Potential role for therapies targeting DKK1, LRP5, and serotonin in the treatment of osteoporosis

Current Osteoporosis Reports

Volumn 10, Issue 1, 2012, Pages 93-100

  Zhang, Wei ^a   Drake, Matthew T ^a  

^a Information Technology   (United States)

Author keywords

Dickhopf1 (DKK1); Low density lipoprotein receptor related protein 5 (LRP5); Osteoporosis; Serotonin

Indexed keywords

AXIN; BETA CATENIN; DICKKOPF 1 PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; PARATHYROID HORMONE[1-34]; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRYPTOPHAN HYDROXYLASE 2; DKK1 PROTEIN, HUMAN; LRP5 PROTEIN, HUMAN; NEUTRALIZING ANTIBODY; SIGNAL PEPTIDE;

ARTICLE; CELLULAR DISTRIBUTION; FRACTURE; GENE; GENE DELETION; HUMAN; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5 GENE; MISSENSE MUTATION; MULTIPLE MYELOMA; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; PATHOGENESIS; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; RHEUMATOID ARTHRITIS; TRANSCRIPTION REGULATION; WNT SIGNALING PATHWAY; ANIMAL; BONE; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

ANIMALS; ANTIBODIES, NEUTRALIZING; BONE AND BONES; BONE RESORPTION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; OSTEOBLASTS; OSTEOPOROSIS; SEROTONIN; WNT SIGNALING PATHWAY;

EID: 84862256948     PISSN: 15441873     EISSN: 15442241     Source Type: Journal    
DOI: 10.1007/s11914-011-0086-8     Document Type: Article

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