-
1
-
-
0015859467
-
Principles that govern the folding of protein chains
-
Anfinsen, C.B. Principles that govern the folding of protein chains. Science, 1973, 181, 223-230.
-
(1973)
Science
, vol.181
, pp. 223-230
-
-
Anfinsen, C.B.1
-
2
-
-
33749632462
-
Analysis of amyloid aggregates using agarose gel electrophoresis
-
Bagriantsev, S.; Kushnirov, V.V.; Liebman, S.W. Analysis of amyloid aggregates using agarose gel electrophoresis. Methods Enzymol., 2006, 412, 33-48.
-
(2006)
Methods Enzymol
, vol.412
, pp. 33-48
-
-
Bagriantsev, S.1
Kushnirov, V.V.2
Liebman, S.W.3
-
3
-
-
45449091418
-
Amyloidogenesis of natively unfolded proteins
-
Uversky, V.N. Amyloidogenesis of natively unfolded proteins. Curr. Alzheimer Res., 2008, 5, 260-287.
-
(2008)
Curr. Alzheimer Res
, vol.5
, pp. 260-287
-
-
Uversky, V.N.1
-
4
-
-
39349110541
-
Molecular mechanisms of polypeptide aggregation in human diseases
-
Khare, S.D.; Dokholyan, N.V. Molecular mechanisms of polypeptide aggregation in human diseases. Curr. Protein Pept. Sci., 2007, 8, 573-579.
-
(2007)
Curr. Protein Pept. Sci
, vol.8
, pp. 573-579
-
-
Khare, S.D.1
Dokholyan, N.V.2
-
5
-
-
0032493416
-
Temperature-controlled activity of DnaK-DnaJ-GrpE chaperones: Protein-folding arrest and recovery during and after heat-shock depends on substrate protein and GrpE concentration
-
Diamant, S.; Goloubinoff, P. Temperature-controlled activity of DnaK-DnaJ-GrpE chaperones: protein-folding arrest and recovery during and after heat-shock depends on substrate protein and GrpE concentration. Biochemistry, 1998, 37, 9688-9694.
-
(1998)
Biochemistry
, vol.37
, pp. 9688-9694
-
-
Diamant, S.1
Goloubinoff, P.2
-
6
-
-
0035478585
-
Macromolecular crowding: Obvious but underappreciated
-
Ellis, R.J. Macromolecular crowding: obvious but underappreciated. Trends Biochem. Sci., 2001, 26, 597-604.
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 597-604
-
-
Ellis, R.J.1
-
7
-
-
0026344818
-
Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli
-
Zimmerman, S.B.; Trach, S.O. Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli. J. Mol. Biol., 1991, 222, 599-620.
-
(1991)
J. Mol. Biol
, vol.222
, pp. 599-620
-
-
Zimmerman, S.B.1
Trach, S.O.2
-
8
-
-
0033573135
-
Identification of thermolabile E. coli proteins: Prevention and reversion of aggregation by DnaK and ClpB
-
Mogk, A.; Tomoyasu, T.; Goloubinoff, P.; Rüdiger, S.; Röder, D.; Langen, H.; Bukau, B. Identification of thermolabile E. coli proteins: prevention and reversion of aggregation by DnaK and ClpB. EMBO J., 1999, 18, 6934-6949.
-
(1999)
EMBO J
, vol.18
, pp. 6934-6949
-
-
Mogk, A.1
Tomoyasu, T.2
Goloubinoff, P.3
Rüdiger, S.4
Röder, D.5
Langen, H.6
Bukau, B.7
-
9
-
-
55949092886
-
α-Synuclein misfolding and neurodegenerative diseases
-
Uversky, V.N. α-Synuclein misfolding and neurodegenerative diseases. Curr. Protein Pept. Sci., 2008, 9, 507-540.
-
(2008)
Curr. Protein Pept. Sci
, vol.9
, pp. 507-540
-
-
Uversky, V.N.1
-
10
-
-
34347397758
-
Structure and function of a mitochondrial late embryogenesis abundant protein are revealed by desiccation
-
Tolleter, D.; Jaquinod, M.; Mangavel, C.; Passirani, C.; Saulnier, P.; Manon, S.; Teyssier, E.; Payet, N.; Avelange-Macherel, M.H.; Macherel, D. Structure and function of a mitochondrial late embryogenesis abundant protein are revealed by desiccation. Plant Cell, 2007, 19, 1580-1589.
-
(2007)
Plant Cell
, vol.19
, pp. 1580-1589
-
-
Tolleter, D.1
Jaquinod, M.2
Mangavel, C.3
Passirani, C.4
Saulnier, P.5
Manon, S.6
Teyssier, E.7
Payet, N.8
Avelange-Macherel, M.H.9
Macherel, D.10
-
11
-
-
34248595601
-
-
Esposito, A.; Dohm, C.P.; Kermer, P.; Bähr, M.; Wouters, F.S. alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton. Neurobiol. Dis., 2007, 26, 521-531.
-
Esposito, A.; Dohm, C.P.; Kermer, P.; Bähr, M.; Wouters, F.S. alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton. Neurobiol. Dis., 2007, 26, 521-531.
-
-
-
-
12
-
-
0037931741
-
Parkinson's disease-associated alpha-synuclein is a calmodulin substrate
-
Martinez, J.; Moeller, I.; Erdjument-Bromage, H.; Tempst, P.; Lauring, B. Parkinson's disease-associated alpha-synuclein is a calmodulin substrate. J. Biol. Chem., 2003, 278, 17379-17387.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 17379-17387
-
-
Martinez, J.1
Moeller, I.2
Erdjument-Bromage, H.3
Tempst, P.4
Lauring, B.5
-
13
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto, R.I. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev., 2008, 22, 1427-1438.
-
(2008)
Genes Dev
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
14
-
-
34147102801
-
Chaperones and proteases: Cellular fold-controlling factors of proteins in neurodegenerative diseases and aging
-
Hinault, M.P.; Ben-Zvi, A.; Goloubinoff, P. Chaperones and proteases: cellular fold-controlling factors of proteins in neurodegenerative diseases and aging. J. Mol. Neurosci., 2006, 30, 249-265.
-
(2006)
J. Mol. Neurosci
, vol.30
, pp. 249-265
-
-
Hinault, M.P.1
Ben-Zvi, A.2
Goloubinoff, P.3
-
15
-
-
0037147221
-
Proteinaceous infectious behavior in proteins is controlled by molecular chaperones
-
Ben-Zvi, A.P.; Goloubinoff, P. Proteinaceous infectious behavior in proteins is controlled by molecular chaperones. J. Biol. Chem., 2002, 277, 49422-49427.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 49422-49427
-
-
Ben-Zvi, A.P.1
Goloubinoff, P.2
-
16
-
-
43749102944
-
Masliah E. alpha-Synuclein aggregates interfere with parkin solubility and distribution: Role in the pathogenesis of Parkinson disease
-
Kawahara, K.; Hashimoto, M.; Bar-On, P.; Ho, G.J.; Crews, L.; Mizuno, H.; Rockenstein, E.; Imam, S.Z.; Masliah E. alpha-Synuclein aggregates interfere with parkin solubility and distribution: role in the pathogenesis of Parkinson disease. J. Biol. Chem., 2008, 283, 6979-6987.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 6979-6987
-
-
Kawahara, K.1
Hashimoto, M.2
Bar-On, P.3
Ho, G.J.4
Crews, L.5
Mizuno, H.6
Rockenstein, E.7
Imam, S.Z.8
-
17
-
-
38949181110
-
Neuropathology: Alzheimer's in real time
-
Masliah, E. Neuropathology: Alzheimer's in real time. Nature, 2008, 451, 638-639.
-
(2008)
Nature
, vol.451
, pp. 638-639
-
-
Masliah, E.1
-
18
-
-
33644850056
-
Progressive disruption of cellular protein folding in models of polyglutamine diseases
-
Gidalevitz, T.; Ben-Zvi, A.; Ho, K.H.; Brignull, H.R.; Morimoto, R.I. Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science, 2006, 311, 1471-1474.
-
(2006)
Science
, vol.311
, pp. 1471-1474
-
-
Gidalevitz, T.1
Ben-Zvi, A.2
Ho, K.H.3
Brignull, H.R.4
Morimoto, R.I.5
-
19
-
-
0033820092
-
Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies
-
Solary, E.; Droin, N.; Bettaieb, A.; Corcos, L.; Dimanche-Boitrel, M.T.; Garrido, C. Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies. Leukemia, 2000, 14, 1833-1849.
-
(2000)
Leukemia
, vol.14
, pp. 1833-1849
-
-
Solary, E.1
Droin, N.2
Bettaieb, A.3
Corcos, L.4
Dimanche-Boitrel, M.T.5
Garrido, C.6
-
20
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen, E.; Bieschke, J.; Perciavalle, R.M.; Kelly, J.W.; Dillin, A. Opposing activities protect against age-onset proteotoxicity. Science, 2000, 313, 1604-1610.
-
(2000)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
21
-
-
33750365052
-
Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?
-
Lashuel, H.A.; Lansbury, P.T.; Jr. Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins? Q. Rev. Biophys., 2006, 39, 167-201.
-
(2006)
Q. Rev. Biophys
, vol.39
, pp. 167-201
-
-
Lashuel, H.A.1
Lansbury Jr., P.T.2
-
22
-
-
44649091898
-
Heavy metal ions are potent inhibitors of protein folding
-
Sharma, S.K.; Goloubinoff, P.; Christen, P. Heavy metal ions are potent inhibitors of protein folding. Biochem. Biophys. Res. Commun., 2008, 372, 341-345.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.372
, pp. 341-345
-
-
Sharma, S.K.1
Goloubinoff, P.2
Christen, P.3
-
23
-
-
12144282992
-
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides
-
Huang, X.; Atwood, C.S.; Moir, R.D.; Hartshorn, M.A.; Tanzi, R.E.; Bush, A.I. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. J. Biol. Inorg. Chem., 2004, 9, 954-960.
-
(2004)
J. Biol. Inorg. Chem
, vol.9
, pp. 954-960
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Tanzi, R.E.5
Bush, A.I.6
-
24
-
-
31844433942
-
Environmental risk factors and the developmental-basis for Alzheimer's disease
-
Zawia, N.H.; Basha, M.R. Environmental risk factors and the developmental-basis for Alzheimer's disease. Rev. Neurosci., 2005, 16, 325-337.
-
(2005)
Rev. Neurosci
, vol.16
, pp. 325-337
-
-
Zawia, N.H.1
Basha, M.R.2
-
25
-
-
0034657229
-
Polyglutamine-induced ion channels: A possible mechanism for the neurotoxicity of Huntington and other CAG repeat diseases
-
Hirakura, Y.; Azimov, R.; Azimova, R.; Kagan, B.L. Polyglutamine-induced ion channels: a possible mechanism for the neurotoxicity of Huntington and other CAG repeat diseases. J. Neurosci. Res., 2000, 60, 490-494.
-
(2000)
J. Neurosci. Res
, vol.60
, pp. 490-494
-
-
Hirakura, Y.1
Azimov, R.2
Azimova, R.3
Kagan, B.L.4
-
26
-
-
33646126948
-
Membrane permeabilization: A common mechanism in protein misfolding diseases: If it look like a pore and acts like a pore, is it a pathogenic pore?
-
Lashuel, H.A. Membrane permeabilization: a common mechanism in protein misfolding diseases: If it look like a pore and acts like a pore, is it a pathogenic pore? Sci. Aging Knowledge Environ., 2005, 38, 28.
-
(2005)
Sci. Aging Knowledge Environ
, vol.38
, pp. 28
-
-
Lashuel, H.A.1
-
27
-
-
55949104903
-
Mechanism of alpha-synuclein oligomerization and membrane interaction: Theoretical approach to unstructured proteins studies
-
Tsigelny, I.F.; Sharikov, Y.; Miller, M.A.; Masliah, E. Mechanism of alpha-synuclein oligomerization and membrane interaction: theoretical approach to unstructured proteins studies. Nanomedicine, 2008, 4, 350-357.
-
(2008)
Nanomedicine
, vol.4
, pp. 350-357
-
-
Tsigelny, I.F.1
Sharikov, Y.2
Miller, M.A.3
Masliah, E.4
-
28
-
-
23044456332
-
Characterization of the aggregates formed during recombinant protein expression in bacteria
-
Schrödel, A.; de Marco, A. Characterization of the aggregates formed during recombinant protein expression in bacteria. BMC Biochem., 2005, 6, 10.
-
(2005)
BMC Biochem
, vol.6
, pp. 10
-
-
Schrödel, A.1
de Marco, A.2
-
29
-
-
0032849874
-
-
LeVine, H, III, Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol., 1999, 309, 274-284.
-
LeVine, H, III, Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol., 1999, 309, 274-284.
-
-
-
-
30
-
-
7944233158
-
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
-
Selkoe, D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol., 2004, 6, 1054-1061.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
31
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito, R.R. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol., 2000, 10, 524-530.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
32
-
-
0024587074
-
Accumulation of abnormaly phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
Bancher, C.; Brunner, C.; Lassmann, H.; Budka, H.; Jellinger, K.; Wiche, G.; Seitelberger, F.; Grundke-Iqbal, I.; Iqbal, K.; Wisniewski, H.M. Accumulation of abnormaly phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res., 1989, 477, 90-99.
-
(1989)
Brain Res
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, I.8
Iqbal, K.9
Wisniewski, H.M.10
-
33
-
-
2942667812
-
Immunohistochemical study of tau accumulation in early stages of Alzheimer-type neurofibrillary lesions
-
Togo, T.; Akiyama, H.; Iseki, E.; Uchikado, H.; Kondo, H.; Ikeda, K.; Tsuchiya, K.; de Silva, R.; Lees, A.; Kosaka, K. Immunohistochemical study of tau accumulation in early stages of Alzheimer-type neurofibrillary lesions. Acta Neuropathol., 2004, 107, 504-508.
-
(2004)
Acta Neuropathol
, vol.107
, pp. 504-508
-
-
Togo, T.1
Akiyama, H.2
Iseki, E.3
Uchikado, H.4
Kondo, H.5
Ikeda, K.6
Tsuchiya, K.7
de Silva, R.8
Lees, A.9
Kosaka, K.10
-
34
-
-
0029906304
-
Retinitis pigmentosa: Unfolding its mystery
-
Berson, E.L. Retinitis pigmentosa: unfolding its mystery. Proc. Natl. Acad. Sci. USA, 1996, 93, 4526-4528.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4526-4528
-
-
Berson, E.L.1
-
35
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev, A.F.; Goldberg, A.L. Proteasome inhibitors: from research tools to drug candidates. Chem. Biol., 2001, 8, 739-758.
-
(2001)
Chem. Biol
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
36
-
-
0028138240
-
Structure and function in rhodopsin: Requirements of a specific structure for the intradiscal domain
-
Anukanth, A.; Khorana, H.G. Structure and function in rhodopsin: requirements of a specific structure for the intradiscal domain. J. Biol. Chem., 1994, 269, 19738-19744.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 19738-19744
-
-
Anukanth, A.1
Khorana, H.G.2
-
37
-
-
33745167938
-
Protein misfolding diseases and chaperone based therapeutic approaches
-
Chaudhuri, T.K.; Paul, S. Protein misfolding diseases and chaperone based therapeutic approaches. FEBS J., 2006, 273, 1331-1349.
-
(2006)
FEBS J
, vol.273
, pp. 1331-1349
-
-
Chaudhuri, T.K.1
Paul, S.2
-
38
-
-
0035955743
-
Chemical chaperones regulate molecular chaperones in vitro and in cells under combined salt and heat stresses
-
Diamant, S.; Eliahu, N.; Rosenthal, D.; Goloubinoff, P. Chemical chaperones regulate molecular chaperones in vitro and in cells under combined salt and heat stresses. J. Biol. Chem., 2001, 276, 39586-39591.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 39586-39591
-
-
Diamant, S.1
Eliahu, N.2
Rosenthal, D.3
Goloubinoff, P.4
-
39
-
-
0037487260
-
Dicarboxylic amino acids and glycine-betaine regulate chaperone-mediated protein-disaggregation under stress
-
Diamant, S.; Rosenthal, D.; Azem, A.; Eliahu, N.; Ben-Zvi, A.P.; Goloubinoff, P. Dicarboxylic amino acids and glycine-betaine regulate chaperone-mediated protein-disaggregation under stress. Mol. Microbiol., 2003, 49, 401-410.
-
(2003)
Mol. Microbiol
, vol.49
, pp. 401-410
-
-
Diamant, S.1
Rosenthal, D.2
Azem, A.3
Eliahu, N.4
Ben-Zvi, A.P.5
Goloubinoff, P.6
-
40
-
-
30144445464
-
Abiotic stress, the field environment and stress combination
-
Mittler, R. Abiotic stress, the field environment and stress combination. Trends Plant Sci. 2006, 11, 15-19.
-
(2006)
Trends Plant Sci
, vol.11
, pp. 15-19
-
-
Mittler, R.1
-
41
-
-
0032983061
-
In vivo chaperone activity of heat shock protein 70 and thermotolerance
-
Nollen, E.A.; Brunsting, J.F.; Roelofsen, H.; Weber, L.A.; Kampinga, H.H. In vivo chaperone activity of heat shock protein 70 and thermotolerance. Mol. Cell. Biol., 11991, 9, 2069-2079.
-
(1991)
Mol. Cell. Biol
, vol.1
, Issue.9
, pp. 2069-2079
-
-
Nollen, E.A.1
Brunsting, J.F.2
Roelofsen, H.3
Weber, L.A.4
Kampinga, H.H.5
-
42
-
-
33750996168
-
Keep the traffic moving: Mechanism of the Hsp70 motor
-
Sousa, R.; Lafer, E.M. Keep the traffic moving: mechanism of the Hsp70 motor. Traffic, 2006, 7, 1596-1603.
-
(2006)
Traffic
, vol.7
, pp. 1596-1603
-
-
Sousa, R.1
Lafer, E.M.2
-
43
-
-
34548292474
-
Enhanced Hsp70 expression alters IB kinase proteasomal degradation in experimental ARDS
-
Weiss, Y.G.; Bromberg, Z.; Raj, N.; Raphael, J.; Goloubinoff, P.; Ben-Neriah, Y.; Deutschman, C.S. Enhanced Hsp70 expression alters IB kinase proteasomal degradation in experimental ARDS. Crit. Care Med., 2007, 35, 2128-2138.
-
(2007)
Crit. Care Med
, vol.35
, pp. 2128-2138
-
-
Weiss, Y.G.1
Bromberg, Z.2
Raj, N.3
Raphael, J.4
Goloubinoff, P.5
Ben-Neriah, Y.6
Deutschman, C.S.7
-
44
-
-
19644387113
-
Evidence for regulation of ER/Golgi. SNARE complex formation by HSC 70 chaperones
-
Joglekar, A.P.; Hay, J.C. Evidence for regulation of ER/Golgi. SNARE complex formation by HSC 70 chaperones. Eur. J. Cell Biol., 2005, 84, 529-542.
-
(2005)
Eur. J. Cell Biol
, vol.84
, pp. 529-542
-
-
Joglekar, A.P.1
Hay, J.C.2
-
45
-
-
33746705661
-
Chaperoning steroid hormone action
-
Picard, D. Chaperoning steroid hormone action. Trends Endocrinol. Metab., 2006, 17, 229-235.
-
(2006)
Trends Endocrinol. Metab
, vol.17
, pp. 229-235
-
-
Picard, D.1
-
46
-
-
84934440933
-
Chaperone regulation of the heat shock protein response
-
Voellmy, R.; Boellmann, F. Chaperone regulation of the heat shock protein response. Adv. Exp. Med. Biol., 2007, 594, 89-99.
-
(2007)
Adv. Exp. Med. Biol
, vol.594
, pp. 89-99
-
-
Voellmy, R.1
Boellmann, F.2
-
47
-
-
34249693697
-
Requirements for a conservative protein translocation pathway in chloroplasts
-
Vojta, L.; Soll, J.; Bölter, B. Requirements for a conservative protein translocation pathway in chloroplasts. FEBS Lett., 2007, 581, 2621-2624.
-
(2007)
FEBS Lett
, vol.581
, pp. 2621-2624
-
-
Vojta, L.1
Soll, J.2
Bölter, B.3
-
48
-
-
36749001066
-
Protein translocation across the eukaryotic ER and bacterial plasma membranes
-
Rapoport, T.A. Protein translocation across the eukaryotic ER and bacterial plasma membranes. Nature, 2007, 450, 663-669.
-
(2007)
Nature
, vol.450
, pp. 663-669
-
-
Rapoport, T.A.1
-
49
-
-
0034328890
-
Protein unfolding by mitochondria: The Hsp70. import motor
-
Matouschek, A.; Pfanner, N.; Voos, W. Protein unfolding by mitochondria: the Hsp70. import motor. EMBO Rep., 2000, 1, 404-410.
-
(2000)
EMBO Rep
, vol.1
, pp. 404-410
-
-
Matouschek, A.1
Pfanner, N.2
Voos, W.3
-
50
-
-
42149106909
-
Hsp27 regulates proinflammatory mediator release in keratinocytes by modulating NFkappaB signaling
-
Sur, R.; Lyte, P.A.; Southall, M.D. Hsp27 regulates proinflammatory mediator release in keratinocytes by modulating NFkappaB signaling. J. Invest. Dermatol., 2008, 128, 1116-1122.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1116-1122
-
-
Sur, R.1
Lyte, P.A.2
Southall, M.D.3
-
51
-
-
37549033478
-
Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome
-
Bromberg, Z.; Raj, N.; Goloubinoff, P.; Deutschman, C.S.; Weiss, Y.G. Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome. Crit. Care Med., 2008, 36, 246-255.
-
(2008)
Crit. Care Med
, vol.36
, pp. 246-255
-
-
Bromberg, Z.1
Raj, N.2
Goloubinoff, P.3
Deutschman, C.S.4
Weiss, Y.G.5
-
52
-
-
33846682590
-
Heat shock protein 70 increases tumorgenicity and inhibits apoptosis in pancreatic adenocarcinoma
-
Aghdassi, A.; Phillips, P.; Dudeja, V.; Dhaulakhandi, D.; Sharif, R.; Dawra, R.; Lerch, M.M.; Saluja, A. Heat shock protein 70 increases tumorgenicity and inhibits apoptosis in pancreatic adenocarcinoma. Cancer Res., 2007, 67, 616-625.
-
(2007)
Cancer Res
, vol.67
, pp. 616-625
-
-
Aghdassi, A.1
Phillips, P.2
Dudeja, V.3
Dhaulakhandi, D.4
Sharif, R.5
Dawra, R.6
Lerch, M.M.7
Saluja, A.8
-
53
-
-
34547726143
-
The role of stress proteins in prostate cancer
-
So, A.; Hadaschik, B.; Sowery, R.; Gleave, M. The role of stress proteins in prostate cancer. Curr. Genomics, 2007, 8, 252-261.
-
(2007)
Curr. Genomics
, vol.8
, pp. 252-261
-
-
So, A.1
Hadaschik, B.2
Sowery, R.3
Gleave, M.4
-
54
-
-
35548939457
-
Heat shock proteins and protection of the nervous system
-
Brown, I.R. Heat shock proteins and protection of the nervous system. Ann. N. Y. Acad. Sci., 2007, 1113, 147-158.
-
(2007)
Ann. N. Y. Acad. Sci
, vol.1113
, pp. 147-158
-
-
Brown, I.R.1
-
55
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
Horwitz, J. Alpha-crystallin can function as a molecular chaperone. Proc. Natl. Acad. Sci. USA, 1992, 89, 10449-10453.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
56
-
-
0032924953
-
Hsp90 & Co. - a holding for folding
-
Buchner, J. Hsp90 & Co. - a holding for folding. Trends Biochem. Sci., 1999, 24, 136-141.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 136-141
-
-
Buchner, J.1
-
57
-
-
0030461621
-
Chaperone activity and structure of monomeric polypeptide binding domains of GroEL
-
Zahn, R.; Buckle, A.M.; Perrett, S.; Johnson, C.M.; Corrales, F.J.; Golbik R.; Fersht, A.R. Chaperone activity and structure of monomeric polypeptide binding domains of GroEL. Proc. Natl. Acad. Sci. USA, 1996, 93, 15024-15029.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15024-15029
-
-
Zahn, R.1
Buckle, A.M.2
Perrett, S.3
Johnson, C.M.4
Corrales, F.J.5
Golbik, R.6
Fersht, A.R.7
-
58
-
-
0343742639
-
Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation
-
Ehrnsperger, M.; Graber, S.; Gaestel, M.; Buchner, J. Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation. EMBO J., 1997, 16, 221-229.
-
(1997)
EMBO J
, vol.16
, pp. 221-229
-
-
Ehrnsperger, M.1
Graber, S.2
Gaestel, M.3
Buchner, J.4
-
59
-
-
0032079487
-
The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network
-
Veinger, L.; Diamant, S.; Buchner, J.; Goloubinoff, P. The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network. J. Biol. Chem., 1998, 273, 11032-11037.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 11032-11037
-
-
Veinger, L.1
Diamant, S.2
Buchner, J.3
Goloubinoff, P.4
-
60
-
-
0030965758
-
ATP-dependent proteases that also chaperone protein biogenesis
-
Suzuki, C.K.; Rep, M.; van Dijl, J.M.; Suda, K.; Grivell L.A.; Schatz, G. ATP-dependent proteases that also chaperone protein biogenesis. Trends Biochem. Sci., 1997, 22, 118-123.
-
(1997)
Trends Biochem. Sci
, vol.22
, pp. 118-123
-
-
Suzuki, C.K.1
Rep, M.2
van Dijl, J.M.3
Suda, K.4
Grivell, L.A.5
Schatz, G.6
-
61
-
-
41149142931
-
Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: From conformational changes to substrate translocation and processivity
-
Licht, S.; Lee, I. Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: from conformational changes to substrate translocation and processivity. Biochemistry, 2008, 47, 3595-3605.
-
(2008)
Biochemistry
, vol.47
, pp. 3595-3605
-
-
Licht, S.1
Lee, I.2
-
62
-
-
0033517351
-
Global unfolding of a substrate protein by the Hsp100 chaperone ClpA
-
Weber-Ban, E.U.; Reid, B.G.; Miranker, A.D.; Horwich, A.L. Global unfolding of a substrate protein by the Hsp100 chaperone ClpA. Nature, 1999, 401, 90-93.
-
(1999)
Nature
, vol.401
, pp. 90-93
-
-
Weber-Ban, E.U.1
Reid, B.G.2
Miranker, A.D.3
Horwich, A.L.4
-
63
-
-
0033176770
-
The base of the proteasome regulatory particle exhibits chaperone-like activity
-
Braun, B.C.; Glickman, M.; Kraft, R.; Dahlmann, B.; Kloetzel, P.M.; Finley, D.; Schmidt, M. The base of the proteasome regulatory particle exhibits chaperone-like activity. Nat. Cell Biol., 1999, 1, 221-226.
-
(1999)
Nat. Cell Biol
, vol.1
, pp. 221-226
-
-
Braun, B.C.1
Glickman, M.2
Kraft, R.3
Dahlmann, B.4
Kloetzel, P.M.5
Finley, D.6
Schmidt, M.7
-
64
-
-
25844525796
-
Cellular functions, mechanism of action, and regulation of FtsH protease
-
Ito, K.; Akiyama, Y. Cellular functions, mechanism of action, and regulation of FtsH protease. Annu. Rev. Microbiol., 2005, 59, 211-231.
-
(2005)
Annu. Rev. Microbiol
, vol.59
, pp. 211-231
-
-
Ito, K.1
Akiyama, Y.2
-
65
-
-
0024439338
-
Demonstration by genetic suppression of interaction of GroE products with many proteins
-
Van Dyk, T.K.; Gatenby, A.A.; LaRossa, R.A. Demonstration by genetic suppression of interaction of GroE products with many proteins. Nature, 1989, 342, 451-453.
-
(1989)
Nature
, vol.342
, pp. 451-453
-
-
Van Dyk, T.K.1
Gatenby, A.A.2
LaRossa, R.A.3
-
66
-
-
35748962910
-
The HSP 70 chaperone machines of Escherichia coli: A paradigm for the repartition of chaperone functions
-
Genevaux, P.; Georgopoulos, C.; Kelley, W.L. The HSP 70 chaperone machines of Escherichia coli: a paradigm for the repartition of chaperone functions. Mol. Microbiol., 2007, 66, 840-857.
-
(2007)
Mol. Microbiol
, vol.66
, pp. 840-857
-
-
Genevaux, P.1
Georgopoulos, C.2
Kelley, W.L.3
-
67
-
-
11144243412
-
Modulation of neurodegeneration by molecular chaperones
-
Muchowski, P.J.; Wacker, J.L. Modulation of neurodegeneration by molecular chaperones. Nat. Rev. Neurosci., 2005, 6, 11-22.
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 11-22
-
-
Muchowski, P.J.1
Wacker, J.L.2
-
68
-
-
33646886633
-
-
Jiang, J.; Lafer, E.M.; Sousa, R. Crystallization of a functionally intact Hsc70 chaperone. Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun., 2006, 62, 39-43.
-
Jiang, J.; Lafer, E.M.; Sousa, R. Crystallization of a functionally intact Hsc70 chaperone. Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun., 2006, 62, 39-43.
-
-
-
-
69
-
-
0027426041
-
ATP-induced protein-Hsp70 complex dissociation requires K+ and does not involve ATP hydrolysis
-
Palleros, D.R.; Reid, K.L.; Shi, L.; Welch, W.J.; Fink A.L. ATP-induced protein-Hsp70 complex dissociation requires K+ and does not involve ATP hydrolysis. Nature, 1993, 365, 664-666.
-
(1993)
Nature
, vol.365
, pp. 664-666
-
-
Palleros, D.R.1
Reid, K.L.2
Shi, L.3
Welch, W.J.4
Fink, A.L.5
-
70
-
-
0028268243
-
Kinetics of molecular chaperone action
-
Schmid, D.; Baici, A.; Gehring H.; Christen, P. Kinetics of molecular chaperone action. Science, 1994, 263, 971-973.
-
(1994)
Science
, vol.263
, pp. 971-973
-
-
Schmid, D.1
Baici, A.2
Gehring, H.3
Christen, P.4
-
71
-
-
0033020519
-
Investigation of the interaction between DnaK and DnaJ by surface plasmon resonance
-
Mayer, M.P.; Laufen, T.; Paal, K.; McCarty, J.S.; Bukau, B. Investigation of the interaction between DnaK and DnaJ by surface plasmon resonance. J. Mol. Biol., 1999, 289, 1131-1144.
-
(1999)
J. Mol. Biol
, vol.289
, pp. 1131-1144
-
-
Mayer, M.P.1
Laufen, T.2
Paal, K.3
McCarty, J.S.4
Bukau, B.5
-
72
-
-
33845937366
-
Tuning of DnaK chaperone action by non-native-protein sensor DnaJ and thermosensor GrpE
-
Siegenthaler, R.K.; Christen, P. Tuning of DnaK chaperone action by non-native-protein sensor DnaJ and thermosensor GrpE. J. Biol. Chem., 2006, 281, 34448-34456.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 34448-34456
-
-
Siegenthaler, R.K.1
Christen, P.2
-
73
-
-
0031925150
-
Hsp70 Chaperone systems: Diversity of cellular functions and mechanism of action
-
Mayer, M.P.; Bukau, B. Hsp70 Chaperone systems: diversity of cellular functions and mechanism of action. Biol. Chem., 1998, 379, 261-268.
-
(1998)
Biol. Chem
, vol.379
, pp. 261-268
-
-
Mayer, M.P.1
Bukau, B.2
-
74
-
-
0033545978
-
Mechanism of regulation of Hsp70 chaperones by DnaJ co-chaperones
-
Laufen, T.; Mayer, M.P.; Beisel, C.; Klostermeier, D.; Mogk, A.; Reinstein J. and Bukau, B. Mechanism of regulation of Hsp70 chaperones by DnaJ co-chaperones. Proc. Natl. Acad. Sci. USA, 1999, 96, 5452-5457.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5452-5457
-
-
Laufen, T.1
Mayer, M.P.2
Beisel, C.3
Klostermeier, D.4
Mogk, A.5
Reinstein, J.6
Bukau, B.7
-
75
-
-
0037928428
-
Mechanism of the targeting action of DnaJ in the DnaK molecular chaperone system
-
Han, W.; Christen, P. Mechanism of the targeting action of DnaJ in the DnaK molecular chaperone system. J. Biol. Chem., 2003, 278, 19038-19043.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19038-19043
-
-
Han, W.1
Christen, P.2
-
76
-
-
34547146401
-
The mechanism of Hsp70 Chaperones: (entropic) pulling the models together
-
Goloubinoff, P.; De Los Rios, P. The mechanism of Hsp70 Chaperones: (entropic) pulling the models together. Trends Biochem. Sci., 2007, 32, 372-380.
-
(2007)
Trends Biochem. Sci
, vol.32
, pp. 372-380
-
-
Goloubinoff, P.1
De Los Rios, P.2
-
77
-
-
0032503968
-
Hsp104, Hsp70 and Hsp40: A novel chaperone system that rescues previously aggregated proteins
-
Glover, J.R.; Lindquist, S. Hsp104, Hsp70 and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell, 1998, 94, 73-82.
-
(1998)
Cell
, vol.94
, pp. 73-82
-
-
Glover, J.R.1
Lindquist, S.2
-
78
-
-
0033598703
-
Sequential mechanism of solubilization and refolding of stable protein aggregates by a bi-chaperone network
-
Goloubinoff, P.; Mogk, A.; Ben-Zvi, A.P.; Tomoyasu, T.; Bukau, B. Sequential mechanism of solubilization and refolding of stable protein aggregates by a bi-chaperone network. Proc. Natl. Acad. Sci. USA, 1999, 96, 13732-13737.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13732-13737
-
-
Goloubinoff, P.1
Mogk, A.2
Ben-Zvi, A.P.3
Tomoyasu, T.4
Bukau, B.5
-
79
-
-
0030976048
-
Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries
-
Rüdiger, S.; Germeroth, L.; Schneider-Mergener, J.; Bukau, B. Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries. EMBO J., 1997, 16, 1501-1507.
-
(1997)
EMBO J
, vol.16
, pp. 1501-1507
-
-
Rüdiger, S.1
Germeroth, L.2
Schneider-Mergener, J.3
Bukau, B.4
-
80
-
-
1842737657
-
cis-Effect of DnaJ on DnaK in ternary complexes with chimeric DnaK/DnaJ-binding peptides
-
Han, W.; Christen, P. cis-Effect of DnaJ on DnaK in ternary complexes with chimeric DnaK/DnaJ-binding peptides. FEBS Lett., 2004, 563, 146-150.
-
(2004)
FEBS Lett
, vol.563
, pp. 146-150
-
-
Han, W.1
Christen, P.2
-
81
-
-
0032564386
-
Sequence-specific rates of interaction of target peptides with the molecular chaperones DnaK and DnaJ
-
Pierpaoli, E.V.; Gisler, S.M.; Christen, P. Sequence-specific rates of interaction of target peptides with the molecular chaperones DnaK and DnaJ. Biochemistry 1998, 37, 16741-16748.
-
(1998)
Biochemistry
, vol.37
, pp. 16741-16748
-
-
Pierpaoli, E.V.1
Gisler, S.M.2
Christen, P.3
-
82
-
-
33646557371
-
Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling
-
De Los Rios, P.; Ben-Zvi, A.; Slutsky, O.; Azem, A.; Goloubinoff, P. Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling. Proc. Natl. Acad. Sci. USA, 2006, 103, 6166-6171.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6166-6171
-
-
De Los Rios, P.1
Ben-Zvi, A.2
Slutsky, O.3
Azem, A.4
Goloubinoff, P.5
-
83
-
-
0024456399
-
Polypeptide chain binding proteins - catalysts of protein folding and related processes in cells
-
Rothman, J.E. Polypeptide chain binding proteins - catalysts of protein folding and related processes in cells. Cell, 1989, 59, 591-601.
-
(1989)
Cell
, vol.59
, pp. 591-601
-
-
Rothman, J.E.1
-
84
-
-
0026006843
-
The role of heat-shock and chaperone proteins in protein folding: Possible molecular mechanisms
-
Hubbard, T.J.P.; Sander, C. The role of heat-shock and chaperone proteins in protein folding: Possible molecular mechanisms. Protein Eng., 1991, 4, 711-717.
-
(1991)
Protein Eng
, vol.4
, pp. 711-717
-
-
Hubbard, T.J.P.1
Sander, C.2
-
85
-
-
0035283043
-
Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone
-
Rüdiger, S.; Schneider-Mergener, J.; Bukau, B. Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone. EMBO J., 2001, 20, 1042-1050.
-
(2001)
EMBO J
, vol.20
, pp. 1042-1050
-
-
Rüdiger, S.1
Schneider-Mergener, J.2
Bukau, B.3
-
86
-
-
0029937037
-
Structural analysis of substrate binding by the molecular chaperone DnaK
-
Zhu, X.; Zhao, X.; Burkholder, W.F.; Gragerov, A.; Ogata, C.M.; Gottesman, M.E.; Hendrickson, W.A. Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 1996, 272, 1606-1614.
-
(1996)
Science
, vol.272
, pp. 1606-1614
-
-
Zhu, X.1
Zhao, X.2
Burkholder, W.F.3
Gragerov, A.4
Ogata, C.M.5
Gottesman, M.E.6
Hendrickson, W.A.7
-
87
-
-
0029094250
-
Divergent effects of ATP on the binding of the DnaK and DnaJ chaperones to each other, or to their various native and denatured protein substrates
-
Wawrzynów, A.; Zylicz, M. Divergent effects of ATP on the binding of the DnaK and DnaJ chaperones to each other, or to their various native and denatured protein substrates. J. Biol. Chem., 1995, 270, 19300-19306.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 19300-19306
-
-
Wawrzynów, A.1
Zylicz, M.2
-
88
-
-
0032524646
-
D-Peptide ligands for the co-chaperone DnaJ
-
Feifel, B.; Schönfeld, H.J.; Christen, P. D-Peptide ligands for the co-chaperone DnaJ. J. Biol. Chem., 1998, 273, 11999-12002.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 11999-12002
-
-
Feifel, B.1
Schönfeld, H.J.2
Christen, P.3
-
89
-
-
4444288866
-
Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual HSP70 chaperones
-
Ben-Zvi, A.; De Los Rios, P.; Dietler, G.; Goloubinoff, P. Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual HSP70 chaperones. J. Biol. Chem., 2004, 279, 37298-37303.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 37298-37303
-
-
Ben-Zvi, A.1
De Los Rios, P.2
Dietler, G.3
Goloubinoff, P.4
-
90
-
-
0036263966
-
The hsp70 chaperone DnaK is a secondary amide peptide bond cis-trans isomerase
-
Schiene-Fischer, C.; Habazettl, J.; Schmid, F.X.; Fischer, G. The hsp70 chaperone DnaK is a secondary amide peptide bond cis-trans isomerase. Nat. Struct. Biol., 2002, 9, 419-424.
-
(2002)
Nat. Struct. Biol
, vol.9
, pp. 419-424
-
-
Schiene-Fischer, C.1
Habazettl, J.2
Schmid, F.X.3
Fischer, G.4
-
91
-
-
0032546762
-
Catapult mechanism renders the chaperone action of Hsp70 unidirectional
-
Gisler, S.M.; Pierpaoli, E.V.; Christen, P. Catapult mechanism renders the chaperone action of Hsp70 unidirectional. J. Mol. Biol., 1998, 279, 833-840.
-
(1998)
J. Mol. Biol
, vol.279
, pp. 833-840
-
-
Gisler, S.M.1
Pierpaoli, E.V.2
Christen, P.3
-
92
-
-
0041026092
-
Interaction of Hsp70 chaperones with substrates
-
Rüdiger, S.; Buchberger, A.; Bukau, B. Interaction of Hsp70 chaperones with substrates. Nat. Struct. Biol., 1997, 4, 342-349.
-
(1997)
Nat. Struct. Biol
, vol.4
, pp. 342-349
-
-
Rüdiger, S.1
Buchberger, A.2
Bukau, B.3
-
93
-
-
0024578552
-
GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli
-
Goloubinoff, P.; Gatenby, A.A.; Lorimer, G.H. GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli. Nature, 1989, 337, 44-47.
-
(1989)
Nature
, vol.337
, pp. 44-47
-
-
Goloubinoff, P.1
Gatenby, A.A.2
Lorimer, G.H.3
-
94
-
-
33750000616
-
Folding on the chaperone: Yield enhancement through loose binding
-
Jewett, A.I.; Shea, J-E. Folding on the chaperone: Yield enhancement through loose binding. J. Mol. Biol., 2006, 363, 945-957.
-
(2006)
J. Mol. Biol
, vol.363
, pp. 945-957
-
-
Jewett, A.I.1
Shea, J.-E.2
-
95
-
-
0027391629
-
Small heat shock proteins are molecular chaperones
-
Jakob, U.; Gaestel, M.; Engel, K.; Buchner, J. Small heat shock proteins are molecular chaperones. J. Biol. Chem., 1993, 268, 1517-1520.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 1517-1520
-
-
Jakob, U.1
Gaestel, M.2
Engel, K.3
Buchner, J.4
-
96
-
-
0025727072
-
GroE facilitates refolding of citrate synthase by suppressing aggregation
-
Buchner, J.; Schmidt, M.; Fuchs, M.; Jaenicke, R.; Rudolph, R.; Schmid, F.; Kiefhaber, T. GroE facilitates refolding of citrate synthase by suppressing aggregation. Biochemistry, 1991, 30, 1586-1591.
-
(1991)
Biochemistry
, vol.30
, pp. 1586-1591
-
-
Buchner, J.1
Schmidt, M.2
Fuchs, M.3
Jaenicke, R.4
Rudolph, R.5
Schmid, F.6
Kiefhaber, T.7
-
97
-
-
0028940309
-
Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase-implications for heat shock in vivo
-
Jakob, U.; Lilie, H.; Meyer, I.; Buchner, J. Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase-implications for heat shock in vivo. J. Biol. Chem., 1995, 270, 7288-7294.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 7288-7294
-
-
Jakob, U.1
Lilie, H.2
Meyer, I.3
Buchner, J.4
-
98
-
-
0028832017
-
Cooperation of the molecular chaperone Ydj1 with specific Hsp70 homologs to suppress protein aggregation
-
Cyr, D.M. Cooperation of the molecular chaperone Ydj1 with specific Hsp70 homologs to suppress protein aggregation. FEBS Lett., 1995, 359, 129-132.
-
(1995)
FEBS Lett
, vol.359
, pp. 129-132
-
-
Cyr, D.M.1
-
99
-
-
56949083650
-
Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils
-
Arimon, M.; Grimminger, V.; Sanz, F.; Lashuel, H.A. Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils. J. Mol. Biol., 2008, 384, 1157-1173.
-
(2008)
J. Mol. Biol
, vol.384
, pp. 1157-1173
-
-
Arimon, M.1
Grimminger, V.2
Sanz, F.3
Lashuel, H.A.4
-
100
-
-
0034647887
-
Size-dependent disaggregation of aggregated protein particles by the DnaK chaperone machinery of Escherichia coli
-
Diamant, S.; Ben-Zvi, A.P.; Bukau, B.; Goloubinoff, P. Size-dependent disaggregation of aggregated protein particles by the DnaK chaperone machinery of Escherichia coli. J. Biol. Chem., 2000, 275, 21107-21113.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 21107-21113
-
-
Diamant, S.1
Ben-Zvi, A.P.2
Bukau, B.3
Goloubinoff, P.4
-
101
-
-
0035853131
-
Synechocystis hsp17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding
-
Török, Z.; Goloubinoff, P.; Horváth, I.; Tsvetkova, N.M.; Glatz, A.; Balogh, G.; Varvasovszki, V.; Los, D.A.; Vierling, E.; Crowe, J.H.; Vígh, L. Synechocystis hsp17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding. Proc. Natl. Acad. Sci. USA, 2001, 98, 3098-3103.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3098-3103
-
-
Török, Z.1
Goloubinoff, P.2
Horváth, I.3
Tsvetkova, N.M.4
Glatz, A.5
Balogh, G.6
Varvasovszki, V.7
Los, D.A.8
Vierling, E.9
Crowe, J.H.10
Vígh, L.11
-
102
-
-
0142125283
-
Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation
-
Mogk, A.; Deuerling, E.; Vorderwühlbecke, S.; Vierling, E.; Bukau, B. Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation. Mol. Microbiol., 2003, 50, 585-595.
-
(2003)
Mol. Microbiol
, vol.50
, pp. 585-595
-
-
Mogk, A.1
Deuerling, E.2
Vorderwühlbecke, S.3
Vierling, E.4
Bukau, B.5
-
103
-
-
0024820705
-
Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP
-
Goloubinoff, P.; Christeller, J.T.; Gatenby, A.A.; Lorimer, G.H. Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP. Nature, 1989, 342, 884-889.
-
(1989)
Nature
, vol.342
, pp. 884-889
-
-
Goloubinoff, P.1
Christeller, J.T.2
Gatenby, A.A.3
Lorimer, G.H.4
-
104
-
-
27644515982
-
Controlled expression of recombinant proteins in Physcomitrella Patens by a conditional heat-shock promoter: A tool for plant research and biotechnology
-
Saidi, Y.; Finka, A.; Zryd, J.P.; Schaefer, D.G.; Goloubinoff, P. Controlled expression of recombinant proteins in Physcomitrella Patens by a conditional heat-shock promoter: a tool for plant research and biotechnology. Plant Mol. Biol., 2005, 59, 695-709.
-
(2005)
Plant Mol. Biol
, vol.59
, pp. 695-709
-
-
Saidi, Y.1
Finka, A.2
Zryd, J.P.3
Schaefer, D.G.4
Goloubinoff, P.5
-
105
-
-
34247589657
-
Activation of the heat shock response in plants by chlorophenols: Transgenic Physcomitrella patens as a sensitive biosensor for organic pollutants
-
Saidi, Y.; Domini, M.; Choy, F.; Zryd, J.P.; Schwitzguebel, J.P.; Goloubinoff, P. Activation of the heat shock response in plants by chlorophenols: transgenic Physcomitrella patens as a sensitive biosensor for organic pollutants. Plant Cell Environ., 2007, 130, 753-763.
-
(2007)
Plant Cell Environ
, vol.130
, pp. 753-763
-
-
Saidi, Y.1
Domini, M.2
Choy, F.3
Zryd, J.P.4
Schwitzguebel, J.P.5
Goloubinoff, P.6
-
106
-
-
0035718677
-
Structure and function of the small heat shock protein α-crystallin family of molecular chaperones
-
Van Montfort, R.; Slingsby, C.; Vierling, E. Structure and function of the small heat shock protein α-crystallin family of molecular chaperones. Adv. Protein Chem., 2001, 59, 105-156.
-
(2001)
Adv. Protein Chem
, vol.59
, pp. 105-156
-
-
Van Montfort, R.1
Slingsby, C.2
Vierling, E.3
-
107
-
-
0028903455
-
The expanding small heat-shock protein family, and structure predictions of the conserved "alpha-crystallin domain
-
Caspers, G.-J.; Leunissen, J.A.M.; De Jong, W.W. The expanding small heat-shock protein family, and structure predictions of the conserved "alpha-crystallin domain". J. Mol. Evol., 1995, 40, 238-248.
-
(1995)
J. Mol. Evol
, vol.40
, pp. 238-248
-
-
Caspers, G.-J.1
Leunissen, J.A.M.2
De Jong, W.W.3
-
108
-
-
0036092428
-
Size matters: Of the small Hsp27 and its large oligomers
-
Garrido, C. Size matters: of the small Hsp27 and its large oligomers. Cell Death Differ., 2002, 9, 483-485.
-
(2002)
Cell Death Differ
, vol.9
, pp. 483-485
-
-
Garrido, C.1
-
109
-
-
0031934121
-
Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA
-
Litt, M.; Kramer, P.; LaMorticella, D.M.; Murphey, W.; Lovrien, E.W.; Weleber, R.G. Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA. Hum. Mol. Genet., 1998, 7, 471-474.
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 471-474
-
-
Litt, M.1
Kramer, P.2
LaMorticella, D.M.3
Murphey, W.4
Lovrien, E.W.5
Weleber, R.G.6
-
110
-
-
2642575701
-
Shocking degeneration
-
Benndorf, R.; Welsh, M.J. Shocking degeneration. Nat. Genet., 2004, 36, 547-548.
-
(2004)
Nat. Genet
, vol.36
, pp. 547-548
-
-
Benndorf, R.1
Welsh, M.J.2
-
111
-
-
17344361902
-
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy
-
Vicart, P.; Caron, A.; Guicheney, P.; Li, Z.; Prevost, M.C.; Faure, A.; Chateau, D.; Chapon, F.; Tome, F.; Dupret, J-M.; Paulin, D.; Fardeau, M. A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat. Genet. 1998, 20, 92-95.
-
(1998)
Nat. Genet
, vol.20
, pp. 92-95
-
-
Vicart, P.1
Caron, A.2
Guicheney, P.3
Li, Z.4
Prevost, M.C.5
Faure, A.6
Chateau, D.7
Chapon, F.8
Tome, F.9
Dupret, J.-M.10
Paulin, D.11
Fardeau, M.12
-
112
-
-
2642563501
-
-
Evgrafov, O.V.; Mersiyanova, I.; Irobi, J.; Van Den Bosch, L.; Dierick, I.; Leung, C.L.; Schagina, O.; Verpoorten, N.; Van Impe, K.; Fedotov, V.; Dadali, E.; Auer-Grumbach, M.; Windpassinger, C.; Wagner, K.; Mitrovic, Z.; Hilton-Jones, D.; Talbot, K.; Martin, J.J.; Vasserman, N.; Tverskaya, S.; Polyakov, A.; Liem, R.K.; Gettemans, J.; Robberecht, W.; De Jonghe, P.; Timmerman, V. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat. Genet., 2004, 36, 602-606.
-
Evgrafov, O.V.; Mersiyanova, I.; Irobi, J.; Van Den Bosch, L.; Dierick, I.; Leung, C.L.; Schagina, O.; Verpoorten, N.; Van Impe, K.; Fedotov, V.; Dadali, E.; Auer-Grumbach, M.; Windpassinger, C.; Wagner, K.; Mitrovic, Z.; Hilton-Jones, D.; Talbot, K.; Martin, J.J.; Vasserman, N.; Tverskaya, S.; Polyakov, A.; Liem, R.K.; Gettemans, J.; Robberecht, W.; De Jonghe, P.; Timmerman, V. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat. Genet., 2004, 36, 602-606.
-
-
-
-
113
-
-
2642539919
-
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy
-
Irobi, J.; Van Impe, K.; Seeman, P.; Jordanova, A.; Dierick, I.; Verpoorten, N.; Michalik, A.; De Vriendt, E.; Jacobs, A.; Gerwen, V.V. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat. Genet., 2004, 36, 597-601.
-
(2004)
Nat. Genet
, vol.36
, pp. 597-601
-
-
Irobi, J.1
Van Impe, K.2
Seeman, P.3
Jordanova, A.4
Dierick, I.5
Verpoorten, N.6
Michalik, A.7
De Vriendt, E.8
Jacobs, A.9
Gerwen, V.V.10
-
114
-
-
84934439863
-
The cellular "networking" of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis
-
Arrigo, A.P. The cellular "networking" of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis. Adv. Exp. Med. Biol., 2007, 594, 14-26.
-
(2007)
Adv. Exp. Med. Biol
, vol.594
, pp. 14-26
-
-
Arrigo, A.P.1
-
115
-
-
14044250859
-
Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels
-
Arrigo, A.P.; Virot, S.; Chaufour, S.; Firdaus, W.; Kretz-Remy, C.; Diaz-Latoud, C. Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels. Antioxid. Redox Signal, 2005, 7, 414-422.
-
(2005)
Antioxid. Redox Signal
, vol.7
, pp. 414-422
-
-
Arrigo, A.P.1
Virot, S.2
Chaufour, S.3
Firdaus, W.4
Kretz-Remy, C.5
Diaz-Latoud, C.6
-
116
-
-
0031918807
-
Chaperone-like properties
-
Horwitz, J.; Huang, Q.L.; Ding, L.; Bova, M.P. Lens alphacrystallin: Chaperone-like properties. Methods Enzymol., 1998, 290, 365-383.
-
(1998)
Methods Enzymol
, vol.290
, pp. 365-383
-
-
Horwitz, J.1
Huang, Q.L.2
Ding, L.3
Bova4
Lens alphacrystallin, M.P.5
-
117
-
-
0031024691
-
A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state
-
Lee, G.J.; Roseman, A.M.; Saibil, H.R.; Vierling, E. A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state. EMBO J., 1997, 16, 659-671.
-
(1997)
EMBO J
, vol.16
, pp. 659-671
-
-
Lee, G.J.1
Roseman, A.M.2
Saibil, H.R.3
Vierling, E.4
-
118
-
-
44849138934
-
Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments
-
Haslberger, T.; Zdanowicz, A.; Brand, I.; Kirstein, J.; Turgay, K.; Mogk, A.; Bukau, B. Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments. Nat. Struct. Mol. Biol., 2008, 15, 641-650.
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 641-650
-
-
Haslberger, T.1
Zdanowicz, A.2
Brand, I.3
Kirstein, J.4
Turgay, K.5
Mogk, A.6
Bukau, B.7
-
119
-
-
0037336274
-
Crystal structure of the E. coli Hsp100 ClpB N-terminal domain
-
Li, J.; Sha, B. Crystal structure of the E. coli Hsp100 ClpB N-terminal domain. Structure (Camb), 2003, 11, 323-328.
-
(2003)
Structure (Camb)
, vol.11
, pp. 323-328
-
-
Li, J.1
Sha, B.2
-
120
-
-
8844251486
-
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB
-
Weibezahn, J.; Tessarz, P.; Schlieker, C.; Zahn, R.; Maglica, Z.; Lee, S.; Zentgraf, H.; Weber-Ban, E.U.; Dougan, D.A.; Tsai, F.T.; Mogk, A.; Bukau, B. Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell, 2004, 119, 653-665.
-
(2004)
Cell
, vol.119
, pp. 653-665
-
-
Weibezahn, J.1
Tessarz, P.2
Schlieker, C.3
Zahn, R.4
Maglica, Z.5
Lee, S.6
Zentgraf, H.7
Weber-Ban, E.U.8
Dougan, D.A.9
Tsai, F.T.10
Mogk, A.11
Bukau, B.12
-
121
-
-
0035783169
-
Mechanisms of chaperone-mediated protein disaggregation
-
Ben-Zvi, A.; Goloubinoff, P. Mechanisms of chaperone-mediated protein disaggregation. J. Struct. Biol., 2001, 135, 84-93.
-
(2001)
J. Struct. Biol
, vol.135
, pp. 84-93
-
-
Ben-Zvi, A.1
Goloubinoff, P.2
-
122
-
-
10044275315
-
Solubilization of aggregated proteins by ClpB/DnaK relies on the continuous extraction of unfolded polypeptides
-
Schlieker, C.; Tews, I.; Bukau, B.; Mogk, A. Solubilization of aggregated proteins by ClpB/DnaK relies on the continuous extraction of unfolded polypeptides. FEBS Lett., 2004, 578, 351-356.
-
(2004)
FEBS Lett
, vol.578
, pp. 351-356
-
-
Schlieker, C.1
Tews, I.2
Bukau, B.3
Mogk, A.4
-
123
-
-
38549119467
-
Chaperones in control of protein disaggregation
-
Liberek, K.; Lewandowska, A.; Zietkiewicz, S. Chaperones in control of protein disaggregation. EMBO J., 2008, 27, 328-335.
-
(2008)
EMBO J
, vol.27
, pp. 328-335
-
-
Liberek, K.1
Lewandowska, A.2
Zietkiewicz, S.3
-
124
-
-
33846941900
-
Asymmetric deceleration of ClpB and Hsp104 ATPase activity unleashes protein-remodeling activity
-
Doyle, S.M.; Shorter, J.; Zolkiewski, M.; Hoskins, J.R.; Lindquist, S.; Wickner, S. Asymmetric deceleration of ClpB and Hsp104 ATPase activity unleashes protein-remodeling activity. Nat. Struct. Mol. Biol., 2007, 14, 114-122.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 114-122
-
-
Doyle, S.M.1
Shorter, J.2
Zolkiewski, M.3
Hoskins, J.R.4
Lindquist, S.5
Wickner, S.6
-
125
-
-
54349091742
-
Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions
-
Shorter, J.; Lindquist, S. Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions. EMBO J., 2008, 27, 2712-2724.
-
(2008)
EMBO J
, vol.27
, pp. 2712-2724
-
-
Shorter, J.1
Lindquist, S.2
-
126
-
-
26844539619
-
Novel insights into the mechanism of chaperone-assisted protein disaggregation
-
Weibezahn, J.; Schlieker, C.; Tessarz, P.; Mogk, A.; Bukau B. Novel insights into the mechanism of chaperone-assisted protein disaggregation. Biol. Chem., 2005, 386, 739-744.
-
(2005)
Biol. Chem
, vol.386
, pp. 739-744
-
-
Weibezahn, J.1
Schlieker, C.2
Tessarz, P.3
Mogk, A.4
Bukau, B.5
-
127
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
Rutherford, S.L.; Lindquist, S. Hsp90 as a capacitor for morphological evolution. Nature, 1998, 396, 336-342.
-
(1998)
Nature
, vol.396
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
128
-
-
36949033246
-
Two families of chaperonin: Physiology and mechanism
-
Horwich, A.L.; Fenton, W.A.; Chapman, E.; Farr, G.W. Two families of chaperonin: Physiology and mechanism. Annu. Rev. Cell. Dev. Biol., 2007, 23, 115-145.
-
(2007)
Annu. Rev. Cell. Dev. Biol
, vol.23
, pp. 115-145
-
-
Horwich, A.L.1
Fenton, W.A.2
Chapman, E.3
Farr, G.W.4
-
129
-
-
0035715944
-
Allostery and protein substrate conformational change during GroEL/GroES-mediated protein folding
-
Saibil, H.R.; Horwich, A.L.; Fenton, W.A. Allostery and protein substrate conformational change during GroEL/GroES-mediated protein folding. Adv. Protein. Chem., 2001, 59, 45-72.
-
(2001)
Adv. Protein. Chem
, vol.59
, pp. 45-72
-
-
Saibil, H.R.1
Horwich, A.L.2
Fenton, W.A.3
-
130
-
-
0029583647
-
The protein-folding activity of chaperonins correlates with the symmetric GroEL-14(GroES-7)-2 heterooligomer
-
Azem, A.; Diamant, S.; Kessel, M.; Weiss, C.; Goloubinoff, P. The protein-folding activity of chaperonins correlates with the symmetric GroEL-14(GroES-7)-2 heterooligomer. Proc. Natl. Acad. Sci. USA, 1995, 92, 12021-12025.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12021-12025
-
-
Azem, A.1
Diamant, S.2
Kessel, M.3
Weiss, C.4
Goloubinoff, P.5
-
131
-
-
0030018794
-
Fluorescence detection of symmetric GroEL14(GroES7)2 hetero-oligomers involved in protein-release during the chaperonin cycle
-
Török, Z.; Vigh, L.; Goloubinoff, P. Fluorescence detection of symmetric GroEL14(GroES7)2 hetero-oligomers involved in protein-release during the chaperonin cycle. J. Biol. Chem., 1996, 271, 16180-16186.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 16180-16186
-
-
Török, Z.1
Vigh, L.2
Goloubinoff, P.3
-
132
-
-
53049103895
-
Revisiting the GroEL-GroES reaction cycle via the symmetrical intermediate implied by novel aspects of the GroEL (D398A) mutant
-
Koike-Takeshita, A.; Yoshida, M.; Taguchi, H. Revisiting the GroEL-GroES reaction cycle via the symmetrical intermediate implied by novel aspects of the GroEL (D398A) mutant. J. Biol. Chem., 2008, 283, 23774-23781.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 23774-23781
-
-
Koike-Takeshita, A.1
Yoshida, M.2
Taguchi, H.3
-
133
-
-
53049090990
-
Football- and bullet-shaped GroEL-GroES complexes coexist during the reaction cycle
-
Sameshima, T.; Ueno, T.; Iizuka, R.; Ishii, N.; Terada, N.; Okabe, K.; Funatsu, T. Football- and bullet-shaped GroEL-GroES complexes coexist during the reaction cycle. J. Biol. Chem., 2008, 283, 23765-23773.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 23765-23773
-
-
Sameshima, T.1
Ueno, T.2
Iizuka, R.3
Ishii, N.4
Terada, N.5
Okabe, K.6
Funatsu, T.7
-
134
-
-
33746099650
-
Protein aggregation in crowded environments
-
Ellis, R.J.; Minton, A.P. Protein aggregation in crowded environments. Biol. Chem., 2006, 387, 485-497.
-
(2006)
Biol. Chem
, vol.387
, pp. 485-497
-
-
Ellis, R.J.1
Minton, A.P.2
-
135
-
-
0033617534
-
Chaperonin function: Folding by forced unfolding
-
Shtilerman, M.; Lorimer, G.H.; Englander, S.W. Chaperonin function: folding by forced unfolding. Science, 1999, 284, 822-825.
-
(1999)
Science
, vol.284
, pp. 822-825
-
-
Shtilerman, M.1
Lorimer, G.H.2
Englander, S.W.3
-
136
-
-
56249135270
-
Chaperonin chamber accelerates protein folding through passive action of preventing aggregation
-
Apetri, A.C.; Horwich, A.L. Chaperonin chamber accelerates protein folding through passive action of preventing aggregation. Proc. Natl. Acad. Sci. USA, 2008, 105, 17351-17355.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 17351-17355
-
-
Apetri, A.C.1
Horwich, A.L.2
-
137
-
-
33646897305
-
Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein
-
Tang, Y.C.; Chang, H.C.; Roeben, A.; Wischnewski, D.; Wischnewski, N.; Kerner, M.J.; Hartl, F.U.; Hayer-Hartl, M. Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein. Cell, 2006, 125, 903-914.
-
(2006)
Cell
, vol.125
, pp. 903-914
-
-
Tang, Y.C.1
Chang, H.C.2
Roeben, A.3
Wischnewski, D.4
Wischnewski, N.5
Kerner, M.J.6
Hartl, F.U.7
Hayer-Hartl, M.8
-
138
-
-
41149089882
-
Monitoring protein conformation along the pathway of chaperonin-assisted folding
-
Sharma, S.; Chakraborty, K.; Müller, B.K.; Astola, N.; Tang, Y.C.; Lamb, D.C.; Hayer-Hartl, M.; Hartl, F.U. Monitoring protein conformation along the pathway of chaperonin-assisted folding. Cell, 2008, 133, 142-153.
-
(2008)
Cell
, vol.133
, pp. 142-153
-
-
Sharma, S.1
Chakraborty, K.2
Müller, B.K.3
Astola, N.4
Tang, Y.C.5
Lamb, D.C.6
Hayer-Hartl, M.7
Hartl, F.U.8
-
139
-
-
40949124274
-
GroEL stimulates protein folding through forced unfolding
-
Lin, Z.; Madan, D.; Rye, H.S. GroEL stimulates protein folding through forced unfolding. Nat. Struct. Mol. Biol., 2008, 15, 303-311.
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 303-311
-
-
Lin, Z.1
Madan, D.2
Rye, H.S.3
-
140
-
-
61649098007
-
Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket
-
Donnelly, A.; Blagg, B.S. Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. Curr. Med. Chem., 2008, 15, 2702-2717.
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 2702-2717
-
-
Donnelly, A.1
Blagg, B.S.2
-
141
-
-
33750033278
-
The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase
-
Gadelle, D.; Graille, M.; Forterre, P. The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase. Biochem. Pharmacol., 2006, 72, 1207-1216.
-
(2006)
Biochem. Pharmacol
, vol.72
, pp. 1207-1216
-
-
Gadelle, D.1
Graille, M.2
Forterre, P.3
-
142
-
-
0026778032
-
Hsp90 chaperones-protein folding in vitro
-
Wiech, H.; Buchner, J.; Zimmermann, R.; Jakob, U. Hsp90 chaperones-protein folding in vitro. Nature, 1992, 358, 169-170.
-
(1992)
Nature
, vol.358
, pp. 169-170
-
-
Wiech, H.1
Buchner, J.2
Zimmermann, R.3
Jakob, U.4
-
143
-
-
49649117517
-
The Hsp90 chaperone machinery
-
Wandinger, S.K.; Richter, K.; Buchner, J. The Hsp90 chaperone machinery. J. Biol. Chem., 2008, 283, 18473-18477.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 18473-18477
-
-
Wandinger, S.K.1
Richter, K.2
Buchner, J.3
-
144
-
-
0027291238
-
Heat shock protein hsp90 governs the activity of pp60v-src kinase
-
Xu, Y.; Lindquist, S. Heat shock protein hsp90 governs the activity of pp60v-src kinase. Proc. Natl. Acad. Sci. USA, 1993, 90, 7074-7078.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7074-7078
-
-
Xu, Y.1
Lindquist, S.2
-
145
-
-
33750008686
-
Structural analysis of E. coli hsp90 reveals dramatic nucleotidedependent conformational rearrangements
-
Shiau, A.K.; Harris, S.F.; Southworth, D.R.; Agard, D.A.; Structural analysis of E. coli hsp90 reveals dramatic nucleotidedependent conformational rearrangements. Cell, 2006, 127, 329-340.
-
(2006)
Cell
, vol.127
, pp. 329-340
-
-
Shiau, A.K.1
Harris, S.F.2
Southworth, D.R.3
Agard, D.A.4
-
146
-
-
50649116818
-
Misfolded proteins partition between two distinct quality control compartments
-
Kaganovich, D.; Kopito, R.; Frydman, J. Misfolded proteins partition between two distinct quality control compartments. Nature, 2008, 454, 1088-1095.
-
(2008)
Nature
, vol.454
, pp. 1088-1095
-
-
Kaganovich, D.1
Kopito, R.2
Frydman, J.3
-
147
-
-
56449083411
-
Autophagy in neurodegeneration and development
-
Winslow, A.R.; Rubinsztein, D.C. Autophagy in neurodegeneration and development. Biochim. Biophys. Acta., 2008, 1782, 723-729.
-
(2008)
Biochim. Biophys. Acta
, vol.1782
, pp. 723-729
-
-
Winslow, A.R.1
Rubinsztein, D.C.2
-
148
-
-
66649132872
-
Chaperonin overexpression promotes genetic variation and enzyme evolution
-
Touriki, N.; Tawfik, D.S. Chaperonin overexpression promotes genetic variation and enzyme evolution. Nature, 2009, 459, 668-673.
-
(2009)
Nature
, vol.459
, pp. 668-673
-
-
Touriki, N.1
Tawfik, D.S.2
|