-
1
-
-
84859175189
-
Structural basis of membrane bending by the N-BAR protein endophilin
-
Mim C, Cui H, Gawronski-Salerno JA, Frost A, Lyman E, Voth GA, Unger VM (2012) Structural basis of membrane bending by the N-BAR protein endophilin. Cell 149:137-145.
-
(2012)
Cell
, vol.149
, pp. 137-145
-
-
Mim, C.1
Cui, H.2
Gawronski-Salerno, J.A.3
Frost, A.4
Lyman, E.5
Voth, G.A.6
Unger, V.M.7
-
2
-
-
84867295592
-
Molecular machines governing exocytosis of synaptic vesicles
-
Jahn R, Fasshauer D (2012) Molecular machines governing exocytosis of synaptic vesicles. Nature 490: 201-207.
-
(2012)
Nature
, vol.490
, pp. 201-207
-
-
Jahn, R.1
Fasshauer, D.2
-
3
-
-
84864631153
-
Cell-penetrating peptides: Classes, origin, and current landscape
-
Milletti F (2012) Cell-penetrating peptides: classes, origin, and current landscape. Drug Discov Today 17: 850-860.
-
(2012)
Drug Discov Today
, vol.17
, pp. 850-860
-
-
Milletti, F.1
-
4
-
-
14544282377
-
Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
-
Brogden KA (2005) Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3:238-250.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 238-250
-
-
Brogden, K.A.1
-
5
-
-
77955312210
-
Amyloidogenic protein-membrane interactions: Mechanistic insight from model systems
-
Butterfield SM, Lashuel HA (2010) Amyloidogenic protein-membrane interactions: mechanistic insight from model systems. Angew Chem Int Ed Engl 49: 5628-5654.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 5628-5654
-
-
Butterfield, S.M.1
Lashuel, H.A.2
-
6
-
-
79956047746
-
A lipocentric view of peptide-induced pores
-
Fuertes G, Gimenez D, Esteban-Martin S, Sanchez-Munoz OL, Salgado J (2011) A lipocentric view of peptide-induced pores. Eur Biophys J 40:399-415.
-
(2011)
Eur Biophys J
, vol.40
, pp. 399-415
-
-
Fuertes, G.1
Gimenez, D.2
Esteban-Martin, S.3
Sanchez-Munoz, O.L.4
Salgado, J.5
-
7
-
-
77958085274
-
Describing the mechanism of antimicrobial peptide action with the interfacial activity model
-
Wimley WC (2010) Describing the mechanism of antimicrobial peptide action with the interfacial activity model. ACS Chem Biol 5:905-917.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 905-917
-
-
Wimley, W.C.1
-
8
-
-
67650325176
-
The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: Insights from type II diabetes
-
Hebda JA, Miranker AD (2009) The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes. Annu Rev Biophys 38:125-152.
-
(2009)
Annu Rev Biophys
, vol.38
, pp. 125-152
-
-
Hebda, J.A.1
Miranker, A.D.2
-
9
-
-
56049093057
-
Cell-penetrating and cell-targeting peptides in drug delivery
-
Vives E, Schmidt J, Pelegrin A (2008) Cell-penetrating and cell-targeting peptides in drug delivery. Biochim Biophys Acta 1786:126-138.
-
(2008)
Biochim Biophys Acta
, vol.1786
, pp. 126-138
-
-
Vives, E.1
Schmidt, J.2
Pelegrin, A.3
-
10
-
-
33748935159
-
LL-37, the only human member of the cathelicidin family of antimicrobial peptides
-
Durr UHN, Sudheendra US, Ramamoorthy A (2006) LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta 1758:1408-1425.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1408-1425
-
-
Durr, U.H.N.1
Sudheendra, U.S.2
Ramamoorthy, A.3
-
11
-
-
0035204427
-
A peptide carrier for the delivery of biologically active proteins into mammalian cells
-
Morris MC, Depollier J, Mery J, Heitz F, Divita G (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol 19:1173-1176.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 1173-1176
-
-
Morris, M.C.1
Depollier, J.2
Mery, J.3
Heitz, F.4
Divita, G.5
-
13
-
-
70349428302
-
Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide
-
Williamson JA, Loria JP, Miranker AD (2009) Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide. J Mol Biol 393:383-396.
-
(2009)
J Mol Biol
, vol.393
, pp. 383-396
-
-
Williamson, J.A.1
Loria, J.P.2
Miranker, A.D.3
-
14
-
-
0023875642
-
A two-dimensional NMR study of the antimicrobial peptide magainin 2
-
Marion D, Zasloff M, Bax A (1988) A two-dimensional NMR study of the antimicrobial peptide magainin 2. FEBS Lett 227:21-26.
-
(1988)
FEBS Lett
, vol.227
, pp. 21-26
-
-
Marion, D.1
Zasloff, M.2
Bax, A.3
-
15
-
-
84881022447
-
Solution NMR studies of cell-penetrating peptides in model membrane systems
-
Maler L (2012) Solution NMR studies of cell-penetrating peptides in model membrane systems. Adv Drug Delivery Rev, http://dx.doi.org/10.1016/j.addr.2012. 10. 011.
-
(2012)
Adv Drug Delivery Rev
-
-
Maler, L.1
-
16
-
-
0032717048
-
Diversity of antimicrobial peptides and their mechanisms of action
-
Epand RM, Vogel HJ (1999) Diversity of antimicrobial peptides and their mechanisms of action. Biochim Biophys Acta 1462:11-28.
-
(1999)
Biochim Biophys Acta
, vol.1462
, pp. 11-28
-
-
Epand, R.M.1
Vogel, H.J.2
-
17
-
-
58149380718
-
Structure of membrane-bound a-synuclein from site-directed spin labeling and computational refinement
-
Jao CC, Hegde BG, Chen J, Haworth IS, Langen R (2008) Structure of membrane-bound a-synuclein from site-directed spin labeling and computational refinement. Proc Natl Acad Sci USA 105:19666-19671.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19666-19671
-
-
Jao, C.C.1
Hegde, B.G.2
Chen, J.3
Haworth, I.S.4
Langen, R.5
-
18
-
-
33748950268
-
Molecular mechanism of antimicrobial peptides: The origin of cooperativity
-
Huang HW (2006) Molecular mechanism of antimicrobial peptides: the origin of cooperativity. Biochim Biophys Acta 1758:1292-1302.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1292-1302
-
-
Huang, H.W.1
-
19
-
-
80052398365
-
A-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
-
Bartels T, Choi JG, Selkoe DJ (2011) a-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 477:107-110.
-
(2011)
Nature
, vol.477
, pp. 107-110
-
-
Bartels, T.1
Choi, J.G.2
Selkoe, D.J.3
-
20
-
-
0032763732
-
Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy
-
Marassi FM, Opella SJ, Juvvadi P, Merrifield RB (1999) Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy. Biophys J 77:3152-3155.
-
(1999)
Biophys J
, vol.77
, pp. 3152-3155
-
-
Marassi, F.M.1
Opella, S.J.2
Juvvadi, P.3
Merrifield, R.B.4
-
21
-
-
47749117154
-
Structure of a-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding
-
Apostolidou M, Jayasinghe SA, Langen R (2008) Structure of a-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding. J Biol Chem 283: 17205-17210.
-
(2008)
J Biol Chem
, vol.283
, pp. 17205-17210
-
-
Apostolidou, M.1
Jayasinghe, S.A.2
Langen, R.3
-
22
-
-
84863232604
-
Molecular interactions between cell penetrating peptide Pep-1 and model cell membranes
-
Ding B, Chen Z (2012) Molecular interactions between cell penetrating peptide Pep-1 and model cell membranes. J Phys Chem B 116:2545-2552.
-
(2012)
J Phys Chem B
, vol.116
, pp. 2545-2552
-
-
Ding, B.1
Chen, Z.2
-
23
-
-
64849109238
-
A-synuclein binds large unilamellar vesicles as an extended helix
-
Trexler AJ, Rhoades E (2009) a-synuclein binds large unilamellar vesicles as an extended helix. Biochemistry 48:2304-2306.
-
(2009)
Biochemistry
, vol.48
, pp. 2304-2306
-
-
Trexler, A.J.1
Rhoades, E.2
-
24
-
-
65249185574
-
Interplay of a-synuclein binding and conformational switching probed by single-molecule fluorescence
-
Ferreon ACM, Gambin Y, Lemke EA, Deniz AA (2009) Interplay of a-synuclein binding and conformational switching probed by single-molecule fluorescence. Proc Natl Acad Sci USA 106:5645-5650.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5645-5650
-
-
Ferreon, A.C.M.1
Gambin, Y.2
Lemke, E.A.3
Deniz, A.A.4
-
25
-
-
77949897877
-
Molecular details of bax activation, oligomerization, and membrane insertion
-
Bleicken S, Classen M, Padmavathi PVL, Ishikawa T, Zeth K, Steinhoff H-J, Bordignon E (2010) Molecular details of bax activation, oligomerization, and membrane insertion. J Biol Chem 285:6636-6647.
-
(2010)
J Biol Chem
, vol.285
, pp. 6636-6647
-
-
Bleicken, S.1
Classen, M.2
Padmavathi, P.V.L.3
Ishikawa, T.4
Zeth, K.5
Steinhoff, H.-J.6
Bordignon, E.7
-
26
-
-
33747119677
-
Conserved and cooperative assembly of membrane-bound a-helical states of islet amyloid polypeptide
-
Knight JD, Hebda JA, Miranker AD (2006) Conserved and cooperative assembly of membrane-bound a-helical states of islet amyloid polypeptide. Biochemistry 45:9496-9508.
-
(2006)
Biochemistry
, vol.45
, pp. 9496-9508
-
-
Knight, J.D.1
Hebda, J.A.2
Miranker, A.D.3
-
27
-
-
0029758719
-
Conformational and functional study of magainin 2 in model membrane environments using the new approach of systematic double-D-amino acid replacement
-
Wieprecht T, Dathe M, Schumann M, Krause E, Beyermann M, Bienert M (1996) Conformational and functional study of magainin 2 in model membrane environments using the new approach of systematic double-D-amino acid replacement. Biochemistry 35: 10844-10853.
-
(1996)
Biochemistry
, vol.35
, pp. 10844-10853
-
-
Wieprecht, T.1
Dathe, M.2
Schumann, M.3
Krause, E.4
Beyermann, M.5
Bienert, M.6
-
28
-
-
77952580991
-
Secondary structure of cell-penetrating peptides controls membrane interaction and insertion
-
Eirksdottir E, Konate K, Langel U, Divita G, Deshayes S (2010) Secondary structure of cell-penetrating peptides controls membrane interaction and insertion. Biochim Biophys Acta 1798:1119-1128.
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 1119-1128
-
-
Eirksdottir, E.1
Konate, K.2
Langel, U.3
Divita, G.4
Deshayes, S.5
-
29
-
-
23044449398
-
Amyloid ion channels: A common structural link for protein-misfolding disease
-
Quist A, Doudevski L, Lin H, Azimova R, Ng D, Frangione B, Kagan B, Ghiso J, Lal R (2005) Amyloid ion channels: a common structural link for protein-misfolding disease. Proc Natl Acad Sci USA 102:10427-10432.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10427-10432
-
-
Quist, A.1
Doudevski, L.2
Lin, H.3
Azimova, R.4
Ng, D.5
Frangione, B.6
Kagan, B.7
Ghiso, J.8
Lal, R.9
-
30
-
-
77950685282
-
Simultaneous single-molecule fluorescence and conductivity studies reveal distinct classes of Ab species on lipid bilayers
-
Schauerte JA, Wong PT, Wisser KC, Ding H, Steel DG, Gafni A (2010) Simultaneous single-molecule fluorescence and conductivity studies reveal distinct classes of Ab species on lipid bilayers. Biochemistry 49: 3031-3039.
-
(2010)
Biochemistry
, vol.49
, pp. 3031-3039
-
-
Schauerte, J.A.1
Wong, P.T.2
Wisser, K.C.3
Ding, H.4
Steel, D.G.5
Gafni, A.6
-
31
-
-
84857729756
-
Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide
-
Magzoub M, Miranker AD (2012) Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide. FASEB J 26:1228-1238.
-
(2012)
FASEB J
, vol.26
, pp. 1228-1238
-
-
Magzoub, M.1
Miranker, A.D.2
-
32
-
-
0030028241
-
Neutron scattering in the plane of membranes: Structure of alamethicin pores
-
He K, Ludtke SJ, Worcester DL, Huang HW (1996) Neutron scattering in the plane of membranes: structure of alamethicin pores. Biophys J 70:2659-2666.
-
(1996)
Biophys J
, vol.70
, pp. 2659-2666
-
-
He, K.1
Ludtke, S.J.2
Worcester, D.L.3
Huang, H.W.4
-
33
-
-
43649098591
-
Structure of the alamethicin pore reconstructed by x-ray diffraction analysis
-
Qian S, Wang W, Yang L, Huang HW (2008) Structure of the alamethicin pore reconstructed by x-ray diffraction analysis. Biophys J 94:3512-3522.
-
(2008)
Biophys J
, vol.94
, pp. 3512-3522
-
-
Qian, S.1
Wang, W.2
Yang, L.3
Huang, H.W.4
-
34
-
-
80855144832
-
A membrane-bound antiparallel dimer of rat islet amyloid polypeptide
-
Nath A, Miranker AD, Rhoades E (2011) A membrane-bound antiparallel dimer of rat islet amyloid polypeptide. Angew Chem Int Ed 50:10859-10862.
-
(2011)
Angew Chem Int Ed
, vol.50
, pp. 10859-10862
-
-
Nath, A.1
Miranker, A.D.2
Rhoades, E.3
-
35
-
-
79959342196
-
Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity
-
Last NB, Rhoades E, Miranker AD (2011) Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proc Natl Acad Sci USA 108:9460-9465.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9460-9465
-
-
Last, N.B.1
Rhoades, E.2
Miranker, A.D.3
-
36
-
-
40149107726
-
A quantitative model for the allor-none permeabilization of phospholipid vesicles by the antimicrobial peptide cecropin A
-
Gregory SM, Cavenaugh A, Journigan V, Pokorny A, Almeida PFF (2008) A quantitative model for the allor-none permeabilization of phospholipid vesicles by the antimicrobial peptide cecropin A. Biophys J 94: 1667-1680.
-
(2008)
Biophys J
, vol.94
, pp. 1667-1680
-
-
Gregory, S.M.1
Cavenaugh, A.2
Journigan, V.3
Pokorny, A.4
Almeida, P.F.F.5
-
37
-
-
34047238809
-
Mechanism of the cell-penetrating peptide transportan 10 permeation of lipid bilayers
-
Yandek LE, Pokorny A, Floren A, Knoelke K, Langel U, Almeida PFF (2007) Mechanism of the cell-penetrating peptide transportan 10 permeation of lipid bilayers. Biophys J 92:2434-2444.
-
(2007)
Biophys J
, vol.92
, pp. 2434-2444
-
-
Yandek, L.E.1
Pokorny, A.2
Floren, A.3
Knoelke, K.4
Langel, U.5
Almeida, P.F.F.6
-
38
-
-
0035159553
-
Amyloid b protein forms ion channels: Implications for Alzheimer's disease pathophysiology
-
Lin H, Bhatia R, Lal R (2001) Amyloid b protein forms ion channels: implications for Alzheimer's disease pathophysiology. FASEB J 15:2433-2444.
-
(2001)
FASEB J
, vol.15
, pp. 2433-2444
-
-
Lin, H.1
Bhatia, R.2
Lal, R.3
-
39
-
-
0030044018
-
Pore formation by the cytotoxic islet amyloid peptide amylin
-
Mirzabekov TA, Lin M-C, Kagan BL (1996) Pore formation by the cytotoxic islet amyloid peptide amylin. J Biol Chem 271:1988-1992.
-
(1996)
J Biol Chem
, vol.271
, pp. 1988-1992
-
-
Mirzabekov, T.A.1
Lin, M.-C.2
Kagan, B.L.3
-
40
-
-
0032774790
-
Membrane channel formation by antimicrobial protegrins
-
Sokolov Y, Mirzabekov T, Martin DW, Lehrer RI, Kagan BL (1999) Membrane channel formation by antimicrobial protegrins. Biochim Biophys Acta 1420: 23-29.
-
(1999)
Biochim Biophys Acta
, vol.1420
, pp. 23-29
-
-
Sokolov, Y.1
Mirzabekov, T.2
Martin, D.W.3
Lehrer, R.I.4
Kagan, B.L.5
-
41
-
-
77952960621
-
Antimicrobial protegrin-1 forms ion channels: Molecular dynamic simulation, atomic force microscopy, and electrical conductance studies
-
Capone R, Mustata M, Jang H, Arce FT, Nussinov R, Lal R (2010) Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies. Biophys J 98:2644-2652.
-
(2010)
Biophys J
, vol.98
, pp. 2644-2652
-
-
Capone, R.1
Mustata, M.2
Jang, H.3
Arce, F.T.4
Nussinov, R.5
Lal, R.6
-
42
-
-
57049086457
-
A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity
-
Brender JR, Hartman K, Reid KR, Kennedy RT, Ramamoorthy A (2008) A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry 47:12680-12688.
-
(2008)
Biochemistry
, vol.47
, pp. 12680-12688
-
-
Brender, J.R.1
Hartman, K.2
Reid, K.R.3
Kennedy, R.T.4
Ramamoorthy, A.5
-
43
-
-
79959945013
-
Astrocytes are important mediators of Ab-induced neurotoxicity and tau phosphorylation in primary culture
-
Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W (2011) Astrocytes are important mediators of Ab-induced neurotoxicity and tau phosphorylation in primary culture. Cell Death Dis 2:e167.
-
(2011)
Cell Death Dis
, vol.2
-
-
Garwood, C.J.1
Pooler, A.M.2
Atherton, J.3
Hanger, D.P.4
Noble, W.5
-
44
-
-
77949394595
-
Active fragments from pro-and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence
-
Guillemin Y, Lopez J, Gimenez D, Fuertes G, Valero JG, Blum L, Gonzalo P, Salgado J, Girard-Egrot A, Aouacheria A (2010) Active fragments from pro-and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence. PLoS One 5:e9066.
-
(2010)
PLoS One
, vol.5
-
-
Guillemin, Y.1
Lopez, J.2
Gimenez, D.3
Fuertes, G.4
Valero, J.G.5
Blum, L.6
Gonzalo, P.7
Salgado, J.8
Girard-Egrot, A.9
Aouacheria, A.10
-
45
-
-
0001408455
-
Histones and basic polyamino acids stimulate the uptake of albumin by tumor cells in culture
-
Ryser HJ-P, Hancock R (1965) Histones and basic polyamino acids stimulate the uptake of albumin by tumor cells in culture. Science 150:501-503.
-
(1965)
Science
, vol.150
, pp. 501-503
-
-
Ryser, H.J.-P.1
Hancock, R.2
-
46
-
-
67649256037
-
Control of cell selectivity of antimicrobial peptides
-
Matsuzaki K (2009) Control of cell selectivity of antimicrobial peptides. Biochim Biophys Acta 1788: 1687-1692.
-
(2009)
Biochim Biophys Acta
, vol.1788
, pp. 1687-1692
-
-
Matsuzaki, K.1
-
47
-
-
0037071786
-
Conformational states of the cell-penetrating peptide penetratin when interacting with phospholipid vesicles: Effects of surface charge and peptide concentration
-
Magzoub M, Eriksson LEG, Graslund A (2002) Conformational states of the cell-penetrating peptide penetratin when interacting with phospholipid vesicles: effects of surface charge and peptide concentration. Biochim Biophys Acta 1563:53-63.
-
(2002)
Biochim Biophys Acta
, vol.1563
, pp. 53-63
-
-
Magzoub, M.1
Eriksson, L.E.G.2
Graslund, A.3
-
48
-
-
20944447518
-
Cell-penetrating peptides: Small from inception to application
-
Magzoub M, Graslund A (2004) Cell-penetrating peptides: small from inception to application. Q Rev Biophys 37:147-195.
-
(2004)
Q Rev Biophys
, vol.37
, pp. 147-195
-
-
Magzoub, M.1
Graslund, A.2
-
49
-
-
0028100179
-
Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells
-
Rustenbeck I, Matthies A, Lenzen S (1994) Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells. Lipids 29:685-692.
-
(1994)
Lipids
, vol.29
, pp. 685-692
-
-
Rustenbeck, I.1
Matthies, A.2
Lenzen, S.3
-
50
-
-
0031825554
-
From the globular to the fibrous state: Protein structure and structural conversion in amyloid formation
-
Sunde M, Blake CC (1998) From the globular to the fibrous state: protein structure and structural conversion in amyloid formation. Q Rev Biophys 31:1-39.
-
(1998)
Q Rev Biophys
, vol.31
, pp. 1-39
-
-
Sunde, M.1
Blake, C.C.2
-
52
-
-
67650809307
-
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules
-
Maji SK, Perrin MH, Sawaya MR, Jessberger S, Vadodaria K, Rissman RA, Singru PS, Nilsson KPR, Simon R, Schubert D, Eisenberg D, Rivier J, Sawchenko P, Vale W, Riek R (2009) Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science 325:328-332..
-
(2009)
Science
, vol.325
, pp. 328-332
-
-
Maji, S.K.1
Perrin, M.H.2
Sawaya, M.R.3
Jessberger, S.4
Vadodaria, K.5
Rissman, R.A.6
Singru, P.S.7
Nilsson, K.P.R.8
Simon, R.9
Schubert, D.10
Eisenberg, D.11
Rivier, J.12
Sawchenko, P.13
Vale, W.14
Riek, R.15
-
53
-
-
0032590054
-
Soluble pool of Ab amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL (1999) Soluble pool of Ab amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 46:860-866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
54
-
-
0033048453
-
The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles
-
Janson J, Ashley RH, Harrison D, McIntyre S, Butler PC (1999) The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles. Diabetes 48:491-498.
-
(1999)
Diabetes
, vol.48
, pp. 491-498
-
-
Janson, J.1
Ashley, R.H.2
Harrison, D.3
McIntyre, S.4
Butler, P.C.5
-
55
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300:486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
56
-
-
0347753786
-
Two types of Alzheimer's b-amyloid (1-40) peptide membrane interactions: Aggregation preventing transmembrane anchoring versus accelerated surface fibril formation
-
Bokvist M, Lindstrom F, Watts A, Grobner G (2004) Two types of Alzheimer's b-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. J Mol Biol 335:1039-1049.
-
(2004)
J Mol Biol
, vol.335
, pp. 1039-1049
-
-
Bokvist, M.1
Lindstrom, F.2
Watts, A.3
Grobner, G.4
-
57
-
-
0037155235
-
Cholesterol is an important factor affecting the membrane insertion of bamyloid peptide (Ab 1-40), which may potentially inhibit the fibril formation
-
Ji S-R, Wu Y, Sui S-F (2002) Cholesterol is an important factor affecting the membrane insertion of bamyloid peptide (Ab 1-40), which may potentially inhibit the fibril formation. J Biol Chem 277:6273-6279.
-
(2002)
J Biol Chem
, vol.277
, pp. 6273-6279
-
-
Ji, S.-R.1
Wu, Y.2
Sui, S.-F.3
-
58
-
-
37249003742
-
Helical a-synuclein forms highly conductive ion channels
-
Zakharov SD, Hulleman JD, Dutseva EA, Antonenko YN, Rochet J-C, Cramer WA (2007) Helical a-synuclein forms highly conductive ion channels. Biochemistry 46:14369-14379.
-
(2007)
Biochemistry
, vol.46
, pp. 14369-14379
-
-
Zakharov, S.D.1
Hulleman, J.D.2
Dutseva, E.A.3
Antonenko, Y.N.4
Rochet, J.-C.5
Cramer, W.A.6
-
59
-
-
4143094106
-
Phospholipid catalysis of diabetic amyloid assembly
-
Knight JD, Miranker AD (2004) Phospholipid catalysis of diabetic amyloid assembly. J Mol Biol 341: 1175-1187.
-
(2004)
J Mol Biol
, vol.341
, pp. 1175-1187
-
-
Knight, J.D.1
Miranker, A.D.2
-
60
-
-
79953850289
-
Specificity and kinetics of a-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe
-
Shvadchak VV, Falomir-Lockhart LJ, Yushchenko DA, Jovin TM (2011) Specificity and kinetics of a-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe. J Biol Chem 286:13023-13032.
-
(2011)
J Biol Chem
, vol.286
, pp. 13023-13032
-
-
Shvadchak, V.V.1
Falomir-Lockhart, L.J.2
Yushchenko, D.A.3
Jovin, T.M.4
-
61
-
-
0342378042
-
Interaction of Alzheimer b-amyloid peptide(1-40) with lipid membranes
-
Terzi E, Holzemann G, Seelig J (1997) Interaction of Alzheimer b-amyloid peptide(1-40) with lipid membranes. Biochemistry 36:14845-14852.
-
(1997)
Biochemistry
, vol.36
, pp. 14845-14852
-
-
Terzi, E.1
Holzemann, G.2
Seelig, J.3
-
62
-
-
67249117859
-
A-helix targeting reduces amyloid-b peptide toxicity
-
Nerelius C, Sandegren A, Sargsyan H, Raunak R, Leijonmarck H, Chatterjee U, Fisahn A, Imarisio S, Lomas DA, Crowther DC, Stromberg R, Johansson J (2009) a-helix targeting reduces amyloid-b peptide toxicity. Proc Natl Acad Sci USA 106:9191-9196.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9191-9196
-
-
Nerelius, C.1
Sandegren, A.2
Sargsyan, H.3
Raunak, R.4
Leijonmarck, H.5
Chatterjee, U.6
Fisahn, A.7
Imarisio, S.8
Lomas, D.A.9
Crowther, D.C.10
Stromberg, R.11
Johansson, J.12
-
63
-
-
70349165341
-
A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes
-
Hebda JA, Saraogi I, Magzoub M, Hamilton AD, Miranker AD (2009) A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes. Chem Biol 16:943-950.
-
(2009)
Chem Biol
, vol.16
, pp. 943-950
-
-
Hebda, J.A.1
Saraogi, I.2
Magzoub, M.3
Hamilton, A.D.4
Miranker, A.D.5
-
64
-
-
84863229747
-
Atomic view of a toxic amyloid small oligomer
-
Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D (2012) Atomic view of a toxic amyloid small oligomer. Science 335:1228-1231.
-
(2012)
Science
, vol.335
, pp. 1228-1231
-
-
Laganowsky, A.1
Liu, C.2
Sawaya, M.R.3
Whitelegge, J.P.4
Park, J.5
Zhao, M.6
Pensalfini, A.7
Soriaga, A.B.8
Landau, M.9
Teng, P.K.10
Cascio, D.11
Glabe, C.12
Eisenberg, D.13
-
65
-
-
66249127141
-
Sorting of lipids and proteins in membrane curvature gradients
-
Tian A, Baumgart T (2009) Sorting of lipids and proteins in membrane curvature gradients. Biophys J 96: 2676-2688.
-
(2009)
Biophys J
, vol.96
, pp. 2676-2688
-
-
Tian, A.1
Baumgart, T.2
-
66
-
-
67749097800
-
Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: The case of islet amyloid polypeptide
-
Smith PES, Brender JR, Ramamoorthy A (2009) Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide. J Am Chem Soc 131: 4470-4478.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 4470-4478
-
-
Smith, P.E.S.1
Brender, J.R.2
Ramamoorthy, A.3
-
67
-
-
0033616779
-
Interactions of amyloid b-peptide (1-40) with ganglioside-containing membranes
-
Matsuzaki K, Horikiri C (1999) Interactions of amyloid b-peptide (1-40) with ganglioside-containing membranes. Biochemistry 38:4137-4142.
-
(1999)
Biochemistry
, vol.38
, pp. 4137-4142
-
-
Matsuzaki, K.1
Horikiri, C.2
-
68
-
-
77958455514
-
Effects of curvature and composition on a-synuclein binding to lipid vesicles
-
Middleton ER, Rhoades E (2010) Effects of curvature and composition on a-synuclein binding to lipid vesicles. Biophys J 99:2279-2288.
-
(2010)
Biophys J
, vol.99
, pp. 2279-2288
-
-
Middleton, E.R.1
Rhoades, E.2
-
69
-
-
84876219852
-
Common mechanism unites membrane poration by amyloid and antimicrobial peptides
-
Last NB, Miranker AD (2013) Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci USA 110: 6382-6387.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6382-6387
-
-
Last, N.B.1
Miranker, A.D.2
-
70
-
-
77949830350
-
The Alzheimer's disease-associated amyloid b-protein is an antimicrobial peptide
-
Soscia SJ, Kirby JE, Washicosky KJ, Tucker SM, Ingelsson M, Hyman B, Burton MA, Goldstein LE, Duong S, Tanzi RE, Moir RD (2010) The Alzheimer's disease-associated amyloid b-protein is an antimicrobial peptide. PLoS One 5:e9505.
-
(2010)
PLoS One
, vol.5
-
-
Soscia, S.J.1
Kirby, J.E.2
Washicosky, K.J.3
Tucker, S.M.4
Ingelsson, M.5
Hyman, B.6
Burton, M.A.7
Goldstein, L.E.8
Duong, S.9
Tanzi, R.E.10
Moir, R.D.11
-
71
-
-
84867816810
-
Antimicrobial activity of human islet amyloid polypeptides: An insight into amyloid peptides' connection with antimicrobial peptides
-
Wang L, Liu Q, Chen J-C, Cui Y-X, Zhou B, Chen YX, Zhao Y-F, Li Y-M (2012) Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides. Biol Chem 393:641-646.
-
(2012)
Biol Chem
, vol.393
, pp. 641-646
-
-
Wang, L.1
Liu, Q.2
Chen, J.-C.3
Cui, Y.-X.4
Zhou, B.5
Chen, Y.X.6
Zhao, Y.-F.7
Li, Y.-M.8
-
72
-
-
0037165196
-
Antimicrobial peptides of multicellular organisms
-
Zasloff M (2002) Antimicrobial peptides of multicellular organisms. Nature 415:389-395.
-
(2002)
Nature
, vol.415
, pp. 389-395
-
-
Zasloff, M.1
-
73
-
-
84856864352
-
Antimicrobial peptides: Old molecules with new ideas
-
Nakatsuji T, Gallo RL (2011) Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol 132: 887-895.
-
(2011)
J Invest Dermatol
, vol.132
, pp. 887-895
-
-
Nakatsuji, T.1
Gallo, R.L.2
-
74
-
-
80051785173
-
The expanding scope of antimicrobial peptide structures and their modes of action
-
Nguyen LT, Haney EF, Vogel HJ (2011) The expanding scope of antimicrobial peptide structures and their modes of action. Trends Biotechnol 29:464-472.
-
(2011)
Trends Biotechnol
, vol.29
, pp. 464-472
-
-
Nguyen, L.T.1
Haney, E.F.2
Vogel, H.J.3
-
75
-
-
0030981655
-
Structure and functions of channel-forming peptides: Magainins, cecropins, melittin and alamethicin
-
Bechinger B (1997) Structure and functions of channel-forming peptides: magainins, cecropins, melittin and alamethicin. J Membr Biol 156:197-211.
-
(1997)
J Membr Biol
, vol.156
, pp. 197-211
-
-
Bechinger, B.1
-
76
-
-
79953790729
-
Bacterial membrane lipids in the action of antimicrobial agents
-
Epand RM, Epand RF (2010) Bacterial membrane lipids in the action of antimicrobial agents. J Peptide Sci 17:298-305.
-
(2010)
J Peptide Sci
, vol.17
, pp. 298-305
-
-
Epand, R.M.1
Epand, R.F.2
-
77
-
-
33748933561
-
Alpha-helical antimicrobial peptides-using a sequence template to guide structure-activity relationship studies
-
Zelezetsky I, Tossi A (2006) Alpha-helical antimicrobial peptides-using a sequence template to guide structure-activity relationship studies. Biochim Biophys Acta 1758:1436-1449.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1436-1449
-
-
Zelezetsky, I.1
Tossi, A.2
-
78
-
-
0035919725
-
Optimization of the antimicrobial activity of magainin peptides by modification of charge
-
Dathe M, Nikolenko H, Meyer J, Beyermann M, Bienert M (2001) Optimization of the antimicrobial activity of magainin peptides by modification of charge. FEBS Lett 501:146-150.
-
(2001)
FEBS Lett
, vol.501
, pp. 146-150
-
-
Dathe, M.1
Nikolenko, H.2
Meyer, J.3
Beyermann, M.4
Bienert, M.5
-
79
-
-
34247153326
-
Role of peptide hydrophobicity in the mechanism of action of a-helical antimicrobial peptides
-
Chen Y, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS (2007) Role of peptide hydrophobicity in the mechanism of action of a-helical antimicrobial peptides. Antimicrob Agents Chemother 51:1398-1406.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1398-1406
-
-
Chen, Y.1
Guarnieri, M.T.2
Vasil, A.I.3
Vasil, M.L.4
Mant, C.T.5
Hodges, R.S.6
-
80
-
-
84863230302
-
Roles of hydrophobicity and charge distribution of cationic antimicrobial peptides in peptide-membrane interactions
-
Yin LM, Edwards MA, Li J, Yip CM, Deber CM (2012) Roles of hydrophobicity and charge distribution of cationic antimicrobial peptides in peptide-membrane interactions. J Biol Chem 287:7738-7745.
-
(2012)
J Biol Chem
, vol.287
, pp. 7738-7745
-
-
Yin, L.M.1
Edwards, M.A.2
Li, J.3
Yip, C.M.4
Deber, C.M.5
-
81
-
-
16844373772
-
Rational design of a-helical antimicrobial peptides with enhanced activities and specificity/ therapeutic index
-
Chen Y, Mant CT, Farmer SW, Hancock REW, Vasil ML, Hodges RS (2005) Rational design of a-helical antimicrobial peptides with enhanced activities and specificity/ therapeutic index. J Biol Chem 280:12316-12329.
-
(2005)
J Biol Chem
, vol.280
, pp. 12316-12329
-
-
Chen, Y.1
Mant, C.T.2
Farmer, S.W.3
Hancock, R.E.W.4
Vasil, M.L.5
Hodges, R.S.6
-
82
-
-
70350435548
-
Multifunctional host defense peptides: Intracellular-targeting antimicrobial peptides
-
Nicolas P (2009) Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides. FEBS J 276:6483-6496.
-
(2009)
FEBS J
, vol.276
, pp. 6483-6496
-
-
Nicolas, P.1
-
83
-
-
0029111532
-
Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles
-
Gazit E, Boman A, Boman HG, Shai Y (1995) Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry 34: 11479-11488.
-
(1995)
Biochemistry
, vol.34
, pp. 11479-11488
-
-
Gazit, E.1
Boman, A.2
Boman, H.G.3
Shai, Y.4
-
84
-
-
0026969265
-
Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes
-
Pouny Y, Rapaport D, Mor A, Nicolas P, Shai Y (1992) Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes. Biochemistry 31:12416-12423.
-
(1992)
Biochemistry
, vol.31
, pp. 12416-12423
-
-
Pouny, Y.1
Rapaport, D.2
Mor, A.3
Nicolas, P.4
Shai, Y.5
-
85
-
-
0029904095
-
Membrane pores induced by magainin
-
Ludtke SJ, He K, Heller WT, Harroun TA, Yang L, Huang HW (1996) Membrane pores induced by magainin. Biochemistry 35:13723-13728.
-
(1996)
Biochemistry
, vol.35
, pp. 13723-13728
-
-
Ludtke, S.J.1
He, K.2
Heller, W.T.3
Harroun, T.A.4
Yang, L.5
Huang, H.W.6
-
86
-
-
0037031254
-
Solid-state NMR investigations of peptide-lipid interaction and orientation of a beta-sheet antimicrobial peptide, protegrin
-
Yamaguchi S, Hong T, Waring A, Lehrer RI, Hong M (2002) Solid-state NMR investigations of peptide-lipid interaction and orientation of a beta-sheet antimicrobial peptide, protegrin. Biochemistry 41:9852-9862.
-
(2002)
Biochemistry
, vol.41
, pp. 9852-9862
-
-
Yamaguchi, S.1
Hong, T.2
Waring, A.3
Lehrer, R.I.4
Hong, M.5
-
87
-
-
84871832622
-
Direct visualization of the alamethicin pore formed in a planar phospholipid matrix
-
Pieta P, Mirza J, Lipkowski J (2012) Direct visualization of the alamethicin pore formed in a planar phospholipid matrix. Proc Natl Acad Sci USA 109: 21223-21227.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 21223-21227
-
-
Pieta, P.1
Mirza, J.2
Lipkowski, J.3
-
88
-
-
58849140539
-
Magainin 2 revisited: A test of the quantitative model for the all-or-none permeabilization of phospholipid vesicles
-
Gregory SM, Pokorny A, Almeida PFF (2009) Magainin 2 revisited: a test of the quantitative model for the all-or-none permeabilization of phospholipid vesicles. Biophys J 96:116-131.
-
(2009)
Biophys J
, vol.96
, pp. 116-131
-
-
Gregory, S.M.1
Pokorny, A.2
Almeida, P.F.F.3
-
89
-
-
1642359643
-
Energetics of pore formation induced by membrane active peptides
-
Lee M-T, Chen F-Y, Huang HW (2004) Energetics of pore formation induced by membrane active peptides. Biochemistry 43:3590-3599.
-
(2004)
Biochemistry
, vol.43
, pp. 3590-3599
-
-
Lee, M.-T.1
Chen, F.-Y.2
Huang, H.W.3
-
90
-
-
0034023711
-
Conformation and dynamics of melittin bound to magnetically oriented lipid bilayers by solidstate (31)P and (13)C NMR spectroscopy
-
Naito A, Nagao T, Norisada K, Mizuno T, Tuzi S, Saito H (2000) Conformation and dynamics of melittin bound to magnetically oriented lipid bilayers by solidstate (31)P and (13)C NMR spectroscopy. Biophys J 78:2405-2417.
-
(2000)
Biophys J
, vol.78
, pp. 2405-2417
-
-
Naito, A.1
Nagao, T.2
Norisada, K.3
Mizuno, T.4
Tuzi, S.5
Saito, H.6
-
91
-
-
0035479424
-
Detergent-like' permeabilization of anionic lipid vesicles by melittin
-
Ladokhin AS, White SH (2001) 'Detergent-like' permeabilization of anionic lipid vesicles by melittin. Biochem Biophys Acta 1514:253-260.
-
(2001)
Biochem Biophys Acta
, vol.1514
, pp. 253-260
-
-
Ladokhin, A.S.1
White, S.H.2
-
92
-
-
0022798958
-
The structure of melittin in membranes
-
Vogel H, Jahnig F (1986) The structure of melittin in membranes. Biophys J 50:573-582.
-
(1986)
Biophys J
, vol.50
, pp. 573-582
-
-
Vogel, H.1
Jahnig, F.2
-
93
-
-
84859882976
-
Determining the mechanism of membrane permeabilizing peptides: Identification of potent, equilibrium pore-formers
-
Krauson AJ, He J, Wimley WC (2012) Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta 1818:1625-1632.
-
(2012)
Biochim Biophys Acta
, vol.1818
, pp. 1625-1632
-
-
Krauson, A.J.1
He, J.2
Wimley, W.C.3
-
94
-
-
0021343526
-
Insertion of apocytochrome c into lipid vesicles
-
Dumont ME, Richards FM (1984) Insertion of apocytochrome c into lipid vesicles. J Biol Chem 259: 4147-4156.
-
(1984)
J Biol Chem
, vol.259
, pp. 4147-4156
-
-
Dumont, M.E.1
Richards, F.M.2
-
95
-
-
82755194760
-
Protein transduction domain delivery of therapeutic macromolecules
-
van den Berg A, Dowdy SF (2011) Protein transduction domain delivery of therapeutic macromolecules. Curr Opin Biotechnol 22:888-893.
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 888-893
-
-
Van Den Berg, A.1
Dowdy, S.F.2
-
96
-
-
65449148821
-
Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins
-
McNaughton BR, Cronican JJ, Thompson DB, Liu DR (2009) Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins. Proc Natl Acad Sci USA 106:6111-6116.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6111-6116
-
-
McNaughton, B.R.1
Cronican, J.J.2
Thompson, D.B.3
Liu, D.R.4
-
97
-
-
77749233798
-
PH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path
-
Andreev OA, Karabadzhak AG, Weerakkody D, Andreev GO, Engelman DM, Reshetnyak YK (2010) pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path. Proc Natl Acad Sci USA 107:4081-4086.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4081-4086
-
-
Andreev, O.A.1
Karabadzhak, A.G.2
Weerakkody, D.3
Andreev, G.O.4
Engelman, D.M.5
Reshetnyak, Y.K.6
-
98
-
-
79958796013
-
Spontaneous membrane-translocating peptides by orthogonal high-throughput screening
-
Marks JR, Placone J, Hristova K, Wimley WC (2011) Spontaneous membrane-translocating peptides by orthogonal high-throughput screening. J Am Chem Soc 133:8995-9004.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 8995-9004
-
-
Marks, J.R.1
Placone, J.2
Hristova, K.3
Wimley, W.C.4
-
99
-
-
79956025776
-
Antimicrobial peptides with cell-penetrating peptide properties and vice versa
-
Splith K, Neundorf I (2011) Antimicrobial peptides with cell-penetrating peptide properties and vice versa. Eur Biophys J 40:387-397.
-
(2011)
Eur Biophys J
, vol.40
, pp. 387-397
-
-
Splith, K.1
Neundorf, I.2
-
100
-
-
2342520028
-
The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis
-
Sandgren S, Wittrup A, Cheng F, Jonsson M, Eklund E, Busch S, Belting M (2004) The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis. J Biol Chem 279:17951-17956.
-
(2004)
J Biol Chem
, vol.279
, pp. 17951-17956
-
-
Sandgren, S.1
Wittrup, A.2
Cheng, F.3
Jonsson, M.4
Eklund, E.5
Busch, S.6
Belting, M.7
-
101
-
-
0036712127
-
Mechanism and kinetics of d-lysin interaction with phospholipid vesicles
-
Pokorny A, Birkbeck TH, Almeida PFF (2002) Mechanism and kinetics of d-lysin interaction with phospholipid vesicles. Biochemistry 41:11044-11056.
-
(2002)
Biochemistry
, vol.41
, pp. 11044-11056
-
-
Pokorny, A.1
Birkbeck, T.H.2
Almeida, P.F.F.3
-
102
-
-
0037167613
-
Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes
-
Anguiano M, Nowak RJ, Lansbury PT Jr (2002) Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes. Biochemistry 41: 11338-11343.
-
(2002)
Biochemistry
, vol.41
, pp. 11338-11343
-
-
Anguiano, M.1
Nowak, R.J.2
Lansbury Jr., P.T.3
-
103
-
-
0032717886
-
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by a-helical antimicrobial and cell non-selective membrane-lytic peptides
-
Shai Y (1999) Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by a-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta 1462:55-70.
-
(1999)
Biochim Biophys Acta
, vol.1462
, pp. 55-70
-
-
Shai, Y.1
-
104
-
-
0032693639
-
Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes
-
Matsuzaki K (1999) Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim Biophys Acta 1462:1-10.
-
(1999)
Biochim Biophys Acta
, vol.1462
, pp. 1-10
-
-
Matsuzaki, K.1
-
105
-
-
0034713831
-
Action of antimicrobial peptides: Two-state model
-
Huang HW (2000) Action of antimicrobial peptides: two-state model. Biochemistry 39:8347-8352.
-
(2000)
Biochemistry
, vol.39
, pp. 8347-8352
-
-
Huang, H.W.1
-
106
-
-
2942754299
-
Molecular mechanism of peptide-induced pores in membranes
-
Huang HW, Chen F-Y, Lee M-T (2004) Molecular mechanism of peptide-induced pores in membranes. Phys Rev Lett 92:198304.
-
(2004)
Phys Rev Lett
, vol.92
, pp. 198304
-
-
Huang, H.W.1
Chen, F.-Y.2
Lee, M.-T.3
-
107
-
-
0038778549
-
Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation
-
Chen F-Y, Lee M-T, Huang HW (2003) Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation. Biophys J 84:3751-3758.
-
(2003)
Biophys J
, vol.84
, pp. 3751-3758
-
-
Chen, F.-Y.1
Lee, M.-T.2
Huang, H.W.3
-
108
-
-
0034910318
-
Osmotically induced membrane tension modulates membrane permeabilization by class L amphipathic helical peptides: Nucleation model of defect formation
-
Polozov IV, Anantharamaiah GM, Segrest JP, Epand RM (2001) Osmotically induced membrane tension modulates membrane permeabilization by class L amphipathic helical peptides: nucleation model of defect formation. Biophys J 81:949-959.
-
(2001)
Biophys J
, vol.81
, pp. 949-959
-
-
Polozov, I.V.1
Anantharamaiah, G.M.2
Segrest, J.P.3
Epand, R.M.4
-
109
-
-
0000624449
-
Stability of lipid bilayers and red blood cell membranes
-
Litster JD (1975) Stability of lipid bilayers and red blood cell membranes. Phys Lett A 53:193-194.
-
(1975)
Phys Lett A
, vol.53
, pp. 193-194
-
-
Litster, J.D.1
-
110
-
-
0016817648
-
Osmotic pressure induced pores in phospholipid vesicles
-
Taupin C, Dvolaitzky M, Sauterey C (1975) Osmotic pressure induced pores in phospholipid vesicles. Biochemistry 14:4771-4775.
-
(1975)
Biochemistry
, vol.14
, pp. 4771-4775
-
-
Taupin, C.1
Dvolaitzky, M.2
Sauterey, C.3
-
112
-
-
0032566283
-
Relationship of membrane curvature to the formation of pores by magainin 2
-
Matsuzaki K, Sugishita K, Ishibe N, Ueha M, Nakata S, Miyajima K, Epand RM (1998) Relationship of membrane curvature to the formation of pores by magainin 2. Biochemistry 37:11856-11863.
-
(1998)
Biochemistry
, vol.37
, pp. 11856-11863
-
-
Matsuzaki, K.1
Sugishita, K.2
Ishibe, N.3
Ueha, M.4
Nakata, S.5
Miyajima, K.6
Epand, R.M.7
-
113
-
-
0038052326
-
Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37
-
Henzler Wildman KA, Lee D-K, Ramamoorthy A (2003) Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37. Biochemistry 42: 6545-6558.
-
(2003)
Biochemistry
, vol.42
, pp. 6545-6558
-
-
Henzler Wildman, K.A.1
Lee, D.-K.2
Ramamoorthy, A.3
-
114
-
-
80054764378
-
Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions
-
Mishra A, Lai GH, Schmidt NW, Sun VZ, Rodriguez AR, Tong R, Tang L, Cheng J, Deming TJ, Kamei DT, Wong GCL (2011) Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions. Proc Natl Acad Sci USA 108:16883-16888.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16883-16888
-
-
Mishra, A.1
Lai, G.H.2
Schmidt, N.W.3
Sun, V.Z.4
Rodriguez, A.R.5
Tong, R.6
Tang, L.7
Cheng, J.8
Deming, T.J.9
Kamei, D.T.10
Wong, G.C.L.11
-
115
-
-
0036156880
-
Sigmoidal concentration dependence of antimicrobial peptide activities: A case study on alamethicin
-
Chen F-Y, Lee M-T, Huang HW (2002) Sigmoidal concentration dependence of antimicrobial peptide activities: a case study on alamethicin. Biophys J 82: 908-914.
-
(2002)
Biophys J
, vol.82
, pp. 908-914
-
-
Chen, F.-Y.1
Lee, M.-T.2
Huang, H.W.3
-
116
-
-
77956761543
-
Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes
-
Tamba Y, Ariyama H, Levadny V, Yamazaki M (2010) Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes. J Phys Chem B 114:12018-12026.
-
(2010)
J Phys Chem B
, vol.114
, pp. 12018-12026
-
-
Tamba, Y.1
Ariyama, H.2
Levadny, V.3
Yamazaki, M.4
-
117
-
-
78349267221
-
Pores formed by Baxa5 relax to a smaller size and keep at equilibrium
-
Fuertes G, Garcia-Saez AJ, Esteban-Martin S, Gimenez D, Sanchez-Munoz OL, Schwille P, Salgado J (2010) Pores formed by Baxa5 relax to a smaller size and keep at equilibrium. Biophys J 99:2917-2925.
-
(2010)
Biophys J
, vol.99
, pp. 2917-2925
-
-
Fuertes, G.1
Garcia-Saez, A.J.2
Esteban-Martin, S.3
Gimenez, D.4
Sanchez-Munoz, O.L.5
Schwille, P.6
Salgado, J.7
-
118
-
-
42449116949
-
Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides
-
Lee M-T, Hung W-C, Chen F-Y, Huang HW (2008) Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides. Proc Natl Acad Sci USA 105:5087-5092.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5087-5092
-
-
Lee, M.-T.1
Hung, W.-C.2
Chen, F.-Y.3
Huang, H.W.4
-
119
-
-
79959651424
-
Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link
-
Jang H, Arce FT, Mustata M, Ramachandran S, Capone R, Nussinov R, Lal R (2011) Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link. Biophys J 100:1775-1783.
-
(2011)
Biophys J
, vol.100
, pp. 1775-1783
-
-
Jang, H.1
Arce, F.T.2
Mustata, M.3
Ramachandran, S.4
Capone, R.5
Nussinov, R.6
Lal, R.7
-
120
-
-
40949128785
-
Binding of LL-37 to model biomembranes: Insight into target vs host cell recognition
-
Sood R, Domanov Y, Pietiainen M, Kontinen VP, Kinnunen PKJ (2008) Binding of LL-37 to model biomembranes: insight into target vs host cell recognition. Biochim Biophys Acta 1778:983-996.
-
(2008)
Biochim Biophys Acta
, vol.1778
, pp. 983-996
-
-
Sood, R.1
Domanov, Y.2
Pietiainen, M.3
Kontinen, V.P.4
Kinnunen, P.K.J.5
-
121
-
-
0030823756
-
Acceleration of amyloid fibril formation by specific binding of Ab-(1-40) peptide to ganglioside-containing membrane vesicles
-
Choo-Smith L-P, Garzon-Rodriguez W, Glabe CG, Surewicz WK (1997) Acceleration of amyloid fibril formation by specific binding of Ab-(1-40) peptide to ganglioside-containing membrane vesicles. J Biol Chem 272:22987-22990.
-
(1997)
J Biol Chem
, vol.272
, pp. 22987-22990
-
-
Choo-Smith, L.-P.1
Garzon-Rodriguez, W.2
Glabe, C.G.3
Surewicz, W.K.4
-
122
-
-
0141891097
-
The association of a-synuclein with membranes affects bilayer structure, stability, and fibril formation
-
Zhu M, Li J, Fink AL (2003) The association of a-synuclein with membranes affects bilayer structure, stability, and fibril formation. J Biol Chem 278: 40186-40197.
-
(2003)
J Biol Chem
, vol.278
, pp. 40186-40197
-
-
Zhu, M.1
Li, J.2
Fink, A.L.3
-
123
-
-
44049099669
-
Mitochondrial import and accumulation of alpha-synuclein impair complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi L, Raghavendran V, Prabhu BM, Avadhani NG, Anandatheerthavarada HK (2008) Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J Biol Chem 283: 9089-9100.
-
(2008)
J Biol Chem
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
124
-
-
0037437192
-
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
-
Anandatheerthavarada HK, Biswas G, Robin M-A, Avadhani NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J Cell Biol 161:41-54.
-
(2003)
J Cell Biol
, vol.161
, pp. 41-54
-
-
Anandatheerthavarada, H.K.1
Biswas, G.2
Robin, M.-A.3
Avadhani, N.G.4
-
125
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
-
Du H, Guo L, Yan S, Sosunov AA, McKhann GM, Yan SS (2010) Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model. Proc Natl Acad Sci USA 107:18670-18675.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18670-18675
-
-
Du, H.1
Guo, L.2
Yan, S.3
Sosunov, A.A.4
McKhann, G.M.5
Yan, S.S.6
-
126
-
-
76149102617
-
Evidence for proteotoxicity in b cells in type 2 diabetes
-
Gurlo T, Ryazantsev S, Huang C-J, Yeh MW, Reber HA, Hines OJ, O'Brien TD, Glabe CG, Butler PC (2010) Evidence for proteotoxicity in b cells in type 2 diabetes. Am J Pathol 176:861-869.
-
(2010)
Am J Pathol
, vol.176
, pp. 861-869
-
-
Gurlo, T.1
Ryazantsev, S.2
Huang, C.-J.3
Yeh, M.W.4
Reber, H.A.5
Hines, O.J.6
O'brien, T.D.7
Glabe, C.G.8
Butler, P.C.9
-
127
-
-
77958124580
-
Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery
-
Zhang X, OgleRcka K, Sandgren S, Belting M, Esbjorner EK, Norden B, Graslund A (2010) Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery. Biochim Biophys Acta 1798:2201-2208.
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 2201-2208
-
-
Zhang, X.1
Oglercka, K.2
Sandgren, S.3
Belting, M.4
Esbjorner, E.K.5
Norden, B.6
Graslund, A.7
-
128
-
-
10644260444
-
Membrane translocation mechanism of the antimicrobial peptide buforin 2
-
Kobayashi S, Chikushi A, Tougu S, Imura Y, Nishida M, Yano Y, Matsuzaki K (2004) Membrane translocation mechanism of the antimicrobial peptide buforin 2. Biochemistry 43:15610-15616.
-
(2004)
Biochemistry
, vol.43
, pp. 15610-15616
-
-
Kobayashi, S.1
Chikushi, A.2
Tougu, S.3
Imura, Y.4
Nishida, M.5
Yano, Y.6
Matsuzaki, K.7
-
129
-
-
0037428394
-
Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes
-
Takeshima K, Chikushi A, Lee K-K, Yonehara S, Matsuzaki K (2003) Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes. J Biol Chem 278:1310-1315.
-
(2003)
J Biol Chem
, vol.278
, pp. 1310-1315
-
-
Takeshima, K.1
Chikushi, A.2
Lee, K.-K.3
Yonehara, S.4
Matsuzaki, K.5
-
130
-
-
0001439249
-
Structure-activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: The proline hinge is responsible for the cell-penetrating ability of buforin II
-
Park CB, Yi K-S, Matsuzaki K, Kim MS, Kim SC (2000) Structure-activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: the proline hinge is responsible for the cell-penetrating ability of buforin II. Proc Natl Acad Sci USA 97:8245-8250.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8245-8250
-
-
Park, C.B.1
Yi, K.-S.2
Matsuzaki, K.3
Kim, M.S.4
Kim, S.C.5
-
131
-
-
1442314720
-
Cell entry and antimicrobial properties of eukaryotic cell-penetrating peptides
-
Nekhotiaeva N, Elmquist A, Rajarao GK, Hallbrink M, Langel U, Good L (2004) Cell entry and antimicrobial properties of eukaryotic cell-penetrating peptides. FASEB J 18:394-396.
-
(2004)
FASEB J
, vol.18
, pp. 394-396
-
-
Nekhotiaeva, N.1
Elmquist, A.2
Rajarao, G.K.3
Hallbrink, M.4
Langel, U.5
Good, L.6
-
132
-
-
33744999374
-
Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects
-
Palm C, Netzereab S, Hallbrink M (2006) Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects. Peptides 27: 1710-1716.
-
(2006)
Peptides
, vol.27
, pp. 1710-1716
-
-
Palm, C.1
Netzereab, S.2
Hallbrink, M.3
-
133
-
-
71749110589
-
Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling
-
Kilk K, Mahlapuu R, Soomets U, Langel U (2009) Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology 265:87-95.
-
(2009)
Toxicology
, vol.265
, pp. 87-95
-
-
Kilk, K.1
Mahlapuu, R.2
Soomets, U.3
Langel, U.4
-
134
-
-
27644509147
-
Cell-penetrating peptides: A comparative membrane toxicity study
-
Saar K, Lindgren M, Hansen M, Eirksdottir E, Jiang Y, Rosenthal-Aizman K, Sassian M, Langel U (2005) Cell-penetrating peptides: a comparative membrane toxicity study. Anal Biochem 345:55-65.
-
(2005)
Anal Biochem
, vol.345
, pp. 55-65
-
-
Saar, K.1
Lindgren, M.2
Hansen, M.3
Eirksdottir, E.4
Jiang, Y.5
Rosenthal-Aizman, K.6
Sassian, M.7
Langel, U.8
-
135
-
-
27644561216
-
Characterisation of cell-penetrating peptide-mediated peptide delivery
-
Jones SW, Christison R, Bundell K, Voyce CJ, Brockbank SMV, Newham P, Lindsay MA (2005) Characterisation of cell-penetrating peptide-mediated peptide delivery. Br J Pharmacol 145:1093-1102.
-
(2005)
Br J Pharmacol
, vol.145
, pp. 1093-1102
-
-
Jones, S.W.1
Christison, R.2
Bundell, K.3
Voyce, C.J.4
Brockbank, S.M.V.5
Newham, P.6
Lindsay, M.A.7
-
136
-
-
70350023192
-
Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell-penetrating peptides
-
Herce HD, Garcia AE, Litt J, Kane RS, Martin P, Enrique N, Rebolledo A, Milesi V (2009) Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell-penetrating peptides. Biophys J 97:1917-1925.
-
(2009)
Biophys J
, vol.97
, pp. 1917-1925
-
-
Herce, H.D.1
Garcia, A.E.2
Litt, J.3
Kane, R.S.4
Martin, P.5
Enrique, N.6
Rebolledo, A.7
Milesi, V.8
|