Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-l-cysteine in primary cultures of human proximal tubular cells

Biochemical Pharmacology

Volumn 76, Issue 4, 2008, Pages 552-567

  Xu, Feng ^a   Papanayotou, Irene ^a   Putt, David A ^a   Wang, Jian ^a   Lash, Lawrence H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase activation; Cell proliferation; Cytotoxicity; FasR; Human proximal tubular cells; Mitochondrial energetics

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 7; CASPASE 8; CYCLOSPORIN A; RUTHENIUM RED; S (1,2 DICHLOROVINYL)CYSTEINE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL LOSS; CELL PROLIFERATION; CELL PROTECTION; CELL RESPIRATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA CONTENT; DNA SYNTHESIS; DRUG ACTIVITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY PROXIMAL TUBULE; MITOCHONDRIAL MEMBRANE POTENTIAL; NECROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

APOPTOSIS; CASPASES; CELL DEATH; CELL PROLIFERATION; CELL RESPIRATION; CELLS, CULTURED; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HAZARDOUS SUBSTANCES; HUMANS; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIA; TIME FACTORS;

EID: 48149101956     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.05.016     Document Type: Article

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