Interferon-γ directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-γ receptor and AMPA GluR1 receptor

FASEB Journal

Volumn 22, Issue 6, 2008, Pages 1797-1806

  Mizuno, Tetsuya ^a   Zhang, Guiqin ^a   Takeuchi, Hideyuki ^a   Kawanokuchi, Jun ^a   Wang, Jinyan ^a   Sonobe, Yoshifumi ^a   Jin, Shijie ^a   Takada, Naoki ^a   Komatsu, Yukio ^a   Suzumura, Akio ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Neuronal dysfunction; Proinflammatory cytokine

Indexed keywords

AMPA RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GLUTAMATE RECEPTOR 1; JANUS KINASE 1; JANUS KINASE 2; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE; STAT1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CALCIUM TRANSPORT; CONTROLLED STUDY; EMBRYO; IMMUNOPRECIPITATION; MOUSE; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; INTERFERON TYPE II; MICE; MULTIPROTEIN COMPLEXES; NEURONS; NEUROTOXICITY SYNDROMES; PHOSPHORYLATION; RECEPTORS, AMPA; RECEPTORS, INTERFERON;

EID: 44949240517     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-099499     Document Type: Article

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