Specificity and kinetics of α-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe

Journal of Biological Chemistry

Volumn 286, Issue 15, 2011, Pages 13023-13032

  Shvadchak, Volodymyr V ^a   Falomir Lockhart, Lisandro J ^a   Yushchenko, Dmytro A ^a   Jovin, Thomas M ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BI-LAYER; BINDING AFFINITIES; CHOLESTEROL CONTENT; DIFFERENT MECHANISMS; DISORDERED PHASE; EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER; FLUORESCENT PROBES; IN-VIVO; MEMBRANE CURVATURE; MEMBRANE PHYSICAL PROPERTIES; MICROAGGREGATES; MIDBRAIN; MODEL MEMBRANES; NEGATIVELY CHARGED MEMBRANES; NEURONAL PROTEINS; NEUROTOXICITY; OXIDATIVE MODIFICATION; PARKINSON DISEASE; PHYSIOPATHOLOGY; PRESYNAPTIC; PROTEIN LOCALIZATION; SYNUCLEIN; THERMAL TRANSITIONS;

BINDING ENERGY; CHOLESTEROL; DEFECTS; DISEASES; EXCITED STATES; FLUORESCENCE; OLIGOMERS; PARKS; PROBES; PROTEINS;

MEMBRANES;

ALPHA SYNUCLEIN;

AFFINITY LABELING; ARTICLE; ARTIFICIAL MEMBRANE; BINDING AFFINITY; CONTROLLED STUDY; MEMBRANE BINDING; MOLECULAR PROBE; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTON TRANSPORT; STOICHIOMETRY;

ALPHA-SYNUCLEIN; AMINO ACID SUBSTITUTION; CHOLESTEROL; FLUORESCENT DYES; HUMANS; KINETICS; MEMBRANES, ARTIFICIAL; MOLECULAR PROBES; MUTATION, MISSENSE; NEURONS; PARKINSON DISEASE; PROTONS; STATIC ELECTRICITY;

EID: 79953850289     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.204776     Document Type: Article

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