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Volumn 110, Issue 4, 2013, Pages 699-710

Diosmin protects against trichloroethylene-induced renal injury in Wistar rats: Plausible role of p53, Bax and caspases

Author keywords

Chemoprevention; Diosmin; Nephrotoxicity; p53; Trichloroethylene

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; CREATININE; DIOSMIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; KIDNEY INJURY MOLECULE 1; LACTATE DEHYDROGENASE; NITROGEN; PLACEBO; PROTEIN BAX; PROTEIN P53; SUPEROXIDE DISMUTASE; TRICHLOROETHYLENE; UREA;

EID: 84881422085     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512005752     Document Type: Article
Times cited : (64)

References (75)
  • 1
    • 33744789211 scopus 로고    scopus 로고
    • Trichloroethylene: Mechanisms of renal toxicity and renal cancer and relevance to risk assessment
    • Lock EJ & Reed CJ (2006) Trichloroethylene: mechanisms of renal toxicity and renal cancer and relevance to risk assessment. Toxicol Sci 91, 313-331.
    • (2006) Toxicol Sci , vol.91 , pp. 313-331
    • Lock, E.J.1    Reed, C.J.2
  • 3
    • 0036078665 scopus 로고    scopus 로고
    • Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene
    • Bull RJ, Orner GA, Cheng RS, et al. (2002) Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene. Toxicol Appl Pharmacol 182, 55-65.
    • (2002) Toxicol Appl Pharmacol , vol.182 , pp. 55-65
    • Bull, R.J.1    Orner, G.A.2    Cheng, R.S.3
  • 5
    • 33845609615 scopus 로고    scopus 로고
    • Potential health effects of occupational chlorinated solvent exposure
    • Ruder AM (2006) Potential health effects of occupational chlorinated solvent exposure. Ann NY Acad Sci 1076, 207-227.
    • (2006) Ann NY Acad Sci , vol.1076 , pp. 207-227
    • Ruder, A.M.1
  • 6
    • 0036389710 scopus 로고    scopus 로고
    • Metabolism and toxicity of trichloroethylene in epididymis and testis
    • Forkert PG, Lash LH, Nadeau V, et al. (2002) Metabolism and toxicity of trichloroethylene in epididymis and testis. Toxicol Appl Pharmacol 182, 244-254.
    • (2002) Toxicol Appl Pharmacol , vol.182 , pp. 244-254
    • Forkert, P.G.1    Lash, L.H.2    Nadeau, V.3
  • 7
    • 31144460449 scopus 로고    scopus 로고
    • Pulmonary bronchiolar cytotoxicity and formation of dichloroacetyl lysine protein adducts in mice treated with trichloroethylene
    • Forkert PG, Millen B, Lash LH, et al. (2006) Pulmonary bronchiolar cytotoxicity and formation of dichloroacetyl lysine protein adducts in mice treated with trichloroethylene. J Pharmacol Exp Ther 316, 520-529.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 520-529
    • Forkert, P.G.1    Millen, B.2    Lash, L.H.3
  • 8
    • 0025824680 scopus 로고
    • Reactivity of cysteine S-conjugate sulfoxides: Formation of S-[1-chloro-2-(S-glutathionyl)vinyl]-L-cysteine sulfoxide by the reaction of S-(1,2 dichlorovinyl)-L-cysteine sulfoxide with glutathione
    • Sausen PJ & Elfarra AA (1991) Reactivity of cysteine S-conjugate sulfoxides: formation of S-[1-chloro-2-(S-glutathionyl)vinyl]-L-cysteine sulfoxide by the reaction of S-(1,2 dichlorovinyl)-L-cysteine sulfoxide with glutathione. Chem Res Toxicol 4, 655-660.
    • (1991) Chem Res Toxicol , vol.4 , pp. 655-660
    • Sausen, P.J.1    Elfarra, A.A.2
  • 9
    • 0028619861 scopus 로고
    • Role of renal metabolism in risk to toxic chemicals
    • Lash LH (1994) Role of renal metabolism in risk to toxic chemicals. Environ Health Perspect 102, Suppl. 11, 75-79.
    • (1994) Environ Health Perspect , vol.102 , Issue.SUPPL. 11 , pp. 75-79
    • Lash, L.H.1
  • 10
    • 67349244332 scopus 로고    scopus 로고
    • Effect of trichloroethylene (TCE) toxicity on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in kidney and other rat tissues
    • Khan S, Priyamvada S, Khan SA, et al. (2009) Effect of trichloroethylene (TCE) toxicity on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in kidney and other rat tissues. Food Chem Toxicol 47, 1562-1568.
    • (2009) Food Chem Toxicol , vol.47 , pp. 1562-1568
    • Khan, S.1    Priyamvada, S.2    Khan, S.A.3
  • 11
    • 23044508876 scopus 로고    scopus 로고
    • Human skeletal muscles a target organ of trichloroethylene toxicity
    • Vattemi G, Tonin P, Filosto M, et al. (2005) Human skeletal muscles a target organ of trichloroethylene toxicity. JAMA 294, 554-556.
    • (2005) JAMA , vol.294 , pp. 554-556
    • Vattemi, G.1    Tonin, P.2    Filosto, M.3
  • 12
    • 0037101880 scopus 로고    scopus 로고
    • Possible involvement of glutathione and p53 in trichloroethylene-and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells
    • Chen SJ, Wang JL, Chen JH, et al. (2002) Possible involvement of glutathione and p53 in trichloroethylene-and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells. Free Radic Biol Med 33, 464-472.
    • (2002) Free Radic Biol Med , vol.33 , pp. 464-472
    • Chen, S.J.1    Wang, J.L.2    Chen, J.H.3
  • 13
    • 20444459421 scopus 로고    scopus 로고
    • Molecular markers of trichloroethylene-induced toxicity in human kidney cells
    • Lash LH, Putt DA, Hueni SE, et al. (2005) Molecular markers of trichloroethylene-induced toxicity in human kidney cells. Toxicol Appl Pharmacol 206, 157-168.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 157-168
    • Lash, L.H.1    Putt, D.A.2    Hueni, S.E.3
  • 14
    • 65049089754 scopus 로고    scopus 로고
    • Natural compounds for cancer treatment and prevention
    • Nobili S, Lippib D, Witortc E, et al. (2009) Natural compounds for cancer treatment and prevention. Pharmacol Res 59, 365-378.
    • (2009) Pharmacol Res , vol.59 , pp. 365-378
    • Nobili, S.1    Lippib, D.2    Witortc, E.3
  • 15
    • 43749107872 scopus 로고    scopus 로고
    • The role of herbs and spices in cancer prevention
    • Kaefer CM & Milner JA (2008) The role of herbs and spices in cancer prevention. J Nutr Biochem 19, 347-361.
    • (2008) J Nutr Biochem , vol.19 , pp. 347-361
    • Kaefer, C.M.1    Milner, J.A.2
  • 16
    • 33846464175 scopus 로고    scopus 로고
    • Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: Potential involvement of ABCG2
    • Wang X & Morris ME (2007) Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos 35, 268-274.
    • (2007) Drug Metab Dispos , vol.35 , pp. 268-274
    • Wang, X.1    Morris, M.E.2
  • 17
    • 79959941695 scopus 로고    scopus 로고
    • Anticancer properties of flavonoids: Roles in various stages of carcinogenesis
    • Clere N, Faure S, Martinez MC, et al. (2011) Anticancer properties of flavonoids: roles in various stages of carcinogenesis. Cardiovasc Hematol Agents Med Chem 9, 62-77.
    • (2011) Cardiovasc Hematol Agents Med Chem , vol.9 , pp. 62-77
    • Clere, N.1    Faure, S.2    Martinez, M.C.3
  • 18
    • 68449103573 scopus 로고    scopus 로고
    • Flavonoids as anti-inflammatory agents: Implications in cancer and cardiovascular disease
    • Garcia-Lafuente A, Guillamon E, Villares A, et al. (2009) Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease. Inflamm Res 58, 537-552.
    • (2009) Inflamm Res , vol.58 , pp. 537-552
    • Garcia-Lafuente, A.1    Guillamon, E.2    Villares, A.3
  • 19
    • 79960699494 scopus 로고    scopus 로고
    • Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice
    • Fu Z, Zhen W, Yuskavage J, et al. (2011) Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice. Br J Nutr 105, 1218-1225.
    • (2011) Br J Nutr , vol.105 , pp. 1218-1225
    • Fu, Z.1    Zhen, W.2    Yuskavage, J.3
  • 20
    • 56049088324 scopus 로고    scopus 로고
    • Simultaneous manipulation of multiple brain targets by green tea catechins: A potential neuroprotective strategy for Alzheimer and Parkinson diseases
    • Mandel SA, Amit T, Weinreb O, et al. (2008) Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases. CNS Neurosci Ther 14, 352-365.
    • (2008) CNS Neurosci Ther , vol.14 , pp. 352-365
    • Mandel, S.A.1    Amit, T.2    Weinreb, O.3
  • 21
    • 72149114602 scopus 로고    scopus 로고
    • Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study
    • Campanero MA, Escolar M, Garcia-Quetglas P, et al. (2010) Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Pharm Biomed Anal 51, 875-881.
    • (2010) J Pharm Biomed Anal , vol.51 , pp. 875-881
    • Campanero, M.A.1    Escolar, M.2    Garcia-Quetglas, P.3
  • 22
    • 0028036694 scopus 로고
    • Biological effects of hesperidin, a citrus flavonoid (note I): Antiinflammatory and analgesic activity
    • Galati EM, Monforte MT, Kirjavainen S, et al. (1994) Biological effects of hesperidin, a citrus flavonoid (note I): antiinflammatory and analgesic activity. Il Farmaco 49, 709-712.
    • (1994) Il Farmaco , vol.49 , pp. 709-712
    • Galati, E.M.1    Monforte, M.T.2    Kirjavainen, S.3
  • 23
    • 0028199826 scopus 로고
    • Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice
    • Da Silva Emim JA, Oliviera AB & Lapa AJ (1994) Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice. J Pharm Pharmacol 46, 118-122.
    • (1994) J Pharm Pharmacol , vol.46 , pp. 118-122
    • Da Silva Emim, J.A.1    Oliviera, A.B.2    Lapa, A.J.3
  • 24
    • 0023629450 scopus 로고
    • Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2a and thromboxane B2 release and histological changes
    • Damon P, Flandre O, Michel F, et al. (1987) Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2a and thromboxane B2 release and histological changes. Arzneimittel Forschung 37, 1149-1153.
    • (1987) Arzneimittel Forschung , vol.37 , pp. 1149-1153
    • Damon, P.1    Flandre, O.2    Michel, F.3
  • 25
    • 0023832466 scopus 로고
    • Effects of flavonoids on nonenzymatic lipid peroxidation: Structure-activity relationship
    • Ratty AK & Das NP (1988) Effects of flavonoids on nonenzymatic lipid peroxidation: structure-activity relationship. Biochem Med Metab Biol 39, 69-79.
    • (1988) Biochem Med Metab Biol , vol.39 , pp. 69-79
    • Ratty, A.K.1    Das, N.P.2
  • 26
    • 79957939863 scopus 로고    scopus 로고
    • Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-a expression
    • Dholakiya SL & Benzeroual KE (2011) Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-a expression. Toxicol In Vitro 25, 1039-1044.
    • (2011) Toxicol in Vitro , vol.25 , pp. 1039-1044
    • Dholakiya, S.L.1    Benzeroual, K.E.2
  • 27
    • 0032692502 scopus 로고    scopus 로고
    • The effect of flavonoid treatment on the glycation and antioxidant status in type 1 diabetic patients
    • Manuel Y, Keenoy B, Vertommen J, et al. (1999) The effect of flavonoid treatment on the glycation and antioxidant status in type 1 diabetic patients. Diabetes Nutr Metab 12, 256-263.
    • (1999) Diabetes Nutr Metab , vol.12 , pp. 256-263
    • Manuel, Y.1    Keenoy, B.2    Vertommen, J.3
  • 28
    • 14444275051 scopus 로고    scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxideinduced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination
    • Tanaka T, Makita H, Ohnishi M, et al. (1997) Chemoprevention of 4-nitroquinoline 1-oxideinduced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination. Cancer Res 57, 246-252.
    • (1997) Cancer Res , vol.57 , pp. 246-252
    • Tanaka, T.1    Makita, H.2    Ohnishi, M.3
  • 29
    • 0031417008 scopus 로고    scopus 로고
    • Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin
    • Tanaka T, Makita H, Kawabata K, et al. (1997) Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin. Carcinogenesis 18, 957-965.
    • (1997) Carcinogenesis , vol.18 , pp. 957-965
    • Tanaka, T.1    Makita, H.2    Kawabata, K.3
  • 30
    • 6844250963 scopus 로고    scopus 로고
    • Modulation of N-methyl-N-amylnitrosamine-induced rat oesophageal tumourigenesis by dietary feeding of diosmin and hesperidin, both alone and in combination
    • Tanaka T, Makita H, Kawabata K, et al. (1997) Modulation of N-methyl-N-amylnitrosamine-induced rat oesophageal tumourigenesis by dietary feeding of diosmin and hesperidin, both alone and in combination. Carcinogenesis 18, 761-769.
    • (1997) Carcinogenesis , vol.18 , pp. 761-769
    • Tanaka, T.1    Makita, H.2    Kawabata, K.3
  • 31
    • 79959715547 scopus 로고    scopus 로고
    • Chrysin modulates ethanol metabolism in Wistar rats: A promising role against organ toxicities
    • Tahir M & Sultana S (2011) Chrysin modulates ethanol metabolism in Wistar rats: a promising role against organ toxicities. Alcohol 46, 383-392.
    • (2011) Alcohol , vol.46 , pp. 383-392
    • Tahir, M.1    Sultana, S.2
  • 33
    • 0019475281 scopus 로고
    • Cytosolic factors which affect microsomal lipid peroxidation in lung and liver
    • Wright JR, Colby HD & Miles PR (1981) Cytosolic factors which affect microsomal lipid peroxidation in lung and liver. Arch Biochem Biophys 206, 296-304.
    • (1981) Arch Biochem Biophys , vol.206 , pp. 296-304
    • Wright, J.R.1    Colby, H.D.2    Miles, P.R.3
  • 34
    • 0016151122 scopus 로고
    • Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite
    • Jollow DJ, Mitchell JR, Zampaglione N, et al. (1974) Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11, 151-169.
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3
  • 35
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S & Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47, 469-474.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 36
    • 0021154323 scopus 로고
    • Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney: Possible implications in analgesic nephropathy
    • Mohandas J, Marshall JJ, Duggin GG, et al. (1984) Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney: possible implications in analgesic nephropathy. Biochem Pharmacol 33, 1801-1807.
    • (1984) Biochem Pharmacol , vol.33 , pp. 1801-1807
    • Mohandas, J.1    Marshall, J.J.2    Duggin, G.G.3
  • 37
    • 0016808562 scopus 로고
    • Glutathione reductase levels in rat brain
    • Carlberg I & Mannervik B (1975) Glutathione reductase levels in rat brain. J Biol Chem 250, 5475-5479.
    • (1975) J Biol Chem , vol.250 , pp. 5475-5479
    • Carlberg, I.1    Mannervik, B.2
  • 39
    • 0016585158 scopus 로고
    • Indianapolis, IN: The Bobber Merrill Company, Inc
    • Kanter M (1975) Clinical Chemistry. Indianapolis, IN: The Bobber Merrill Company, Inc.
    • (1975) Clinical Chemistry
    • Kanter, M.1
  • 40
    • 0000100285 scopus 로고
    • Endogenous creatinine in serum and urine
    • Hare RS (1950) Endogenous creatinine in serum and urine. Proc Soc Exp Biol Med 74, 148-151.
    • (1950) Proc Soc Exp Biol Med , vol.74 , pp. 148-151
    • Hare, R.S.1
  • 42
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry OH, Rosebrough NJ, Farr A, et al. (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.3
  • 43
    • 33748159235 scopus 로고    scopus 로고
    • Keys scientific issues in the health risk assessment of trichloroethylene
    • Chiu WA, Caldwell JC, Keshava N, et al. (2006) Keys scientific issues in the health risk assessment of trichloroethylene. Environ Health Perspect 114, 1445-1449.
    • (2006) Environ Health Perspect , vol.114 , pp. 1445-1449
    • Chiu, W.A.1    Caldwell, J.C.2    Keshava, N.3
  • 44
    • 0345991616 scopus 로고    scopus 로고
    • Antioxidant flavonols from fruits, vegetables and beverages: Measurements and bioavailability
    • Crozier A, Burns J, Aziz AA, et al. (2000) Antioxidant flavonols from fruits, vegetables and beverages: measurements and bioavailability. Biol Res 33, 79-88.
    • (2000) Biol Res , vol.33 , pp. 79-88
    • Crozier, A.1    Burns, J.2    Aziz, A.A.3
  • 45
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton K Jr E, andaswami C & Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 52, 673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton Jr., K.1    Andaswami C, E.2    Theoharides, T.C.3
  • 46
    • 0034836506 scopus 로고    scopus 로고
    • Flavonoids: A review of probable mechanisms of action and potential applications
    • Nijveldt RJ, van Nood E, van Hoorn DEC, et al. (2001) Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 74, 418-425.
    • (2001) Am J Clin Nutr , vol.74 , pp. 418-425
    • Nijveldt, R.J.1    Van Nood, E.2    Van Hoorn, D.E.C.3
  • 47
    • 0141863402 scopus 로고    scopus 로고
    • Overview of dietary flavonoids: Nomenclature, occurrence and intake
    • Beecher GR (2003) Overview of dietary flavonoids: nomenclature, occurrence and intake. J Nutr 133, 3248S-3254S.
    • (2003) J Nutr , vol.133
    • Beecher, G.R.1
  • 48
    • 3843087535 scopus 로고    scopus 로고
    • Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Postulation of a biosynthetic pathway
    • Del Bano MJ, Lorente J, Castillo J, et al. (2004) Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Postulation of a biosynthetic pathway. J Agric Food Chem 52, 4987-4992.
    • (2004) J Agric Food Chem , vol.52 , pp. 4987-4992
    • Del Bano, M.J.1    Lorente, J.2    Castillo, J.3
  • 50
  • 51
    • 0031588366 scopus 로고    scopus 로고
    • Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4- hydroxybutyl) nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice
    • Yang M, Tanaka T, Hirose Y, et al. (1997) Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice. Int J Cancer 73, 719-724.
    • (1997) Int J Cancer , vol.73 , pp. 719-724
    • Yang, M.1    Tanaka, T.2    Hirose, Y.3
  • 52
    • 0032815147 scopus 로고    scopus 로고
    • Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
    • Kuntz S, Wenzel U & Daniel H (1999) Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur J Nutr 38, 133-142.
    • (1999) Eur J Nutr , vol.38 , pp. 133-142
    • Kuntz, S.1    Wenzel, U.2    Daniel, H.3
  • 53
    • 0024582131 scopus 로고
    • Lipid peroxidation: A possible mechanism of trichloroethylene-induced nephrotoxicity
    • Cojocel C, Beuter W, Müller W, et al. (1989) Lipid peroxidation: a possible mechanism of trichloroethylene-induced nephrotoxicity. Toxicology 55, 131-141.
    • (1989) Toxicology , vol.55 , pp. 131-141
    • Cojocel, C.1    Beuter, W.2    Müller, W.3
  • 54
    • 0033945538 scopus 로고    scopus 로고
    • Mode of action of trichloroethylene for kidney tumorigenesis
    • Lash LH, Parker JC & Scott CS (2000) Mode of action of trichloroethylene for kidney tumorigenesis. Environ Health Perspect 108, 225-240.
    • (2000) Environ Health Perspect , vol.108 , pp. 225-240
    • Lash, L.H.1    Parker, J.C.2    Scott, C.S.3
  • 55
    • 0035891527 scopus 로고    scopus 로고
    • Apoptosis, necrosis, and cell proliferation induced by S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells
    • Lash LH, Hueni SE & Putt SA (2001) Apoptosis, necrosis, and cell proliferation induced by S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells. Toxicol Appl Pharmacol 177, 1-16.
    • (2001) Toxicol Appl Pharmacol , vol.177 , pp. 1-16
    • Lash, L.H.1    Hueni, S.E.2    Putt, S.A.3
  • 56
    • 79952771884 scopus 로고    scopus 로고
    • Some enzymatic/nonenzymatic antioxidants as potential stress biomarkers of trichloroethylene, heavy metal mixture, and ethyl alcohol in rat tissues
    • Tabrez S & Ahmad M (2011) Some enzymatic/nonenzymatic antioxidants as potential stress biomarkers of trichloroethylene, heavy metal mixture, and ethyl alcohol in rat tissues. Environ Toxicol 26, 207-216.
    • (2011) Environ Toxicol , vol.26 , pp. 207-216
    • Tabrez, S.1    Ahmad, M.2
  • 57
    • 0032846843 scopus 로고    scopus 로고
    • Oxidative stress and DNA damage in Fisher rats following acute exposure to trichloroethylene or perchloroethylene
    • Torasson M, Clark J, Dankovic D, et al. (1999) Oxidative stress and DNA damage in Fisher rats following acute exposure to trichloroethylene or perchloroethylene. Toxicology 138, 43-53.
    • (1999) Toxicology , vol.138 , pp. 43-53
    • Torasson, M.1    Clark, J.2    Dankovic, D.3
  • 58
    • 0034545621 scopus 로고    scopus 로고
    • Suppressive effect of curcumin on trichloroethylene-induced oxidative stress
    • Watanabe S & Fukui T (2000) Suppressive effect of curcumin on trichloroethylene-induced oxidative stress. J Nutr Sci Vitaminol 46, 230-234.
    • (2000) J Nutr Sci Vitaminol , vol.46 , pp. 230-234
    • Watanabe, S.1    Fukui, T.2
  • 59
    • 83555162535 scopus 로고    scopus 로고
    • Repeated short-term stress synergizes the ROS signalling through up regulation of NFkB and iNOS expression induced due to combined exposure of trichloroethylene and UVB rays
    • Ali F & Sultana S (2012) Repeated short-term stress synergizes the ROS signalling through up regulation of NFkB and iNOS expression induced due to combined exposure of trichloroethylene and UVB rays. Mol Cell Biochem 360, 133-145.
    • (2012) Mol Cell Biochem , vol.360 , pp. 133-145
    • Ali, F.1    Sultana, S.2
  • 60
    • 34147118099 scopus 로고    scopus 로고
    • Dietary grape seed proanthocyanidins inhibit UVB-induced oxidative stress and activation of mitogen-activated protein kinases and nuclear factor-kappaB signaling in in vivo SKH-1 hairless mice
    • Sharma SD, Meeran SM & Katiyar SK (2007) Dietary grape seed proanthocyanidins inhibit UVB-induced oxidative stress and activation of mitogen-activated protein kinases and nuclear factor-kappaB signaling in in vivo SKH-1 hairless mice. Mol Cancer Ther 6, 995-1005.
    • (2007) Mol Cancer Ther , vol.6 , pp. 995-1005
    • Sharma, S.D.1    Meeran, S.M.2    Katiyar, S.K.3
  • 61
    • 81855185933 scopus 로고    scopus 로고
    • Diosmin ameliorates intestinal injury induced by hepatic ischemia reperfusion in rats
    • Tanrikulu Y, Kismet K, Serin Kilicoglu S, et al. (2011) Diosmin ameliorates intestinal injury induced by hepatic ischemia reperfusion in rats. Bratisl Lek Listy 112, 545-551.
    • (2011) Bratisl Lek Listy , vol.112 , pp. 545-551
    • Tanrikulu, Y.1    Kismet, K.2    Serin Kilicoglu, S.3
  • 62
    • 79960772713 scopus 로고    scopus 로고
    • The effect of a flavonoid fractions diosmin \+ hesperidin on radiation-induced acute proctitis in a rat model
    • Sezer A, Usta U, Kocak Z, et al. (2011) The effect of a flavonoid fractions diosmin \+ hesperidin on radiation-induced acute proctitis in a rat model. J Cancer Res Ther 7, 152-156.
    • (2011) J Cancer Res Ther , vol.7 , pp. 152-156
    • Sezer, A.1    Usta, U.2    Kocak, Z.3
  • 63
    • 84857376217 scopus 로고    scopus 로고
    • Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats
    • Rehman MU & Sultana S (2011) Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats. Mol Cell Biochem 357, 115-124.
    • (2011) Mol Cell Biochem , vol.357 , pp. 115-124
    • Rehman, M.U.1    Sultana, S.2
  • 64
    • 36949014801 scopus 로고    scopus 로고
    • Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium
    • Zhou Y, Vaidya VS, Brown RP, et al. (2008) Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci 101, 159-170.
    • (2008) Toxicol Sci , vol.101 , pp. 159-170
    • Zhou, Y.1    Vaidya, V.S.2    Brown, R.P.3
  • 65
    • 80053644191 scopus 로고    scopus 로고
    • Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways
    • Ahmad ST, Arjumand W, Seth A, et al. (2011) Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicology 290, 69-81.
    • (2011) Toxicology , vol.290 , pp. 69-81
    • Ahmad, S.T.1    Arjumand, W.2    Seth, A.3
  • 66
    • 38549146556 scopus 로고    scopus 로고
    • Assessment of the genotoxicity of trichloroethylene and its metabolite, S-(1,2-dichlorovinyl)-L-cysteine (DCVC), in the comet assay in rat kidney
    • ClayP (2008)Assessment of the genotoxicity of trichloroethylene and its metabolite, S-(1,2-dichlorovinyl)-L-cysteine (DCVC), in the comet assay in rat kidney. Mutagenesis 23, 27-33.
    • (2008) Mutagenesis , vol.23 , pp. 27-33
    • Clay, P.1
  • 67
    • 40849084970 scopus 로고    scopus 로고
    • Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells
    • Hu C, Jiang L, Geng C, et al. (2008) Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells. Mutat Res 652, 88-94.
    • (2008) Mutat Res , vol.652 , pp. 88-94
    • Hu, C.1    Jiang, L.2    Geng, C.3
  • 68
    • 84859209302 scopus 로고    scopus 로고
    • Genotoxicity of trichloroethylene in the natural milieu
    • Tabrez S & Ahmad M (2012) Genotoxicity of trichloroethylene in the natural milieu. Int J Hyg Environ Health 215, 333-338.
    • (2012) Int J Hyg Environ Health , vol.215 , pp. 333-338
    • Tabrez, S.1    Ahmad, M.2
  • 69
    • 84856077868 scopus 로고    scopus 로고
    • A novel role of RUNX3 in the regulation of p53-mediated apoptosis in response to DNA damage
    • Ozaki T, Yamada C & Nakagawara A (2011) A novel role of RUNX3 in the regulation of p53-mediated apoptosis in response to DNA damage. Seikagaku 83, 751-754.
    • (2011) Seikagaku , vol.83 , pp. 751-754
    • Ozaki, T.1    Yamada, C.2    Nakagawara, A.3
  • 70
    • 38349190735 scopus 로고    scopus 로고
    • Versatile functions of p53 protein in multicellular organisms
    • Chumakov PM (2007) Versatile functions of p53 protein in multicellular organisms. Biochemistry (Moscow) 72, 1399-1421.
    • (2007) Biochemistry (Moscow) , vol.72 , pp. 1399-1421
    • Chumakov, P.M.1
  • 71
    • 77949516461 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells
    • Zhang X, De Silva D, Sun B, et al. (2010) Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells. Toxicology 269, 13-23.
    • (2010) Toxicology , vol.269 , pp. 13-23
    • Zhang, X.1    De Silva, D.2    Sun, B.3
  • 73
    • 77953482819 scopus 로고    scopus 로고
    • The p53 response element and transcriptional repression
    • Wang B, Xiao Z, Ko HL, et al. (2010) The p53 response element and transcriptional repression. Cell Cycle 9, 870-879.
    • (2010) Cell Cycle , vol.9 , pp. 870-879
    • Wang, B.1    Xiao, Z.2    Ko, H.L.3
  • 74
    • 48149101956 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells
    • Xu F, Papanayotou I, Putt DA, et al. (2008) Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells. Biochem Pharmacol 76, 552-567.
    • (2008) Biochem Pharmacol , vol.76 , pp. 552-567
    • Xu, F.1    Papanayotou, I.2    Putt, D.A.3
  • 75
    • 5444224997 scopus 로고    scopus 로고
    • 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH
    • Akundi RS, Macho A, Muñoz E, et al. (2004) 1-Trichloromethyl-1,2,3, 4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH. J Neurochem 91, 263-273.
    • (2004) J Neurochem , vol.91 , pp. 263-273
    • Akundi, R.S.1    MacHo, A.2    Muñoz, E.3


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