Pulmonary bronchiolar cytotoxicity and formation of dichloroacetyl lysine protein adducts in mice treated with trichloroethylene

Journal of Pharmacology and Experimental Therapeutics

Volumn 316, Issue 2, 2006, Pages 520-529

  Forkert, Poh Gek ^a   Millen, Brandie ^a   Lash, Lawrence H ^b   Putt, David A ^b   Ghanayem, Burhan I ^c  

^a QUEEN S UNIVERSITY   (Canada)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; CYTOCHROME P450 2E1; CYTOCHROME P450 2F2; DICHLOROACETYLLYSINE; LYSINE; OXIDOREDUCTASE; TRICHLOROETHYLENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHIOLE; CELL TYPE; CELLULAR DISTRIBUTION; CLARA CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DISEASE ASSOCIATION; DRUG ACTIVITY; EPITHELIUM CELL; HISTOPATHOLOGY; IMMUNOREACTIVITY; LUNG TOXICITY; MALE; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; BRONCHI; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DICHLOROACETATE; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOHISTOCHEMISTRY; LYSINE; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PROTEIN BINDING; SOLVENTS; TRICHLOROETHYLENE;

EID: 31144460449     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.093062     Document Type: Article

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