메뉴 건너뛰기




Volumn 132, Issue 3 PART 2, 2012, Pages 887-895

Antimicrobial peptides: Old molecules with new ideas

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; BAC5 PEPTIDE; BETA DEFENSIN; CALGRANULIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CECROPIN; CECROPIN A; CECROPIN B; CECROPIN P1; DEFENSIN; DERMCIDIN; GAMMA PUROTHIONIN DERIVATIVE; GRAMICIDIN; PENICILLIN G; POLYPEPTIDE ANTIBIOTIC AGENT; THETA DEFENSIN; UNCLASSIFIED DRUG;

EID: 84856864352     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.387     Document Type: Review
Times cited : (321)

References (144)
  • 1
    • 77956881915 scopus 로고    scopus 로고
    • The antimicrobial heterodimer S100A8/S100A9 (calprotectin) is upregulated by bacterial flagellin in human epidermal keratinocytes
    • Abtin A, Eckhart L, Glaser R et al. (2010) The antimicrobial heterodimer S100A8/S100A9 (calprotectin) is upregulated by bacterial flagellin in human epidermal keratinocytes. J Invest Dermatol 130:2423-30
    • (2010) J Invest Dermatol , vol.130 , pp. 2423-2430
    • Abtin, A.1    Eckhart, L.2    Glaser, R.3
  • 2
    • 70349745535 scopus 로고    scopus 로고
    • Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7
    • Abtin A, Eckhart L, Mildner M et al. (2009) Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7. J Invest Dermatol 129:2193-201
    • (2009) J Invest Dermatol , vol.129 , pp. 2193-2201
    • Abtin, A.1    Eckhart, L.2    Mildner, M.3
  • 3
    • 0028942078 scopus 로고
    • FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
    • Agerberth B, Gunne H, Odeberg J et al. (1995) FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci USA 92:195-9
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 195-199
    • Agerberth, B.1    Gunne, H.2    Odeberg, J.3
  • 4
    • 0034946112 scopus 로고    scopus 로고
    • Expression of the peptide antibiotics human β defensin-1 and human β defensin-2 in normal human skin
    • DOI 10.1046/j.0022-202X.2001.01401.x
    • Ali RS, Falconer A, Ikram M et al. (2001) Expression of the peptide antibiotics human beta defensin-1 and human beta defensin-2 in normal human skin. J Invest Dermatol 117:106-11 (Pubitemid 32652446)
    • (2001) Journal of Investigative Dermatology , vol.117 , Issue.1 , pp. 106-111
    • Ali, R.S.1    Falconer, A.2    Ikram, M.3    Bissett, C.E.4    Cerio, R.5    Quinn, A.G.6
  • 5
    • 0037362455 scopus 로고    scopus 로고
    • Ascaris nematodes from pig and human make three antibacterial peptides: Isolation of cecropin P1 and two ASABF peptides
    • DOI 10.1007/s000180300051
    • Andersson M, Boman A, Boman HG (2003) Ascaris nematodes from pig and human make three antibacterial peptides: Isolation of cecropin P1 and two ASABF peptides. Cell Mol Life Sci 60:599-606 (Pubitemid 36459538)
    • (2003) Cellular and Molecular Life Sciences , vol.60 , Issue.3 , pp. 599-606
    • Andersson, M.1    Boman, A.2    Boman, H.G.3
  • 6
    • 0001131393 scopus 로고
    • A crystalline protein obtained from a lipoprotein of wheat flour
    • Balls AK, Hale WS, Harris TH (1942) A crystalline protein obtained from a lipoprotein of wheat flour. Cereal Chem 19:279-88
    • (1942) Cereal Chem , vol.19 , pp. 279-288
    • Balls, A.K.1    Hale, W.S.2    Harris, T.H.3
  • 8
    • 0034682860 scopus 로고    scopus 로고
    • Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase
    • Belaaouaj A, Kim KS, Shapiro SD (2000) Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science 289:1185-8
    • (2000) Science , vol.289 , pp. 1185-1188
    • Belaaouaj, A.1    Kim, K.S.2    Shapiro, S.D.3
  • 9
    • 0028981702 scopus 로고
    • HBD-1: A novel beta-defensin from human plasma
    • Bensch KW, Raida M, Magert HJ et al. (1995) hBD-1: A novel beta-defensin from human plasma. FEBS Lett 368:331-5
    • (1995) FEBS Lett , vol.368 , pp. 331-335
    • Bensch, K.W.1    Raida, M.2    Magert, H.J.3
  • 11
    • 0029347190 scopus 로고
    • Plant defensins: Novel antimicrobial peptides as components of the host defense system
    • Broekaert WF, Terras FR, Cammue BP et al. (1995) Plant defensins: Novel antimicrobial peptides as components of the host defense system. Plant Physiol 108:1353-8
    • (1995) Plant Physiol , vol.108 , pp. 1353-1358
    • Broekaert, W.F.1    Terras, F.R.2    Cammue, B.P.3
  • 12
    • 0027395308 scopus 로고
    • 1H-NMR: A structural motif common to toxic arthropod proteins
    • DOI 10.1021/bi00053a041
    • Bruix M, Jimenez MA, Santoro J et al. (1993) Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: A structural motif common to toxic arthropod proteins. Biochemistry 32:715-24 (Pubitemid 23034913)
    • (1993) Biochemistry , vol.32 , Issue.2 , pp. 715-724
    • Bruix, M.1    Jimenez, M.A.2    Santoro, J.3    Gonzalez, C.4    Colilla, F.J.5    Mendez, E.6    Rico, M.7
  • 13
    • 1642545489 scopus 로고    scopus 로고
    • Anti-microbial peptides: From invertebrates to vertebrates
    • DOI 10.1111/j.0105-2896.2004.0124.x
    • Bulet P, Stocklin R, Menin L (2004) Anti-microbial peptides: From invertebrates to vertebrates. Immunol Rev 198:169-84 (Pubitemid 38406943)
    • (2004) Immunological Reviews , vol.198 , pp. 169-184
    • Bulet, P.1    Stocklin, R.2    Menin, L.3
  • 15
    • 0000385093 scopus 로고
    • The amino acid sequence of egg white lysozyme
    • Canfield RE (1963) The amino acid sequence of egg white lysozyme. J Biol Chem 238:2698-707
    • (1963) J Biol Chem , vol.238 , pp. 2698-2707
    • Canfield, R.E.1
  • 16
    • 23344438908 scopus 로고    scopus 로고
    • Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss
    • DOI 10.1128/IAI.73.8.5053-5064.2005
    • Chang CI, Pleguezuelos O, Zhang YA et al. (2005) Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss. Infect Immun 73:5053-64 (Pubitemid 41105664)
    • (2005) Infection and Immunity , vol.73 , Issue.8 , pp. 5053-5064
    • Chang, C.-I.1    Pleguezuelos, O.2    Zhang, Y.-A.3    Zou, J.4    Secombes, C.J.5
  • 18
    • 77649121135 scopus 로고    scopus 로고
    • Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus
    • Cogen AL, Yamasaki K, Muto J et al. (2010a) Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One 5:e8557
    • (2010) PLoS One , vol.5
    • Cogen, A.L.1    Yamasaki, K.2    Muto, J.3
  • 19
    • 72049093749 scopus 로고    scopus 로고
    • Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin
    • Cogen AL, Yamasaki K, Sanchez KM et al. (2010b) Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol 130:192-200
    • (2010) J Invest Dermatol , vol.130 , pp. 192-200
    • Cogen, A.L.1    Yamasaki, K.2    Sanchez, K.M.3
  • 21
    • 0025080513 scopus 로고
    • γ-Purothionins: Amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm
    • DOI 10.1016/0014-5793(90)81265-P
    • Colilla FJ, Rocher A, Mendez E (1990) gamma-Purothionins: Amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. FEBS Lett 270:191-4 (Pubitemid 20288599)
    • (1990) FEBS Letters , vol.270 , Issue.1-2 , pp. 191-194
    • Colilla, F.J.1    Rocher, A.2    Mendez, E.3
  • 22
    • 0036740432 scopus 로고    scopus 로고
    • The antimicrobial peptide LL-37 is expressed by keratinocytes in condyloma acuminatum and verruca vulgaris
    • Conner K, Nern K, Rudisill J et al. (2002) The antimicrobial peptide LL-37 is expressed by keratinocytes in condyloma acuminatum and verruca vulgaris. J Am Acad Dermatol 47:347-50
    • (2002) J Am Acad Dermatol , vol.47 , pp. 347-350
    • Conner, K.1    Nern, K.2    Rudisill, J.3
  • 23
    • 0029007198 scopus 로고
    • HCAP-18, a cathelin/probactenecin-like protein of human neutrophil specific granules
    • Cowland JB, Johnsen AH, Borregaard N (1995) hCAP-18, a cathelin/probactenecin-like protein of human neutrophil specific granules. FEBS Lett 368:173-6
    • (1995) FEBS Lett , vol.368 , pp. 173-176
    • Cowland, J.B.1    Johnsen, A.H.2    Borregaard, N.3
  • 25
    • 0033805035 scopus 로고    scopus 로고
    • Antimicrobial effects of alpha-MSH peptides
    • Cutuli M, Cristiani S, Lipton JM et al. (2000) Antimicrobial effects of alpha-MSH peptides. J Leukoc Biol 67:233-9
    • (2000) J Leukoc Biol , vol.67 , pp. 233-239
    • Cutuli, M.1    Cristiani, S.2    Lipton, J.M.3
  • 26
    • 0034596945 scopus 로고    scopus 로고
    • LL-37, the neutrophil granule-and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells
    • De Y, Chen Q, Schmidt AP et al. (2000) LL-37, the neutrophil granule-and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192: 1069-74
    • (2000) J Exp Med , vol.192 , pp. 1069-1074
    • De Y Chen, Q.1    Schmidt, A.P.2
  • 27
    • 77955745045 scopus 로고    scopus 로고
    • Arabidopsis thaliana plant defensin AtPDF1.1 is involved in the plant response to biotic stress
    • De Coninck BM, Sels J, Venmans E et al. (2010) Arabidopsis thaliana plant defensin AtPDF1.1 is involved in the plant response to biotic stress. New Phytol 187:1075-88
    • (2010) New Phytol , vol.187 , pp. 1075-1088
    • De Coninck, B.M.1    Sels, J.2    Venmans, E.3
  • 28
    • 0345074069 scopus 로고    scopus 로고
    • Cutting edge: Mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide
    • Di Nardo A, Vitiello A, Gallo RL (2003) Cutting edge: Mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol 170:2274-8 (Pubitemid 36245611)
    • (2003) Journal of Immunology , vol.170 , Issue.5 , pp. 2274-2278
    • Di Nardo, A.1    Vitiello, A.2    Gallo, R.L.3
  • 30
    • 67649160595 scopus 로고    scopus 로고
    • Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D
    • Doss M, White MR, Tecle T et al. (2009) Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D. J Immunol 182:7878-87
    • (2009) J Immunol , vol.182 , pp. 7878-7887
    • Doss, M.1    White, M.R.2    Tecle, T.3
  • 31
    • 74949124734 scopus 로고    scopus 로고
    • Human defensins and LL-37 in mucosal immunity
    • Doss M, White MR, Tecle T et al. (2010) Human defensins and LL-37 in mucosal immunity. J Leukoc Biol 87:79-92
    • (2010) J Leukoc Biol , vol.87 , pp. 79-92
    • Doss, M.1    White, M.R.2    Tecle, T.3
  • 32
    • 85024321592 scopus 로고
    • Studies on a bactericidal agent extracted from a soil bacillus: I. Preparation of the agent. Its activity in vitro
    • Dubos RJ (1939a) Studies on a bactericidal agent extracted from a soil bacillus: I. Preparation of the agent. Its activity in vitro. J Exp Med 70:1-10
    • (1939) J Exp Med , vol.70 , pp. 1-10
    • Dubos, R.J.1
  • 33
    • 85025377717 scopus 로고
    • Studies on a bactericidal agent extracted from a soil bacillus: II. Protective effect of the bactericidal agent against experimental pneumococcus infection in mice
    • Dubos RJ (1939b) Studies on a bactericidal agent extracted from a soil bacillus: II. Protective effect of the bactericidal agent against experimental pneumococcus infection in mice. J Exp Med 70:11-7
    • (1939) J Exp Med , vol.70 , pp. 11-17
    • Dubos, R.J.1
  • 34
    • 0000646464 scopus 로고
    • On a remarkable bacteriolytic element found in tissues and secretions
    • Fleming A (1922) On a remarkable bacteriolytic element found in tissues and secretions. Proc R Soc London B 93:306-17
    • (1922) Proc R Soc London B , vol.93 , pp. 306-317
    • Fleming, A.1
  • 35
    • 0000378637 scopus 로고
    • On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. influenzae
    • Fleming A (1929) On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. influenzae. Br J Exp Pathol 10:226-36
    • (1929) Br J Exp Pathol , vol.10 , pp. 226-236
    • Fleming, A.1
  • 36
    • 0025065276 scopus 로고
    • Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils
    • Frank RW, Gennaro R, Schneider K et al. (1990) Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils. J Biol Chem 265:18871-4
    • (1990) J Biol Chem , vol.265 , pp. 18871-18874
    • Frank, R.W.1    Gennaro, R.2    Schneider, K.3
  • 39
    • 25144453335 scopus 로고    scopus 로고
    • Regulation of mammalian defensin expression by Toll-like receptor-dependent and independent signalling pathways
    • DOI 10.1111/j.1462-5822.2005.00590.x
    • Froy O (2005) Regulation of mammalian defensin expression by Toll-like receptor-dependent and independent signalling pathways. Cell Microbiol 7:1387-97 (Pubitemid 41335243)
    • (2005) Cellular Microbiology , vol.7 , Issue.10 , pp. 1387-1397
    • Froy, O.1
  • 40
    • 33947579340 scopus 로고    scopus 로고
    • α-defensins block the early steps of HIV-1 infection: Interference with the binding of gp120 to CD4
    • DOI 10.1182/blood-2006-05-024489
    • Furci L, Sironi F, Tolazzi M et al. (2007) Alpha-defensins block the early steps of HIV-1 infection: Interference with the binding of gp120 to CD4. Blood 109:2928-35 (Pubitemid 46482090)
    • (2007) Blood , vol.109 , Issue.7 , pp. 2928-2935
    • Furci, L.1    Sironi, F.2    Tolazzi, M.3    Vassena, L.4    Lusso, P.5
  • 42
    • 0036884492 scopus 로고    scopus 로고
    • Biology and clinical relevance of naturally occurring antimicrobial peptides
    • Gallo RL, Murakami M, Ohtake T et al. (2002) Biology and clinical relevance of naturally occurring antimicrobial peptides. J Allergy Clin Immunol 110:823-31
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 823-831
    • Gallo, R.L.1    Murakami, M.2    Ohtake, T.3
  • 43
    • 80052825794 scopus 로고    scopus 로고
    • Microbial symbiosis with the innate immune defense system of the skin
    • Gallo RL, Nakatsuji T (2011) Microbial symbiosis with the innate immune defense system of the skin. J Invest Dermatol 131:1974-80
    • (2011) J Invest Dermatol , vol.131 , pp. 1974-1980
    • Gallo, R.L.1    Nakatsuji, T.2
  • 45
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • Ganguly D, Chamilos G, Lande R et al. (2009) Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med 206:1983-94
    • (2009) J Exp Med , vol.206 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3
  • 46
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • DOI 10.1038/nri1180
    • Ganz T (2003) Defensins: Antimicrobial peptides of innate immunity. Nat Rev Immunol 3:710-20 (Pubitemid 41070812)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.9 , pp. 710-720
    • Ganz, T.1
  • 47
  • 48
    • 0001131165 scopus 로고
    • Gramicidin S and its use in the treatment of infected wounds
    • Gause GF, Brazhnicova MG (1944) Gramicidin S and its use in the treatment of infected wounds. Nature 3918:703
    • (1944) Nature , vol.3918 , pp. 703
    • Gause, G.F.1    Brazhnicova, M.G.2
  • 50
    • 21344435975 scopus 로고    scopus 로고
    • Human cathelicidin (LL-37), a multifunctional peptide, is expressed by ocular surface epithelia and has potent antibacterial and antiviral activity
    • DOI 10.1080/02713680590934111
    • Gordon YJ, Huang LC, Romanowski EG et al. (2005) Human cathelicidin (LL-37), a multifunctional peptide, is expressed by ocular surface epithelia and has potent antibacterial and antiviral activity. Curr Eye Res 30:385-94 (Pubitemid 40910819)
    • (2005) Current Eye Research , vol.30 , Issue.5 , pp. 385-394
    • Gordon, Y.J.1    Huang, L.C.2    Romanowski, E.G.3    Yates, K.A.4    Proske, R.J.5    McDermott, A.M.6
  • 51
    • 66349083859 scopus 로고    scopus 로고
    • Topographical and temporal diversity of the human skin microbiome
    • Grice EA, Kong HH, Conlan S et al. (2009) Topographical and temporal diversity of the human skin microbiome. Science 324:1190-2
    • (2009) Science , vol.324 , pp. 1190-1192
    • Grice, E.A.1    Kong, H.H.2    Conlan, S.3
  • 52
    • 72449155528 scopus 로고    scopus 로고
    • Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis
    • Gutner M, Chaushu S, Balter D et al. (2009) Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis. Infect Immun 77:5558-63
    • (2009) Infect Immun , vol.77 , pp. 5558-5563
    • Gutner, M.1    Chaushu, S.2    Balter, D.3
  • 53
    • 0030820726 scopus 로고    scopus 로고
    • A peptide antibiotic from human skin
    • Harder J, Bartels J, Christophers E et al. (1997) A peptide antibiotic from human skin. Nature 387:861
    • (1997) Nature , vol.387 , pp. 861
    • Harder, J.1    Bartels, J.2    Christophers, E.3
  • 54
    • 0035937107 scopus 로고    scopus 로고
    • Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic
    • Harder J, Bartels J, Christophers E et al. (2001) Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 276:5707-13
    • (2001) J Biol Chem , vol.276 , pp. 5707-5713
    • Harder, J.1    Bartels, J.2    Christophers, E.3
  • 55
    • 77951090253 scopus 로고    scopus 로고
    • Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury
    • Harder J, Dressel S, Wittersheim M et al. (2010) Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury. J Invest Dermatol 130:1355-64
    • (2010) J Invest Dermatol , vol.130 , pp. 1355-1364
    • Harder, J.1    Dressel, S.2    Wittersheim, M.3
  • 56
    • 0037195896 scopus 로고    scopus 로고
    • RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
    • DOI 10.1074/jbc.M207587200
    • Harder J, Schroder JM (2002) RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J Biol Chem 277:46779-84 (Pubitemid 35417681)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.48 , pp. 46779-46784
    • Harder, J.1    Schroder, J.-M.2
  • 57
    • 16844370194 scopus 로고    scopus 로고
    • Psoriatic scales: A promising source for the isolation of human skin-derived antimicrobial proteins
    • DOI 10.1189/jlb.0704409
    • Harder J, Schroder JM (2005) Psoriatic scales: A promising source for the isolation of human skin-derived antimicrobial proteins. J Leukoc Biol 77:476-86 (Pubitemid 40489523)
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.4 , pp. 476-486
    • Harder, J.1    Schroder, J.-M.2
  • 58
    • 77955894822 scopus 로고    scopus 로고
    • History of eczema herpeticum is associated with the inability to induce human beta-defensin (HBD)-2, HBD-3 and cathelicidin in the skin of patients with atopic dermatitis
    • Hata TR, Kotol P, Boguniewicz M et al. (2010) History of eczema herpeticum is associated with the inability to induce human beta-defensin (HBD)-2, HBD-3 and cathelicidin in the skin of patients with atopic dermatitis. Br J Dermatol 163:659-61
    • (2010) Br J Dermatol , vol.163 , pp. 659-661
    • Hata, T.R.1    Kotol, P.2    Boguniewicz, M.3
  • 59
    • 53049094390 scopus 로고    scopus 로고
    • Administration of oral vitamin D induces cathelicidin production in atopic individuals
    • Hata TR, Kotol P, Jackson M et al. (2008) Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol 122:829-31
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 829-831
    • Hata, T.R.1    Kotol, P.2    Jackson, M.3
  • 62
    • 33947513637 scopus 로고    scopus 로고
    • The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity
    • Huang YC, Lin YM, Chang TW et al. (2007) The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity. J Biol Chem 282:4626-33
    • (2007) J Biol Chem , vol.282 , pp. 4626-4633
    • Huang, Y.C.1    Lin, Y.M.2    Chang, T.W.3
  • 63
    • 58349114242 scopus 로고    scopus 로고
    • Expression of Dm-AMP1 in rice confers resistance to Magnaporthe oryzae and Rhizoctonia solani
    • Jha S, Tank HG, Prasad BD et al. (2009) Expression of Dm-AMP1 in rice confers resistance to Magnaporthe oryzae and Rhizoctonia solani. Transgenic Res 18:59-69
    • (2009) Transgenic Res , vol.18 , pp. 59-69
    • Jha, S.1    Tank, H.G.2    Prasad, B.D.3
  • 64
    • 78651394086 scopus 로고    scopus 로고
    • EGFR and IL-1 signaling synergistically promote keratinocyte antimicrobial defenses in a differentiation-dependent manner
    • Johnston A, Gudjonsson JE, Aphale A et al. (2011) EGFR and IL-1 signaling synergistically promote keratinocyte antimicrobial defenses in a differentiation-dependent manner. J Invest Dermatol 131:329-37
    • (2011) J Invest Dermatol , vol.131 , pp. 329-337
    • Johnston, A.1    Gudjonsson, J.E.2    Aphale, A.3
  • 66
    • 0016762430 scopus 로고
    • Distribution and persistence of Staphylococcus and Micrococcus species and other aerobic bacteria on human skin
    • Kloos WE, Musselwhite MS (1975) Distribution and persistence of Staphylococcus and Micrococcus species and other aerobic bacteria on human skin. Appl Microbiol 30:381-5
    • (1975) Appl Microbiol , vol.30 , pp. 381-385
    • Kloos, W.E.1    Musselwhite, M.S.2
  • 69
    • 79958849098 scopus 로고    scopus 로고
    • Expression of antimicrobial peptides in different subtypes of cutaneous lupus erythematosus
    • Kreuter A, Jaouhar M, Skrygan M et al. (2011) Expression of antimicrobial peptides in different subtypes of cutaneous lupus erythematosus. J Am Acad Dermatol 65:125-33
    • (2011) J Am Acad Dermatol , vol.65 , pp. 125-133
    • Kreuter, A.1    Jaouhar, M.2    Skrygan, M.3
  • 70
    • 79955971446 scopus 로고    scopus 로고
    • Mammalian antimicrobial peptide influences control of cutaneous Leishmania infection
    • Kulkarni MM, Barbi J, McMaster WR et al. (2011) Mammalian antimicrobial peptide influences control of cutaneous Leishmania infection. Cell Microbiol 13:913-23
    • (2011) Cell Microbiol , vol.13 , pp. 913-923
    • Kulkarni, M.M.1    Barbi, J.2    McMaster, W.R.3
  • 71
    • 77955708980 scopus 로고    scopus 로고
    • Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections
    • Lai Y, Cogen AL, Radek KA et al. (2010) Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol 130:2211-21
    • (2010) J Invest Dermatol , vol.130 , pp. 2211-2221
    • Lai, Y.1    Cogen, A.L.2    Radek, K.A.3
  • 72
    • 61349169039 scopus 로고    scopus 로고
    • AMPed up immunity: How antimicrobial peptides have multiple roles in immune defense
    • Lai Y, Gallo RL (2009) AMPed up immunity: How antimicrobial peptides have multiple roles in immune defense. Trends Immunol 30:131-41
    • (2009) Trends Immunol , vol.30 , pp. 131-141
    • Lai, Y.1    Gallo, R.L.2
  • 73
    • 79952468782 scopus 로고    scopus 로고
    • Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
    • Lande R, Ganguly D, Facchinetti V et al. (2011) Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med 3:73ra19
    • (2011) Sci Transl Med , vol.3
    • Lande, R.1    Ganguly, D.2    Facchinetti, V.3
  • 75
    • 70349158577 scopus 로고    scopus 로고
    • Histone H4 is a major component of the antimicrobial action of human sebocytes
    • Lee DY, Huang CM, Nakatsuji T et al. (2009a) Histone H4 is a major component of the antimicrobial action of human sebocytes. J Invest Dermatol 129:2489-96
    • (2009) J Invest Dermatol , vol.129 , pp. 2489-2496
    • Lee, D.Y.1    Huang, C.M.2    Nakatsuji, T.3
  • 76
    • 70349158577 scopus 로고    scopus 로고
    • Histone H4 is a major component of the antimicrobial action of human sebocytes
    • Lee DY, Huang CM, Nakatsuji T et al. (2009b) Histone H4 is a major component of the antimicrobial action of human sebocytes. J Invest Dermatol 129:2489-96
    • (2009) J Invest Dermatol , vol.129 , pp. 2489-2496
    • Lee, D.Y.1    Huang, C.M.2    Nakatsuji, T.3
  • 80
    • 0036135697 scopus 로고    scopus 로고
    • Cathelicidins: A family of endogenous antimicrobial peptides
    • DOI 10.1097/00062752-200201000-00004
    • Lehrer RI, Ganz T (2002) Cathelicidins: A family of endogenous antimicrobial peptides. Curr Opin Hematol 9:18-22 (Pubitemid 34025307)
    • (2002) Current Opinion in Hematology , vol.9 , Issue.1 , pp. 18-22
    • Lehrer, R.I.1    Ganz, T.2
  • 81
    • 0021847049 scopus 로고
    • Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity
    • Lehrer RI, Szklarek D, Ganz T et al. (1985) Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity. Infect Immun 49:207-11 (Pubitemid 15062890)
    • (1985) Infection and Immunity , vol.49 , Issue.1 , pp. 207-211
    • Lehrer, R.I.1    Szklarek, D.2    Ganz, T.3    Selsted, M.E.4
  • 82
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H et al. (2006) Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311:1770-3
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3
  • 83
    • 40149107558 scopus 로고    scopus 로고
    • Bacterial DNA indicated as an important inducer of fish cathelicidins
    • Maier VH, Schmitt CN, Gudmundsdottir S et al. (2008) Bacterial DNA indicated as an important inducer of fish cathelicidins. Mol Immunol 45:2352-8
    • (2008) Mol Immunol , vol.45 , pp. 2352-2358
    • Maier, V.H.1    Schmitt, C.N.2    Gudmundsdottir, S.3
  • 84
    • 77953148855 scopus 로고    scopus 로고
    • Injury downregulates the expression of the human cathelicidin protein hCAP18/LL-37 in atopic dermatitis
    • Mallbris L, Carlen L, Wei T et al. (2010) Injury downregulates the expression of the human cathelicidin protein hCAP18/LL-37 in atopic dermatitis. Exp Dermatol 19:442-9
    • (2010) Exp Dermatol , vol.19 , pp. 442-449
    • Mallbris, L.1    Carlen, L.2    Wei, T.3
  • 86
    • 75849145751 scopus 로고    scopus 로고
    • Increased expression of human beta-defensin 3 in mollusca contagiosum
    • Meyer-Hoffert U, Schwarz T, Schroder JM et al. (2010) Increased expression of human beta-defensin 3 in mollusca contagiosum. Clin Exp Dermatol 35:190-2
    • (2010) Clin Exp Dermatol , vol.35 , pp. 190-192
    • Meyer-Hoffert, U.1    Schwarz, T.2    Schroder, J.M.3
  • 87
    • 0043065436 scopus 로고    scopus 로고
    • Supernatants of Pseudomonas aeruginosa induce the Pseudomonas-specific antibiotic elafin in human keratinocytes
    • DOI 10.1034/j.1600-0625.2002.120409.x
    • Meyer-Hoffert U, Wichmann N, Schwichtenberg L et al. (2003) Supernatants of Pseudomonas aeruginosa induce the Pseudomonas-specific antibiotic elafin in human keratinocytes. Exp Dermatol 12:418-25 (Pubitemid 36992416)
    • (2003) Experimental Dermatology , vol.12 , Issue.4 , pp. 418-425
    • Meyer-Hoffert, U.1    Wichmann, N.2    Schwichtenberg, L.3    White, P.C.4    Wiedow, O.5
  • 89
    • 84856100861 scopus 로고    scopus 로고
    • Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands
    • e-pub ahead of print 18 August 2011
    • Morizane S, Yamasaki K, Mühleisen B et al. (2011) Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands. J Invest Dermatol; e-pub ahead of print 18 August 2011
    • (2011) J Invest Dermatol
    • Morizane, S.1    Yamasaki, K.2    Mühleisen, B.3
  • 90
    • 1342282224 scopus 로고    scopus 로고
    • Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense
    • Murakami M, Lopez-Garcia B, Braff M et al. (2004) Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense. J Immunol 172:3070-7 (Pubitemid 38263696)
    • (2004) Journal of Immunology , vol.172 , Issue.5 , pp. 3070-3077
    • Murakami, M.1    Lopez-Garcia, B.2    Braff, M.3    Dorschner, R.A.4    Gallo, R.L.5
  • 91
    • 33748366355 scopus 로고    scopus 로고
    • Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes
    • DOI 10.1016/j.micinf.2006.04.001, PII S1286457906001523
    • Nagy I, Pivarcsi A, Kis K et al. (2006) Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes. Microbes Infect 8:2195-205 (Pubitemid 44335873)
    • (2006) Microbes and Infection , vol.8 , Issue.8 , pp. 2195-2205
    • Nagy, I.1    Pivarcsi, A.2    Kis, K.3    Koreck, A.4    Bodai, L.5    McDowell, A.6    Seltmann, H.7    Patrick, S.8    Zouboulis, C.C.9    Kemeny, L.10
  • 92
    • 77949541112 scopus 로고    scopus 로고
    • Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating betadefensin-2 expression
    • Nakatsuji T, Kao MC, Zhang L et al. (2010) Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating betadefensin-2 expression. J Invest Dermatol 130:985-94
    • (2010) J Invest Dermatol , vol.130 , pp. 985-994
    • Nakatsuji, T.1    Kao, M.C.2    Zhang, L.3
  • 93
    • 1042302158 scopus 로고    scopus 로고
    • Evolution of primate θ-defensins: A serpentine path to a sweet tooth
    • DOI 10.1016/j.peptides.2003.07.023
    • Nguyen TX, Cole AM, Lehrer RI (2003) Evolution of primate theta-defensins: A serpentine path to a sweet tooth. Peptides 24:1647-54 (Pubitemid 38198072)
    • (2003) Peptides , vol.24 , Issue.11 , pp. 1647-1654
    • Nguyen, T.X.1    Cole, A.M.2    Lehrer, R.I.3
  • 94
    • 0036240209 scopus 로고    scopus 로고
    • A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis
    • DOI 10.1046/j.1365-2567.2002.01398.x
    • Niyonsaba F, Iwabuchi K, Someya A et al. (2002) A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis. Immunology 106:20-6 (Pubitemid 34437873)
    • (2002) Immunology , vol.106 , Issue.1 , pp. 20-26
    • Niyonsaba, F.1    Iwabuchi, K.2    Someya, A.3    Hirata, M.4    Matsuda, H.5    Ogawa, H.6    Nagaoka, I.7
  • 96
    • 0037057645 scopus 로고    scopus 로고
    • Endogenous antimicrobial peptides and skin infections in atopic dermatitis
    • Ong PY, Ohtake T, Brandt C et al. (2002) Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 347:1151-60
    • (2002) N Engl J Med , vol.347 , pp. 1151-1160
    • Ong, P.Y.1    Ohtake, T.2    Brandt, C.3
  • 98
    • 0018925929 scopus 로고
    • Microbicidal cationic proteins in rabbit alveolar macrophages: A potential host defense mechanism
    • Patterson-Delafield J, Martinez RJ, Lehrer RI (1980) Microbicidal cationic proteins in rabbit alveolar macrophages: A potential host defense mechanism. Infect Immun 30:180-92 (Pubitemid 10018871)
    • (1980) Infection and Immunity , vol.30 , Issue.1 , pp. 180-192
    • Patterson-Delafield, J.1    Martinez, R.J.2    Lehrer, R.I.3
  • 99
    • 67749111996 scopus 로고    scopus 로고
    • Vitamin D analogs differentially control antimicrobial peptide/''alarmin'' expression in psoriasis
    • Peric M, Koglin S, Dombrowski Y et al. (2009) Vitamin D analogs differentially control antimicrobial peptide/''alarmin'' expression in psoriasis. PLoS One 4:e6340
    • (2009) PLoS One , vol.4
    • Peric, M.1    Koglin, S.2    Dombrowski, Y.3
  • 101
    • 79960304516 scopus 로고    scopus 로고
    • Wound healing activity of the human antimicrobial peptide LL37
    • Ramos R, Silva JP, Rodrigues AC et al. (2011) Wound healing activity of the human antimicrobial peptide LL37. Peptides 32:1469-76
    • (2011) Peptides , vol.32 , pp. 1469-1476
    • Ramos, R.1    Silva, J.P.2    Rodrigues, A.C.3
  • 102
    • 79961064178 scopus 로고    scopus 로고
    • Modulation of human {beta}-defensin-1 (hBD-1 in plasmacytoid dendritic cells (PDC) monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity
    • Ryan LK, Dai J, Yin Z et al. (2011) Modulation of human {beta}-defensin-1 (hBD-1) in plasmacytoid dendritic cells (PDC), monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity. J Leukoc Biol 90:343-56
    • (2011) J Leukoc Biol , vol.90 , pp. 343-356
    • Ryan, L.K.1    Dai, J.2    Yin, Z.3
  • 103
    • 0037417311 scopus 로고    scopus 로고
    • Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
    • DOI 10.1038/nature01520
    • Salzman NH, Ghosh D, Huttner KM et al. (2003) Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature 422:522-6 (Pubitemid 36433647)
    • (2003) Nature , vol.422 , Issue.6931 , pp. 522-526
    • Salzman, N.H.1    Ghosh, D.2    Huttner, K.M.3    Paterson, Y.4    Bevins, C.L.5
  • 104
    • 33947482744 scopus 로고
    • Gramicidin A. V. The structure of valine-and isoleucine-gramicidin A
    • Sarges R, Witkop B (1965a) Gramicidin A. V. The structure of valine-and isoleucine-gramicidin A. J Am Chem Soc 87:2011-20
    • (1965) J Am Chem Soc , vol.87 , pp. 2011-2020
    • Sarges, R.1    Witkop, B.2
  • 105
    • 1542463393 scopus 로고
    • Gramicidin. Vii. The structure of valine-and isoleucine-gramicidin B
    • Sarges R, Witkop B (1965b) Gramicidin. Vii. The structure of valine-and isoleucine-gramicidin B. J Am Chem Soc 87:2027-30
    • (1965) J Am Chem Soc , vol.87 , pp. 2027-2030
    • Sarges, R.1    Witkop, B.2
  • 106
    • 0013411037 scopus 로고
    • Gramicidin. Viii. The structure of valine-and isoleucine-gramicidin C
    • Sarges R, Witkop B (1965c) Gramicidin. Viii. The structure of valine-and isoleucine-gramicidin C. Biochemistry 4:2491-4
    • (1965) Biochemistry , vol.4 , pp. 2491-2494
    • Sarges, R.1    Witkop, B.2
  • 109
    • 0035198723 scopus 로고    scopus 로고
    • Dermcidin: A novel human antibiotic peptide secreted by sweat glands
    • Schittek B, Hipfel R, Sauer B et al. (2001) Dermcidin: A novel human antibiotic peptide secreted by sweat glands. Nat Immunol 2:1133-7
    • (2001) Nat Immunol , vol.2 , pp. 1133-1147
    • Schittek, B.1    Hipfel, R.2    Sauer, B.3
  • 110
    • 78751653584 scopus 로고    scopus 로고
    • Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1
    • Schroeder BO, Wu Z, Nuding S et al. (2011) Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1. Nature 469:419-23
    • (2011) Nature , vol.469 , pp. 419-423
    • Schroeder, B.O.1    Wu, Z.2    Nuding, S.3
  • 112
    • 0021846352 scopus 로고
    • Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils
    • Selsted ME, Brown DM, DeLange RJ et al. (1985) Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem 260:4579-84 (Pubitemid 15034589)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.8 , pp. 4579-4584
    • Selsted, M.E.1    Brown, D.M.2    DeLange, R.J.3
  • 113
    • 0021142387 scopus 로고
    • Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes
    • Selsted ME, Szklarek D, Lehrer RI (1984) Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun 45:150-4 (Pubitemid 14078932)
    • (1984) Infection and Immunity , vol.45 , Issue.1 , pp. 150-154
    • Selsted, M.E.1    Szklarek, D.2    Lehrer, R.I.3
  • 115
    • 0035877995 scopus 로고    scopus 로고
    • Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3
    • Sorensen OE, Follin P, Johnsen AH et al. (2001) Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 97:3951-9
    • (2001) Blood , vol.97 , pp. 3951-3959
    • Sorensen, O.E.1    Follin, P.2    Johnsen, A.H.3
  • 116
    • 0019386682 scopus 로고
    • Sequence and specificity of two antibacterial proteins involved in insect immunity
    • DOI 10.1038/292246a0
    • Steiner H, Hultmark D, Engstrom A et al. (1981) Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292:246-8 (Pubitemid 11001840)
    • (1981) Nature , vol.292 , Issue.5820 , pp. 246-248
    • Steiner, H.1    Hultmark, D.2    Engstrom, A.3
  • 118
    • 84857058762 scopus 로고
    • Some properties of an immune factor isolated from the blood of actively immunized wax moth larvae
    • Stephens JM, Marshall JH (1962) Some properties of an immune factor isolated from the blood of actively immunized wax moth larvae. Can J Microbiol 8:719-25
    • (1962) Can J Microbiol , vol.8 , pp. 719-725
    • Stephens, J.M.1    Marshall, J.H.2
  • 119
    • 0001127084 scopus 로고
    • Bactericidal and fungicidal properties of a crystalline protein isolated from unbleached wheat flour
    • Stuart LS, Harris TH (1942) Bactericidal and fungicidal properties of a crystalline protein isolated from unbleached wheat flour. Cereal Chem 19:288-300
    • (1942) Cereal Chem , vol.19 , pp. 288-300
    • Stuart, L.S.1    Harris, T.H.2
  • 120
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
    • Takeuchi O, Hoshino K, Akira S (2000) Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J Immunol 165:5392-6
    • (2000) J Immunol , vol.165 , pp. 5392-5396
    • Takeuchi, O.1    Hoshino, K.2    Akira, S.3
  • 121
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alphadefensins
    • Tang YQ, Yuan J, Osapay G et al. (1999) A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alphadefensins. Science 286:498-502
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1    Yuan, J.2    Osapay, G.3
  • 122
    • 1042290514 scopus 로고    scopus 로고
    • Hagfish intestinal antimicrobial peptides are ancient cathelicidins
    • DOI 10.1016/j.peptides.2003.08.024
    • Uzzell T, Stolzenberg ED, Shinnar AE et al. (2003) Hagfish intestinal antimicrobial peptides are ancient cathelicidins. Peptides 24:1655-67 (Pubitemid 38198073)
    • (2003) Peptides , vol.24 , Issue.11 , pp. 1655-1667
    • Uzzell, T.1    Stolzenberg, E.D.2    Shinnar, A.E.3    Zasloff, M.4
  • 125
    • 52449125862 scopus 로고    scopus 로고
    • Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics
    • Wang Y, Hong J, Liu X et al. (2008) Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. PLoS One 3:e3217
    • (2008) PLoS One , vol.3
    • Wang, Y.1    Hong, J.2    Liu, X.3
  • 126
    • 78651383015 scopus 로고    scopus 로고
    • Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways
    • Wanke I, Steffen H, Christ C et al. (2011) Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways. J Invest Dermatol 131:382-90
    • (2011) J Invest Dermatol , vol.131 , pp. 382-390
    • Wanke, I.1    Steffen, H.2    Christ, C.3
  • 127
    • 78249233244 scopus 로고    scopus 로고
    • Antimicrobial peptides: The ancient arm of the human immune system
    • Wiesner J, Vilcinskas A (2010) Antimicrobial peptides: The ancient arm of the human immune system. Virulence 1:440-64
    • (2010) Virulence , vol.1 , pp. 440-464
    • Wiesner, J.1    Vilcinskas, A.2
  • 129
    • 77958085274 scopus 로고    scopus 로고
    • Describing the mechanism of antimicrobial Peptide action with the interfacial activity model
    • Wimley WC (2010) Describing the mechanism of antimicrobial Peptide action with the interfacial activity model. ACS Chem Biol 5:905-17
    • (2010) ACS Chem Biol , vol.5 , pp. 905-917
    • Wimley, W.C.1
  • 131
    • 33746299143 scopus 로고    scopus 로고
    • Antimicrobial activities of human β-defensins against Bacillus species
    • DOI 10.1016/j.ijantimicag.2006.02.021, PII S0924857906001828
    • Yadava P, Zhang C, Sun J et al. (2006) Antimicrobial activities of human betadefensins against Bacillus species. Int J Antimicrob Agents 28:132-7 (Pubitemid 44108607)
    • (2006) International Journal of Antimicrobial Agents , vol.28 , Issue.2 , pp. 132-137
    • Yadava, P.1    Zhang, C.2    Sun, J.3    Hughes, J.A.4
  • 133
    • 38549098276 scopus 로고    scopus 로고
    • Antimicrobial peptides in human skin disease
    • DOI 10.1684/ejd.2008.0304
    • Yamasaki K, Gallo RL (2008) Antimicrobial peptides in human skin disease. Eur J Dermatol 18:11-21 (Pubitemid 351158166)
    • (2008) European Journal of Dermatology , vol.18 , Issue.1 , pp. 11-21
    • Yamasaki, K.1    Gallo, R.L.2
  • 134
    • 79951516747 scopus 로고    scopus 로고
    • TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes
    • Yamasaki K, Kanada K, Macleod DT et al. (2010) TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol 131:688-9
    • (2010) J Invest Dermatol , vol.131 , pp. 688-689
    • Yamasaki, K.1    Kanada, K.2    Macleod, D.T.3
  • 136
    • 2542480000 scopus 로고    scopus 로고
    • Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense
    • DOI 10.1146/annurev.immunol.22.012703.104603
    • Yang D, Biragyn A, Hoover DM et al. (2004) Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense. Annu Rev Immunol 22:181-215 (Pubitemid 38680422)
    • (2004) Annual Review of Immunology , vol.22 , pp. 181-215
    • Yang, D.1    Biragyn, A.2    Hoover, D.M.3    Lubkowski, J.4    Oppenheim, J.J.5
  • 137
    • 2142653566 scopus 로고    scopus 로고
    • Differential Regulation of β-Defensin Gene Expression during Cryptosporidium parvum Infection
    • DOI 10.1128/IAI.72.5.2772-2779.2004
    • Zaalouk TK, Bajaj-Elliott M, George JT et al. (2004) Differential regulation of beta-defensin gene expression during Cryptosporidium parvum infection. Infect Immun 72:2772-9 (Pubitemid 38542405)
    • (2004) Infection and Immunity , vol.72 , Issue.5 , pp. 2772-2779
    • Zaalouk, T.K.1    Bajaj-Elliott, M.2    George, J.T.3    McDonald, V.4
  • 138
    • 0037960231 scopus 로고    scopus 로고
    • Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence
    • DOI 10.1046/j.1523-1747.2003.12132.x
    • Zaiou M, Nizet V, Gallo RL (2003) Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol 120:810-6 (Pubitemid 36529083)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.5 , pp. 810-816
    • Zaiou, M.1    Nizet, V.2    Gallo, R.L.3
  • 139
    • 0842326097 scopus 로고    scopus 로고
    • Cathelicidins, multifunctional peptides of the innate immunity
    • DOI 10.1189/jlb.0403147
    • Zanetti M (2004) Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc Biol 75:39-48 (Pubitemid 38166778)
    • (2004) Journal of Leukocyte Biology , vol.75 , Issue.1 , pp. 39-48
    • Zanetti, M.1
  • 140
    • 0027472180 scopus 로고
    • The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics
    • Zanetti M, Del Sal G, Storici P et al. (1993) The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics. J Biol Chem 268:522-6 (Pubitemid 23021353)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.1 , pp. 522-526
    • Zanetti, M.1    Del Sal, G.2    Storici, P.3    Schneider, C.4    Romeo, D.5
  • 141
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
    • Zanetti M, Gennaro R, Romeo D (1995) Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 374:1-5
    • (1995) FEBS Lett , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 142
    • 71949105323 scopus 로고    scopus 로고
    • Constitutive expression of the antimicrobial peptide RNase 7 is associated with Staphylococcus aureus infection of the skin
    • Zanger P, Holzer J, Schleucher R et al. (2009) Constitutive expression of the antimicrobial peptide RNase 7 is associated with Staphylococcus aureus infection of the skin. J Infect Dis 200:1907-15
    • (2009) J Infect Dis , vol.200 , pp. 1907-1915
    • Zanger, P.1    Holzer, J.2    Schleucher, R.3
  • 143
    • 0000255408 scopus 로고
    • Antibacterial and enzymic basic proteins from leukocyte lysosomes: Separation and identification
    • Zeya HI, Spitznagel JK (1963) Antibacterial and enzymic basic proteins from leukocyte lysosomes: Separation and identification. Science 142:1085-7
    • (1963) Science , vol.142 , pp. 1085-1087
    • Zeya, H.I.1    Spitznagel, J.K.2
  • 144
    • 52049112301 scopus 로고    scopus 로고
    • Identification and characterization of novel reptile cathelicidins from elapid snakes
    • Zhao H, Gan TX, Liu XD et al. (2008) Identification and characterization of novel reptile cathelicidins from elapid snakes. Peptides 29:1685-91
    • (2008) Peptides , vol.29 , pp. 1685-1691
    • Zhao, H.1    Gan, T.X.2    Liu, X.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.