GroEL/ES buffering and compensatory mutations promote protein evolution by stabilizing folding intermediates

Journal of Molecular Biology

Volumn 425, Issue 18, 2013, Pages 3403-3414

  Wyganowski, Kirsten T ^a   Kaltenbach, Miriam ^a   Tokuriki, Nobuhiko ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Chaperonins; Protein engineering; Protein evolution; Protein stability; Soluble functional expression

Indexed keywords

ARYLESTERASE; CHAPERONIN 60; PHOSPHOTRIESTERASE;

ARTICLE; ENZYME ACTIVITY; FITNESS; IN VITRO STUDY; LANDSCAPE; MOLECULAR EVOLUTION; MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STABILITY; THERMOSTABILITY;

EID: 84883283836     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.06.028     Document Type: Article

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