A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway

Analytical Biochemistry

Volumn 339, Issue 1, 2005, Pages 104-112

  Wunder, Frank ^a   Stasch, Johannes Peter ^a   Hütter, Joachim ^a   Alonso Alija, Cristina ^a   Hüser, Jörg ^a   Lohrmann, Emanuel ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

BAY 41 2272; BAY 58 2667; cGMP; CNG channel; HTS; Nitric oxide; Soluble guanylate cyclase

Indexed keywords

CELL CULTURE; NITRIC OXIDE; NUCLEOTIDES;

BAY 41-2272; BAY 58-2667; CGMP; CNG CHANNEL; GUANYLATE CYCLASE;

CELLS;

4 [[4 CARBOXYBUTYL [2 [(4 PHENETHYLBENZYL)OXY]PHENETHYL]AMINO]METHYL] BENZOIC ACID; 4 [[4 CARBOXYBUTYL[2 [(4 PHENETHYLBENZYL)OXY]PHENETHYL]AMINO]METHYL]BENZOIC ACID; AEQUORIN; AMINO ACID DERIVATIVE; CYCLIC GMP; DICARBOXYLIC ACID DERIVATIVE; GUANYLATE CYCLASE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOMATION; BIOASSAY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; LUMINESCENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCREENING TEST;

CRICETINAE; CRICETULUS GRISEUS;

EID: 14844312091     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.12.025     Document Type: Article

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