Dual functions of the human antimicrobial peptide LL-37-Target membrane perturbation and host cell cargo delivery

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 12, 2010, Pages 2201-2208

  Zhang, Xuan ^a,d   Oglȩcka, Kamila ^a,d   Sandgren, Staffan ^b   Belting, Mattias ^b   Esbjörner, Elin K ^c,e   Nordén, Bengt ^c   Gräslund, Astrid ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antimicrobial peptide; Calcein leakage; CD; Confocal microscopy; Heparan sulphate; LD; LL 37

Indexed keywords

2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHOGLYCEROL; AMPHOLYTE; CALCEIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; HEPARAN SULFATE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANISOTROPY; ARTICLE; CELL TRANSPORT; CIRCULAR DICHROISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; EUKARYOTIC CELL; HUMAN; LIPID BILAYER; MEMBRANE DAMAGE; MEMBRANE FLUIDITY; POLARIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; STEADY STATE; TRANSPORT VESICLE;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CHOLESTEROL; COS CELLS; DRUG DELIVERY SYSTEMS; FLUORESCEINS; FLUORESCENT DYES; HUMANS; OLIGONUCLEOTIDES; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; PROTEIN STRUCTURE, SECONDARY; UNILAMELLAR LIPOSOMES;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 77958124580     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2009.12.011     Document Type: Article

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