-
1
-
-
33646889773
-
Bone quality--the material and structural basis of bone strength and fragility
-
10.1056/NEJMra053077, 16723616
-
Seeman E, Delmas PD. Bone quality--the material and structural basis of bone strength and fragility. N Engl J Med 2006, 354:2250-2261. 10.1056/NEJMra053077, 16723616.
-
(2006)
N Engl J Med
, vol.354
, pp. 2250-2261
-
-
Seeman, E.1
Delmas, P.D.2
-
2
-
-
33947583822
-
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems
-
10.1038/nri2062, 17380158
-
Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007, 7:292-304. 10.1038/nri2062, 17380158.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 292-304
-
-
Takayanagi, H.1
-
3
-
-
0023790708
-
Osteoblastic cells are involved in osteoclast formation
-
10.1210/endo-123-5-2600, 2844518
-
Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T. Osteoblastic cells are involved in osteoclast formation. Endocrinology 1988, 123:2600-2602. 10.1210/endo-123-5-2600, 2844518.
-
(1988)
Endocrinology
, vol.123
, pp. 2600-2602
-
-
Takahashi, N.1
Akatsu, T.2
Udagawa, N.3
Sasaki, T.4
Yamaguchi, A.5
Moseley, J.M.6
Martin, T.J.7
Suda, T.8
-
4
-
-
0023928381
-
Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures
-
10.1210/endo-122-4-1373, 3345718
-
Takahashi N, Yamana H, Yoshiki S, Roodman GD, Mundy GR, Jones SJ, Boyde A, Suda T. Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 1988, 122:1373-1382. 10.1210/endo-122-4-1373, 3345718.
-
(1988)
Endocrinology
, vol.122
, pp. 1373-1382
-
-
Takahashi, N.1
Yamana, H.2
Yoshiki, S.3
Roodman, G.D.4
Mundy, G.R.5
Jones, S.J.6
Boyde, A.7
Suda, T.8
-
5
-
-
0033304730
-
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
-
10.1210/er.20.3.345, 10368775
-
Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999, 20:345-357. 10.1210/er.20.3.345, 10368775.
-
(1999)
Endocr Rev
, vol.20
, pp. 345-357
-
-
Suda, T.1
Takahashi, N.2
Udagawa, N.3
Jimi, E.4
Gillespie, M.T.5
Martin, T.J.6
-
6
-
-
0025332897
-
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
-
10.1038/345442a0, 2188141
-
Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H, Sudo T, Shultz LD. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 1990, 345:442-444. 10.1038/345442a0, 2188141.
-
(1990)
Nature
, vol.345
, pp. 442-444
-
-
Yoshida, H.1
Hayashi, S.2
Kunisada, T.3
Ogawa, M.4
Nishikawa, S.5
Okamura, H.6
Sudo, T.7
Shultz, L.D.8
-
7
-
-
0031587848
-
Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice
-
10.1016/S0092-8674(00)80290-1, 9215625
-
Lagasse E, Weissman IL. Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell 1997, 89:1021-1031. 10.1016/S0092-8674(00)80290-1, 9215625.
-
(1997)
Cell
, vol.89
, pp. 1021-1031
-
-
Lagasse, E.1
Weissman, I.L.2
-
8
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
10.1073/pnas.95.7.3597, 19881, 9520411
-
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998, 95:3597-3602. 10.1073/pnas.95.7.3597, 19881, 9520411.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3597-3602
-
-
Yasuda, H.1
Shima, N.2
Nakagawa, N.3
Yamaguchi, K.4
Kinosaki, M.5
Mochizuki, S.6
Tomoyasu, A.7
Yano, K.8
Goto, M.9
Murakami, A.10
Tsuda, E.11
Morinaga, T.12
Higashio, K.13
Udagawa, N.14
Takahashi, N.15
Suda, T.16
-
9
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
10.1016/S0092-8674(00)81569-X, 9568710
-
Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998, 93:165-176. 10.1016/S0092-8674(00)81569-X, 9568710.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
Hsu, H.11
Sullivan, J.12
Hawkins, N.13
Davy, E.14
Capparelli, C.15
Eli, A.16
Qian, Y.X.17
Kaufman, S.18
Sarosi, I.19
Shalhoub, V.20
Senaldi, G.21
Guo, J.22
Delaney, J.23
Boyle, W.J.24
more..
-
10
-
-
0030714605
-
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
-
10.1038/36593, 9367155
-
Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997, 390:175-179. 10.1038/36593, 9367155.
-
(1997)
Nature
, vol.390
, pp. 175-179
-
-
Anderson, D.M.1
Maraskovsky, E.2
Billingsley, W.L.3
Dougall, W.C.4
Tometsko, M.E.5
Roux, E.R.6
Teepe, M.C.7
DuBose, R.F.8
Cosman, D.9
Galibert, L.10
-
11
-
-
14444272043
-
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
-
10.1074/jbc.272.40.25190, 9312132
-
Wong BR, Rho J, Arron J, Robinson E, Orlinick J, Chao M, Kalachikov S, Cayani E, Bartlett FS, Frankel WN, Lee SY, Choi Y. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J Biol Chem 1997, 272:25190-25194. 10.1074/jbc.272.40.25190, 9312132.
-
(1997)
J Biol Chem
, vol.272
, pp. 25190-25194
-
-
Wong, B.R.1
Rho, J.2
Arron, J.3
Robinson, E.4
Orlinick, J.5
Chao, M.6
Kalachikov, S.7
Cayani, E.8
Bartlett, F.S.9
Frankel, W.N.10
Lee, S.Y.11
Choi, Y.12
-
12
-
-
0036218666
-
RANK-L and RANK: T cells, bone loss, and mammalian evolution
-
10.1146/annurev.immunol.20.100301.064753, 11861618
-
Theill LE, Boyle WJ, Penninger JM. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 2002, 20:795-823. 10.1146/annurev.immunol.20.100301.064753, 11861618.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 795-823
-
-
Theill, L.E.1
Boyle, W.J.2
Penninger, J.M.3
-
13
-
-
0031005576
-
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density
-
10.1016/S0092-8674(00)80209-3, 9108485
-
Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997, 89:309-319. 10.1016/S0092-8674(00)80209-3, 9108485.
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
Shimamoto, G.11
DeRose, M.12
Elliott, R.13
Colombero, A.14
Tan, H.L.15
Trail, G.16
Sullivan, J.17
Davy, E.18
Bucay, N.19
Renshaw-Gegg, L.20
Hughes, T.M.21
Hill, D.22
Pattison, W.23
Campbell, P.24
Sander, S.25
Van, G.26
Tarpley, J.27
Derby, P.28
Lee, R.29
Boyle, W.J.30
more..
-
14
-
-
0030989969
-
Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis
-
10.1006/bbrc.1997.6603, 9168977
-
Tsuda E, Goto M, Mochizuki S, Yano K, Kobayashi F, Morinaga T, Higashio K. Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. Biochem Biophys Res Commun 1997, 234:137-142. 10.1006/bbrc.1997.6603, 9168977.
-
(1997)
Biochem Biophys Res Commun
, vol.234
, pp. 137-142
-
-
Tsuda, E.1
Goto, M.2
Mochizuki, S.3
Yano, K.4
Kobayashi, F.5
Morinaga, T.6
Higashio, K.7
-
15
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
10.1038/16852, 9950424
-
Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, Morony S, Oliveirados-Santos AJ, Van G, Itie A, Khoo W, Wakeham A, Dunstan CR, Lacey DL, Mak TW, Boyle WJ, Penninger JM. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999, 397:315-323. 10.1038/16852, 9950424.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
Morony, S.7
Oliveirados-Santos, A.J.8
Van, G.9
Itie, A.10
Khoo, W.11
Wakeham, A.12
Dunstan, C.R.13
Lacey, D.L.14
Mak, T.W.15
Boyle, W.J.16
Penninger, J.M.17
-
16
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
10.1101/gad.13.18.2412, 317030, 10500098
-
Dougall WC, Glaccum M, Charrier K, Rohrbach K, Brasel K, De Smedt T, Daro E, Smith J, Tometsko ME, Maliszewski CR, Armstrong A, Shen V, Bain S, Cosman D, Anderson D, Morrissey PJ, Peschon JJ, Schuh J. RANK is essential for osteoclast and lymph node development. Genes Dev 1999, 13:2412-2424. 10.1101/gad.13.18.2412, 317030, 10500098.
-
(1999)
Genes Dev
, vol.13
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
Rohrbach, K.4
Brasel, K.5
De Smedt, T.6
Daro, E.7
Smith, J.8
Tometsko, M.E.9
Maliszewski, C.R.10
Armstrong, A.11
Shen, V.12
Bain, S.13
Cosman, D.14
Anderson, D.15
Morrissey, P.J.16
Peschon, J.J.17
Schuh, J.18
-
17
-
-
12944262423
-
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
-
10.1073/pnas.97.4.1566, 26475, 10677500
-
Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci USA 2000, 97:1566-1571. 10.1073/pnas.97.4.1566, 26475, 10677500.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1566-1571
-
-
Li, J.1
Sarosi, I.2
Yan, X.Q.3
Morony, S.4
Capparelli, C.5
Tan, H.L.6
McCabe, S.7
Elliott, R.8
Scully, S.9
Van, G.10
Kaufman, S.11
Juan, S.C.12
Sun, Y.13
Tarpley, J.14
Martin, L.15
Christensen, K.16
McCabe, J.17
Kostenuik, P.18
Hsu, H.19
Fletcher, F.20
Dunstan, C.R.21
Lacey, D.L.22
Boyle, W.J.23
more..
-
18
-
-
0032079445
-
Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
-
10.1101/gad.12.9.1260, 316769, 9573043
-
Bucay N, Sarosi I, Dunstan CR, Morony S, Tarpley J, Capparelli C, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, Simonet WS. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 1998, 12:1260-1268. 10.1101/gad.12.9.1260, 316769, 9573043.
-
(1998)
Genes Dev
, vol.12
, pp. 1260-1268
-
-
Bucay, N.1
Sarosi, I.2
Dunstan, C.R.3
Morony, S.4
Tarpley, J.5
Capparelli, C.6
Scully, S.7
Tan, H.L.8
Xu, W.9
Lacey, D.L.10
Boyle, W.J.11
Simonet, W.S.12
-
19
-
-
0032577903
-
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
-
10.1006/bbrc.1998.8697, 9647741
-
Mizuno A, Amizuka N, Irie K, Murakami A, Fujise N, Kanno T, Sato Y, Nakagawa N, Yasuda H, Mochizuki S, Gomibuchi T, Yano K, Shima N, Washida N, Tsuda E, Morinaga T, Higashio K, Ozawa H. Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun 1998, 247:610-615. 10.1006/bbrc.1998.8697, 9647741.
-
(1998)
Biochem Biophys Res Commun
, vol.247
, pp. 610-615
-
-
Mizuno, A.1
Amizuka, N.2
Irie, K.3
Murakami, A.4
Fujise, N.5
Kanno, T.6
Sato, Y.7
Nakagawa, N.8
Yasuda, H.9
Mochizuki, S.10
Gomibuchi, T.11
Yano, K.12
Shima, N.13
Washida, N.14
Tsuda, E.15
Morinaga, T.16
Higashio, K.17
Ozawa, H.18
-
20
-
-
0033987358
-
Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
-
10.1038/71667, 10615125
-
Hughes AE, Ralston SH, Marken J, Bell C, MacPherson H, Wallace RG, van Hul W, Whyte MP, Nakatsuka K, Hovy L, Anderson DM. Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat Genet 2000, 24:45-48. 10.1038/71667, 10615125.
-
(2000)
Nat Genet
, vol.24
, pp. 45-48
-
-
Hughes, A.E.1
Ralston, S.H.2
Marken, J.3
Bell, C.4
MacPherson, H.5
Wallace, R.G.6
van Hul, W.7
Whyte, M.P.8
Nakatsuka, K.9
Hovy, L.10
Anderson, D.M.11
-
21
-
-
0037130183
-
Osteoprotegerin deficiency and juvenile Paget's disease
-
10.1056/NEJMoa013096, 12124406
-
Whyte MP, Obrecht SE, Finnegan PM, Jones JL, Podgornik MN, McAlister WH, Mumm S. Osteoprotegerin deficiency and juvenile Paget's disease. N Engl J Med 2002, 347:175-184. 10.1056/NEJMoa013096, 12124406.
-
(2002)
N Engl J Med
, vol.347
, pp. 175-184
-
-
Whyte, M.P.1
Obrecht, S.E.2
Finnegan, P.M.3
Jones, J.L.4
Podgornik, M.N.5
McAlister, W.H.6
Mumm, S.7
-
22
-
-
34547521058
-
Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL
-
10.1038/ng2076, 17632511
-
Sobacchi C, Frattini A, Guerrini MM, Abinun M, Pangrazio A, Susani L, Bredius R, Mancini G, Cant A, Bishop N, Grabowski P, Del Fattore A, Messina C, Errigo G, Coxon FP, Scott DI, Teti A, Rogers MJ, Vezzoni P, Villa A, Helfrich MH. Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. Nat Genet 2007, 39:960-962. 10.1038/ng2076, 17632511.
-
(2007)
Nat Genet
, vol.39
, pp. 960-962
-
-
Sobacchi, C.1
Frattini, A.2
Guerrini, M.M.3
Abinun, M.4
Pangrazio, A.5
Susani, L.6
Bredius, R.7
Mancini, G.8
Cant, A.9
Bishop, N.10
Grabowski, P.11
Del Fattore, A.12
Messina, C.13
Errigo, G.14
Coxon, F.P.15
Scott, D.I.16
Teti, A.17
Rogers, M.J.18
Vezzoni, P.19
Villa, A.20
Helfrich, M.H.21
more..
-
23
-
-
46349084493
-
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations
-
10.1016/j.ajhg.2008.06.015, 2443850, 18606301
-
Guerrini MM, Sobacchi C, Cassani B, Abinun M, Kilic SS, Pangrazio A, Moratto D, Mazzolari E, Clayton-Smith J, Orchard P, Coxon FP, Helfrich MH, Crockett JC, Mellis D, Vellodi A, Tezcan I, Notarangelo LD, Rogers MJ, Vezzoni P, Villa A, Frattini A. Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am J Hum Genet 2008, 83:64-76. 10.1016/j.ajhg.2008.06.015, 2443850, 18606301.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 64-76
-
-
Guerrini, M.M.1
Sobacchi, C.2
Cassani, B.3
Abinun, M.4
Kilic, S.S.5
Pangrazio, A.6
Moratto, D.7
Mazzolari, E.8
Clayton-Smith, J.9
Orchard, P.10
Coxon, F.P.11
Helfrich, M.H.12
Crockett, J.C.13
Mellis, D.14
Vellodi, A.15
Tezcan, I.16
Notarangelo, L.D.17
Rogers, M.J.18
Vezzoni, P.19
Villa, A.20
Frattini, A.21
more..
-
24
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
10.1101/gad.13.8.1015, 316636, 10215628
-
Lomaga MA, Yeh WC, Sarosi I, Duncan GS, Furlonger C, Ho A, Morony S, Capparelli C, Van G, Kaufman S, van der Heiden A, Itie A, Wakeham A, Khoo W, Sasaki T, Cao Z, Penninger JM, Paige CJ, Lacey DL, Dunstan CR, Boyle WJ, Goeddel DV, Mak TW. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev 1999, 13:1015-1024. 10.1101/gad.13.8.1015, 316636, 10215628.
-
(1999)
Genes Dev
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
Duncan, G.S.4
Furlonger, C.5
Ho, A.6
Morony, S.7
Capparelli, C.8
Van, G.9
Kaufman, S.10
van der Heiden, A.11
Itie, A.12
Wakeham, A.13
Khoo, W.14
Sasaki, T.15
Cao, Z.16
Penninger, J.M.17
Paige, C.J.18
Lacey, D.L.19
Dunstan, C.R.20
Boyle, W.J.21
Goeddel, D.V.22
Mak, T.W.23
more..
-
25
-
-
6544270833
-
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
-
10.1046/j.1365-2443.1999.00265.x, 10421844
-
Naito A, Azuma S, Tanaka S, Miyazaki T, Takaki S, Takatsu K, Nakao K, Nakamura K, Katsuki M, Yamamoto T, Inoue J. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells 1999, 4:353-362. 10.1046/j.1365-2443.1999.00265.x, 10421844.
-
(1999)
Genes Cells
, vol.4
, pp. 353-362
-
-
Naito, A.1
Azuma, S.2
Tanaka, S.3
Miyazaki, T.4
Takaki, S.5
Takatsu, K.6
Nakao, K.7
Nakamura, K.8
Katsuki, M.9
Yamamoto, T.10
Inoue, J.11
-
26
-
-
28544434439
-
Fos/AP-1 proteins in bone and the immune system
-
10.1111/j.0105-2896.2005.00332.x, 16313345
-
Wagner EF, Eferl R. Fos/AP-1 proteins in bone and the immune system. Immunol Rev 2005, 208:126-140. 10.1111/j.0105-2896.2005.00332.x, 16313345.
-
(2005)
Immunol Rev
, vol.208
, pp. 126-140
-
-
Wagner, E.F.1
Eferl, R.2
-
27
-
-
33845539490
-
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
-
Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med 2006, 12:1410-1416.
-
(2006)
Nat Med
, vol.12
, pp. 1410-1416
-
-
Sato, K.1
Suematsu, A.2
Nakashima, T.3
Takemoto-Kimura, S.4
Aoki, K.5
Morishita, Y.6
Asahara, H.7
Ohya, K.8
Yamaguchi, A.9
Takai, T.10
Kodama, T.11
Chatila, T.A.12
Bito, H.13
Takayanagi, H.14
-
28
-
-
34547124586
-
NF-κB p50 and p52 regulate receptor activator of NF-κB ligand (RANKL) and tumor necrosis factorinduced osteoclast precursor differentiation by activating c-Fos and NFATc1
-
10.1074/jbc.M610701200, 17485464
-
Yamashita T, Yao Z, Li F, Zhang Q, Badell IR, Schwarz EM, Takeshita S, Wagner EF, Noda M, Matsuo K, Xing L, Boyce BF. NF-κB p50 and p52 regulate receptor activator of NF-κB ligand (RANKL) and tumor necrosis factorinduced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem 2007, 282:18245-18253. 10.1074/jbc.M610701200, 17485464.
-
(2007)
J Biol Chem
, vol.282
, pp. 18245-18253
-
-
Yamashita, T.1
Yao, Z.2
Li, F.3
Zhang, Q.4
Badell, I.R.5
Schwarz, E.M.6
Takeshita, S.7
Wagner, E.F.8
Noda, M.9
Matsuo, K.10
Xing, L.11
Boyce, B.F.12
-
29
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
10.1016/S1534-5807(02)00369-6, 12479813
-
Takayanagi H, Kim S, Koga T, Nishina H, Isshiki M, Yoshida H, Saiura A, Isobe M, Yokochi T, Inoue J, Wagner EF, Mak TW, Kodama T, Taniguchi T. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 2002, 3:889-901. 10.1016/S1534-5807(02)00369-6, 12479813.
-
(2002)
Dev Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
30
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
10.1084/jem.20051150, 2213228, 16275763
-
Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Serfling E, Takayanagi H. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 2005, 202:1261-1269. 10.1084/jem.20051150, 2213228, 16275763.
-
(2005)
J Exp Med
, vol.202
, pp. 1261-1269
-
-
Asagiri, M.1
Sato, K.2
Usami, T.3
Ochi, S.4
Nishina, H.5
Yoshida, H.6
Morita, I.7
Wagner, E.F.8
Mak, T.W.9
Serfling, E.10
Takayanagi, H.11
-
31
-
-
33646890016
-
Calcineurin/NFAT signaling in osteoblasts regulates bone mass
-
10.1016/j.devcel.2006.04.006, 16740479
-
Winslow MM, Pan M, Starbuck M, Gallo EM, Deng L, Karsenty G, Crabtree GR. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev Cell 2006, 10:771-782. 10.1016/j.devcel.2006.04.006, 16740479.
-
(2006)
Dev Cell
, vol.10
, pp. 771-782
-
-
Winslow, M.M.1
Pan, M.2
Starbuck, M.3
Gallo, E.M.4
Deng, L.5
Karsenty, G.6
Crabtree, G.R.7
-
32
-
-
55849088412
-
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
-
10.1172/JCI35711, 2564610, 18846253
-
Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest 2008, 118:3775-3789. 10.1172/JCI35711, 2564610, 18846253.
-
(2008)
J Clin Invest
, vol.118
, pp. 3775-3789
-
-
Aliprantis, A.O.1
Ueki, Y.2
Sulyanto, R.3
Park, A.4
Sigrist, K.S.5
Sharma, S.M.6
Ostrowski, M.C.7
Olsen, B.R.8
Glimcher, L.H.9
-
33
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
10.1038/nature02444, 15085135
-
Koga T, Inui M, Inoue K, Kim S, Suematsu A, Kobayashi E, Iwata T, Ohnishi H, Matozaki T, Kodama T, Taniguchi T, Takayanagi H, Takai T. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 2004, 428:758-763. 10.1038/nature02444, 15085135.
-
(2004)
Nature
, vol.428
, pp. 758-763
-
-
Koga, T.1
Inui, M.2
Inoue, K.3
Kim, S.4
Suematsu, A.5
Kobayashi, E.6
Iwata, T.7
Ohnishi, H.8
Matozaki, T.9
Kodama, T.10
Taniguchi, T.11
Takayanagi, H.12
Takai, T.13
-
34
-
-
11144355389
-
The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
-
10.1073/pnas.0401602101, 395939, 15073337
-
Mocsai A, Humphrey MB, Van Ziffle JA, Hu Y, Burghardt A, Spusta SC, Majumdar S, Lanier LL, Lowell CA, Nakamura MC. The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc Natl Acad Sci USA 2004, 101:6158-6163. 10.1073/pnas.0401602101, 395939, 15073337.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6158-6163
-
-
Mocsai, A.1
Humphrey, M.B.2
Van Ziffle, J.A.3
Hu, Y.4
Burghardt, A.5
Spusta, S.C.6
Majumdar, S.7
Lanier, L.L.8
Lowell, C.A.9
Nakamura, M.C.10
-
35
-
-
39749180445
-
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals
-
10.1016/j.cell.2007.12.037, 18329366
-
Shinohara M, Koga T, Okamoto K, Sakaguchi S, Arai K, Yasuda H, Takai T, Kodama T, Morio T, Geha RS, Kitamura D, Kurosaki T, Ellmeier W, Takayanagi H. Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell 2008, 132:794-806. 10.1016/j.cell.2007.12.037, 18329366.
-
(2008)
Cell
, vol.132
, pp. 794-806
-
-
Shinohara, M.1
Koga, T.2
Okamoto, K.3
Sakaguchi, S.4
Arai, K.5
Yasuda, H.6
Takai, T.7
Kodama, T.8
Morio, T.9
Geha, R.S.10
Kitamura, D.11
Kurosaki, T.12
Ellmeier, W.13
Takayanagi, H.14
-
36
-
-
0021285154
-
Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint
-
10.1002/art.1780270902, 6236824
-
Bromley M, Woolley DE. Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint. Arthritis Rheum 1984, 27:968-975. 10.1002/art.1780270902, 6236824.
-
(1984)
Arthritis Rheum
, vol.27
, pp. 968-975
-
-
Bromley, M.1
Woolley, D.E.2
-
37
-
-
0031576524
-
A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis
-
10.1006/bbrc.1997.7404, 9388467
-
Takayanagi H, Oda H, Yamamoto S, Kawaguchi H, Tanaka S, Nishikawa T, Koshihara Y. A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis. Biochem Biophys Res Commun 1997, 240:279-286. 10.1006/bbrc.1997.7404, 9388467.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 279-286
-
-
Takayanagi, H.1
Oda, H.2
Yamamoto, S.3
Kawaguchi, H.4
Tanaka, S.5
Nishikawa, T.6
Koshihara, Y.7
-
38
-
-
0034122050
-
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
-
10.1002/1529-0131(200002)43:2<250::AID-ANR3>3.0.CO;2-P, 10693863
-
Gravallese EM, Manning C, Tsay A, Naito A, Pan C, Amento E, Goldring SR. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum 2000, 43:250-258. 10.1002/1529-0131(200002)43:2<250::AID-ANR3>3.0.CO;2-P, 10693863.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 250-258
-
-
Gravallese, E.M.1
Manning, C.2
Tsay, A.3
Naito, A.4
Pan, C.5
Amento, E.6
Goldring, S.R.7
-
39
-
-
0034121039
-
Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
-
10.1002/1529-0131(200002)43:2<259::AID-ANR4>3.0.CO;2-W, 10693864
-
Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, Koshihara Y, Oda H, Nakamura K, Tanaka S. Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000, 43:259-269. 10.1002/1529-0131(200002)43:2<259::AID-ANR4>3.0.CO;2-W, 10693864.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 259-269
-
-
Takayanagi, H.1
Iizuka, H.2
Juji, T.3
Nakagawa, T.4
Yamamoto, A.5
Miyazaki, T.6
Koshihara, Y.7
Oda, H.8
Nakamura, K.9
Tanaka, S.10
-
40
-
-
0035153246
-
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
-
10.1016/S0002-9440(10)63016-7, 1867076, 11696430
-
Pettit AR, Ji H, von Stechow D, Muller R, Goldring SR, Choi Y, Benoist C, Gravallese EM. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol 2001, 159:1689-1699. 10.1016/S0002-9440(10)63016-7, 1867076, 11696430.
-
(2001)
Am J Pathol
, vol.159
, pp. 1689-1699
-
-
Pettit, A.R.1
Ji, H.2
von Stechow, D.3
Muller, R.4
Goldring, S.R.5
Choi, Y.6
Benoist, C.7
Gravallese, E.M.8
-
41
-
-
0036853902
-
Osteoclasts are essential for TNF-α-mediated joint destruction
-
151809, 12438440
-
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Osteoclasts are essential for TNF-α-mediated joint destruction. J Clin Invest 2002, 110:1419-1427. 151809, 12438440.
-
(2002)
J Clin Invest
, vol.110
, pp. 1419-1427
-
-
Redlich, K.1
Hayer, S.2
Ricci, R.3
David, J.P.4
Tohidast-Akrad, M.5
Kollias, G.6
Steiner, G.7
Smolen, J.S.8
Wagner, E.F.9
Schett, G.10
-
42
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
10.1038/46303, 10580503
-
Kong YY, Feige U, Sarosi I, Bolon B, Tafuri A, Morony S, Capparelli C, Li J, Elliott R, McCabe S, Wong T, Campagnuolo G, Moran E, Bogoch ER, Van G, Nguyen LT, Ohashi PS, Lacey DL, Fish E, Boyle WJ, Penninger JM. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999, 402:304-309. 10.1038/46303, 10580503.
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
Bolon, B.4
Tafuri, A.5
Morony, S.6
Capparelli, C.7
Li, J.8
Elliott, R.9
McCabe, S.10
Wong, T.11
Campagnuolo, G.12
Moran, E.13
Bogoch, E.R.14
Van, G.15
Nguyen, L.T.16
Ohashi, P.S.17
Lacey, D.L.18
Fish, E.19
Boyle, W.J.20
Penninger, J.M.21
more..
-
43
-
-
0032739075
-
Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts
-
10.1172/JCI6093, 408475, 10411542
-
Takayanagi H, Juji T, Miyazaki T, Iizuka H, Takahashi T, Isshiki M, Okada M, Tanaka Y, Koshihara Y, Oda H, Kurokawa T, Nakamura K, Tanaka S. Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts. J Clin Invest 1999, 104:137-146. 10.1172/JCI6093, 408475, 10411542.
-
(1999)
J Clin Invest
, vol.104
, pp. 137-146
-
-
Takayanagi, H.1
Juji, T.2
Miyazaki, T.3
Iizuka, H.4
Takahashi, T.5
Isshiki, M.6
Okada, M.7
Tanaka, Y.8
Koshihara, Y.9
Oda, H.10
Kurokawa, T.11
Nakamura, K.12
Tanaka, S.13
-
44
-
-
75049085147
-
Osteoimmunology and the effects of the immune system on bone
-
10.1038/nrrheum.2009.217, 19884898
-
Takayanagi H. Osteoimmunology and the effects of the immune system on bone. Nat Rev Rheumatol 2009, 5:667-676. 10.1038/nrrheum.2009.217, 19884898.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 667-676
-
-
Takayanagi, H.1
-
45
-
-
0033547343
-
Activated T lymphocytes support osteoclast formation in vitro
-
10.1006/bbrc.1999.1623, 10548505
-
Horwood NJ, Kartsogiannis V, Quinn JM, Romas E, Martin TJ, Gillespie MT. Activated T lymphocytes support osteoclast formation in vitro. Biochem Biophys Res Commun 1999, 265:144-150. 10.1006/bbrc.1999.1623, 10548505.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, pp. 144-150
-
-
Horwood, N.J.1
Kartsogiannis, V.2
Quinn, J.M.3
Romas, E.4
Martin, T.J.5
Gillespie, M.T.6
-
46
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
10.1016/j.immuni.2009.05.001, 19464987
-
Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity 2009, 30:646-655. 10.1016/j.immuni.2009.05.001, 19464987.
-
(2009)
Immunity
, vol.30
, pp. 646-655
-
-
Zhou, L.1
Chong, M.M.2
Littman, D.R.3
-
47
-
-
0025348745
-
How important are T cells in chronic rheumatoid synovitis?
-
10.1002/art.1780330602, 2194461
-
Firestein GS, Zvaifler NJ. How important are T cells in chronic rheumatoid synovitis?. Arthritis Rheum 1990, 33:768-773. 10.1002/art.1780330602, 2194461.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 768-773
-
-
Firestein, G.S.1
Zvaifler, N.J.2
-
48
-
-
0034735773
-
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ
-
10.1038/35046102, 11117749
-
Takayanagi H, Ogasawara K, Hida S, Chiba T, Murata S, Sato K, Takaoka A, Yokochi T, Oda H, Tanaka K, Nakamura K, Taniguchi T. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ. Nature 2000, 408:600-605. 10.1038/35046102, 11117749.
-
(2000)
Nature
, vol.408
, pp. 600-605
-
-
Takayanagi, H.1
Ogasawara, K.2
Hida, S.3
Chiba, T.4
Murata, S.5
Sato, K.6
Takaoka, A.7
Yokochi, T.8
Oda, H.9
Tanaka, K.10
Nakamura, K.11
Taniguchi, T.12
-
49
-
-
0031159108
-
High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors
-
Manoury-Schwartz B, Chiocchia G, Bessis N, Abehsira-Amar O, Batteux F, Muller S, Huang S, Boissier MC, Fournier C. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors. J Immunol 1997, 158:5501-5506.
-
(1997)
J Immunol
, vol.158
, pp. 5501-5506
-
-
Manoury-Schwartz, B.1
Chiocchia, G.2
Bessis, N.3
Abehsira-Amar, O.4
Batteux, F.5
Muller, S.6
Huang, S.7
Boissier, M.C.8
Fournier, C.9
-
50
-
-
0031156936
-
Accelerated collagen-induced arthritis in IFN-γ receptor-deficient mice
-
Vermeire K, Heremans H, Vandeputte M, Huang S, Billiau A, Matthys P. Accelerated collagen-induced arthritis in IFN-γ receptor-deficient mice. J Immunol 1997, 158:5507-5513.
-
(1997)
J Immunol
, vol.158
, pp. 5507-5513
-
-
Vermeire, K.1
Heremans, H.2
Vandeputte, M.3
Huang, S.4
Billiau, A.5
Matthys, P.6
-
51
-
-
33748032383
-
Osteoclasts, rheumatoid arthritis, and osteoimmunology
-
10.1097/01.bor.0000231912.24740.a5, 16763464
-
Sato K, Takayanagi H. Osteoclasts, rheumatoid arthritis, and osteoimmunology. Curr Opin Rheumatol 2006, 18:419-426. 10.1097/01.bor.0000231912.24740.a5, 16763464.
-
(2006)
Curr Opin Rheumatol
, vol.18
, pp. 419-426
-
-
Sato, K.1
Takayanagi, H.2
-
52
-
-
34247523141
-
Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation
-
10.1146/annurev.immunol.22.012703.104758, 17291186
-
Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu Rev Immunol 2007, 25:221-242. 10.1146/annurev.immunol.22.012703.104758, 17291186.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 221-242
-
-
Kastelein, R.A.1
Hunter, C.A.2
Cua, D.J.3
-
53
-
-
61949463911
-
IL-17 and Th17 cells
-
10.1146/annurev.immunol.021908.132710, 19132915
-
Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 cells. Annu Rev Immunol 2009, 27:485-517. 10.1146/annurev.immunol.021908.132710, 19132915.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
54
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
10.1084/jem.20061775, 2118166, 17088434
-
Sato K, Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y, Tanaka S, Kodama T, Akira S, Iwakura Y, Cua DJ, Takayanagi H. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006, 203:2673-2682. 10.1084/jem.20061775, 2118166, 17088434.
-
(2006)
J Exp Med
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
Tanaka, S.7
Kodama, T.8
Akira, S.9
Iwakura, Y.10
Cua, D.J.11
Takayanagi, H.12
-
55
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
10.1172/JCI5703, 408356, 10225978
-
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, Saito S, Inoue K, Kamatani N, Gillespie MT, Martin TJ, Suda T. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999, 103:1345-1352. 10.1172/JCI5703, 408356, 10225978.
-
(1999)
J Clin Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
56
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
10.1016/j.cell.2008.05.009, 18510923
-
Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133:775-787. 10.1016/j.cell.2008.05.009, 18510923.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
57
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
-
10.1084/jem.20040165, 2211983, 15280421
-
Ehrenstein MR, Evans JG, Singh A, Moore S, Warnes G, Isenberg DA, Mauri C. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy. J Exp Med 2004, 200:277-285. 10.1084/jem.20040165, 2211983, 15280421.
-
(2004)
J Exp Med
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
Moore, S.4
Warnes, G.5
Isenberg, D.A.6
Mauri, C.7
-
58
-
-
46749125294
-
Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm
-
10.1016/j.jbspin.2008.04.005, 18571969
-
Boissier MC, Assier E, Falgarone G, Bessis N. Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm. Joint Bone Spine 2008, 75:373-375. 10.1016/j.jbspin.2008.04.005, 18571969.
-
(2008)
Joint Bone Spine
, vol.75
, pp. 373-375
-
-
Boissier, M.C.1
Assier, E.2
Falgarone, G.3
Bessis, N.4
-
59
-
-
65849467800
-
Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis
-
Nistala K, Wedderburn LR. Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. Rheumatology (Oxford) 2009, 48:602-606.
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 602-606
-
-
Nistala, K.1
Wedderburn, L.R.2
-
60
-
-
77953639101
-
Regulatory T cells protect from local and systemic bone destruction in arthritis
-
10.4049/jimmunol.0903841, 20483756
-
Zaiss MM, Frey B, Hess A, Zwerina J, Luther J, Nimmerjahn F, Engelke K, Kollias G, Hunig T, Schett G, David JP. Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol 2010, 184:7238-7246. 10.4049/jimmunol.0903841, 20483756.
-
(2010)
J Immunol
, vol.184
, pp. 7238-7246
-
-
Zaiss, M.M.1
Frey, B.2
Hess, A.3
Zwerina, J.4
Luther, J.5
Nimmerjahn, F.6
Engelke, K.7
Kollias, G.8
Hunig, T.9
Schett, G.10
David, J.P.11
-
61
-
-
34247882571
-
Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells
-
10.1016/j.bbrc.2007.04.042, 17462597
-
Kim YG, Lee CK, Nah SS, Mun SH, Yoo B, Moon HB. Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells. Biochem Biophys Res Commun 2007, 357:1046-1052. 10.1016/j.bbrc.2007.04.042, 17462597.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 1046-1052
-
-
Kim, Y.G.1
Lee, C.K.2
Nah, S.S.3
Mun, S.H.4
Yoo, B.5
Moon, H.B.6
-
62
-
-
37149026641
-
Treg cells suppress osteoclast formation: a new link between the immune system and bone
-
10.1002/art.23138, 18050211
-
Zaiss MM, Axmann R, Zwerina J, Polzer K, Guckel E, Skapenko A, Schulze-Koops H, Horwood N, Cope A, Schett G. Treg cells suppress osteoclast formation: a new link between the immune system and bone. Arthritis Rheum 2007, 56:4104-4112. 10.1002/art.23138, 18050211.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4104-4112
-
-
Zaiss, M.M.1
Axmann, R.2
Zwerina, J.3
Polzer, K.4
Guckel, E.5
Skapenko, A.6
Schulze-Koops, H.7
Horwood, N.8
Cope, A.9
Schett, G.10
-
63
-
-
77955373402
-
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation
-
10.1002/art.27535, 20506516
-
Zaiss MM, Sarter K, Hess A, Engelke K, Bohm C, Nimmerjahn F, Voll R, Schett G, David JP. Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum 2010, 62:2328-2338. 10.1002/art.27535, 20506516.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2328-2338
-
-
Zaiss, M.M.1
Sarter, K.2
Hess, A.3
Engelke, K.4
Bohm, C.5
Nimmerjahn, F.6
Voll, R.7
Schett, G.8
David, J.P.9
-
64
-
-
79952467245
-
Estrogen enhances the functions of CD4+CD25+Foxp3+ regulatory T cells that suppress osteoclast differentiation and bone resorption in vitro
-
Luo CY, Wang L, Sun C, Li DJ. Estrogen enhances the functions of CD4+CD25+Foxp3+ regulatory T cells that suppress osteoclast differentiation and bone resorption in vitro. Cell Mol Immunol 2010, 8:50-58.
-
(2010)
Cell Mol Immunol
, vol.8
, pp. 50-58
-
-
Luo, C.Y.1
Wang, L.2
Sun, C.3
Li, D.J.4
-
65
-
-
77955895130
-
B-cell targeted therapies in human autoimmune diseases: an updated perspective
-
10.1111/j.1600-065X.2010.00945.x, 20727041
-
Townsend MJ, Monroe JG, Chan AC. B-cell targeted therapies in human autoimmune diseases: an updated perspective. Immunol Rev 2010, 237:264-283. 10.1111/j.1600-065X.2010.00945.x, 20727041.
-
(2010)
Immunol Rev
, vol.237
, pp. 264-283
-
-
Townsend, M.J.1
Monroe, J.G.2
Chan, A.C.3
-
66
-
-
33745662565
-
B cells move to centre stage: novel opportunities for autoimmune disease treatment
-
10.1038/nrd2085, 16816838
-
Browning JL. B cells move to centre stage: novel opportunities for autoimmune disease treatment. Nat Rev Drug Discov 2006, 5:564-576. 10.1038/nrd2085, 16816838.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 564-576
-
-
Browning, J.L.1
-
67
-
-
0035451466
-
Connection between B lymphocyte and osteoclast differentiation pathways
-
Manabe N, Kawaguchi H, Chikuda H, Miyaura C, Inada M, Nagai R, Nabeshima Y, Nakamura K, Sinclair AM, Scheuermann RH, Kuro-o M. Connection between B lymphocyte and osteoclast differentiation pathways. J Immunol 2001, 167:2625-2631.
-
(2001)
J Immunol
, vol.167
, pp. 2625-2631
-
-
Manabe, N.1
Kawaguchi, H.2
Chikuda, H.3
Miyaura, C.4
Inada, M.5
Nagai, R.6
Nabeshima, Y.7
Nakamura, K.8
Sinclair, A.M.9
Scheuermann, R.H.10
Kuro-o, M.11
-
68
-
-
0034947297
-
Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells
-
10.1002/1521-4141(200107)31:7<2179::AID-IMMU2179>3.0.CO;2-X, 11449372
-
Choi Y, Woo KM, Ko SH, Lee YJ, Park SJ, Kim HM, Kwon BS. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8(+) T cells. Eur J Immunol 2001, 31:2179-2188. 10.1002/1521-4141(200107)31:7<2179::AID-IMMU2179>3.0.CO;2-X, 11449372.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2179-2188
-
-
Choi, Y.1
Woo, K.M.2
Ko, S.H.3
Lee, Y.J.4
Park, S.J.5
Kim, H.M.6
Kwon, B.S.7
-
69
-
-
0034048059
-
B lymphocytes inhibit human osteoclastogenesis by secretion of TGFβ
-
10.1002/(SICI)1097-4644(20000801)78:2<318::AID-JCB13>3.0.CO;2-N, 10842325
-
Weitzmann MN, Cenci S, Haug J, Brown C, DiPersio J, Pacifici R. B lymphocytes inhibit human osteoclastogenesis by secretion of TGFβ. J Cell Biochem 2000, 78:318-324. 10.1002/(SICI)1097-4644(20000801)78:2<318::AID-JCB13>3.0.CO;2-N, 10842325.
-
(2000)
J Cell Biochem
, vol.78
, pp. 318-324
-
-
Weitzmann, M.N.1
Cenci, S.2
Haug, J.3
Brown, C.4
DiPersio, J.5
Pacifici, R.6
-
70
-
-
0344441850
-
B cells activated in the presence of Th1 cytokines inhibit osteoclastogenesis
-
Choi Y, Kim JJ. B cells activated in the presence of Th1 cytokines inhibit osteoclastogenesis. Exp Mol Med 2003, 35:385-392.
-
(2003)
Exp Mol Med
, vol.35
, pp. 385-392
-
-
Choi, Y.1
Kim, J.J.2
-
71
-
-
34247323904
-
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo
-
10.1182/blood-2006-07-037994, 1874582, 17202317
-
Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP, Weitzmann MN. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood 2007, 109:3839-3848. 10.1182/blood-2006-07-037994, 1874582, 17202317.
-
(2007)
Blood
, vol.109
, pp. 3839-3848
-
-
Li, Y.1
Toraldo, G.2
Li, A.3
Yang, X.4
Zhang, H.5
Qian, W.P.6
Weitzmann, M.N.7
-
72
-
-
9144260054
-
Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors
-
Horowitz MC, Xi Y, Pfl ugh DL, Hesslein DG, Schatz DG, Lorenzo JA, Bothwell AL. Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors. J Immunol 2004, 173:6583-6591.
-
(2004)
J Immunol
, vol.173
, pp. 6583-6591
-
-
Horowitz, M.C.1
Xi, Y.2
Pfl ugh, D.L.3
Hesslein, D.G.4
Schatz, D.G.5
Lorenzo, J.A.6
Bothwell, A.L.7
-
73
-
-
0036897349
-
Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency
-
151629, 12464669
-
Weitzmann MN, Roggia C, Toraldo G, Weitzmann L, Pacifici R. Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest 2002, 110:1643-1650. 151629, 12464669.
-
(2002)
J Clin Invest
, vol.110
, pp. 1643-1650
-
-
Weitzmann, M.N.1
Roggia, C.2
Toraldo, G.3
Weitzmann, L.4
Pacifici, R.5
-
75
-
-
0030875168
-
Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency
-
10.1073/pnas.94.17.9360, 23193, 9256487
-
Miyaura C, Onoe Y, Inada M, Maki K, Ikuta K, Ito M, Suda T. Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency. Proc Natl Acad Sci USA 1997, 94:9360-9365. 10.1073/pnas.94.17.9360, 23193, 9256487.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9360-9365
-
-
Miyaura, C.1
Onoe, Y.2
Inada, M.3
Maki, K.4
Ikuta, K.5
Ito, M.6
Suda, T.7
-
76
-
-
0034284296
-
Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines
-
Weitzmann MN, Cenci S, Rifas L, Brown C, Pacifici R. Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines. Blood 2000, 96:1873-1878.
-
(2000)
Blood
, vol.96
, pp. 1873-1878
-
-
Weitzmann, M.N.1
Cenci, S.2
Rifas, L.3
Brown, C.4
Pacifici, R.5
-
77
-
-
0037422560
-
IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor alpha from T cells
-
10.1073/pnas.0136772100, 140902, 12490655
-
Toraldo G, Roggia C, Qian WP, Pacifici R, Weitzmann MN. IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor alpha from T cells. Proc Natl Acad Sci USA 2003, 100:125-130. 10.1073/pnas.0136772100, 140902, 12490655.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 125-130
-
-
Toraldo, G.1
Roggia, C.2
Qian, W.P.3
Pacifici, R.4
Weitzmann, M.N.5
-
78
-
-
0041814592
-
Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesis
-
10.1210/en.2002-221057, 12865334
-
Lee SK, Kalinowski JF, Jastrzebski SL, Puddington L, Lorenzo JA. Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesis. Endocrinology 2003, 144:3524-3531. 10.1210/en.2002-221057, 12865334.
-
(2003)
Endocrinology
, vol.144
, pp. 3524-3531
-
-
Lee, S.K.1
Kalinowski, J.F.2
Jastrzebski, S.L.3
Puddington, L.4
Lorenzo, J.A.5
-
79
-
-
33646248066
-
Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss
-
10.1359/jbmr.060117, 16734384
-
Lee SK, Kalinowski JF, Jacquin C, Adams DJ, Gronowicz G, Lorenzo JA. Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss. J Bone Miner Res 2006, 21:695-702. 10.1359/jbmr.060117, 16734384.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 695-702
-
-
Lee, S.K.1
Kalinowski, J.F.2
Jacquin, C.3
Adams, D.J.4
Gronowicz, G.5
Lorenzo, J.A.6
-
80
-
-
33748788554
-
B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease
-
10.2353/ajpath.2006.060180, 1698808, 16936272
-
Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol 2006, 169:987-998. 10.2353/ajpath.2006.060180, 1698808, 16936272.
-
(2006)
Am J Pathol
, vol.169
, pp. 987-998
-
-
Kawai, T.1
Matsuyama, T.2
Hosokawa, Y.3
Makihira, S.4
Seki, M.5
Karimbux, N.Y.6
Goncalves, R.B.7
Valverde, P.8
Dibart, S.9
Li, Y.P.10
Miranda, L.A.11
Ernst, C.W.12
Izumi, Y.13
Taubman, M.A.14
-
81
-
-
33645283892
-
B cells play an important role in lipopolysaccharide-induced bone resorption
-
10.1007/s00223-005-0149-x, 16467977
-
Kozuka Y, Ozaki Y, Ukai T, Kaneko T, Hara Y. B cells play an important role in lipopolysaccharide-induced bone resorption. Calcif Tissue Int 2006, 78:125-132. 10.1007/s00223-005-0149-x, 16467977.
-
(2006)
Calcif Tissue Int
, vol.78
, pp. 125-132
-
-
Kozuka, Y.1
Ozaki, Y.2
Ukai, T.3
Kaneko, T.4
Hara, Y.5
-
82
-
-
33748588423
-
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
-
10.1016/j.cell.2006.07.035, 16990136
-
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133. 10.1016/j.cell.2006.07.035, 16990136.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
83
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ
-
10.1016/j.immuni.2007.11.016, 2587175, 18164222
-
Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ. Immunity 2008, 28:29-39. 10.1016/j.immuni.2007.11.016, 2587175, 18164222.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
Shah, B.8
Panopoulos, A.D.9
Schluns, K.S.10
Watowich, S.S.11
Tian, Q.12
Jetten, A.M.13
Dong, C.14
-
84
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
10.1126/science.273.5279.1236, 8703060
-
Gelb BD, Shi GP, Chapman HA, Desnick RJ. Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science 1996, 273:1236-1238. 10.1126/science.273.5279.1236, 8703060.
-
(1996)
Science
, vol.273
, pp. 1236-1238
-
-
Gelb, B.D.1
Shi, G.P.2
Chapman, H.A.3
Desnick, R.J.4
-
85
-
-
38849127573
-
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
-
10.1126/science.1150110, 18239127
-
Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H. Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 2008, 319:624-627. 10.1126/science.1150110, 18239127.
-
(2008)
Science
, vol.319
, pp. 624-627
-
-
Asagiri, M.1
Hirai, T.2
Kunigami, T.3
Kamano, S.4
Gober, H.J.5
Okamoto, K.6
Nishikawa, K.7
Latz, E.8
Golenbock, D.T.9
Aoki, K.10
Ohya, K.11
Imai, Y.12
Morishita, Y.13
Miyazono, K.14
Kato, S.15
Saftig, P.16
Takayanagi, H.17
-
86
-
-
57349191215
-
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
-
10.1038/nature07405, 2596276, 18820679
-
Ewald SE, Lee BL, Lau L, Wickliff e KE, Shi GP, Chapman HA, Barton GM. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 2008, 456:658-662. 10.1038/nature07405, 2596276, 18820679.
-
(2008)
Nature
, vol.456
, pp. 658-662
-
-
Ewald, S.E.1
Lee, B.L.2
Lau, L.3
Wickliff e, K.E.4
Shi, G.P.5
Chapman, H.A.6
Barton, G.M.7
-
87
-
-
56349114913
-
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
-
10.1038/ni.1669, 2735466, 18931679
-
Park B, Brinkmann MM, Spooner E, Lee CC, Kim YM, Ploegh HL. Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 2008, 9:1407-1414. 10.1038/ni.1669, 2735466, 18931679.
-
(2008)
Nat Immunol
, vol.9
, pp. 1407-1414
-
-
Park, B.1
Brinkmann, M.M.2
Spooner, E.3
Lee, C.C.4
Kim, Y.M.5
Ploegh, H.L.6
-
88
-
-
0035185895
-
Cathepsin k is a critical protease in synovial fibroblastmediated collagen degradation
-
10.1016/S0002-9440(10)63068-4, 1850593, 11733367
-
Hou WS, Li Z, Gordon RE, Chan K, Klein MJ, Levy R, Keysser M, Keyszer G, Bromme D. Cathepsin k is a critical protease in synovial fibroblastmediated collagen degradation. Am J Pathol 2001, 159:2167-2177. 10.1016/S0002-9440(10)63068-4, 1850593, 11733367.
-
(2001)
Am J Pathol
, vol.159
, pp. 2167-2177
-
-
Hou, W.S.1
Li, Z.2
Gordon, R.E.3
Chan, K.4
Klein, M.J.5
Levy, R.6
Keysser, M.7
Keyszer, G.8
Bromme, D.9
-
89
-
-
77951877914
-
IκBζ regulates TH17 development by cooperating with ROR nuclear receptors
-
10.1038/nature08922, 20383124
-
Okamoto K, Iwai Y, Oh-Hora M, Yamamoto M, Morio T, Aoki K, Ohya K, Jetten AM, Akira S, Muta T, Takayanagi H. IκBζ regulates TH17 development by cooperating with ROR nuclear receptors. Nature 2010, 464:1381-1385. 10.1038/nature08922, 20383124.
-
(2010)
Nature
, vol.464
, pp. 1381-1385
-
-
Okamoto, K.1
Iwai, Y.2
Oh-Hora, M.3
Yamamoto, M.4
Morio, T.5
Aoki, K.6
Ohya, K.7
Jetten, A.M.8
Akira, S.9
Muta, T.10
Takayanagi, H.11
-
90
-
-
33947715520
-
IκB-ζ: an inducible regulator of nuclear factor-κB
-
Muta T. IκB-ζ: an inducible regulator of nuclear factor-κB. Vitam Horm 2006, 74:301-316.
-
(2006)
Vitam Horm
, vol.74
, pp. 301-316
-
-
Muta, T.1
-
91
-
-
3142581432
-
Regulation of Toll/IL-1-receptormediated gene expression by the inducible nuclear protein IκBζ
-
10.1038/nature02738, 15241416
-
Yamamoto M, Yamazaki S, Uematsu S, Sato S, Hemmi H, Hoshino K, Kaisho T, Kuwata H, Takeuchi O, Takeshige K, Saitoh T, Yamaoka S, Yamamoto N, Yamamoto S, Muta T, Takeda K, Akira S. Regulation of Toll/IL-1-receptormediated gene expression by the inducible nuclear protein IκBζ. Nature 2004, 430:218-222. 10.1038/nature02738, 15241416.
-
(2004)
Nature
, vol.430
, pp. 218-222
-
-
Yamamoto, M.1
Yamazaki, S.2
Uematsu, S.3
Sato, S.4
Hemmi, H.5
Hoshino, K.6
Kaisho, T.7
Kuwata, H.8
Takeuchi, O.9
Takeshige, K.10
Saitoh, T.11
Yamaoka, S.12
Yamamoto, N.13
Yamamoto, S.14
Muta, T.15
Takeda, K.16
Akira, S.17
-
92
-
-
34548128307
-
The development of inflammatory TH-17 cells requires interferon-regulatory factor 4
-
Brustle A, Heink S, Huber M, Rosenplanter C, Stadelmann C, Yu P, Arpaia E, Mak TW, Kamradt T, Lohoff M. The development of inflammatory TH-17 cells requires interferon-regulatory factor 4. Nat Immunol 2007, 8:958-966.
-
(2007)
Nat Immunol
, vol.8
, pp. 958-966
-
-
Brustle, A.1
Heink, S.2
Huber, M.3
Rosenplanter, C.4
Stadelmann, C.5
Yu, P.6
Arpaia, E.7
Mak, T.W.8
Kamradt, T.9
Lohoff, M.10
-
93
-
-
54549100120
-
Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells
-
Zhang F, Meng G, Strober W. Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells. Nat Immunol 2008, 9:1297-1306.
-
(2008)
Nat Immunol
, vol.9
, pp. 1297-1306
-
-
Zhang, F.1
Meng, G.2
Strober, W.3
-
94
-
-
34147138648
-
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
-
Akimzhanov AM, Yang XO, Dong C. Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J Biol Chem 2007, 282:5969-5972.
-
(2007)
J Biol Chem
, vol.282
, pp. 5969-5972
-
-
Akimzhanov, A.M.1
Yang, X.O.2
Dong, C.3
-
95
-
-
57649188886
-
New complexities in helper T cell fate determination and the implications for autoimmune diseases
-
10.1007/s10165-008-0099-z, 2596867, 18679768
-
Takatori H, Kanno Y, Chen Z, O'Shea JJ. New complexities in helper T cell fate determination and the implications for autoimmune diseases. Mod Rheumatol 2008, 18:533-541. 10.1007/s10165-008-0099-z, 2596867, 18679768.
-
(2008)
Mod Rheumatol
, vol.18
, pp. 533-541
-
-
Takatori, H.1
Kanno, Y.2
Chen, Z.3
O'Shea, J.J.4
-
96
-
-
65549135115
-
Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody
-
10.1002/biof.9, 19319845
-
Mihara M, Ohsugi Y, Kishimoto T. Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody. Biofactors 2009, 35:47-51. 10.1002/biof.9, 19319845.
-
(2009)
Biofactors
, vol.35
, pp. 47-51
-
-
Mihara, M.1
Ohsugi, Y.2
Kishimoto, T.3
-
97
-
-
42649106556
-
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
-
10.1038/nature06881, 18362914
-
Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 2008, 453:106-109. 10.1038/nature06881, 18362914.
-
(2008)
Nature
, vol.453
, pp. 106-109
-
-
Veldhoen, M.1
Hirota, K.2
Westendorf, A.M.3
Buer, J.4
Dumoutier, L.5
Renauld, J.C.6
Stockinger, B.7
-
98
-
-
42649095378
-
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
-
10.1038/nature06880, 18362915
-
Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E, Caccamo M, Oukka M, Weiner HL. Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor. Nature 2008, 453:65-71. 10.1038/nature06880, 18362915.
-
(2008)
Nature
, vol.453
, pp. 65-71
-
-
Quintana, F.J.1
Basso, A.S.2
Iglesias, A.H.3
Korn, T.4
Farez, M.F.5
Bettelli, E.6
Caccamo, M.7
Oukka, M.8
Weiner, H.L.9
-
99
-
-
67651001561
-
The AP-1 transcription factor Batf controls TH17 differentiation
-
2716014, 19578362
-
Schraml BU, Hildner K, Ise W, Lee WL, Smith WA, Solomon B, Sahota G, Sim J, Mukasa R, Cemerski S, Hatton RD, Stormo GD, Weaver CT, Russell JH, Murphy TL, Murphy KM. The AP-1 transcription factor Batf controls TH17 differentiation. Nature 2009, 460:405-409. 2716014, 19578362.
-
(2009)
Nature
, vol.460
, pp. 405-409
-
-
Schraml, B.U.1
Hildner, K.2
Ise, W.3
Lee, W.L.4
Smith, W.A.5
Solomon, B.6
Sahota, G.7
Sim, J.8
Mukasa, R.9
Cemerski, S.10
Hatton, R.D.11
Stormo, G.D.12
Weaver, C.T.13
Russell, J.H.14
Murphy, T.L.15
Murphy, K.M.16
|