-
1
-
-
0037249712
-
Animal models of focal and global cerebral ischemia
-
R.J. Traystman Animal models of focal and global cerebral ischemia ILAR J. 44 2003 85 95
-
(2003)
ILAR J.
, vol.44
, pp. 85-95
-
-
Traystman, R.J.1
-
2
-
-
0034672943
-
Metabolism and functions of glutathione in brain
-
R. Dringen Metabolism and functions of glutathione in brain Prog. Neurobiol. 62 2000 649 671
-
(2000)
Prog. Neurobiol.
, vol.62
, pp. 649-671
-
-
Dringen, R.1
-
3
-
-
0017852672
-
Free radicals in cerebral ischemia
-
E.S. Flamm, H.B. Demopoulos, M.L. Seligman, R.G. Poser, and J. Ransohoff Free radicals in cerebral ischemia Stroke 9 1978 445 447
-
(1978)
Stroke
, vol.9
, pp. 445-447
-
-
Flamm, E.S.1
Demopoulos, H.B.2
Seligman, M.L.3
Poser, R.G.4
Ransohoff, J.5
-
4
-
-
0032845121
-
Ischemic cell death in brain neurons
-
P. Lipton Ischemic cell death in brain neurons Physiol. Rev. 79 1999 1431 1568
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
5
-
-
0025976701
-
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia
-
A.L. Betz, J. Randall, and D. Martz Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia Am. J. Physiol. 260 1991 H563 H568
-
(1991)
Am. J. Physiol.
, vol.260
-
-
Betz, A.L.1
Randall, J.2
Martz, D.3
-
6
-
-
0026351198
-
Role of xanthine deshydrogenase and oxidase in focal cerebral ischemic injury to rat
-
S. Lindsay, T.H. Liu, J.A. Xu, P.A. Marshall, J.K. Thompson, D.A. Parks, B.A. Freeman, C.Y. Hsu, and J.S. Beckman Role of xanthine deshydrogenase and oxidase in focal cerebral ischemic injury to rat Am. J. Physiol. 261 1991 H2051 H2057
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Lindsay, S.1
Liu, T.H.2
Xu, J.A.3
Marshall, P.A.4
Thompson, J.K.5
Parks, D.A.6
Freeman, B.A.7
Hsu, C.Y.8
Beckman, J.S.9
-
7
-
-
0024401539
-
Lipid peroxidation in focal cerebral ischemia
-
Y. Kinuta, H. Kiruchi, M. Ishikawa, M. Kimura, and Y. Itokawa Lipid peroxidation in focal cerebral ischemia J. Neurosurg. 71 1989 421 429
-
(1989)
J. Neurosurg.
, vol.71
, pp. 421-429
-
-
Kinuta, Y.1
Kiruchi, H.2
Ishikawa, M.3
Kimura, M.4
Itokawa, Y.5
-
8
-
-
0025831146
-
Neurochemical analysis of focal ischemia in rats
-
Y. Uemura, J.M. Miller, W.R. Matson, and M.F. Beal Neurochemical analysis of focal ischemia in rats Stroke 22 1991 1548 1553
-
(1991)
Stroke
, vol.22
, pp. 1548-1553
-
-
Uemura, Y.1
Miller, J.M.2
Matson, W.R.3
Beal, M.F.4
-
9
-
-
0031974368
-
Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency
-
K. Murakami, T. Kondo, M. Kawase, Y. Li, S. Sato, S.F. Chen, and P.H. Chan Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency J. Neurosci. 18 1998 205 213
-
(1998)
J. Neurosci.
, vol.18
, pp. 205-213
-
-
Murakami, K.1
Kondo, T.2
Kawase, M.3
Li, Y.4
Sato, S.5
Chen, S.F.6
Chan, P.H.7
-
10
-
-
0036192957
-
Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: Implications for the production and role of superoxide radicals
-
G.W. Kim, T. Kondo, N. Noshita, and P.H. Chan Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals Stroke 33 2002 809 815
-
(2002)
Stroke
, vol.33
, pp. 809-815
-
-
Kim, G.W.1
Kondo, T.2
Noshita, N.3
Chan, P.H.4
-
11
-
-
17344371804
-
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
-
J.N. Keller, M.S. Kindy, F.W. Holtsberg, D.K. St. Clai, H.-C. Yen, A. Germeyer, S.M. Steiner, A.J. Bruce-Keller, J.B. Hutchins, and M.P. Mattson Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction J. Neurosci. 18 1998 687 697
-
(1998)
J. Neurosci.
, vol.18
, pp. 687-697
-
-
Keller, J.N.1
Kindy, M.S.2
Holtsberg, F.W.3
St. Clai, D.K.4
Yen, H.-C.5
Germeyer, A.6
Steiner, S.M.7
Bruce-Keller, A.J.8
Hutchins, J.B.9
Mattson, M.P.10
-
12
-
-
0030909616
-
Cyclo-oxygenase gene expression in neurons contributes to ischemic brain damage
-
S. Nogawa, F. Zhang, M.E. Ross, and C. Iadecola Cyclo-oxygenase gene expression in neurons contributes to ischemic brain damage J. Neurosci. 17 1997 2746 2755
-
(1997)
J. Neurosci.
, vol.17
, pp. 2746-2755
-
-
Nogawa, S.1
Zhang, F.2
Ross, M.E.3
Iadecola, C.4
-
13
-
-
0028847050
-
Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: Effect of neutrophil depletion on extracellular ascorbyl radical formation
-
Y. Matsuo, T. Kihara, M. Ikeda, M. Ninomiya, H. Onodera, and K. Kogure Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: effect of neutrophil depletion on extracellular ascorbyl radical formation J. Cereb. Blood Flow Metab. 15 1995 941 947
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 941-947
-
-
Matsuo, Y.1
Kihara, T.2
Ikeda, M.3
Ninomiya, M.4
Onodera, H.5
Kogure, K.6
-
14
-
-
0142106472
-
Polymorphonuclear neutrophils contribute to infarction and oxidative stress in the cortex but not in the striatum after ischemia-reperfusion in rats
-
V. Beray-Berthat, N. Croci, M. Plotkine, and I. Margaill Polymorphonuclear neutrophils contribute to infarction and oxidative stress in the cortex but not in the striatum after ischemia-reperfusion in rats Brain Res. 987 2003 32 38
-
(2003)
Brain Res.
, vol.987
, pp. 32-38
-
-
Beray-Berthat, V.1
Croci, N.2
Plotkine, M.3
Margaill, I.4
-
15
-
-
0032930753
-
Superoxide anion production during reperfusion is reduced by an antineutrophil antibody after prolonged cerebral ischemia
-
R.H. Fabian, and T.A. Kent Superoxide anion production during reperfusion is reduced by an antineutrophil antibody after prolonged cerebral ischemia Free Radic. Biol. Med. 26 1999 355 361
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 355-361
-
-
Fabian, R.H.1
Kent, T.A.2
-
16
-
-
0030663253
-
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase
-
C.E. Walder, S.P. Green, W.C. Darbonne, J. Mathias, J. Rae, M.C. Dinauer, J.T. Curnutte, and G.R. Thoma Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase Stroke 28 1997 2252 2258
-
(1997)
Stroke
, vol.28
, pp. 2252-2258
-
-
Walder, C.E.1
Green, S.P.2
Darbonne, W.C.3
Mathias, J.4
Rae, J.5
Dinauer, M.C.6
Curnutte, J.T.7
Thoma, G.R.8
-
17
-
-
0033565586
-
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage
-
M.J.L. Eliasson, Z. Huang, R.J. Ferrante, M. Sasamata, M.E. Molliver, S.H. Snyder, and M.A. Moskowitz Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage J. Neurosci. 19 1999 5910 5918
-
(1999)
J. Neurosci.
, vol.19
, pp. 5910-5918
-
-
Eliasson, M.J.L.1
Huang, Z.2
Ferrante, R.J.3
Sasamata, M.4
Molliver, M.E.5
Snyder, S.H.6
Moskowitz, M.A.7
-
18
-
-
0033580967
-
7-Nitroindazole attenuates nitrotyrosine formation in the early phase of cerebral ischemia-reperfusion in mice
-
H. Hirabayashi, S. Takizawa, N. Fukuyama, H. Nakazawa, and Y. Shinohara 7-Nitroindazole attenuates nitrotyrosine formation in the early phase of cerebral ischemia-reperfusion in mice Neurosci. Lett. 268 1999 111 113
-
(1999)
Neurosci. Lett.
, vol.268
, pp. 111-113
-
-
Hirabayashi, H.1
Takizawa, S.2
Fukuyama, N.3
Nakazawa, H.4
Shinohara, Y.5
-
19
-
-
0033510012
-
Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion
-
S. Takizawa, N. Fukuyama, H. Hirabayashi, H. Nakazawa, and Y. Shinohara Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion J. Cereb. Blood Flow Metab. 19 1999 667 672
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 667-672
-
-
Takizawa, S.1
Fukuyama, N.2
Hirabayashi, H.3
Nakazawa, H.4
Shinohara, Y.5
-
20
-
-
0033985973
-
Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion
-
H. Hirabayashi, S. Takizawa, N. Fukuyama, H. Nakazawa, and Y. Shinohara Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion Brain Res. 852 2000 319 325
-
(2000)
Brain Res.
, vol.852
, pp. 319-325
-
-
Hirabayashi, H.1
Takizawa, S.2
Fukuyama, N.3
Nakazawa, H.4
Shinohara, Y.5
-
21
-
-
0035200650
-
Antisense oligodeoxynucleotide to inducible nitric oxide synthase protects against transient focal cerebral ischemia-induced brain injury
-
S. Parmentier-Batteur, G.A. Böhme, D. Lerouet, L. Zhou-Ding, V. Beray, I. Margaill, and M. Plotkine Antisense oligodeoxynucleotide to inducible nitric oxide synthase protects against transient focal cerebral ischemia-induced brain injury J. Cereb. Blood Flow Metab. 21 2001 15 21
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 15-21
-
-
Parmentier-Batteur, S.1
Böhme, G.A.2
Lerouet, D.3
Zhou-Ding, L.4
Beray, V.5
Margaill, I.6
Plotkine, M.7
-
22
-
-
0036561798
-
Lipid peroxidation in rat brain during focal cerebral ischemia: Prevention of malondialdehyde and lipid conjugated diene production by a novel antiepileptic, lamotrigine
-
M. Serteser, T. Ozben, S. Gumuslu, S. Balkan, and E. Balkan Lipid peroxidation in rat brain during focal cerebral ischemia: prevention of malondialdehyde and lipid conjugated diene production by a novel antiepileptic, lamotrigine Neurotoxicology 23 2002 111 119
-
(2002)
Neurotoxicology
, vol.23
, pp. 111-119
-
-
Serteser, M.1
Ozben, T.2
Gumuslu, S.3
Balkan, S.4
Balkan, E.5
-
23
-
-
0029101066
-
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: Possible implication in tissue damage
-
E. Lancelot, J. Callebert, M.-L. Revaud, R.G. Boulu, and M. Plotkine Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage Neurosci. Lett. 197 1995 85 88
-
(1995)
Neurosci. Lett.
, vol.197
, pp. 85-88
-
-
Lancelot, E.1
Callebert, J.2
Revaud, M.-L.3
Boulu, R.G.4
Plotkine, M.5
-
24
-
-
0037897557
-
The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia
-
N. Kato, K. Yanaka, S. Nagase, A. Hirayama, and T. Nose The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia Acta Neurochir. (Wien) 145 2003 489 493
-
(2003)
Acta Neurochir. (Wien)
, vol.145
, pp. 489-493
-
-
Kato, N.1
Yanaka, K.2
Nagase, S.3
Hirayama, A.4
Nose, T.5
-
25
-
-
0028797945
-
In vivo detection of superoxide anion production by the brain using a cytochrome c electrode
-
R.H. Fabian, D.S. DeWitt, and T.A. Kent In vivo detection of superoxide anion production by the brain using a cytochrome c electrode J. Cereb. Blood Flow Metab. 15 1995 242 247
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 242-247
-
-
Fabian, R.H.1
Dewitt, D.S.2
Kent, T.A.3
-
26
-
-
0026555334
-
Depletion of brain glutathione by buthione sulfoximine enhances cerebral ischemic injury in rats
-
T. Mizui, H. Kinouchi, and P.H. Chan Depletion of brain glutathione by buthione sulfoximine enhances cerebral ischemic injury in rats Am. J. Physiol. 262 1992 H313 H317
-
(1992)
Am. J. Physiol.
, vol.262
-
-
Mizui, T.1
Kinouchi, H.2
Chan, P.H.3
-
27
-
-
3342978256
-
Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: Effect of dietary fish oil
-
S. Choi-Kwon, K.A. Park, H.J. Lee, M.S. Park, J.H. Lee, S.E. Jeon, M.A. Choe, and K.C. Park Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: effect of dietary fish oil Brain Res. Dev. Brain Res. 152 2004 11 18
-
(2004)
Brain Res. Dev. Brain Res.
, vol.152
, pp. 11-18
-
-
Choi-Kwon, S.1
Park, K.A.2
Lee, H.J.3
Park, M.S.4
Lee, J.H.5
Jeon, S.E.6
Choe, M.A.7
Park, K.C.8
-
28
-
-
0037146917
-
Changes in oxidative stress, iNOS activity and neutrophil infiltration in severe transient focal cerebral ischemia in rats
-
D. Lerouet, V. Beray-Berthat, B. Palmier, M. Plotkine, and I. Margaill Changes in oxidative stress, iNOS activity and neutrophil infiltration in severe transient focal cerebral ischemia in rats Brain Res. 958 2002 166 175
-
(2002)
Brain Res.
, vol.958
, pp. 166-175
-
-
Lerouet, D.1
Beray-Berthat, V.2
Palmier, B.3
Plotkine, M.4
Margaill, I.5
-
29
-
-
0030844146
-
Differential induction of superoxide dismutase in core and penumbra regions after transient focal ischemia in the rat neocortex
-
T. Toyoda, and K.S. Lee Differential induction of superoxide dismutase in core and penumbra regions after transient focal ischemia in the rat neocortex Neurosci. Lett. 235 1997 29 32
-
(1997)
Neurosci. Lett.
, vol.235
, pp. 29-32
-
-
Toyoda, T.1
Lee, K.S.2
-
30
-
-
0031958641
-
Plasma levels of antioxidant vitamins, selenium, total sulfhydryl, groups and oxidative products in ischemic-stroke patients as compared to matched controls in Taiwan
-
C.Y. Chang, Y.C. Lai, T.J. Cheng, M.T. Lau, and M.L. Hu Plasma levels of antioxidant vitamins, selenium, total sulfhydryl, groups and oxidative products in ischemic-stroke patients as compared to matched controls in Taiwan Free Radic. Res. 28 1998 15 24
-
(1998)
Free Radic. Res.
, vol.28
, pp. 15-24
-
-
Chang, C.Y.1
Lai, Y.C.2
Cheng, T.J.3
Lau, M.T.4
Hu, M.L.5
-
31
-
-
0033855267
-
Oxidative stress in the context of acute cerebrovascular stroke
-
M.M.H. El Kossi, and M.M. Zakhary Oxidative stress in the context of acute cerebrovascular stroke Stroke 31 2000 1889 1892
-
(2000)
Stroke
, vol.31
, pp. 1889-1892
-
-
El Kossi, M.M.H.1
Zakhary, M.M.2
-
32
-
-
3042793193
-
Dynamics of free radical processes in acute ischemic stroke: Influence on neurological status and outcome
-
M. Alexandrova, P. Bochev, V. Markova, B. Bechev, M. Popova, M. Danovska, and V. Simeonova Dynamics of free radical processes in acute ischemic stroke: influence on neurological status and outcome J. Clin. Neurosci. 11 2004 501 506
-
(2004)
J. Clin. Neurosci.
, vol.11
, pp. 501-506
-
-
Alexandrova, M.1
Bochev, P.2
Markova, V.3
Bechev, B.4
Popova, M.5
Danovska, M.6
Simeonova, V.7
-
34
-
-
0035122243
-
Malonaldehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia
-
S. Demirkaya, M.A. Topcuoglu, A. Aydin, U.H. Ulas, A.I. Isimer, and O. Vural Malonaldehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia Eur. J. Neurol. 8 2001 43 51
-
(2001)
Eur. J. Neurol.
, vol.8
, pp. 43-51
-
-
Demirkaya, S.1
Topcuoglu, M.A.2
Aydin, A.3
Ulas, U.H.4
Isimer, A.I.5
Vural, O.6
-
35
-
-
0032171620
-
Increased plasma levels of lipid hydroperoxydes in patients with ischemic stroke
-
M.C. Polidori, B. Frei, A. Cherubini, G. Nelles, G. Rordorf, J.F. Keaney Jr., L. Schwamm, P. Mecocci, W.J. Koroshetz, and F. Beal Increased plasma levels of lipid hydroperoxydes in patients with ischemic stroke Free Radic. Biol. Med. 25 1998 561 567
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 561-567
-
-
Polidori, M.C.1
Frei, B.2
Cherubini, A.3
Nelles, G.4
Rordorf, G.5
Keaney Jr., J.F.6
Schwamm, L.7
Mecocci, P.8
Koroshetz, W.J.9
Beal, F.10
-
36
-
-
0033800597
-
Antoxidant profile and early outcome in stroke patients
-
A. Cherubini, M.C. Polidori, M. Bregnocchi, S. Pezzuto, R. Cecchetti, T. Ingnegni, A. di Iori, U. Senin, and P. Mecocci Antoxidant profile and early outcome in stroke patients Stroke 31 2000 2295 2300
-
(2000)
Stroke
, vol.31
, pp. 2295-2300
-
-
Cherubini, A.1
Polidori, M.C.2
Bregnocchi, M.3
Pezzuto, S.4
Cecchetti, R.5
Ingnegni, T.6
Di Iori, A.7
Senin, U.8
Mecocci, P.9
-
37
-
-
0028268452
-
Increase in superoxide dismutase after cerebrovascular accident
-
N. Gruener, B. Gross, O. Gozlan, and M. Barak Increase in superoxide dismutase after cerebrovascular accident Life Sci. 54 1994 711 713
-
(1994)
Life Sci.
, vol.54
, pp. 711-713
-
-
Gruener, N.1
Gross, B.2
Gozlan, O.3
Barak, M.4
-
38
-
-
0026549570
-
Release of superoxide dismutase into cerebrospinal fluid as a marker of brain lesion in acute cerebral infarction
-
T. Strand, and S.L. Marklund Release of superoxide dismutase into cerebrospinal fluid as a marker of brain lesion in acute cerebral infarction Stroke 23 1992 515 518
-
(1992)
Stroke
, vol.23
, pp. 515-518
-
-
Strand, T.1
Marklund, S.L.2
-
39
-
-
0031439424
-
Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury. Correlation with clinical course and infarct size
-
M. Spranger, S. Krempien, S. Schwab, S. Donneberg, and W. Hacke Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury. Correlation with clinical course and infarct size Stroke 28 1997 2425 2428
-
(1997)
Stroke
, vol.28
, pp. 2425-2428
-
-
Spranger, M.1
Krempien, S.2
Schwab, S.3
Donneberg, S.4
Hacke, W.5
-
40
-
-
0033963330
-
Low plasma antioxidant activity is associated with high lesion volume and neurological impairment in stroke
-
J.S. Leinonen, J.-P. Ahonen, K. Lönnrot, M. Jehkonen, P. Dastidar, G. Molnár, and H. Alho Low plasma antioxidant activity is associated with high lesion volume and neurological impairment in stroke Stroke 31 2000 33 39
-
(2000)
Stroke
, vol.31
, pp. 33-39
-
-
Leinonen, J.S.1
Ahonen, J.-P.2
Lönnrot, K.3
Jehkonen, M.4
Dastidar, P.5
Molnár, G.6
Alho, H.7
-
41
-
-
0036221193
-
Prognostic significance of uric acid serum concentration in patients with acute ischemic stroke
-
Á. Chamorro, V. Obach, Á. Cervera, M. Revilla, R. Deulofeu, and J.H. Aponte Prognostic significance of uric acid serum concentration in patients with acute ischemic stroke Stroke 33 2002 1048 1052
-
(2002)
Stroke
, vol.33
, pp. 1048-1052
-
-
Chamorro, Á.1
Obach, V.2
Cervera, Á.3
Revilla, M.4
Deulofeu, R.5
Aponte, J.H.6
-
42
-
-
0026739140
-
Use of allopurinol and deferoxamine in cellular protection during ischemia
-
D.S. Soloniuk, E. Perkins, and J.R. Wilson Use of allopurinol and deferoxamine in cellular protection during ischemia Surg. Neurol. 38 1992 110 113
-
(1992)
Surg. Neurol.
, vol.38
, pp. 110-113
-
-
Soloniuk, D.S.1
Perkins, E.2
Wilson, J.R.3
-
43
-
-
0025876608
-
Oxypurinol reduces focal ischemic brain injury in the rat
-
Y. Lin, and J.W. Phillis Oxypurinol reduces focal ischemic brain injury in the rat Neurosci. Lett. 126 1991 187 190
-
(1991)
Neurosci. Lett.
, vol.126
, pp. 187-190
-
-
Lin, Y.1
Phillis, J.W.2
-
44
-
-
0026512905
-
Deoxycoformycin and oxypurinol: Protection against focal ischemic brain injury in the rat
-
Y. Lin, and J.W. Phillis Deoxycoformycin and oxypurinol: protection against focal ischemic brain injury in the rat Brain Res. 571 1992 272 280
-
(1992)
Brain Res.
, vol.571
, pp. 272-280
-
-
Lin, Y.1
Phillis, J.W.2
-
45
-
-
0037449409
-
Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia
-
K. Sugimoto, and C. Iadecola Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia Brain Res. 960 2003 273 276
-
(2003)
Brain Res.
, vol.960
, pp. 273-276
-
-
Sugimoto, K.1
Iadecola, C.2
-
46
-
-
1942439029
-
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat
-
E. Candelario-Jalil, A. Gonzalez-Falcon, M. Garcia-Cabrera, O.S. Leon, and B.L. Fiebich Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat Brain Res. 1007 2004 98 108
-
(2004)
Brain Res.
, vol.1007
, pp. 98-108
-
-
Candelario-Jalil, E.1
Gonzalez-Falcon, A.2
Garcia-Cabrera, M.3
Leon, O.S.4
Fiebich, B.L.5
-
47
-
-
0035075997
-
Efficacy of antioxidant therapies in transient focal ischemia in mice
-
W.M. Clark, L.G. Rinker, N.S. Lessos, S.L. Lowery, and M.J. Cipolla Efficacy of antioxidant therapies in transient focal ischemia in mice Stroke 32 2001 1000 1004
-
(2001)
Stroke
, vol.32
, pp. 1000-1004
-
-
Clark, W.M.1
Rinker, L.G.2
Lessos, N.S.3
Lowery, S.L.4
Cipolla, M.J.5
-
48
-
-
0008587780
-
Nuclear factor-κB activation during cerebral reperfusion: Effect of attenuation with N-acetylcysteine treatment
-
J.E. Carroll, E.F. Howard, D.C. Hess, C.G. Wakade, Q. Chen, and C. Cheng Nuclear factor-κB activation during cerebral reperfusion: effect of attenuation with N-acetylcysteine treatment Mol. Brain Res. 56 1998 186 191
-
(1998)
Mol. Brain Res.
, vol.56
, pp. 186-191
-
-
Carroll, J.E.1
Howard, E.F.2
Hess, D.C.3
Wakade, C.G.4
Chen, Q.5
Cheng, C.6
-
49
-
-
2342562573
-
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke
-
M. Khan, B. Sekhon, M. Jatana, S. Giri, A.G. Gilg, C. Sekhon, I. Singh, and A.K. Singh Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke J. Neurosci. Res. 76 2004 519 527
-
(2004)
J. Neurosci. Res.
, vol.76
, pp. 519-527
-
-
Khan, M.1
Sekhon, B.2
Jatana, M.3
Giri, S.4
Gilg, A.G.5
Sekhon, C.6
Singh, I.7
Singh, A.K.8
-
50
-
-
0346787815
-
Glutathione monoethyl ester provides neuroprotection in a rat model of stroke
-
M.F. Anderson, M. Nilsson, P.S. Eriksson, and N.R. Sims Glutathione monoethyl ester provides neuroprotection in a rat model of stroke Neurosci. Lett. 354 2004 163 165
-
(2004)
Neurosci. Lett.
, vol.354
, pp. 163-165
-
-
Anderson, M.F.1
Nilsson, M.2
Eriksson, P.S.3
Sims, N.R.4
-
51
-
-
0028181531
-
α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia
-
X. Cao, and J.W. Phillis α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia Brain Res. 644 1994 267 272
-
(1994)
Brain Res.
, vol.644
, pp. 267-272
-
-
Cao, X.1
Phillis, J.W.2
-
52
-
-
0027937751
-
Delayed treatment with the spin trap α-phenyl-n-tert-butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats
-
Q. Zhao, K. Pahlmark, M.-L. Smith, and B.K. Siesjö Delayed treatment with the spin trap α-phenyl-n-tert-butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats Acta Physiol. Scand. 152 1994 349 350
-
(1994)
Acta Physiol. Scand.
, vol.152
, pp. 349-350
-
-
Zhao, Q.1
Pahlmark, K.2
Smith, M.-L.3
Siesjö, B.K.4
-
53
-
-
0031003370
-
Facilitation of postischemic reperfusion with α-PBN: Assessment using NMR and doppler flow techniques
-
J.B. Schulz, N. Panahian, Y.I. Chen, M.F. Beal, M.A. Moskowitz, B.R. Rosen, and B.G. Jenkins Facilitation of postischemic reperfusion with α-PBN: assessment using NMR and doppler flow techniques Am. J. Physiol. 272 1997 H1986 H1995
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Schulz, J.B.1
Panahian, N.2
Chen, Y.I.3
Beal, M.F.4
Moskowitz, M.A.5
Rosen, B.R.6
Jenkins, B.G.7
-
54
-
-
0034724791
-
Neurological impairment in rats after transient middle cerebral artery occlusion: A comparative study under various treatment paradigms
-
S. Zausinger, E. Hungerhuber, A. Baethmann, H.-J. Reulen, and R. Schmid-Elsaesser Neurological impairment in rats after transient middle cerebral artery occlusion: a comparative study under various treatment paradigms Brain Res. 863 2000 94 105
-
(2000)
Brain Res.
, vol.863
, pp. 94-105
-
-
Zausinger, S.1
Hungerhuber, E.2
Baethmann, A.3
Reulen, H.-J.4
Schmid-Elsaesser, R.5
-
55
-
-
0141987868
-
The free radical spin-trap alpha-PBN attenuates periinfarct depolarizations following permanent middle cerebral artery occlusion in rats without reducing infarct volume
-
T. Christensen, T. Bruhn, and N.H. Diemer The free radical spin-trap alpha-PBN attenuates periinfarct depolarizations following permanent middle cerebral artery occlusion in rats without reducing infarct volume Brain Res. 990 2003 66 76
-
(2003)
Brain Res.
, vol.990
, pp. 66-76
-
-
Christensen, T.1
Bruhn, T.2
Diemer, N.H.3
-
56
-
-
0034073967
-
Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2- sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia
-
Y. Yang, Q. Li, and A. Shuaib Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia Exp. Neurol. 163 2000 39 45
-
(2000)
Exp. Neurol.
, vol.163
, pp. 39-45
-
-
Yang, Y.1
Li, Q.2
Shuaib, A.3
-
57
-
-
0033502692
-
Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat
-
S. Kuroda, R. Tsuchidate, M.-L. Smith, K.R. Maples, and B.K. Siesjö Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat J. Cereb. Blood Flow Metab. 19 1999 778 787
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 778-787
-
-
Kuroda, S.1
Tsuchidate, R.2
Smith, M.-L.3
Maples, K.R.4
Siesjö, B.K.5
-
58
-
-
0036152938
-
Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; Studies on dose, plasma concentration and therapeutic time window
-
S.G. Sydserff, A.R. Borelli, A.R. Green, and A.J. Cross Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window Br. J. Pharmacol. 135 2002 103 112
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 103-112
-
-
Sydserff, S.G.1
Borelli, A.R.2
Green, A.R.3
Cross, A.J.4
-
59
-
-
0042837942
-
Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia
-
M.D. Ginsberg, D.A. Becker, R. Busto, A. Belayev, Y. Zhang, L. Khoutorova, J.J. Ley, W. Zhao, and L. Belayev Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia Ann. Neurol. 54 2003 330 342
-
(2003)
Ann. Neurol.
, vol.54
, pp. 330-342
-
-
Ginsberg, M.D.1
Becker, D.A.2
Busto, R.3
Belayev, A.4
Zhang, Y.5
Khoutorova, L.6
Ley, J.J.7
Zhao, W.8
Belayev, L.9
-
60
-
-
0028271830
-
Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia
-
C.K. Park, and E.D. Hall Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia Brain Res. 645 1994 157 163
-
(1994)
Brain Res.
, vol.645
, pp. 157-163
-
-
Park, C.K.1
Hall, E.D.2
-
61
-
-
0026652877
-
Tirilazad reduces cortical infarction after transient but not permanent focal cerebral ischemia in rats
-
D. Xue, A. Slivka, and A.M. Buchan Tirilazad reduces cortical infarction after transient but not permanent focal cerebral ischemia in rats Stroke 23 1992 894 899
-
(1992)
Stroke
, vol.23
, pp. 894-899
-
-
Xue, D.1
Slivka, A.2
Buchan, A.M.3
-
62
-
-
0346232735
-
Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo
-
Z.F. Yu, A.J. Bruce-Keller, Y. Goodman, and M.P. Mattson Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo J. Neurosci. Res. 53 1998 613 625
-
(1998)
J. Neurosci. Res.
, vol.53
, pp. 613-625
-
-
Yu, Z.F.1
Bruce-Keller, A.J.2
Goodman, Y.3
Mattson, M.P.4
-
63
-
-
12744273107
-
When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke
-
R.J. Reiter, D.X. Tan, J. Leon, U. Kilic, and E. Kilic When melatonin gets on your nerves: its beneficial actions in experimental models of stroke Exp. Biol. Med. (Maywood) 230 2005 104 117
-
(2005)
Exp. Biol. Med. (Maywood)
, vol.230
, pp. 104-117
-
-
Reiter, R.J.1
Tan, D.X.2
Leon, J.3
Kilic, U.4
Kilic, E.5
-
64
-
-
0033509001
-
Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia
-
E. Kilic, Y.G. Özdemir, H. Bolay, H. Kelestimur, and T. Dalkara Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia J. Cereb. Blood Flow Metab. 19 1999 511 516
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 511-516
-
-
Kilic, E.1
Özdemir, Y.G.2
Bolay, H.3
Kelestimur, H.4
Dalkara, T.5
-
65
-
-
0036468920
-
Pre-treatment with melatonin reduces volume of cerebral infarction in a permanent middle cerebral artery occlusion stroke model in the rat
-
Z. Pei, H.T.S. Ho, and R.T.F. Cheung Pre-treatment with melatonin reduces volume of cerebral infarction in a permanent middle cerebral artery occlusion stroke model in the rat Neurosci. Lett. 318 2002 141 144
-
(2002)
Neurosci. Lett.
, vol.318
, pp. 141-144
-
-
Pei, Z.1
Ho, H.T.S.2
Cheung, R.T.F.3
-
66
-
-
7644233478
-
Prophylactic use of melatonin protects against focal cerebral ischemia in mice: Role of endothelin converting enzyme-1
-
E. Kilic, U. Kilic, R.J. Reiter, C.L. Bassetti, and D.M. Hermann Prophylactic use of melatonin protects against focal cerebral ischemia in mice: role of endothelin converting enzyme-1 J. Pineal. Res. 37 2004 247 251
-
(2004)
J. Pineal. Res.
, vol.37
, pp. 247-251
-
-
Kilic, E.1
Kilic, U.2
Reiter, R.J.3
Bassetti, C.L.4
Hermann, D.M.5
-
67
-
-
0345084499
-
Dietary vitamin e levels affect outcome of permanent focal cerebral ischemia in rats
-
H.B. van der Worp, P.R. Bär, L.J. Kappelle, and D.J. de Wildt Dietary vitamin E levels affect outcome of permanent focal cerebral ischemia in rats Stroke 29 1998 1002 1006
-
(1998)
Stroke
, vol.29
, pp. 1002-1006
-
-
Van Der Worp, H.B.1
Bär, P.R.2
Kappelle, L.J.3
De Wildt, D.J.4
-
68
-
-
0037472341
-
Vitamin e isoforms alpha-tocotrienol and gamma-tocopherol prevent cerebral infarction in mice
-
K. Mishima, T. Tanaka, F. Pu, N. Egashira, K. Iwasaki, R. Hidaka, K. Matsunaga, J. Takata, Y. Karube, and M. Fujiwara Vitamin E isoforms alpha-tocotrienol and gamma-tocopherol prevent cerebral infarction in mice Neurosci. Lett. 337 2003 56 60
-
(2003)
Neurosci. Lett.
, vol.337
, pp. 56-60
-
-
Mishima, K.1
Tanaka, T.2
Pu, F.3
Egashira, N.4
Iwasaki, K.5
Hidaka, R.6
Matsunaga, K.7
Takata, J.8
Karube, Y.9
Fujiwara, M.10
-
69
-
-
0141516535
-
An alpha-lipoic acid-vitamin e mixture reduces post-embolism lipid peroxidation, cerebral infarction, and neurological deficit in rats
-
J. Garcia-Estrada, O. Gonzalez-Perez, R.E. Gonzalez-Castaneda, A. Martinez-Contreras, S. Luquin, P.G. de la Mora, and A. Navarro-Ruiz An alpha-lipoic acid-vitamin E mixture reduces post-embolism lipid peroxidation, cerebral infarction, and neurological deficit in rats Neurosci. Res. 47 2003 219 224
-
(2003)
Neurosci. Res.
, vol.47
, pp. 219-224
-
-
Garcia-Estrada, J.1
Gonzalez-Perez, O.2
Gonzalez-Castaneda, R.E.3
Martinez-Contreras, A.4
Luquin, S.5
De La Mora, P.G.6
Navarro-Ruiz, A.7
-
70
-
-
0035949516
-
Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
-
J. Huang, D.B. Agus, C.J. Winfree, S. Kiss, W.J. Mack, R.A. McTaggart, T.F. Choudhri, L.J. Kim, J. Mocco, D.J. Pinsky, W.D. Fox, R.J. Israel, T.A. Boyd, D.W. Golde, and E.S. Connolly Jr Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke Proc. Natl. Acad. Sci. USA 98 2001 11720 11724
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11720-11724
-
-
Huang, J.1
Agus, D.B.2
Winfree, C.J.3
Kiss, S.4
MacK, W.J.5
McTaggart, R.A.6
Choudhri, T.F.7
Kim, L.J.8
Mocco, J.9
Pinsky, D.J.10
Fox, W.D.11
Israel, R.J.12
Boyd, T.A.13
Golde, D.W.14
Connolly Jr., E.S.15
-
71
-
-
0031879442
-
Hydroxyl radical generation after the third hour following ischemia contributes to brain damage
-
H. Takamatsu, K. Kondo, Y. Ikeda, and K. Umemura Hydroxyl radical generation after the third hour following ischemia contributes to brain damage Eur. J. Pharmacol. 352 1998 165 169
-
(1998)
Eur. J. Pharmacol.
, vol.352
, pp. 165-169
-
-
Takamatsu, H.1
Kondo, K.2
Ikeda, Y.3
Umemura, K.4
-
72
-
-
0037189154
-
Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats
-
K. Sinha, G. Chaudhary, and Y.K. Gupta Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats Life Sci. 71 2002 655 665
-
(2002)
Life Sci.
, vol.71
, pp. 655-665
-
-
Sinha, K.1
Chaudhary, G.2
Gupta, Y.K.3
-
73
-
-
3142655732
-
Oxyresveratrol (trans-2,3′,4,5′-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia
-
S.A. Andrabi, M.G. Spina, P. Lorenz, U. Ebmeyer, G. Wolf, and T.F. Horn Oxyresveratrol (trans-2,3′,4,5′-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia Brain Res. 1017 2004 98 107
-
(2004)
Brain Res.
, vol.1017
, pp. 98-107
-
-
Andrabi, S.A.1
Spina, M.G.2
Lorenz, P.3
Ebmeyer, U.4
Wolf, G.5
Horn, T.F.6
-
74
-
-
0032054483
-
Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion
-
A. Mizuno, K. Umemura, and M. Nakashima Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion Gen. Pharm. 30 1998 575 578
-
(1998)
Gen. Pharm.
, vol.30
, pp. 575-578
-
-
Mizuno, A.1
Umemura, K.2
Nakashima, M.3
-
75
-
-
7944234144
-
Neuroprotective effects of the free radical scavenger Edaravone (MCI-186) in mice permanent focal brain ischemia
-
H. Shichinohe, S. Kuroda, H. Yasuda, T. Ishikawa, M. Iwai, M. Horiuchi, and Y. Iwasaki Neuroprotective effects of the free radical scavenger Edaravone (MCI-186) in mice permanent focal brain ischemia Brain Res. 1029 2004 200 206
-
(2004)
Brain Res.
, vol.1029
, pp. 200-206
-
-
Shichinohe, H.1
Kuroda, S.2
Yasuda, H.3
Ishikawa, T.4
Iwai, M.5
Horiuchi, M.6
Iwasaki, Y.7
-
76
-
-
0031214495
-
Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats
-
J.W. Francis, J.M. Ren, L. Warren, R.H. Brown, and S.P. Finklestein Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats Exp. Neurol. 146 1997 435 443
-
(1997)
Exp. Neurol.
, vol.146
, pp. 435-443
-
-
Francis, J.W.1
Ren, J.M.2
Warren, L.3
Brown, R.H.4
Finklestein, S.P.5
-
77
-
-
0025074716
-
Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats
-
S. Imaizumi, V. Woolworth, R.A. Fishman, and P.H. Chan Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats Stroke 21 1990 1312 1317
-
(1990)
Stroke
, vol.21
, pp. 1312-1317
-
-
Imaizumi, S.1
Woolworth, V.2
Fishman, R.A.3
Chan, P.H.4
-
78
-
-
0027236065
-
Polyethylene glycol-conjugated superoxide dismutase in focal cerebral ischemia-reperfusion
-
Y.Y. He, C.Y. Hsu, A.M. Ezrin, and M.S. Miller Polyethylene glycol-conjugated superoxide dismutase in focal cerebral ischemia-reperfusion Am. J. Physiol. 265 1993 H252 H256
-
(1993)
Am. J. Physiol.
, vol.265
-
-
He, Y.Y.1
Hsu, C.Y.2
Ezrin, A.M.3
Miller, M.S.4
-
79
-
-
0024571782
-
Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
-
T.H. Liu, J.S. Beckman, B.A. Freeman, E.L. Hogan, and C.Y. Hsu Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury Am. J. Physiol. 256 1989 H589 H593
-
(1989)
Am. J. Physiol.
, vol.256
-
-
Liu, T.H.1
Beckman, J.S.2
Freeman, B.A.3
Hogan, E.L.4
Hsu, C.Y.5
-
80
-
-
0037435874
-
Protective effect of a new nonpeptidyl mimetic of SOD, M40401, against focal cerebral ischemia in the rat
-
K. Shimizu, N. Rajapakse, T. Horiguchi, R.M. Payne, and D.W. Busija Protective effect of a new nonpeptidyl mimetic of SOD, M40401, against focal cerebral ischemia in the rat Brain Res. 963 2003 8 14
-
(2003)
Brain Res.
, vol.963
, pp. 8-14
-
-
Shimizu, K.1
Rajapakse, N.2
Horiguchi, T.3
Payne, R.M.4
Busija, D.W.5
-
81
-
-
0035399884
-
Neuroprotection from delayed postoschemic administration of a metalloporphyrin vatalytic antioxidant
-
G.B. Mackensen, M. Patel, H. Sheng, C.L. Calvi, I. Batinic-Haberle, B.J. Day, L.P. Liang, I. Fridovich, J.D. Crapo, R.D. Peralstein, and D.S. Warner Neuroprotection from delayed postoschemic administration of a metalloporphyrin vatalytic antioxidant J. Neurosci. 21 2001 4582 4592
-
(2001)
J. Neurosci.
, vol.21
, pp. 4582-4592
-
-
MacKensen, G.B.1
Patel, M.2
Sheng, H.3
Calvi, C.L.4
Batinic-Haberle, I.5
Day, B.J.6
Liang, L.P.7
Fridovich, I.8
Crapo, J.D.9
Peralstein, R.D.10
Warner, D.S.11
-
82
-
-
18644383755
-
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia
-
H. Sheng, J.J. Enghild, R. Bowler, M. Patel, I. Batinic-Haberle, C.L. Calvi, B.J. Day, R.D. Pearlstein, J.D. Crapo, and D.S. Warner Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia Free Radic. Biol. Med. 33 2002 947 961
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 947-961
-
-
Sheng, H.1
Enghild, J.J.2
Bowler, R.3
Patel, M.4
Batinic-Haberle, I.5
Calvi, C.L.6
Day, B.J.7
Pearlstein, R.D.8
Crapo, J.D.9
Warner, D.S.10
-
83
-
-
0031911994
-
Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury
-
K. Baker, C.B. Marcus, K. Huffman, H. Kruk, B. Malfroy, and S.R. Doctrow Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury J. Pharmacol. Exp. Ther. 284 1998 215 221
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 215-221
-
-
Baker, K.1
Marcus, C.B.2
Huffman, K.3
Kruk, H.4
Malfroy, B.5
Doctrow, S.R.6
-
84
-
-
1542327575
-
Catalase over-expression protects striatal neurons from transient focal cerebral ischemia
-
W. Gu, H. Zhao, M.A. Yenari, R.M. Sapolsky, and G.K. Steinberg Catalase over-expression protects striatal neurons from transient focal cerebral ischemia Neuroreport 15 2004 413 416
-
(2004)
Neuroreport
, vol.15
, pp. 413-416
-
-
Gu, W.1
Zhao, H.2
Yenari, M.A.3
Sapolsky, R.M.4
Steinberg, G.K.5
-
85
-
-
0030734080
-
Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral occlusion
-
T. Takasago, E.E. Peters, D.I. Graham, H. Masayasu, and I.M. Macrae Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral occlusion Br. J. Pharmacol. 122 1997 1251 1256
-
(1997)
Br. J. Pharmacol.
, vol.122
, pp. 1251-1256
-
-
Takasago, T.1
Peters, E.E.2
Graham, D.I.3
Masayasu, H.4
MacRae, I.M.5
-
86
-
-
33044485049
-
Ebselen reduces cerebral lesions and improves neurological recovery after focal cerebral ischemia-reperfusion in rats (abstract)
-
V. Mary, S. Moussaoui, A. Imperato, and J.-M. Stutzmann Ebselen reduces cerebral lesions and improves neurological recovery after focal cerebral ischemia-reperfusion in rats (abstract) J. Cereb. Blood Flow Metab. 19 1999 S181
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 181
-
-
Mary, V.1
Moussaoui, S.2
Imperato, A.3
Stutzmann, J.-M.4
-
87
-
-
3042621435
-
Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia
-
J.B. Salom, F.J. Perez-Asensio, M.C. Burguete, N. Marin, C. Pitarch, G. Torregrosa, F.J. Romero, and E. Alborch Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia Eur. J. Pharmacol. 495 2004 55 62
-
(2004)
Eur. J. Pharmacol.
, vol.495
, pp. 55-62
-
-
Salom, J.B.1
Perez-Asensio, F.J.2
Burguete, M.C.3
Marin, N.4
Pitarch, C.5
Torregrosa, G.6
Romero, F.J.7
Alborch, E.8
-
88
-
-
0029114721
-
Molecular actions of ebselen-an antiinflammatory antioxidant
-
T. Schewe Molecular actions of ebselen-an antiinflammatory antioxidant Gen. Pharmacol. 26 1995 1153 1169
-
(1995)
Gen. Pharmacol.
, vol.26
, pp. 1153-1169
-
-
Schewe, T.1
-
89
-
-
3242892582
-
Neuroprotective efficacy and therapeutic time window of peroxynitrite decomposition catalysts in focal cerebral ischemia in rats
-
M. Thiyagarajan, C.L. Kaul, and S.S. Sharma Neuroprotective efficacy and therapeutic time window of peroxynitrite decomposition catalysts in focal cerebral ischemia in rats Br. J. Pharmacol. 142 2004 899 911
-
(2004)
Br. J. Pharmacol.
, vol.142
, pp. 899-911
-
-
Thiyagarajan, M.1
Kaul, C.L.2
Sharma, S.S.3
-
90
-
-
0026345023
-
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase
-
H. Kinouchi, C.J. Epstein, T. Mizui, E.J. Carlson, S.F. Chen, and P.H. Chan Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase Proc. Natl. Acad. Sci. USA 88 1991 11158 11162
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 11158-11162
-
-
Kinouchi, H.1
Epstein, C.J.2
Mizui, T.3
Carlson, E.J.4
Chen, S.F.5
Chan, P.H.6
-
91
-
-
0027765510
-
Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia
-
P.H. Chan, H. Kamii, G. Yang, J. Gafni, C.J. Epstein, E. Carlson, and L. Reola Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia Neuroreport 5 1993 293 296
-
(1993)
Neuroreport
, vol.5
, pp. 293-296
-
-
Chan, P.H.1
Kamii, H.2
Yang, G.3
Gafni, J.4
Epstein, C.J.5
Carlson, E.6
Reola, L.7
-
92
-
-
0028040278
-
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
-
G.Y. Yang, P.H. Chan, J. Chen, E. Carlson, S.F. Chen, P. Weinstein, C.J. Epestein, and H. Kamii Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia Stroke 25 1994 165 170
-
(1994)
Stroke
, vol.25
, pp. 165-170
-
-
Yang, G.Y.1
Chan, P.H.2
Chen, J.3
Carlson, E.4
Chen, S.F.5
Weinstein, P.6
Epestein, C.J.7
Kamii, H.8
-
93
-
-
0029858401
-
Effects of nitric synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia
-
H. Kamii, S. Mikawa, K. Murakami, H. Kinouchi, T. Yoshimoto, L. Reola, E. Carlson, C.J. Epstein, and P.H. Chan Effects of nitric synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia J. Cereb. Blood Flow Metab. 16 1996 1153 1157
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 1153-1157
-
-
Kamii, H.1
Mikawa, S.2
Murakami, K.3
Kinouchi, H.4
Yoshimoto, T.5
Reola, L.6
Carlson, E.7
Epstein, C.J.8
Chan, P.H.9
-
94
-
-
0032889085
-
Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia
-
H. Sheng, R.D. Bart, T.D. Oury, R.D. Pearlstein, J.D. Crapo, and D.S. Warner Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia Neuroscience 88 1999 185 191
-
(1999)
Neuroscience
, vol.88
, pp. 185-191
-
-
Sheng, H.1
Bart, R.D.2
Oury, T.D.3
Pearlstein, R.D.4
Crapo, J.D.5
Warner, D.S.6
-
95
-
-
16944366242
-
Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia
-
T. Kondo, A. Reaume, T.T. Huang, E. Carlson, K. Murakami, S.F. Chen, E.K. Hoffman, R.W. Scott, C.J. Epstein, and P.H. Chan Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia J. Neurosci. 17 1997 4180 4189
-
(1997)
J. Neurosci.
, vol.17
, pp. 4180-4189
-
-
Kondo, T.1
Reaume, A.2
Huang, T.T.3
Carlson, E.4
Murakami, K.5
Chen, S.F.6
Hoffman, E.K.7
Scott, R.W.8
Epstein, C.J.9
Chan, P.H.10
-
96
-
-
0035910375
-
Reduction of copper, zinc-superoxide dismutase in knockout mice does not affect edema or infarction volumes and the early release of mitochondrial cytochrome c after permanent focal cerebral ischemia
-
M. Fujimura, Y. Morita-Fujimura, J.-C. Copin, T. Yoshimoto, and P.H. Chan Reduction of copper, zinc-superoxide dismutase in knockout mice does not affect edema or infarction volumes and the early release of mitochondrial cytochrome c after permanent focal cerebral ischemia Brain Res. 889 2001 208 213
-
(2001)
Brain Res.
, vol.889
, pp. 208-213
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Copin, J.-C.3
Yoshimoto, T.4
Chan, P.H.5
-
97
-
-
0033591310
-
Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse
-
H. Sheng, T.C. Brady, R.D. Pearlstein, J.D. Crapo, and D.S. Warner Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse Neurosci. Lett. 267 1999 13 16
-
(1999)
Neurosci. Lett.
, vol.267
, pp. 13-16
-
-
Sheng, H.1
Brady, T.C.2
Pearlstein, R.D.3
Crapo, J.D.4
Warner, D.S.5
-
98
-
-
0034801462
-
Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
-
P.J. Crack, J.M. Taylor, N.J. Flentjar, J. de Haan, P. Hertzog, R.C. Iannello, and I. Kola Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury J. Neurochem. 78 2001 1389 1399
-
(2001)
J. Neurochem.
, vol.78
, pp. 1389-1399
-
-
Crack, P.J.1
Taylor, J.M.2
Flentjar, N.J.3
De Haan, J.4
Hertzog, P.5
Iannello, R.C.6
Kola, I.7
-
99
-
-
0031884257
-
Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage
-
M. Weisbrot-Lefkowitz, K. Reuhl, B. Perry, P.H. Chan, M. Inouye, and O. Mirochnitchenko Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage Brain Res. Mol. Brain Res. 53 1998 333 338
-
(1998)
Brain Res. Mol. Brain Res.
, vol.53
, pp. 333-338
-
-
Weisbrot-Lefkowitz, M.1
Reuhl, K.2
Perry, B.3
Chan, P.H.4
Inouye, M.5
Mirochnitchenko, O.6
-
100
-
-
33847585491
-
Tirilazad mesylate in acute ischemic stroke. a systemic review. Tirilazad International Steering Committee
-
Tirilazad International Steering Committee Tirilazad mesylate in acute ischemic stroke. A systemic review. Tirilazad International Steering Committee Stroke 32 2000 2257 2265
-
(2000)
Stroke
, vol.32
, pp. 2257-2265
-
-
International Steering Committee, T.1
-
101
-
-
0043204506
-
A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS)
-
The RANTTAS Investigators A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS) Stroke 27 1996 1453 1458
-
(1996)
Stroke
, vol.27
, pp. 1453-1458
-
-
Ranttas Investigators, T.1
-
102
-
-
0031781078
-
High-dose tirilazad for acute stroke (RANTTAS II). RANTTAS II Investigators
-
E.C. Haley Jr. High-dose tirilazad for acute stroke (RANTTAS II). RANTTAS II Investigators Stroke 29 1998 1256 1257
-
(1998)
Stroke
, vol.29
, pp. 1256-1257
-
-
Haley Jr., E.C.1
-
103
-
-
0037039233
-
TESS Investigators; TESS II Investigators. the effect of tirilazad mesylate on infarct volume of patients with acute ischemic stroke
-
H.B. van der Worp, L.J. Kappelle, A. Algra, P.R. Bar, J.M. Orgogozo, E.B. Ringelstein, P.M. Bath, and J. van Gijn TESS Investigators; TESS II Investigators. The effect of tirilazad mesylate on infarct volume of patients with acute ischemic stroke Neurology 58 2002 133 135
-
(2002)
Neurology
, vol.58
, pp. 133-135
-
-
Van Der Worp, H.B.1
Kappelle, L.J.2
Algra, A.3
Bar, P.R.4
Orgogozo, J.M.5
Ringelstein, E.B.6
Bath, P.M.7
Van Gijn, J.8
-
104
-
-
0031963836
-
Ebselen in acute ischemic stroke. a placebo-controlled, double-blind clinical trial
-
T. Yamaguchi, K. Sano, K. Takakura, I. Saito, Y. Shinohara, T. Asano, and H. Yasuhara Ebselen in acute ischemic stroke. A placebo-controlled, double-blind clinical trial Stroke 29 1998 12 17
-
(1998)
Stroke
, vol.29
, pp. 12-17
-
-
Yamaguchi, T.1
Sano, K.2
Takakura, K.3
Saito, I.4
Shinohara, Y.5
Asano, T.6
Yasuhara, H.7
-
105
-
-
0033042957
-
Ebselen in acute middle cerebral artery occlusion: A placebo-controlled, double-blind clinical trial
-
A. Ogawa, T. Yoshimoto, H. Kikuchi, K. Sano, I. Saito, T. Yamaguchi, and H. Yasuhara Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial Cerebrovasc. Dis. 9 1999 112 118
-
(1999)
Cerebrovasc. Dis.
, vol.9
, pp. 112-118
-
-
Ogawa, A.1
Yoshimoto, T.2
Kikuchi, H.3
Sano, K.4
Saito, I.5
Yamaguchi, T.6
Yasuhara, H.7
-
106
-
-
0037229213
-
Effect of a novel free radical scavenger, Edaravone (MCI-186), on acute brain infarction, placebo-controlled, double-blind study at multicenters
-
The Edaravone Acute Brain Infarction Study Group
-
The Edaravone Acute Brain Infarction Study Group Effect of a novel free radical scavenger, Edaravone (MCI-186), on acute brain infarction, placebo-controlled, double-blind study at multicenters Cerebrovasc. Dis. 15 2003 222 229
-
(2003)
Cerebrovasc. Dis.
, vol.15
, pp. 222-229
-
-
-
107
-
-
2642551352
-
Free radical scavenger, Edaravone, in stroke with internal carotid artery occlusion
-
K. Toyoda, K. Fujii, M. Kamouchi, H. Nakane, S. Arihiro, Y. Okada, S. Ibayashi, and M. Iida Free radical scavenger, Edaravone, in stroke with internal carotid artery occlusion J. Neurol. Sci. 221 2004 11 17
-
(2004)
J. Neurol. Sci.
, vol.221
, pp. 11-17
-
-
Toyoda, K.1
Fujii, K.2
Kamouchi, M.3
Nakane, H.4
Arihiro, S.5
Okada, Y.6
Ibayashi, S.7
Iida, M.8
-
108
-
-
0034745231
-
Tolerability and pharmacokinetic of the nitrone NXY-059 in patients with acute stroke
-
K.R. Lees, A.K. Sharma, D. Barer, G.A. Ford, V. Kostulas, Y.-F. Cheng, and T. Odergren Tolerability and pharmacokinetic of the nitrone NXY-059 in patients with acute stroke Stroke 32 2001 675 680
-
(2001)
Stroke
, vol.32
, pp. 675-680
-
-
Lees, K.R.1
Sharma, A.K.2
Barer, D.3
Ford, G.A.4
Kostulas, V.5
Cheng, Y.-F.6
Odergren, T.7
-
109
-
-
0037319241
-
Tolerability of NXY-059 at higher target concentrations in patients with acute stroke
-
K.R. Lees, D. Barer, G.A. Ford, W. Hacke, V. Kostulas, A.K. Sharma, and T. Odergren Tolerability of NXY-059 at higher target concentrations in patients with acute stroke Stroke 34 2003 482 487
-
(2003)
Stroke
, vol.34
, pp. 482-487
-
-
Lees, K.R.1
Barer, D.2
Ford, G.A.3
Hacke, W.4
Kostulas, V.5
Sharma, A.K.6
Odergren, T.7
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