The chloride channel inhibitor N53736 prevents bone resorption in ovariectomized rats without changing bone formation

Journal of Bone and Mineral Research

Volumn 19, Issue 7, 2004, Pages 1144-1153

  Schaller, Sophie ^a,b   Henriksen, Kim ^a,b   Sveigaard, Christina ^a,b   Heegaard, Anne Marie ^a,b   Hélix, Nathalie ^c   Stahlhut, Martin ^a,b   Ovejero, Maria C ^a,b   Johansen, Jens V ^a,b   Solberg, Helene ^a,b   Andersen, Thomas L ^a,b   Hougaard, Dorit ^d   Berryman, Mark ^e   Shiødt, Christine B ^a,b   Sørensen, Bjørn H ^f   Lichtenberg, Jens ^c   Christophersen, Palle ^c   Foged, Niels T ^a,b   Delaissé, Jean Marie ^a,b   Engsig, Michael T ^a,b   Karsdal, Morten A ^a,b  

^a NORDIC BIOSCIENCE A S   (Denmark)

^b CENTER FOR CLINICAL AND BASIC RESEARCH   (Denmark)

^c Neuroseach A/S   (Denmark)

^d Rigshospitalet   (Denmark)

^e OHIO UNIVERSITY   (United States)

^f Azign Bioscience A/S   (Denmark)

Author keywords

Acidification; Autosomal dominant osteopetrosis II; Bone; Chloride channel; Osteoclast; Osteoporosis

Indexed keywords

ANION CHANNEL; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; N 53736; UNCLASSIFIED DRUG; CLC 1 CHANNEL; CLC-1 CHANNEL; CLCN7 PROTEIN, HUMAN; N53736; TETRAZOLE DERIVATIVE;

APPENDIX; ARTICLE; BONE TURNOVER; DRUG EFFECT; ELECTROPHYSIOLOGY; FEMALE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; OVARIECTOMY; OVARY; PREDICTION; PURKINJE CELL; RAT; ANIMAL; BONE DEVELOPMENT; CELL CULTURE; COATED PIT; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; BONE RESORPTION; CELLS, CULTURED; CHLORIDE CHANNELS; COATED PITS, CELL-MEMBRANE; FEMALE; GENE EXPRESSION PROFILING; HUMANS; OSTEOCLASTS; OSTEOGENESIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; TETRAZOLES; TISSUE DISTRIBUTION;

EID: 12344279757     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.040302     Document Type: Article

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