Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia

Neurobiology of Disease

Volumn 58, Issue , 2013, Pages 68-75

  Dong, Qi Ping ^a   He, Jing Quan ^a   Chai, Zhen ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Astrocytic Ca2+ wave; Extrasynaptic NMDA receptor; Gap junction; Ischemia

Indexed keywords

CARBENOXOLONE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; INOSITOL TRISPHOSPHATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; DISEASE EXACERBATION; EXCITATION AND STIMULATION; HIPPOCAMPAL CA1 REGION; IONOTROPIC RECEPTOR STIMULATION; KNOCKOUT MOUSE; MICRODIALYSIS; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NONHUMAN; PHOTOLYSIS; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; SYNAPTIC TRANSMISSION;

ASTROCYTIC CA(2+) WAVE; EXTRASYNAPTIC NMDA RECEPTOR; GAP JUNCTION; ISCHEMIA;

ANIMALS; ASTROCYTES; BRAIN INJURIES; BRAIN ISCHEMIA; CALCIUM; CALCIUM SIGNALING; CHELATING AGENTS; DISEASE MODELS, ANIMAL; EGTAZIC ACID; EXCITATORY AMINO ACID AGENTS; FEMALE; GLUCOSE; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIALS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84879340566     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.05.005     Document Type: Article

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