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Volumn 10, Issue 6, 2002, Pages 1711-1717
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Metabolites of orally active NO-independent pyrazolopyridine stimulators of soluble guanylate cyclase
a,c
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Author keywords
[No Author keywords available]
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Indexed keywords
2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL] 5 MORPHOLINO 4,6 PYRIMIDINEDIAMINE;
4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE;
CYCLOPROPANE DERIVATIVE;
DRUG METABOLITE;
GUANYLATE CYCLASE;
PYRAZOLOPYRIMIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
3 (4 AMINO 5 CYCLOPROPYLPYRIMIDINE 2 YL) 1 (2 FLUOROBENZYL) 1H PYRAZOLO(3,4 B)PYRIDINE;
3-(4-AMINO-5-CYCLOPROPYLPYRIMIDINE-2-YL)-1-(2-FLUOROBENZYL)-1H-PYRAZOLO(3,4-B)PYRIDINE;
MORPHOLINE DERIVATIVE;
NITRIC OXIDE;
PYRAZOLE DERIVATIVE;
PYRAZOLOPYRIDINE;
PYRIDINE DERIVATIVE;
PYRIMIDINE DERIVATIVE;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DOG;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG SYNTHESIS;
IN VIVO STUDY;
MALE;
NONHUMAN;
RAT;
VASODILATATION;
ANIMAL;
AORTA;
BLOOD;
BLOOD PRESSURE;
CHEMICAL STRUCTURE;
CHEMISTRY;
DRUG EFFECT;
ENZYME ACTIVATION;
ENZYMOLOGY;
IN VITRO STUDY;
INTRAVENOUS DRUG ADMINISTRATION;
LUNG;
METABOLISM;
ORAL DRUG ADMINISTRATION;
SOLUBILITY;
WISTAR RAT;
X RAY CRYSTALLOGRAPHY;
CANIS FAMILIARIS;
ADMINISTRATION, ORAL;
ANIMALS;
AORTA;
BLOOD PRESSURE;
CRYSTALLOGRAPHY, X-RAY;
DOGS;
ENZYME ACTIVATION;
GUANYLATE CYCLASE;
INJECTIONS, INTRAVENOUS;
LUNG;
MOLECULAR STRUCTURE;
MORPHOLINES;
NITRIC OXIDE;
PYRAZOLES;
PYRIDINES;
PYRIMIDINES;
RATS;
RATS, WISTAR;
SOLUBILITY;
VASODILATION;
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EID: 0036009870
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(02)00034-2 Document Type: Article |
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Times cited : (69)
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References (39)
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