Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons

FASEB Journal

Volumn 15, Issue 1, 2001, Pages 134-144

  See V ^a   Boutillier, A L ^a   Bito, H ^a   Loeffler, J P ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Calcium channels; cAMP responsive element binding protein (CREB); CPP32 caspase 3; Gene transfer; Nuclear condensation

Indexed keywords

CALCIUM CHANNEL; CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NIFEDIPINE; OMEGA CONOTOXIN; POTASSIUM; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE (CALCIUM,CALMODULIN) IV; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE OVEREXPRESSION; GENE TRANSFER; GRANULE CELL; IMMUNOCYTOCHEMISTRY; MOUSE; NEUROPROTECTION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM CHANNELS, N-TYPE; CALCIUM SIGNALING; CASPASE 3; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIHYDROPYRIDINES; GENES, DOMINANT; MICE; MODELS, BIOLOGICAL; MUTATION; NEURONS; NEUROPROTECTIVE AGENTS; NIFEDIPINE; PHOSPHORYLATION; POTASSIUM; PROTEIN PROCESSING, POST-TRANSLATIONAL;

ANIMALIA;

EID: 0035175495     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0106com     Document Type: Article

References (50)

1. Apoptosis is induced by B-amyloid in cultured central nervous system neurons
2. Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
3. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
4. Induction od apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
5. Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
6. Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons
7. PACAP type I receptor activation promotes cerebellar neurons survival through the cAMP/PKA signalling pathway
8. Mechanisms and functions of cell death
9. Protease activation during apoptosis: Death by a thousand cuts?
10. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
11. Human ICE/CED-3 protease nomenclature
12. Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis
13. The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells
14. Death-signalling cascade in mouse cerebellar granule neurons
15. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
16. Depolarization regulates cyclin D1 degradation and neuronal apoptosis: A hypothesis about the role of the ubiquitin/proteasome signalling pathway
17. 2+/calmodulin-dependent protein kinase activity
18. 2+/calmodulin-dependent protein kinases
19. The Ca-calmodulin-dependent protein kinase cascade
20. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB
21. 2+-dependent routes to ras: Mechanisms for neuronal survival differentiation and plasticity
22. 2+-dependent regulation in neuronal gene expression
23. 2+/calmodulin-dependent protein kinases within the nucleus
24. 2+- and stimulus duration-dependent switch for hippocampal gene expression
25. Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels
26. 2+ influx regulates BDNF transcription by a CREB transcription factor-dependent mechanism
27. Identification of a signaling pathway involved in calcium regulation of BDNF expression
28. 2+/calmodulin-dependent protein kinase IV
29. A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death
30. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity
31. A fast and simple method to introduce multiple distant point mutations (Treads Pharmacol. Sci. Online T40068)
32. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
33. Ceramide induces apoptosis in cultured mesencephalic neurons
34. Pituitary adenylyl cyclase-activating polypeptide and nerve growth factor use the proteasome to rescue nerve growth factor-deprived sympathetic neurons cultured from chick embryos
35. Susceptibility of cerebellar granule neurons derived from Bcl-2-deficient and transgenic mice to cell death
36. Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis
37. CREB: A major mediator of neuronal neurotrophin responses
38. Fine tuning of calcium entry into neurons regulates adenosine 3′,5′-monophosphate-dependent transcription by several distinct mechanisms
39. Activity-dependent survival and enhanced turnover of calcium in cultured rat cerebellar granule neurons
40. 2+
41. Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
42. Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP
43. Calmodulin-dependent protein kinase II mediates signal transduction in apoptosis
44. Excitotoxicity affects membrane potential and calmodulin kinase II activity in cultured rat cortical neurons
45. Recent advances oh neuronal caspases in development and neurodegeneration
46. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression
47. 2+ channel currents in rat cerebellar granule neurons
48. Critical dependence of CREB phosphorylation on L-type calcium channels supports a selective response to EPSPs rather than action potentials
49. Attenuation of the seizure-induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin-dependent protein kinases