메뉴 건너뛰기




Volumn 23, Issue 4, 2000, Pages 175-180

A new concept in neurodegeneration: TNFα is a silencer of survival signals

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN C RECEPTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0034176591     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(99)01533-7     Document Type: Review
Times cited : (181)

References (57)
  • 1
    • 0033578426 scopus 로고    scopus 로고
    • A new mechanism of neurodegeneration: A proinflammatory cytokine inhibits receptor signaling by a survival peptide
    • Venters, H.D. et al. (1999) A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide. Proc. Natl. Acad. Sci. U. S. A. 96, 9879-9884
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 9879-9884
    • Venters, H.D.1
  • 2
    • 0027197996 scopus 로고
    • Neuroprotective role of IL-4 against activated microglia
    • Chao, C.C. et al. (1993) Neuroprotective role of IL-4 against activated microglia. J. Immunol. 151, 1473-1481
    • (1993) J. Immunol. , vol.151 , pp. 1473-1481
    • Chao, C.C.1
  • 3
    • 0345346384 scopus 로고    scopus 로고
    • Adenosine: A mediator of interleukin-1β-induced hippocampal synaptic inhibition
    • Luk, W.P. et al. (1999) Adenosine: a mediator of interleukin-1β-induced hippocampal synaptic inhibition. J. Neurosci. 19, 4238-4244
    • (1999) J. Neurosci. , vol.19 , pp. 4238-4244
    • Luk, W.P.1
  • 4
    • 0033057788 scopus 로고    scopus 로고
    • The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1β on long-term potentiation in the rat dendate gyrus in vitro
    • Coogan, A.N. et al. (1999) The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1β on long-term potentiation in the rat dendate gyrus in vitro. Neuroscience 93, 57-69
    • (1999) Neuroscience , vol.93 , pp. 57-69
    • Coogan, A.N.1
  • 5
    • 0026512096 scopus 로고
    • Sickness behavior as a new target for drug development
    • Kent, S. et al. (1992) Sickness behavior as a new target for drug development. Trends Pharmacol. Sci. 13, 24-28
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 24-28
    • Kent, S.1
  • 6
    • 0033600277 scopus 로고    scopus 로고
    • The changing landscape of ischaemic brain injury mechanisms
    • Lee, J.M. et al. (1999) The changing landscape of ischaemic brain injury mechanisms. Nature 399, A7-A14
    • (1999) Nature , vol.399
    • Lee, J.M.1
  • 7
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz, M. et al. (1999) Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci. 22, 295-299
    • (1999) Trends Neurosci. , vol.22 , pp. 295-299
    • Schwartz, M.1
  • 8
    • 0028800715 scopus 로고
    • Cytokines and the nervous system. I: Expression and recognition
    • Hopkins, S.J. and Rothwell, N.J. (1995) Cytokines and the nervous system. I: expression and recognition. Trends Neurosci. 18, 83-88
    • (1995) Trends Neurosci. , vol.18 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 9
    • 14444276732 scopus 로고    scopus 로고
    • Platelet-activating factor receptor activation: An initiator step in HIV-1 neuropathogenesis
    • Perry, S.W. et al. (1998) Platelet-activating factor receptor activation: An initiator step in HIV-1 neuropathogenesis. J. Biol. Chem. 273, 17660-17664
    • (1998) J. Biol. Chem. , vol.273 , pp. 17660-17664
    • Perry, S.W.1
  • 10
    • 0033103686 scopus 로고    scopus 로고
    • Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment
    • Knoblach, S.M. et al. (1999) Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment. J. Neuroimmunol. 95, 115-125
    • (1999) J. Neuroimmunol. , vol.95 , pp. 115-125
    • Knoblach, S.M.1
  • 11
    • 0031470830 scopus 로고    scopus 로고
    • Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia
    • Botchkina, G.I. et al. (1997) Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia. Mol. Med. 3, 765-781
    • (1997) Mol. Med. , vol.3 , pp. 765-781
    • Botchkina, G.I.1
  • 12
    • 0030976856 scopus 로고    scopus 로고
    • Tumor necrosis factor-α. A mediator of focal ischemic brain injury
    • Barone, F.C. et al. (1997) Tumor necrosis factor-α. A mediator of focal ischemic brain injury. Stroke 28, 1233-1244
    • (1997) Stroke , vol.28 , pp. 1233-1244
    • Barone, F.C.1
  • 13
    • 0031578934 scopus 로고    scopus 로고
    • Neuroprotective effects of TNF binding protein in focal cerebral ischemia
    • Nawashiro, H. et al. (1997) Neuroprotective effects of TNF binding protein in focal cerebral ischemia. Brain Res. 778, 265-271
    • (1997) Brain Res. , vol.778 , pp. 265-271
    • Nawashiro, H.1
  • 14
    • 0032504151 scopus 로고    scopus 로고
    • HIV-1 Tat induces neuronal death via tumor necrosis factor-α and activation of non-N-methyl-D-aspartate receptors by a NFκB-independent mechanism
    • New, D.R. et al. (1998) HIV-1 Tat induces neuronal death via tumor necrosis factor-α and activation of non-N-methyl-D-aspartate receptors by a NFκB-independent mechanism. J. Biol. Chem. 273, 17852-17858
    • (1998) J. Biol. Chem. , vol.273 , pp. 17852-17858
    • New, D.R.1
  • 15
    • 0028178798 scopus 로고
    • Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
    • Cheng, B. et al. (1994) Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 12, 139-153
    • (1994) Neuron , vol.12 , pp. 139-153
    • Cheng, B.1
  • 16
    • 0030941769 scopus 로고    scopus 로고
    • Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism
    • Courtney, M.J. et al. (1997) Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism. J. Neurosci. 17, 4201-4211
    • (1997) J. Neurosci. , vol.17 , pp. 4201-4211
    • Courtney, M.J.1
  • 17
    • 0032524150 scopus 로고    scopus 로고
    • The intracellular domain of p55 tumor necrosis factor receptor induces apoptosis which requires different caspases in naive and neuronal large PC12 cells
    • Haviv, R. and Stein, R. (1998) The intracellular domain of p55 tumor necrosis factor receptor induces apoptosis which requires different caspases in naive and neuronal large PC12 cells. J. Neurosci. Res. 52, 380-389
    • (1998) J. Neurosci. Res. , vol.52 , pp. 380-389
    • Haviv, R.1    Stein, R.2
  • 18
    • 0029974268 scopus 로고    scopus 로고
    • An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line
    • Sipe, K.J. et al. (1996) An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line. Mol. Brain. Res. 38, 222-232
    • (1996) Mol. Brain. Res. , vol.38 , pp. 222-232
    • Sipe, K.J.1
  • 19
    • 0031798012 scopus 로고    scopus 로고
    • Ischemic and excitoxic brain injury is enhanced in mice lacking the small p55 tumor necrosis factor receptor
    • Gary, D.S. et al. (1998) Ischemic and excitoxic brain injury is enhanced in mice lacking the small p55 tumor necrosis factor receptor. J. Cereb. Blood Flow Metab. 18, 1283-1287
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 1283-1287
    • Gary, D.S.1
  • 20
    • 0033178340 scopus 로고    scopus 로고
    • Exacerbation of damage and altered NFκB activation in mice lacking tumor necrosis factor receptor after traumatic brain injury
    • Sullivan, P.G. et al. (1999) Exacerbation of damage and altered NFκB activation in mice lacking tumor necrosis factor receptor after traumatic brain injury. J. Neurosci. 19, 6248-6256
    • (1999) J. Neurosci. , vol.19 , pp. 6248-6256
    • Sullivan, P.G.1
  • 21
    • 0033578435 scopus 로고    scopus 로고
    • Mechanisms of tumor necrosis factor α action on neurodegeneration: Interaction with insulin-like growth factor-1
    • Loddick, S.A. and Rothwell, N.J. (1999) Mechanisms of tumor necrosis factor α action on neurodegeneration: interaction with insulin-like growth factor-1. Proc. Natl. Acad. Sci. U. S. A. 96, 9449-9451
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 9449-9451
    • Loddick, S.A.1    Rothwell, N.J.2
  • 22
    • 0033593655 scopus 로고    scopus 로고
    • Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
    • Jiang, Y. et al. (1999) Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science 283, 543-546
    • (1999) Science , vol.283 , pp. 543-546
    • Jiang, Y.1
  • 23
    • 0033561763 scopus 로고    scopus 로고
    • Phosphatidylinositol 3′-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloid progenitors
    • Minshall, C. et al. (1999) Phosphatidylinositol 3′-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloid progenitors. J. Immunol. 162, 4542-4549
    • (1999) J. Immunol. , vol.162 , pp. 4542-4549
    • Minshall, C.1
  • 24
    • 0343765729 scopus 로고    scopus 로고
    • Rediscovering an old friend, IGF-I: Potential use in the treatment of neurodegenerative diseases
    • Dore, S. et al. (1997) Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases. Trends Neurosci. 20, 326-331
    • (1997) Trends Neurosci. , vol.20 , pp. 326-331
    • Dore, S.1
  • 25
    • 0030717725 scopus 로고    scopus 로고
    • Insulin-like growth factors regulate neuronal differentiation and survival
    • Feldman, E.L. (1997) Insulin-like growth factors regulate neuronal differentiation and survival. Neurobiol. Dis. 4, 201-214
    • (1997) Neurobiol. Dis. , vol.4 , pp. 201-214
    • Feldman, E.L.1
  • 26
    • 0032902685 scopus 로고    scopus 로고
    • Insulin-like growth factors as mediators of functional plasticity in the adult brain
    • Torres-Aleman, I. (1999) Insulin-like growth factors as mediators of functional plasticity in the adult brain. Harm. Metab. Res. 31, 114-119
    • (1999) Harm. Metab. Res. , vol.31 , pp. 114-119
    • Torres-Aleman, I.1
  • 27
    • 0030779032 scopus 로고    scopus 로고
    • Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: An electron microscopic study
    • Garcia-Segura, L.M. et al. (1997) Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study. J. Cytol. 26, 479-490
    • (1997) J. Cytol. , vol.26 , pp. 479-490
    • Garcia-Segura, L.M.1
  • 28
    • 0027314389 scopus 로고
    • 125I]insulin receptor binding sites in developing and adult rat brain
    • 125I]insulin receptor binding sites in developing and adult rat brain. J. Comp. Neurol. 333, 375-397
    • (1993) J. Comp. Neurol. , vol.333 , pp. 375-397
    • Kar, F.1
  • 29
    • 0032102110 scopus 로고    scopus 로고
    • The role of neuronal growth factors in neurodegenerative disorders of the human brain
    • Connor, B. and Dragunow, M. (1998) The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res. Rev. 1, 1-39
    • (1998) Brain Res. Rev. , vol.1 , pp. 1-39
    • Connor, B.1    Dragunow, M.2
  • 30
    • 0028941681 scopus 로고
    • IGF 1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
    • Beck, K.D. et al. (1995) IGF 1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron 14, 717-730
    • (1995) Neuron , vol.14 , pp. 717-730
    • Beck, K.D.1
  • 31
    • 0030953874 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells
    • Lin, X. and Bulleit, R. (1997) Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells. Dev. Brain Res. 99, 234-242
    • (1997) Dev. Brain Res. , vol.99 , pp. 234-242
    • Lin, X.1    Bulleit, R.2
  • 32
    • 0031053586 scopus 로고    scopus 로고
    • Regulation of neuronal survival by the serinethreonine protein kinase Akt
    • Dudek, H. et al. (1997) Regulation of neuronal survival by the serinethreonine protein kinase Akt. Science 275, 661-665
    • (1997) Science , vol.275 , pp. 661-665
    • Dudek, H.1
  • 33
    • 0030571588 scopus 로고    scopus 로고
    • Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult
    • Fernandez, A.M. et al. (1997) Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult. Neuroscience 76, 117-122
    • (1997) Neuroscience , vol.76 , pp. 117-122
    • Fernandez, A.M.1
  • 34
    • 0030828440 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor I and IGF binding protein 3 levels in patients with acute cerebral ischemic injury
    • Schwab, S. (1997) Plasma insulin-like growth factor I and IGF binding protein 3 levels in patients with acute cerebral ischemic injury. Stroke 28, 1744-1748
    • (1997) Stroke , vol.28 , pp. 1744-1748
    • Schwab, S.1
  • 35
    • 0026501096 scopus 로고
    • A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury
    • Gluckman, P. (1992) A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury. Biochem. Biophys. Res. Commun. 182, 593-599
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 593-599
    • Gluckman, P.1
  • 36
    • 0030071176 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs
    • Johnston, B.M. et al. (1996) Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs. J. Clin. Invest. 97, 300-308
    • (1996) J. Clin. Invest. , vol.97 , pp. 300-308
    • Johnston, B.M.1
  • 37
    • 13144279277 scopus 로고    scopus 로고
    • Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke
    • Loddick, S.A. et al. (1998) Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke. Proc. Natl. Acad. Sci. U. S. A. 95, 1894-1898
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 1894-1898
    • Loddick, S.A.1
  • 38
    • 0033525157 scopus 로고    scopus 로고
    • Central administration of insulin-like growth factor-1 inhibits lipopolysaccharide-induced sickness behavior in mice
    • Dantzer, R. et al. (1999) Central administration of insulin-like growth factor-1 inhibits lipopolysaccharide-induced sickness behavior in mice. NeuroReport 10, 289-292
    • (1999) NeuroReport , vol.10 , pp. 289-292
    • Dantzer, R.1
  • 39
    • 0033305581 scopus 로고    scopus 로고
    • Insulin-like growth factor I protects oligodendrocytes from tumor necrosis factor-α-induced injury
    • Ye, P. and D'Ercole, A.J. (1999) Insulin-like growth factor I protects oligodendrocytes from tumor necrosis factor-α-induced injury. Endocrinology 140, 3063-3072
    • (1999) Endocrinology , vol.140 , pp. 3063-3072
    • Ye, P.1    D'Ercole, A.J.2
  • 40
    • 0030667376 scopus 로고    scopus 로고
    • Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis
    • Hueber, A.O. et al. (1997) Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis. Science 278, 1305-1309
    • (1997) Science , vol.278 , pp. 1305-1309
    • Hueber, A.O.1
  • 41
    • 0033516674 scopus 로고    scopus 로고
    • Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway
    • Pastorino, J.G. et al. (1999) Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway. J. Biol. Chem. 274, 19411-19416
    • (1999) J. Biol. Chem. , vol.274 , pp. 19411-19416
    • Pastorino, J.G.1
  • 42
    • 0141542236 scopus 로고    scopus 로고
    • Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia
    • Fernandez, A.M. et al. (1998) Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia. Proc. Natl. Acad. Sci. U. S. A. 95, 1253-1258
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 1253-1258
    • Fernandez, A.M.1
  • 43
    • 0030933152 scopus 로고    scopus 로고
    • The genetic defect in ataxia-telangectasia
    • Lavin, M.F. and Shiloh, Y. (1997) The genetic defect in ataxia-telangectasia. Annu. Rev. Immunol. 15, 177-202
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 177-202
    • Lavin, M.F.1    Shiloh, Y.2
  • 44
    • 0030902595 scopus 로고    scopus 로고
    • Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- And human amylin-induced toxicity
    • Dore, S. et al. (1997) Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. Proc. Natl. Acad. Sci. U. S. A. 94, 4772-4777
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 4772-4777
    • Dore, S.1
  • 45
    • 0031595870 scopus 로고    scopus 로고
    • Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
    • Lawrence, C.B. et al. (1998) Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur. J. Neurosci. 10, 1188-1195
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1188-1195
    • Lawrence, C.B.1
  • 46
    • 0030839303 scopus 로고    scopus 로고
    • Antagonistic effects of interferon-gamma and interleukin-4 on flbroblast cultures
    • Serpier, H. et al. (1997) Antagonistic effects of interferon-gamma and interleukin-4 on flbroblast cultures, J. Invest. Dermatol. 109, 158-162
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 158-162
    • Serpier, H.1
  • 47
    • 0030892382 scopus 로고    scopus 로고
    • Interleukin-4 suppression of tumor necrosis factor α-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-κB
    • Bennett, B.L. et al. (1997) Interleukin-4 suppression of tumor necrosis factor α-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-κB. J. Biol. Chem. 272, 10212-10219
    • (1997) J. Biol. Chem. , vol.272 , pp. 10212-10219
    • Bennett, B.L.1
  • 48
    • 0030924558 scopus 로고    scopus 로고
    • Transient exposure of human myoblasts to tumor necrosis factor-α inhibits serum and insulin-like growth factor-I stimulated protein synthesis
    • Frost, R.A. et al. (1997) Transient exposure of human myoblasts to tumor necrosis factor-α inhibits serum and insulin-like growth factor-I stimulated protein synthesis. Endocrinology 138, 4153-4159
    • (1997) Endocrinology , vol.138 , pp. 4153-4159
    • Frost, R.A.1
  • 49
    • 0029933665 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
    • Peraldi, P. et al. (1996) Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J. Biol. Chem. 271, 13018-13022
    • (1996) J. Biol. Chem. , vol.271 , pp. 13018-13022
    • Peraldi, P.1
  • 50
    • 0030669392 scopus 로고    scopus 로고
    • A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
    • Paz, Y., et al. (1997) A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J. Biol. Chem. 272, 29911-29918
    • (1997) J. Biol. Chem. , vol.272 , pp. 29911-29918
    • Paz, Y.1
  • 51
    • 0030602178 scopus 로고    scopus 로고
    • Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis
    • Fernandez-Sanchez, M.T. et al. (1996) Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis. FEBS Lett. 398, 106-112
    • (1996) FEBS Lett. , vol.398 , pp. 106-112
    • Fernandez-Sanchez, M.T.1
  • 52
    • 0032508617 scopus 로고    scopus 로고
    • Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor
    • Dey, B.R. et al. (1998) Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor. J. Biol. Chem. 273, 24095-24101
    • (1998) J. Biol. Chem. , vol.273 , pp. 24095-24101
    • Dey, B.R.1
  • 53
    • 0029779883 scopus 로고    scopus 로고
    • Interleukin-1 blocks insulin and insulin-like growth factor-stimulated growth in MCF-7 human breast cancer cells by inhibiting receptor tyrosine kinase activity
    • Costantino, A. et al. (1996) Interleukin-1 blocks insulin and insulin-like growth factor-stimulated growth in MCF-7 human breast cancer cells by inhibiting receptor tyrosine kinase activity. Endocrinology 137, 4100-4107
    • (1996) Endocrinology , vol.137 , pp. 4100-4107
    • Costantino, A.1
  • 54
    • 0033144422 scopus 로고    scopus 로고
    • Etanercept: A review of its use in rheumatoid arthritis
    • Jarvis, B. and Faulds, D. (1999) Etanercept: a review of its use in rheumatoid arthritis. Drugs 57, 945-966
    • (1999) Drugs , vol.57 , pp. 945-966
    • Jarvis, B.1    Faulds, D.2
  • 55
    • 0032945382 scopus 로고    scopus 로고
    • Inhibitors of tumor necrosis factor for rheumatoid arthritis
    • Moreland, L.W. (1999) Inhibitors of tumor necrosis factor for rheumatoid arthritis. J. Rheumatol. 57, 7-15
    • (1999) J. Rheumatol. , vol.57 , pp. 7-15
    • Moreland, L.W.1
  • 56
    • 0027960171 scopus 로고
    • The role of cytokines in toxoplasmosis
    • Hunter, C.A. et al. (1994) The role of cytokines in toxoplasmosis. Biotherapy 7, 237-247
    • (1994) Biotherapy , vol.7 , pp. 237-247
    • Hunter, C.A.1
  • 57
    • 0023723833 scopus 로고
    • Newcastle disease virus as an anti-neoplastic agent: Induction of tumor necrosis factor-α and augmentation of its cytotoxicity
    • Lorence, R.M. et al. (1988) Newcastle disease virus as an anti-neoplastic agent: induction of tumor necrosis factor-α and augmentation of its cytotoxicity. J. Natl. Cancer Inst. 80, 1305-1312
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1305-1312
    • Lorence, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.