Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium

Toxicological Sciences

Volumn 101, Issue 1, 2008, Pages 159-170

  Zhou, Yuzhao ^a   Vaidya, Vishal S ^b   Brown, Ronald P ^a   Zhang, Jun ^c   Rosenzweig, Barry A ^c   Thompson, Karol L ^c   Miller, Terry J ^c   Bonventre, Joseph V ^b   Goering, Peter I ^a  

^a CENTER FOR DEVICES AND RADIOLOGICAL HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Acute kidney injury; Chromium; Gentamicin; Kidney injury molecule 1; Mercury; Nephrotoxicity biomarkers

Indexed keywords

ALANINE AMINOTRANSFERASE; BIOLOGICAL MARKER; CHROMIUM; CREATININE; GALACTOSAMINE; GENTAMICIN; KIDNEY INJURY MOLECULE 1; MEMBRANE PROTEIN; MERCURIC CHLORIDE; MERCURY; N ACETYL BETA GLUCOSAMINIDASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; EXPOSURE; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOREACTIVITY; KIDNEY INJURY; KIDNEY NECROSIS; KIDNEY PARENCHYMA; KIDNEY PROXIMAL TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; PREDICTION; PROTEIN DOMAIN; RAT; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; TISSUE SPECIFICITY; UREA NITROGEN BLOOD LEVEL; URINE LEVEL;

ACETYLGLUCOSAMINE; ANIMALS; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES; CHROMIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; GALACTOSAMINE; GENE EXPRESSION; GENTAMICINS; HEPATITIS, TOXIC; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; MALE; MEMBRANE PROTEINS; MERCURY; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

RATTUS;

EID: 36949014801     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm260     Document Type: Article

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