Structure of α-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding

Journal of Biological Chemistry

Volumn 283, Issue 25, 2008, Pages 17205-17210

  Apostolidou, Melania ^a   Jayasinghe, Sajith A ^b   Langen, Ralf ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; ELECTRON SPIN RESONANCE SPECTROSCOPY; GLYCOPROTEINS; MODEL STRUCTURES; PARAMAGNETIC RESONANCE; THREE DIMENSIONAL;

C TERMINUSES; DIABETES MELLITUS; EPR SPECTROSCOPIES; HELICAL MEMBRANES; HELICAL STRUCTURES; HUMAN ISLETS; LOW DIELECTRICS; MISFOLDING; SECONDARY STRUCTURE FORMATIONS; SECONDARY STRUCTURES; STRUCTURAL MODELS; TERMINAL REGIONS;

MEMBRANES;

AMINO ACID; AMYLIN; AMYLOID; PEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DIELECTRIC CONSTANT; ELECTRON SPIN RESONANCE; HUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN MISFOLDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; SPIN LABELING; STRUCTURE ANALYSIS; ANIMAL; CELL MEMBRANE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PANCREAS ISLET; PROTEIN DENATURATION; RAT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMYLOID; ANIMALS; CELL MEMBRANE; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; ISLETS OF LANGERHANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SPIN LABELS;

EID: 47749117154     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801383200     Document Type: Article

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