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Volumn 379, Issue 1, 2009, Pages 145-150

Bim is reversibly phosphorylated but plays a limited role in paclitaxel cytotoxicity of breast cancer cell lines

Author keywords

Apoptosis; BH3; Bim; Paclitaxel; Taxanes

Indexed keywords

BIM PROTEIN; PACLITAXEL;

EID: 58149288060     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.025     Document Type: Article
Times cited : (19)

References (30)
  • 1
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan M.A., and Wilson L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4 (2004) 253-265
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 2
    • 0034212385 scopus 로고    scopus 로고
    • Paclitaxel-induced cell death: where the cell cycle and apoptosis come together
    • Wang T.H., Wang H.S., and Soong Y.K. Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 88 (2000) 2619-2628
    • (2000) Cancer , vol.88 , pp. 2619-2628
    • Wang, T.H.1    Wang, H.S.2    Soong, Y.K.3
  • 3
    • 20044379059 scopus 로고    scopus 로고
    • Review: tubulin function action of antitubulin drugs, and new drug development
    • Pellegrini F., and Budman D.R. Review: tubulin function action of antitubulin drugs, and new drug development. Cancer Invest. 23 (2005) 264-273
    • (2005) Cancer Invest. , vol.23 , pp. 264-273
    • Pellegrini, F.1    Budman, D.R.2
  • 4
    • 0029328641 scopus 로고
    • Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway
    • Woods C.M., Zhu J., McQueney P.A., Bollag D., and Lazarides E. Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway. Mol. Med. 1 (1995) 506-526
    • (1995) Mol. Med. , vol.1 , pp. 506-526
    • Woods, C.M.1    Zhu, J.2    McQueney, P.A.3    Bollag, D.4    Lazarides, E.5
  • 5
    • 0030020158 scopus 로고    scopus 로고
    • Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
    • Jordan M.A., Wendell K., Gardiner S., Derry W.B., Copp H., and Wilson L. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res. 56 (1996) 816-825
    • (1996) Cancer Res. , vol.56 , pp. 816-825
    • Jordan, M.A.1    Wendell, K.2    Gardiner, S.3    Derry, W.B.4    Copp, H.5    Wilson, L.6
  • 6
    • 0032529464 scopus 로고    scopus 로고
    • Mechanisms of taxol-induced cell death are concentration dependent
    • Torres K., and Horwitz S.B. Mechanisms of taxol-induced cell death are concentration dependent. Cancer Res. 58 (1998) 3620-3626
    • (1998) Cancer Res. , vol.58 , pp. 3620-3626
    • Torres, K.1    Horwitz, S.B.2
  • 7
    • 27544446991 scopus 로고    scopus 로고
    • Life in the balance. How BH3-only proteins induce apoptosis
    • Willis S.N., and Adams J.M. Life in the balance. How BH3-only proteins induce apoptosis. Curr. Opin. Cell Biol. 17 (2005) 617-625
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 617-625
    • Willis, S.N.1    Adams, J.M.2
  • 8
    • 0037089068 scopus 로고    scopus 로고
    • BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
    • Bouillet P., and Strasser A. BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J. Cell Sci. 115 (2002) 1567-1574
    • (2002) J. Cell Sci. , vol.115 , pp. 1567-1574
    • Bouillet, P.1    Strasser, A.2
  • 9
    • 58149288697 scopus 로고    scopus 로고
    • Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death
    • Li Z., Zhang J., Liu Z., Woo C.W., and Thiele C.J. Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death. Cell Death Differ. (2006)
    • (2006) Cell Death Differ.
    • Li, Z.1    Zhang, J.2    Liu, Z.3    Woo, C.W.4    Thiele, C.J.5
  • 11
    • 14944349359 scopus 로고    scopus 로고
    • Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim
    • Li R., Moudgil T., Ross H.J., and Hu H.M. Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. Cell Death Differ. 12 (2005) 292-303
    • (2005) Cell Death Differ. , vol.12 , pp. 292-303
    • Li, R.1    Moudgil, T.2    Ross, H.J.3    Hu, H.M.4
  • 14
    • 33846219461 scopus 로고    scopus 로고
    • Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death
    • Li Z., Zhang J., Liu Z., Woo C.W., and Thiele C.J. Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death. Cell Death Differ. 14 (2007) 318-326
    • (2007) Cell Death Differ. , vol.14 , pp. 318-326
    • Li, Z.1    Zhang, J.2    Liu, Z.3    Woo, C.W.4    Thiele, C.J.5
  • 15
    • 23044514254 scopus 로고    scopus 로고
    • Regulatory phosphorylation of Bim: sorting out the ERK from the JNK
    • Ley R., Ewings K.E., Hadfield K., and Cook S.J. Regulatory phosphorylation of Bim: sorting out the ERK from the JNK. Cell Death Differ. 12 (2005) 1008-1014
    • (2005) Cell Death Differ. , vol.12 , pp. 1008-1014
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3    Cook, S.J.4
  • 16
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath H., and Strasser A. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ. 9 (2002) 505-512
    • (2002) Cell Death Differ. , vol.9 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 18
    • 1542275411 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1/2 are serum-stimulated Bim(EL) kinases That bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover.
    • Ley R., Ewings K.E., Hadfield K., Howes E., Balmanno K., and Cook S.J. Extracellular signal-regulated kinases 1/2 are serum-stimulated Bim(EL) kinases That bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. J. Biol. Chem. 279 (2004) 8837-8847
    • (2004) J. Biol. Chem. , vol.279 , pp. 8837-8847
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3    Howes, E.4    Balmanno, K.5    Cook, S.J.6
  • 19
    • 0242521470 scopus 로고    scopus 로고
    • Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
    • Luciano F., Jacquel A., Colosetti P., Herrant M., Cagnol S., Pages G., and Auberger P. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 22 (2003) 6785-6793
    • (2003) Oncogene , vol.22 , pp. 6785-6793
    • Luciano, F.1    Jacquel, A.2    Colosetti, P.3    Herrant, M.4    Cagnol, S.5    Pages, G.6    Auberger, P.7
  • 20
    • 0032520944 scopus 로고    scopus 로고
    • Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism
    • Derry W.B., Wilson L., and Jordan M.A. Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism. Cancer Res. 58 (1998) 1177-1184
    • (1998) Cancer Res. , vol.58 , pp. 1177-1184
    • Derry, W.B.1    Wilson, L.2    Jordan, M.A.3
  • 21
    • 0032883001 scopus 로고    scopus 로고
    • Molecular effects of paclitaxel: myths and reality (a critical review)
    • Blagosklonny M.V., and Fojo T. Molecular effects of paclitaxel: myths and reality (a critical review). Int. J. Cancer 83 (1999) 151-156
    • (1999) Int. J. Cancer , vol.83 , pp. 151-156
    • Blagosklonny, M.V.1    Fojo, T.2
  • 23
    • 0035499794 scopus 로고    scopus 로고
    • A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines
    • Blajeski A.L., Kottke T.J., and Kaufmann S.H. A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines. Exp. Cell Res. 270 (2001) 277-288
    • (2001) Exp. Cell Res. , vol.270 , pp. 277-288
    • Blajeski, A.L.1    Kottke, T.J.2    Kaufmann, S.H.3
  • 24
    • 33846172672 scopus 로고    scopus 로고
    • An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis
    • Tao W., South V.J., Diehl R.E., Davide J.P., Sepp-Lorenzino L., Fraley M.E., Arrington K.L., and Lobell R.B. An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis. Mol. Cell. Biol. 27 (2007) 689-698
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 689-698
    • Tao, W.1    South, V.J.2    Diehl, R.E.3    Davide, J.P.4    Sepp-Lorenzino, L.5    Fraley, M.E.6    Arrington, K.L.7    Lobell, R.B.8
  • 25
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H., Huang D.C., O'Reilly L.A., King S.M., and Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol. Cell 3 (1999) 287-296
    • (1999) Mol. Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 27
    • 5444234359 scopus 로고    scopus 로고
    • Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
    • Becker E.B., Howell J., Kodama Y., Barker P.A., and Bonni A. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J. Neurosci. 24 (2004) 8762-8770
    • (2004) J. Neurosci. , vol.24 , pp. 8762-8770
    • Becker, E.B.1    Howell, J.2    Kodama, Y.3    Barker, P.A.4    Bonni, A.5
  • 28
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein Bim
    • Ley R., Balmanno K., Hadfield K., Weston C., and Cook S.J. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein Bim. J. Biol. Chem. 278 (2003) 18811-18816
    • (2003) J. Biol. Chem. , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 29
    • 0023239937 scopus 로고
    • Biological differences among MCF-7 human breast cancer cell lines from different laboratories
    • Osborne C.K., Hobbs K., and Trent J.M. Biological differences among MCF-7 human breast cancer cell lines from different laboratories. Breast Cancer Res. Treat. 9 (1987) 111-121
    • (1987) Breast Cancer Res. Treat. , vol.9 , pp. 111-121
    • Osborne, C.K.1    Hobbs, K.2    Trent, J.M.3
  • 30
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Janicke R.U., Sprengart M.L., Wati M.R., and Porter A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273 (1998) 9357-9360
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.