Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation

NeuroMolecular Medicine

Volumn 15, Issue 3, 2013, Pages 549-569

  Inestrosa, Nibaldo C ^a   Godoy, Juan A ^a   Vargas, Jessica Y ^a   Arrazola, MacArena S ^a   Rios, Juvenal A ^a   Carvajal, Francisco J ^a   Serrano, Felipe G ^a   Farias, Ginny G ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

7 nAChR; A oligomers; Wnt signaling pathway

Indexed keywords

AMYLOID BETA PROTEIN; BETA CATENIN; BUNGAROTOXIN RECEPTOR; NICOTINE; PHOSPHATIDYLINOSITOL 3 KINASE; POSTSYNAPTIC DENSITY PROTEIN 95;

AMNESIA; AMYLOIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVATION; EXCITATORY POSTSYNAPTIC POTENTIAL; MORPHOLOGY; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; RAT; SENILE PLAQUE; SIGNAL TRANSDUCTION; SYNAPTIC IMPAIRMENT; SYNAPTIC TRANSMISSION;

MUS; MUS MUSCULUS; RODENTIA;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANDROSTADIENES; ANIMALS; BETA CATENIN; BUNGAROTOXINS; CELLS, CULTURED; DENDRITES; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURITES; NEURONS; NICOTINE; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PLAQUE, AMYLOID; PRESENILIN-1; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SYNAPSINS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84881476205     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-013-8242-1     Document Type: Article

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