Longevity determined by developmental arrest genes in Caenorhabditis elegans

Aging Cell

Volumn 6, Issue 4, 2007, Pages 525-533

  Chen, Di ^a   Pan, Kally Z ^a   Palter, Julia E ^a   Kapahi, Pankaj ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Aging; Antagonistic pleiotropy; C. elegans; Developmental arrest; Mitochondria; mRNA translation

Indexed keywords

INSULIN; MESSENGER RNA; SOMATOMEDIN C;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; DIET RESTRICTION; GENE FUNCTION; GENE IDENTIFICATION; GENE INACTIVATION; GENE ISOLATION; GENETIC CODE; GENETIC EPISTASIS; LIFESPAN; LONGEVITY; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA INTERFERENCE; RNA TRANSLATION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, DEVELOPMENTAL; GENES, HELMINTH; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MUTATION; OXIDATIVE STRESS; RECEPTORS, NICOTINIC; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS;

EID: 34447646492     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00305.x     Document Type: Article

References (46)

1. Alone PV, Dever TE (2006) Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon. J. Biol. Chem. 281, 12636-12644.
2. Arantes-Oliveira N, Berman JR, Kenyon C (2003) Healthy animals with extreme longevity. Science 302, 611.
3. Aravind L, Ponting CP (1998) Homologues of 26S proteasome subunits are regulators of transcription and translation. Protein Sci. 7, 1250-1254.
4. Berdichevsky A, Guarente L (2006) A stress response pathway involving sirtuins, forkheads and 14-3-3 proteins. Cell Cycle 5, 2588-2591.
5. Boehm M, Slack F (2005) A developmental timing microRNA and its target regulate life span in C. elegans. Science 310, 1954-1957.
6. Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
7. de Castro E, Hegi de Castro S, Johnson TE (2004) Isolation of long-lived mutants in Caenorhabditis elegans using selection for resistance to juglone. Free Radic. Biol. Med. 37, 139-145.
8. Curran SP, Ruvkun G (2007) Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet. 3, e56.
9. Dillin A, Crawford DK, Kenyon C (2002a) Timing requirements for insulin/ IGF-1 signaling in C. elegans. Science 298, 830-834.
10. Dillin A, Hsu AL, Arantes-Oliveira N, Lehrer-Graiwer J, Hsin H, Fraser AG, Kamath RS, Ahringer J, Kenyon C (2002b) Rates of behavior and aging specified by mitochondrial function during development. Science 298, 2398-2401.
11. Feng J, Bussiere F, Hekimi S (2001) Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell. 1, 633-644.
12. Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, Edgley ML, Larsen PL, Riddle DL (1998) Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150, 129-155.
13. Hamilton B, Dong Y, Shindo M, Liu W, Odell I, Ruvkun G, Lee SS (2005) A systematic RNAi screen for longevity genes in C. elegans. Genes Dev. 19, 1544-1555.
14. Hansen M, Hsu AL, Dillin A, Kenyon C (2005) New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 1, 119-128.
15. Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95-110.
16. Henderson ST, Bonafe M, Johnson TE (2006) daf-16 protects the nematode Caenorhabditis elegans during food deprivation. J. Gerontol. A Biol. Sci. Med. Sci. 61, 444-460.
17. Hershey JWB, Merrick WC (2000) Pathway and mechanism of initiation of protein synthesis. In: Translational Control. of Gene Expression (N Sonenberg, JWB Hershey, MB Mathews, eds). Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp. 33-88.
18. Hinnebusch AG (2000) Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes. In Translational Control of Gene Expression (Sonenberg N, Hershey JWB, Mathews MB, eds). Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp. 185-244.
19. Jia K, Chen D, Riddle DL (2004) The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131, 3897-3906.
20. Johnson TE, Lithgow GJ, Murakami S (1996) Hypothesis: Interventions that increase the response to stress offer the potential for effective life prolongation and increased health. J. Gerontol. A Biol. Sci. Med. Sci. 51, B392-B395.
21. Joshi-Barve S, De Benedetti A, Rhoads RE (1992) Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF-4E and eIF-4 gamma. J. Biol. Chem. 267, 21038-21043.
22. Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2, RESEARCH0002.
23. Kamath RS, Fraser AG, Dong Y et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature, 421, 231-237.
24. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464.
25. Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946.
26. Lakowski B, Hekimi S (1998) The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 95, 13091-13096.
27. Lee SS, Kennedy S, Tolonen AC, Ruvkun G (2003a) DAF-16 target genes that control C. elegans life-span and metabolism. Science 300, 644-647.
28. Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G (2003b) A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat. Genet. 33, 40-48.
29. Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villen J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A (2006) A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001.
30. Lin K, Dorman JB, Rodan A, Kenyon C (1997) daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322.
31. Lithgow GJ, White TM, Melov S, Johnson TE (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl Acad. Sci. USA 92, 7540-7544.
32. Majumdar R, Bandyopadhyay A, Maitra U (2003) Mammalian translation initiation factor eIF1 functions with eIF1A and eIF3 in the formation of a stable 40 S preinitiation complex. J. Biol. Chem. 278, 6580-6587.
33. Martin GM, Austad SN, Johnson TE (1996) Genetic analysis of ageing: Role of oxidative damage and environmental stresses. Nat. Genet. 13, 25-34.
34. Medawar PB (1952) An Unsolved Problem of Biology. London: H.K. Lewis.
35. Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-283.
36. Nolden M, Ehses S, Koppen M, Bernacchia A, Rugarli EI, Langer T (2005) The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell 123, 277-289.
37. Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999.
38. Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA (2005) JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc. Natl Acad. Sci. USA 102, 4494-4499.
39. Oh SW, Mukhopadhyay A, Dixit BL, Raha T, Green MR, Tissenbaum HA (2006) Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat. Genet. 38, 251-257.
40. Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6, 111-119.
41. Partridge L, Gems D (2006) Beyond the evolutionary theory of ageing, from functional genomics to evo-gero. Trends Ecol. Evol. 21, 334-340.
42. Shi J, Kahle A, Hershey JW, Honchak BM, Warneke JA, Leong SP, Nelson MA (2006) Decreased expression of eukaryotic initiation factor 3f deregulates translation and apoptosis in tumor cells. Oncogene 25, 4923-4936.
43. Syntichaki P, Troulinaki K, Tavernarakis N (2007) eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 445, 922-926.
44. Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410, 227-230.
45. Williams GC (1957) Pleiotropy, natural selection, and evolution of senescence. Evolution 11, 398-411.
46. Wolff S, Ma H, Burch D, Maciel GA, Hunter T, Dillin A (2006) SMK-1, an essential regulator of DAF-16-mediated longevity. Cell 124, 1039-1053.