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Volumn 15, Issue 4, 2009, Pages 417-424

Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; ESTROGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

EID: 64449083350     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1945     Document Type: Article
Times cited : (163)

References (44)
  • 1
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum, S.L. Bone resorption by osteoclasts. Science 289, 1504-1508 (2000).
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 2
    • 33646396235 scopus 로고    scopus 로고
    • Estrogen deficiency and bone loss: An inflammatory tale
    • Weitzmann, M.N. & Pacifici, R. Estrogen deficiency and bone loss: an inflammatory tale. J. Clin. Invest. 116, 1186-1194 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 1186-1194
    • Weitzmann, M.N.1    Pacifici, R.2
  • 3
    • 0037362364 scopus 로고    scopus 로고
    • Differentiation and function of osteoclasts
    • Miyamoto, T. & Suda, T. Differentiation and function of osteoclasts. Keio J. Med. 52, 1-7 (2003).
    • (2003) Keio J. Med , vol.52 , pp. 1-7
    • Miyamoto, T.1    Suda, T.2
  • 4
    • 0842327417 scopus 로고    scopus 로고
    • Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis
    • Stepan, J.J., Alenfeld, F., Boivin, G., Feyen, J.H. & Lakatos, P. Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis. Endocr. Regul. 37, 225-238 (2003).
    • (2003) Endocr. Regul , vol.37 , pp. 225-238
    • Stepan, J.J.1    Alenfeld, F.2    Boivin, G.3    Feyen, J.H.4    Lakatos, P.5
  • 6
    • 0342322717 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 1-α is a potential osteoclast stimulatory factor in multiple myeloma
    • Choi, S.J. et al. Macrophage inflammatory protein 1-α is a potential osteoclast stimulatory factor in multiple myeloma. Blood 96, 671-675 (2000).
    • (2000) Blood , vol.96 , pp. 671-675
    • Choi, S.J.1
  • 7
    • 18144393375 scopus 로고    scopus 로고
    • MCP-1 is induced by receptor activator of nuclear factor-κB ligand, promotes human osteoclast fusion and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation
    • Kim, M.S., Day, C.J. & Morrison, N.A. MCP-1 is induced by receptor activator of nuclear factor-κB ligand, promotes human osteoclast fusion and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation. J. Biol. Chem. 280, 16163-16169 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 16163-16169
    • Kim, M.S.1    Day, C.J.2    Morrison, N.A.3
  • 8
    • 33644854945 scopus 로고    scopus 로고
    • MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkB ligand for bone resorption
    • Kim, M.S. et al. MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkB ligand for bone resorption. J. Biol. Chem. 281, 1274-1285 (2006).
    • (2006) J. Biol. Chem , vol.281 , pp. 1274-1285
    • Kim, M.S.1
  • 10
    • 0030809822 scopus 로고    scopus 로고
    • Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
    • Boring, L. et al. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J. Clin. Invest. 100, 2552-2561 (1997).
    • (1997) J. Clin. Invest , vol.100 , pp. 2552-2561
    • Boring, L.1
  • 11
    • 0028316908 scopus 로고
    • Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxylterminal tails
    • Charo, I.F. et al. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxylterminal tails. Proc. Natl. Acad. Sci. USA 91, 2752-2756 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2752-2756
    • Charo, I.F.1
  • 12
    • 45549091996 scopus 로고    scopus 로고
    • Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection
    • Jia, T. et al. Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection. J. Immunol. 180, 6846-6853 (2008).
    • (2008) J. Immunol , vol.180 , pp. 6846-6853
    • Jia, T.1
  • 13
    • 33144460421 scopus 로고    scopus 로고
    • Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES
    • Kim, M.S., Magno, C.L., Day, C.J. & Morrison, N.A. Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES. J. Cell. Biochem. 97, 512-518 (2006).
    • (2006) J. Cell. Biochem , vol.97 , pp. 512-518
    • Kim, M.S.1    Magno, C.L.2    Day, C.J.3    Morrison, N.A.4
  • 14
    • 0022622964 scopus 로고
    • Evaluation of serum osteocalcin as an index of altered bone metabolism
    • Kruse, K. & Kracht, U. Evaluation of serum osteocalcin as an index of altered bone metabolism. Eur. J. Pediatr. 145, 27-33 (1986).
    • (1986) Eur. J. Pediatr , vol.145 , pp. 27-33
    • Kruse, K.1    Kracht, U.2
  • 15
    • 0019746048 scopus 로고
    • Biochemical markers of bone turnover in Paget's disease
    • Russell, R.G. et al. Biochemical markers of bone turnover in Paget's disease. Metab. Bone Dis. Relat. Res. 3, 255-262 (1981).
    • (1981) Metab. Bone Dis. Relat. Res , vol.3 , pp. 255-262
    • Russell, R.G.1
  • 16
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey, D.L. et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93, 165-176 (1998).
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1
  • 17
    • 0347719264 scopus 로고    scopus 로고
    • Systemic tumor necrosis factor a mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor α-transgenic mice
    • Li, P. et al. Systemic tumor necrosis factor a mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor α-transgenic mice. Arthritis Rheum. 50, 265-276 (2004).
    • (2004) Arthritis Rheum , vol.50 , pp. 265-276
    • Li, P.1
  • 18
    • 34147164049 scopus 로고    scopus 로고
    • Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
    • Tsou, CL. et al. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 117, 902-909 (2007).
    • (2007) J. Clin. Invest , vol.117 , pp. 902-909
    • Tsou, C.L.1
  • 19
    • 0036075148 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 induces proliferation and inter-leukin-6 production in human smooth muscle cells by differential activation of nuclear factor-κB and activator protein-1
    • Viedt, C. et al. Monocyte chemoattractant protein-1 induces proliferation and inter-leukin-6 production in human smooth muscle cells by differential activation of nuclear factor-κB and activator protein-1. Arterioscler. Thromb. Vasc. Biol. 22, 914-920 (2002).
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 914-920
    • Viedt, C.1
  • 20
    • 22544439953 scopus 로고    scopus 로고
    • Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
    • Idris, A.I. et al. Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors. Nat. Med. 11, 774-779 (2005).
    • (2005) Nat. Med , vol.11 , pp. 774-779
    • Idris, A.I.1
  • 21
    • 0023930991 scopus 로고
    • Tamoxifen inhibits osteoclastmediated resorption of trabecular bone in ovarian hormone-deficient rats
    • Turner, R.T., Wakley, G.K., Hannon, K.S. & Bell, N.H. Tamoxifen inhibits osteoclastmediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology 122, 1146-1150 (1988).
    • (1988) Endocrinology , vol.122 , pp. 1146-1150
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 22
    • 27744499202 scopus 로고    scopus 로고
    • The expression of CCL2 byT lymphocytes of mammary tumor bearers: Role of tumor-derived factors
    • Owen, J.L. et al. The expression of CCL2 byT lymphocytes of mammary tumor bearers: role of tumor-derived factors. Cell. Immunol. 235, 122-135 (2005).
    • (2005) Cell. Immunol , vol.235 , pp. 122-135
    • Owen, J.L.1
  • 23
    • 33744777162 scopus 로고    scopus 로고
    • Direct and indirect estrogen actions on osteoblasts and osteoclasts
    • Zallone, A. Direct and indirect estrogen actions on osteoblasts and osteoclasts. Ann. N.Y. Acad. Sci. 1068, 173-179 (2006).
    • (2006) Ann. N.Y. Acad. Sci , vol.1068 , pp. 173-179
    • Zallone, A.1
  • 24
    • 0026641955 scopus 로고
    • Cytokines, hematopoiesis, osteoclastogenesis and estrogens
    • Manolagas, S.C. & Jilka, R.L. Cytokines, hematopoiesis, osteoclastogenesis and estrogens. Calcif. Tissue Int. 50, 199-202 (1992).
    • (1992) Calcif. Tissue Int , vol.50 , pp. 199-202
    • Manolagas, S.C.1    Jilka, R.L.2
  • 26
    • 0029166052 scopus 로고
    • Role of cytokines in bone resorption
    • Manolagas, S.C. Role of cytokines in bone resorption. Bone 17, 63S-67S (1995).
    • (1995) Bone , vol.17
    • Manolagas, S.C.1
  • 27
    • 0033708837 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T cell production of TNF-α
    • Cenci, S. etal. Estrogen deficiency induces bone loss by enhancing T cell production of TNF-α. J. Clin. Invest. 106, 1229-1237 (2000).
    • (2000) J. Clin. Invest , vol.106 , pp. 1229-1237
    • Cenci, S.1
  • 28
    • 14944371405 scopus 로고    scopus 로고
    • Wei, S., Kitaura, H., Zhou, P., Ross, F.P. & Teitelbaum, S.L. IL-1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest. 115, 282-290 (2005).
    • Wei, S., Kitaura, H., Zhou, P., Ross, F.P. & Teitelbaum, S.L. IL-1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest. 115, 282-290 (2005).
  • 29
    • 0036035369 scopus 로고    scopus 로고
    • CCL9/MIP-1γ and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts
    • Lean, J.M., Murphy, C, Fuller, K. & Chambers, T.J. CCL9/MIP-1γ and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts. J. Cell. Biochem. 87, 386-393 (2002).
    • (2002) J. Cell. Biochem , vol.87 , pp. 386-393
    • Lean, J.M.1    Murphy, C.2    Fuller, K.3    Chambers, T.J.4
  • 30
    • 34548559114 scopus 로고    scopus 로고
    • Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma
    • Breitkreutz, I. et al. Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br. J. Haematol. 139, 55-63 (2007).
    • (2007) Br. J. Haematol , vol.139 , pp. 55-63
    • Breitkreutz, I.1
  • 31
    • 0442325394 scopus 로고    scopus 로고
    • Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytes
    • Janis, K. et al. Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytes. Am. J. Reprod. Immunol. 51, 22-31 (2004).
    • (2004) Am. J. Reprod. Immunol , vol.51 , pp. 22-31
    • Janis, K.1
  • 32
    • 0033057004 scopus 로고    scopus 로고
    • Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by estrogen and progesterone
    • Arici, A., Senturk, L.M., Seli, E., Bahtiyar, M.O. & Kim, G. Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by estrogen and progesterone. Biol. Reprod. 61, 85-90 (1999).
    • (1999) Biol. Reprod , vol.61 , pp. 85-90
    • Arici, A.1    Senturk, L.M.2    Seli, E.3    Bahtiyar, M.O.4    Kim, G.5
  • 33
    • 0034749552 scopus 로고    scopus 로고
    • Effect of hormone replacement therapy on nitric oxide bioactivity and monocyte chemoattractant protein-1 levels
    • Koh, K.K. et al. Effect of hormone replacement therapy on nitric oxide bioactivity and monocyte chemoattractant protein-1 levels. Int. J. Cardiol. 81, 43-50 (2001).
    • (2001) Int. J. Cardiol , vol.81 , pp. 43-50
    • Koh, K.K.1
  • 34
    • 33344469853 scopus 로고    scopus 로고
    • Denosumab in postmenopausal women with low bone mineral density
    • McClung, M.R. et al. Denosumab in postmenopausal women with low bone mineral density. N. Engl. J. Med. 354, 821-831 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 821-831
    • McClung, M.R.1
  • 35
    • 0033568341 scopus 로고    scopus 로고
    • RANK is essential for osteoclast and lymph node development
    • Dougall, W.C et al. RANK is essential for osteoclast and lymph node development. Genes Dev. 13, 2412-2424 (1999).
    • (1999) Genes Dev , vol.13 , pp. 2412-2424
    • Dougall, W.C.1
  • 36
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong, Y.Y. et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397, 315-323 (1999).
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1
  • 37
    • 0036287198 scopus 로고    scopus 로고
    • Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral density
    • Yamada, Y, Ando, F, Niino, N. & Shimokata, H. Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral density. Genomics 80, 8-12 (2002).
    • (2002) Genomics , vol.80 , pp. 8-12
    • Yamada, Y.1    Ando, F.2    Niino, N.3    Shimokata, H.4
  • 38
    • 20244385583 scopus 로고    scopus 로고
    • CD44 is a determinant of inflammatory bone loss
    • Hayer, S. et al. CD44 is a determinant of inflammatory bone loss. J. Exp. Med. 201, 903-914 (2005).
    • (2005) J. Exp. Med , vol.201 , pp. 903-914
    • Hayer, S.1
  • 39
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt, A.M. et al. Bone histomorphometry: standardization of nomenclature, symbols and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2, 595-610 (1987).
    • (1987) J. Bone Miner. Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1
  • 40
    • 0033940801 scopus 로고    scopus 로고
    • Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts
    • Takeshita, S., Kaji, K. & Kudo, A. Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. J. Bone Miner. Res. 15, 1477-1488 (2000).
    • (2000) J. Bone Miner. Res , vol.15 , pp. 1477-1488
    • Takeshita, S.1    Kaji, K.2    Kudo, A.3
  • 41
    • 0036732410 scopus 로고    scopus 로고
    • SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
    • Takeshita, S. et al. SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts. Nat. Med. 8, 943-949 (2002).
    • (2002) Nat. Med , vol.8 , pp. 943-949
    • Takeshita, S.1
  • 42
    • 0033057045 scopus 로고    scopus 로고
    • A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population
    • Herault, O. et al. A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population. Br. J. Haematol. 104, 530-537 (1999).
    • (1999) Br. J. Haematol , vol.104 , pp. 530-537
    • Herault, O.1
  • 43
    • 12144289393 scopus 로고    scopus 로고
    • Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis
    • Redlich, K. et al. Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis. Am. J. Pathol. 164, 543-555 (2004).
    • (2004) Am. J. Pathol , vol.164 , pp. 543-555
    • Redlich, K.1
  • 44
    • 0035313220 scopus 로고    scopus 로고
    • Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice
    • Mack, M. et al. Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J. Immunol. 166, 4697-4704 (2001).
    • (2001) J. Immunol , vol.166 , pp. 4697-4704
    • Mack, M.1


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