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Volumn 12, Issue 7, 2013, Pages 733-746

Combination of adjuvants: The future of vaccine design

Author keywords

adjuvants; ISCOMATRIX adjuvant; Toll like receptor; vaccines

Indexed keywords

AGATOLIMOD; ALPHA TOCOPHEROL; ALUMINUM HYDROXIDE; ALUMINUM PHOSPHATE; ALUMINUM POTASSIUM SULFATE; ANTHRAX VACCINE; AS 01; AS 02; AS 04; AS 15; BCG VACCINE; DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS HAEMOPHILUS INFLUENZAE TYPE B VACCINE; DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS HEPATITIS B VACCINE; DIPHTHERIA PERTUSSIS TETANUS VACCINE; HAEMOPHILUS INFLUENZAE VACCINE; HEPATITIS A VACCINE; HEPATITIS B VACCINE; IMMUNOLOGICAL ADJUVANT; IMMUVAC; INFLUENZA VACCINE; ISA 51; ISCOMATRIX; ISCOPREP; MIFAMURTIDE; MONTANIDE; MONTANIDE ISA 51; PATTERN RECOGNITION RECEPTOR; QS 21; RESIQUIMOD; SIPULEUCEL T; SQUALENE; UNCLASSIFIED DRUG; WART VIRUS VACCINE;

EID: 84880900133     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.2013.811185     Document Type: Review
Times cited : (57)

References (114)
  • 1
    • 77955597687 scopus 로고    scopus 로고
    • Unmet needs in modern vaccinology: Adjuvants to improve the immune response
    • Leroux-Roels G. Unmet needs in modern vaccinology: Adjuvants to improve the immune response. Vaccine 28(Suppl. 3), C25-C36 (2010
    • (2010) Vaccine , vol.28 , Issue.SUPPL. 3
    • Leroux-Roels, G.1
  • 2
    • 77951554477 scopus 로고    scopus 로고
    • Patented cancer vaccines: The promising leads
    • Aurisicchio L, Ciliberto G. Patented cancer vaccines: The promising leads. Expert Opin. Ther. Pat. 20(5), 647-660 (2010
    • (2010) Expert Opin. Ther. Pat , vol.20 , Issue.5 , pp. 647-660
    • Aurisicchio, L.1    Ciliberto, G.2
  • 3
    • 77958513288 scopus 로고    scopus 로고
    • Hepatitis A and hepatitis C viruses: Divergent infection outcomes marked by similarities in induction and evasion of interferon responses
    • Qu L, Lemon SM. Hepatitis A and hepatitis C viruses: Divergent infection outcomes marked by similarities in induction and evasion of interferon responses. Semin. Liver Dis. 30(4), 319-332 (2010
    • (2010) Semin. Liver Dis , vol.30 , Issue.4 , pp. 319-332
    • Qu, L.1    Lemon, S.M.2
  • 4
    • 84864911121 scopus 로고    scopus 로고
    • HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion
    • Marsili G, Remoli AL, Sgarbanti M, Perrotti E, Fragale A, Battistini A. HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion. Cytokine Growth Factor Rev. 23(4-5), 255-270 (2012
    • (2012) Cytokine Growth Factor Rev , vol.23 , Issue.4-5 , pp. 255-270
    • Marsili, G.1    Remoli, A.L.2    Sgarbanti, M.3    Perrotti, E.4    Fragale, A.5    Battistini, A.6
  • 5
    • 84874068498 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity
    • Singh Y, Kaul V, Mehra A et al. Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity. J. Biol. Chem. 288(7), 5056-5061 (2013
    • (2013) J. Biol. Chem , vol.288 , Issue.7 , pp. 5056-5061
    • Singh, Y.1    Kaul, V.2    Mehra, A.3
  • 6
    • 84856003520 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells
    • Blomgran R, Desvignes L, Briken V, Ernst JD. Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells. Cell Host Microbe 11(1), 81-90 (2012
    • (2012) Cell Host Microbe , vol.11 , Issue.1 , pp. 81-90
    • Blomgran, R.1    Desvignes, L.2    Briken, V.3    Ernst, J.D.4
  • 7
    • 79251572061 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination
    • Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J. Immunol. 186(3), 1627-1637 (2011
    • (2011) J. Immunol , vol.186 , Issue.3 , pp. 1627-1637
    • Woodworth, J.S.1    Shin, D.2    Volman, M.3    Nunes-Alves, C.4    Fortune, S.M.5    Behar, S.M.6
  • 8
    • 34548190506 scopus 로고    scopus 로고
    • Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge
    • Harzstark AL, Small EJ. Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge). Expert Opin. Biol. Ther. 7(8), 1275-1280 (2007
    • (2007) Expert Opin. Biol. Ther , vol.7 , Issue.8 , pp. 1275-1280
    • Harzstark, A.L.1    Small, E.J.2
  • 9
    • 63149126030 scopus 로고    scopus 로고
    • Towards an understanding of the adjuvant action of aluminium
    • Marrack P, McKee AS, Munks MW. Towards an understanding of the adjuvant action of aluminium. Nat. Rev. Immunol. 9(4), 287-293 (2009
    • (2009) Nat. Rev. Immunol , vol.9 , Issue.4 , pp. 287-293
    • Marrack, P.1    McKee, A.S.2    Munks, M.W.3
  • 10
    • 0035925666 scopus 로고    scopus 로고
    • The adjuvanted influenza vaccines with novel adjuvants: Experience with the MF59-Adjuvanted vaccine
    • Podda A. The adjuvanted influenza vaccines with novel adjuvants: Experience with the MF59-Adjuvanted vaccine. Vaccine 19(17-19), 2673-2680 (2001
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2673-2680
    • Podda, A.1
  • 11
    • 51549100095 scopus 로고    scopus 로고
    • Prepandemic influenza vaccine H5N1 (split virion, inactivated, adjuvanted) [Prepandrix a review of its use as an active immunization against influenza A subtype H5N1 virus
    • Carter NJ, Plosker GL. Prepandemic influenza vaccine H5N1 (split virion, inactivated, adjuvanted) [Prepandrix]: A review of its use as an active immunization against influenza A subtype H5N1 virus. BioDrugs 22(5), 279-292 (2008
    • (2008) BioDrugs , vol.22 , Issue.5 , pp. 279-292
    • Carter, N.J.1    Plosker, G.L.2
  • 12
    • 80053596320 scopus 로고    scopus 로고
    • Influenza vaccines: What do we want and how can we get it?
    • Geeraedts F, Huckriede A. Influenza vaccines: What do we want and how can we get it? Adv. Exp. Med. Biol. 780, 161-174 (2011
    • (2011) Adv Exp. Med. Biol , vol.780 , pp. 161-174
    • Geeraedts, F.1    Huckriede, A.2
  • 14
    • 84859020840 scopus 로고    scopus 로고
    • Development and evaluation of AS03, an Adjuvant System containing a-Tocopherol and squalene in an oil-in-water emulsion
    • Garçon N, Vaughn DW, Didierlaurent AM. Development and evaluation of AS03, an Adjuvant System containing a-Tocopherol and squalene in an oil-in-water emulsion. Expert Rev. Vaccines 11(3), 349-366 (2012
    • (2012) Expert Rev. Vaccines , vol.11 , Issue.3 , pp. 349-366
    • Garçon, N.1    Vaughn, D.W.2    Didierlaurent, A.M.3
  • 15
    • 53849128926 scopus 로고    scopus 로고
    • Epaxal: A virosomal vaccine to prevent hepatitis A infection
    • Bovier PA. Epaxal: A virosomal vaccine to prevent hepatitis A infection. Expert Rev. Vaccines 7(8), 1141-1150 (2008
    • (2008) Expert Rev. Vaccines , vol.7 , Issue.8 , pp. 1141-1150
    • Bovier, P.A.1
  • 16
    • 34247234090 scopus 로고    scopus 로고
    • New hepatitis B vaccine formulated with an improved adjuvant system
    • Kundi M. New hepatitis B vaccine formulated with an improved adjuvant system. Expert Rev. Vaccines 6(2), 133-140 (2007
    • (2007) Expert Rev. Vaccines , vol.6 , Issue.2 , pp. 133-140
    • Kundi, M.1
  • 17
    • 84864959795 scopus 로고    scopus 로고
    • Cervarix®: A bivalent vaccine against hpv types 16 and 18 with cross-protection against other high-risk hpv types
    • Szarewski A. Cervarix®: A bivalent vaccine against HPV types 16 and 18, with cross-protection against other high-risk HPV types. Expert Rev. Vaccines 11(6), 645-657 (2012
    • (2012) Expert Rev. Vaccines , vol.11 , Issue.6 , pp. 645-657
    • Szarewski, A.1
  • 18
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: Putting innate immunity to work
    • Coffman RL, Sher A, Seder RA. Vaccine adjuvants: Putting innate immunity to work. Immunity 33(4), 492-503 (2010
    • (2010) Immunity , vol.33 , Issue.4 , pp. 492-503
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 19
    • 79952173864 scopus 로고    scopus 로고
    • Programming the magnitude and persistence of antibody responses with innate immunity
    • Kasturi SP, Skountzou I, Albrecht RA et al. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 470(7335), 543-547 (2011
    • (2011) Nature , vol.470 , Issue.7335 , pp. 543-547
    • Kasturi, S.P.1    Skountzou, I.2    Albrecht, R.A.3
  • 20
    • 77951260924 scopus 로고    scopus 로고
    • The role of patternrecognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. The role of patternrecognition receptors in innate immunity: Update on Toll-like receptors. Nat. Immunol. 11(5), 373-384 (2010
    • (2010) Nat. Immunol , vol.11 , Issue.5 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 21
    • 77249147827 scopus 로고    scopus 로고
    • Vaccine adjuvants: A priority for vaccine research
    • Working Group convened by EUROPRISE
    • Harandi AM, Medaglini D, Shattock RJ; Working Group convened by EUROPRISE. Vaccine adjuvants: A priority for vaccine research. Vaccine 28(12), 2363-2366 (2010
    • (2010) Vaccine , vol.28 , Issue.12 , pp. 2363-2366
    • Harandi, A.M.1    Medaglini, D.2    Shattock, R.J.3
  • 22
    • 58049220365 scopus 로고    scopus 로고
    • Pattern recognition receptors and control of adaptive immunity
    • Palm NW, Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol. Rev. 227(1), 221-233 (2009
    • (2009) Immunol. Rev , vol.227 , Issue.1 , pp. 221-233
    • Palm, N.W.1    Medzhitov, R.2
  • 23
    • 33846194125 scopus 로고    scopus 로고
    • Innate immunity-cross-Talk with adaptive immunity through pattern recognition receptors and cytokines
    • Kabelitz D, Medzhitov R. Innate immunity-cross-Talk with adaptive immunity through pattern recognition receptors and cytokines. Curr. Opin. Immunol. 19(1), 1-3 (2007
    • (2007) Curr. Opin. Immunol , vol.19 , Issue.1 , pp. 1-3
    • Kabelitz, D.1    Medzhitov, R.2
  • 25
    • 32944455665 scopus 로고    scopus 로고
    • Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2 7 8 and 9 to stimulate polyvalent immunity
    • Querec T, Bennouna S, Alkan S et al Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J. Exp. Med. 203(2), 413-424 (2006
    • (2006) J Exp Med , vol.203 , Issue.2 , pp. 413-424
    • Querec, T.1    Bennouna, S.2    Alkan, S.3
  • 27
    • 0041349291 scopus 로고    scopus 로고
    • TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG
    • Heldwein KA, Liang MD, Andresen TK et al. TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG. J. Leukoc. Biol. 74(2), 277-286 (2003
    • (2003) J. Leukoc. Biol , vol.74 , Issue.2 , pp. 277-286
    • Heldwein, K.A.1    Liang, M.D.2    Andresen, T.K.3
  • 28
    • 84872267596 scopus 로고    scopus 로고
    • Bacillus Calmette-Guerin (BCG immunotherapy for bladder cancer: Current understanding and perspectives on engineered BCG vaccine
    • Kawai K, Miyazaki J, Joraku A, Nishiyama H, Akaza H. Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: Current understanding and perspectives on engineered BCG vaccine. Cancer Sci. 104(1), 22-27 (2013
    • (2013) Cancer Sci , vol.104 , Issue.1 , pp. 22-27
    • Kawai, K.1    Miyazaki, J.2    Joraku, A.3    Nishiyama, H.4    Akaza, H.5
  • 29
    • 84858381864 scopus 로고    scopus 로고
    • Modulating immunity as a therapy for bacterial infections
    • Hancock RE, Nijnik A, Philpott DJ. Modulating immunity as a therapy for bacterial infections. Nat. Rev. Microbiol. 10(4), 243-254 (2012
    • (2012) Nat. Rev. Microbiol , vol.10 , Issue.4 , pp. 243-254
    • Hancock, R.E.1    Nijnik, A.2    Philpott, D.J.3
  • 30
    • 0027507215 scopus 로고
    • Combined multidrug and Mycobacterium w vaccine therapy in patients with multibacillary leprosy
    • Zaheer SA, Mukherjee R, Ramkumar B et al. Combined multidrug and Mycobacterium w vaccine therapy in patients with multibacillary leprosy. J. Infect. Dis. 167(2), 401-410 (1993
    • (1993) J. Infect. Dis , vol.167 , Issue.2 , pp. 401-410
    • Zaheer, S.A.1    Mukherjee, R.2    Ramkumar, B.3
  • 31
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • Martinon F, Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26(8), 447-454 (2005
    • (2005) Trends Immunol , vol.26 , Issue.8 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 32
    • 66849089729 scopus 로고    scopus 로고
    • Unleashing the therapeutic potential of NOD-like receptors
    • Geddes K, Magalhad;es JG, Girardin SE. Unleashing the therapeutic potential of NOD-like receptors. Nat. Rev. Drug Discov. 8(6), 465-479 (2009
    • (2009) Nat. Rev. Drug Discov , vol.8 , Issue.6 , pp. 465-479
    • Geddes, K.1    Magalhad2    es, J.G.3    Girardin, S.E.4
  • 33
    • 84871037616 scopus 로고    scopus 로고
    • A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants
    • Agnandji ST, Lell B, Fernandes JF et al. A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N. Engl. J. Med 367(24), 2284-2295 (2012
    • (2012) N. Engl. J. Med , vol.367 , Issue.24 , pp. 2284-2295
    • Agnandji, S.T.1    Lell, B.2    Fernandes, J.F.3
  • 34
    • 84868094428 scopus 로고    scopus 로고
    • Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8? T-cell responses in melanoma patients
    • Goldinger SM, Dummer R, Baumgaertner P et al. Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8? T-cell responses in melanoma patients. Eur. J. Immunol. 42(11), 3049-3061 (2012
    • (2012) Eur. J. Immunol , vol.42 , Issue.11 , pp. 3049-3061
    • Goldinger, S.M.1    Dummer, R.2    Baumgaertner, P.3
  • 35
    • 84863084360 scopus 로고    scopus 로고
    • Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naive adults
    • Remarque EJ, Roestenberg M, Younis S et al. Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naive adults. PLoS ONE 7(6), e38898 (2012
    • (2012) PLoS ONE , vol.7 , Issue.6
    • Remarque, E.J.1    Roestenberg, M.2    Younis, S.3
  • 36
    • 84875818500 scopus 로고    scopus 로고
    • Improved CD4? T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial
    • M72 Study Group
    • Leroux-Roels I, Forgus S, De Boever F et al.; M72 Study Group. Improved CD4? T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial. Vaccine 31(17), 2196-2206 (2013
    • (2013) Vaccine , vol.31 , Issue.17 , pp. 2196-2206
    • Leroux-Roels, I.1    Forgus, S.2    De Boever, F.3
  • 37
    • 79951823624 scopus 로고    scopus 로고
    • An adjuvanted polyprotein HIV-1 vaccine induces polyfunctional cross-reactive CD4+ T cell responses in seronegative volunteers
    • Van Braeckel E, Bourguignon P, Koutsoukos M et al. An adjuvanted polyprotein HIV-1 vaccine induces polyfunctional cross-reactive CD4+ T cell responses in seronegative volunteers. Clin. Infect. Dis. 52(4), 522-531 (2011
    • (2011) Clin. Infect. Dis , vol.52 , Issue.4 , pp. 522-531
    • Van Braeckel, E.1    Bourguignon, P.2    Koutsoukos, M.3
  • 38
    • 39149121505 scopus 로고    scopus 로고
    • Recombinant gp350 vaccine for infectious mononucleosis: A phase 2, randomized, double-blind, placebo-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adults
    • Sokal EM, Hoppenbrouwers K, Vandermeulen C et al. Recombinant gp350 vaccine for infectious mononucleosis: A phase 2, randomized, double-blind, placebo-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adults. J. Infect. Dis. 196(12), 1749-1753 (2007
    • (2007) J. Infect. Dis , vol.196 , Issue.12 , pp. 1749-1753
    • Sokal, E.M.1    Hoppenbrouwers, K.2    Vandermeulen, C.3
  • 39
    • 59849116262 scopus 로고    scopus 로고
    • Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients
    • Fourcade J, Kudela P, Andrade Filho PA et al. Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients. J. Immunother. 31(8), 781-791 (2008
    • (2008) J. Immunother , vol.31 , Issue.8 , pp. 781-791
    • Fourcade, J.1    Kudela, P.2    Andrade Filho, P.A.3
  • 40
    • 74049118785 scopus 로고    scopus 로고
    • Tumor-reactive cd8+ t-cell responses after vaccination with ny-eso-1 peptide cpg 7909 and montanide isa-51: Association with survival
    • Karbach J, Gnjatic S, Bender A et al. Tumor-reactive CD8+ T-cell responses after vaccination with NY-ESO-1 peptide, CpG 7909 and Montanide ISA-51: Association with survival. Int. J. Cancer 126(4), 909-918 (2010
    • (2010) Int. J. Cancer , vol.126 , Issue.4 , pp. 909-918
    • Karbach, J.1    Gnjatic, S.2    Bender, A.3
  • 41
    • 84870359509 scopus 로고    scopus 로고
    • Phase I trial of overlapping long peptides from a tumor self-Antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients
    • Sabbatini P, Tsuji T, Ferran L et al. Phase I trial of overlapping long peptides from a tumor self-Antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients. Clin. Cancer Res. 18(23), 6497-6508 (2012
    • (2012) Clin. Cancer Res , vol.18 , Issue.23 , pp. 6497-6508
    • Sabbatini, P.1    Tsuji, T.2    Ferran, L.3
  • 42
    • 84872801225 scopus 로고    scopus 로고
    • Trial Watch: Experimental Toll-like receptor agonists for cancer therapy
    • Galluzzi L, Vacchelli E, Eggermont A et al. Trial Watch: Experimental Toll-like receptor agonists for cancer therapy. Oncoimmunology 1(5), 699-716 (2012
    • (2012) Oncoimmunology , vol.1 , Issue.5 , pp. 699-716
    • Galluzzi, L.1    Vacchelli, E.2    Eggermont, A.3
  • 43
    • 77957876452 scopus 로고    scopus 로고
    • Mycobacterium bovis bacillus Calmette-Gué;rin-induced macrophage cytotoxicity against bladder cancer cells
    • Luo Y, Knudson MJ. Mycobacterium bovis bacillus Calmette-Gué;rin- induced macrophage cytotoxicity against bladder cancer cells. Clin. Dev. Immunol. 2010, 357591 (2010
    • (2010) Clin. Dev. Immunol , vol.2010 , pp. 357591
    • Luo, Y.1    Knudson, M.J.2
  • 44
    • 84857067056 scopus 로고    scopus 로고
    • Role of bacillus Calmette-Gué;rin in the treatment of advanced melanoma
    • Stewart JH 4th, Levine EA. Role of bacillus Calmette-Gué;rin in the treatment of advanced melanoma. Expert Rev. Anticancer Ther. 11(11), 1671-1676 (2011
    • (2011) Expert Rev. Anticancer Ther , vol.11 , Issue.11 , pp. 1671-1676
    • Stewart IV, J.H.1    Levine, E.A.2
  • 45
    • 33646697743 scopus 로고    scopus 로고
    • Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates
    • Wille-Reece U, Flynn BJ, Loré; K et al. Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates. J. Exp. Med. 203(5), 1249-1258 (2006
    • (2006) J. Exp. Med , vol.203 , Issue.5 , pp. 1249-1258
    • Wille-Reece, U.1    Flynn, B.J.2    Loré3    , K.4
  • 46
    • 22144433725 scopus 로고    scopus 로고
    • Towards therapeutic vaccines for colorectal carcinoma: A review of clinical trials
    • Mosolits S, Nilsson B, Mellstedt H. Towards therapeutic vaccines for colorectal carcinoma: A review of clinical trials. Expert Rev. Vaccines 4(3), 329-350 (2005
    • (2005) Expert Rev. Vaccines , vol.4 , Issue.3 , pp. 329-350
    • Mosolits, S.1    Nilsson, B.2    Mellstedt, H.3
  • 47
    • 77950542752 scopus 로고    scopus 로고
    • Targeting Toll-like receptors: Emerging therapeutics?
    • Hennessy EJ, Parker AE, O'Neill LA. Targeting Toll-like receptors: Emerging therapeutics? Nat. Rev. Drug Discov. 9(4), 293-307 (2010
    • (2010) Nat Rev. Drug Discov , vol.9 , Issue.4 , pp. 293-307
    • Hennessy, E.J.1    Parker, A.E.2    O'Neill, L.A.3
  • 48
    • 84877262630 scopus 로고    scopus 로고
    • Trial Watch FDA -Approved Toll-like receptor agonists for cancer therapy
    • Vacchelli E, Galluzzi L, Eggermont A et al. Trial watch: FDA-Approved Toll-like receptor agonists for cancer therapy. Oncoimmunology 1(6), 894-907 (2012
    • (2012) Oncoimmunology , vol.1 , Issue.6 , pp. 894-907
    • Vacchelli, E.1    Galluzzi, L.2    Eggermont, A.3
  • 49
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86(6), 973-983 (1996
    • (1996) Cell , vol.86 , Issue.6 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 50
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388(6640), 394-397 (1997
    • (1997) Nature , vol.388 , Issue.6640 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 51
    • 51349158231 scopus 로고    scopus 로고
    • Signalling adaptors used by Toll-like receptors: An update
    • Kenny EF, O'Neill LA. Signalling adaptors used by Toll-like receptors: An update. Cytokine 43(3), 342-349 (2008
    • (2008) Cytokine , vol.43 , Issue.3 , pp. 342-349
    • Kenny, E.F.1    O'Neill, L.A.2
  • 52
    • 55849138791 scopus 로고    scopus 로고
    • Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines
    • Zhu Q, Egelston C, Vivekanandhan A et al. Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines. Proc. Natl Acad. Sci. USA 105(42), 16260-16265 (2008
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.42 , pp. 16260-16265
    • Zhu, Q.1    Egelston, C.2    Vivekanandhan, A.3
  • 53
    • 46749136412 scopus 로고    scopus 로고
    • When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction
    • O'Neill LA. When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction. Immunity 29(1), 12-20 (2008
    • (2008) Immunity , vol.29 , Issue.1 , pp. 12-20
    • O'Neill, L.A.1
  • 54
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6(8), 769-776 (2005
    • (2005) Nat. Immunol , vol.6 , Issue.8 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 55
    • 23644449245 scopus 로고    scopus 로고
    • The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3 4, and 7/8 results in synergistic cytokine production by dendritic cells
    • Roelofs MF, Joosten LA, Abdollahi-Roodsaz S et al. The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum. 52(8), 2313-2322 (2005
    • (2005) Arthritis Rheum , vol.52 , Issue.8 , pp. 2313-2322
    • Roelofs, M.F.1    Joosten, L.A.2    Abdollahi-Roodsaz, S.3
  • 56
    • 33847021499 scopus 로고    scopus 로고
    • Toll-like receptor (TLR 2-9 agonistsinduced cytokines and chemokines I. Comparison with T cell receptor-induced responses
    • Ghosh TK, Mickelson DJ, Fink J et al. Toll-like receptor (TLR) 2-9 agonistsinduced cytokines and chemokines: I. Comparison with T cell receptor-induced responses. Cell. Immunol. 243(1), 48-57 (2006
    • (2006) Cell. Immunol , vol.243 , Issue.1 , pp. 48-57
    • Ghosh, T.K.1    Mickelson, D.J.2    Fink, J.3
  • 57
    • 84870805509 scopus 로고    scopus 로고
    • Cortical functional connectivity under different auditory attentional efforts
    • Hong X, Tong S. Cortical functional connectivity under different auditory attentional efforts. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2012, 6196-6199 (2012
    • (2012) Conf. Proc IEEE Eng. Med. Biol. Soc , vol.2012 , pp. 6196-6199
    • Hong, X.1    Tong, S.2
  • 58
    • 84868216252 scopus 로고    scopus 로고
    • Combined TLR stimulation with Pam3Cys and Poly I: C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy
    • Lim SN, Kuhn S, Hyde E, Ronchese F. Combined TLR stimulation with Pam3Cys and Poly I: C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy. J. Immunother. 35(9), 670-679 (2012
    • (2012) J. Immunother , vol.35 , Issue.9 , pp. 670-679
    • Lim, S.N.1    Kuhn, S.2    Hyde, E.3    Ronchese, F.4
  • 59
    • 69349101739 scopus 로고    scopus 로고
    • Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-Targeted antigens by synergistic toll-like receptor ligands
    • Grossmann C, Tenbusch M, Nchinda G et al. Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-Targeted antigens by synergistic toll-like receptor ligands. BMC Immunol. 10, 43 (2009
    • (2009) BMC Immunol , vol.10 , pp. 43
    • Grossmann, C.1    Tenbusch, M.2    Nchinda, G.3
  • 60
    • 76649093262 scopus 로고    scopus 로고
    • Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice
    • Zhu Q, Egelston C, Gagnon S et al. Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. J. Clin. Invest. 120(2), 607-616 (2010
    • (2010) J. Clin. Invest , vol.120 , Issue.2 , pp. 607-616
    • Zhu, Q.1    Egelston, C.2    Gagnon, S.3
  • 61
    • 4143131229 scopus 로고    scopus 로고
    • Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity
    • Whitmore MM, DeVeer MJ, Edling A et al. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res. 64(16), 5850-5860 (2004
    • (2004) Cancer Res , vol.64 , Issue.16 , pp. 5850-5860
    • Whitmore, M.M.1    DeVeer, M.J.2    Edling, A.3
  • 62
    • 79960800986 scopus 로고    scopus 로고
    • Targeting TLRs expands the antibody repertoire in response to a malaria vaccine
    • 93ra69
    • Wiley SR, Raman VS, Desbien A et al. Targeting TLRs expands the antibody repertoire in response to a malaria vaccine. Sci. Transl. Med. 3(93), 93ra69 (2011
    • (2011) Sci. Transl. Med , vol.3 , Issue.93
    • Wiley, S.R.1    Raman, V.S.2    Desbien, A.3
  • 63
    • 77954945284 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation
    • Garin A, Meyer-Hermann M, Contie M et al. Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity 33(1), 84-95 (2010
    • (2010) Immunity , vol.33 , Issue.1 , pp. 84-95
    • Garin, A.1    Meyer-Hermann, M.2    Contie, M.3
  • 64
    • 77956585400 scopus 로고    scopus 로고
    • Intranasal administration of adjuvantcombined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus
    • Ichinohe T, Ainai A, Ami Y et al. Intranasal administration of adjuvantcombined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus. J. Med. Virol. 82(10), 1754-1761 (2010
    • (2010) J. Med. Virol , vol.82 , Issue.10 , pp. 1754-1761
    • Ichinohe, T.1    Ainai, A.2    Ami, Y.3
  • 65
    • 75449106817 scopus 로고    scopus 로고
    • Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine
    • Ainai A, Ichinohe T, Tamura S et al. Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine. J. Med. Virol. 82(3), 476-484 (2010
    • (2010) J. Med. Virol , vol.82 , Issue.3 , pp. 476-484
    • Ainai, A.1    Ichinohe, T.2    Tamura, S.3
  • 66
    • 78650576197 scopus 로고    scopus 로고
    • Use of defined TLR ligands as adjuvants within human vaccines
    • Duthie MS, Windish HP, Fox CB, Reed SG. Use of defined TLR ligands as adjuvants within human vaccines. Immunol. Rev. 239(1), 178-196 (2011
    • (2011) Immunol. Rev , vol.239 , Issue.1 , pp. 178-196
    • Duthie, M.S.1    Windish, H.P.2    Fox, C.B.3    Reed, S.G.4
  • 67
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453(7198), 1122-1126 (2008
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 68
    • 77749285681 scopus 로고    scopus 로고
    • The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants
    • Harris J, Sharp FA, Lavelle EC. The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants. Eur. J. Immunol. 40(3), 634-638 (2010
    • (2010) Eur. J. Immunol , vol.40 , Issue.3 , pp. 634-638
    • Harris, J.1    Sharp, F.A.2    Lavelle, E.C.3
  • 69
    • 34247254780 scopus 로고    scopus 로고
    • Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity
    • Fritz JH, Le Bourhis L, Sellge G et al. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity 26(4), 445-459 (2007
    • (2007) Immunity , vol.26 , Issue.4 , pp. 445-459
    • Fritz, J.H.1    Le Bourhis, L.2    Sellge, G.3
  • 70
    • 33646914384 scopus 로고    scopus 로고
    • MDP and other muropeptides -direct and synergistic effects on the immune system
    • Traub S, von Aulock S, Hartung T, Hermann C. MDP and other muropeptides -direct and synergistic effects on the immune system. J. Endotoxin Res. 12(2), 69-85 (2006
    • (2006) J. Endotoxin Res , vol.12 , Issue.2 , pp. 69-85
    • Traub, S.1    Von Aulock, S.2    Hartung, T.3    Hermann, C.4
  • 71
    • 84875233002 scopus 로고    scopus 로고
    • TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2
    • Schwarz H, Posselt G, Wurm P, Ulbing M, Duschl A, Horejs-Hoeck J TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2. Immunobiology 218(4), 533-542 (2013
    • (2013) Immunobiology , vol.218 , Issue.4 , pp. 533-542
    • Schwarz, H.1    Posselt, G.2    Wurm, P.3    Ulbing, M.4    Duschl, A.5    Horejs-Hoeck, J.6
  • 72
    • 28444471235 scopus 로고    scopus 로고
    • Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
    • Tada H, Aiba S, Shibata K, Ohteki T, Takada H. Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect. Immun. 73(12), 7967-7976 (2005
    • (2005) Infect. Immun , vol.73 , Issue.12 , pp. 7967-7976
    • Tada, H.1    Aiba, S.2    Shibata, K.3    Ohteki, T.4    Takada, H.5
  • 73
    • 12444259829 scopus 로고    scopus 로고
    • Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2-And NOD1-dependent manner, respectively, in human monocytic cells in culture
    • Uehara A, Yang S, Fujimoto Y et al. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2-And NOD1-dependent manner, respectively, in human monocytic cells in culture. Cell. Microbiol. 7(1), 53-61 (2005
    • (2005) Cell. Microbiol , vol.7 , Issue.1 , pp. 53-61
    • Uehara, A.1    Yang, S.2    Fujimoto, Y.3
  • 74
    • 49749105995 scopus 로고    scopus 로고
    • An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results
    • Schiller JT, Castellsagué; X, Villa LL, Hildesheim A. An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results. Vaccine 26(Suppl. 10), K53-K61 (2008
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 10
    • Schiller, J.T.1    Castellsagué2    , X.3    Villa, L.L.4    Hildesheim, A.5
  • 75
    • 33746096523 scopus 로고    scopus 로고
    • Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/ aluminium salt combination (AS04) compared to aluminium salt only
    • Giannini SL, Hanon E, Moris P et al. Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/ aluminium salt combination (AS04) compared to aluminium salt only. Vaccine 24(33-34), 5937-5949 (2006
    • (2006) Vaccine , vol.24 , Issue.33-34 , pp. 5937-5949
    • Giannini, S.L.1    Hanon, E.2    Moris, P.3
  • 76
    • 34250850161 scopus 로고    scopus 로고
    • Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: An interim analysis of a Phase III double-blind, randomised controlled trial
    • HPV PATRICIA study group
    • Paavonen J, Jenkins D, Bosch FX et al.; HPV PATRICIA study group. Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: An interim analysis of a Phase III double-blind, randomised controlled trial. Lancet 369(9580), 2161-2170 (2007
    • (2007) Lancet , vol.369 , Issue.9580 , pp. 2161-2170
    • Paavonen, J.1    Jenkins, D.2    Bosch, F.X.3
  • 77
    • 34249047002 scopus 로고    scopus 로고
    • Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: A combined analysis of three randomised clinical trials
    • Joura EA, Leodolter S, Hernandez-Avila M et al. Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: A combined analysis of three randomised clinical trials. Lancet 369(9574), 1693-1702 (2007
    • (2007) Lancet , vol.369 , Issue.9574 , pp. 1693-1702
    • Joura, E.A.1    Leodolter, S.2    Hernandez-Avila, M.3
  • 78
    • 33845273878 scopus 로고    scopus 로고
    • High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up
    • Villa LL, Costa RL, Petta CA et al. High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up. Br. J. Cancer 95(11), 1459-1466 (2006
    • (2006) Br J. Cancer , vol.95 , Issue.11 , pp. 1459-1466
    • Villa, L.L.1    Costa, R.L.2    Petta, C.A.3
  • 79
    • 84861682707 scopus 로고    scopus 로고
    • Comparison of the immune responses to the CIA06-Adjuvanted human papillomavirus L1 VLP vaccine with those against the licensed HPV vaccine Cervarix™ in mice
    • Han JE, Wui SR, Park SA et al. Comparison of the immune responses to the CIA06-Adjuvanted human papillomavirus L1 VLP vaccine with those against the licensed HPV vaccine Cervarix™ in mice. Vaccine 30(28), 4127-4134 (2012
    • (2012) Vaccine , vol.30 , Issue.28 , pp. 4127-4134
    • Han, J.E.1    Wui, S.R.2    Park, S.A.3
  • 80
    • 29144444035 scopus 로고    scopus 로고
    • Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-Analysis of longitudinal studies
    • Freeman EE, Weiss HA, Glynn JR, Cross PL, Whitworth JA, Hayes RJ. Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-Analysis of longitudinal studies. AIDS 20(1), 73-83 (2006
    • (2006) AIDS , vol.20 , Issue.1 , pp. 73-83
    • Freeman, E.E.1    Weiss, H.A.2    Glynn, J.R.3    Cross, P.L.4    Whitworth, J.A.5    Hayes, R.J.6
  • 81
    • 84867023587 scopus 로고    scopus 로고
    • Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge
    • Morello CS, Kraynyak KA, Levinson MS, Chen Z, Lee KF, Spector DH. Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge. Vaccine 30(46), 6541-6550 (2012
    • (2012) Vaccine , vol.30 , Issue.46 , pp. 6541-6550
    • Morello, C.S.1    Kraynyak, K.A.2    Levinson, M.S.3    Chen, Z.4    Lee, K.F.5    Spector, D.H.6
  • 82
    • 42549161952 scopus 로고    scopus 로고
    • Varicella vaccine in the United States: A decade of prevention and the way forward
    • Gershon AA, Arvin AM, Levin MJ, Seward JF, Schmid DS. Varicella vaccine in the United States: A decade of prevention and the way forward. J. Infect. Dis. 197(Suppl. 2), S39-S40 (2008
    • (2008) J. Infect. Dis , vol.197 , Issue.SUPPL. 2
    • Gershon, A.A.1    Arvin, A.M.2    Levin, M.J.3    Seward, J.F.4    Schmid, D.S.5
  • 83
    • 84859427365 scopus 로고    scopus 로고
    • Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice
    • Dendouga N, Fochesato M, Lockman L, Mossman S, Giannini SL. Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice. Vaccine 30(20), 3126-3135 (2012
    • (2012) Vaccine , vol.30 , Issue.20 , pp. 3126-3135
    • Dendouga, N.1    Fochesato, M.2    Lockman, L.3    Mossman, S.4    Giannini, S.L.5
  • 84
    • 80051906989 scopus 로고    scopus 로고
    • A combination of the TLR4 agonist CIA05 and alum promotes the immune responses to Bacillus anthracis protective antigen in mice
    • Wui SR, Kim HK, Han JE et al. A combination of the TLR4 agonist CIA05 and alum promotes the immune responses to Bacillus anthracis protective antigen in mice. Int. Immunopharmacol. 11(9), 1195-1204 (2011
    • (2011) Int. Immunopharmacol , vol.11 , Issue.9 , pp. 1195-1204
    • Wui, S.R.1    Kim, H.K.2    Han, J.E.3
  • 86
    • 33645222064 scopus 로고    scopus 로고
    • Task force on biological and chemical agent threats, public health directorate european commission, luxembourg bichat guidelines for the clinical manage-ment of anthrax and bioterrorism-related anthrax
    • Bossi P, Tegnell A, Baka A et al.; Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg. Bichat guidelines for the clinical manage-ment of anthrax and bioterrorism-related anthrax. Euro Surveill. 9(12), E3-E4 (2004
    • (2004) Euro Surveill , vol.9 , Issue.12
    • Bossi, P.1    Tegnell, A.2    Baka, A.3
  • 87
    • 33845195783 scopus 로고    scopus 로고
    • Increased potency of BioThrax anthrax vaccine with the addition of the C-class CpG oligonucleotide adjuvant CPG 10109
    • Gu M, Hine PM, James Jackson W, Giri L, Nabors GS Increased potency of BioThrax anthrax vaccine with the addition of the C-class CpG oligonucleotide adjuvant CPG 10109. Vaccine 25(3), 526-534 (2007
    • (2007) Vaccine , vol.25 , Issue.3 , pp. 526-534
    • Gu, M.1    Hine, P.M.2    James Jackson, W.3    Giri, L.4    Nabors, G.S.5
  • 88
    • 54049105664 scopus 로고    scopus 로고
    • Effect of CpG oligonucleotides on vaccine-induced B cell memory
    • Tross D, Klinman DM. Effect of CpG oligonucleotides on vaccine-induced B cell memory. J. Immunol. 181(8), 5785-5790 (2008
    • (2008) J. Immunol , vol.181 , Issue.8 , pp. 5785-5790
    • Tross, D.1    Klinman, D.M.2
  • 89
    • 80051574871 scopus 로고    scopus 로고
    • Marked enhancement of the immune response to biothrax® anthrax vaccine adsorbed) by the tlr9 agonist cpg 7909 in healthy volunteers
    • Rynkiewicz D, Rathkopf M, Sim I et al. Marked enhancement of the immune response to BioThrax® (Anthrax Vaccine Adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers. Vaccine 29(37), 6313-6320 (2011
    • (2011) Vaccine , vol.29 , Issue.37 , pp. 6313-6320
    • Rynkiewicz, D.1    Rathkopf, M.2    Sim, I.3
  • 90
    • 84861985242 scopus 로고    scopus 로고
    • MF59 formulated with CpG ODN as a potent adjuvant of recombinant HSP65-MUC1 for inducing anti-MUC1+ tumor immunity in mice
    • Yang M, Yan Y, Fang M et al. MF59 formulated with CpG ODN as a potent adjuvant of recombinant HSP65-MUC1 for inducing anti-MUC1+ tumor immunity in mice. Int. Immunopharmacol. 13(4), 408-416 (2012
    • (2012) Int. Immunopharmacol , vol.13 , Issue.4 , pp. 408-416
    • Yang, M.1    Yan, Y.2    Fang, M.3
  • 91
    • 84870516100 scopus 로고    scopus 로고
    • Insect cell-expressed hemagglutinin with CpG oligodeoxynucleotides plus alum as an adjuvant is a potential pandemic influenza vaccine candidate
    • Gong M, Zhou J, Yang C et al. Insect cell-expressed hemagglutinin with CpG oligodeoxynucleotides plus alum as an adjuvant is a potential pandemic influenza vaccine candidate. Vaccine 30(52), 7498-7505 (2012
    • (2012) Vaccine , vol.30 , Issue.52 , pp. 7498-7505
    • Gong, M.1    Zhou, J.2    Yang, C.3
  • 92
    • 9644259300 scopus 로고    scopus 로고
    • Human cytomegalovirus: Clinical aspects, immune regulation and emerging treatments
    • Ghandi MK, Khanna R. Human cytomegalovirus: Clinical aspects, immune regulation and emerging treatments. Lancet Infect. Dis. 4(12), 725-738 (2004
    • (2004) Lancet Infect. Dis , vol.4 , Issue.12 , pp. 725-738
    • Ghandi, M.K.1    Khanna, R.2
  • 93
    • 59649121998 scopus 로고    scopus 로고
    • Immunobiology of human cytomegalovirus: From bench to bedside
    • Crough T, Khanna R. Immunobiology of human cytomegalovirus: From bench to bedside. Clin. Microb. Rev. 22(1), 76-98 (2009
    • (2009) Clin. Microb. Rev , vol.22 , Issue.1 , pp. 76-98
    • Crough, T.1    Khanna, R.2
  • 94
    • 79955578459 scopus 로고    scopus 로고
    • Recombinant glycoprotein B vaccine formulation with Toll-like receptor 9 agonist and immunestimulating complex induces specific immunity against multiple strains of cytomegalovirus
    • Dasari V, Smith C, Zhong J, Scott G, Rawlinson W, Khanna R. Recombinant glycoprotein B vaccine formulation with Toll-like receptor 9 agonist and immunestimulating complex induces specific immunity against multiple strains of cytomegalovirus. J. Gen. Virol. 92(Pt 5), 1021-1031 (2011
    • (2011) J. Gen. Virol , vol.92 , Issue.PART 5 , pp. 1021-1031
    • Dasari, V.1    Smith, C.2    Zhong, J.3    Scott, G.4    Rawlinson, W.5    Khanna, R.6
  • 95
    • 79953216363 scopus 로고    scopus 로고
    • Hepatitis C virus soluble E2 in combination with QuilA and CpG ODN induces neutralizing antibodies in mice
    • Naarding MA, Falkowska E, Xiao H, Dragic T. Hepatitis C virus soluble E2 in combination with QuilA and CpG ODN induces neutralizing antibodies in mice. Vaccine 29(16), 2910-2917 (2011
    • (2011) Vaccine , vol.29 , Issue.16 , pp. 2910-2917
    • Naarding, M.A.1    Falkowska, E.2    Xiao, H.3    Dragic, T.4
  • 96
    • 80355131482 scopus 로고    scopus 로고
    • Enhancement of humoral immunity in mice by coupling pUCpGs10 and aluminium to the HCV recombinant immunogen
    • Zhan N, Xiu BS, Wang GH et al. Enhancement of humoral immunity in mice by coupling pUCpGs10 and aluminium to the HCV recombinant immunogen. Virol. J. 8, 507 (2011
    • (2011) Virol. J. , vol.8 , pp. 507
    • Zhan, N.1    Xiu, B.S.2    Wang, G.H.3
  • 97
    • 0242608403 scopus 로고    scopus 로고
    • Protective immunity of pneumococcal glycoconjugates
    • Lee CJ, Lee LH, Frasch CE. Protective immunity of pneumococcal glycoconjugates. Crit. Rev. Microbiol. 29(4), 333-349 (2003
    • (2003) Crit. Rev. Microbiol , vol.29 , Issue.4 , pp. 333-349
    • Lee, C.J.1    Lee, L.H.2    Frasch, C.E.3
  • 98
    • 79960342392 scopus 로고    scopus 로고
    • A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae
    • Denoël P, Philipp MT, Doyle L, Martin D, Carletti G, Poolman JT. A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae. Vaccine 29(33), 5495-5501 (2011
    • (2011) Vaccine , vol.29 , Issue.33 , pp. 5495-5501
    • Denoël, P.1    Philipp, M.T.2    Doyle, L.3    Martin, D.4    Carletti, G.5    Poolman, J.T.6
  • 99
    • 33646365866 scopus 로고    scopus 로고
    • Experimental infection of rhesus macaques with Streptococcus pneumoniae: A possible model for vaccine assessment
    • Philipp MT, Purcell JE, Martin DS et al. Experimental infection of rhesus macaques with Streptococcus pneumoniae: A possible model for vaccine assessment. J. Med. Primatol. 35(3), 113-122 (2006
    • (2006) J. Med. Primatol , vol.35 , Issue.3 , pp. 113-122
    • Philipp, M.T.1    Purcell, J.E.2    Martin, D.S.3
  • 100
    • 78650530937 scopus 로고    scopus 로고
    • Codelivery of adjuvants at the primary immunization site is essential for evoking a robust immune response to neoglycoconjugates
    • Safari D, Dekker HA, Rijkers G, Snippe H. Codelivery of adjuvants at the primary immunization site is essential for evoking a robust immune response to neoglycoconjugates. Vaccine 29(4), 849-854 (2011
    • (2011) Vaccine , vol.29 , Issue.4 , pp. 849-854
    • Safari, D.1    Dekker, H.A.2    Rijkers, G.3    Snippe, H.4
  • 101
    • 35348997373 scopus 로고    scopus 로고
    • ISCOMATRIXTM adjuvant for prophylactic and therapeutic vaccines
    • Drane D, Boyle J, Maraskovsky E. ISCOMATRIXTM adjuvant for prophylactic and therapeutic vaccines. Expert Review of Vaccines 6(5), 761-772 (2005
    • (2005) Expert Review of Vaccines , vol.6 , Issue.5 , pp. 761-772
    • Drane, D.1    Boyle, J.2    Maraskovsky, E.3
  • 102
    • 79960413988 scopus 로고    scopus 로고
    • ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells
    • Duewell P, Kisser U, Heckelsmiller K et al. ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells. J. Immunol. 187(1), 55-63 (2011
    • (2011) J. Immunol , vol.187 , Issue.1 , pp. 55-63
    • Duewell, P.1    Kisser, U.2    Heckelsmiller, K.3
  • 103
    • 84861661926 scopus 로고    scopus 로고
    • ISCOMATRIX vaccines mediate CD8+T-cell cross-priming by a MyD88-dependent signaling pathway
    • Wilson NS, Yang B, Morelli AB et al. ISCOMATRIX vaccines mediate CD8+T-cell cross-priming by a MyD88-dependent signaling pathway. Immunol. Cell Biol. 90(5), 540-552 (2012
    • (2012) Immunol. Cell Biol , vol.90 , Issue.5 , pp. 540-552
    • Wilson, N.S.1    Yang, B.2    Morelli, A.B.3
  • 104
    • 77953647540 scopus 로고    scopus 로고
    • ISCOMATRIX® vaccines: Safety in human clinical studies
    • Mckenzie A, Gittleson C. ISCOMATRIX® vaccines: Safety in human clinical studies. Human Vaccines 6(3), 237-246 (2010
    • (2010) Human Vaccines , vol.6 , Issue.3 , pp. 237-246
    • Mckenzie, A.1    Gittleson, C.2
  • 105
    • 78650601347 scopus 로고    scopus 로고
    • An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma
    • Jacobs C, Duewell P, Heckelsmiller K et al. An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma. Int. J. Cancer 128(4), 897-907 (2011
    • (2011) Int. J. Cancer , vol.128 , Issue.4 , pp. 897-907
    • Jacobs, C.1    Duewell, P.2    Heckelsmiller, K.3
  • 106
    • 67650901824 scopus 로고    scopus 로고
    • Evaluation of vaccines for H5N1 influenza virus in ferrets reveals the potential for protective single-shot immunization
    • Middleton D, Rockman S, Pearse M et al. Evaluation of vaccines for H5N1 influenza virus in ferrets reveals the potential for protective single-shot immunization. J. Virol. 83(15), 7770-7778 (2009
    • (2009) J. Virol , vol.83 , Issue.15 , pp. 7770-7778
    • Middleton, D.1    Rockman, S.2    Pearse, M.3
  • 107
    • 77956894324 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9
    • Simmons DP, Canaday DH, Liu Y et al. Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9. J. Immunol. 185(4), 2405-2415 (2010
    • (2010) J Immunol , vol.185 , Issue.4 , pp. 2405-2415
    • Simmons, D.P.1    Canaday, D.H.2    Liu, Y.3
  • 108
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat. Immunol. 5(8), 800-808 (2004
    • (2004) Nat. Immunol , vol.5 , Issue.8 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3    Strober, W.4
  • 109
    • 0036679732 scopus 로고    scopus 로고
    • Of mice and men: Species variations of Toll-like receptor expression
    • Rehli M. Of mice and men: Species variations of Toll-like receptor expression. Trends Immunol. 23(8), 375-378 (2002
    • (2002) Trends Immunol , vol.23 , Issue.8 , pp. 375-378
    • Rehli, M.1
  • 110
    • 70349777300 scopus 로고    scopus 로고
    • Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
    • Belderbos ME, van Bleek GM, Levy O et al. Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life. Clin. Immunol. 133(2), 228-237 (2009
    • (2009) Clin. Immunol , vol.133 , Issue.2 , pp. 228-237
    • Belderbos, M.E.1    Van Bleek, G.M.2    Levy, O.3
  • 111
    • 77956397972 scopus 로고    scopus 로고
    • Acquisition of adult-like TLR4 and TLR9 responses during the first year of life
    • Nguyen M, Leuridan E, Zhang T et al. Acquisition of adult-like TLR4 and TLR9 responses during the first year of life. PLoS ONE 5(4), e10407 (2010
    • (2010) PLoS ONE , vol.5 , Issue.4
    • Nguyen, M.1    Leuridan, E.2    Zhang, T.3
  • 112
    • 33846208784 scopus 로고    scopus 로고
    • Age-Associated defect in human TLR-1/2 function
    • van Duin D, Mohanty S, Thomas V et al. Age-Associated defect in human TLR-1/2 function. J. Immunol. 178(2), 970-975 (2007
    • (2007) J. Immunol , vol.178 , Issue.2 , pp. 970-975
    • Van Duin, D.1    Mohanty, S.2    Thomas, V.3
  • 114
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12(4), 252-264 (2012
    • (2012) Nat. Rev. Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.