Mechanism and kinetics of δ-lysin interaction with phospholipid vesicles

Biochemistry

Volumn 41, Issue 36, 2002, Pages 11044-11056

  Pokorny, Antje ^a   Birkbeck, T Harry ^b   Almeida, Paulo F F ^a  

^a UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PORE FORMATIONS;

CELLS; ENERGY TRANSFER; FLUORESCENCE; MONOMERS; POLYMERIC MEMBRANES; RATE CONSTANTS; REACTION KINETICS;

LIPIDS;

AMINO ACID; CARBOXYFLUORESCEIN; DELTA LYSIN; LIPID; LYSINE; MONOMER; PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL INTERACTION; CELL VACUOLE; CYTOLYSIS; ENERGY TRANSFER; FLOW RATE; FLUORESCENCE; GENE INSERTION; KINETICS; LIPID VESICLE; MEMBRANE BINDING; MEMBRANE TRANSPORT; POROSITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN SECRETION; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; COUMARINS; ENERGY TRANSFER; FLUORESCEINS; HEMOLYSIN PROTEINS; KINETICS; LIPID BILAYERS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLCHOLINES; PHOSPHOLIPIDS; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; STAPHYLOCOCCUS AUREUS; TRYPTOPHAN; WATER;

BACTERIA (MICROORGANISMS); INSERTION SEQUENCES; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0036712127     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020244r     Document Type: Article

References (70)

1. Cell-lytic antibacterial peptides that act by perturbing the barrier function of membranes: Facets of their conformational features, structure - Function correlations and membrane-perturbing abilities
2. Animal antimicrobial peptides: An overview
3. Mode of action of linear amphipathic α-helical antimicrobial peptides
4. The role of cationic antimicrobial peptides in innate host defenses
5. Antimicrobial peptides of multicellular organisms
6. All-D amino acid-containing channel-forming antibiotic peptides
7. Innate antimicrobial peptide protects the skin from invasive bacterial infection
8. Hemolytic and antimicrobial activities of the twenty-four individual omission analogues of melittin
9. Interaction of wasp venom mastoparan with biomembranes
10. Purification and properties of staphylococcal delta hemolysin
11. δ-toxin, unlike melittin, has only hemolytic activity and no antimicrobial activity: Rationalization of this specific biological activity
12. The amino acid sequence of the delta haemolysin of Staphylococcus aureus
13. Physicochemical studies on delta haemolysin, a staphylococcal cytolytic polypeptide
14. The amphiphilic alpha-helix concept. Consequences on the structure of staphylococcal δ-toxin in solution and bound to lipids
15. Dynamics and orientation of amphipathic peptides in solution and bound to membranes: A steady-state and time-resolved fluorescence study of staphylococcal δ-toxin and its synthetic analogues
16. Modulation of magainin 2-lipid bilayer interactions by peptide charge
17. Diversity of antimicrobial peptides and their mechanisms of action
18. Binding of antibacterial magainin peptides to electrically neutral membranes: Thermodynamics and structure
19. Magainin 2 amide interaction with lipid membranes: Calorimetric detection of peptide binding and pore formation
20. Interaction of Staphylococcus aureus δ-lysin with phospholipid monolayers
21. Structural features of helical antimicrobial peptides: Their potential to modulate activity on model membranes and biological cells
22. Possible conformation of δ-lysin, a membrane-damaging peptide of Staphylococcus aureus
23. Properties of ion channels formed by Staphylococcus aureus δ-toxin
24. Models of δ-hemolysin membrane channels and crystal structures
25. Ion channel formation by synthetic analogues of Staphylococcal δ-toxin
26. Molecular modelling of staphylococcal δ-toxin ion channels by restrained molecular dynamics
27. Phosphorous assay in column chromatography
28. Purification and assay of staphylococcal δ-lysin
29. Isolation and composition of staphyococcal alpha-toxin
30. Kinetics of amphiphile association with two-phase lipid bilayer vesicles
31. Association of a fluorescent amphiphile with lipid bilayer vesicles in regions of solid-liquid-disordered phase coexistence
32. Physics of chemoreception
33. The use of singlet-singlet energy transfer to study macromolecular assemblies
34. Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore
35. Mechanism of synergism etween antimicrobial peptides magainin 2 and PGLa
36. Determining the membrane topology of peptides by fluorescence quenching
37. Studies of kinetics and equilibrium membrane binding of class A and class L model amphipathic peptides
38. Kinetics and mechanism of the recognition of endotoxin by polymyxin B
39. An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation
40. Transbilayer transport of ions and lipids coupled with mastoparan X translocation
41. Models of δ-hemolysin membrane channels and crystal structures
42. Kinetics of pore formation by an antimicrobial peptide, magainin 2, in phospholipid bilayers
43. Membrane protein folding and stability: Physical principles
44. General aspects of peptide selectivity towards lipid bilayers and cell membranes studied by variation of the structural parameters of amphipathic helical model peptides
45. Influence of the angle subtended by the positively charged helix face on the membrane activity of amphipathic, antibacterial peptides
46. Polar angle as a determinant of amphipathic α-helix-lipid interactions: A model peptide study
47. The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solidstate NMR spectroscopy
48. Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy
49. The solution conformation of the antibacterial peptide cecropin A: A nuclear magnetic resonance and dynamical simulated annealing study
50. Interactions of the novel antimicrobial peptide buforin 2 with lipid bilayers: Proline as a translocation promoting factor
51. Effect of phospholipid composition on an amphipathic peptide-mediated pore formation in bilayer vesicles
52. Relationship of membrane curvature to the formation of pores by magainin 2
53. Mode of action of the antibacterial cecropin B2: A spectrofluorometric study
54. Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles
55. Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes
56. Spectrum of antimicrobial activity and assembly of dermaseptin-b and its precursor form in phospholipid membranes
57. Raman spectroscopy of synthetic antimicrobial frog peptides magainin 2a and PGLa
58. Electric potentiation, cooperativity, and synergism of magainin peptides in protein-free liposomes
59. Functional synergism of the magainins PGLa and magainin-2 in Escherichia coli, tumor cells and liposomes
60. Interaction between staphylococcal δ-lysin with phospholipid monolayers and bilayers - A short review
61. 31P nuclear magnetic resonance, Fourier transform infrared spectroscopy, and X-ray diffraction studies
62. Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli
63. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures