Soluble guanylate cyclase is activated differently by excess no and by yc-1: Resonance raman spectroscopic evidence

Biochemistry

Volumn 49, Issue 23, 2010, Pages 4864-4871

  Ibrahim, Mohammed ^a   Derbyshire, Emily R ^b,c   Soldatova, Alexandra V ^a   Marletta, Michael A ^b   Spiro, Thomas G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC ACTIVATOR; DFT CALCULATION; DIFFERENT MECHANISMS; ELECTRONIC ABSORPTION; GUANYLATE CYCLASE; HEME COFACTOR; PYRROLE RING; RESONANCE RAMAN; SOLUBLE GUANYLATE CYCLASE (SGC); SPECTRAL DIFFERENCES; SPECTROSCOPIC METHOD; STOICHIOMETRIC BINDING; STRETCHING FREQUENCY;

CHEMICAL ACTIVATION; HEMOGLOBIN; NITRIC OXIDE; PORPHYRINS; RAMAN SPECTROSCOPY; RESONANCE; SPECTROSCOPIC ANALYSIS;

ABSORPTION SPECTROSCOPY;

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; GUANYLATE CYCLASE; HEME; NITRIC OXIDE;

ARTICLE; BINDING SITE; COMPARATIVE STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; PRIORITY JOURNAL; PROTEIN STRUCTURE, FUNCTION AND VARIABILITY; RAMAN SPECTROMETRY; SOLUBILITY; STOICHIOMETRY;

ALLOSTERIC REGULATION; ANIMALS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATORS; GUANYLATE CYCLASE; INDAZOLES; NITRIC OXIDE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS, RAMAN;

EID: 77953249645     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100506j     Document Type: Article

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