메뉴 건너뛰기




Volumn 31, Issue 6, 2013, Pages 976-985

Combinatorial genetic perturbation to refine metabolic circuits for producing biofuels and biochemicals

Author keywords

Biochemical; Biofuel; Combinatorial library; Inverse metabolic engineering; Metabolic circuit

Indexed keywords

BIOCHEMICAL; BIOFUELS AND BIOCHEMICALS; COMBINATORIAL APPROACH; COMBINATORIAL LIBRARY; EFFECTIVE TOOL; HIGH-THROUGHPUT SCREENING; INVERSE METABOLIC ENGINEERING; STRAIN IMPROVEMENT;

EID: 84882637876     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2013.03.010     Document Type: Review
Times cited : (22)

References (98)
  • 1
    • 77957329119 scopus 로고    scopus 로고
    • Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli
    • Ajikumar P.K., Xiao W.H., Tyo K.E., Wang Y., Simeon F., Leonard E., et al. Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. Science 2010, 330:70-74.
    • (2010) Science , vol.330 , pp. 70-74
    • Ajikumar, P.K.1    Xiao, W.H.2    Tyo, K.E.3    Wang, Y.4    Simeon, F.5    Leonard, E.6
  • 2
    • 33847083318 scopus 로고    scopus 로고
    • Global transcription machinery engineering: a new approach for improving cellular phenotype
    • Alper H., Stephanopoulos G. Global transcription machinery engineering: a new approach for improving cellular phenotype. Metab Eng 2007, 9:258-267.
    • (2007) Metab Eng , vol.9 , pp. 258-267
    • Alper, H.1    Stephanopoulos, G.2
  • 3
    • 41049115923 scopus 로고    scopus 로고
    • Uncovering the gene knockout landscape for improved lycopene production in E. coli
    • Alper H., Stephanopoulos G. Uncovering the gene knockout landscape for improved lycopene production in E. coli. Appl Microbiol Biotechnol 2008, 78:801-810.
    • (2008) Appl Microbiol Biotechnol , vol.78 , pp. 801-810
    • Alper, H.1    Stephanopoulos, G.2
  • 4
    • 70349281876 scopus 로고    scopus 로고
    • Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?
    • Alper H., Stephanopoulos G. Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?. Nat Rev Microbiol 2009, 7:715-723.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 715-723
    • Alper, H.1    Stephanopoulos, G.2
  • 6
    • 18844392599 scopus 로고    scopus 로고
    • Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli
    • Alper H., Jin Y.S., Moxley J.F., Stephanopoulos G. Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 2005, 7:155-164.
    • (2005) Metab Eng , vol.7 , pp. 155-164
    • Alper, H.1    Jin, Y.S.2    Moxley, J.F.3    Stephanopoulos, G.4
  • 7
    • 22844452835 scopus 로고    scopus 로고
    • Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets
    • Alper H., Miyaoku K., Stephanopoulos G. Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets. Nat Biotechnol 2005, 23:612-616.
    • (2005) Nat Biotechnol , vol.23 , pp. 612-616
    • Alper, H.1    Miyaoku, K.2    Stephanopoulos, G.3
  • 8
    • 33845442201 scopus 로고    scopus 로고
    • Engineering yeast transcription machinery for improved ethanol tolerance and production
    • Alper H., Moxley J., Nevoigt E., Fink G.R., Stephanopoulos G. Engineering yeast transcription machinery for improved ethanol tolerance and production. Science 2006, 314:1565-1568.
    • (2006) Science , vol.314 , pp. 1565-1568
    • Alper, H.1    Moxley, J.2    Nevoigt, E.3    Fink, G.R.4    Stephanopoulos, G.5
  • 9
    • 33747173376 scopus 로고    scopus 로고
    • Mutagenesis strategies in zebrafish for identifying genes involved in development and disease
    • Amsterdam A., Hopkins N. Mutagenesis strategies in zebrafish for identifying genes involved in development and disease. Trends Genet 2006, 22:473-478.
    • (2006) Trends Genet , vol.22 , pp. 473-478
    • Amsterdam, A.1    Hopkins, N.2
  • 10
    • 0036898867 scopus 로고    scopus 로고
    • Modular design of artificial transcription factors
    • Ansari A.Z., Mapp A.K. Modular design of artificial transcription factors. Curr Opin Chem Biol 2002, 6:765-772.
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 765-772
    • Ansari, A.Z.1    Mapp, A.K.2
  • 11
    • 79952348850 scopus 로고    scopus 로고
    • A synthetic library of RNA control modules for predictable tuning of gene expression in yeast
    • Babiskin A.H., Smolke C.D. A synthetic library of RNA control modules for predictable tuning of gene expression in yeast. Mol Syst Biol 2011, 7:471.
    • (2011) Mol Syst Biol , vol.7 , pp. 471
    • Babiskin, A.H.1    Smolke, C.D.2
  • 12
  • 13
    • 79955164750 scopus 로고    scopus 로고
    • Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli
    • Bastian S., Liu X., Meyerowitz J.T., Snow C.D., Chen M.M., Arnold F.H. Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli. Metab Eng 2011, 13:345-352.
    • (2011) Metab Eng , vol.13 , pp. 345-352
    • Bastian, S.1    Liu, X.2    Meyerowitz, J.T.3    Snow, C.D.4    Chen, M.M.5    Arnold, F.H.6
  • 14
    • 77954699474 scopus 로고    scopus 로고
    • Systems metabolic engineering: genome-scale models and beyond
    • Blazeck J., Alper H. Systems metabolic engineering: genome-scale models and beyond. Biotechnol J 2010, 5:647-659.
    • (2010) Biotechnol J , vol.5 , pp. 647-659
    • Blazeck, J.1    Alper, H.2
  • 15
    • 83055177124 scopus 로고    scopus 로고
    • Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach
    • Blazeck J., Liu L., Redden H., Alper H. Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach. Appl Environ Microbiol 2011, 77:7905-7914.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 7905-7914
    • Blazeck, J.1    Liu, L.2    Redden, H.3    Alper, H.4
  • 16
    • 33750982685 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis of glycan libraries
    • Blixt O., Razi N. Chemoenzymatic synthesis of glycan libraries. Methods Enzymol 2006, 415:137-153.
    • (2006) Methods Enzymol , vol.415 , pp. 137-153
    • Blixt, O.1    Razi, N.2
  • 17
    • 34248196414 scopus 로고    scopus 로고
    • Dynamics of genomic-library enrichment and identification of solvent tolerance genes for Clostridium acetobutylicum
    • Borden J.R., Papoutsakis E.T. Dynamics of genomic-library enrichment and identification of solvent tolerance genes for Clostridium acetobutylicum. Appl Environ Microbiol 2007, 73:3061-3068.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 3061-3068
    • Borden, J.R.1    Papoutsakis, E.T.2
  • 18
    • 77950857795 scopus 로고    scopus 로고
    • A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing
    • Borden J.R., Jones S.W., Indurthi D., Chen Y., Papoutsakis E.T. A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing. Metab Eng 2010, 12:268-281.
    • (2010) Metab Eng , vol.12 , pp. 268-281
    • Borden, J.R.1    Jones, S.W.2    Indurthi, D.3    Chen, Y.4    Papoutsakis, E.T.5
  • 19
    • 77949873378 scopus 로고    scopus 로고
    • Review: continuous hydrolysis and fermentation for cellulosic ethanol production
    • Brethauer S., Wyman C.E. Review: continuous hydrolysis and fermentation for cellulosic ethanol production. Bioresour Technol 2010, 101:4862-4874.
    • (2010) Bioresour Technol , vol.101 , pp. 4862-4874
    • Brethauer, S.1    Wyman, C.E.2
  • 20
    • 3242726864 scopus 로고    scopus 로고
    • Impact of 'ome' analyses on inverse metabolic engineering
    • Bro C., Nielsen J. Impact of 'ome' analyses on inverse metabolic engineering. Metab Eng 2004, 6:204-211.
    • (2004) Metab Eng , vol.6 , pp. 204-211
    • Bro, C.1    Nielsen, J.2
  • 21
    • 0037329757 scopus 로고    scopus 로고
    • Mutagenesis strategies for identifying novel loci associated with disease phenotypes
    • Brown S.D., Hardisty R.E. Mutagenesis strategies for identifying novel loci associated with disease phenotypes. Semin Cell Dev Biol 2003, 14:19-24.
    • (2003) Semin Cell Dev Biol , vol.14 , pp. 19-24
    • Brown, S.D.1    Hardisty, R.E.2
  • 22
    • 84857056878 scopus 로고    scopus 로고
    • Evolutionary engineering of Saccharomyces cerevisiae for improved industrially important properties
    • Cakar Z.P., Turanli-Yildiz B., Alkim C., Yilmaz U. Evolutionary engineering of Saccharomyces cerevisiae for improved industrially important properties. FEMS Yeast Res 2012, 12:171-182.
    • (2012) FEMS Yeast Res , vol.12 , pp. 171-182
    • Cakar, Z.P.1    Turanli-Yildiz, B.2    Alkim, C.3    Yilmaz, U.4
  • 23
    • 77249149861 scopus 로고    scopus 로고
    • Biofuel production in Escherichia coli: the role of metabolic engineering and synthetic biology
    • Clomburg J.M., Gonzalez R. Biofuel production in Escherichia coli: the role of metabolic engineering and synthetic biology. Appl Microbiol Biotechnol 2010, 86:419-434.
    • (2010) Appl Microbiol Biotechnol , vol.86 , pp. 419-434
    • Clomburg, J.M.1    Gonzalez, R.2
  • 24
    • 84855161202 scopus 로고    scopus 로고
    • The role of synthetic biology in the design of microbial cell factories for biofuel production
    • Colin V.L., Rodriguez A., Cristobal H.A. The role of synthetic biology in the design of microbial cell factories for biofuel production. J Biomed Biotechnol 2011, 2011:601834.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 601834
    • Colin, V.L.1    Rodriguez, A.2    Cristobal, H.A.3
  • 25
    • 79960104605 scopus 로고    scopus 로고
    • Microbial laboratory evolution in the era of genome-scale science
    • Conrad T.M., Lewis N.E., Palsson B.O. Microbial laboratory evolution in the era of genome-scale science. Mol Syst Biol 2011, 7:509.
    • (2011) Mol Syst Biol , vol.7 , pp. 509
    • Conrad, T.M.1    Lewis, N.E.2    Palsson, B.O.3
  • 26
    • 0035103447 scopus 로고    scopus 로고
    • An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
    • De Backer M.D., Nelissen B., Logghe M., Viaene J., Loonen I., Vandoninck S., et al. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans. Nat Biotechnol 2001, 19:235-241.
    • (2001) Nat Biotechnol , vol.19 , pp. 235-241
    • De Backer, M.D.1    Nelissen, B.2    Logghe, M.3    Viaene, J.4    Loonen, I.5    Vandoninck, S.6
  • 27
    • 28444467392 scopus 로고    scopus 로고
    • Quantitative trait loci mapped to single-nucleotide resolution in yeast
    • Deutschbauer A.M., Davis R.W. Quantitative trait loci mapped to single-nucleotide resolution in yeast. Nat Genet 2005, 37:1333-1340.
    • (2005) Nat Genet , vol.37 , pp. 1333-1340
    • Deutschbauer, A.M.1    Davis, R.W.2
  • 29
    • 84865278051 scopus 로고    scopus 로고
    • Customized optimization of metabolic pathways by combinatorial transcriptional engineering
    • Du J., Yuan Y., Si T., Lian J., Zhao H. Customized optimization of metabolic pathways by combinatorial transcriptional engineering. Nucleic Acids Res 2012, 40:e142.
    • (2012) Nucleic Acids Res , vol.40
    • Du, J.1    Yuan, Y.2    Si, T.3    Lian, J.4    Zhao, H.5
  • 31
    • 80053293747 scopus 로고    scopus 로고
    • Applications of systems biology towards microbial fuel production
    • Gowen C.M., Fong S.S. Applications of systems biology towards microbial fuel production. Trends Microbiol 2011, 19:516-524.
    • (2011) Trends Microbiol , vol.19 , pp. 516-524
    • Gowen, C.M.1    Fong, S.S.2
  • 32
    • 70349665214 scopus 로고    scopus 로고
    • Life without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae
    • Harrison B.R., Yazgan O., Krebs J.E. Life without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae. Biochem Cell Biol 2009, 87:767-779.
    • (2009) Biochem Cell Biol , vol.87 , pp. 767-779
    • Harrison, B.R.1    Yazgan, O.2    Krebs, J.E.3
  • 34
    • 84864186953 scopus 로고    scopus 로고
    • Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries
    • Hong K.K., Nielsen J. Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries. Cell Mol Life Sci 2012, 69:2671-2690.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2671-2690
    • Hong, K.K.1    Nielsen, J.2
  • 35
    • 77955430660 scopus 로고    scopus 로고
    • Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering
    • Hong M.E., Lee K.S., Yu B.J., Sung Y.J., Park S.M., Koo H.M., et al. Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. J Biotechnol 2010, 149:52-59.
    • (2010) J Biotechnol , vol.149 , pp. 52-59
    • Hong, M.E.1    Lee, K.S.2    Yu, B.J.3    Sung, Y.J.4    Park, S.M.5    Koo, H.M.6
  • 36
    • 79961072482 scopus 로고    scopus 로고
    • Unravelling evolutionary strategies of yeast for improving galactose utilization through integrated systems level analysis
    • Hong K.K., Vongsangnak W., Vemuri G.N., Nielsen J. Unravelling evolutionary strategies of yeast for improving galactose utilization through integrated systems level analysis. Proc Natl Acad Sci U S A 2011, 108:12179-12184.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12179-12184
    • Hong, K.K.1    Vongsangnak, W.2    Vemuri, G.N.3    Nielsen, J.4
  • 37
    • 79960502359 scopus 로고    scopus 로고
    • Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
    • Isaacs F.J., Carr P.A., Wang H.H., Lajoie M.J., Sterling B., Kraal L., et al. Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science 2011, 333:348-353.
    • (2011) Science , vol.333 , pp. 348-353
    • Isaacs, F.J.1    Carr, P.A.2    Wang, H.H.3    Lajoie, M.J.4    Sterling, B.5    Kraal, L.6
  • 38
    • 0032485843 scopus 로고    scopus 로고
    • Artificial promoters for metabolic optimization
    • Jensen P.R., Hammer K. Artificial promoters for metabolic optimization. Biotechnol Bioeng 1998, 58:191-195.
    • (1998) Biotechnol Bioeng , vol.58 , pp. 191-195
    • Jensen, P.R.1    Hammer, K.2
  • 39
    • 0031965086 scopus 로고    scopus 로고
    • The sequence of spacers between the consensus sequences modulates the strength of prokaryotic promoters
    • Jensen P.R., Hammer K. The sequence of spacers between the consensus sequences modulates the strength of prokaryotic promoters. Appl Environ Microbiol 1998, 64:82-87.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 82-87
    • Jensen, P.R.1    Hammer, K.2
  • 40
    • 34547109364 scopus 로고    scopus 로고
    • Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli
    • Jin Y.S., Stephanopoulos G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng 2007, 9:337-347.
    • (2007) Metab Eng , vol.9 , pp. 337-347
    • Jin, Y.S.1    Stephanopoulos, G.2
  • 41
    • 29144502422 scopus 로고    scopus 로고
    • Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach
    • Jin Y.S., Alper H., Yang Y.T., Stephanopoulos G. Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Appl Environ Microbiol 2005, 71:8249-8256.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 8249-8256
    • Jin, Y.S.1    Alper, H.2    Yang, Y.T.3    Stephanopoulos, G.4
  • 42
    • 40149109321 scopus 로고    scopus 로고
    • A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae
    • Jones G.M., Stalker J., Humphray S., West A., Cox T., Rogers J., et al. A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae. Nat Methods 2008, 5:239-241.
    • (2008) Nat Methods , vol.5 , pp. 239-241
    • Jones, G.M.1    Stalker, J.2    Humphray, S.3    West, A.4    Cox, T.5    Rogers, J.6
  • 43
    • 84857058761 scopus 로고    scopus 로고
    • A systems-level approach for metabolic engineering of yeast cell factories
    • Kim I.K., Roldao A., Siewers V., Nielsen J. A systems-level approach for metabolic engineering of yeast cell factories. FEMS Yeast Res 2012, 12:228-248.
    • (2012) FEMS Yeast Res , vol.12 , pp. 228-248
    • Kim, I.K.1    Roldao, A.2    Siewers, V.3    Nielsen, J.4
  • 44
    • 84862231336 scopus 로고    scopus 로고
    • High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae
    • Kim S.R., Ha S.J., Kong I.I., Jin Y.S. High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae. Metab Eng 2012, 14:336-343.
    • (2012) Metab Eng , vol.14 , pp. 336-343
    • Kim, S.R.1    Ha, S.J.2    Kong, I.I.3    Jin, Y.S.4
  • 46
    • 29244486764 scopus 로고    scopus 로고
    • Artificial transcription factors increase production of recombinant antibodies in Chinese hamster ovary cells
    • Kwon R.J., Kim S.K., Lee S.I., Hwang S.J., Lee G.M., Kim J.S., et al. Artificial transcription factors increase production of recombinant antibodies in Chinese hamster ovary cells. Biotechnol Lett 2006, 28:9-15.
    • (2006) Biotechnol Lett , vol.28 , pp. 9-15
    • Kwon, R.J.1    Kim, S.K.2    Lee, S.I.3    Hwang, S.J.4    Lee, G.M.5    Kim, J.S.6
  • 47
    • 77956017180 scopus 로고    scopus 로고
    • Enhancing stress resistance and production phenotypes through transcriptome engineering
    • Lam F.H., Hartner F.S., Fink G.R., Stephanopoulos G. Enhancing stress resistance and production phenotypes through transcriptome engineering. Methods Enzymol 2010, 470:509-532.
    • (2010) Methods Enzymol , vol.470 , pp. 509-532
    • Lam, F.H.1    Hartner, F.S.2    Fink, G.R.3    Stephanopoulos, G.4
  • 48
    • 70349482673 scopus 로고    scopus 로고
    • Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing
    • Le Crom S., Schackwitz W., Pennacchio L., Magnuson J.K., Culley D.E., Collett J.R., et al. Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing. Proc Natl Acad Sci U S A 2009, 106:16151-16156.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16151-16156
    • Le Crom, S.1    Schackwitz, W.2    Pennacchio, L.3    Magnuson, J.K.4    Culley, D.E.5    Collett, J.R.6
  • 49
    • 77954265373 scopus 로고    scopus 로고
    • Adaptive evolution of Escherichia coli K-12 MG1655 during growth on a nonnative carbon source, L-1,2-propanediol
    • Lee D.H., Palsson B.O. Adaptive evolution of Escherichia coli K-12 MG1655 during growth on a nonnative carbon source, L-1,2-propanediol. Appl Environ Microbiol 2010, 76:4158-4168.
    • (2010) Appl Environ Microbiol , vol.76 , pp. 4158-4168
    • Lee, D.H.1    Palsson, B.O.2
  • 50
    • 0346256837 scopus 로고    scopus 로고
    • Proteomic analysis of Candida magnoliae strains by two-dimensional gel electrophoresis and mass spectrometry
    • Lee D.Y., Park Y.C., Kim H.J., Ryu Y.W., Seo J.H. Proteomic analysis of Candida magnoliae strains by two-dimensional gel electrophoresis and mass spectrometry. Proteomics 2003, 3:2330-2338.
    • (2003) Proteomics , vol.3 , pp. 2330-2338
    • Lee, D.Y.1    Park, Y.C.2    Kim, H.J.3    Ryu, Y.W.4    Seo, J.H.5
  • 51
    • 52649115929 scopus 로고    scopus 로고
    • Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli
    • Lee J.Y., Sung B.H., Yu B.J., Lee J.H., Lee S.H., Kim M.S., et al. Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli. Nucleic Acids Res 2008, 36:e102.
    • (2008) Nucleic Acids Res , vol.36
    • Lee, J.Y.1    Sung, B.H.2    Yu, B.J.3    Lee, J.H.4    Lee, S.H.5    Kim, M.S.6
  • 52
    • 78751550488 scopus 로고    scopus 로고
    • Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering
    • Lee K.S., Hong M.E., Jung S.C., Ha S.J., Yu B.J., Koo H.M., et al. Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnol Bioeng 2011, 108:621-631.
    • (2011) Biotechnol Bioeng , vol.108 , pp. 621-631
    • Lee, K.S.1    Hong, M.E.2    Jung, S.C.3    Ha, S.J.4    Yu, B.J.5    Koo, H.M.6
  • 53
    • 84859480640 scopus 로고    scopus 로고
    • Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae
    • Lee S.H., Kodaki T., Park Y.C., Seo J.H. Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae. J Biotechnol 2012, 158:184-191.
    • (2012) J Biotechnol , vol.158 , pp. 184-191
    • Lee, S.H.1    Kodaki, T.2    Park, Y.C.3    Seo, J.H.4
  • 54
    • 78650155069 scopus 로고    scopus 로고
    • Biofuels: biomolecular engineering fundamentals and advances
    • Li H., Cann A.F., Liao J.C. Biofuels: biomolecular engineering fundamentals and advances. Annu Rev Chem Biomol Eng 2010, 1:19-36.
    • (2010) Annu Rev Chem Biomol Eng , vol.1 , pp. 19-36
    • Li, H.1    Cann, A.F.2    Liao, J.C.3
  • 55
    • 79954648688 scopus 로고    scopus 로고
    • Molecular mechanisms of yeast tolerance and in situ detoxification of lignocellulose hydrolysates
    • Liu Z.L. Molecular mechanisms of yeast tolerance and in situ detoxification of lignocellulose hydrolysates. Appl Microbiol Biotechnol 2011, 90:809-825.
    • (2011) Appl Microbiol Biotechnol , vol.90 , pp. 809-825
    • Liu, Z.L.1
  • 56
    • 33845948161 scopus 로고    scopus 로고
    • SCALEs: multiscale analysis of library enrichment
    • Lynch M.D., Warnecke T., Gill R.T. SCALEs: multiscale analysis of library enrichment. Nat Methods 2007, 4:87-93.
    • (2007) Nat Methods , vol.4 , pp. 87-93
    • Lynch, M.D.1    Warnecke, T.2    Gill, R.T.3
  • 57
    • 79955845844 scopus 로고    scopus 로고
    • Design and implementation of high throughput screening assays
    • Macarrón R., Hertzberg R.P. Design and implementation of high throughput screening assays. Mol Biotechnol 2011, 47:270-285.
    • (2011) Mol Biotechnol , vol.47 , pp. 270-285
    • Macarrón, R.1    Hertzberg, R.P.2
  • 58
    • 84865592819 scopus 로고    scopus 로고
    • A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols
    • Machado H.B., Dekishima Y., Luo H., Lan E.I., Liao J.C. A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols. Metab Eng 2012, 14:504-511.
    • (2012) Metab Eng , vol.14 , pp. 504-511
    • Machado, H.B.1    Dekishima, Y.2    Luo, H.3    Lan, E.I.4    Liao, J.C.5
  • 59
    • 79952806663 scopus 로고    scopus 로고
    • Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers
    • Madsen K.M., Udatha G.D., Semba S., Otero J.M., Koetter P., Nielsen J., et al. Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers. PLoS One 2011, 6:e14763.
    • (2011) PLoS One , vol.6
    • Madsen, K.M.1    Udatha, G.D.2    Semba, S.3    Otero, J.M.4    Koetter, P.5    Nielsen, J.6
  • 61
    • 84862167101 scopus 로고    scopus 로고
    • High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch
    • Michener J.K., Smolke C.D. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metab Eng 2012, 14:306-316.
    • (2012) Metab Eng , vol.14 , pp. 306-316
    • Michener, J.K.1    Smolke, C.D.2
  • 63
    • 0035666492 scopus 로고    scopus 로고
    • Transformation: a tool for studying fungal pathogens of plants
    • Mullins E.D., Kang S. Transformation: a tool for studying fungal pathogens of plants. Cell Mol Life Sci 2001, 58:2043-2052.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 2043-2052
    • Mullins, E.D.1    Kang, S.2
  • 64
    • 33747376106 scopus 로고    scopus 로고
    • Engineering of promoter replacement cassettes for fine-tuning of gene expression in Saccharomyces cerevisiae
    • Nevoigt E., Kohnke J., Fischer C.R., Alper H., Stahl U., Stephanopoulos G. Engineering of promoter replacement cassettes for fine-tuning of gene expression in Saccharomyces cerevisiae. Appl Environ Microbiol 2006, 72:5266-5273.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 5266-5273
    • Nevoigt, E.1    Kohnke, J.2    Fischer, C.R.3    Alper, H.4    Stahl, U.5    Stephanopoulos, G.6
  • 65
    • 10744225041 scopus 로고    scopus 로고
    • Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors
    • Park K.S., Lee D.K., Lee H., Lee Y., Jang Y.S., Kim Y.H., et al. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nat Biotechnol 2003, 21:1208-1214.
    • (2003) Nat Biotechnol , vol.21 , pp. 1208-1214
    • Park, K.S.1    Lee, D.K.2    Lee, H.3    Lee, Y.4    Jang, Y.S.5    Kim, Y.H.6
  • 66
    • 22544461606 scopus 로고    scopus 로고
    • Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells
    • Park K.S., Jang Y.S., Lee H., Kim J.S. Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells. J Bacteriol 2005, 187:5496-5499.
    • (2005) J Bacteriol , vol.187 , pp. 5496-5499
    • Park, K.S.1    Jang, Y.S.2    Lee, H.3    Kim, J.S.4
  • 67
    • 79955012346 scopus 로고    scopus 로고
    • Expression of aldehyde dehydrogenase 6 reduces inhibitory effect of furan derivatives on cell growth and ethanol production in Saccharomyces cerevisiae
    • Park S.E., Koo H.M., Park Y.K., Park S.M., Park J.C., Lee O.K., et al. Expression of aldehyde dehydrogenase 6 reduces inhibitory effect of furan derivatives on cell growth and ethanol production in Saccharomyces cerevisiae. Bioresour Technol 2011, 102:6033-6038.
    • (2011) Bioresour Technol , vol.102 , pp. 6033-6038
    • Park, S.E.1    Koo, H.M.2    Park, Y.K.3    Park, S.M.4    Park, J.C.5    Lee, O.K.6
  • 69
    • 34047179422 scopus 로고    scopus 로고
    • Genetic basis of individual differences in the response to small-molecule drugs in yeast
    • Perlstein E.O., Ruderfer D.M., Roberts D.C., Schreiber S.L., Kruglyak L. Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet 2007, 39:496-502.
    • (2007) Nat Genet , vol.39 , pp. 496-502
    • Perlstein, E.O.1    Ruderfer, D.M.2    Roberts, D.C.3    Schreiber, S.L.4    Kruglyak, L.5
  • 70
    • 33747078696 scopus 로고    scopus 로고
    • Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes
    • Pfleger B.F., Pitera D.J., Smolke C.D., Keasling J.D. Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat Biotechnol 2006, 24:1027-1032.
    • (2006) Nat Biotechnol , vol.24 , pp. 1027-1032
    • Pfleger, B.F.1    Pitera, D.J.2    Smolke, C.D.3    Keasling, J.D.4
  • 71
    • 79958264719 scopus 로고    scopus 로고
    • GAP promoter library for fine-tuning of gene expression in Pichia pastoris
    • Qin X., Qian J., Yao G., Zhuang Y., Zhang S., Chu J. GAP promoter library for fine-tuning of gene expression in Pichia pastoris. Appl Environ Microbiol 2011, 77:3600-3608.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 3600-3608
    • Qin, X.1    Qian, J.2    Yao, G.3    Zhuang, Y.4    Zhang, S.5    Chu, J.6
  • 72
    • 84855867175 scopus 로고    scopus 로고
    • Metabolic engineering of antibiotic-producing actinomycetes using in vitro transposon mutagenesis
    • Reeves A.R., Weber J.M. Metabolic engineering of antibiotic-producing actinomycetes using in vitro transposon mutagenesis. Methods Mol Biol 2012, 834:153-175.
    • (2012) Methods Mol Biol , vol.834 , pp. 153-175
    • Reeves, A.R.1    Weber, J.M.2
  • 73
    • 79952432805 scopus 로고    scopus 로고
    • Genomic library screens for genes involved in n-butanol tolerance in Escherichia coli
    • Reyes L.H., Almario M.P., Kao K.C. Genomic library screens for genes involved in n-butanol tolerance in Escherichia coli. PLoS One 2011, 6:e17678.
    • (2011) PLoS One , vol.6
    • Reyes, L.H.1    Almario, M.P.2    Kao, K.C.3
  • 74
    • 33645870422 scopus 로고    scopus 로고
    • Production of the antimalarial drug precursor artemisinic acid in engineered yeast
    • Ro D.K., Paradise E.M., Ouellet M., Fisher K.J., Newman K.L., Ndungu J.M., et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 2006, 440:940-943.
    • (2006) Nature , vol.440 , pp. 940-943
    • Ro, D.K.1    Paradise, E.M.2    Ouellet, M.3    Fisher, K.J.4    Newman, K.L.5    Ndungu, J.M.6
  • 75
    • 33645546618 scopus 로고    scopus 로고
    • A synthetic promoter library for constitutive gene expression in Lactobacillus plantarum
    • Rud I., Jensen P.R., Naterstad K., Axelsson L. A synthetic promoter library for constitutive gene expression in Lactobacillus plantarum. Microbiology 2006, 152:1011-1019.
    • (2006) Microbiology , vol.152 , pp. 1011-1019
    • Rud, I.1    Jensen, P.R.2    Naterstad, K.3    Axelsson, L.4
  • 76
    • 79952102774 scopus 로고    scopus 로고
    • Elucidating acetate tolerance in E. coli using a genome-wide approach
    • Sandoval N.R., Mills T.Y., Zhang M., Gill R.T. Elucidating acetate tolerance in E. coli using a genome-wide approach. Metab Eng 2011, 13:214-224.
    • (2011) Metab Eng , vol.13 , pp. 214-224
    • Sandoval, N.R.1    Mills, T.Y.2    Zhang, M.3    Gill, R.T.4
  • 77
    • 0035232377 scopus 로고    scopus 로고
    • Evolutionary engineering of industrially important microbial phenotypes
    • Sauer U. Evolutionary engineering of industrially important microbial phenotypes. Adv Biochem Eng Biotechnol 2001, 73:129-169.
    • (2001) Adv Biochem Eng Biotechnol , vol.73 , pp. 129-169
    • Sauer, U.1
  • 79
    • 0026780180 scopus 로고
    • Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters
    • Schultz M.C., Reeder R.H., Hahn S. Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters. Cell 1992, 69:697-702.
    • (1992) Cell , vol.69 , pp. 697-702
    • Schultz, M.C.1    Reeder, R.H.2    Hahn, S.3
  • 80
    • 84867728469 scopus 로고    scopus 로고
    • Superior thermotolerance of Saccharomyces cerevisiae for efficient bioethanol fermentation can be achieved by overexpression of RSP5 ubiquitin ligase
    • Shahsavarani H., Sugiyama M., Kaneko Y., Chuenchit B., Harashima S. Superior thermotolerance of Saccharomyces cerevisiae for efficient bioethanol fermentation can be achieved by overexpression of RSP5 ubiquitin ligase. Biotechnol Adv 2012, 30:1289-1300.
    • (2012) Biotechnol Adv , vol.30 , pp. 1289-1300
    • Shahsavarani, H.1    Sugiyama, M.2    Kaneko, Y.3    Chuenchit, B.4    Harashima, S.5
  • 81
    • 74549126675 scopus 로고    scopus 로고
    • An overview of second generation biofuel technologies
    • Sims R.E., Mabee W., Saddler J.N., Taylor M. An overview of second generation biofuel technologies. Bioresour Technol 2010, 101:1570-1580.
    • (2010) Bioresour Technol , vol.101 , pp. 1570-1580
    • Sims, R.E.1    Mabee, W.2    Saddler, J.N.3    Taylor, M.4
  • 82
    • 0036250071 scopus 로고    scopus 로고
    • Modulation of gene expression made easy
    • Solem C., Jensen P.R. Modulation of gene expression made easy. Appl Environ Microbiol 2002, 68:2397-2403.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 2397-2403
    • Solem, C.1    Jensen, P.R.2
  • 83
    • 0032600888 scopus 로고    scopus 로고
    • Metabolic fluxes and metabolic engineering
    • Stephanopoulos G. Metabolic fluxes and metabolic engineering. Metab Eng 1999, 1:1-11.
    • (1999) Metab Eng , vol.1 , pp. 1-11
    • Stephanopoulos, G.1
  • 84
    • 43749098984 scopus 로고    scopus 로고
    • Plant genetic engineering for biofuel production: towards affordable cellulosic ethanol
    • Sticklen M.B. Plant genetic engineering for biofuel production: towards affordable cellulosic ethanol. Nat Rev Genet 2008, 9:433-443.
    • (2008) Nat Rev Genet , vol.9 , pp. 433-443
    • Sticklen, M.B.1
  • 85
    • 0030792812 scopus 로고    scopus 로고
    • Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars
    • Takayama S., McGarvey G.J., Wong C.H. Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars. Annu Rev Microbiol 1997, 51:285-310.
    • (1997) Annu Rev Microbiol , vol.51 , pp. 285-310
    • Takayama, S.1    McGarvey, G.J.2    Wong, C.H.3
  • 86
    • 70350158322 scopus 로고    scopus 로고
    • Invariability of central metabolic flux distribution in Shewanella oneidensis MR-1 under environmental or genetic perturbations
    • Tang Y.J., Martin H.G., Deutschbauer A., Feng X., Huang R., Llora X., et al. Invariability of central metabolic flux distribution in Shewanella oneidensis MR-1 under environmental or genetic perturbations. Biotechnol Prog 2009, 25:1254-1259.
    • (2009) Biotechnol Prog , vol.25 , pp. 1254-1259
    • Tang, Y.J.1    Martin, H.G.2    Deutschbauer, A.3    Feng, X.4    Huang, R.5    Llora, X.6
  • 87
    • 50249172768 scopus 로고    scopus 로고
    • Screening of Bacillus subtilis transposon mutants with altered riboflavin production
    • Tannler S., Zamboni N., Kiraly C., Aymerich S., Sauer U. Screening of Bacillus subtilis transposon mutants with altered riboflavin production. Metab Eng 2008, 10:216-226.
    • (2008) Metab Eng , vol.10 , pp. 216-226
    • Tannler, S.1    Zamboni, N.2    Kiraly, C.3    Aymerich, S.4    Sauer, U.5
  • 88
    • 33646542650 scopus 로고    scopus 로고
    • High-throughput screen for poly-3-hydroxybutyrate in Escherichia coli and Synechocystis sp. strain PCC6803
    • Tyo K.E., Zhou H., Stephanopoulos G.N. High-throughput screen for poly-3-hydroxybutyrate in Escherichia coli and Synechocystis sp. strain PCC6803. Appl Environ Microbiol 2006, 72:3412-3417.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 3412-3417
    • Tyo, K.E.1    Zhou, H.2    Stephanopoulos, G.N.3
  • 89
    • 70350141657 scopus 로고    scopus 로고
    • Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803
    • Tyo K.E., Jin Y.S., Espinoza F.A., Stephanopoulos G. Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803. Biotechnol Prog 2009, 25:1236-1243.
    • (2009) Biotechnol Prog , vol.25 , pp. 1236-1243
    • Tyo, K.E.1    Jin, Y.S.2    Espinoza, F.A.3    Stephanopoulos, G.4
  • 90
    • 43049084715 scopus 로고    scopus 로고
    • Biomass to fuels via microbial transformations
    • Wackett L.P. Biomass to fuels via microbial transformations. Curr Opin Chem Biol 2008, 12:187-193.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 187-193
    • Wackett, L.P.1
  • 91
    • 68949161807 scopus 로고    scopus 로고
    • Programming cells by multiplex genome engineering and accelerated evolution
    • Wang H.H., Isaacs F.J., Carr P.A., Sun Z.Z., Xu G., Forest C.R., et al. Programming cells by multiplex genome engineering and accelerated evolution. Nature 2009, 460:894-898.
    • (2009) Nature , vol.460 , pp. 894-898
    • Wang, H.H.1    Isaacs, F.J.2    Carr, P.A.3    Sun, Z.Z.4    Xu, G.5    Forest, C.R.6
  • 94
    • 0035100166 scopus 로고    scopus 로고
    • Whole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogaster
    • Yang H.P., Tanikawa A.Y., Van Voorhies W.A., Silva J.C., Kondrashov A.S. Whole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogaster. Genetics 2001, 157:1257-1265.
    • (2001) Genetics , vol.157 , pp. 1257-1265
    • Yang, H.P.1    Tanikawa, A.Y.2    Van Voorhies, W.A.3    Silva, J.C.4    Kondrashov, A.S.5
  • 95
    • 78951478131 scopus 로고    scopus 로고
    • Annotation-based genome-wide SNP discovery in the large and complex Aegilops tauschii genome using next-generation sequencing without a reference genome sequence
    • You F.M., Huo N., Deal K.R., Gu Y.Q., Luo M.C., McGuire P.E., et al. Annotation-based genome-wide SNP discovery in the large and complex Aegilops tauschii genome using next-generation sequencing without a reference genome sequence. BMC Genomics 2011, 12:59.
    • (2011) BMC Genomics , vol.12 , pp. 59
    • You, F.M.1    Huo, N.2    Deal, K.R.3    Gu, Y.Q.4    Luo, M.C.5    McGuire, P.E.6
  • 96
    • 84862800120 scopus 로고    scopus 로고
    • A molecular transporter engineering approach to improving xylose catabolism in Saccharomyces cerevisiae
    • Young E.M., Comer A.D., Huang H., Alper H.S. A molecular transporter engineering approach to improving xylose catabolism in Saccharomyces cerevisiae. Metab Eng 2012, 14:401-411.
    • (2012) Metab Eng , vol.14 , pp. 401-411
    • Young, E.M.1    Comer, A.D.2    Huang, H.3    Alper, H.S.4
  • 97
    • 77954911807 scopus 로고    scopus 로고
    • Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis
    • Zhuo Y., Zhang W., Chen D., Gao H., Tao J., Liu M., et al. Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis. Proc Natl Acad Sci U S A 2010, 107:11250-11254.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11250-11254
    • Zhuo, Y.1    Zhang, W.2    Chen, D.3    Gao, H.4    Tao, J.5    Liu, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.