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Angewandte Chemie - International Edition

Volumn 52, Issue 36, 2013, Pages 9442-9462

The chemistry and biology of soluble guanylate cyclase stimulators and activators

(11) Follmann, Markus a Griebenow, Nils a Hahn, Michael G a Hartung, Ingo a Mais, Franz Josef a Mittendorf, Joachim a Schäfer, Martina a Schirok, Hartmut a Stasch, Johannes Peter a Stoll, Friederike a Straub, Alexander a

a BAYER PHARMA AG (Germany)

Author keywords

drug discovery; guanylate cyclase; medicinal chemistry; riociguat; structural biology

Indexed keywords

DRUG DISCOVERY; GUANYLATE CYCLASE; MEDICINAL CHEMISTRY; RIOCIGUAT; STRUCTURAL BIOLOGY;

CARDIOVASCULAR SYSTEM; NITRIC OXIDE; SIGNAL TRANSDUCTION;

DISEASE CONTROL;

CELL RECEPTOR; ENZYME ACTIVATOR; GUANYLATE CYCLASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIOCIGUAT; SOLUBLE GUANYLYL CYCLASE;

CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; MEDICINAL CHEMISTRY; METABOLISM; REVIEW; SIGNAL TRANSDUCTION; STRUCTURAL BIOLOGY;

DRUG DISCOVERY; GUANYLATE CYCLASE; MEDICINAL CHEMISTRY; RIOCIGUAT; STRUCTURAL BIOLOGY;

DRUG DISCOVERY; ENZYME ACTIVATION; ENZYME ACTIVATORS; GUANYLATE CYCLASE; HUMANS; PYRAZOLES; PYRIMIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION;

EID: 84883219083 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201302588 Document Type: Review

Times cited : (175)

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