Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine

Journal of Medical Virology

Volumn 82, Issue 3, 2010, Pages 476-484

  Ainai, Akira ^a   Ichinohe, Takeshi ^a,b   Tamura, Shin Ichi ^a   Kurata, Takeshi ^a   Sata, Tetsutaro ^a   Tashiro, Masato ^a   Hasegawa, Hideki ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Influenza virus; Intranasal vaccine; Mucosal adjuvant; Poly(I:C); Zymosan

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INTERLEUKIN 10; INTERLEUKIN 6; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; BAGG ALBINO MOUSE; CELL ACTIVITY; CELL CULTURE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG EFFICACY; DRUG POTENTIATION; FUNGAL CELL; HUMORAL IMMUNITY; INFLUENZA; INFLUENZA VIRUS; MOUSE; NONHUMAN; SACCHAROMYCES CEREVISIAE;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, CD40; ANTIGENS, CD86; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; INFLUENZA VACCINES; MICE; MICE, INBRED BALB C; POLY I-C; SURVIVAL ANALYSIS; UP-REGULATION; VACCINES, INACTIVATED; ZYMOSAN;

MUS; ORTHOMYXOVIRIDAE; SACCHAROMYCES CEREVISIAE;

EID: 75449106817     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21694     Document Type: Article

References (35)

1. Asahi Y, Yoshikawa T, Watanabe I, Iwasaki T, Hasegawa H, Sato Y, Shimada S, NannoM, Matsuoka Y, Ohwaki M, Iwakura Y, Suzuki Y, Aizawa C, Sata T, Kurata T, Tamura S. 2002. Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines. J Immunol 168:2930-2938.
2. Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C, Hellman J. 2007. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J Immunol 178:1164-1171.
3. Blander JM, Medzhitov R. 2006. On regulation of phagosome maturation and antigen presentation. Nat Immunol 7:1029-1035.
4. Brown GD. 2006. Dectin-1: A signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 6:33-43.
5. Couch RB, Kasel JA. 1983. Immunity to influenza in man. Annu Rev Microbiol 37:529-549.
6. Davenport FM, Hennessy AV, Brandon FM, Webster RG, Barrett CD, Jr., Lease GO. 1964. Comparisons of serologic and febrile responses in humans to vaccination with influenza a viruses or their hemagglutinins. J Lab Clin Med 63:5-13.
7. Di Carlo FJ, Fiore JV. 1958. On the composition of zymosan. Science 127:756-757.
8. Gantner BN, SimmonsRM, Canavera SJ,Akira S, UnderhillDM.2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 197:1107-1117.
9. Gross O, Gewies A, Finger K, Schafer M, Sparwasser T, Peschel C, Forster I, Ruland J. 2006. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442:651-656.
10. Hasegawa H, Ichinohe T, Strong P, Watanabe I, Ito S, Tamura S, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T. 2005. Protection against influenza virus infection by intranasal administration of hemagglutinin vaccine with chitin microparticles as an adjuvant. J Med Virol 75:130-136.
11. Herre J,Marshall AS, Caron E, Edwards AD, Williams DL, Schweighoffer E, Tybulewicz V, Reis e Sousa C, Gordon S, Brown GD. 2004. Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood 104:4038-4045.
12. Ichinohe T, Watanabe I, Ito S, Fujii H, Moriyama M, Tamura S, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T, Hasegawa H. 2005. Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection. J Virol 79:2910-2919.
13. Ichinohe T, Watanabe I, Tao E, Ito S, Kawaguchi A, Tamura S, Takahashi H, Sawa H,Moriyama M, Chiba J, Komase K, Suzuki Y, Kurata T, Sata T, Hasegawa H. 2006. Protection against influenza virus infection by intranasal vaccine with surf clam microparticles (SMP) as an adjuvant. J Med Virol 78:954-963.
14. IwasakiA,Medzhitov R. 2004. Toll-like receptor control of the adaptive immune responses. Nat Immunol 5:987-995.
15. Kamijuku H, Nagata Y, Jiang X, Ichinohe T, Tashiro T, Mori K, TaniguchiM, HaseK, Ohno H, Shimaoka T, Yonehara S, Odagiri T, Tashiro M, SataT,Hasegawa H, SeinoKI. 2008.Mechanism ofNKT cell activation by intranasal coadministration of alpha-galactosylceramide, which can induce cross-protection against influenza viruses. Mucosal Immunol 1:208-218.
16. Kawai T, Akira S. 2006. Innate immune recognition of viral infection. Nat Immunol 7:131-137.
17. Lamb RA, Krug RM. 2001. Orthomyxoviridae: The viruses and their replication. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin A M, Roizman B, Straus SE, editors. Fields virology. 4th edition. Philadelphia: LippincottWilliams&Wilkins. pp. 1487-1531.
18. Liew FY, Russell SM, Appleyard G, Brand CM, Beale J. 1984. Crossprotection in mice infected with influenza Avirus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity. Eur J Immunol 14:350-356.
19. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, Schuler G. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223:77-92.
20. Murphy BR, Clements ML. 1989. The systemic and mucosal immune response of humans to influenza A virus. Curr Top Microbiol Immunol 146:107-116.
21. O'Neill LA. 2008. When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction. Immunity 29:12-20.
22. Robinson MJ, Sancho D, Slack EC, LeibundGut-Landmann S, Reis e Sousa C. 2006. Myeloid C-type lectins in innate immunity. Nat Immunol 7:1258-1265.
23. Rogers NC, Slack EC, Edwards AD, Nolte MA, SchulzO, Schweighoffer E, Williams DL, Gordon S, Tybulewicz VL, Brown GD, Reis e Sousa C. 2005. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22:507-517.
24. Saijo S, Fujikado N, Furuta T, Chung SH, Kotaki H, Seki K, Sudo K, Akira S, Adachi Y, Ohno N, Kinjo T, Nakamura K, Kawakami K, Iwakura Y. 2007. Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat Immunol 8:39-46.
25. Sever JL. 1962. Application of a microtechnique to viral serological investigations. J Immunol 88:320-329.
26. Slack EC, Robinson MJ, Hernanz-Falcon P, Brown GD, Williams DL, Schweighoffer E, Tybulewicz VL, Reis e Sousa C. 2007. Sykdependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan. Eur J Immunol 37:1600-1612.
27. Takeda K, Akira S. 2005. Toll-like receptors in innate immunity. Int Immunol 17:1-14.
28. Tamura S, Ito Y, Asanuma H, Hirabayashi Y, Suzuki Y, Nagamine T, Aizawa C, Kurata T. 1992a. Cross-protection against influenza virus infection afforded by trivalent inactivated vaccines inoculated intranasally with cholera toxin B subunit. J Immunol 149:981-988.
29. Tamura SI, Asanuma H, Ito Y, Hirabayashi Y, Suzuki Y, Nagamine T, Aizawa C, Kurata T, Oya A. 1992b. Superior cross-protective effect of nasal vaccination to subcutaneous inoculation with influenza hemagglutinin vaccine. Eur J Immunol 22:477-481.
30. Tamura S, Yamanaka A, Shimohara M, Tomita T, Komase K, Tsuda Y, Suzuki Y, Nagamine T, Kawahara K, DanbaraH, Aizawa C, Oya A, Kurata T. 1994. Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine. Vaccine 12:419-426.
31. Taylor PR, Tsoni SV, Willment JA, Dennehy KM, Rosas M, Findon H, HaynesK,Steele C, Botto M, Gordon S, Brown GD. 2007. Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol 8:31-38.
32. Tobita K, Sugiura A, Enomote C, Furuyama M. 1975. Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin. Med Microbiol Immunol 162:9-14.
33. Underdown BJ, Schiff JM. 1986. Immunoglobulin A: Strategic defense initiative at the mucosal surface. Annu Rev Immunol 4:389-417.
34. Wright PF, Webster RG. 2001. Orthomyxoviruses. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin AM, Roizman B, Straus SE, editors. Fields virology. 4th edition. Philadelphia: Lippincott Williams & Wilkins. pp. 1533-1579.
35. Yetter RA, Lehrer S, Ramphal R, Small PA, Jr. 1980. Outcome of influenza infection: Effect of site of initial infection and heterotypic immunity. Infect Immun 29:654-662.