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Volumn 9, Issue 5, 2013, Pages 303-315

Osteoimmunology: The study of the relationship between the immune system and bone tissue;Osteoinmunología: El estudio de la relación entre el sistema inmune y el tejido óseo

Author keywords

Bone cells; Bone tissue; Immune system; Lymphocytes; Osteoimmunology; Osteoporosis; Rheumatoid arthritis

Indexed keywords

BONE CELL; BONE TISSUE; HEMATOPOIESIS; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; OSTEOIMMUNOLOGY; POSTMENOPAUSE OSTEOPOROSIS; SHORT SURVEY;

EID: 84881376837     PISSN: 1699258X     EISSN: 18851398     Source Type: Journal    
DOI: 10.1016/j.reuma.2013.02.008     Document Type: Short Survey
Times cited : (41)

References (95)
  • 1
    • 84882678344 scopus 로고    scopus 로고
    • Functional anatomy of the musculoskeletal system
    • Elsevier, New York, S. Standring (Ed.)
    • Wigley C. Functional anatomy of the musculoskeletal system. Gray's Anatomy 2008, 81-136. Elsevier, New York. 40a ed. S. Standring (Ed.).
    • (2008) Gray's Anatomy , pp. 81-136
    • Wigley, C.1
  • 2
    • 58149387662 scopus 로고    scopus 로고
    • Normal bone anatomy and physiology
    • Clarke B. Normal bone anatomy and physiology. Clin J Am Soc Nephrol 2008, 3:S131-S139.
    • (2008) Clin J Am Soc Nephrol , vol.3
    • Clarke, B.1
  • 3
    • 62249204372 scopus 로고    scopus 로고
    • Bone metabolism during adolescence: the known, the unknown, and the controversial
    • Harel Z. Bone metabolism during adolescence: the known, the unknown, and the controversial. Adolesc Med State Art Rev 2008, 19:573-591.
    • (2008) Adolesc Med State Art Rev , vol.19 , pp. 573-591
    • Harel, Z.1
  • 4
    • 70349729025 scopus 로고    scopus 로고
    • Modelling and remodelling
    • Elsevier Inc, St. Louis, cap. 1, J. Bilezikian, L.G. Raisz, T.J. Martin (Eds.)
    • Seeman E. Modelling and remodelling. Principles of bone biology 2008, 3-28. Elsevier Inc, St. Louis, cap. 1. 3a ed. J. Bilezikian, L.G. Raisz, T.J. Martin (Eds.).
    • (2008) Principles of bone biology , pp. 3-28
    • Seeman, E.1
  • 5
    • 0034735792 scopus 로고    scopus 로고
    • Bone versus immune system
    • Arron J.R., Choi Y. Bone versus immune system. Nature 2000, 408:535-536.
    • (2000) Nature , vol.408 , pp. 535-536
    • Arron, J.R.1    Choi, Y.2
  • 6
    • 85013817678 scopus 로고    scopus 로고
    • Academic Press, Elsevier Inc, London, J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.)
    • Osteoimmunology 2011, Academic Press, Elsevier Inc, London. J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.).
    • (2011) Osteoimmunology
  • 7
    • 80053988027 scopus 로고    scopus 로고
    • Osteoimmunology and osteoporosis
    • Geusens P., Lems W.F. Osteoimmunology and osteoporosis. Arth Res Ther 2011, 13:242-258.
    • (2011) Arth Res Ther , vol.13 , pp. 242-258
    • Geusens, P.1    Lems, W.F.2
  • 10
    • 79751499788 scopus 로고    scopus 로고
    • Disorders of bone remodeling
    • Feng X., McDonald J.M. Disorders of bone remodeling. Annu Rev Pathol 2011, 6:121-145.
    • (2011) Annu Rev Pathol , vol.6 , pp. 121-145
    • Feng, X.1    McDonald, J.M.2
  • 11
    • 84863875184 scopus 로고    scopus 로고
    • An overview of the regulation of bone remodelling at the cellular level
    • Kular J., Tickner J., Chim S.M., Xuet J. An overview of the regulation of bone remodelling at the cellular level. Clin Biochem 2012, 45:863-873.
    • (2012) Clin Biochem , vol.45 , pp. 863-873
    • Kular, J.1    Tickner, J.2    Chim, S.M.3    Xuet, J.4
  • 12
    • 44849107047 scopus 로고    scopus 로고
    • + antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
    • + antiporter ClC-7 is the primary chloride permeation pathway in lysosomes. Nature 2008, 453:788-792.
    • (2008) Nature , vol.453 , pp. 788-792
    • Graves, A.R.1    Curran, P.K.2    Smith, C.3    Mindell, J.A.4
  • 13
    • 0035951282 scopus 로고    scopus 로고
    • Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
    • Kornak U., Kasper D., Bösl M.R., Kaiser E., Schweizer M., Schulz A., et al. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell 2001, 104:205-215.
    • (2001) Cell , vol.104 , pp. 205-215
    • Kornak, U.1    Kasper, D.2    Bösl, M.R.3    Kaiser, E.4    Schweizer, M.5    Schulz, A.6
  • 14
    • 12344279757 scopus 로고    scopus 로고
    • The chloride channel inhibitor NS3736 prevents bone resorption in ovariectomized rats without changing bone formation
    • Schaller S., Henriksen K., Sveigaard C., Heegaard A.M., Hélix N., Stahlhut M., et al. The chloride channel inhibitor NS3736 prevents bone resorption in ovariectomized rats without changing bone formation. J Bone Miner Res 2004, 19:1144-1153.
    • (2004) J Bone Miner Res , vol.19 , pp. 1144-1153
    • Schaller, S.1    Henriksen, K.2    Sveigaard, C.3    Heegaard, A.M.4    Hélix, N.5    Stahlhut, M.6
  • 15
    • 20144387287 scopus 로고    scopus 로고
    • Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration
    • Kasper D., Planells-Cases R., Fuhrmann J.C., Scheel O., Zeitz O., Ruether K., et al. Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration. EMBO J 2005, 24:1079-1091.
    • (2005) EMBO J , vol.24 , pp. 1079-1091
    • Kasper, D.1    Planells-Cases, R.2    Fuhrmann, J.C.3    Scheel, O.4    Zeitz, O.5    Ruether, K.6
  • 16
    • 33846031926 scopus 로고    scopus 로고
    • The molecular understanding of osteoclast differentiation
    • Asagiri M., Takayanagi H. The molecular understanding of osteoclast differentiation. Bone 2007, 40:251-264.
    • (2007) Bone , vol.40 , pp. 251-264
    • Asagiri, M.1    Takayanagi, H.2
  • 17
    • 80052388933 scopus 로고    scopus 로고
    • OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice
    • Barrow A.D., Raynal N., Andersen T.L., Slatter D.A., Bihan D., Pugh N., et al. OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice. J Clin Invest 2011, 121:3505-3516.
    • (2011) J Clin Invest , vol.121 , pp. 3505-3516
    • Barrow, A.D.1    Raynal, N.2    Andersen, T.L.3    Slatter, D.A.4    Bihan, D.5    Pugh, N.6
  • 18
    • 84863239847 scopus 로고    scopus 로고
    • TREM-2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis
    • Otero K., Shinohara M., Zhao H., Cella M., Gilfillan S., Colucci A., et al. TREM-2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis. J Immunol 2012, 188:2612-2621.
    • (2012) J Immunol , vol.188 , pp. 2612-2621
    • Otero, K.1    Shinohara, M.2    Zhao, H.3    Cella, M.4    Gilfillan, S.5    Colucci, A.6
  • 19
    • 79959412176 scopus 로고    scopus 로고
    • Osteoblasts in osteoporosis: past, emerging, and future anabolic targets
    • Marie P., Kassem M. Osteoblasts in osteoporosis: past, emerging, and future anabolic targets. Eur J Endocrinol 2011, 165:1-10.
    • (2011) Eur J Endocrinol , vol.165 , pp. 1-10
    • Marie, P.1    Kassem, M.2
  • 20
    • 79955034448 scopus 로고    scopus 로고
    • Transcriptional regulation of bone formation
    • Baek W.Y., Kim J.E. Transcriptional regulation of bone formation. Front Biosci 2011, 3:126-135.
    • (2011) Front Biosci , vol.3 , pp. 126-135
    • Baek, W.Y.1    Kim, J.E.2
  • 21
    • 84863040008 scopus 로고    scopus 로고
    • TGF-β and BMP signaling in osteoblast differentiation and bone formation
    • Chen G., Deng C., Li Y.P. TGF-β and BMP signaling in osteoblast differentiation and bone formation. Int J Biol Sci 2012, 8:272-288.
    • (2012) Int J Biol Sci , vol.8 , pp. 272-288
    • Chen, G.1    Deng, C.2    Li, Y.P.3
  • 23
    • 33644975844 scopus 로고    scopus 로고
    • Buried alive: how osteoblasts become osteocytes
    • Franz-Odendaal T.A., Hall B.K., Witten P.E. Buried alive: how osteoblasts become osteocytes. Dev Dyn 2006, 235:176-190.
    • (2006) Dev Dyn , vol.235 , pp. 176-190
    • Franz-Odendaal, T.A.1    Hall, B.K.2    Witten, P.E.3
  • 24
    • 84861592770 scopus 로고    scopus 로고
    • Gap junctions and hemichannels in signal transmission, function and development of bone
    • Batra N., Kar R., Jiang J.X. Gap junctions and hemichannels in signal transmission, function and development of bone. Biochim Biophys Acta 2012, 1818:1909-1918.
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 1909-1918
    • Batra, N.1    Kar, R.2    Jiang, J.X.3
  • 25
    • 84864866257 scopus 로고    scopus 로고
    • Osteocyte regulation of bone mineral: a little give and take
    • Atkins G.J., Findlay D.M. Osteocyte regulation of bone mineral: a little give and take. Osteoporos Int 2012, 23:2067-2079.
    • (2012) Osteoporos Int , vol.23 , pp. 2067-2079
    • Atkins, G.J.1    Findlay, D.M.2
  • 26
    • 84856552724 scopus 로고    scopus 로고
    • Osteocytes: central conductors of bone biology in normal and pathological conditions
    • Neve A., Corrado A., Cantatore F.P. Osteocytes: central conductors of bone biology in normal and pathological conditions. Acta Physiol (Oxf) 2012, 204:317-330.
    • (2012) Acta Physiol (Oxf) , vol.204 , pp. 317-330
    • Neve, A.1    Corrado, A.2    Cantatore, F.P.3
  • 27
    • 77949603251 scopus 로고    scopus 로고
    • Osteocytes and WNT: the mechanical control of bone formation
    • Galli C., Passeri G., Macaluso G.M. Osteocytes and WNT: the mechanical control of bone formation. J Dent Res 2010, 89:331-343.
    • (2010) J Dent Res , vol.89 , pp. 331-343
    • Galli, C.1    Passeri, G.2    Macaluso, G.M.3
  • 30
    • 0035153246 scopus 로고    scopus 로고
    • TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
    • Petit A.R., Ji H., von Stechow D., Muller R., Goldring S.R., Choi Y., et al. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol 2001, 159:1689-1699.
    • (2001) Am J Pathol , vol.159 , pp. 1689-1699
    • Petit, A.R.1    Ji, H.2    von Stechow, D.3    Muller, R.4    Goldring, S.R.5    Choi, Y.6
  • 32
    • 11144355389 scopus 로고    scopus 로고
    • The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcR-γ) regulate development of functional osteoclasts through the Syk tyrosine kinase
    • Mocsai A., Humphrey M.B., van Ziffle J.A., Hu Y., Burghardt A., Spusta S.C., et al. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcR-γ) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad Sci U S A 2004, 101:6158-6163.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6158-6163
    • Mocsai, A.1    Humphrey, M.B.2    van Ziffle, J.A.3    Hu, Y.4    Burghardt, A.5    Spusta, S.C.6
  • 33
    • 65549115862 scopus 로고    scopus 로고
    • Plasticity of CD4+ T cell lineage differentiation
    • Zhou L., Chong M.M., Littman D.R. Plasticity of CD4+ T cell lineage differentiation. Immunity 2009, 30:646-655.
    • (2009) Immunity , vol.30 , pp. 646-655
    • Zhou, L.1    Chong, M.M.2    Littman, D.R.3
  • 34
    • 0034735773 scopus 로고    scopus 로고
    • T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ
    • Takayanagi H., Ogasawara K., Hida S., Chiba T., Murata S., Sato K., et al. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ. Nature 2000, 408:600-605.
    • (2000) Nature , vol.408 , pp. 600-605
    • Takayanagi, H.1    Ogasawara, K.2    Hida, S.3    Chiba, T.4    Murata, S.5    Sato, K.6
  • 35
    • 82155192237 scopus 로고    scopus 로고
    • Regulation of bone by the adaptive immune system in arthritis
    • Okamoto K., Takayanagi H. Regulation of bone by the adaptive immune system in arthritis. Arthritis Res Ther 2011, 13:219-230.
    • (2011) Arthritis Res Ther , vol.13 , pp. 219-230
    • Okamoto, K.1    Takayanagi, H.2
  • 36
    • 0035923727 scopus 로고    scopus 로고
    • Up-regulation of TNF producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo
    • Roggia C., Gao Y., Cenci S., Weitzmann M.N., Toraldo G., Isaia G., et al. Up-regulation of TNF producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci U S A 2001, 98:13960-13965.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13960-13965
    • Roggia, C.1    Gao, Y.2    Cenci, S.3    Weitzmann, M.N.4    Toraldo, G.5    Isaia, G.6
  • 37
    • 0033708837 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alfa
    • Cenci S., Weitzmann M.N., Roggia C., Namba N., Novack D., Woodring J., et al. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alfa. J Clin Invest 2000, 106:1229-1327.
    • (2000) J Clin Invest , vol.106 , pp. 1229-1327
    • Cenci, S.1    Weitzmann, M.N.2    Roggia, C.3    Namba, N.4    Novack, D.5    Woodring, J.6
  • 39
    • 33744779045 scopus 로고    scopus 로고
    • Estrogen regulation of immune cell bone interactions
    • Weitzmann M.N., Pacifici R. Estrogen regulation of immune cell bone interactions. Ann N Y Acad Sci 2006, 1068:256-274.
    • (2006) Ann N Y Acad Sci , vol.1068 , pp. 256-274
    • Weitzmann, M.N.1    Pacifici, R.2
  • 40
    • 84864742224 scopus 로고    scopus 로고
    • The development of denosumab for the treatment of diseases of bone loss and cancer-induced bone destruction
    • Goessl C., Katz L., Dougall W.C., Kostenuik P.J., Zoog H.B., Braun A., et al. The development of denosumab for the treatment of diseases of bone loss and cancer-induced bone destruction. Ann N Y Acad Sci 2012, 1263:29-40.
    • (2012) Ann N Y Acad Sci , vol.1263 , pp. 29-40
    • Goessl, C.1    Katz, L.2    Dougall, W.C.3    Kostenuik, P.J.4    Zoog, H.B.5    Braun, A.6
  • 41
    • 84865446399 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor κB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss
    • Onal M., Xiong J., Chen X., Thostenson J.D., Almeida M., Manolagas S.C., et al. Receptor activator of nuclear factor κB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. J Biol Chem 2012, 287:29851-29860.
    • (2012) J Biol Chem , vol.287 , pp. 29851-29860
    • Onal, M.1    Xiong, J.2    Chen, X.3    Thostenson, J.D.4    Almeida, M.5    Manolagas, S.C.6
  • 42
    • 42049110350 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kappa B ligand and osteoprotegerin regulation of bone remodeling in health and disease
    • Kearns A.E., Khosla S., Kostenuik P.J. Receptor activator of nuclear factor kappa B ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev 2008, 29:155-192.
    • (2008) Endocr Rev , vol.29 , pp. 155-192
    • Kearns, A.E.1    Khosla, S.2    Kostenuik, P.J.3
  • 43
    • 2042545404 scopus 로고    scopus 로고
    • Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor kappa B ligand-mediated osteoclastogenesis
    • Yoneda T., Ishimaru N., Arakaki R., Kobayashi M., Izawa T., Moriyama K., et al. Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor kappa B ligand-mediated osteoclastogenesis. Endocrinology 2004, 145:2384-2391.
    • (2004) Endocrinology , vol.145 , pp. 2384-2391
    • Yoneda, T.1    Ishimaru, N.2    Arakaki, R.3    Kobayashi, M.4    Izawa, T.5    Moriyama, K.6
  • 45
    • 64449083350 scopus 로고    scopus 로고
    • Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis
    • Binder N.B., Niederreiter B., Hoffmann O., Stange R., Pap T., Stuinig T.M., et al. Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. Nat Med 2009, 15:417-424.
    • (2009) Nat Med , vol.15 , pp. 417-424
    • Binder, N.B.1    Niederreiter, B.2    Hoffmann, O.3    Stange, R.4    Pap, T.5    Stuinig, T.M.6
  • 46
    • 63049085423 scopus 로고    scopus 로고
    • Estrogen inhibits RANKL-stimulated osteoclastic differentiation of human monocytes through estrogen and RANKL regulated interaction of estrogen receptor alpha with BCAR1 and TRAF6
    • Robinson L.J., Yaroslavskity B.B., Griswold R.D., Zadorozny E.V., Guo L., Tourkova I.L., et al. Estrogen inhibits RANKL-stimulated osteoclastic differentiation of human monocytes through estrogen and RANKL regulated interaction of estrogen receptor alpha with BCAR1 and TRAF6. Exp Cell Res 2009, 315:1287-1301.
    • (2009) Exp Cell Res , vol.315 , pp. 1287-1301
    • Robinson, L.J.1    Yaroslavskity, B.B.2    Griswold, R.D.3    Zadorozny, E.V.4    Guo, L.5    Tourkova, I.L.6
  • 47
    • 84856148387 scopus 로고    scopus 로고
    • Role of T cells in ovariectomy induced bone loss--revisited
    • Pacifici R. Role of T cells in ovariectomy induced bone loss--revisited. J Bone Miner Res 2012, 27:231-239.
    • (2012) J Bone Miner Res , vol.27 , pp. 231-239
    • Pacifici, R.1
  • 48
    • 0032538566 scopus 로고    scopus 로고
    • Transforming growth factor-B stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells
    • Takai H., Kanematsu M., Yano K., Tsuda E., Higashio K., Ikeda K., et al. Transforming growth factor-B stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells. J Biol Chem 1998, 273:27091-27096.
    • (1998) J Biol Chem , vol.273 , pp. 27091-27096
    • Takai, H.1    Kanematsu, M.2    Yano, K.3    Tsuda, E.4    Higashio, K.5    Ikeda, K.6
  • 49
    • 84881370173 scopus 로고    scopus 로고
    • The role of the immune system in the development of osteoporosis
    • Academic Press, Elsevier Inc, London, cap. 9, J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.)
    • Mödder U.I., Riggs B.L., Khosla S. The role of the immune system in the development of osteoporosis. Osteoimmunology 2011, 270-300. Academic Press, Elsevier Inc, London, cap. 9. J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.).
    • (2011) Osteoimmunology , pp. 270-300
    • Mödder, U.I.1    Riggs, B.L.2    Khosla, S.3
  • 50
    • 77950233518 scopus 로고    scopus 로고
    • Rheumatoid synovitis and pannus
    • Elsevier Ltd, London, M. Hochberg, J. Smolen, M. Weinblatt, M. Weisman (Eds.)
    • Gravallese E.M., Monach P.A. Rheumatoid synovitis and pannus. Rheumatology 2008, 841-865. Elsevier Ltd, London. M. Hochberg, J. Smolen, M. Weinblatt, M. Weisman (Eds.).
    • (2008) Rheumatology , pp. 841-865
    • Gravallese, E.M.1    Monach, P.A.2
  • 51
    • 84860727253 scopus 로고    scopus 로고
    • Bone loss in RA: systemic, periarticular and focal
    • Deal C. Bone loss in RA: systemic, periarticular and focal. Curr Rheumatol Rep 2012, 14:231-237.
    • (2012) Curr Rheumatol Rep , vol.14 , pp. 231-237
    • Deal, C.1
  • 52
    • 80053933763 scopus 로고    scopus 로고
    • The role of the immune system in the bone loss of inflammatory artritis
    • Academic Press, Elsevier Inc, London, cap.10, J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.)
    • Goldring S., Schett G. The role of the immune system in the bone loss of inflammatory artritis. Osteoimmunology 2011, 301-324. Academic Press, Elsevier Inc, London, cap.10. J. Lorenzo, Y. Choi, M. Horowitz, H. Takayanagi (Eds.).
    • (2011) Osteoimmunology , pp. 301-324
    • Goldring, S.1    Schett, G.2
  • 53
    • 79954634320 scopus 로고    scopus 로고
    • Osteoclasts in arthritis and Th-17 cell development
    • Okamoto K., Takayanagi H. Osteoclasts in arthritis and Th-17 cell development. Intern Immunopharmacol 2011, 11:543-548.
    • (2011) Intern Immunopharmacol , vol.11 , pp. 543-548
    • Okamoto, K.1    Takayanagi, H.2
  • 54
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • Miossec P., Kolls J.K. Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov 2012, 10:763-776.
    • (2012) Nat Rev Drug Discov , vol.10 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 56
    • 69349093225 scopus 로고    scopus 로고
    • Interleukin-17 and type 17 helper T cells
    • Miossec P., Korn T., Kuchroo V.K. Interleukin-17 and type 17 helper T cells. N Engl J Med 2009, 361:888-898.
    • (2009) N Engl J Med , vol.361 , pp. 888-898
    • Miossec, P.1    Korn, T.2    Kuchroo, V.K.3
  • 57
    • 75149167993 scopus 로고    scopus 로고
    • Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses
    • Glatigny S., Blaton M.A., Mencher S.K., Mistou S., Lucas B., Fournier C., et al. Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses. Eur J Immunol 2010, 40:460-469.
    • (2010) Eur J Immunol , vol.40 , pp. 460-469
    • Glatigny, S.1    Blaton, M.A.2    Mencher, S.K.3    Mistou, S.4    Lucas, B.5    Fournier, C.6
  • 58
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato K., Suematsu A., Okamoto K., Yamaguchi A., Morishita Y., Kadono Y., et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006, 203:2673-2682.
    • (2006) J Exp Med , vol.203 , pp. 2673-2682
    • Sato, K.1    Suematsu, A.2    Okamoto, K.3    Yamaguchi, A.4    Morishita, Y.5    Kadono, Y.6
  • 59
    • 84868488604 scopus 로고    scopus 로고
    • New developments in osteoimmunology
    • Takayanagi H. New developments in osteoimmunology. Nat Rev Rheumatol 2012, 8:684-689.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 684-689
    • Takayanagi, H.1
  • 60
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • Genovese M.C., van den Bosch F., Roberson S.A., Bojin S., Biagini I.M., Ryan P., et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 2010, 62:929-939.
    • (2010) Arthritis Rheum , vol.62 , pp. 929-939
    • Genovese, M.C.1    van den Bosch, F.2    Roberson, S.A.3    Bojin, S.4    Biagini, I.M.5    Ryan, P.6
  • 61
    • 59549083038 scopus 로고    scopus 로고
    • Interleukin-17 as a drug target in human disease
    • Ivanov S., Lindén A. Interleukin-17 as a drug target in human disease. Trends Pharmacol Sci 2009, 30:95-103.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 95-103
    • Ivanov, S.1    Lindén, A.2
  • 62
    • 84863861008 scopus 로고    scopus 로고
    • Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis
    • Choy E. Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) 2012, 51(Suppl. 5):v3-v11.
    • (2012) Rheumatology (Oxford) , vol.51 , Issue.SUPPL. 5
    • Choy, E.1
  • 63
    • 84868473102 scopus 로고    scopus 로고
    • Bone erosion in RA: mechanisms, diagnosis and treatment
    • Schett G., Gravallese E. Bone erosion in RA: mechanisms, diagnosis and treatment. Nat Rev Rheumatol 2012, 8:656-664.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 656-664
    • Schett, G.1    Gravallese, E.2
  • 64
    • 77951521434 scopus 로고    scopus 로고
    • Repair of erosions occurs almost exclusively in damaged joints without swelling
    • Lukas C., van der Heijde D., Fatenejad S., Landewé R. Repair of erosions occurs almost exclusively in damaged joints without swelling. Ann Rheum Dis 2009, 69:851-855.
    • (2009) Ann Rheum Dis , vol.69 , pp. 851-855
    • Lukas, C.1    van der Heijde, D.2    Fatenejad, S.3    Landewé, R.4
  • 65
    • 70349504171 scopus 로고    scopus 로고
    • Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1-year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure
    • Møller Døhn U., Boonen A., Hetland M.L., Hansen M.S., Knudsen L.S., Hansen A., et al. Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1-year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure. Ann Rheum Dis 2009, 68:1585-1590.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1585-1590
    • Møller Døhn, U.1    Boonen, A.2    Hetland, M.L.3    Hansen, M.S.4    Knudsen, L.S.5    Hansen, A.6
  • 66
    • 84873720321 scopus 로고    scopus 로고
    • Interleukin 6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study
    • Finzel S., Rech J., Schmidt S., Engelke K., Englbrecht M., Schett G. Interleukin 6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study. Ann Rheum Dis 2013, 72:396-400.
    • (2013) Ann Rheum Dis , vol.72 , pp. 396-400
    • Finzel, S.1    Rech, J.2    Schmidt, S.3    Engelke, K.4    Englbrecht, M.5    Schett, G.6
  • 67
    • 80051474129 scopus 로고    scopus 로고
    • Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion
    • Finzel S., Rech J., Schmidt S., Engelke K., Englbrecht M., Stach C., et al. Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion. Ann Rheum Dis 2011, 70:1587-1593.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1587-1593
    • Finzel, S.1    Rech, J.2    Schmidt, S.3    Engelke, K.4    Englbrecht, M.5    Stach, C.6
  • 68
    • 72749102524 scopus 로고    scopus 로고
    • Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis
    • Walsh N.C., Reinwald S., Manning C.A., Condon K.W., Iwata K., Burr D.B., et al. Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res 2009, 24:1572-1585.
    • (2009) J Bone Miner Res , vol.24 , pp. 1572-1585
    • Walsh, N.C.1    Reinwald, S.2    Manning, C.A.3    Condon, K.W.4    Iwata, K.5    Burr, D.B.6
  • 69
    • 80755189018 scopus 로고    scopus 로고
    • The emerging role of Dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling?
    • Daoussis D., Andonopoulos A.P. The emerging role of Dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling?. Semin Arthritis Rheum 2011, 41:170-177.
    • (2011) Semin Arthritis Rheum , vol.41 , pp. 170-177
    • Daoussis, D.1    Andonopoulos, A.P.2
  • 70
    • 84862256948 scopus 로고    scopus 로고
    • Potential role for therapies targeting DKK1, LRP5, and Serotonin in the treatment of osteoporosis
    • Zhang W., Drake W.T. Potential role for therapies targeting DKK1, LRP5, and Serotonin in the treatment of osteoporosis. Curr Osteoporos Rep 2012, 10:93-100.
    • (2012) Curr Osteoporos Rep , vol.10 , pp. 93-100
    • Zhang, W.1    Drake, W.T.2
  • 71
    • 34247274248 scopus 로고    scopus 로고
    • Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin
    • Luo J.L., Tan W., Ricono J.M., Korchynskyi O., Zhang M., Gonias S.L., et al. Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin. Nature 2007, 446:690-694.
    • (2007) Nature , vol.446 , pp. 690-694
    • Luo, J.L.1    Tan, W.2    Ricono, J.M.3    Korchynskyi, O.4    Zhang, M.5    Gonias, S.L.6
  • 72
    • 35648970074 scopus 로고    scopus 로고
    • IkB kinase a kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
    • Cao Y., Luo J.L., Karin M. IkB kinase a kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. Proc Natl Acad Sci U S A 2007, 104:15852-15857.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15852-15857
    • Cao, Y.1    Luo, J.L.2    Karin, M.3
  • 73
    • 79952193038 scopus 로고    scopus 로고
    • Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signaling
    • Tan W., Zhang W., Strasner A., GrivennikovS, Cheng J.Q., Hoffman R.M., et al. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signaling. Nature 2011, 470:548-553.
    • (2011) Nature , vol.470 , pp. 548-553
    • Tan, W.1    Zhang, W.2    Strasner, A.3    Grivennikov, S.4    Cheng, J.Q.5    Hoffman, R.M.6
  • 74
    • 84861854171 scopus 로고    scopus 로고
    • RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis
    • Palafox M., Ferrer I., Pellegrini P., Vila S., Hernandez-Ortega S., Urruticoechea A., et al. RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis. Cancer Res 2012, 72:2879-2888.
    • (2012) Cancer Res , vol.72 , pp. 2879-2888
    • Palafox, M.1    Ferrer, I.2    Pellegrini, P.3    Vila, S.4    Hernandez-Ortega, S.5    Urruticoechea, A.6
  • 75
    • 84861213409 scopus 로고    scopus 로고
    • Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells
    • Beristain A.G., Narala S.R., di Grappa M.A., Khokha R. Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells. J Cell Sci 2012, 125:943-955.
    • (2012) J Cell Sci , vol.125 , pp. 943-955
    • Beristain, A.G.1    Narala, S.R.2    di Grappa, M.A.3    Khokha, R.4
  • 76
    • 0036196305 scopus 로고    scopus 로고
    • Pancreatic lymph node-derived CD4(+) CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals
    • Green E.A., Choi Y., Flavell R.A. Pancreatic lymph node-derived CD4(+) CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity 2002, 16:183-191.
    • (2002) Immunity , vol.16 , pp. 183-191
    • Green, E.A.1    Choi, Y.2    Flavell, R.A.3
  • 77
    • 76949102820 scopus 로고    scopus 로고
    • RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis
    • Totsuka T., Kanai T., Nemoto Y., Tomita T., Okamoto R., Tsuchiya K., et al. RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis. J Immunol 2009, 182:6079-6087.
    • (2009) J Immunol , vol.182 , pp. 6079-6087
    • Totsuka, T.1    Kanai, T.2    Nemoto, Y.3    Tomita, T.4    Okamoto, R.5    Tsuchiya, K.6
  • 78
    • 84867142035 scopus 로고    scopus 로고
    • New insights into osteoclastogenic signaling mechanisms
    • Nakashima T., Hayashi M., Takayanagi H. New insights into osteoclastogenic signaling mechanisms. Trends Endoc Metab 2012, 23:582-590.
    • (2012) Trends Endoc Metab , vol.23 , pp. 582-590
    • Nakashima, T.1    Hayashi, M.2    Takayanagi, H.3
  • 79
    • 84880920106 scopus 로고    scopus 로고
    • RANKL-RANK interaction in immune regulatory systems
    • Akiyama T., Shinzawa M., Akiyama N. RANKL-RANK interaction in immune regulatory systems. World J Orthop 2012, 3:142-150.
    • (2012) World J Orthop , vol.3 , pp. 142-150
    • Akiyama, T.1    Shinzawa, M.2    Akiyama, N.3
  • 81
    • 0028274877 scopus 로고
    • Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor
    • Taichman R.S., Emerson S.G. Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor. J Exp Med 1994, 179:1677-1682.
    • (1994) J Exp Med , vol.179 , pp. 1677-1682
    • Taichman, R.S.1    Emerson, S.G.2
  • 82
    • 84860480506 scopus 로고    scopus 로고
    • Bone marrow niches for hematopoietic stem cells and immune cells
    • Sugiyama T., Nagasawa T. Bone marrow niches for hematopoietic stem cells and immune cells. Inflamm Allergy Drug Targets 2012, 11:201-206.
    • (2012) Inflamm Allergy Drug Targets , vol.11 , pp. 201-206
    • Sugiyama, T.1    Nagasawa, T.2
  • 83
    • 80054087448 scopus 로고    scopus 로고
    • N-cadherin adherens junctions mediate osteogenesis through PI3K signaling
    • Guntur A.R., Rosen C.J., Naski M.C. N-cadherin adherens junctions mediate osteogenesis through PI3K signaling. Bone 2012, 50:54-62.
    • (2012) Bone , vol.50 , pp. 54-62
    • Guntur, A.R.1    Rosen, C.J.2    Naski, M.C.3
  • 84
    • 84555189736 scopus 로고    scopus 로고
    • The bone marrow at the crossroad of blood and immunity
    • Mercier F.E., Ragu C., Scadden D.T. The bone marrow at the crossroad of blood and immunity. Nat Rev Immunol 2011, 12:49-60.
    • (2011) Nat Rev Immunol , vol.12 , pp. 49-60
    • Mercier, F.E.1    Ragu, C.2    Scadden, D.T.3
  • 85
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stemm cell quiescence in the bone marrow niche
    • Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stemm cell quiescence in the bone marrow niche. Cell 2004, 118:149-161.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6
  • 86
    • 33744983304 scopus 로고    scopus 로고
    • Osteoclast degrade endosteal components and promote mobilization of hematopoietic progenitor cells
    • Kollet O., Dar A., Shivtiel S., Kalinkovich A., Lapid K., Sztainberg Y., et al. Osteoclast degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med 2006, 12:657-664.
    • (2006) Nat Med , vol.12 , pp. 657-664
    • Kollet, O.1    Dar, A.2    Shivtiel, S.3    Kalinkovich, A.4    Lapid, K.5    Sztainberg, Y.6
  • 87
    • 84862936378 scopus 로고    scopus 로고
    • Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization
    • Miyamoto K., Yoshida S., Kawasumi M., Hashimoto K., Kimura T., Sato Y., et al. Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. J Exp Med 2011, 208:2175-2181.
    • (2011) J Exp Med , vol.208 , pp. 2175-2181
    • Miyamoto, K.1    Yoshida, S.2    Kawasumi, M.3    Hashimoto, K.4    Kimura, T.5    Sato, Y.6
  • 90
    • 84862001747 scopus 로고    scopus 로고
    • Osteoclast activated FoxP+ CD8+ T-cells supress bone resorption in vitro
    • Buchwald Z.S., Kiesel J.R., DiPaolo R., Pagadala M.S., Aurora R. Osteoclast activated FoxP+ CD8+ T-cells supress bone resorption in vitro. Plos One 2012, 7:e38199. 10.1371/journal.pone.0038199.
    • (2012) Plos One , vol.7
    • Buchwald, Z.S.1    Kiesel, J.R.2    DiPaolo, R.3    Pagadala, M.S.4    Aurora, R.5
  • 91
    • 66949172165 scopus 로고    scopus 로고
    • Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells
    • Kiesel J.R., Buchwald Z.S., Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J Immunol 2009, 182:5477-5487.
    • (2009) J Immunol , vol.182 , pp. 5477-5487
    • Kiesel, J.R.1    Buchwald, Z.S.2    Aurora, R.3
  • 93
    • 81255211982 scopus 로고    scopus 로고
    • Targeting osteoclast-osteoblast communication
    • Cao X. Targeting osteoclast-osteoblast communication. Nat Med 2011, 17:1344-1346.
    • (2011) Nat Med , vol.17 , pp. 1344-1346
    • Cao, X.1
  • 94
    • 84857686973 scopus 로고    scopus 로고
    • Diverse roles for semaphoring-plexin signaling in the immune system
    • Takamatsu H., Kumanogoh A. Diverse roles for semaphoring-plexin signaling in the immune system. Trends Immunol 2012, 33:127-135.
    • (2012) Trends Immunol , vol.33 , pp. 127-135
    • Takamatsu, H.1    Kumanogoh, A.2


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