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Volumn 591, Issue 15, 2013, Pages 3709-3723

Tumour necrosis factor-α-induced loss of intestinal barrier function requires TNFR1 and TNFR2 signalling in a mouse model of total parenteral nutrition

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN; ETANERCEPT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYOSIN LIGHT CHAIN KINASE; OCCLUDIN; PROTEIN ZO1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UVOMORULIN;

EID: 84880986819     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.253518     Document Type: Article
Times cited : (66)

References (89)
  • 1
    • 32544432516 scopus 로고    scopus 로고
    • Tight junctions: molecular architecture and function
    • Aijaz S, Balda MS & Matter K (2006). Tight junctions: molecular architecture and function. Int Rev Cytol 248, 261-298.
    • (2006) Int Rev Cytol , vol.248 , pp. 261-298
    • Aijaz, S.1    Balda, M.S.2    Matter, K.3
  • 2
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1β-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K & Ma TY (2008). Mechanism of IL-1β-induced increase in intestinal epithelial tight junction permeability. J Immunol 180, 5653-5661.
    • (2008) J Immunol , vol.180 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 3
    • 78149291807 scopus 로고    scopus 로고
    • IL-1β-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-κB pathway
    • Al-Sadi R, Ye D, Said HM & Ma TY (2010). IL-1β-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-κB pathway. Am J Pathol 177, 2310-2322.
    • (2010) Am J Pathol , vol.177 , pp. 2310-2322
    • Al-Sadi, R.1    Ye, D.2    Said, H.M.3    Ma, T.Y.4
  • 4
    • 78649730159 scopus 로고    scopus 로고
    • TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling
    • Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M, Fromm M & Schulzke JD (2010). TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling. J Cell Sci 123, 4145-4155.
    • (2010) J Cell Sci , vol.123 , pp. 4145-4155
    • Amasheh, M.1    Fromm, A.2    Krug, S.M.3    Amasheh, S.4    Andres, S.5    Zeitz, M.6    Fromm, M.7    Schulzke, J.D.8
  • 5
    • 70350648021 scopus 로고    scopus 로고
    • Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: a novel model for studying the pathomechanisms of inflammatory bowel disease cytokines
    • Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M & Schulzke JD (2009). Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: a novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand J Gastroenterol 44, 1226-1235.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 1226-1235
    • Amasheh, M.1    Grotjohann, I.2    Amasheh, S.3    Fromm, A.4    Söderholm, J.D.5    Zeitz, M.6    Fromm, M.7    Schulzke, J.D.8
  • 7
    • 58249085436 scopus 로고    scopus 로고
    • Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
    • Arrieta MC, Madsen K, Doyle J & Meddings J (2009). Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse. Gut 58, 41-48.
    • (2009) Gut , vol.58 , pp. 41-48
    • Arrieta, M.C.1    Madsen, K.2    Doyle, J.3    Meddings, J.4
  • 8
    • 0033021497 scopus 로고    scopus 로고
    • Anti-TNF strategies in Crohn's disease: mechanisms, clinical effects, indications
    • Baert FJ & Rutgeerts PR (1999). Anti-TNF strategies in Crohn's disease: mechanisms, clinical effects, indications. Int J Colorectal Dis 14, 47-51.
    • (1999) Int J Colorectal Dis , vol.14 , pp. 47-51
    • Baert, F.J.1    Rutgeerts, P.R.2
  • 9
    • 0001342423 scopus 로고    scopus 로고
    • Medical therapies for ulcerative colitis and Crohn's disease
    • Baert FJ & Rutgeerts PJ (2000). Medical therapies for ulcerative colitis and Crohn's disease. Curr Gastroenterol Rep 2, 446-450.
    • (2000) Curr Gastroenterol Rep , vol.2 , pp. 446-450
    • Baert, F.J.1    Rutgeerts, P.J.2
  • 10
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB-a pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ & Karin M (1997). Nuclear factor-κB-a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336, 1066-1071.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 12
    • 0033011210 scopus 로고    scopus 로고
    • Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease
    • Brown GR, Lindberg G, Meddings J, Silva M, Beutler B & Thiele D (1999). Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease. Gastroenterology 116, 593-601.
    • (1999) Gastroenterology , vol.116 , pp. 593-601
    • Brown, G.R.1    Lindberg, G.2    Meddings, J.3    Silva, M.4    Beutler, B.5    Thiele, D.6
  • 15
    • 42149154920 scopus 로고    scopus 로고
    • Human stanniocalcin-1 blocks TNF-α-induced monolayer permeability in human coronary artery endothelial cells
    • Chen C, Jamaluddin MS, Yan S, Sheikh-Hamad D & Yao Q (2008). Human stanniocalcin-1 blocks TNF-α-induced monolayer permeability in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol 28, 906-912.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 906-912
    • Chen, C.1    Jamaluddin, M.S.2    Yan, S.3    Sheikh-Hamad, D.4    Yao, Q.5
  • 16
    • 84859992839 scopus 로고    scopus 로고
    • Myosin light chain kinase mediates intestinal barrier disruption following burn injury
    • Chen C, Wang P, Su Q, Wang S & Wang F (2012). Myosin light chain kinase mediates intestinal barrier disruption following burn injury. PLoS One 7, e34946.
    • (2012) PLoS One , vol.7
    • Chen, C.1    Wang, P.2    Su, Q.3    Wang, S.4    Wang, F.5
  • 18
    • 33749428028 scopus 로고    scopus 로고
    • Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo
    • Clayburgh DR, Musch MW, Leitges M, Fu YX & Turner JR (2006). Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. J Clin Invest 116, 2682-2694.
    • (2006) J Clin Invest , vol.116 , pp. 2682-2694
    • Clayburgh, D.R.1    Musch, M.W.2    Leitges, M.3    Fu, Y.X.4    Turner, J.R.5
  • 20
    • 84862853385 scopus 로고    scopus 로고
    • Myosin light chain kinase: pulling the strings of epithelial tight junction function
    • Cunningham KE & Turner JR (2012). Myosin light chain kinase: pulling the strings of epithelial tight junction function. Ann N Y Acad Sci 1258, 34-42.
    • (2012) Ann N Y Acad Sci , vol.1258 , pp. 34-42
    • Cunningham, K.E.1    Turner, J.R.2
  • 21
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E & Karin M (1997). A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388, 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 23
    • 70449466824 scopus 로고    scopus 로고
    • The tight junction in inflammatory disease: communication breakdown
    • Edelblum KL & Turner JR (2009). The tight junction in inflammatory disease: communication breakdown. Curr Opin Pharmacol 9, 715-720.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 715-720
    • Edelblum, K.L.1    Turner, J.R.2
  • 24
    • 84862871038 scopus 로고    scopus 로고
    • Total parenteral nutrition (TPN)-associated atrophy is associated with loss of intestinal epithelial cell (EC) migration: modulation of action by epidermal growth factor (EGF) and glucagon-like peptide-2 (GLP-2)
    • S-170-S-171
    • Feng Y, Holst J & Teitelbaum D (2011). Total parenteral nutrition (TPN)-associated atrophy is associated with loss of intestinal epithelial cell (EC) migration: modulation of action by epidermal growth factor (EGF) and glucagon-like peptide-2 (GLP-2). Gastroenterology 140, S-170-S-171.
    • (2011) Gastroenterology , vol.140
    • Feng, Y.1    Holst, J.2    Teitelbaum, D.3
  • 25
    • 84862836971 scopus 로고    scopus 로고
    • Loss of enteral nutrition in a mouse model results in intestinal epithelial barrier dysfunction
    • Feng Y, Ralls MW, Xiao W, Miyasaka E, Herman RS & Teitelbaum DH (2012). Loss of enteral nutrition in a mouse model results in intestinal epithelial barrier dysfunction. Ann N Y Acad Sci 1258, 71-77.
    • (2012) Ann N Y Acad Sci , vol.1258 , pp. 71-77
    • Feng, Y.1    Ralls, M.W.2    Xiao, W.3    Miyasaka, E.4    Herman, R.S.5    Teitelbaum, D.H.6
  • 26
    • 59649128714 scopus 로고    scopus 로고
    • Dissociation of E-cadherin and β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy
    • Feng Y, Sun X, Yang H & Teitelbaum DH (2009). Dissociation of E-cadherin and β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy. J Physiol 587, 641-654.
    • (2009) J Physiol , vol.587 , pp. 641-654
    • Feng, Y.1    Sun, X.2    Yang, H.3    Teitelbaum, D.H.4
  • 27
    • 84855304103 scopus 로고    scopus 로고
    • Epidermal growth factor/TNF-α transactivation modulates epithelial cell proliferation and apoptosis in a mouse model of parenteral nutrition
    • G236-G249
    • Feng Y & Teitelbaum DH (2012). Epidermal growth factor/TNF-α transactivation modulates epithelial cell proliferation and apoptosis in a mouse model of parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 302, G236-G249.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302
    • Feng, Y.1    Teitelbaum, D.H.2
  • 28
    • 47349097005 scopus 로고    scopus 로고
    • Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis
    • Fries W, Muja C, Crisafulli C, Costantino G, Longo G, Cuzzocrea S & Mazzon E (2008). Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis. Int J Med Sci 5, 169-180.
    • (2008) Int J Med Sci , vol.5 , pp. 169-180
    • Fries, W.1    Muja, C.2    Crisafulli, C.3    Costantino, G.4    Longo, G.5    Cuzzocrea, S.6    Mazzon, E.7
  • 29
    • 0035897412 scopus 로고    scopus 로고
    • Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells
    • Furuse M, Furuse K, Sasaki H & Tsukita S (2001). Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol 153, 263-272.
    • (2001) J Cell Biol , vol.153 , pp. 263-272
    • Furuse, M.1    Furuse, K.2    Sasaki, H.3    Tsukita, S.4
  • 30
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • S81-S96
    • Ghosh S & Karin M (2002). Missing pieces in the NF-κB puzzle. Cell 109 Suppl, S81-S96.
    • (2002) Cell , vol.109 , Issue.SUPPL
    • Ghosh, S.1    Karin, M.2
  • 31
    • 84863015820 scopus 로고    scopus 로고
    • Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation
    • Gilbert S, Zhang R, Denson L, Moriggl R, Steinbrecher K, Shroyer N, Lin J & Han X (2012). Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation. EMBO Mol Med 4, 109-124.
    • (2012) EMBO Mol Med , vol.4 , pp. 109-124
    • Gilbert, S.1    Zhang, R.2    Denson, L.3    Moriggl, R.4    Steinbrecher, K.5    Shroyer, N.6    Lin, J.7    Han, X.8
  • 34
    • 79952250893 scopus 로고    scopus 로고
    • Total parenteral-nutrition-mediated dendritic-cell activation and infiltration into the small intestine in a rat model
    • Hagiwara S, Iwasaka H, Kusaka J, Asai N, Uchida T & Noguchi T (2011). Total parenteral-nutrition-mediated dendritic-cell activation and infiltration into the small intestine in a rat model. J Anesth 25, 57-64.
    • (2011) J Anesth , vol.25 , pp. 57-64
    • Hagiwara, S.1    Iwasaka, H.2    Kusaka, J.3    Asai, N.4    Uchida, T.5    Noguchi, T.6
  • 35
    • 84881012788 scopus 로고    scopus 로고
    • HCUPnet National Center for Health Statistics Data on PN and EN Use
    • HCUPnet (2010). National Center for Health Statistics Data on PN and EN Use. http://hcupnet.ahrq.gov/
    • (2010)
  • 36
    • 79955504880 scopus 로고    scopus 로고
    • Transforming growth factor-β, a whey protein component, strengthens the intestinal barrier by upregulating claudin-4 in HT-29/B6 cells
    • Hering NA, Andres S, Fromm A, van Tol EA, Amasheh M, Mankertz J, Fromm M & Schulzke JD (2011). Transforming growth factor-β, a whey protein component, strengthens the intestinal barrier by upregulating claudin-4 in HT-29/B6 cells. J Nutr 141, 783-789.
    • (2011) J Nutr , vol.141 , pp. 783-789
    • Hering, N.A.1    Andres, S.2    Fromm, A.3    van Tol, E.A.4    Amasheh, M.5    Mankertz, J.6    Fromm, M.7    Schulzke, J.D.8
  • 37
    • 33646792959 scopus 로고    scopus 로고
    • Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns
    • Holmes JL, Van Itallie CM, Rasmussen JE & Anderson JM (2006). Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns. Gene Expr Patterns 6, 581-588.
    • (2006) Gene Expr Patterns , vol.6 , pp. 581-588
    • Holmes, J.L.1    Van Itallie, C.M.2    Rasmussen, J.E.3    Anderson, J.M.4
  • 38
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to α catenin and actin filaments
    • Itoh M, Nagafuchi A, Moroi S & Tsukita S (1997). Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to α catenin and actin filaments. J Cell Biol 138, 181-192.
    • (1997) J Cell Biol , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 39
    • 84855769712 scopus 로고    scopus 로고
    • Small intestine mucosal immune system response to injury and the impact of parenteral nutrition
    • Jonker MA, Hermsen JL, Sano Y, Heneghan AF, Lan J & Kudsk KA (2012). Small intestine mucosal immune system response to injury and the impact of parenteral nutrition. Surgery 151, 278-286.
    • (2012) Surgery , vol.151 , pp. 278-286
    • Jonker, M.A.1    Hermsen, J.L.2    Sano, Y.3    Heneghan, A.F.4    Lan, J.5    Kudsk, K.A.6
  • 41
    • 0032190430 scopus 로고    scopus 로고
    • Alteration of the intestinal intraepithelial lymphocytes during total parenteral nutrition
    • Kiristioglu I & Teitelbaum DH (1998). Alteration of the intestinal intraepithelial lymphocytes during total parenteral nutrition. J Surg Res 79, 91-96.
    • (1998) J Surg Res , vol.79 , pp. 91-96
    • Kiristioglu, I.1    Teitelbaum, D.H.2
  • 48
    • 0021251275 scopus 로고
    • Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships
    • Marcial MA, Carlson SL & Madara JL (1984). Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships. J Membr Biol 80, 59-70.
    • (1984) J Membr Biol , vol.80 , pp. 59-70
    • Marcial, M.A.1    Carlson, S.L.2    Madara, J.L.3
  • 49
    • 0028130351 scopus 로고
    • Intestinal permeability in patients with Crohn's disease
    • Meddings JB, Sutherland LR & May GR (1994). Intestinal permeability in patients with Crohn's disease. Gut 35, 1675-1676.
    • (1994) Gut , vol.35 , pp. 1675-1676
    • Meddings, J.B.1    Sutherland, L.R.2    May, G.R.3
  • 51
    • 0031944250 scopus 로고    scopus 로고
    • Molecular architecture of tight junctions
    • Mitic LL & Anderson JM (1998). Molecular architecture of tight junctions. Annu Rev Physiol 60, 121-142.
    • (1998) Annu Rev Physiol , vol.60 , pp. 121-142
    • Mitic, L.L.1    Anderson, J.M.2
  • 52
    • 0033851771 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins
    • G250-G254
    • Mitic LL, Van Itallie CM & Anderson JM (2000). Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 279, G250-G254.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Mitic, L.L.1    Van Itallie, C.M.2    Anderson, J.M.3
  • 53
    • 79952076124 scopus 로고    scopus 로고
    • Anti-TNF therapy using etanercept suppresses degenerative and inflammatory changes in skeletal muscle of older SJL/J mice
    • Nemoto H, Konno S, Sugimoto H, Nakazora H, Nomoto N, Murata M, Kitazono H & Fujioka T (2011). Anti-TNF therapy using etanercept suppresses degenerative and inflammatory changes in skeletal muscle of older SJL/J mice. Exp Mol Pathol 90, 264-270.
    • (2011) Exp Mol Pathol , vol.90 , pp. 264-270
    • Nemoto, H.1    Konno, S.2    Sugimoto, H.3    Nakazora, H.4    Nomoto, N.5    Murata, M.6    Kitazono, H.7    Fujioka, T.8
  • 54
    • 77649302757 scopus 로고    scopus 로고
    • Glutamine prevents total parenteral nutrition-associated changes to intraepithelial lymphocyte phenotype and function: a potential mechanism for the preservation of epithelial barrier function
    • Nose K, Yang H, Sun X, Nose S, Koga H, Feng Y, Miyasaka E & Teitelbaum DH (2010). Glutamine prevents total parenteral nutrition-associated changes to intraepithelial lymphocyte phenotype and function: a potential mechanism for the preservation of epithelial barrier function. J Interferon Cytokine Res 30, 67-80.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 67-80
    • Nose, K.1    Yang, H.2    Sun, X.3    Nose, S.4    Koga, H.5    Feng, Y.6    Miyasaka, E.7    Teitelbaum, D.H.8
  • 56
    • 84864421205 scopus 로고    scopus 로고
    • Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway
    • Petecchia L, Sabatini F, Usai C, Caci E, Varesio L & Rossi GA (2012). Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway. Lab Invest 92, 1140-1148.
    • (2012) Lab Invest , vol.92 , pp. 1140-1148
    • Petecchia, L.1    Sabatini, F.2    Usai, C.3    Caci, E.4    Varesio, L.5    Rossi, G.A.6
  • 57
    • 33845263659 scopus 로고    scopus 로고
    • Epithelial electrical resistance as a measure of permeability changes in pediatric duodenal biopsies
    • Reims A, Strandvik B & Sjövall H (2006). Epithelial electrical resistance as a measure of permeability changes in pediatric duodenal biopsies. J Pediatr Gastroenterol Nutr 43, 619-623.
    • (2006) J Pediatr Gastroenterol Nutr , vol.43 , pp. 619-623
    • Reims, A.1    Strandvik, B.2    Sjövall, H.3
  • 58
    • 0033607313 scopus 로고    scopus 로고
    • The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus
    • RE1
    • Rothwarf DM & Karin M (1999). The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus. Sci STKE 1999, RE1.
    • (1999) Sci STKE , vol.1999
    • Rothwarf, D.M.1    Karin, M.2
  • 59
    • 78651070199 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase N2 regulates TNFα-induced signalling and cytokine secretion in human intestinal epithelial cells
    • Scharl M, McCole DF, Weber A, Vavricka SR, Frei P, Kellermeier S, Pesch T, Fried M & Rogler G (2011). Protein tyrosine phosphatase N2 regulates TNFα-induced signalling and cytokine secretion in human intestinal epithelial cells. Gut 60, 189-197.
    • (2011) Gut , vol.60 , pp. 189-197
    • Scharl, M.1    McCole, D.F.2    Weber, A.3    Vavricka, S.R.4    Frei, P.5    Kellermeier, S.6    Pesch, T.7    Fried, M.8    Rogler, G.9
  • 61
    • 34250190636 scopus 로고    scopus 로고
    • LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms
    • Schwarz BT, Wang F, Shen L, Clayburgh DR, Su L, Wang Y, Fu YX & Turner JR (2007). LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology 132, 2383-2394.
    • (2007) Gastroenterology , vol.132 , pp. 2383-2394
    • Schwarz, B.T.1    Wang, F.2    Shen, L.3    Clayburgh, D.R.4    Su, L.5    Wang, Y.6    Fu, Y.X.7    Turner, J.R.8
  • 62
    • 84862834603 scopus 로고    scopus 로고
    • Tight junctions on the move: molecular mechanisms for epithelial barrier regulation
    • Shen L (2012). Tight junctions on the move: molecular mechanisms for epithelial barrier regulation. Ann N Y Acad Sci 1258, 9-18.
    • (2012) Ann N Y Acad Sci , vol.1258 , pp. 9-18
    • Shen, L.1
  • 64
    • 25144442798 scopus 로고    scopus 로고
    • Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo
    • Shifflett DE, Clayburgh DR, Koutsouris A, Turner JR & Hecht GA (2005). Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo. Lab Invest 85, 1308-1324.
    • (2005) Lab Invest , vol.85 , pp. 1308-1324
    • Shifflett, D.E.1    Clayburgh, D.R.2    Koutsouris, A.3    Turner, J.R.4    Hecht, G.A.5
  • 66
    • 0036652393 scopus 로고    scopus 로고
    • Focus on "Claudins create charge-selective channels in the paracellular pathway between epithelial cells"
    • C29-C30
    • Spring KR (2002). Focus on "Claudins create charge-selective channels in the paracellular pathway between epithelial cells". Am J Physiol Cell Physiol 283, C29-C30.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Spring, K.R.1
  • 67
    • 58649090901 scopus 로고    scopus 로고
    • Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
    • Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C & Turner JR (2009). Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 136, 551-563.
    • (2009) Gastroenterology , vol.136 , pp. 551-563
    • Su, L.1    Shen, L.2    Clayburgh, D.R.3    Nalle, S.C.4    Sullivan, E.A.5    Meddings, J.B.6    Abraham, C.7    Turner, J.R.8
  • 69
  • 70
    • 80052400212 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium
    • Suzuki T, Yoshinaga N & Tanabe S (2011). Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium. J Biol Chem 286, 31263-31271.
    • (2011) J Biol Chem , vol.286 , pp. 31263-31271
    • Suzuki, T.1    Yoshinaga, N.2    Tanabe, S.3
  • 73
    • 0030986715 scopus 로고    scopus 로고
    • Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells
    • Taylor CT, Murphy A, Kelleher D & Baird AW (1997). Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells. Gut 40, 634-640.
    • (1997) Gut , vol.40 , pp. 634-640
    • Taylor, C.T.1    Murphy, A.2    Kelleher, D.3    Baird, A.W.4
  • 74
    • 0035013499 scopus 로고    scopus 로고
    • Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability
    • Van Itallie C, Rahner C & Anderson JM (2001). Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability. J Clin Invest 107, 1319-1327.
    • (2001) J Clin Invest , vol.107 , pp. 1319-1327
    • Van Itallie, C.1    Rahner, C.2    Anderson, J.M.3
  • 75
    • 0034937803 scopus 로고    scopus 로고
    • Down-regulation of occludin expression in astrocytes by tumour necrosis factor (TNF) is mediated via TNF type-1 receptor and nuclear factor-κB activation
    • Wachtel M, Bolliger MF, Ishihara H, Frei K, Bluethmann H & Gloor SM (2001). Down-regulation of occludin expression in astrocytes by tumour necrosis factor (TNF) is mediated via TNF type-1 receptor and nuclear factor-κB activation. J Neurochem 78, 155-162.
    • (2001) J Neurochem , vol.78 , pp. 155-162
    • Wachtel, M.1    Bolliger, M.F.2    Ishihara, H.3    Frei, K.4    Bluethmann, H.5    Gloor, S.M.6
  • 76
    • 13244298599 scopus 로고    scopus 로고
    • Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
    • Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT & Turner JR (2005). Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol 166, 409-419.
    • (2005) Am J Pathol , vol.166 , pp. 409-419
    • Wang, F.1    Graham, W.V.2    Wang, Y.3    Witkowski, E.D.4    Schwarz, B.T.5    Turner, J.R.6
  • 78
    • 84862873626 scopus 로고    scopus 로고
    • TNF-α-induced intestinal epithelial cell shedding: implications for intestinal barrier function
    • Watson AJ & Hughes KR (2012). TNF-α-induced intestinal epithelial cell shedding: implications for intestinal barrier function. Ann N Y Acad Sci 1258, 1-8.
    • (2012) Ann N Y Acad Sci , vol.1258 , pp. 1-8
    • Watson, A.J.1    Hughes, K.R.2
  • 79
    • 77950588683 scopus 로고    scopus 로고
    • Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity
    • Weber CR, Raleigh DR, Su L, Shen L, Sullivan EA, Wang Y & Turner JR (2010). Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem 285, 12037-12046.
    • (2010) J Biol Chem , vol.285 , pp. 12037-12046
    • Weber, C.R.1    Raleigh, D.R.2    Su, L.3    Shen, L.4    Sullivan, E.A.5    Wang, Y.6    Turner, J.R.7
  • 81
    • 0037643663 scopus 로고    scopus 로고
    • Gene alteration of intestinal intraepithelial lymphocytes with administration of total parenteral nutrition
    • Wildhaber BE, Yang H, Tazuke Y & Teitelbaum DH (2003). Gene alteration of intestinal intraepithelial lymphocytes with administration of total parenteral nutrition. J Pediatr Surg 38, 840-843.
    • (2003) J Pediatr Surg , vol.38 , pp. 840-843
    • Wildhaber, B.E.1    Yang, H.2    Tazuke, Y.3    Teitelbaum, D.H.4
  • 82
    • 50149105621 scopus 로고    scopus 로고
    • Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis
    • Yamaoka T, Yan F, Cao H, Hobbs SS, Dise RS, Tong W & Polk DB (2008). Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proc Natl Acad Sci U S A 105, 11772-11777.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11772-11777
    • Yamaoka, T.1    Yan, F.2    Cao, H.3    Hobbs, S.S.4    Dise, R.S.5    Tong, W.6    Polk, D.B.7
  • 83
    • 67249102449 scopus 로고    scopus 로고
    • Enteral versus parenteral nutrition: effect on intestinal barrier function
    • Yang H, Feng Y, Sun X & Teitelbaum DH (2009). Enteral versus parenteral nutrition: effect on intestinal barrier function. Ann N Y Acad Sci 1165, 338-346.
    • (2009) Ann N Y Acad Sci , vol.1165 , pp. 338-346
    • Yang, H.1    Feng, Y.2    Sun, X.3    Teitelbaum, D.H.4
  • 84
    • 0036320133 scopus 로고    scopus 로고
    • Interferon-gamma expression by intraepithelial lymphocytes results in a loss of epithelial barrier function in a mouse model of total parenteral nutrition
    • Yang H, Kiristioglu I, Fan Y, Forbush B, Bishop DK, Antony PA, Zhou H & Teitelbaum DH (2002). Interferon-gamma expression by intraepithelial lymphocytes results in a loss of epithelial barrier function in a mouse model of total parenteral nutrition. Ann Surg 236, 226-234.
    • (2002) Ann Surg , vol.236 , pp. 226-234
    • Yang, H.1    Kiristioglu, I.2    Fan, Y.3    Forbush, B.4    Bishop, D.K.5    Antony, P.A.6    Zhou, H.7    Teitelbaum, D.H.8
  • 85
    • 33846151651 scopus 로고    scopus 로고
    • Intestinal epithelial cell-derived interleukin-7: a mechanism for the alteration of intraepithelial lymphocytes in a mouse model of total parenteral nutrition
    • G84-G91
    • Yang H, Sun X, Haxhija EQ & Teitelbaum DH (2007). Intestinal epithelial cell-derived interleukin-7: a mechanism for the alteration of intraepithelial lymphocytes in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 292, G84-G91.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Yang, H.1    Sun, X.2    Haxhija, E.Q.3    Teitelbaum, D.H.4
  • 86
    • 80053581738 scopus 로고    scopus 로고
    • MicroRNA regulation of intestinal epithelial tight junction permeability
    • Ye D, Guo S, Al-Sadi R & Ma TY (2011). MicroRNA regulation of intestinal epithelial tight junction permeability. Gastroenterology 141, 1323-1333.
    • (2011) Gastroenterology , vol.141 , pp. 1323-1333
    • Ye, D.1    Guo, S.2    Al-Sadi, R.3    Ma, T.Y.4
  • 87
    • 33644981348 scopus 로고    scopus 로고
    • Molecular mechanism of tumor necrosis factor-α modulation of intestinal epithelial tight junction barrier
    • G496-G504
    • Ye D, Ma I & Ma TY (2006). Molecular mechanism of tumor necrosis factor-α modulation of intestinal epithelial tight junction barrier. Am J Physiol Gastrointest Liver Physiol 290, G496-G504.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Ye, D.1    Ma, I.2    Ma, T.Y.3
  • 88
    • 49549104243 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-α-induced regulation of myosin light chain kinase gene activity
    • Ye D & Ma TY (2008). Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-α-induced regulation of myosin light chain kinase gene activity. J Cell Mol Med 12, 1331-1346.
    • (2008) J Cell Mol Med , vol.12 , pp. 1331-1346
    • Ye, D.1    Ma, T.Y.2
  • 89
    • 33845995125 scopus 로고    scopus 로고
    • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
    • Zeissig S, Bürgel N, Günzel D, Richter J, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M & Schulzke JD (2007). Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56, 61-72.
    • (2007) Gut , vol.56 , pp. 61-72
    • Zeissig, S.1    Bürgel, N.2    Günzel, D.3    Richter, J.4    Mankertz, J.5    Wahnschaffe, U.6    Kroesen, A.J.7    Zeitz, M.8    Fromm, M.9    Schulzke, J.D.10


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