-
1
-
-
77953259922
-
RANK-Fc inhibits malignancy via inhibiting ERK activation and evoking caspase-3-mediated anoikis in human osteosarcoma cells
-
Akiyama, T., Choong, P. F. M. and Dass, C. R. (2010). RANK-Fc inhibits malignancy via inhibiting ERK activation and evoking caspase-3-mediated anoikis in human osteosarcoma cells. Clin. Exp. Metastasis 27, 207-215.
-
(2010)
Clin. Exp. Metastasis
, vol.27
, pp. 207-215
-
-
Akiyama, T.1
Choong, P.F.M.2
Dass, C.R.3
-
2
-
-
0030714605
-
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
-
Anderson, D. M., Maraskovsky, E., Billingsley, W. L., Dougall, W. C., Tometsko, M. E., Roux, E. R., Teepe, M. C., DuBose, R. F., Cosman, D. and Galibert, L. (1997). A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390, 175-179.
-
(1997)
Nature
, vol.390
, pp. 175-179
-
-
Anderson, D.M.1
Maraskovsky, E.2
Billingsley, W.L.3
Dougall, W.C.4
Tometsko, M.E.5
Roux, E.R.6
Teepe, M.C.7
DuBose, R.F.8
Cosman, D.9
Galibert, L.10
-
3
-
-
37449004858
-
RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes
-
Armstrong, A. P., Miller, R. E., Jones, J. C., Zhang, J., Keller, E. T. and Dougall, W. C. (2008). RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes. Prostate 68, 92-104.
-
(2008)
Prostate
, vol.68
, pp. 92-104
-
-
Armstrong, A.P.1
Miller, R.E.2
Jones, J.C.3
Zhang, J.4
Keller, E.T.5
Dougall, W.C.6
-
4
-
-
9444251067
-
Integrin alphav-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen
-
Bao, W. and Strömblad, S. (2004). Integrin alphav-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen. J. Cell Biol. 167, 745-756.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 745-756
-
-
Bao, W.1
Stromblad, S.2
-
5
-
-
79954548550
-
Regulated expression of ADAMTS- 12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?
-
Beristain, A. G., Zhu, H. and Leung, P. C. (2011). Regulated expression of ADAMTS- 12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion? PLoS ONE 6, e8473.
-
(2011)
PLoS ONE
, vol.6
-
-
Beristain, A.G.1
Zhu, H.2
Leung, P.C.3
-
6
-
-
34548454049
-
Biology of RANK, RANKL, and osteoprotegerin
-
Boyce, B. F. and Xing, L. (2007). Biology of RANK, RANKL, and osteoprotegerin. Arthritis Res. Ther. 9 Suppl. 1, S1
-
(2007)
Arthritis Res. Ther.
, vol.9
, Issue.SUPPL. 1
-
-
Boyce, B.F.1
Xing, L.2
-
7
-
-
0032079445
-
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
-
Bucay, N., Sarosi, I., Dunstan, C. R., Morony, S., Tarpley, J., Capparelli, C., Scully, S., Tan, H. L., Xu, W., Lacey, D. L. et al. (1998). osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev. 12, 1260-1268.
-
(1998)
Genes Dev.
, vol.12
, pp. 1260-1268
-
-
Bucay, N.1
Sarosi, I.2
Dunstan, C.R.3
Morony, S.4
Tarpley, J.5
Capparelli, C.6
Scully, S.7
Tan, H.L.8
Xu, W.9
Lacey, D.L.10
-
8
-
-
41149094679
-
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis
-
Canon, J. R., Roudier, M., Bryant, R., Morony, S., Stolina, M., Kostenuik, P. J. and Dougall, W. C. (2008). Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis. Clin. Exp. Metastasis 25, 119-129.
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 119-129
-
-
Canon, J.R.1
Roudier, M.2
Bryant, R.3
Morony, S.4
Stolina, M.5
Kostenuik, P.J.6
Dougall, W.C.7
-
9
-
-
0035861314
-
IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
-
Cao, Y., Bonizzi, G., Seagroves, T. N., Greten, F. R., Johnson, R., Schmidt, E. V. and Karin, M. (2001). IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 107, 763-775.
-
(2001)
Cell
, vol.107
, pp. 763-775
-
-
Cao, Y.1
Bonizzi, G.2
Seagroves, T.N.3
Greten, F.R.4
Johnson, R.5
Schmidt, E.V.6
Karin, M.7
-
10
-
-
79951804629
-
RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation
-
Chen, L.-M., Kuo, C.-H., Lai, T.-Y., Lin, Y.-M., Su, C.-C., Hsu, H.-H., Tsai, F.-J., Tsai, C.-H., Huang, C.-Y. and Tang, C.-H. (2010). RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation. J. Cell. Biochem. 112, 933-941.
-
(2010)
J. Cell. Biochem.
, vol.112
, pp. 933-941
-
-
Chen, L.-M.1
Kuo, C.-H.2
Lai, T.-Y.3
Lin, Y.-M.4
Su, C.-C.5
Hsu, H.-H.6
Tsai, F.-J.7
Tsai, C.-H.8
Huang, C.-Y.9
Tang, C.-H.10
-
11
-
-
27844598284
-
The Akt/PKB pathway: molecular target for cancer drug discovery
-
Cheng, J. Q., Lindsley, C. W., Cheng, G. Z., Yang, H. and Nicosia, S. V. (2005). The Akt/PKB pathway: molecular target for cancer drug discovery. Oncogene 24, 7482-s7492.
-
(2005)
Oncogene
, vol.24
, pp. 7482-7492
-
-
Cheng, J.Q.1
Lindsley, C.W.2
Cheng, G.Z.3
Yang, H.4
Nicosia, S.V.5
-
12
-
-
0033582819
-
Activation of NFkappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif
-
Darnay, B. G., Ni, J., Moore, P. A. and Aggarwal, B. B. (1999). Activation of NFkappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif. J. Biol. Chem. 274, 7724-7731.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7724-7731
-
-
Darnay, B.G.1
Ni, J.2
Moore, P.A.3
Aggarwal, B.B.4
-
13
-
-
0019489816
-
Basal lamina formation by normal and transformed mouse mammary epithelial cells duplicated in vitro
-
David, G., Van der Schueren, B. and Bernfield, M. (1981). Basal lamina formation by normal and transformed mouse mammary epithelial cells duplicated in vitro. J. Natl. Cancer Inst. 67, 719-728.
-
(1981)
J. Natl. Cancer Inst.
, vol.67
, pp. 719-728
-
-
David, G.1
Van der Schueren, B.2
Bernfield, M.3
-
14
-
-
55249106214
-
RANKL signaling in bone physiology and cancer
-
Dougall, W. C. (2007). RANKL signaling in bone physiology and cancer. Curr. Opin. Support. Palliat. Care 1, 317-322.
-
(2007)
Curr. Opin. Support. Palliat. Care
, vol.1
, pp. 317-322
-
-
Dougall, W.C.1
-
15
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
Dougall, W. C., Glaccum, M., Charrier, K., Rohrbach, K., Brasel, K., De Smedt, T., Daro, E., Smith, J., Tometsko, M. E., Maliszewski, C. R. et al. (1999). RANK is essential for osteoclast and lymph node development. Genes Dev. 13, 2412-2424.
-
(1999)
Genes Dev.
, vol.13
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
Rohrbach, K.4
Brasel, K.5
De Smedt, T.6
Daro, E.7
Smith, J.8
Tometsko, M.E.9
Maliszewski, C.R.10
-
16
-
-
79955089567
-
Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit
-
Duheron, V., Hess, E., Duval, M., Decossas, M., Castaneda, B., Klöpper, J. E., Amoasii, L., Barbaroux, J.-B., Williams, I. R., Yagita, H. et al. (2011). Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc. Natl. Acad. Sci. USA 108, 5342-5347.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 5342-5347
-
-
Duheron, V.1
Hess, E.2
Duval, M.3
Decossas, M.4
Castaneda, B.5
Klöpper, J.E.6
Amoasii, L.7
Barbaroux, J.-B.8
Williams, I.R.9
Yagita, H.10
-
17
-
-
0034730327
-
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
-
Fata, J. E., Kong, Y. Y., Li, J., Sasaki, T., Irie-Sasaki, J., Moorehead, R. A., Elliott, R., Scully, S., Voura, E. B., Lacey, D. L. et al. (2000). The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 103, 41-50.
-
(2000)
Cell
, vol.103
, pp. 41-50
-
-
Fata, J.E.1
Kong, Y.Y.2
Li, J.3
Sasaki, T.4
Irie-Sasaki, J.5
Moorehead, R.A.6
Elliott, R.7
Scully, S.8
Voura, E.B.9
Lacey, D.L.10
-
18
-
-
33749252752
-
Mixed metastatic lung cancer lesions in bone are inhibited by noggin overexpression and Rank:Fc administration
-
Feeley, B. T., Liu, N. Q., Conduah, A. H., Krenek, L., Roth, K., Dougall, W. C., Huard, J., Dubinett, S. and Lieberman, J. R. (2006). Mixed metastatic lung cancer lesions in bone are inhibited by noggin overexpression and Rank:Fc administration. J. Bone Miner. Res. 21, 1571-1580.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1571-1580
-
-
Feeley, B.T.1
Liu, N.Q.2
Conduah, A.H.3
Krenek, L.4
Roth, K.5
Dougall, W.C.6
Huard, J.7
Dubinett, S.8
Lieberman, J.R.9
-
19
-
-
61349178831
-
The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse
-
Fernandez-Valdivia, R., Mukherjee, A., Ying, Y., Li, J., Paquet, M., Demayo, F. J. and Lydon, J. P. (2009). The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev. Biol. 328, 127-139.
-
(2009)
Dev. Biol.
, vol.328
, pp. 127-139
-
-
Fernandez-Valdivia, R.1
Mukherjee, A.2
Ying, Y.3
Li, J.4
Paquet, M.5
Demayo, F.J.6
Lydon, J.P.7
-
20
-
-
33846911452
-
RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini
-
Gonzalez-Suarez, E., Branstetter, D., Armstrong, A., Dinh, H., Blumberg, H. and Dougall, W. C. (2007). RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini. Mol. Cell. Biol. 27, 1442-1454.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1442-1454
-
-
Gonzalez-Suarez, E.1
Branstetter, D.2
Armstrong, A.3
Dinh, H.4
Blumberg, H.5
Dougall, W.C.6
-
21
-
-
78149284767
-
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
-
Gonzalez-Suarez, E., Jacob, A. P., Jones, J., Miller, R., Roudier-Meyer, M. P., Erwert, R., Pinkas, J., Branstetter, D. and Dougall, W. C. (2010). RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature 468, 103-107.
-
(2010)
Nature
, vol.468
, pp. 103-107
-
-
Gonzalez-Suarez, E.1
Jacob, A.P.2
Jones, J.3
Miller, R.4
Roudier-Meyer, M.P.5
Erwert, R.6
Pinkas, J.7
Branstetter, D.8
Dougall, W.C.9
-
22
-
-
77957165721
-
Involvement of integrin up-regulation in RANKL/RANK pathway of chondrosarcomas migration
-
Hsu, C.-J., Lin, T.-Y., Kuo, C.-C., Tsai, C.-H., Lin, M.-Z., Hsu, H.-C., Fong, Y.-C. and Tang, C.-H. (2010). Involvement of integrin up-regulation in RANKL/RANK pathway of chondrosarcomas migration. J. Cell. Biochem. 111, 138-147.
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 138-147
-
-
Hsu, C.-J.1
Lin, T.-Y.2
Kuo, C.-C.3
Tsai, C.-H.4
Lin, M.-Z.5
Hsu, H.-C.6
Fong, Y.-C.7
Tang, C.-H.8
-
23
-
-
33645453481
-
Regulation of cancer cell migration and bone metastasis by RANKL
-
Jones, D. H., Nakashima, T., Sanchez, O. H., Kozieradzki, I., Komarova, S. V., Sarosi, I., Morony, S., Rubin, E., Sarao, R., Hojilla, C. V. et al. (2006). Regulation of cancer cell migration and bone metastasis by RANKL. Nature 440, 692-696.
-
(2006)
Nature
, vol.440
, pp. 692-696
-
-
Jones, D.H.1
Nakashima, T.2
Sanchez, O.H.3
Kozieradzki, I.4
Komarova, S.V.5
Sarosi, I.6
Morony, S.7
Rubin, E.8
Sarao, R.9
Hojilla, C.V.10
-
24
-
-
77953388315
-
Progesterone induces adult mammary stem cell expansion
-
Joshi, P. A., Jackson, H. W., Beristain, A. G., Di Grappa, M. A., Mote, P., Clarke, C., Stingl, J., Waterhouse, P. D. and Khokha, R. (2010). Progesterone induces adult mammary stem cell expansion. Nature 465, 803-807.
-
(2010)
Nature
, vol.465
, pp. 803-807
-
-
Joshi, P.A.1
Jackson, H.W.2
Beristain, A.G.3
Di Grappa, M.A.4
Mote, P.5
Clarke, C.6
Stingl, J.7
Waterhouse, P.D.8
Khokha, R.9
-
25
-
-
0034852195
-
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
-
Kim, D., Kim, S., Koh, H., Yoon, S. O., Chung, A. S., Cho, K. S. and Chung, J. (2001). Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB J. 15, 1953-1962.
-
(2001)
FASEB J.
, vol.15
, pp. 1953-1962
-
-
Kim, D.1
Kim, S.2
Koh, H.3
Yoon, S.O.4
Chung, A.S.5
Cho, K.S.6
Chung, J.7
-
26
-
-
31344455071
-
Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2
-
Kim, N. S., Kim, H. J., Koo, B. K., Kwon, M. C., Kim, Y. W., Cho, Y., Yokota, Y., Penninger, J. M. and Kong, Y. Y. (2006). Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2. Mol. Cell. Biol. 26, 1002-1013.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1002-1013
-
-
Kim, N.S.1
Kim, H.J.2
Koo, B.K.3
Kwon, M.C.4
Kim, Y.W.5
Cho, Y.6
Yokota, Y.7
Penninger, J.M.8
Kong, Y.Y.9
-
27
-
-
0036773564
-
RANK ligand is a prerequisite for cancerassociated osteolytic lesions
-
Kitazawa, S. and Kitazawa, R. (2002). RANK ligand is a prerequisite for cancerassociated osteolytic lesions. J. Pathol. 198, 228-236.
-
(2002)
J. Pathol.
, vol.198
, pp. 228-236
-
-
Kitazawa, S.1
Kitazawa, R.2
-
28
-
-
0035868884
-
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
-
Kobayashi, N., Kadono, Y., Naito, A., Matsumoto, K., Yamamoto, T., Tanaka, S. and Inoue, J. (2001). Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J. 20, 1271-1280.
-
(2001)
EMBO J.
, vol.20
, pp. 1271-1280
-
-
Kobayashi, N.1
Kadono, Y.2
Naito, A.3
Matsumoto, K.4
Yamamoto, T.5
Tanaka, S.6
Inoue, J.7
-
29
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong, Y. Y., Yoshida, H., Sarosi, I., Tan, H. L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A. et al. (1999). OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397, 315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
Morony, S.7
Oliveira-dos-Santos, A.J.8
Van, G.9
Itie, A.10
-
30
-
-
17444452820
-
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients
-
Kotake, S., Udagawa, N., Hakoda, M., Mogi, M., Yano, K., Tsuda, E., Takahashi, K., Furuya, T., Ishiyama, S., Kim, K. J. et al. (2001). Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum. 44, 1003-1012.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 1003-1012
-
-
Kotake, S.1
Udagawa, N.2
Hakoda, M.3
Mogi, M.4
Yano, K.5
Tsuda, E.6
Takahashi, K.7
Furuya, T.8
Ishiyama, S.9
Kim, K.J.10
-
31
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey, D. L., Timms, E., Tan, H. L., Kelley, M. J., Dunstan, C. R., Burgess, T., Elliott, R., Colombero, A., Elliott, G., Scully, S. et al. (1998). Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93, 165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
-
32
-
-
34250668795
-
TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation
-
Lamothe, B., Webster, W. K., Gopinathan, A., Besse, A., Campos, A. D. and Darnay, B. G. (2007). TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation. Biochem. Biophys. Res. Commun. 359, 1044-1049.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, pp. 1044-1049
-
-
Lamothe, B.1
Webster, W.K.2
Gopinathan, A.3
Besse, A.4
Campos, A.D.5
Darnay, B.G.6
-
33
-
-
34547629223
-
Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption
-
Lamoureux, F., Richard, P., Wittrant, Y., Battaglia, S., Pilet, P., Trichet, V., Blanchard, F., Gouin, F., Pitard, B., Heymann, D. et al. (2007). Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption. Cancer Res. 67, 7308-7318.
-
(2007)
Cancer Res.
, vol.67
, pp. 7308-7318
-
-
Lamoureux, F.1
Richard, P.2
Wittrant, Y.3
Battaglia, S.4
Pilet, P.5
Trichet, V.6
Blanchard, F.7
Gouin, F.8
Pitard, B.9
Heymann, D.10
-
34
-
-
40449083107
-
RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells
-
Lee, H. W., Park, H. K., Na, Y. J., Kim, C. D., Lee, J. H., Kim, B. S., Kim, J. B., Lee, C. W., Moon, J. O. and Yoon, S. (2008). RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells. Exp. Mol. Med. 40, 59-70.
-
(2008)
Exp. Mol. Med.
, vol.40
, pp. 59-70
-
-
Lee, H.W.1
Park, H.K.2
Na, Y.J.3
Kim, C.D.4
Lee, J.H.5
Kim, B.S.6
Kim, J.B.7
Lee, C.W.8
Moon, J.O.9
Yoon, S.10
-
35
-
-
79952131163
-
RANKL expression is related to treatment outcome of patients with localized, high-grade osteosarcoma
-
Lee, J. A., Jung, J. S., Kim, D. H., Lim, J. S., Kim, M. S., Kong, C. B., Song, W. S., Cho, W. H., Jeon, D. G., Lee, S. Y. et al. (2011). RANKL expression is related to treatment outcome of patients with localized, high-grade osteosarcoma. Pediatr. Blood Cancer 56, 738-743.
-
(2011)
Pediatr. Blood Cancer
, vol.56
, pp. 738-743
-
-
Lee, J.A.1
Jung, J.S.2
Kim, D.H.3
Lim, J.S.4
Kim, M.S.5
Kong, C.B.6
Song, W.S.7
Cho, W.H.8
Jeon, D.G.9
Lee, S.Y.10
-
36
-
-
56549098575
-
RANK/RANKL: regulators of immune responses and bone physiology
-
Leibbrandt, A. and Penninger, J. M. (2008). RANK/RANKL: regulators of immune responses and bone physiology. Ann. N. Y. Acad. Sci. 1143, 123-150.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1143
, pp. 123-150
-
-
Leibbrandt, A.1
Penninger, J.M.2
-
37
-
-
0033532191
-
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival
-
Lum, L., Wong, B. R., Josien, R., Becherer, J. D., Erdjument-Bromage, H., Schlöndorff, J., Tempst, P., Choi, Y. and Blobel, C. P. (1999). Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. J. Biol. Chem. 274, 13613-13618.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13613-13618
-
-
Lum, L.1
Wong, B.R.2
Josien, R.3
Becherer, J.D.4
Erdjument-Bromage, H.5
Schlondorff, J.6
Tempst, P.7
Choi, Y.8
Blobel, C.P.9
-
38
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
Meloche, S. and Pouysségur, J. (2007). The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 26, 3227-3239.
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouysségur, J.2
-
39
-
-
51049121618
-
RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis
-
Miller, R. E., Roudier, M., Jones, J., Armstrong, A., Canon, J. and Dougall, W. C. (2008). RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. Mol. Cancer Ther. 7, 2160-2169.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2160-2169
-
-
Miller, R.E.1
Roudier, M.2
Jones, J.3
Armstrong, A.4
Canon, J.5
Dougall, W.C.6
-
40
-
-
77956368069
-
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
-
Molyneux, S. D., Di Grappa, M. A., Beristain, A. G., McKee, T. D., Wai, D. H., Paderova, J., Kashyap, M., Hu, P., Maiuri, T., Narala, S. R. et al. (2010). Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. J. Clin. Invest. 120, 310-3325.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 310-3325
-
-
Molyneux, S.D.1
Di Grappa, M.A.2
Beristain, A.G.3
McKee, T.D.4
Wai, D.H.5
Paderova, J.6
Kashyap, M.7
Hu, P.8
Maiuri, T.9
Narala, S.R.10
-
41
-
-
33947646303
-
Human osteosarcoma cells express functional receptor activator of nuclear factor-kappa B
-
Mori, K., Le Goff, B., Berreur, M., Riet, A., Moreau, A., Blanchard, F., Chevalier, C., Guisle-Marsollier, I., Léger, J., Guicheux, J. et al. (2007). Human osteosarcoma cells express functional receptor activator of nuclear factor-kappa B. J. Pathol. 211, 555-562.
-
(2007)
J. Pathol.
, vol.211
, pp. 555-562
-
-
Mori, K.1
Le Goff, B.2
Berreur, M.3
Riet, A.4
Moreau, A.5
Blanchard, F.6
Chevalier, C.7
Guisle-Marsollier, I.8
Léger, J.9
Guicheux, J.10
-
42
-
-
0035360265
-
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis
-
Morony, S., Capparelli, C., Sarosi, I., Lacey, D. L., Dunstan, C. R. and Kostenuik, P. J. (2001). Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis. Cancer Res. 61, 4432-4436.
-
(2001)
Cancer Res.
, pp. 4432-4436
-
-
Morony, S.1
Capparelli, C.2
Sarosi, I.3
Lacey, D.L.4
Dunstan, C.R.5
Kostenuik, P.J.6
-
43
-
-
4043110719
-
Induction of RANKL expression and osteoclast maturation by the binding of fibroblast growth factor 2 to heparan sulfate proteoglycan on rheumatoid synovial fibroblasts
-
Nakano, K., Okada, Y., Saito, K. and Tanaka, Y. (2004). Induction of RANKL expression and osteoclast maturation by the binding of fibroblast growth factor 2 to heparan sulfate proteoglycan on rheumatoid synovial fibroblasts. Arthritis Rheum. 50, 2450-2458.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2450-2458
-
-
Nakano, K.1
Okada, Y.2
Saito, K.3
Tanaka, Y.4
-
44
-
-
77954355093
-
Shedding of RANKL by tumor-associated MT1-MMP activates Srcdependent prostate cancer cell migration
-
Sabbota, A. L., Kim, H.-R. C., Zhe, X., Fridman, R., Bonfil, R. D. and Cher, M. L. (2010). Shedding of RANKL by tumor-associated MT1-MMP activates Srcdependent prostate cancer cell migration. Cancer Res. 70, 5558-5566.
-
(2010)
Cancer Res.
, vol.70
, pp. 5558-5566
-
-
Sabbota, A.L.1
Kim, H.-R.C.2
Zhe, X.3
Fridman, R.4
Bonfil, R.D.5
Cher, M.L.6
-
45
-
-
79955772442
-
Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients
-
Santini, D., Schiavon, G., Vincenzi, B., Gaeta, L., Pantano, F., Russo, A., Ortega, C., Porta, C., Galluzzo, S., Armento, G. et al. (2011). Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients. PLoS ONE 6, e19234.
-
(2011)
PLoS ONE
, vol.6
-
-
Santini, D.1
Schiavon, G.2
Vincenzi, B.3
Gaeta, L.4
Pantano, F.5
Russo, A.6
Ortega, C.7
Porta, C.8
Galluzzo, S.9
Armento, G.10
-
46
-
-
1342322686
-
Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion
-
Schäfer, B., Gschwind, A. and Ullrich, A. (2004). Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion. Oncogene 23, 991-999.
-
(2004)
Oncogene
, vol.23
, pp. 991-999
-
-
Schäfer, B.1
Gschwind, A.2
Ullrich, A.3
-
47
-
-
0037862006
-
Unravelling the activation mechanisms of protein kinase B/Akt
-
Scheid, M. P. and Woodgett, J. R. (2003). Unravelling the activation mechanisms of protein kinase B/Akt. FEBS Lett. 546, 108-112.
-
(2003)
FEBS Lett.
, vol.546
, pp. 108-112
-
-
Scheid, M.P.1
Woodgett, J.R.2
-
48
-
-
78149284013
-
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
-
Schramek, D., Leibbrandt, A., Sigl, V., Kenner, L., Pospisilik, J. A., Lee, H. J., Hanada, R., Joshi, P. A., Aliprantis, A., Glimcher, L. et al. (2010). Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 468, 98-102.
-
(2010)
Nature
, vol.468
, pp. 98-102
-
-
Schramek, D.1
Leibbrandt, A.2
Sigl, V.3
Kenner, L.4
Pospisilik, J.A.5
Lee, H.J.6
Hanada, R.7
Joshi, P.A.8
Aliprantis, A.9
Glimcher, L.10
-
49
-
-
0028919917
-
Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells
-
Soriano, J. V., Pepper, M. S., Nakamura, T., Orci, L. and Montesano, R. (1995). Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. J. Cell Sci. 108, 413-430.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 413-430
-
-
Soriano, J.V.1
Pepper, M.S.2
Nakamura, T.3
Orci, L.4
Montesano, R.5
-
50
-
-
79952193038
-
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
-
Tan, W., Zhang, W., Strasner, A., Grivennikov, S., Cheng, J. Q., Hoffman, R. M. and Karin, M. (2011). Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature 470, 548-553.
-
(2011)
Nature
, vol.470
, pp. 548-553
-
-
Tan, W.1
Zhang, W.2
Strasner, A.3
Grivennikov, S.4
Cheng, J.Q.5
Hoffman, R.M.6
Karin, M.7
-
52
-
-
70349732865
-
Adhesion-mediated apoptosis resistance in cancer
-
Westhoff, M.-A. and Fulda, S. (2009). Adhesion-mediated apoptosis resistance in cancer. Drug Resist. Updat. 12, 27-136.
-
(2009)
Drug Resist. Updat.
, vol.12
, pp. 27-136
-
-
Westhoff, M.-A.1
Fulda, S.2
-
53
-
-
33644793514
-
RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells
-
Wittrant, Y., Lamoureux, F., Mori, K., Riet, A., Kamijo, A., Heymann, D. and Redini, F. (2006). RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells. Int. J. Oncol. 28, 261-269.
-
(2006)
Int. J. Oncol.
, vol.28
, pp. 261-269
-
-
Wittrant, Y.1
Lamoureux, F.2
Mori, K.3
Riet, A.4
Kamijo, A.5
Heymann, D.6
Redini, F.7
-
54
-
-
14444272043
-
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
-
Wong, B. R., Rho, J., Arron, J., Robinson, E., Orlinick, J., Chao, M., Kalachikov, S., Cayani, E., Bartlett, F. S., Frankel, W. N. et al. (1997). TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 272, 25190-25194.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25190-25194
-
-
Wong, B.R.1
Rho, J.2
Arron, J.3
Robinson, E.4
Orlinick, J.5
Chao, M.6
Kalachikov, S.7
Cayani, E.8
Bartlett, F.S.9
Frankel, W.N.10
-
55
-
-
0032561198
-
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor
-
Wong, B. R., Josien, R., Lee, S. Y., Vologodskaia, M., Steinman, R. M. and Choi, Y. (1998). The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor. J. Biol. Chem. 273, 28355-28359.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28355-28359
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
Vologodskaia, M.4
Steinman, R.M.5
Choi, Y.6
-
56
-
-
0033393957
-
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src
-
Wong, B. R., Besser, D., Kim, N., Arron, J. R., Vologodskaia, M., Hanafusa, H. and Choi, Y. (1999). TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol. Cell 4,1041-1049.
-
(1999)
Mol. Cell
, vol.4
, pp. 1041-1049
-
-
Wong, B.R.1
Besser, D.2
Kim, N.3
Arron, J.R.4
Vologodskaia, M.5
Hanafusa, H.6
Choi, Y.7
-
57
-
-
0035862994
-
Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival
-
Xing, L., Venegas, A. M., Chen, A., Garrett-Beal, L., Boyce, B. F., Varmus, H. E. and Schwartzberg, P. L. (2001). Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. Genes Dev. 15, 241-253.
-
(2001)
Genes Dev.
, vol.15
, pp. 241-253
-
-
Xing, L.1
Venegas, A.M.2
Chen, A.3
Garrett-Beal, L.4
Boyce, B.F.5
Varmus, H.E.6
Schwartzberg, P.L.7
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