The structure of XIAP BIR2: Understanding the selectivity of the BIR domains

Acta Crystallographica Section D: Biological Crystallography

Volumn 69, Issue 9, 2013, Pages 1717-1725

  Lukacs, Christine ^a   Belunis, Charles ^a   Crowther, Robert ^a   Danho, Waleed ^b   Gao, Lin ^a   Goggin, Barry ^c   Janson, Cheryl A ^a   Li, Shirley ^a   Remiszewski, Stacy ^b   Schutt, Andrew ^c   Thakur, Manish K ^d   Singh, Saroj K ^d   Swaminathan, Srinivasan ^d   Pandey, Rajat ^d   Tyagi, Rajiv ^d   Gosu, Ramachandraiah ^d   Kamath, Ajith V ^d   Kuglstatter, Andreas ^a  

^a Discovery Technologies   (United States)

^b F Hoffmann La Roche   (United States)

^c Discovery Oncology   (United States)

^d JUBILANT BIOSYS LTD   (India)

Author keywords

apoptosis; AVPI; BIR domains; caspases; extrinsic pathway; inhibitor of apoptosis; peptide complex; SMAC; XIAP

Indexed keywords

APOPROTEIN; CASPASE; CASPASE 3; CASPASE INHIBITOR; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS, NUCLEOPOLYHEDROVIRUS; OLIGOPEPTIDE; VIRUS PROTEIN; X LINKED INHIBITOR OF APOPTOSIS;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; AVPI; BIR DOMAINS; CHEMISTRY; EXTRINSIC PATHWAY; GENETICS; HUMAN; INHIBITOR OF APOPTOSIS; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; PEPTIDE COMPLEX; POLYHEDROSIS VIRUS; PROTEIN ANALYSIS; PROTEIN TERTIARY STRUCTURE; SMAC; X RAY CRYSTALLOGRAPHY; XIAP;

APOPTOSIS; AVPI; BIR DOMAINS; CASPASES; EXTRINSIC PATHWAY; INHIBITOR OF APOPTOSIS; PEPTIDE COMPLEX; SMAC; XIAP;

AMINO ACID SEQUENCE; APOPROTEINS; APOPTOSIS; CASPASE 3; CASPASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NUCLEOPOLYHEDROVIRUS; OLIGOPEPTIDES; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84883583426     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444913016284     Document Type: Article

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