1
  • 5
    • 0026831726 scopus 로고
    • The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders
    • Avissar S, Schreiber G. The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders. Biol Psychiatry 1992; 31: 435-459.
    • (1992) Biol Psychiatry , vol.31 , pp. 435-459
    • Avissar, S.1    Schreiber, G.2
  • 7
    • 0028569188 scopus 로고
    • Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity
    • Duman RS, Heninger GR, Nestler EJ. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. J Nerv Ment Dis 1994; 182: 692-700.
    • (1994) J Nerv Ment Dis , vol.182 , pp. 692-700
    • Duman, R.S.1    Heninger, G.R.2    Nestler, E.J.3
  • 8
    • 0028146119 scopus 로고
    • Lithium in the treatment of mood disorders
    • Price LH, Heninger GR. Lithium in the treatment of mood disorders. New Engl J Med 1994; 331: 591-598.
    • (1994) New Engl J Med , vol.331 , pp. 591-598
    • Price, L.H.1    Heninger, G.R.2
  • 9
    • 0028810958 scopus 로고
    • A molecular model for bipolar affective disorder
    • Lachman HM, Papolos DF. A molecular model for bipolar affective disorder. Med Hypoth 1995; 45: 255-264.
    • (1995) Med Hypoth , vol.45 , pp. 255-264
    • Lachman, H.M.1    Papolos, D.F.2
  • 10
    • 0027972567 scopus 로고
    • Long-term action of lithium: A role for transcriptional and posttranscriptional factors regulated by protein kinase C
    • Manji HK, Lenox RH. Long-term action of lithium: a role for transcriptional and posttranscriptional factors regulated by protein kinase C. Synapse 1994; 16: 11-28.
    • (1994) Synapse , vol.16 , pp. 11-28
    • Manji, H.K.1    Lenox, R.H.2
  • 11
    • 0028219225 scopus 로고
    • Lithium and brain signal transduction systems
    • Jope RS, Williams MB. Lithium and brain signal transduction systems. Biochem Pharmacol 1994; 47: 429-441.
    • (1994) Biochem Pharmacol , vol.47 , pp. 429-441
    • Jope, R.S.1    Williams, M.B.2
  • 13
    • 0029875448 scopus 로고    scopus 로고
    • How does lithium work on manic depression? Clinical and psychological correlates of the inositol theory
    • Belmaker RH, Bersudsky Y, Agam G, Levine J, Kofman O. How does lithium work on manic depression? Clinical and psychological correlates of the inositol theory. Annu Rev Med 1996; 47: 47-56.
    • (1996) Annu Rev Med , vol.47 , pp. 47-56
    • Belmaker, R.H.1    Bersudsky, Y.2    Agam, G.3    Levine, J.4    Kofman, O.5
  • 14
    • 0032171402 scopus 로고    scopus 로고
    • The lithium ion: A foundation for psychopharmacological specificity
    • Soares JC, Gershon S. The lithium ion: a foundation for psychopharmacological specificity. Neuropsychopharmacology 1998; 19: 167-182.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 167-182
    • Soares, J.C.1    Gershon, S.2
  • 15
    • 0033013011 scopus 로고    scopus 로고
    • A bimodal model of the mechanism of action of lithium
    • Jope RS. A bimodal model of the mechanism of action of lithium. Mol Psychiatry 1999; 4: 21-25.
    • (1999) Mol Psychiatry , vol.4 , pp. 21-25
    • Jope, R.S.1
  • 16
    • 0026498609 scopus 로고
    • 3H]inositol radioactivity and mass of second messenger inositol 1,4,5-trisphosphate in monkey cerebral cortex slices
    • 3H]inositol radioactivity and mass of second messenger inositol 1,4,5-trisphosphate in monkey cerebral cortex slices. J Neurochem 1992; 59: 2332-2335.
    • (1992) J Neurochem , vol.59 , pp. 2332-2335
    • Dixon, J.F.1    Lee, C.H.2    Los, G.V.3    Hokin, L.E.4
  • 17
    • 0027999029 scopus 로고
    • Lithium stimulates glutamate 'release' and inositol 1,4,5-trisphosphate accumulation via activation of the N-methyl-D-aspartate receptor in monkey and mouse cerebral cortex slices
    • Dixon JF, Los GV, Hokin LE. Lithium stimulates glutamate 'release' and inositol 1,4,5-trisphosphate accumulation via activation of the N-methyl-D-aspartate receptor in monkey and mouse cerebral cortex slices. Proc Natl Acad Sci USA 1994; 91: 8358-8362.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8358-8362
    • Dixon, J.F.1    Los, G.V.2    Hokin, L.E.3
  • 18
    • 0029095921 scopus 로고
    • Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells
    • Los GV, Artemenko IP, Hokin LE. Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells. Biochem J 1995; 311: 225-232.
    • (1995) Biochem J , vol.311 , pp. 225-232
    • Los, G.V.1    Artemenko, I.P.2    Hokin, L.E.3
  • 19
    • 0030978251 scopus 로고    scopus 로고
    • The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates
    • Dixon JF, Hokin LE. The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates. Proc Natl Acad Sci USA 1997; 94: 4757-4760.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4757-4760
    • Dixon, J.F.1    Hokin, L.E.2
  • 20
    • 0032493304 scopus 로고    scopus 로고
    • Lithium acutely inhibits and chronically upregulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex
    • Dixon JF, Hokin LE. Lithium acutely inhibits and chronically upregulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex. Proc Natl Acad Sci USA 1998; 95: 8363-8368.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8363-8368
    • Dixon, J.F.1    Hokin, L.E.2
  • 21
    • 0027199290 scopus 로고
    • Lithium chloride promotes short-term survival of PC12 cells after serum and NGF deprivation
    • Volonte C, Rukenstein A. Lithium chloride promotes short-term survival of PC12 cells after serum and NGF deprivation. Lithium 1993; 4: 211-219.
    • (1993) Lithium , vol.4 , pp. 211-219
    • Volonte, C.1    Rukenstein, A.2
  • 22
    • 0028356703 scopus 로고
    • Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons
    • D'Mello SR, Anelli R, Calissano P. Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons. Exp Cell Res 1994; 211: 332-338.
    • (1994) Exp Cell Res , vol.211 , pp. 332-338
    • D'Mello, S.R.1    Anelli, R.2    Calissano, P.3
  • 23
    • 0028306310 scopus 로고
    • LiCl promotes survival of GABA-ergic neurons from cerebellum and cerebral cortex: LiCl induces survival of GABAergic neurons
    • Volonte C, Ciolti MT, Merlo D. LiCl promotes survival of GABA-ergic neurons from cerebellum and cerebral cortex: LiCl induces survival of GABAergic neurons. Neurosci Lett 1994; 172: 6-10.
    • (1994) Neurosci Lett , vol.172 , pp. 6-10
    • Volonte, C.1    Ciolti, M.T.2    Merlo, D.3
  • 24
    • 0028670432 scopus 로고
    • Lithium protects against ouabain-induced cell death
    • Li R, Shen Y, El-Mallakh RS. Lithium protects against ouabain-induced cell death. Lithium 1994; 5: 211-216.
    • (1994) Lithium , vol.5 , pp. 211-216
    • Li, R.1    Shen, Y.2    El-Mallakh, R.S.3
  • 25
    • 0029364638 scopus 로고
    • Lithium delays the radiation-induced apoptotic process in external granule cells of mouse cerebellum
    • Inouye M, Yamamura H, Nakano A. Lithium delays the radiation-induced apoptotic process in external granule cells of mouse cerebellum. J Radiat Res 1995; 36: 203-208.
    • (1995) J Radiat Res , vol.36 , pp. 203-208
    • Inouye, M.1    Yamamura, H.2    Nakano, A.3
  • 26
    • 0028844373 scopus 로고
    • A protective effect of lithium on rat behavior altered by ibotenic acid lesions of the basal forebrain cholinergic system
    • Pascual T, Gonzalez, JL. A protective effect of lithium on rat behavior altered by ibotenic acid lesions of the basal forebrain cholinergic system. Brain Res 1995; 695: 289-292.
    • (1995) Brain Res , vol.695 , pp. 289-292
    • Pascual, T.1    Gonzalez, J.L.2
  • 27
  • 28
    • 0032478088 scopus 로고    scopus 로고
    • Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
    • Nonaka S, Hough CJ, Chuang D-M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci USA 1998; 95: 2642-2647.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2642-2647
    • Nonaka, S.1    Hough, C.J.2    Chuang, D.-M.3
  • 29
    • 0032557889 scopus 로고    scopus 로고
    • Neuroprotective effects of lithium on focal cerebral ischemia in rats
    • Nonaka S, Chuang D-M. Neuroprotective effects of lithium on focal cerebral ischemia in rats. Neuroreport 1998; 9: 2081-2084.
    • (1998) Neuroreport , vol.9 , pp. 2081-2084
    • Nonaka, S.1    Chuang, D.-M.2
  • 30
    • 0031870871 scopus 로고    scopus 로고
    • Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine
    • Nonaka S, Katsube N, Chuang D-M. Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine. J Pharmacol Exp Ther 1998; 286: 539-547.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 539-547
    • Nonaka, S.1    Katsube, N.2    Chuang, D.-M.3
  • 31
    • 0030773187 scopus 로고    scopus 로고
    • Effects of lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat
    • Sparapani M, Virgili M, Ortali F, Contestabile A. Effects of lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat. Brain Res 1997; 765: 164-168.
    • (1997) Brain Res , vol.765 , pp. 164-168
    • Sparapani, M.1    Virgili, M.2    Ortali, F.3    Contestabile, A.4
  • 32
    • 0031939657 scopus 로고    scopus 로고
    • Synapse-specific accumulation of lithium in intracellular microdomains: A model for uncoupling coincidence detection in the brain
    • Kabakov AY, Karkanias NB, Lenox RH, Papke RL. Synapse-specific accumulation of lithium in intracellular microdomains: a model for uncoupling coincidence detection in the brain. Synapse 1998; 28: 271-279.
    • (1998) Synapse , vol.28 , pp. 271-279
    • Kabakov, A.Y.1    Karkanias, N.B.2    Lenox, R.H.3    Papke, R.L.4
  • 33
    • 0003327576 scopus 로고    scopus 로고
    • A new common transcriptional target for the mood-stabilizing agents lithium and valproic acid
    • Manji HK, Zeng WZ, Huang D, Ikonomov OC, Chen G. A new common transcriptional target for the mood-stabilizing agents lithium and valproic acid. Soc Neurosci Abstr 1997; 23: 2045.
    • (1997) Soc Neurosci Abstr , vol.23 , pp. 2045
    • Manji, H.K.1    Zeng, W.Z.2    Huang, D.3    Ikonomov, O.C.4    Chen, G.5
  • 34
    • 0013489154 scopus 로고    scopus 로고
    • Chronic lithium induces p53 downregulation and bcl-2 upregulation in cerebellar neurons: A potential role in neuroprotection against excitotoxicity
    • Chuang D-M, Chen R-W. Chronic lithium induces p53 downregulation and bcl-2 upregulation in cerebellar neurons: a potential role in neuroprotection against excitotoxicity. Soc Neurosci Abstr 1998; 24: 997.
    • (1998) Soc Neurosci Abstr , vol.24 , pp. 997
    • Chuang, D.-M.1    Chen, R.-W.2
  • 35
    • 0028836585 scopus 로고
    • + stimulates ATP-regulated dopamine uptake in PC12 cells
    • + stimulates ATP-regulaled dopamine uptake in PC12 cells. Neuroscience 1995; 65: 1-4.
    • (1995) Neuroscience , vol.65 , pp. 1-4
    • Dunigan, C.D.1    Shamoo, A.E.2
  • 36
    • 0029827385 scopus 로고    scopus 로고
    • Adaptive changes in the rat dopaminergic transmission following repeated lithium administration
    • Dziedzicka-Wasylewska M, Mackowiak M, Figat K, Wedzony K. Adaptive changes in the rat dopaminergic transmission following repeated lithium administration. J Neural Trans 1996; 103: 765-776.
    • (1996) J Neural Trans , vol.103 , pp. 765-776
    • Dziedzicka-Wasylewska, M.1    Mackowiak, M.2    Figat, K.3    Wedzony, K.4
  • 37
    • 0029955182 scopus 로고    scopus 로고
    • Chronic lithium attenuates dopamine D1-receptor mediated increases in acetylcholine release in rat frontal cortex
    • Acquas E, Fibiger, HC. Chronic lithium attenuates dopamine D1-receptor mediated increases in acetylcholine release in rat frontal cortex. Psychopharmacology 1996; 125: 162-167.
    • (1996) Psychopharmacology , vol.125 , pp. 162-167
    • Acquas, E.1    Fibiger, H.C.2
  • 39
    • 0025971097 scopus 로고
    • Analysis of the convulsant-potentiating effects of lithium
    • Ormandy GC, Song L, Jope RS. Analysis of the convulsant-potentiating effects of lithium. Exp Neurol 1991; 111: 356-361.
    • (1991) Exp Neurol , vol.111 , pp. 356-361
    • Ormandy, G.C.1    Song, L.2    Jope, R.S.3
  • 40
    • 0025949374 scopus 로고
    • Seizures increase acetylcholine and choline concentrations in rat brain regions
    • Jope RS, Gu X. Seizures increase acetylcholine and choline concentrations in rat brain regions. Neurochem Res 1991; 16: 1219-1226.
    • (1991) Neurochem Res , vol.16 , pp. 1219-1226
    • Jope, R.S.1    Gu, X.2
  • 41
    • 0029559859 scopus 로고
    • Systemic administration of lithium chloride and tacrine but not kainic acid augments citrulline content of rat brain
    • Bagetta G, Rodino P, Paoletti AM, Arabia A, Massoud R, Nistico G. Systemic administration of lithium chloride and tacrine but not kainic acid augments citrulline content of rat brain. Eur J Pharmacol 1995; 294: 341-433.
    • (1995) Eur J Pharmacol , vol.294 , pp. 341-433
    • Bagetta, G.1    Rodino, P.2    Paoletti, A.M.3    Arabia, A.4    Massoud, R.5    Nistico, G.6
  • 42
    • 0026742320 scopus 로고
    • GABA receptor alterations after chronic lithium administration. Comparison with carbamazepine and sodium valproate
    • Motohashi N. GABA receptor alterations after chronic lithium administration. Comparison with carbamazepine and sodium valproate. Prog Neuropsychopharmacol Biol Psychiatry 1992; 16: 571-579.
    • (1992) Prog Neuropsychopharmacol Biol Psychiatry , vol.16 , pp. 571-579
    • Motohashi, N.1
  • 43
    • 0032053979 scopus 로고    scopus 로고
    • Dissimilar effects of lithium and valproic acid on GABA and glutamine concentrations in rat cerebrospinal fluid
    • Vargas C, Tannhauser M, Barros HM. Dissimilar effects of lithium and valproic acid on GABA and glutamine concentrations in rat cerebrospinal fluid. Gen Pharmacol 1998; 30: 601-604.
    • (1998) Gen Pharmacol , vol.30 , pp. 601-604
    • Vargas, C.1    Tannhauser, M.2    Barros, H.M.3
  • 44
    • 0028287225 scopus 로고
    • Lithium potentiates phosphoinositide-linked 5-HT receptor stimulation in vivo
    • Williams NB, Jope RS. Lithium potentiates phosphoinositide-linked 5-HT receptor stimulation in vivo. NeuroReport 1994; 5: 1118-1120.
    • (1994) NeuroReport , vol.5 , pp. 1118-1120
    • Williams, N.B.1    Jope, R.S.2
  • 45
    • 0030220631 scopus 로고    scopus 로고
    • Differential effects of clonidine, lithium and quinine in the forced swimming test in mice for antidepressants; possible roles of serotoninergic systems
    • Bourin M, Hascoet M, Colombel M-C, Redrobe JP, Baker GB. Differential effects of clonidine, lithium and quinine in the forced swimming test in mice for antidepressants; possible roles of serotoninergic systems. Eur Neuropsychopharmacol 1996; 6: 231-236.
    • (1996) Eur Neuropsychopharmacol , vol.6 , pp. 231-236
    • Bourin, M.1    Hascoet, M.2    Colombel, M.-C.3    Redrobe, J.P.4    Baker, G.B.5
  • 46
    • 0030748388 scopus 로고    scopus 로고
    • Regulation of central serotonin transporters by chronic lithium; an autoradiographic study
    • Carli M, Reader TA. Regulation of central serotonin transporters by chronic lithium; an autoradiographic study. Synapse 1997; 27: 83-89.
    • (1997) Synapse , vol.27 , pp. 83-89
    • Carli, M.1    Reader, T.A.2
  • 48
    • 0032029238 scopus 로고    scopus 로고
    • Paradoxical effects of lithium on serotonergic receptor function: An immunocytochemical, behavioral and autoradiographic study
    • Moorman JM, Leslie RA. Paradoxical effects of lithium on serotonergic receptor function: an immunocytochemical, behavioral and autoradiographic study. Neuropharmacology 1998; 37: 357-374.
    • (1998) Neuropharmacology , vol.37 , pp. 357-374
    • Moorman, J.M.1    Leslie, R.A.2
  • 49
    • 0026528044 scopus 로고
    • Lithium and serotonergic neural transmission: A review of pharmacological and biochemical aspects in animal studies
    • Odagaki Y, Koyama T, Yamashita I. Lithium and serotonergic neural transmission: a review of pharmacological and biochemical aspects in animal studies. Lithium 1992; 3: 95-107.
    • (1992) Lithium , vol.3 , pp. 95-107
    • Odagaki, Y.1    Koyama, T.2    Yamashita, I.3
  • 50
    • 0020465411 scopus 로고
    • Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
    • Berridge MJ, Downes CP, Hanley MR. Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J 1982; 206: 587-595.
    • (1982) Biochem J , vol.206 , pp. 587-595
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 51
    • 0027268573 scopus 로고
    • Comparative effect of lithium on the phosphoinositide cycle in rat cerebral cortex, hippocampus, and striatum
    • Jenkinson S, Patel N, Nahorski SR, Challiss RAJ. Comparative effect of lithium on the phosphoinositide cycle in rat cerebral cortex, hippocampus, and striatum. J Neurochem 1993; 61: 1082-1090.
    • (1993) J Neurochem , vol.61 , pp. 1082-1090
    • Jenkinson, S.1    Patel, N.2    Nahorski, S.R.3    Challiss, R.A.J.4
  • 52
    • 0028111809 scopus 로고
    • Differential effects of lithium on muscarinic cholinoceptor-stimulated CMP-phosphatidate accumulation in cerebellar granule cells, CHO-M3 cells, and SH-SY5Y neuroblastoma cells
    • Gray DW, Challiss RAJ, Nahorski SR. Differential effects of lithium on muscarinic cholinoceptor-stimulated CMP-phosphatidate accumulation in cerebellar granule cells, CHO-M3 cells, and SH-SY5Y neuroblastoma cells. J Neurochem 1994; 63: 1354-1360.
    • (1994) J Neurochem , vol.63 , pp. 1354-1360
    • Gray, D.W.1    Challiss, R.A.J.2    Nahorski, S.R.3
  • 53
    • 0028566972 scopus 로고
    • Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant m1 muscarinic receptors
    • Jenkinson S, Nahorski SR, Challiss RAJ. Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant m1 muscarinic receptors. Mol Pharmacol 1994; 46: 1138-1148.
    • (1994) Mol Pharmacol , vol.46 , pp. 1138-1148
    • Jenkinson, S.1    Nahorski, S.R.2    Challiss, R.A.J.3
  • 54
    • 0031930469 scopus 로고    scopus 로고
    • Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture
    • del Rio E, Shinomura T, van der Kaay J, Nicholls DG, Downes CP. Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture. J Neurochem 1998; 70: 1662-1669.
    • (1998) J Neurochem , vol.70 , pp. 1662-1669
    • Del Rio, E.1    Shinomura, T.2    Van Der Kaay, J.3    Nicholls, D.G.4    Downes, C.P.5
  • 55
    • 0032521441 scopus 로고    scopus 로고
    • Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells
    • Batty IH, Currie RA, Downes CP. Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells. Biochem J 1998; 330: 1069-1077.
    • (1998) Biochem J , vol.330 , pp. 1069-1077
    • Batty, I.H.1    Currie, R.A.2    Downes, C.P.3
  • 56
    • 0032570702 scopus 로고    scopus 로고
    • Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells
    • Willars GB, Nahorski SR, Challiss RA. Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. J Biol Chem 1998; 273: 5037-5046.
    • (1998) J Biol Chem , vol.273 , pp. 5037-5046
    • Willars, G.B.1    Nahorski, S.R.2    Challiss, R.A.3
  • 58
    • 0030877331 scopus 로고    scopus 로고
    • Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder
    • Shimon H, Agam G, Belmaker RH, Hyde TM, Kleinman JE. Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder. Am J Psychiatry 1997; 154: 1148-1150.
    • (1997) Am J Psychiatry , vol.154 , pp. 1148-1150
    • Shimon, H.1    Agam, G.2    Belmaker, R.H.3    Hyde, T.M.4    Kleinman, J.E.5
  • 61
    • 0031225466 scopus 로고    scopus 로고
    • Lithium-induced inositol depletion in rat brain after chronic treatment is restricted to the hypothalamus
    • Lubrich B, Patishi Y, Kofman O, Agam G, Berger M Belmaker RH et al. Lithium-induced inositol depletion in rat brain after chronic treatment is restricted to the hypothalamus. Mol Psychiatry 1997; 2: 407-412.
    • (1997) Mol Psychiatry , vol.2 , pp. 407-412
    • Lubrich, B.1    Patishi, Y.2    Kofman, O.3    Agam, G.4    Berger, M.5    Belmaker, R.H.6
  • 62
    • 0032171218 scopus 로고    scopus 로고
    • Behavioral reversal of lithium effects by four inositol isomers correlates perfectly with biochemical effects on the PI cycle: Depletion by chronic lithium of brain inositol is specific to hypothalamus,+ and inositol levels may be abnormal in postmortem brain from bipolar patients
    • Belmaker RH, Agam G, van Calker D, Richards MH, Kofman O. Behavioral reversal of lithium effects by four inositol isomers correlates perfectly with biochemical effects on the PI cycle: depletion by chronic lithium of brain inositol is specific to hypothalamus,+ and inositol levels may be abnormal in postmortem brain from bipolar patients. Neuropsychopharmocology 1998; 19: 220-232.
    • (1998) Neuropsychopharmocology , vol.19 , pp. 220-232
    • Belmaker, R.H.1    Agam, G.2    Van Calker, D.3    Richards, M.H.4    Kofman, O.5
  • 63
    • 0032536715 scopus 로고    scopus 로고
    • Chronic treatment with lithium and pretreatment with excess inositol reduce inositol pool size in astrocytes by different mechanisms
    • Wolfson M, Hertz E, Belmaker RH, Hertz L. Chronic treatment with lithium and pretreatment with excess inositol reduce inositol pool size in astrocytes by different mechanisms. Brain Res 1998; 787: 34-40.
    • (1998) Brain Res , vol.787 , pp. 34-40
    • Wolfson, M.1    Hertz, E.2    Belmaker, R.H.3    Hertz, L.4
  • 64
    • 0023854951 scopus 로고
    • Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex
    • Avissar S, Schreiber G, Danon A, Belmaker RH. Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex, Nature 1988; 331: 440-442.
    • (1988) Nature , vol.331 , pp. 440-442
    • Avissar, S.1    Schreiber, G.2    Danon, A.3    Belmaker, R.H.4
  • 65
    • 0026763345 scopus 로고
    • Chronic: Lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions
    • Song L, Jope RS. Chronic: lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions. J Neurochem 1992; 58: 2200-2206.
    • (1992) J Neurochem , vol.58 , pp. 2200-2206
    • Song, L.1    Jope, R.S.2
  • 67
    • 0026069462 scopus 로고
    • Magnesium reversal of lithium inhibition of beta-adrenergic and muscarinic receptor coupling to G-proteins
    • Avissar S, Murphy DL, Schreiber G. Magnesium reversal of lithium inhibition of beta-adrenergic and muscarinic receptor coupling to G-proteins. Biochem Pharmacol 1991; 41: 171-175.
    • (1991) Biochem Pharmacol , vol.41 , pp. 171-175
    • Avissar, S.1    Murphy, D.L.2    Schreiber, G.3
  • 68
    • 0025039966 scopus 로고
    • The effect of acute and chronic: Lithium treatment on pilocarpine-stimulated phosphoinositide hydrolysis in mouse brain in vivo
    • Whitworth P, Heal DJ, Kendall DA. The effect of acute and chronic: lithium treatment on pilocarpine-stimulated phosphoinositide hydrolysis in mouse brain in vivo. Br J Pharmacol 1990; 101: 39-44.
    • (1990) Br J Pharmacol , vol.101 , pp. 39-44
    • Whitworth, P.1    Heal, D.J.2    Kendall, D.A.3
  • 69
    • 0026597767 scopus 로고
    • Inositol trisphosphate, cyclic AMP and cyclic GMP in rat brain regions after lithium and seizures
    • Jope RS, Song L, Kolasa K. Inositol trisphosphate, cyclic AMP and cyclic GMP in rat brain regions after lithium and seizures. Biol Psychiatry 1992; 31: 505-514.
    • (1992) Biol Psychiatry , vol.31 , pp. 505-514
    • Jope, R.S.1    Song, L.2    Kolasa, K.3
  • 70
    • 0029916799 scopus 로고    scopus 로고
    • Acute or chronic lithium does not effect agonist-stimulated inositol trisphosphate formation in rat brain in vivo
    • Gur E, Lerer B, Newman ME. Acute or chronic lithium does not effect agonist-stimulated inositol trisphosphate formation in rat brain in vivo. Neuroreport 1996; 7: 393-396.
    • (1996) Neuroreport , vol.7 , pp. 393-396
    • Gur, E.1    Lerer, B.2    Newman, M.E.3
  • 71
    • 0027407528 scopus 로고
    • J-muscarinic acetylcholine receptors in cultured cerebellar granule cells
    • J-muscarinic acetylcholine receptors in cultured cerebellar granule cells. Neurochem Int 1993; 22: 395-403.
    • (1993) Neurochem Int , vol.22 , pp. 395-403
    • Gao, X.-M.1    Fukamauchi, F.2    Chuang, D.-M.3
  • 72
    • 0029950633 scopus 로고    scopus 로고
    • The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain
    • Jope RS, Song L, Li PP, Young LT, Kish SJ, Pacheco MA et al. The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain. J Neurochem 1996; 66: 2402-2409.
    • (1996) J Neurochem , vol.66 , pp. 2402-2409
    • Jope, R.S.1    Song, L.2    Li, P.P.3    Young, L.T.4    Kish, S.J.5    Pacheco, M.A.6
  • 77
    • 0029671363 scopus 로고    scopus 로고
    • 2+ uptake into platelets in bipolar affective disorder and controls
    • 2+ uptake into platelets in bipolar affective disorder and controls. Clin Nauropharmacol 1996; 19: 48-51.
    • (1996) Clin Nauropharmacol , vol.19 , pp. 48-51
    • Berk, M.1    Kirchmann, N.H.2    Butkow, N.3
  • 78
    • 0029925565 scopus 로고    scopus 로고
    • i in cultured astrocytes by chronic treatment with a therapeutically relevant lithium concentration
    • i in cultured astrocytes by chronic treatment with a therapeutically relevant lithium concentration. Brain Res 1996; 711: 245-248.
    • (1996) Brain Res , vol.711 , pp. 245-248
    • Chen, Y.1    Hertz, L.2
  • 79
    • 0024397923 scopus 로고
    • Lithium inhibition of protein kinase C activation-induced serotonin release
    • Wang H-Y, Friedman E. Lithium inhibition of protein kinase C activation-induced serotonin release. Psychopharmacology 1989; 99: 213-218.
    • (1989) Psychopharmacology , vol.99 , pp. 213-218
    • Wang, H.-Y.1    Friedman, E.2
  • 80
    • 0025907561 scopus 로고
    • Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation
    • Casebolt TL, Jope RS. Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation. Biol Psychiatry 1991; 29: 233-243.
    • (1991) Biol Psychiatry , vol.29 , pp. 233-243
    • Casebolt, T.L.1    Jope, R.S.2
  • 81
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox RH, Watson DG, Patel J, Ellis J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res 1992; 570: 333-340.
    • (1992) Brain Res , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.2    Patel, J.3    Ellis, J.4
  • 82
    • 0027374231 scopus 로고
    • Lithium modulation of phosphoinositide signaling system in rat cortex: Selective effect on phorbol ester binding
    • Li PP, Sibony D, Green MA, Warsh JJ. Lithium modulation of phosphoinositide signaling system in rat cortex: selective effect on phorbol ester binding. J Neurochem 1993; 61: 1722-1730.
    • (1993) J Neurochem , vol.61 , pp. 1722-1730
    • Li, P.P.1    Sibony, D.2    Green, M.A.3    Warsh, J.J.4
  • 83
    • 0027278902 scopus 로고
    • Altered protein kinase C activity in Lipolar affective disorder, manic episode
    • Friedman E, Wang H-Y, Levinson D, Connell TA, Singh H. Altered protein kinase C activity in Lipolar affective disorder, manic episode. Biol Psychiatry 1993; 33: 520-525.
    • (1993) Biol Psychiatry , vol.33 , pp. 520-525
    • Friedman, E.1    Wang, H.-Y.2    Levinson, D.3    Connell, T.A.4    Singh, H.5
  • 84
    • 0027366278 scopus 로고
    • Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the α isozyme
    • Manji HK, Etcheberrigaray R, Chen G, Olds JL. Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the α isozyme. J Neurochem 1993; 61: 2303-2310.
    • (1993) J Neurochem , vol.61 , pp. 2303-2310
    • Manji, H.K.1    Etcheberrigaray, R.2    Chen, G.3    Olds, J.L.4
  • 85
    • 0033971392 scopus 로고    scopus 로고
    • A preliminary investigation of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania
    • in press
    • Bebchuk JM, Arfken CL, Dolan-Manji S, Murphy J, Manji HK. A preliminary investigation of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania. Arch Gen Psychiatry 1999; (in press).
    • (1999) Arch Gen Psychiatry
    • Bebchuk, J.M.1    Arfken, C.L.2    Dolan-Manji, S.3    Murphy, J.4    Manji, H.K.5
  • 86
    • 0030036555 scopus 로고    scopus 로고
    • Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
    • Watson DG, Lenox RH. Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation. J Neurochem 1996; 67: 767-777.
    • (1996) J Neurochem , vol.67 , pp. 767-777
    • Watson, D.G.1    Lenox, R.H.2
  • 87
    • 10244224044 scopus 로고    scopus 로고
    • Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains
    • Glaser M, Wanaski S, Buser CA, Boguslavsky V, Rashidzada W, Morris A et al. Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains. J Biol Chem 1996; 271: 26187-26193.
    • (1996) J Biol Chem , vol.271 , pp. 26187-26193
    • Glaser, M.1    Wanaski, S.2    Buser, C.A.3    Boguslavsky, V.4    Rashidzada, W.5    Morris, A.6
  • 89
    • 0025799902 scopus 로고
    • Pertussis toxin potentiates seizures induced by pilocarpine, kainic acid and N-methyl-D-aspartate
    • Ormandy GC, Jope RS. Pertussis toxin potentiates seizures induced by pilocarpine, kainic acid and N-methyl-D-aspartate. Brain Res 1991; 553: 51-57.
    • (1991) Brain Res , vol.553 , pp. 51-57
    • Ormandy, G.C.1    Jope, R.S.2
  • 91
    • 0030763699 scopus 로고    scopus 로고
    • Lack of interfering effects of lithium on receptor/G protein coupling in human platelet and rat brain membranes
    • Odagaki Y, Nishi N, Koyama T. Lack of interfering effects of lithium on receptor/G protein coupling in human platelet and rat brain membranes. Biol Psychiatry 1997; 42: 697-703.
    • (1997) Biol Psychiatry , vol.42 , pp. 697-703
    • Odagaki, Y.1    Nishi, N.2    Koyama, T.3
  • 92
    • 0029010738 scopus 로고
    • Effects of chronic lithium treatment on agonist-enhanced extracellular concentrations of cyclic AMP in the dorsal hippocampus of freely moving rats
    • Mork A, Geisler A. Effects of chronic lithium treatment on agonist-enhanced extracellular concentrations of cyclic AMP in the dorsal hippocampus of freely moving rats. J Neurochem 1995; 65: 134-139.
    • (1995) J Neurochem , vol.65 , pp. 134-139
    • Mork, A.1    Geisler, A.2
  • 93
    • 0028089218 scopus 로고
    • Effects of chronic lithium treatment on central dopaminergic receptor systems: G proteins as possible targets
    • Carli M, Anand-Srivastava MB, Molina-Holgado E, Dewar KM, Reader TA. Effects of chronic lithium treatment on central dopaminergic receptor systems: G proteins as possible targets. Neurochem Int 1994; 24: 13-22.
    • (1994) Neurochem Int , vol.24 , pp. 13-22
    • Carli, M.1    Anand-Srivastava, M.B.2    Molina-Holgado, E.3    Dewar, K.M.4    Reader, T.A.5
  • 94
    • 0028934406 scopus 로고
    • Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain
    • Nestler EJ, Terwilliger RZ, Duman RS. Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain. J Neurochem 1995; 64: 2319-2324.
    • (1995) J Neurochem , vol.64 , pp. 2319-2324
    • Nestler, E.J.1    Terwilliger, R.Z.2    Duman, R.S.3
  • 95
    • 0030575523 scopus 로고    scopus 로고
    • Mood stabilizers have differential effects on endogenous ADP ribosylation in C6 glioma cells
    • Young LT, Woods CM. Mood stabilizers have differential effects on endogenous ADP ribosylation in C6 glioma cells. Eur J Pharmacol 1996; 309: 215-218.
    • (1996) Eur J Pharmacol , vol.309 , pp. 215-218
    • Young, L.T.1    Woods, C.M.2
  • 96
    • 0026733192 scopus 로고
    • Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex
    • Guitart X, Nestler EJ. Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex. J Neurochem 1992; 59: 1164-1167.
    • (1992) J Neurochem , vol.59 , pp. 1164-1167
    • Guitart, X.1    Nestler, E.J.2
  • 97
    • 0030975168 scopus 로고    scopus 로고
    • Altered protein phosphorylation in the rat brain following chronic lithium and carbamazepine treatments
    • Jensen JB, Mork A. Altered protein phosphorylation in the rat brain following chronic lithium and carbamazepine treatments. Eur Neuropsychapharmacol 1997; 7: 173-179.
    • (1997) Eur Neuropsychapharmacol , vol.7 , pp. 173-179
    • Jensen, J.B.1    Mork, A.2
  • 98
    • 0031022814 scopus 로고    scopus 로고
    • Differential effects of lithium on platelet protein phosphorylation in bipolar patients and healthy subjects
    • Zanardi R, Racagni G, Smeraldi E, Perez E. Differential effects of lithium on platelet protein phosphorylation in bipolar patients and healthy subjects. Psychopharmacology 1997; 129: 44-47.
    • (1997) Psychopharmacology , vol.129 , pp. 44-47
    • Zanardi, R.1    Racagni, G.2    Smeraldi, E.3    Perez, E.4
  • 99
  • 101
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 1996; 93: 8455-8459.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 102
    • 0015901399 scopus 로고
    • The influence of sodium, potassium and lithium on the response of glycogen synthetase I to insulin and epinephrine in the isolated rat diaphragm
    • Horn RS, Walaas O, Walaas E. The influence of sodium, potassium and lithium on the response of glycogen synthetase I to insulin and epinephrine in the isolated rat diaphragm. Biochim Biophys Acta 1973; 313: 296-309.
    • (1973) Biochim Biophys Acta , vol.313 , pp. 296-309
    • Horn, R.S.1    Walaas, O.2    Walaas, E.3
  • 103
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signaling in intact cells
    • Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signaling in intact cells. Current Biol 1996; 6: 1664-1668.
    • (1996) Current Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 104
    • 0030868557 scopus 로고    scopus 로고
    • Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
    • Hong M, Chen DCR, Klein PS, Lee VMY. Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3. J Biol Chem 1997; 272: 25326-25332.
    • (1997) J Biol Chem , vol.272 , pp. 25326-25332
    • Hong, M.1    Chen, D.C.R.2    Klein, P.S.3    Lee, V.M.Y.4
  • 105
    • 0031567583 scopus 로고    scopus 로고
    • Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
    • Munoz-Montano JR, Moreno FJ, Avila J, Diaz-Nido J. Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett 1997; 411: 183-188.
    • (1997) FEBS Lett , vol.411 , pp. 183-188
    • Munoz-Montano, J.R.1    Moreno, F.J.2    Avila, J.3    Diaz-Nido, J.4
  • 106
    • 0032521599 scopus 로고    scopus 로고
    • Sequential phosphorylation of tau by glycogen synthase kinase-3β and protein kinase A at thr212 and ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation
    • Zheng-Fischhofer Q, Biernet J, Mandelkow E-M, Illenberger S, Godemann R, Mandelkow E. Sequential phosphorylation of tau by glycogen synthase kinase-3β and protein kinase A at thr212 and ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation. Eur J Biochem 1998; 252: 542-552.
    • (1998) Eur J Biochem , vol.252 , pp. 542-552
    • Zheng-Fischhofer, Q.1    Biernet, J.2    Mandelkow, E.-M.3    Illenberger, S.4    Godemann, R.5    Mandelkow, E.6
  • 107
    • 0032490652 scopus 로고    scopus 로고
    • The inter-relationship between selective tau phosphorylation and microlubule association
    • Xie H, Litersky JM, Hartigan JA, Jope RS, Johnson GVW. The inter-relationship between selective tau phosphorylation and microlubule association. Brain Res 1998; 798: 173-183.
    • (1998) Brain Res , vol.798 , pp. 173-183
    • Xie, H.1    Litersky, J.M.2    Hartigan, J.A.3    Jope, R.S.4    Johnson, G.V.W.5
  • 108
    • 0029994754 scopus 로고    scopus 로고
    • Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules
    • Lovestone S, Hartley CL, Pearce J, Anderton BH. Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: the effects on the organization and stability of microtubules. Neuroscience 1996; 73: 1145-1157.
    • (1996) Neuroscience , vol.73 , pp. 1145-1157
    • Lovestone, S.1    Hartley, C.L.2    Pearce, J.3    Anderton, B.H.4
  • 109
    • 0031800971 scopus 로고    scopus 로고
    • Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodeling induced by WNT-7a or lithium
    • Lucas FR, Gould RG, Gordon-Weeks PR, Salinas PC. Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodeling induced by WNT-7a or lithium. J Cell Sci 1998; 111: 1351-1361.
    • (1998) J Cell Sci , vol.111 , pp. 1351-1361
    • Lucas, F.R.1    Gould, R.G.2    Gordon-Weeks, P.R.3    Salinas, P.C.4
  • 110
    • 1642440160 scopus 로고    scopus 로고
    • Implication of cyclin-dependent kinases and glycogen synthase kinase 3 in the phosphorylation of microtubule-associated protein 1B in developing neuronal cells
    • Garcia-Perez J, Avila J, Diaz-Nido J. Implication of cyclin-dependent kinases and glycogen synthase kinase 3 in the phosphorylation of microtubule-associated protein 1B in developing neuronal cells. J Neurosci Res 1998; 52: 445-452.
    • (1998) J Neurosci Res , vol.52 , pp. 445-452
    • Garcia-Perez, J.1    Avila, J.2    Diaz-Nido, J.3
  • 111
    • 0027982102 scopus 로고
    • Evidence that lithium induces a glutamatergic, nitric oxide-mediated response in rat brain
    • Harvey BH, Carstens ME, Taljaard JJF. Evidence that lithium induces a glutamatergic, nitric oxide-mediated response in rat brain. Neurochem Res 1994; 19: 469-474.
    • (1994) Neurochem Res , vol.19 , pp. 469-474
    • Harvey, B.H.1    Carstens, M.E.2    Taljaard, J.J.F.3
  • 112
    • 0028073483 scopus 로고
    • Inhibition by lithium of cyclic GMP formation without inhibition of nitric oxide generation in the mouse neuroblastoma cell (N1E-115)
    • Shintani F, Kanba S, Nakaki T, Nakamura R, Sato K, Yagi G et al. Inhibition by lithium of cyclic GMP formation without inhibition of nitric oxide generation in the mouse neuroblastoma cell (N1E-115). Neuropsychopharmacology 1994; 11: 119-124.
    • (1994) Neuropsychopharmacology , vol.11 , pp. 119-124
    • Shintani, F.1    Kanba, S.2    Nakaki, T.3    Nakamura, R.4    Sato, K.5    Yagi, G.6
  • 114
    • 0031755359 scopus 로고    scopus 로고
    • Potentiation of astroglial nitric oxide synthase type-2 expression by lithium chloride
    • Feinstein DL. Potentiation of astroglial nitric oxide synthase type-2 expression by lithium chloride. J Neurochem 1998; 71: 883-886.
    • (1998) J Neurochem , vol.71 , pp. 883-886
    • Feinstein, D.L.1
  • 117
    • 0024424946 scopus 로고
    • Induction of c-fos and TIS genes in cultured rat astrocytes by neurotransmitters
    • Arenander AT, de Vellis J, Herschman HR. Induction of c-fos and TIS genes in cultured rat astrocytes by neurotransmitters. J Neurosci Res 1989; 24: 107-114.
    • (1989) J Neurosci Res , vol.24 , pp. 107-114
    • Arenander, A.T.1    De Vellis, J.2    Herschman, H.R.3
  • 118
    • 0025283694 scopus 로고
    • Lithium augments fos protooncugene expression in PC12 pheochromocytoma cells: Implications for therapeutic action
    • Kalasapudi VD, Sheftel G, Divish MM, Papolos DF, Lachman HM. Lithium augments fos protooncugene expression in PC12 pheochromocytoma cells: implications for therapeutic action. Brain Res 1990; 521: 47-54.
    • (1990) Brain Res , vol.521 , pp. 47-54
    • Kalasapudi, V.D.1    Sheftel, G.2    Divish, M.M.3    Papolos, D.F.4    Lachman, H.M.5
  • 119
    • 0026065035 scopus 로고
    • Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: Model for its antimanic action
    • Divish MM, Sheftel G, Boyle A, Kalasapudi VD, Papolos DF, Lachman HM. Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: model for its antimanic action. J Neurosci Res 1991; 28: 40-48.
    • (1991) J Neurosci Res , vol.28 , pp. 40-48
    • Divish, M.M.1    Sheftel, G.2    Boyle, A.3    Kalasapudi, V.D.4    Papolos, D.F.5    Lachman, H.M.6
  • 120
    • 0025879163 scopus 로고
    • Lithium augments pilocarpine-induced fos gene expression in rat brain
    • Weiner ED, Kalasapudi VD, Papolos DF, Lachman HM. Lithium augments pilocarpine-induced fos gene expression in rat brain. Brain Res 1991; 553: 117-122.
    • (1991) Brain Res , vol.553 , pp. 117-122
    • Weiner, E.D.1    Kalasapudi, V.D.2    Papolos, D.F.3    Lachman, H.M.4
  • 121
    • 0028240703 scopus 로고
    • Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine
    • Williams MB, Jope RS. Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine. Mol Brain Res 1994; 25: 80-89.
    • (1994) Mol Brain Res , vol.25 , pp. 80-89
    • Williams, M.B.1    Jope, R.S.2
  • 123
    • 0029953493 scopus 로고    scopus 로고
    • Characterization of inhibition by chronic lithium treatment with lithium ion on nerve growth factor-induced neuronal differentiation of rat PC12 pheochromocytoma cells
    • Harada H, Sugiyama T, Suketa Y. Characterization of inhibition by chronic lithium treatment with lithium ion on nerve growth factor-induced neuronal differentiation of rat PC12 pheochromocytoma cells. J Toxicol Environ Health 1996; 49: 197-206.
    • (1996) J Toxicol Environ Health , vol.49 , pp. 197-206
    • Harada, H.1    Sugiyama, T.2    Suketa, Y.3
  • 124
    • 0030910190 scopus 로고    scopus 로고
    • Basal and stimulated c-fos mRNA expression in the rat brain: Effect of chronic dietary lithium
    • Miller JC, Mathe AA. Basal and stimulated c-fos mRNA expression in the rat brain: effect of chronic dietary lithium. Nourapsychopharmacology 1997; 16: 408-418.
    • (1997) Nourapsychopharmacology , vol.16 , pp. 408-418
    • Miller, J.C.1    Mathe, A.A.2
  • 125
    • 0030954414 scopus 로고    scopus 로고
    • Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cells
    • Unlap MT, Jope RS. Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cells. Neuropsychopharmacology 1997; 17: 12-17.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 12-17
    • Unlap, M.T.1    Jope, R.S.2
  • 126
    • 0030723121 scopus 로고    scopus 로고
    • Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain
    • Ozaki N, Chuang D-M. Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J Neurochem 1997; 69: 2336-2344.
    • (1997) J Neurochem , vol.69 , pp. 2336-2344
    • Ozaki, N.1    Chuang, D.-M.2
  • 127
    • 0032567688 scopus 로고    scopus 로고
    • Lithium inhibits the reverse tolerance and the c-Fos expression induced by methamphetamine in mice
    • Namima M, Sugihara K, Okamoto K. Lithium inhibits the reverse tolerance and the c-Fos expression induced by methamphetamine in mice. Brain Res 1998; 782: 83-90.
    • (1998) Brain Res , vol.782 , pp. 83-90
    • Namima, M.1    Sugihara, K.2    Okamoto, K.3
  • 128
    • 0032528112 scopus 로고    scopus 로고
    • Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells
    • Asghari V, Wang JF, Reiach JS, Young LT. Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells. Mol Brain Res 1998; 58: 95-102.
    • (1998) Mol Brain Res , vol.58 , pp. 95-102
    • Asghari, V.1    Wang, J.F.2    Reiach, J.S.3    Young, L.T.4
  • 129
    • 0029622424 scopus 로고
    • Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: Modulation by lithium
    • Williams MB, Jope RS. Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: modulation by lithium. Psychopharmacology 1995; 122: 363-368.
    • (1995) Psychopharmacology , vol.122 , pp. 363-368
    • Williams, M.B.1    Jope, R.S.2
  • 130
    • 0030694569 scopus 로고    scopus 로고
    • AP-1 and NF-KB stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium
    • Jope RS, Song L. AP-1 and NF-KB stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium. Mol Brain Res 1997; 50: 171-180.
    • (1997) Mol Brain Res , vol.50 , pp. 171-180
    • Jope, R.S.1    Song, L.2
  • 131
    • 0032527821 scopus 로고    scopus 로고
    • Lithium stimulates gene expression through the AP-1 transcription factor pathway
    • Yuan P-X, Chen G, Huang L-D, Manji HK. Lithium stimulates gene expression through the AP-1 transcription factor pathway. Mol Brain Res 1998; 58: 225-230.
    • (1998) Mol Brain Res , vol.58 , pp. 225-230
    • Yuan, P.-X.1    Chen, G.2    Huang, L.-D.3    Manji, H.K.4
  • 132
    • 0032953393 scopus 로고    scopus 로고
    • Cyclic AMP responsive element binding protein phosphorylation and DNA binding is decreased by chronic lithium but not valproate treatment of SH-SY5Y neuroblastoma cells
    • in press
    • Wang JF, Asghari V, Rockel C, Young LT. Cyclic AMP responsive element binding protein phosphorylation and DNA binding is decreased by chronic lithium but not valproate treatment of SH-SY5Y neuroblastoma cells. Neuroscience 1999; (in press).
    • (1999) Neuroscience
    • Wang, J.F.1    Asghari, V.2    Rockel, C.3    Young, L.T.4
  • 133
    • 0030582086 scopus 로고    scopus 로고
    • Hippocampal and cortical G protein Gsα, Goα, Gi2α mRNA expression after electroconvulsive shock or lithium treatment
    • McGowan S, Eastwood SL, Mead A, Burnet PWJ, Smith C, Flanigan TP et al. Hippocampal and cortical G protein Gsα, Goα, Gi2α mRNA expression after electroconvulsive shock or lithium treatment. Eur J Pharmacol 1996; 306: 249-255.
    • (1996) Eur J Pharmacol , vol.306 , pp. 249-255
    • McGowan, S.1    Eastwood, S.L.2    Mead, A.3    Burnet, P.W.J.4    Smith, C.5    Flanigan, T.P.6
  • 134
    • 0030666416 scopus 로고    scopus 로고
    • Effects of subchronic administration of antidepressants and anxiolytics on levels of the α subunits of G proteins in the rat brain
    • Dwivedi Y, Pandey GN. Effects of subchronic administration of antidepressants and anxiolytics on levels of the α subunits of G proteins in the rat brain. J Neural Trans 1997; 104: 747-760.
    • (1997) J Neural Trans , vol.104 , pp. 747-760
    • Dwivedi, Y.1    Pandey, G.N.2
  • 135
    • 0032484542 scopus 로고    scopus 로고
    • Selective effects of long-term lithium and carbamazepine administration on G-protein subunit expression in rat brain
    • Jakobsen SN, Wiborg O. Selective effects of long-term lithium and carbamazepine administration on G-protein subunit expression in rat brain. Brain Res 1998; 780: 46-55.
    • (1998) Brain Res , vol.780 , pp. 46-55
    • Jakobsen, S.N.1    Wiborg, O.2
  • 136
    • 0027941314 scopus 로고
    • Chronic administration of lithium chloride increases immunodetectable glial fibrillary acidic protein in the rat hippocampus
    • Rocha E, Rodnight R. Chronic administration of lithium chloride increases immunodetectable glial fibrillary acidic protein in the rat hippocampus. J Neurochem 1994; 63: 1582-1584.
    • (1994) J Neurochem , vol.63 , pp. 1582-1584
    • Rocha, E.1    Rodnight, R.2
  • 137
    • 0029819080 scopus 로고    scopus 로고
    • Brain polyamine stress response: Recurrence after repetitive stressor and inhibition by lithium
    • Gilad GM, Gilad VH. Brain polyamine stress response: recurrence after repetitive stressor and inhibition by lithium. J Neurochem 1996; 67: 1992-1996.
    • (1996) J Neurochem , vol.67 , pp. 1992-1996
    • Gilad, G.M.1    Gilad, V.H.2
  • 138
    • 0028032868 scopus 로고
    • Synergistic induction of neurotensin gene transcription in PC12 cells parallels changes in AP-1 activity
    • Bullock BP, McNeil GP, Dobner PR. Synergistic induction of neurotensin gene transcription in PC12 cells parallels changes in AP-1 activity. Mol Brain Res 1994; 27: 232-242.
    • (1994) Mol Brain Res , vol.27 , pp. 232-242
    • Bullock, B.P.1    McNeil, G.P.2    Dobner, P.R.3
  • 139
    • 0031574346 scopus 로고    scopus 로고
    • Lithium increases melanin-concentrating hormone mRNA stability and inhibits tyrosine hydroxylase gene expression in PC12 cells
    • Presse F, Cardona B, Borsu L, Nahon J-L. Lithium increases melanin-concentrating hormone mRNA stability and inhibits tyrosine hydroxylase gene expression in PC12 cells. Mol Brain Res 1997; 52: 270-283.
    • (1997) Mol Brain Res , vol.52 , pp. 270-283
    • Presse, F.1    Cardona, B.2    Borsu, L.3    Nahon, J.-L.4
  • 140
    • 0031930118 scopus 로고    scopus 로고
    • Lithium increases tyrosine hydroxylase levels both in vivo and in vitro
    • Chen G, Yuan P-X, Jiang Y-M, Huang L-D, Manji HK, Lithium increases tyrosine hydroxylase levels both in vivo and in vitro. J Neurochem 1998; 70: 1768-1771.
    • (1998) J Neurochem , vol.70 , pp. 1768-1771
    • Chen, G.1    Yuan, P.-X.2    Jiang, Y.-M.3    Huang, L.-D.4    Manji, H.K.5
  • 141
    • 0029025586 scopus 로고
    • Region-specific effects of chronic lithium administration on neuropeptide Y and somatostatin mRNA expression in the rat brain
    • Zachrisson O, Mathe AA, Stenfors C, Lindefurs N. Region-specific effects of chronic lithium administration on neuropeptide Y and somatostatin mRNA expression in the rat brain. Neurosci Lett 1995; 194: 89-92.
    • (1995) Neurosci Lett , vol.194 , pp. 89-92
    • Zachrisson, O.1    Mathe, A.A.2    Stenfors, C.3    Lindefurs, N.4
  • 142
    • 0030608469 scopus 로고    scopus 로고
    • Effects of chronic lithium and electroconvulsive stimuli on cholecystokinin mRNA expression in the rat brain
    • Zachrisson O, Mathe AA, Lindefors N. Effects of chronic lithium and electroconvulsive stimuli on cholecystokinin mRNA expression in the rat brain. Mol Brain Res 1996; 43: 347-350.
    • (1996) Mol Brain Res , vol.43 , pp. 347-350
    • Zachrisson, O.1    Mathe, A.A.2    Lindefors, N.3
  • 143
    • 0029896911 scopus 로고    scopus 로고
    • Differential display PCR reveals increased expression of 2′,3′ cyclic nucleotide 3′-phosphodiesterase by lithium
    • Wang JF, Young LT. Differential display PCR reveals increased expression of 2′,3′ cyclic nucleotide 3′-phosphodiesterase by lithium. FEBS Lett 1996; 386: 225-229.
    • (1996) FEBS Lett , vol.386 , pp. 225-229
    • Wang, J.F.1    Young, L.T.2
  • 144
    • 0028966044 scopus 로고
    • The Na, K-ATPase hypothesis for bipolar disorder
    • El-Mallakh RS, Wyatt RJ. The Na, K-ATPase hypothesis for bipolar disorder. Biol Psychiatry 1995; 37: 235-244.
    • (1995) Biol Psychiatry , vol.37 , pp. 235-244
    • El-Mallakh, R.S.1    Wyatt, R.J.2
  • 145
    • 0029041009 scopus 로고
    • The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: High triiodothyronine serum concentrations are correlated to the prophylactic efficacy
    • Baumgartner A, von Stuckrad M, Muller-Oerlinghausen B, Graf K-J, Kurten 1. The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: high triiodothyronine serum concentrations are correlated to the prophylactic efficacy. J Affect Dis 1995; 34: 211-218.
    • (1995) J Affect Dis , vol.34 , pp. 211-218
    • Baumgartner, A.1    Von Stuckrad, M.2    Muller-Oerlinghausen, B.3    Graf, K.-J.4    Kurten, I.5
  • 147
    • 0028888777 scopus 로고
    • Renal, thyroid and parathyroid function during lithium treatment: Laboratory tests in 207 people treated for 1-30 years
    • Kallner G, Petterson KG. Renal, thyroid and parathyroid function during lithium treatment: laboratory tests in 207 people treated for 1-30 years. Acta Psychiatr Scand 1995; 91: 48-51.
    • (1995) Acta Psychiatr Scand , vol.91 , pp. 48-51
    • Kallner, G.1    Petterson, K.G.2
  • 148
    • 0028004567 scopus 로고
    • Effect of lithium carbonate on activity level and circadian period in different strains of rats
    • Hafen T, Wollnik F. Effect of lithium carbonate on activity level and circadian period in different strains of rats. Pharmarol Biochem Behavior 1994; 49: 975-983.
    • (1994) Pharmarol Biochem Behavior , vol.49 , pp. 975-983
    • Hafen, T.1    Wollnik, F.2


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