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Volumn 314, Issue 5805, 2006, Pages 1565-1568

Engineering yeast transcription machinery for improved ethanol tolerance and production

Author keywords

[No Author keywords available]

Indexed keywords

ETHANOL; GENES; GLUCOSE; MUTAGENESIS; YEAST;

EID: 33845442201     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1131969     Document Type: Article
Times cited : (718)

References (30)
  • 1
    • 33845387785 scopus 로고    scopus 로고
    • thesis, Massachusetts Institute of Technology
    • H. Alper, thesis, Massachusetts Institute of Technology (2006).
    • (2006)
    • Alper, H.1
  • 15
    • 33845460697 scopus 로고    scopus 로고
    • note
    • Materials and methods are available as supporting material on Science Online.
  • 18
    • 33845449903 scopus 로고    scopus 로고
    • note
    • For each gene, a P value for differential expression between the two conditions was calculated, by a t test. To simultaneously test multiple hypotheses, P values were corrected in a false-discovery rate analysis (17). False-discovery rates are commonly used for the analysis of large date sets (such as microarrays), which limits false-positives, akin to a Bonferroni correction. In this case, 366 genes were found to be significantly differentially expressed, at a false-discovery rate of 1%.
  • 21
    • 0001262663 scopus 로고    scopus 로고
    • T. I. Lee et al., Nature 405, 701 (2000).
    • (2000) Nature , vol.405 , pp. 701
    • Lee, T.I.1
  • 30
    • 33845424027 scopus 로고    scopus 로고
    • note
    • We acknowledge financial support of this work by the DuPont-MIT Alliance, the Singapore-MIT Alliance (SMA1), the NIH grant GM035010, and Department of Energy grant DE-FG02-94ER14487. We thank F. Winston for a thoughtful discussion regarding experimental design. Microarray data deposited to the Gene Expression Omnibus database under the accession number GSE5185.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.