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Volumn 8, Issue 5, 2013, Pages 529-554

In vivo astrocytic Ca2+ signaling in health and brain disorders

Author keywords

Alzheimers disease; G protein coupled receptors; in vivo imaging; intercellular Ca2+ waves; IP3 receptor; molecular genetics; photothrombosis; spontaneous Ca2+ signaling; status epilepticus; traumatic brain injury; two photon microscopy

Indexed keywords

CALCIUM; G PROTEIN COUPLED RECEPTOR; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR; RETROVIRUS VECTOR;

EID: 84883316355     PISSN: 14796708     EISSN: 17486971     Source Type: Journal    
DOI: 10.2217/fnl.13.38     Document Type: Review
Times cited : (16)

References (206)
  • 1
    • 52049094570 scopus 로고    scopus 로고
    • What is the role of astrocyte calcium in neurophysiology
    • Agulhon C, Petravicz J, McMullen AB et al. What is the role of astrocyte calcium in neurophysiology Neuron 59(6), 932-946 (2008).
    • (2008) Neuron , vol.59 , Issue.6 , pp. 932-946
    • Agulhon, C.1    Petravicz, J.2    McMullen, A.B.3
  • 2
    • 55049084760 scopus 로고    scopus 로고
    • The mystery and magic of glia: A perspective on their roles in health and disease
    • Barres BA. The mystery and magic of glia: A perspective on their roles in health and disease. Neuron 60(3), 430-440 (2008).
    • (2008) Neuron , vol.60 , Issue.3 , pp. 430-440
    • Barres, B.A.1
  • 3
    • 0035287432 scopus 로고    scopus 로고
    • Glia: Listening and talking to the synapse
    • Haydon PG. Glia: Listening and talking to the synapse. Nat. Rev. Neurosci. 2(3), 185-193 (2001).
    • (2001) Nat. Rev. Neurosci. , vol.2 , Issue.3 , pp. 185-193
    • Haydon, P.G.1
  • 4
    • 35448989687 scopus 로고    scopus 로고
    • Conditional knock-out of kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation
    • Djukic B, Casper KB, Philpot BD, Chin LS, McCarthy KD. Conditional knock-out of kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J. Neurosci. 27(42), 11354-11365 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.42 , pp. 11354-11365
    • Djukic, B.1    Casper, K.B.2    Philpot, B.D.3    Chin, L.S.4    McCarthy, K.D.5
  • 5
    • 2942575981 scopus 로고    scopus 로고
    • Glutamate transporters bring competition to the synapse
    • Huang YH, Bergles DE, Huang YH, Bergles DE. Glutamate transporters bring competition to the synapse. Curr. Opin. Neurobiol. 14(3), 346-352 (2004).
    • (2004) Curr. Opin. Neurobiol. , vol.14 , Issue.3 , pp. 346-352
    • Huang, Y.H.1    De, B.2    Huang, Y.H.3    Bergles, D.E.4
  • 7
    • 0025138986 scopus 로고
    • Glutamate induces calcium waves in cultured astrocytes: Long-range glial signaling
    • Cornell-Bell AH, Finkbeiner SM, Cooper MS, Smith SJ. Glutamate induces calcium waves in cultured astrocytes: Long-range glial signaling. Science 247(4941), 470-473 (1990).
    • (1990) Science , vol.247 , Issue.4941 , pp. 470-473
    • Cornell-Bell, A.H.1    Finkbeiner, S.M.2    Cooper, M.S.3    Smith, S.J.4
  • 8
    • 35148871293 scopus 로고    scopus 로고
    • Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus
    • First paper showing enhanced astrocytic Ca2+ signaling in vivo and the role of mGluR5 in neuroprotection in epilepsy.
    • Ding S, Fellin T, Zhu Y et al. Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus. J. Neurosci. 27(40), 10674-10684 (2007). First paper showing enhanced astrocytic Ca2+ signaling in vivo and the role of mGluR5 in neuroprotection in epilepsy.
    • (2007) J. Neurosci. , vol.27 , Issue.40 , pp. 10674-10684
    • Ding, S.1    Fellin, T.2    Zhu, Y.3
  • 9
    • 4444320120 scopus 로고    scopus 로고
    • Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors
    • Fellin T, Pascual O, Gobbo S, Pozzan T, Haydon PG, Carmignoto G. Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 43(5), 729-743 (2004).
    • (2004) Neuron , vol.43 , Issue.5 , pp. 729-743
    • Fellin, T.1    Pascual, O.2    Gobbo, S.3    Pozzan, T.4    Haydon, P.G.5    Carmignoto, G.6
  • 10
    • 84872165563 scopus 로고    scopus 로고
    • Glutamate-dependent neuroglial calcium signaling differs between young and adult brain
    • Sun W, McConnell E, Pare JF et al. Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. Science 339(6116), 197-200 (2013).
    • (2013) Science , vol.339 , Issue.6116 , pp. 197-200
    • Sun, W.1    McConnell, E.2    Pare, J.F.3
  • 11
    • 66249130054 scopus 로고    scopus 로고
    • Photothrombosis ischemia stimulates a sustained astrocytic Ca2+ signaling in vivo
    • First paper to demonstrate that astrocytes exhibit intercellular Ca2+ waves in vivo after ischemia.
    • Ding S, Wang T, Cui W et al. Photothrombosis ischemia stimulates a sustained astrocytic Ca2+ signaling in vivo. Glia 57(7), 767-776 (2009). First paper to demonstrate that astrocytes exhibit intercellular Ca2+ waves in vivo after ischemia.
    • (2009) Glia , vol.57 , Issue.7 , pp. 767-776
    • Ding, S.1    Wang, T.2    Cui, W.3
  • 12
    • 84869217593 scopus 로고    scopus 로고
    • General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex
    • Thrane AS, Rangroo Thrane V, Zeppenfeld D et al. General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex. Proc. Natl Acad. Sci. USA 109(46), 18974-18979 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.46 , pp. 18974-18979
    • Thrane, A.S.1    Rangroo Thrane, V.2    Zeppenfeld, D.3
  • 13
    • 33745712926 scopus 로고    scopus 로고
    • Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo
    • First in vivo study on astrocytic Ca2+ signaling evoked by sensory stimulation.
    • Wang X, Lou N, Xu Q et al. Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo. Nat. Neurosci. 9(6), 816-823 (2006). First in vivo study on astrocytic Ca2+ signaling evoked by sensory stimulation.
    • (2006) Nat. Neurosci. , vol.9 , Issue.6 , pp. 816-823
    • Wang, X.1    Lou, N.2    Xu, Q.3
  • 14
    • 84877269867 scopus 로고    scopus 로고
    • In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase
    • Nizar K, Uhlirova H, Tian P et al. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J. Neurosci. 33(19), 8411-8422 (2013).
    • (2013) J. Neurosci. , vol.33 , Issue.19 , pp. 8411-8422
    • Nizar, K.1    Uhlirova, H.2    Tian, P.3
  • 15
    • 51349138882 scopus 로고    scopus 로고
    • Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes
    • Meier SD, Kafitz KW, Rose CR, Meier SD, Kafitz KW, Rose CR. Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes. Glia 56(10), 1127-1137 (2008).
    • (2008) Glia , vol.56 , Issue.10 , pp. 1127-1137
    • Meier, S.D.1    Kafitz, K.W.2    Rose, C.R.3    Meier, S.D.4    Kafitz, K.W.5    Rose, C.R.6
  • 16
    • 52049121361 scopus 로고    scopus 로고
    • Locus coeruleus a-adrenergic-comediated activation of cortical astrocytes in vivo
    • Bekar LK, He W, Nedergaard M. Locus coeruleus a-adrenergic-comediated activation of cortical astrocytes in vivo. Cerebral Cortex 18(12), 2789-2795 (2008).
    • (2008) Cerebral Cortex , vol.18 , Issue.12 , pp. 2789-2795
    • Bekar, L.K.1    He, W.2    Nedergaard, M.3
  • 17
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon PG , Carmignoto G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol. Rev. 86(3), 1009-1031 (2006).
    • (2006) Physiol. Rev. , vol.86 , Issue.3 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 18
    • 35448981357 scopus 로고    scopus 로고
    • Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons
    • Ni Y, Malarkey EB, Parpura V. Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons. J. Neurochem. 103(4), 1273-1284 (2007).
    • (2007) J. Neurochem. , vol.103 , Issue.4 , pp. 1273-1284
    • Ni, Y.1    Malarkey, E.B.2    Parpura, V.3
  • 19
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP , Duvoisin R. The metabotropic glutamate receptors: Structure and functions. Neuropharmacology 34(1), 1-26 (1995).
    • (1995) Neuropharmacology , vol.34 , Issue.1 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 20
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • Schoepp DD, Jane DE, Monn JA. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38(10), 1431-1476 (1999).
    • (1999) Neuropharmacology , vol.38 , Issue.10 , pp. 1431-1476
    • Schoepp, D.D.1    De, J.2    Monn, J.A.3
  • 21
    • 77949516412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Physiology, pharmacology, and disease
    • Niswender CM , Conn PJ. Metabotropic glutamate receptors: Physiology, pharmacology, and disease. Annu. Rev. Pharmacol. Toxicol. 50(1), 295-322 (2010).
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , Issue.1 , pp. 295-322
    • Niswender, C.M.1    Conn, P.J.2
  • 22
    • 0033571654 scopus 로고    scopus 로고
    • MGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats
    • Schools GP , Kimelberg HK. mGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats. J. Neurosci. Res. 58(4), 533-543 (1999).
    • (1999) J. Neurosci. Res. , vol.58 , Issue.4 , pp. 533-543
    • Schools, G.P.1    Kimelberg, H.K.2
  • 24
    • 31744448589 scopus 로고    scopus 로고
    • Functional expression of metabotropic GABAB receptors in primary cultures of astrocytes from rat cerebral cortex
    • Oka M, Wada M, Wu Q, Yamamoto A, Fujita T. Functional expression of metabotropic GABAB receptors in primary cultures of astrocytes from rat cerebral cortex. Biochem. Biophys. Res. Commun. 341(3), 874-881 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.341 , Issue.3 , pp. 874-881
    • Oka, M.1    Wada, M.2    Wu, Q.3    Yamamoto, A.4    Fujita, T.5
  • 25
    • 0141838195 scopus 로고    scopus 로고
    • GABA B receptor subunit expression in glia
    • Charles KJ, Deuchars J, Davies CH et al. GABA B receptor subunit expression in glia. Mol. Cell. Neurosci. 24(1), 214-223 (2003).
    • (2003) Mol. Cell. Neurosci. , vol.24 , Issue.1 , pp. 214-223
    • Charles, K.J.1    Deuchars, J.2    Ch, D.3
  • 26
    • 0032247897 scopus 로고    scopus 로고
    • Astrocyte-mediated potentiation of inhibitory synaptic transmission
    • Kang J, Jiang L, Goldman SA, Nedergaard M. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat. Neurosci. 1(8), 683-692 (1998).
    • (1998) Nat. Neurosci. , vol.1 , Issue.8 , pp. 683-692
    • Kang, J.1    Jiang, L.2    Goldman, S.A.3    Nedergaard, M.4
  • 28
    • 44949238601 scopus 로고    scopus 로고
    • Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline ca1 pyramidal neuron synaptic activity
    • Petravicz J, Fiacco TA, McCarthy KD. Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline ca1 pyramidal neuron synaptic activity. J. Neurosci. 28(19), 4967-4973 (2008).
    • (2008) J. Neurosci. , vol.28 , Issue.19 , pp. 4967-4973
    • Petravicz, J.1    Fiacco, T.A.2    McCarthy, K.D.3
  • 29
    • 36649003742 scopus 로고    scopus 로고
    • Distribution of inositol-1,4,5- trisphosphate receptor isotypes and ryanodine receptor isotypes during maturation of the rat hippocampus
    • Hertle DN, Yeckel MF, Hertle DN, Yeckel MF. Distribution of inositol-1,4,5- trisphosphate receptor isotypes and ryanodine receptor isotypes during maturation of the rat hippocampus. Neuroscience 150(3), 625-638 (2007).
    • (2007) Neuroscience , vol.150 , Issue.3 , pp. 625-638
    • Hertle, D.N.1    Yeckel, M.F.2    Hertle, D.N.3    Yeckel, M.F.4
  • 30
    • 0036628510 scopus 로고    scopus 로고
    • Astrocytes in adult rat brain express type 2 inositol 1,4,5-trisphosphate receptors
    • Holtzclaw LA, Pandhit S, Bare DJ et al. Astrocytes in adult rat brain express type 2 inositol 1,4,5-trisphosphate receptors. Glia 39(1), 69-84 (2002).
    • (2002) Glia , vol.39 , Issue.1 , pp. 69-84
    • Holtzclaw, L.A.1    Pandhit, S.2    Bare, D.J.3
  • 31
    • 0033526114 scopus 로고    scopus 로고
    • Differential cellular expression of isoforms of inositol 1 4,5-triphosphate receptors in neurons and glia in brain
    • Sharp AH, Nucifora FC Jr, Blondel O et al. Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain. J. Comp. Neurol. 406(2), 207-220 (1999).
    • (1999) J. Comp. Neurol. , vol.406 , Issue.2 , pp. 207-220
    • Sharp, A.H.1    Nucifora Jr., F.C.2    Blondel, O.3
  • 32
    • 84857661461 scopus 로고    scopus 로고
    • Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes
    • Reyes RC, Verkhratsky A, Parpura V. Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes. ASN Neuro. 4(1), e00075 (2012).
    • (2012) ASN Neuro. , vol.4 , Issue.1
    • Reyes, R.C.1    Verkhratsky, A.2    Parpura, V.3
  • 34
    • 84861527728 scopus 로고    scopus 로고
    • P2X receptors and their roles in astroglia in the central and peripheral nervous system
    • Illes P, Verkhratsky A, Burnstock G, Franke H. P2X receptors and their roles in astroglia in the central and peripheral nervous system. Neuroscientist 18(5), 422-438 (2012).
    • (2012) Neuroscientist , vol.18 , Issue.5 , pp. 422-438
    • Illes, P.1    Verkhratsky, A.2    Burnstock, G.3    Franke, H.4
  • 35
    • 84555172978 scopus 로고    scopus 로고
    • TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3
    • Shigetomi E, Tong X, Kwan KY, Corey DP, Khakh BS. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat. Neurosci. 15(1), 70-80 (2012).
    • (2012) Nat. Neurosci. , vol.15 , Issue.1 , pp. 70-80
    • Shigetomi, E.1    Tong, X.2    Kwan, K.Y.3    Corey, D.P.4    Khakh, B.S.5
  • 36
    • 77957371582 scopus 로고    scopus 로고
    • Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes
    • Shirakawa H, Sakimoto S, Nakao K et al. Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes. J. Neurosci. 30(39), 13116-13129 (2010).
    • (2010) J. Neurosci. , vol.30 , Issue.39 , pp. 13116-13129
    • Shirakawa, H.1    Sakimoto, S.2    Nakao, K.3
  • 38
    • 33846933444 scopus 로고    scopus 로고
    • MGluR5 stimulates gliotransmission in the nucleus accumbens
    • DAscenzo M, Fellin T, Terunuma M et al. mGluR5 stimulates gliotransmission in the nucleus accumbens. Proc. Natl Acad. Sci. USA 104(6), 1995-2000 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.6 , pp. 1995-2000
    • Dascenzo, M.1    Fellin, T.2    Terunuma, M.3
  • 39
    • 3843109172 scopus 로고    scopus 로고
    • Glutamate released from glial cells synchronizes neuronal activity in the hippocampus
    • Angulo MC, Kozlov AS, Charpak S, Audinat E. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. J. Neurosci. 24(31), 6920-6927 (2004).
    • (2004) J. Neurosci. , vol.24 , Issue.31 , pp. 6920-6927
    • Angulo, M.C.1    Kozlov, A.S.2    Charpak, S.3    Audinat, E.4
  • 40
    • 0030820823 scopus 로고    scopus 로고
    • Intracellular calcium oscillations in astrocytes: A highly plastic, bidirectional form of communication between neurons and astrocytes in situ
    • Pasti L, Volterra A, Pozzan T, Carmignoto G. Intracellular calcium oscillations in astrocytes: A highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J. Neurosci. 17(20), 7817-7830 (1997).
    • (1997) J. Neurosci. , vol.17 , Issue.20 , pp. 7817-7830
    • Pasti, L.1    Volterra, A.2    Pozzan, T.3    Carmignoto, G.4
  • 41
    • 0029758991 scopus 로고    scopus 로고
    • Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals
    • Porter JT, McCarthy KD. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J. Neurosci. 16(16), 5073-5081 (1996).
    • (1996) J. Neurosci. , vol.16 , Issue.16 , pp. 5073-5081
    • Porter, J.T.1    McCarthy, K.D.2
  • 42
    • 33847183442 scopus 로고    scopus 로고
    • Glutamate exocytosis from astrocytes controls synaptic strength
    • Jourdain P, Bergersen LH, Bhaukaurally K et al. Glutamate exocytosis from astrocytes controls synaptic strength. Nat. Neurosci. 10(3), 331-339 (2007).
    • (2007) Nat. Neurosci. , vol.10 , Issue.3 , pp. 331-339
    • Jourdain, P.1    Bergersen, L.H.2    Bhaukaurally, K.3
  • 43
    • 0034743201 scopus 로고    scopus 로고
    • Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation
    • Parri HR, Gould TM, Crunelli V. Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation. Nat. Neurosci. 4(8), 803-812 (2001).
    • (2001) Nat. Neurosci. , vol.4 , Issue.8 , pp. 803-812
    • Parri, H.R.1    Gould, T.M.2    Crunelli, V.3
  • 45
    • 26444552361 scopus 로고    scopus 로고
    • Astrocytic purinergic signaling coordinates synaptic networks
    • Pascual O, Casper KB, Kubera C et al. Astrocytic purinergic signaling coordinates synaptic networks. Science 310(5745), 113-116 (2005).
    • (2005) Science , vol.310 , Issue.5745 , pp. 113-116
    • Pascual, O.1    Casper, K.B.2    Kubera, C.3
  • 46
    • 0035313160 scopus 로고    scopus 로고
    • Propagation of intercellular calcium waves in retinal astrocytes and Muller cells
    • Newman EA. Propagation of intercellular calcium waves in retinal astrocytes and Muller cells. J. Neurosci. 21(7), 2215-2223 (2001).
    • (2001) J. Neurosci. , vol.21 , Issue.7 , pp. 2215-2223
    • Newman, E.A.1
  • 47
    • 17244382523 scopus 로고    scopus 로고
    • Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter d-serine
    • Mothet JP, Pollegioni L, Ouanounou G, Martineau M, Fossier P, Baux G. Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter d-serine. Proc. Natl Acad. Sci. USA 102(15), 5606-5611 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.15 , pp. 5606-5611
    • Mothet, J.P.1    Pollegioni, L.2    Ouanounou, G.3    Martineau, M.4    Fossier, P.5    Baux, G.6
  • 48
    • 74549135360 scopus 로고    scopus 로고
    • Long-term potentiation depends on release of d-serine from astrocytes
    • Henneberger C, Papouin T, Oliet SH, Rusakov DA. Long-term potentiation depends on release of d-serine from astrocytes. Nature 463(7278), 232-236 (2010).
    • (2010) Nature , vol.463 , Issue.7278 , pp. 232-236
    • Henneberger, C.1    Papouin, T.2    Oliet, S.H.3    Rusakov, D.A.4
  • 49
    • 84874196604 scopus 로고    scopus 로고
    • Storage and Uptake of d-serine into astrocytic synaptic-like vesicles specify gliotransmission
    • Martineau M, Shi T, Puyal J et al. Storage and Uptake of d-serine into astrocytic synaptic-like vesicles specify gliotransmission. J. Neurosci. 33(8), 3413-3423 (2013).
    • (2013) J. Neurosci. , vol.33 , Issue.8 , pp. 3413-3423
    • Martineau, M.1    Shi, T.2    Puyal, J.3
  • 50
    • 84874255913 scopus 로고    scopus 로고
    • Astrocyte-induced cortical vasodilation is mediated by d-serine and endothelial nitric oxide synthase
    • Stobart JLL, Lu L, Anderson HDI, Mori H, Anderson CM. Astrocyte-induced cortical vasodilation is mediated by d-serine and endothelial nitric oxide synthase. Proc. Natl Acad. Sci. USA (2013).
    • (2013) Proc. Natl Acad. Sci. USA
    • Jll, S.1    Lu, L.2    Hdi, A.3    Mori, H.4    Anderson, C.M.5
  • 51
    • 83055160837 scopus 로고    scopus 로고
    • Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo
    • In vivo study on the role of astrocytic Ca2+ in neuronal plasticity.
    • Takata N, Mishima T, Hisatsune C et al. Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo. J. Neurosci. 31(49), 18155-18165 (2011). In vivo study on the role of astrocytic Ca2+ in neuronal plasticity.
    • (2011) J. Neurosci. , vol.31 , Issue.49 , pp. 18155-18165
    • Takata, N.1    Mishima, T.2    Hisatsune, C.3
  • 52
    • 84867363374 scopus 로고    scopus 로고
    • Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes
    • Chen N, Sugihara H, Sharma J et al. Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes. Proc. Natl Acad. Sci. USA 109(41), E2832- E2841 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.41
    • Chen, N.1    Sugihara, H.2    Sharma, J.3
  • 53
    • 84857494906 scopus 로고    scopus 로고
    • Astrocytes mediate in vivo cholinergic-induced synaptic plasticity
    • Navarrete M, Perea G, de Sevilla DF et al. Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol. 10(2), e1001259 (2012).
    • (2012) PLoS Biol. , vol.10 , Issue.2
    • Navarrete, M.1    Perea, G.2    De Sevilla, D.F.3
  • 54
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk W, Strickler JH, Webb WW. Two-photon laser scanning fluorescence microscopy. Science 248(4951), 73-76 (1990).
    • (1990) Science , vol.248 , Issue.4951 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 55
    • 19344362473 scopus 로고    scopus 로고
    • Calcium dynamics of cortical astrocytic networks in vivo
    • First paper to study astrocytic Ca2+ signaling in vivo using two-photon microscopy.
    • Hirase H, Qian L, Bartho P et al. Calcium dynamics of cortical astrocytic networks in vivo. PLoS Biol. 2(4), E96 (2004). First paper to study astrocytic Ca2+ signaling in vivo using two-photon microscopy.
    • (2004) PLoS Biol. , vol.2 , Issue.4
    • Hirase, H.1    Qian, L.2    Bartho, P.3
  • 56
    • 0242353872 scopus 로고    scopus 로고
    • Nonlinear magic: Multiphoton microscopy in the biosciences
    • Zipfel WR, Williams RM, Webb WW. Nonlinear magic: multiphoton microscopy in the biosciences. Nat. Biotech. 21(11), 1369-1377 (2003).
    • (2003) Nat. Biotech. , vol.21 , Issue.11 , pp. 1369-1377
    • Zipfel, W.R.1    Williams, R.M.2    Webb, W.W.3
  • 57
    • 18744409106 scopus 로고    scopus 로고
    • Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
    • First paper to report selective labeling of astrocytes in vivo.
    • Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat. Meth. 1(1), 31-37 (2004). First paper to report selective labeling of astrocytes in vivo.
    • (2004) Nat. Meth. , vol.1 , Issue.1 , pp. 31-37
    • Nimmerjahn, A.1    Kirchhoff, F.2    Kerr, J.N.3    Helmchen, F.4
  • 59
    • 78650248298 scopus 로고    scopus 로고
    • Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice
    • Yang Y, Vidensky S, Jin L et al. Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice. Glia 59(2), 200-207 (2011).
    • (2011) Glia , vol.59 , Issue.2 , pp. 200-207
    • Yang, Y.1    Vidensky, S.2    Jin, L.3
  • 60
    • 0041342075 scopus 로고    scopus 로고
    • GFAP promoter drives muller cell specific expression in transgenic mice
    • Kuzmanovic M, Dudley VJ, Sarthy VP. GFAP promoter drives muller cell specific expression in transgenic mice. Invest. Ophthalmol. Vis. Sci. 44(8), 3606-3613 (2003).
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , Issue.8 , pp. 3606-3613
    • Kuzmanovic, M.1    Dudley, V.J.2    Sarthy, V.P.3
  • 61
    • 0035132767 scopus 로고    scopus 로고
    • GFAP promoter-controlled EGFP-expressing transgenic mice. A tool to visualize astrocytes and astrogliosis in living brain tissue
    • Nolte C, Matyash M, Pivneva T et al. GFAP promoter-controlled EGFP-expressing transgenic mice. A tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33(1), 72-86 (2001).
    • (2001) Glia , vol.33 , Issue.1 , pp. 72-86
    • Nolte, C.1    Matyash, M.2    Pivneva, T.3
  • 62
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat. Meth. 2(12), 932-940 (2005).
    • (2005) Nat. Meth. , vol.2 , Issue.12 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 64
    • 33750681649 scopus 로고    scopus 로고
    • Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain
    • Tian GF, Takano T, Lin JH et al. Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain. Adv. Drug Deliv. Rev. 58(7), 773-787 (2006).
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , Issue.7 , pp. 773-787
    • Tian, G.F.1    Takano, T.2    Lin, J.H.3
  • 65
    • 73349108496 scopus 로고    scopus 로고
    • Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
    • Tian L, Hires SA, Mao T et al. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat. Meth. 6(12), 875-881 (2009).
    • (2009) Nat. Meth. , vol.6 , Issue.12 , pp. 875-881
    • Tian, L.1    Hires, S.A.2    Mao, T.3
  • 66
    • 84863229120 scopus 로고    scopus 로고
    • A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo
    • Zariwala HA, Borghuis BG, Hoogland TM et al. A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo. J. Neurosci. 32(9), 3131-3141 (2012).
    • (2012) J. Neurosci. , vol.32 , Issue.9 , pp. 3131-3141
    • Zariwala, H.A.1    Borghuis, B.G.2    Hoogland, T.M.3
  • 67
    • 84867026349 scopus 로고    scopus 로고
    • Optimization of a GCaMP calcium indicator for neural activity imaging
    • Akerboom J, Chen TW, Wardill TJ et al. Optimization of a GCaMP calcium indicator for neural activity imaging. J. Neurosci. 32(40), 13819-13840 (2012).
    • (2012) J. Neurosci. , vol.32 , Issue.40 , pp. 13819-13840
    • Akerboom, J.1    Chen, T.W.2    Wardill, T.J.3
  • 68
    • 84878590590 scopus 로고    scopus 로고
    • Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses
    • Shigetomi E, Bushong EA, Haustein MD et al. Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. J. Gen. Physiol. 141(5), 633-647 (2013).
    • (2013) J. Gen. Physiol. , vol.141 , Issue.5 , pp. 633-647
    • Shigetomi, E.1    Bushong, E.A.2    Haustein, M.D.3
  • 69
    • 77957107083 scopus 로고    scopus 로고
    • Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction
    • Study using adeno-associated virus to selectively express transgenes and inhibit astrocytic Ca2+ signaling pathway.
    • Xie Y, Wang T, Sun GY, Ding S. Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction. Neuroscience 170(4), 992-1003 (2010). Study using adeno-associated virus to selectively express transgenes and inhibit astrocytic Ca2+ signaling pathway.
    • (2010) Neuroscience , vol.170 , Issue.4 , pp. 992-1003
    • Xie, Y.1    Wang, T.2    Sun, G.Y.3    Ding, S.4
  • 70
    • 84877742824 scopus 로고    scopus 로고
    • Genetically encoded calcium indicators and astrocyte calcium microdomains
    • Tong X, Shigetomi E, Looger LL, Khakh BS. Genetically encoded calcium indicators and astrocyte calcium microdomains. Neuroscientist 19(3), 274-291 (2013).
    • (2013) Neuroscientist , vol.19 , Issue.3 , pp. 274-291
    • Tong, X.1    Shigetomi, E.2    Looger, L.L.3    Khakh, B.S.4
  • 71
    • 49649116157 scopus 로고    scopus 로고
    • Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo
    • Takata N, Hirase H. Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo. PLoS ONE 3(6), e2525 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.6
    • Takata, N.1    Hirase, H.2
  • 72
    • 79951833491 scopus 로고    scopus 로고
    • Large-scale calcium waves traveling through astrocytic networks in vivo
    • Kuga N, Sasaki T, Takahara Y, Matsuki N, Ikegaya Y. Large-scale calcium waves traveling through astrocytic networks in vivo. J. Neurosci. 31(7), 2607-2614 (2011).
    • (2011) J. Neurosci. , vol.31 , Issue.7 , pp. 2607-2614
    • Kuga, N.1    Sasaki, T.2    Takahara, Y.3    Matsuki, N.4    Ikegaya, Y.5
  • 74
    • 30744450905 scopus 로고    scopus 로고
    • Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves
    • Haas B, Schipke CG, Peters O, Söhl G, Willecke K, Kettenmann H. Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves. Cerebral Cortex 16(2), 237-246 (2006).
    • (2006) Cerebral Cortex , vol.16 , Issue.2 , pp. 237-246
    • Haas, B.1    Schipke, C.G.2    Peters, O.3    Söhl, G.4    Willecke, K.5    Kettenmann, H.6
  • 75
    • 65549146280 scopus 로고    scopus 로고
    • Motor behavior activates Bergmann glial networks
    • Study on Bergmann glial Ca2+ responses to motor behavior in awake and behaving animals.
    • Nimmerjahn A, Mukamel EA, Schnitzer MJ. Motor behavior activates Bergmann glial networks. Neuron 62(3), 400-412 (2009). Study on Bergmann glial Ca2+ responses to motor behavior in awake and behaving animals.
    • (2009) Neuron , vol.62 , Issue.3 , pp. 400-412
    • Nimmerjahn, A.1    Mukamel, E.A.2    Schnitzer, M.J.3
  • 76
    • 34748867201 scopus 로고    scopus 로고
    • Imaging large-scale neural activity with cellular resolution in awake, mobile mice
    • Dombeck DA, Khabbaz AN, Collman F, Adelman TL, Tank DW. Imaging large-scale neural activity with cellular resolution in awake, mobile mice. Neuron 56(1), 43-57 (2007).
    • (2007) Neuron , vol.56 , Issue.1 , pp. 43-57
    • Dombeck, D.A.1    Khabbaz, A.N.2    Collman, F.3    Adelman, T.L.4    Tank, D.W.5
  • 77
    • 31544456102 scopus 로고    scopus 로고
    • Astrocyte-mediated control of cerebral blood flow
    • First in vivo study on astrocytic Ca2+ signaling on neurovascular coupling.
    • Takano T, Tian GF, Peng W et al. Astrocyte-mediated control of cerebral blood flow. Nat. Neurosci. 9(2), 260-267 (2006). First in vivo study on astrocytic Ca2+ signaling on neurovascular coupling.
    • (2006) Nat. Neurosci. , vol.9 , Issue.2 , pp. 260-267
    • Takano, T.1    Tian, G.F.2    Peng, W.3
  • 78
    • 24744449939 scopus 로고    scopus 로고
    • An astrocytic basis of epilepsy
    • Tian GF, Azmi H, Takano T et al. An astrocytic basis of epilepsy. Nat. Med. 11, 973-981, (2005).
    • (2005) Nat. Med. , vol.11 , pp. 973-981
    • Tian, G.F.1    Azmi, H.2    Takano, T.3
  • 79
    • 34249980900 scopus 로고    scopus 로고
    • Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo
    • Winship IR, Plaa N, Murphy TH. Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo. J. Neurosci. 27(23), 6268-6272 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.23 , pp. 6268-6272
    • Winship, I.R.1    Plaa, N.2    Murphy, T.H.3
  • 80
    • 84873736923 scopus 로고    scopus 로고
    • Somatotopic astrocytic activity in the somatosensory cortex
    • Ghosh A, Wyss MT, Weber B. Somatotopic astrocytic activity in the somatosensory cortex. Glia 61(4), 601-610 (2013).
    • (2013) Glia , vol.61 , Issue.4 , pp. 601-610
    • Ghosh, A.1    Wyss, M.T.2    Weber, B.3
  • 81
    • 46249088975 scopus 로고    scopus 로고
    • Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex
    • Study on astrocytic response to visual stimulation in vivo.
    • Schummers J, Yu H, Sur M. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex. Science 320(5883), 1638-1643 (2008). Study on astrocytic response to visual stimulation in vivo.
    • (2008) Science , vol.320 , Issue.5883 , pp. 1638-1643
    • Schummers, J.1    Yu, H.2    Sur, M.3
  • 82
    • 45249086342 scopus 로고    scopus 로고
    • Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways
    • Study on astrocytic responses to odor stimulation in vivo.
    • Petzold GC, Albeanu DF, Sato TF et al. Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron 58(6), 897-910 (2008). Study on astrocytic responses to odor stimulation in vivo.
    • (2008) Neuron , vol.58 , Issue.6 , pp. 897-910
    • Petzold, G.C.1    Albeanu, D.F.2    Sato, T.F.3
  • 83
    • 34248545253 scopus 로고    scopus 로고
    • Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity
    • Fiacco TA, Agulhon C, Taves SR et al. Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron 54(4), 611-626 (2007).
    • (2007) Neuron , vol.54 , Issue.4 , pp. 611-626
    • Fiacco, T.A.1    Agulhon, C.2    Taves, S.R.3
  • 84
    • 77749292042 scopus 로고    scopus 로고
    • Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling
    • Important study showing astrocytic Ca2+ has no effect on synaptic plasticity.
    • Agulhon C, Fiacco TA, McCarthy KD. Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling. Science 327(5970), 1250-1254 (2010). Important study showing astrocytic Ca2+ has no effect on synaptic plasticity.
    • (2010) Science , vol.327 , Issue.5970 , pp. 1250-1254
    • Agulhon, C.1    Fiacco, T.A.2    McCarthy, K.D.3
  • 85
    • 0037223147 scopus 로고    scopus 로고
    • Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
    • Zonta M, Angulo MC, Gobbo S et al. Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat. Neurosci. 6(1), 43-50 (2003).
    • (2003) Nat. Neurosci. , vol.6 , Issue.1 , pp. 43-50
    • Zonta, M.1    Angulo, M.C.2    Gobbo, S.3
  • 86
    • 57649118670 scopus 로고    scopus 로고
    • Brain metabolism dictates the polarity of astrocyte control over arterioles
    • Gordon GR, Choi HB, Rungta RL, Ellis-Davies GC, MacVicar BA. Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456(7223), 745-749 (2008).
    • (2008) Nature , vol.456 , Issue.7223 , pp. 745-749
    • Gordon, G.R.1    Choi, H.B.2    Rungta, R.L.3    Ellis-Davies, G.C.4    Macvicar, B.A.5
  • 87
    • 80055085367 scopus 로고    scopus 로고
    • Oxygen modulation of neurovascular coupling in the retina
    • Mishra A, Hamid A, Newman EA. Oxygen modulation of neurovascular coupling in the retina. Proc. Natl Acad. Sci. USA 108(43), 17827-17831 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.43 , pp. 17827-17831
    • Mishra, A.1    Hamid, A.2    Newman, E.A.3
  • 89
    • 80052415710 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response
    • Calcinaghi N, Jolivet R, Wyss MT et al. Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response. J. Cereb. Blood Flow Metab. 31(9), e1-e10 (2011).
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , Issue.9
    • Calcinaghi, N.1    Jolivet, R.2    Wyss, M.T.3
  • 90
    • 34247148660 scopus 로고    scopus 로고
    • High-resolution in vivo imaging of the neurovascular unit during spreading depression
    • Chuquet J, Hollender L, Nimchinsky EA. High-resolution in vivo imaging of the neurovascular unit during spreading depression. J. Neurosci. 27(15), 4036-4044 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.15 , pp. 4036-4044
    • Chuquet, J.1    Hollender, L.2    Nimchinsky, E.A.3
  • 91
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634 (1988).
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.1
  • 92
    • 59649092943 scopus 로고    scopus 로고
    • Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia
    • Medvedeva YV, Lin B, Shuttleworth CW, Weiss JH. Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia. J. Neurosci. 29(4), 1105-1114 (2009).
    • (2009) J. Neurosci. , vol.29 , Issue.4 , pp. 1105-1114
    • Medvedeva, Y.V.1    Lin, B.2    Shuttleworth, C.W.3    Weiss, J.H.4
  • 93
    • 0030814002 scopus 로고    scopus 로고
    • Mechanisms underlying the rapid depolarization produced by deprivation of oxygen and glucose in rat hippocampal CA1 neurons in vitro
    • Tanaka E, Yamamoto S, Kudo Y, Mihara S, Higashi H. Mechanisms underlying the rapid depolarization produced by deprivation of oxygen and glucose in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 78(2), 891-902 (1997).
    • (1997) J. Neurophysiol. , vol.78 , Issue.2 , pp. 891-902
    • Tanaka, E.1    Yamamoto, S.2    Kudo, Y.3    Mihara, S.4    Higashi, H.5
  • 95
    • 3042793425 scopus 로고    scopus 로고
    • Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis
    • Kasischke KA, Vishwasrao HD, Fisher PJ, Zipfel WR, Webb WW. Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis. Science 305(5680), 99-103 (2004).
    • (2004) Science , vol.305 , Issue.5680 , pp. 99-103
    • Kasischke, K.A.1    Vishwasrao, H.D.2    Fisher, P.J.3    Zipfel, W.R.4    Webb, W.W.5
  • 96
    • 2042420664 scopus 로고    scopus 로고
    • Brain glycogen re-awakened
    • Brown AM. Brain glycogen re-awakened. J. Neurochem. 89(3), 537-552 (2004).
    • (2004) J. Neurochem. , vol.89 , Issue.3 , pp. 537-552
    • Brown, A.M.1
  • 97
    • 35548957889 scopus 로고    scopus 로고
    • Astrocyte metabolism and signaling during brain ischemia
    • Rossi DJ, Brady JD, Mohr C. Astrocyte metabolism and signaling during brain ischemia. Nat. Neurosci. 10(11), 1377-1386 (2007).
    • (2007) Nat. Neurosci. , vol.10 , Issue.11 , pp. 1377-1386
    • Rossi, D.J.1    Brady, J.D.2    Mohr, C.3
  • 98
    • 69949147227 scopus 로고    scopus 로고
    • Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis
    • Gurer G, Gursoy-Ozdemir Y, Erdemli E, Can A, Dalkara T. Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis. Brain Pathol. 19, 630-641 (2009).
    • (2009) Brain Pathol. , vol.19 , pp. 630-641
    • Gurer, G.1    Gursoy-Ozdemir, Y.2    Erdemli, E.3    Can, A.4    Dalkara, T.5
  • 99
    • 20344394153 scopus 로고    scopus 로고
    • Role of glial cells in cerebral ischemia
    • Nedergaard M, Dirnagl U. Role of glial cells in cerebral ischemia. Glia 50(4), 281-286 (2005).
    • (2005) Glia , vol.50 , Issue.4 , pp. 281-286
    • Nedergaard, M.1    Dirnagl, U.2
  • 100
  • 101
    • 1842587600 scopus 로고    scopus 로고
    • Astrocyte influences on ischemic neuronal death
    • Swanson RA, Ying W, Kauppinen TM. Astrocyte influences on ischemic neuronal death. Curr. Mol. Med. 4(2), 193-205 (2004).
    • (2004) Curr. Mol. Med. , vol.4 , Issue.2 , pp. 193-205
    • Swanson, R.A.1    Ying, W.2    Kauppinen, T.M.3
  • 102
    • 20344374445 scopus 로고    scopus 로고
    • Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy
    • Kimelberg HK. Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia 50(4), 389-397 (2005).
    • (2005) Glia , vol.50 , Issue.4 , pp. 389-397
    • Kimelberg, H.K.1
  • 103
    • 20344366326 scopus 로고    scopus 로고
    • Astrocytes in cerebral ischemic injury: Morphological and general considerations
    • Panickar KS , Norenberg MD. Astrocytes in cerebral ischemic injury: morphological and general considerations. Glia 50(4), 287-298 (2005).
    • (2005) Glia , vol.50 , Issue.4 , pp. 287-298
    • Panickar, K.S.1    Norenberg, M.D.2
  • 104
    • 20344398223 scopus 로고    scopus 로고
    • Astrocyte activation and reactive gliosis
    • Pekny M, Nilsson M. Astrocyte activation and reactive gliosis. Glia 50(4), 427-434 (2005).
    • (2005) Glia , vol.50 , Issue.4 , pp. 427-434
    • Pekny, M.1    Nilsson, M.2
  • 105
    • 77549083577 scopus 로고    scopus 로고
    • Calcium, ischemia and excitotoxicity
    • Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium 47(2), 122-129 (2010).
    • (2010) Cell Calcium , vol.47 , Issue.2 , pp. 122-129
    • Szydlowska, K.1    Tymianski, M.2
  • 106
    • 78649717751 scopus 로고    scopus 로고
    • Controlling the volume of the focal cerebral ischemic lesion through photothrombosis
    • Wang T, Cui W, Xie YZ. Controlling the volume of the focal cerebral ischemic lesion through photothrombosis. Am. J. Biomed. Sci. 2, 33-42 (2010).
    • (2010) Am. J. Biomed. Sci. , vol.2 , Issue.33-42
    • Wang, T.1    Cui, W.2    Xie, Y.Z.3
  • 107
    • 78649696643 scopus 로고    scopus 로고
    • Neuronal protective role of PBEF in a mouse model of cerebral ischemia
    • Zhang W, Xie Y, Wang T et al. Neuronal protective role of PBEF in a mouse model of cerebral ischemia. J. Cereb. Blood Flow Metab. 30(12), 1962-1971 (2010).
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , Issue.12 , pp. 1962-1971
    • Zhang, W.1    Xie, Y.2    Wang, T.3
  • 108
    • 84880380152 scopus 로고    scopus 로고
    • Inhibition of the group i mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischemia
    • doi:10.1042/AN20130002 Epub ahead of print
    • Li H, Zhang N, Sun G, Ding S. Inhibition of the group I mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischemia. ASN Neuro. doi:10.1042/AN20130002 (2013) (Epub ahead of print).
    • (2013) ASN Neuro.
    • Li, H.1    Zhang, N.2    Sun, G.3    Ding, S.4
  • 109
    • 84865860670 scopus 로고    scopus 로고
    • Persistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations
    • Risher WC, Croom D, Kirov SA. Persistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations. Glia 60(11), 1709-1720 (2012).
    • (2012) Glia , vol.60 , Issue.11 , pp. 1709-1720
    • Risher, W.C.1    Croom, D.2    Kirov, S.A.3
  • 110
    • 77954838959 scopus 로고    scopus 로고
    • Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra
    • Risher WC, Ard D, Yuan J, Kirov SA. Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra. J. Neurosci. 30(29), 9859-9868 (2010).
    • (2010) J. Neurosci. , vol.30 , Issue.29 , pp. 9859-9868
    • Risher, W.C.1    Ard, D.2    Yuan, J.3    Kirov, S.A.4
  • 111
    • 48549087008 scopus 로고    scopus 로고
    • In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke
    • Winship IR, Murphy TH. In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke. J. Neurosci. 28(26), 6592-6606 (2008).
    • (2008) J. Neurosci. , vol.28 , Issue.26 , pp. 6592-6606
    • Winship, I.R.1    Murphy, T.H.2
  • 112
    • 20044374010 scopus 로고    scopus 로고
    • Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia
    • Zhang S, Boyd J, Delaney K, Murphy TH. Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J. Neurosci. 25(22), 5333-5338 (2005).
    • (2005) J. Neurosci. , vol.25 , Issue.22 , pp. 5333-5338
    • Zhang, S.1    Boyd, J.2    Delaney, K.3    Murphy, T.H.4
  • 113
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu. Rev. Neurosci. 24, 31-55 (2001).
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 114
    • 84874884587 scopus 로고    scopus 로고
    • Critical role of the astrocyte for functional remodeling in contralateral hemisphere of somatosensory cortex after stroke
    • Studied the changes of in vivo astrocytic Ca2+ signaling in ipsilateral and contralateral hemispheres in the chronic period of photothrombosis.
    • Takatsuru Y, Eto K, Kaneko R et al. Critical role of the astrocyte for functional remodeling in contralateral hemisphere of somatosensory cortex after stroke. J. Neurosci. 33(11), 4683-4692 (2013). Studied the changes of in vivo astrocytic Ca2+ signaling in ipsilateral and contralateral hemispheres in the chronic period of photothrombosis.
    • (2013) J. Neurosci. , vol.33 , Issue.11 , pp. 4683-4692
    • Takatsuru, Y.1    Eto, K.2    Kaneko, R.3
  • 116
    • 62549132717 scopus 로고    scopus 로고
    • Radially expanding transglial calcium waves in the intact cerebellum
    • Hoogland TM, Kuhn B, Göbel W et al. Radially expanding transglial calcium waves in the intact cerebellum. Proc. Natl Acad. Sci. USA 106(9), 3496-3501 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.9 , pp. 3496-3501
    • Hoogland, T.M.1    Kuhn, B.2    Göbel, W.3
  • 117
    • 84873407062 scopus 로고    scopus 로고
    • Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen
    • Ca2+ signaling of Bergmann glial cells in hypoxia.
    • Mathiesen C, Brazhe A, Thomsen K, Lauritzen M. Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen. J. Cereb. Blood Flow Metab. 33(2), 161-169 (2013). Ca2+ signaling of Bergmann glial cells in hypoxia.
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , Issue.2 , pp. 161-169
    • Mathiesen, C.1    Brazhe, A.2    Thomsen, K.3    Lauritzen, M.4
  • 118
    • 58149349792 scopus 로고    scopus 로고
    • Two-photon imaging during prolonged middle cerebral artery occlusion in mice reveals recovery of dendritic structure after reperfusion
    • Li P, Murphy TH. Two-photon imaging during prolonged middle cerebral artery occlusion in mice reveals recovery of dendritic structure after reperfusion. J. Neurosci. 28(46), 11970-11979 (2008).
    • (2008) J. Neurosci. , vol.28 , Issue.46 , pp. 11970-11979
    • Li, P.1    Murphy, T.H.2
  • 119
    • 84888203048 scopus 로고    scopus 로고
    • Glutamate and tumor-associated epilepsy: Glial cell dysfunction in the peritumoral environment
    • doi:10.1016/j.neuint.2013.01.027 Epub ahead of print
    • Buckingham SC, Robel S. Glutamate and tumor-associated epilepsy: Glial cell dysfunction in the peritumoral environment. Neurochem. Int. doi:10.1016/j. neuint.2013.01.027 (2013) (Epub ahead of print).
    • (2013) Neurochem. Int.
    • Buckingham, S.C.1    Robel, S.2
  • 120
    • 0024444281 scopus 로고
    • Mossy fiber synaptic reorganization in the epileptic human temporal lobe
    • Sutula T, Cascino G, Cavazos J, Parada I, Ramirez L. Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann. Neurol. 26(3), 321-330 (1989).
    • (1989) Ann. Neurol. , vol.26 , Issue.3 , pp. 321-330
    • Sutula, T.1    Cascino, G.2    Cavazos, J.3    Parada, I.4    Ramirez, L.5
  • 121
    • 0032617980 scopus 로고    scopus 로고
    • Neuronal loss and synaptic reorganization in temporal lobe epilepsy
    • Houser CR. Neuronal loss and synaptic reorganization in temporal lobe epilepsy. Adv. Neurol. 79, 743-761 (1999).
    • (1999) Adv. Neurol. , vol.79 , pp. 743-761
    • Houser, C.R.1
  • 122
    • 0030559684 scopus 로고    scopus 로고
    • Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures
    • Houser CR, Esclapez M. Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures. Epilepsy Res. 26(1), 207-218 (1996).
    • (1996) Epilepsy Res. , vol.26 , Issue.1 , pp. 207-218
    • Houser, C.R.1    Esclapez, M.2
  • 123
    • 0027034178 scopus 로고
    • Granule cell disorganization in the dentate gyrus: Possible alterations of neuronal migration in human temporal lobe epilepsy
    • Houser CR, Swartz BE, Walsh GO, Delgado-Escueta AV. Granule cell disorganization in the dentate gyrus: Possible alterations of neuronal migration in human temporal lobe epilepsy. Epilepsy Res. SUPPL. 9, 41-48 (1992).
    • (1992) Epilepsy Res. Suppl. , vol.9 , pp. 41-48
    • Houser, C.R.1    Swartz, B.E.2    Walsh, G.O.3    Delgado-Escueta, A.V.4
  • 124
    • 0027033707 scopus 로고
    • Morphological changes in the dentate gyrus in human temporal lobe epilepsy
    • Houser CR. Morphological changes in the dentate gyrus in human temporal lobe epilepsy. Epilepsy Res.SUPPL. 7, 223-234 (1992).
    • (1992) Epilepsy Res.Suppl. , vol.7 , pp. 223-234
    • Houser, C.R.1
  • 125
    • 0024412565 scopus 로고
    • Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
    • de Lanerolle NC, Kim JH, Robbins RJ, Spencer DD. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res. 495(2), 387-395 (1989).
    • (1989) Brain Res. , vol.495 , Issue.2 , pp. 387-395
    • De Lanerolle, N.C.1    Kim, J.H.2    Robbins, R.J.3    Spencer, D.D.4
  • 128
    • 0036498359 scopus 로고    scopus 로고
    • Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy
    • Fonseca CG, Green CR, Nicholson LF. Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy. Brain Res. 929(1), 105-116 (2002).
    • (2002) Brain Res. , vol.929 , Issue.1 , pp. 105-116
    • Fonseca, C.G.1    Green, C.R.2    Nicholson, L.F.3
  • 129
    • 0036337697 scopus 로고    scopus 로고
    • Characterization of reactive astrocytes in the chronic phase of the pilocarpine model of epilepsy
    • Garzillo CL, Mello LE. Characterization of reactive astrocytes in the chronic phase of the pilocarpine model of epilepsy. Epilepsia 43(SUPPL. 5), 107-109 (2002).
    • (2002) Epilepsia , vol.43 , Issue.SUPPL. 5 , pp. 107-109
    • Garzillo, C.L.1    Mello, L.E.2
  • 130
    • 0028838991 scopus 로고
    • Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats
    • Lemos T, Cavalheiro EA. Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats. Exp. Brain Res. 102(3), 423-428 (1995).
    • (1995) Exp. Brain Res. , vol.102 , Issue.3 , pp. 423-428
    • Lemos, T.1    Cavalheiro, E.A.2
  • 131
    • 7944220701 scopus 로고    scopus 로고
    • Mesial temporal lobe epilepsy: A proton magnetic resonance spectroscopy study and a histopathological analysis
    • Cohen-Gadol AA, Pan JW, Kim JH, Spencer DD, Hetherington HH. Mesial temporal lobe epilepsy: A proton magnetic resonance spectroscopy study and a histopathological analysis. J. Neurosurg. 101(4), 613-620 (2004).
    • (2004) J. Neurosurg. , vol.101 , Issue.4 , pp. 613-620
    • Cohen-Gadol, A.A.1    Pan, J.W.2    Kim, J.H.3    Spencer, D.D.4    Hetherington, H.H.5
  • 132
    • 0038434119 scopus 로고    scopus 로고
    • Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model
    • Borges K, Gearing M, McDermott DL et al. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Exp. Neurol. 182(1), 21-34 (2003).
    • (2003) Exp. Neurol. , vol.182 , Issue.1 , pp. 21-34
    • Borges, K.1    Gearing, M.2    McDermott, D.L.3
  • 133
    • 84877601668 scopus 로고    scopus 로고
    • Neuron-astrocyte signaling and epilepsy
    • Seifert G, Steinhauser C. Neuron-astrocyte signaling and epilepsy. Exp. Neurol. 244, 4-10 (2013).
    • (2013) Exp. Neurol. , vol.244 , Issue.4-10
    • Seifert, G.1    Steinhauser, C.2
  • 134
    • 0013652589 scopus 로고    scopus 로고
    • Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances
    • Hinterkeuser S, Schroder W, Hager G et al. Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances. Eur. J. Neurosci. 12(6), 2087-2096 (2000).
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.6 , pp. 2087-2096
    • Hinterkeuser, S.1    Schroder, W.2    Hager, G.3
  • 135
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez-Hernandez A, Bell KP, Norenberg MD. Glutamine synthetase: Glial localization in brain. Science 195(4284), 1356-1358 (1977).
    • (1977) Science , vol.195 , Issue.4284 , pp. 1356-1358
    • Martinez-Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 137
    • 42149112453 scopus 로고    scopus 로고
    • Astrocytes in the epileptic brain
    • Wetherington J, Serrano G, Dingledine R. Astrocytes in the epileptic brain. Neuron 58(2), 168-178 (2008).
    • (2008) Neuron , vol.58 , Issue.2 , pp. 168-178
    • Wetherington, J.1    Serrano, G.2    Dingledine, R.3
  • 138
    • 33748518188 scopus 로고    scopus 로고
    • Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices
    • Fellin T, Gomez-Gonzalo M, Gobbo S, Carmignoto G, Haydon PG. Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices. J. Neurosci. 26(36), 9312-9322 (2006).
    • (2006) J. Neurosci. , vol.26 , Issue.36 , pp. 9312-9322
    • Fellin, T.1    Gomez-Gonzalo, M.2    Gobbo, S.3    Carmignoto, G.4    Haydon, P.G.5
  • 139
    • 0000926233 scopus 로고    scopus 로고
    • Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy
    • Aronica E, van Vliet EA, Mayboroda OA, Troost D, da Silva FHL, Gorter JA. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur. J. Neurosci. 12(7), 2333-2344 (2000).
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.7 , pp. 2333-2344
    • Aronica, E.1    Van Vliet, E.A.2    Mayboroda, O.A.3    Troost, D.4    Silva Fhl, D.5    Gorter, J.A.6
  • 140
    • 84862330058 scopus 로고    scopus 로고
    • Astrocyte calcium signaling and epilepsy
    • Carmignoto G, Haydon PG. Astrocyte calcium signaling and epilepsy. Glia 60(8), 1227-1233 (2012).
    • (2012) Glia , vol.60 , Issue.8 , pp. 1227-1233
    • Carmignoto, G.1    Haydon, P.G.2
  • 141
    • 77951721530 scopus 로고    scopus 로고
    • An excitatory loop with astrocytes contributes to drive neurons to seizure threshold
    • Gómez-Gonzalo M, Losi G, Chiavegato A et al. An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. PLoS Biol. 8(4), e1000352 (2010).
    • (2010) PLoS Biol. , vol.8 , Issue.4
    • Gómez-Gonzalo, M.1    Losi, G.2    Chiavegato, A.3
  • 142
    • 84877295694 scopus 로고    scopus 로고
    • Evolution of neuronal and astroglial disruption in the peri-contusional cortex of mice revealed by in vivo two-photon imaging
    • Sword J, Masuda T, Croom D, Kirov SA. Evolution of neuronal and astroglial disruption in the peri-contusional cortex of mice revealed by in vivo two-photon imaging. Brain 136(5), 1446-1461 (2013).
    • (2013) Brain , vol.136 , Issue.5 , pp. 1446-1461
    • Sword, J.1    Masuda, T.2    Croom, D.3    Kirov, S.A.4
  • 143
    • 84871488911 scopus 로고    scopus 로고
    • Purinergic 2Y1 receptor stimulation decreases cerebral edema and reactive gliosis in a traumatic brain injury model
    • Watts L, Sprague S, Zheng W et al. Purinergic 2Y1 receptor stimulation decreases cerebral edema and reactive gliosis in a traumatic brain injury model. J. Neurotrauma 30(1), 55-66 (2013).
    • (2013) J. Neurotrauma , vol.30 , Issue.1 , pp. 55-66
    • Watts, L.1    Sprague, S.2    Zheng, W.3
  • 144
    • 84878580322 scopus 로고    scopus 로고
    • ̀hit & run model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation
    • Ren Z, Iliff JJ, Yang L et al. ̀Hit & run model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. J. Cereb. Blood Flow Metab. 33, 834-845 (2013).
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , Issue.834-845
    • Ren, Z.1    Iliff, J.J.2    Yang, L.3
  • 145
    • 84873336945 scopus 로고    scopus 로고
    • Antagonism of purinergic signalling improves recovery from traumatic brain injury
    • Study that discovered that astrocytes exhibited ATP-induced Ca2+ waves after traumatic brain injury.
    • Choo AM, Miller WJ, Chen YC et al. Antagonism of purinergic signalling improves recovery from traumatic brain injury. Brain 136(1), 65-80 (2013). Study that discovered that astrocytes exhibited ATP-induced Ca2+ waves after traumatic brain injury.
    • (2013) Brain , vol.136 , Issue.1 , pp. 65-80
    • Choo, A.M.1    Miller, W.J.2    Chen, Y.C.3
  • 146
    • 2542481651 scopus 로고    scopus 로고
    • Contribution of glial cells to the development of amyloid plaques in Alzheimers disease
    • Nagele RG, Wegiel J, Venkataraman V, Imaki H, Wang KC, Wegiel J. Contribution of glial cells to the development of amyloid plaques in Alzheimers disease. Neurobiol. Aging 25(5), 663-674 (2004).
    • (2004) Neurobiol. Aging , vol.25 , Issue.5 , pp. 663-674
    • Nagele, R.G.1    Wegiel, J.2    Venkataraman, V.3    Imaki, H.4    Wang, K.C.5    Wegiel, J.6
  • 147
    • 47749113650 scopus 로고    scopus 로고
    • Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks
    • Kuchibhotla KV, Goldman ST, Lattarulo CR et al. Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron 59(2), 214-225 (2008).
    • (2008) Neuron , vol.59 , Issue.2 , pp. 214-225
    • Kuchibhotla, K.V.1    Goldman, S.T.2    Lattarulo, C.R.3
  • 148
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimers disease
    • Busche MA, Eichhoff G, Adelsberger H et al. Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimers disease. Science 321(5896), 1686-1689 (2008).
    • (2008) Science , vol.321 , Issue.5896 , pp. 1686-1689
    • Ma, B.1    Eichhoff, G.2    Adelsberger, H.3
  • 149
    • 84861844315 scopus 로고    scopus 로고
    • Critical role of soluble amyloid-b for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
    • Busche MA, Chen X, Henning HA et al. Critical role of soluble amyloid-b for early hippocampal hyperactivity in a mouse model of Alzheimer's disease. Proc. Natl Acad. Sci. USA 109(22), 8740-8745 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.22 , pp. 8740-8745
    • Ma, B.1    Chen, X.2    Henning, H.A.3
  • 150
    • 0038452658 scopus 로고    scopus 로고
    • Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity
    • Abramov AY, Canevari L, Duchen MR. Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. J. Neurosci. 23(12), 5088-5095 (2003).
    • (2003) J. Neurosci. , vol.23 , Issue.12 , pp. 5088-5095
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 151
    • 61349096009 scopus 로고    scopus 로고
    • Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
    • Study that discovered that astrocytes exhibit intercellular Ca2+ waves in vivo in a mouse Alzheimers disease model.
    • Kuchibhotla KV, Lattarulo CR, Hyman BT, Bacskai BJ. Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323(5918), 1211-1215 (2009). Study that discovered that astrocytes exhibit intercellular Ca2+ waves in vivo in a mouse Alzheimers disease model.
    • (2009) Science , vol.323 , Issue.5918 , pp. 1211-1215
    • Kuchibhotla, K.V.1    Lattarulo, C.R.2    Hyman, B.T.3    Bacskai, B.J.4
  • 152
    • 84870168829 scopus 로고    scopus 로고
    • S100B is increased in Parkinsons disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-a pathway
    • Sathe K, Maetzler W, Lang JD et al. S100B is increased in Parkinsons disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-a pathway. Brain 135(11), 3336-3347 (2012).
    • (2012) Brain , vol.135 , Issue.11 , pp. 3336-3347
    • Sathe, K.1    Maetzler, W.2    Lang, J.D.3
  • 153
    • 84870549095 scopus 로고    scopus 로고
    • Astrocyte-specific overexpression of nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model
    • Gan L, Vargas MR, Johnson DA, Johnson JA. Astrocyte-specific overexpression of nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J. Neurosci. 32(49), 17775-17787 (2012).
    • (2012) J. Neurosci. , vol.32 , Issue.49 , pp. 17775-17787
    • Gan, L.1    Vargas, M.R.2    Johnson, D.A.3    Johnson, J.A.4
  • 154
    • 84864398585 scopus 로고    scopus 로고
    • Subthalamic nucleus electrical stimulation modulates calcium activity of nigral astrocytes
    • Barat E, Boisseau S, Bouyssieres C, Appaix F, Savasta M, Albrieux M. Subthalamic nucleus electrical stimulation modulates calcium activity of nigral astrocytes. PLoS ONE 7(7), e41793 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Barat, E.1    Boisseau, S.2    Bouyssieres, C.3    Appaix, F.4    Savasta, M.5    Albrieux, M.6
  • 155
    • 77955089391 scopus 로고    scopus 로고
    • Targeting glial cells to elucidate the pathogenesis of Huntingtons disease
    • Hsiao HY, Chern Y. Targeting glial cells to elucidate the pathogenesis of Huntingtons disease. Mol. Neurobiol. 41(2-3), 248-255 (2010).
    • (2010) Mol. Neurobiol. , vol.41 , Issue.2-3 , pp. 248-255
    • Hsiao, H.Y.1    Chern, Y.2
  • 156
    • 84860870606 scopus 로고    scopus 로고
    • Adenoviral astrocyte-specific expression of BDNF in the striata of mice transgenic for Huntingtons disease delays the onset of the motor phenotype
    • Arregui L, Benitez J, Razgado L, Vergara P, Segovia J. Adenoviral astrocyte-specific expression of BDNF in the striata of mice transgenic for Huntingtons disease delays the onset of the motor phenotype. Cell Mol. Neurobiol. 31(8), 1229-1243 (2011).
    • (2011) Cell Mol. Neurobiol. , vol.31 , Issue.8 , pp. 1229-1243
    • Arregui, L.1    Benitez, J.2    Razgado, L.3    Vergara, P.4    Segovia, J.5
  • 157
    • 77956216040 scopus 로고    scopus 로고
    • Cholesterol defect is marked across multiple rodent models of Huntingtons disease and is manifest in astrocytes
    • Valenza M, Leoni V, Karasinska JM et al. Cholesterol defect is marked across multiple rodent models of Huntingtons disease and is manifest in astrocytes. J. Neurosci. 30(32), 10844-10850 (2010).
    • (2010) J. Neurosci. , vol.30 , Issue.32 , pp. 10844-10850
    • Valenza, M.1    Leoni, V.2    Karasinska, J.M.3
  • 158
    • 77958156339 scopus 로고    scopus 로고
    • In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: A correlation with Huntingtons disease subjects
    • Faideau M, Kim J, Cormier K et al. In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: A correlation with Huntingtons disease subjects. Hum. Mol. Genet. 19(15), 3053-3067 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.15 , pp. 3053-3067
    • Faideau, M.1    Kim, J.2    Cormier, K.3
  • 159
    • 77951238141 scopus 로고    scopus 로고
    • Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice
    • Bradford J, Shin JY, Roberts M et al. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. J. Biol. Chem. 285(14), 10653-10661 (2010).
    • (2010) J. Biol. Chem. , vol.285 , Issue.14 , pp. 10653-10661
    • Bradford, J.1    Shin, J.Y.2    Roberts, M.3
  • 160
    • 84872027700 scopus 로고    scopus 로고
    • Excessive astrocyte-derived neurotrophin-3 contributes to the abnormal neuronal dendritic development in a mouse model of fragile X syndrome
    • Yang Q, Feng B, Zhang K et al. Excessive astrocyte-derived neurotrophin-3 contributes to the abnormal neuronal dendritic development in a mouse model of fragile X syndrome. PLoS Genet. 8(12), e1003172 (2012).
    • (2012) PLoS Genet. , vol.8 , Issue.12
    • Yang, Q.1    Feng, B.2    Zhang, K.3
  • 161
    • 80455158075 scopus 로고    scopus 로고
    • Probing astrocyte function in fragile X syndrome
    • Denman RB (Ed.). Springer, Berlin, Germany
    • Jacobs S, Cheng C, Doering L. Probing astrocyte function in fragile X syndrome. In: Modeling Fragile X Syndrome. Denman RB (Ed.). Springer, Berlin, Germany, 15-31 (2012).
    • (2012) Modeling Fragile X Syndrome , pp. 15-31
    • Jacobs, S.1    Cheng, C.2    Doering, L.3
  • 162
    • 84877084687 scopus 로고    scopus 로고
    • Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse
    • Higashimori H, Morel L, Huth J et al. Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse. Hum. Mol. Genet. 22(10), 2041-2054 (2013).
    • (2013) Hum. Mol. Genet. , vol.22 , Issue.10 , pp. 2041-2054
    • Higashimori, H.1    Morel, L.2    Huth, J.3
  • 163
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of disease: Astrocytes in neurodegenerative disease
    • Maragakis NJ, Rothstein JD. Mechanisms of disease: Astrocytes in neurodegenerative disease. Nat. Clin. Pract. Neuro. 2(12), 679-689 (2006).
    • (2006) Nat. Clin. Pract. Neuro. , vol.2 , Issue.12 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 164
    • 34247475338 scopus 로고    scopus 로고
    • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
    • Nagai M, Re DB, Nagata T et al. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat. Neurosci. 10(5), 615-622 (2007).
    • (2007) Nat. Neurosci. , vol.10 , Issue.5 , pp. 615-622
    • Nagai, M.1    Re, D.B.2    Nagata, T.3
  • 165
    • 34247473080 scopus 로고    scopus 로고
    • Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
    • di Giorgio FP, Carrasco MA, Siao MC, Maniatis T, Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat. Neurosci. 10(5), 608-614 (2007).
    • (2007) Nat. Neurosci. , vol.10 , Issue.5 , pp. 608-614
    • Di Giorgio, F.P.1    Ma, C.2    Siao, M.C.3    Maniatis, T.4    Eggan, K.5
  • 166
    • 0025823978 scopus 로고
    • Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate
    • Charles AC, Merrill JE, Dirksen ER, Sandersont MJ. Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate. Neuron 6(6), 983-992 (1991).
    • (1991) Neuron , vol.6 , Issue.6 , pp. 983-992
    • Charles, A.C.1    Merrill, J.E.2    Dirksen, E.R.3    Sandersont, M.J.4
  • 168
    • 0037868094 scopus 로고    scopus 로고
    • Viral vectors for gene delivery to the nervous system
    • Davidson BL, Breakefield XO. Viral vectors for gene delivery to the nervous system. Nat. Rev. Neurosci. 4(5), 353-364 (2003).
    • (2003) Nat. Rev. Neurosci. , vol.4 , Issue.5 , pp. 353-364
    • Davidson, B.L.1    Breakefield, X.O.2
  • 170
    • 32944459983 scopus 로고    scopus 로고
    • Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and rh10 in the mouse brain
    • Cearley CN, Wolfe JH. Transduction Characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain. Mol. Ther. 13(3), 528-537 (2006).
    • (2006) Mol. Ther. , vol.13 , Issue.3 , pp. 528-537
    • Cearley, C.N.1    Wolfe, J.H.2
  • 171
    • 0034724209 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system
    • Davidson BL, Stein CS, Heth JA et al. Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system. Proc. Natl Acad. Sci. USA 97(7), 3428-3432 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.7 , pp. 3428-3432
    • Davidson, B.L.1    Stein, C.S.2    Heth, J.A.3
  • 172
    • 34548610909 scopus 로고    scopus 로고
    • A Single injection of an adeno-associated virus vector into nuclei with divergent connections results in widespread vector distribution in the brain and global correction of a neurogenetic disease
    • Cearley CN, Wolfe JH. A Single injection of an adeno-associated virus vector into nuclei with divergent connections results in widespread vector distribution in the brain and global correction of a neurogenetic disease. J. Neurosci. 27(37), 9928-9940 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.37 , pp. 9928-9940
    • Cearley, C.N.1    Wolfe, J.H.2
  • 173
    • 0034212887 scopus 로고    scopus 로고
    • Adeno-associated virus vectors: Activity and applications in the CNS
    • Peel AL, Klein RL. Adeno-associated virus vectors: Activity and applications in the CNS. J. Neurosci. Methods 98(2), 95-104 (2000).
    • (2000) J. Neurosci. Methods , vol.98 , Issue.2 , pp. 95-104
    • Peel, A.L.1    Klein, R.L.2
  • 174
    • 4344702714 scopus 로고    scopus 로고
    • Recombinant AAV-mediated gene delivery to the central nervous system
    • Tenenbaum L, Chtarto A, Lehtonen E et al. Recombinant AAV-mediated gene delivery to the central nervous system. J. Gene Med. 6(SUPPL. 1), S212-S222 (2004).
    • (2004) J. Gene Med. , vol.6 , Issue.SUPPL. 1
    • Tenenbaum, L.1    Chtarto, A.2    Lehtonen, E.3
  • 175
    • 70349850388 scopus 로고    scopus 로고
    • Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates
    • Lawlor PA, Bland RJ, Mouravlev A, Young D, During MJ. Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates. Mol. Ther. 17(10), 1692-1702 (2009).
    • (2009) Mol. Ther. , vol.17 , Issue.10 , pp. 1692-1702
    • Lawlor, P.A.1    Bland, R.J.2    Mouravlev, A.3    Young, D.4    During, M.J.5
  • 176
    • 16844373759 scopus 로고    scopus 로고
    • Control of calcium signal propagation to the mitochondria by inositol 1 4,5-trisphosphate-binding proteins
    • Lin X, Varnai P, Csordas G et al. Control of calcium signal propagation to the mitochondria by inositol 1,4,5-trisphosphate-binding proteins. J. Biol. Chem. 280(13), 12820-12832 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.13 , pp. 12820-12832
    • Lin, X.1    Varnai, P.2    Csordas, G.3
  • 177
    • 34548096154 scopus 로고    scopus 로고
    • Regulation of neurite growth by spontaneous Ca2+ oscillations in astrocytes
    • Kanemaru K, Okubo Y, Hirose K, Iino M. Regulation of neurite growth by spontaneous Ca2+ oscillations in astrocytes. J. Neurosci. 27(33), 8957-8966 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.33 , pp. 8957-8966
    • Kanemaru, K.1    Okubo, Y.2    Hirose, K.3    Iino, M.4
  • 178
    • 35548970311 scopus 로고    scopus 로고
    • Lentiviral vectors: Are they the future of animal transgenesis
    • Park F. Lentiviral vectors: Are they the future of animal transgenesis Physiol. Genomics 31(2), 159-173 (2007).
    • (2007) Physiol. Genomics , vol.31 , Issue.2 , pp. 159-173
    • Park, F.1
  • 179
    • 79851509664 scopus 로고    scopus 로고
    • Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra
    • Cannon JR, Sew T, Montero L, Burton EA, Greenamyre JT. Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra. Exp. Neurol. 228(1), 41-52 (2011).
    • (2011) Exp. Neurol. , vol.228 , Issue.1 , pp. 41-52
    • Cannon, J.R.1    Sew, T.2    Montero, L.3    Burton, E.A.4    Greenamyre, J.T.5
  • 180
    • 19944429120 scopus 로고    scopus 로고
    • Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo
    • Dittgen T, Nimmerjahn A, Komai S et al. Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proc. Natl Acad. Sci. USA 101(52), 18206-18211 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.52 , pp. 18206-18211
    • Dittgen, T.1    Nimmerjahn, A.2    Komai, S.3
  • 181
    • 64749092065 scopus 로고    scopus 로고
    • Engineered lentiviral vector targeting astrocytes in vivo
    • Colin Al, Faideau M, Dufour N et al. Engineered lentiviral vector targeting astrocytes in vivo. Glia 57(6), 667-679 (2009).
    • (2009) Glia , vol.57 , Issue.6 , pp. 667-679
    • Al, C.1    Faideau, M.2    Dufour, N.3
  • 182
    • 80053615483 scopus 로고    scopus 로고
    • Injection of recombinant adenovirus for delivery of genetically encoded calcium indicators into astrocytes of the cerebellar cortex Cold Spring Harb
    • Kuhn B, Hoogland TM, Wang SS. Injection of recombinant adenovirus for
    • (2011) Protoc. , vol.2011 , Issue.10 , pp. 1217-1223
    • Kuhn, B.1    Hoogland, T.M.2    Wang, S.S.3
  • 183
    • 78650131971 scopus 로고    scopus 로고
    • Optogenetic experimentation on astrocytes
    • Figueiredo M, Lane S, Tang F et al. Optogenetic experimentation on astrocytes. Exp. Physiol. 96(1), 40-50 (2011).
    • (2011) Exp. Physiol. , vol.96 , Issue.1 , pp. 40-50
    • Figueiredo, M.1    Lane, S.2    Tang, F.3
  • 184
    • 33749233855 scopus 로고    scopus 로고
    • Astrocytic expression of transgene in the rat brain mediated by baculovirus vectors containing an astrocyte-specific promoter
    • Wang CY , Wang S. Astrocytic expression of transgene in the rat brain mediated by baculovirus vectors containing an astrocyte-specific promoter. Gene Ther. 13(20), 1447-1456 (2006).
    • (2006) Gene Ther. , vol.13 , Issue.20 , pp. 1447-1456
    • Wang, C.Y.1    Wang, S.2
  • 185
    • 50849123433 scopus 로고    scopus 로고
    • A genetically encoded calcium indicator for chronic in vivo two-photon imaging
    • Mank M, Santos AF, Direnberger S et al. A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nat. Meth. 5(9), 805-811 (2008).
    • (2008) Nat. Meth. , vol.5 , Issue.9 , pp. 805-811
    • Mank, M.1    Santos, A.F.2    Direnberger, S.3
  • 186
    • 77951667651 scopus 로고    scopus 로고
    • Selective induction of astrocytic gliosis generates deficits in neuronal inhibition
    • Ortinski PI, Dong J, Mungenast A et al. Selective induction of astrocytic gliosis generates deficits in neuronal inhibition. Nat. Neurosci. 13(5), 584-591 (2010).
    • (2010) Nat. Neurosci. , vol.13 , Issue.5 , pp. 584-591
    • Ortinski, P.I.1    Dong, J.2    Mungenast, A.3
  • 187
    • 79961032418 scopus 로고    scopus 로고
    • Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system
    • Zhang H, Yang B, Mu X et al. Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system. Mol. Ther. 19(8), 1440-1448 (2011).
    • (2011) Mol. Ther. , vol.19 , Issue.8 , pp. 1440-1448
    • Zhang, H.1    Yang, B.2    Mu, X.3
  • 188
    • 67649861393 scopus 로고    scopus 로고
    • Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons
    • Duque S, Joussemet B, Riviere C et al. Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons. Mol. Ther. 17(7), 1187-1196 (2009).
    • (2009) Mol. Ther. , vol.17 , Issue.7 , pp. 1187-1196
    • Duque, S.1    Joussemet, B.2    Riviere, C.3
  • 190
    • 77950257476 scopus 로고    scopus 로고
    • NMDA receptors activated by subventricular zone astrocytic glutamate are critical for neuroblast survival prior to entering a synaptic network
    • Platel JC, Dave KA, Gordon V, Lacar B, Rubio ME, Bordey A. NMDA receptors activated by subventricular zone astrocytic glutamate are critical for neuroblast survival prior to entering a synaptic network. Neuron 65(6), 859-872 (2010).
    • (2010) Neuron , vol.65 , Issue.6 , pp. 859-872
    • Platel, J.C.1    Dave, K.A.2    Gordon, V.3    Lacar, B.4    Rubio, M.E.5    Bordey, A.6
  • 191
    • 83555178063 scopus 로고    scopus 로고
    • Imaging and recording subventricular zone progenitor cells in live tissue of postnatal mice
    • Lacar B, Young SZ, Platel JC, Bordey A. Imaging and recording subventricular zone progenitor cells in live tissue of postnatal mice. Front. Neurosci. 4, 43 (2010).
    • (2010) Front. Neurosci. , vol.4 , Issue.43
    • Lacar, B.1    Young, S.Z.2    Platel, J.C.3    Bordey, A.4
  • 192
    • 21844436786 scopus 로고    scopus 로고
    • Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1 4,5-trisphosphate(IP3)-receptor type 2-deficient mice
    • Li X, Zima AV, Sheikh F, Blatter LA, Chen J. Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice. Circ. Res. 96(12), 1274-1281 (2005).
    • (2005) Circ. Res. , vol.96 , Issue.12 , pp. 1274-1281
    • Li, X.1    Zima, A.V.2    Sheikh, F.3    Blatter, L.A.4    Chen, J.5
  • 193
    • 84876415041 scopus 로고    scopus 로고
    • P2Y1R-initiated IP3R-dependent stimulation of astrocyte mitochondrial metabolism reduces and partially reverses ischemic neuronal damage in mouse
    • Zheng W, Talley Watts L, Holstein DM, Wewer J, Lechleiter JD. P2Y1R-initiated, IP3R-dependent stimulation of astrocyte mitochondrial metabolism reduces and partially reverses ischemic neuronal damage in mouse. J. Cereb. Blood Flow Metab. 33(4), 600-611 (2013).
    • (2013) J. Cereb Blood Flow Metab. , vol.33 , Issue.4 , pp. 600-611
    • Zheng, W.1    Talley Watts, L.2    Holstein, D.M.3    Wewer, J.4    Lechleiter, J.D.5
  • 194
    • 84879340566 scopus 로고    scopus 로고
    • Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia
    • Dong QP, He JQ, Chai Z. Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia. Neurobiol. Dis. 58(0), 68-75 (2013).
    • (2013) Neurobiol. Dis. , vol.58 , Issue.0 , pp. 68-75
    • Dong, Q.P.1    He, J.Q.2    Chai, Z.3
  • 195
    • 58549112040 scopus 로고    scopus 로고
    • Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss
    • Halassa MM, Florian C, Fellin T et al. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron 61(2), 213-219 (2009).
    • (2009) Neuron , vol.61 , Issue.2 , pp. 213-219
    • Halassa, M.M.1    Florian, C.2    Fellin, T.3
  • 196
    • 84880299450 scopus 로고    scopus 로고
    • Astrocyte-derived ATP modulates depressive-like behaviors
    • Cao X, Li LP, Wang Q et al. Astrocyte-derived ATP modulates depressive-like behaviors. Nat. Med. 19(6), 773-777 (2013).
    • (2013) Nat. Med. , vol.19 , Issue.6 , pp. 773-777
    • Cao, X.1    Li, L.P.2    Wang, Q.3
  • 197
    • 84874614806 scopus 로고    scopus 로고
    • Inhibition of a SNARE-sensitive pathway in astrocytes attenuates damage following stroke
    • Hines DJ, Haydon PG. Inhibition of a SNARE-sensitive pathway in astrocytes attenuates damage following stroke. J. Neurosci. 33(10), 4234-4240 (2013).
    • (2013) J. Neurosci. , vol.33 , Issue.10 , pp. 4234-4240
    • Hines, D.J.1    Haydon, P.G.2
  • 198
    • 0031722020 scopus 로고    scopus 로고
    • Using knockout and transgenic mice to study neurophysiology and behavior
    • Picciotto MR, Wickman K. Using knockout and transgenic mice to study neurophysiology and behavior. Physiol. Rev. 78(4), 1131-1163 (1998).
    • (1998) Physiol. Rev. , vol.78 , Issue.4 , pp. 1131-1163
    • Picciotto, M.R.1    Wickman, K.2
  • 199
    • 33745532487 scopus 로고    scopus 로고
    • Inducible gene deletion in astroglia and radial glia - A valuable tool for functional and lineage analysis
    • Mori T, Tanaka K, Buffo A, Wurst W, Kuhn R, Gotz M. Inducible gene deletion in astroglia and radial glia - a valuable tool for functional and lineage analysis. Glia 54(1), 21-34 (2006).
    • (2006) Glia , vol.54 , Issue.1 , pp. 21-34
    • Mori, T.1    Tanaka, K.2    Buffo, A.3    Wurst, W.4    Kuhn, R.5    Gotz, M.6
  • 200
    • 0035584249 scopus 로고    scopus 로고
    • Efficient gene transfer into the embryonic mouse brain using in vivo electroporation
    • Saito T, Nakatsuji N. Efficient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev. Biol. 240(1), 237-246 (2001).
    • (2001) Dev. Biol. , vol.240 , Issue.1 , pp. 237-246
    • Saito, T.1    Nakatsuji, N.2
  • 201
    • 0035798089 scopus 로고    scopus 로고
    • Neocortex patterning by the secreted signaling molecule FGF8
    • Fukuchi-Shimogori T, Grove EA. Neocortex patterning by the secreted signaling molecule FGF8. Science 294(5544), 1071-1074 (2001).
    • (2001) Science , vol.294 , Issue.5544 , pp. 1071-1074
    • Fukuchi-Shimogori, T.1    Grove, E.A.2
  • 202
    • 0035804770 scopus 로고    scopus 로고
    • Efficient in utero gene transfer system to the developing mouse brain using electroporation: Visualization of neuronal migration in the developing cortex
    • Tabata H , Nakajima K. Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex. Neuroscience 103(4), 865-872 (2001).
    • (2001) Neuroscience , vol.103 , Issue.4 , pp. 865-872
    • Tabata, H.1    Nakajima, K.2
  • 203
    • 69449103616 scopus 로고    scopus 로고
    • New and improved tools for in utero electroporation studies of developing cerebral cortex
    • LoTurco J, Manent JB, Sidiqi F. New and improved tools for in utero electroporation studies of developing cerebral cortex. Cerebral Cortex 19(SUPPL. 1), i120-i125 (2009).
    • (2009) Cerebral Cortex , vol.19 , Issue.SUPPL. 1
    • Loturco, J.1    Manent, J.B.2    Sidiqi, F.3
  • 204
    • 84877248445 scopus 로고    scopus 로고
    • Clonal identity determines astrocyte cortical heterogeneity
    • Garcia-Marques J, Lopez-Mascaraque L. Clonal identity determines astrocyte cortical heterogeneity. Cerebral Cortex 23(6), 1463-1472 (2013).
    • (2013) Cerebral Cortex , vol.23 , Issue.6 , pp. 1463-1472
    • Garcia-Marques, J.1    Lopez-Mascaraque, L.2
  • 206
    • 33749026335 scopus 로고    scopus 로고
    • Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
    • Rust MJ, Bates M, Zhuang X. Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat. Meth. 3(10), 793-796 (2006).
    • (2006) Nat. Meth. , vol.3 , Issue.10 , pp. 793-796
    • Rust, M.J.1    Bates, M.2    Zhuang, X.3


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