-
1
-
-
34848837386
-
Taking dendritic cells into medicine
-
10.1038/nature06175 17898760
-
Steinman RM Banchereau J Taking dendritic cells into medicine Nature 2007, 449:419-426. 10.1038/nature06175 17898760
-
(2007)
Nature
, vol.449
, pp. 419-426
-
-
Steinman, R.M.1
Banchereau, J.2
-
2
-
-
0035903326
-
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
-
10.1084/jem.194.6.769 2195961 11560993
-
Hawiger D Inaba K Dorsett Y Guo M Mahnke K Rivera M Ravetch JV Steinman RM Nussenzweig MC Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo J Exp Med 2001, 194:769-779. 10.1084/jem.194.6.769 2195961 11560993
-
(2001)
J Exp Med
, vol.194
, pp. 769-779
-
-
Hawiger, D.1
Inaba, K.2
Dorsett, Y.3
Guo, M.4
Mahnke, K.5
Rivera, M.6
Ravetch, J.V.7
Steinman, R.M.8
Nussenzweig, M.C.9
-
3
-
-
0037122011
-
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
-
10.1084/jem.20021598 2196060 12486105
-
Bonifaz L Bonnyay D Mahnke K Rivera M Nussenzweig MC Steinman RM Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance J Exp Med 2002, 196:1627-1638. 10.1084/jem.20021598 2196060 12486105
-
(2002)
J Exp Med
, vol.196
, pp. 1627-1638
-
-
Bonifaz, L.1
Bonnyay, D.2
Mahnke, K.3
Rivera, M.4
Nussenzweig, M.C.5
Steinman, R.M.6
-
4
-
-
0034735552
-
The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
-
10.1083/jcb.151.3.673 2185598 11062267
-
Mahnke K Guo M Lee S Sepulveda H Swain SL Nussenzweig M Steinman RM The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments J Cell Biol 2000, 151:673-684. 10.1083/jcb.151.3.673 2185598 11062267
-
(2000)
J Cell Biol
, vol.151
, pp. 673-684
-
-
Mahnke, K.1
Guo, M.2
Lee, S.3
Sepulveda, H.4
Swain, S.L.5
Nussenzweig, M.6
Steinman, R.M.7
-
5
-
-
0038792101
-
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells
-
10.1182/blood-2002-10-3229 12543858
-
Mahnke K Qian Y Knop J Enk AH Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells Blood 2003, 101:4862-4869. 10.1182/blood-2002-10-3229 12543858
-
(2003)
Blood
, vol.101
, pp. 4862-4869
-
-
Mahnke, K.1
Qian, Y.2
Knop, J.3
Enk, A.H.4
-
7
-
-
2942523789
-
Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
-
10.1016/j.immuni.2004.05.002 15189735
-
Hawiger D Masilamani RF Bettelli E Kuchroo VK Nussenzweig MC Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo Immunity 2004, 20:695-705. 10.1016/j.immuni.2004.05.002 15189735
-
(2004)
Immunity
, vol.20
, pp. 695-705
-
-
Hawiger, D.1
Masilamani, R.F.2
Bettelli, E.3
Kuchroo, V.K.4
Nussenzweig, M.C.5
-
8
-
-
12144286596
-
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
-
10.1084/jem.20032220 2212731 15024047
-
Bonifaz LC Bonnyay DP Charalambous A Darguste DI Fujii S Soares H Brimnes MK Moltedo B Moran TM Steinman RM In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination J Exp Med 2004, 199:815-824. 10.1084/jem.20032220 2212731 15024047
-
(2004)
J Exp Med
, vol.199
, pp. 815-824
-
-
Bonifaz, L.C.1
Bonnyay, D.P.2
Charalambous, A.3
Darguste, D.I.4
Fujii, S.5
Soares, H.6
Brimnes, M.K.7
Moltedo, B.8
Moran, T.M.9
Steinman, R.M.10
-
9
-
-
40649097299
-
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine
-
10.1073/pnas.0711976105 2268178 18256187
-
Trumpfheller C Caskey M Nchinda G Longhi MP Mizenina O Huang Y Schlesinger SJ Colonna M Steinman RM The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine Proc Natl Acad Sci USA 2008, 105:2574-2579. 10.1073/pnas.0711976105 2268178 18256187
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2574-2579
-
-
Trumpfheller, C.1
Caskey, M.2
Nchinda, G.3
Longhi, M.P.4
Mizenina, O.5
Huang, Y.6
Schlesinger, S.J.7
Colonna, M.8
Steinman, R.M.9
-
10
-
-
33645048192
-
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine
-
10.1084/jem.20052005 2118242 16505141
-
Trumpfheller C Finke JS Lopez CB Moran TM Moltedo B Soares H Huang Y Schlesinger SJ Park CG Nussenzweig MC Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine J Exp Med 2006, 203:607-617. 10.1084/jem.20052005 2118242 16505141
-
(2006)
J Exp Med
, vol.203
, pp. 607-617
-
-
Trumpfheller, C.1
Finke, J.S.2
Lopez, C.B.3
Moran, T.M.4
Moltedo, B.5
Soares, H.6
Huang, Y.7
Schlesinger, S.J.8
Park, C.G.9
Nussenzweig, M.C.10
-
11
-
-
41849097104
-
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
-
10.1172/JCI34224 2263146 18324335
-
Nchinda G Kuroiwa J Oks M Trumpfheller C Park CG Huang Y Hannaman D Schlesinger SJ Mizenina O Nussenzweig MC et al The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells J Clin Invest 2008, 118:1427-1436. 10.1172/JCI34224 2263146 18324335
-
(2008)
J Clin Invest
, vol.118
, pp. 1427-1436
-
-
Nchinda, G.1
Kuroiwa, J.2
Oks, M.3
Trumpfheller, C.4
Park, C.G.5
Huang, Y.6
Hannaman, D.7
Schlesinger, S.J.8
Mizenina, O.9
Nussenzweig, M.C.10
-
12
-
-
31144448173
-
Rational design of gene-based vaccines
-
10.1002/path.1874 16362986
-
Barouch DH Rational design of gene-based vaccines J Pathol 2006, 208:283-289. 10.1002/path.1874 16362986
-
(2006)
J Pathol
, vol.208
, pp. 283-289
-
-
Barouch, D.H.1
-
13
-
-
58149204280
-
Lessons from IAVI-006, a Phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers
-
Fast P IAVI-006 Study Group 10.1016/j.vaccine.2008.09.016 18812202
-
Guimaraes-Walker A Mackie N McCormack S Hanke T Schmidt C Gilmour J Barin B McMichael A Weber J Legg K Babiker A Hayes P Gotch F Smith C Dally L Dorrell L Cebere I Kay R Winstone N Moore S Goonetilleke N Fast P IAVI-006 Study Group Lessons from IAVI-006, a Phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers Vaccine 2008, 26(51):6671-7. 10.1016/j.vaccine.2008.09.016 18812202
-
(2008)
Vaccine
, vol.26
, Issue.51
, pp. 6671-6677
-
-
Guimaraes-Walker, A.1
Mackie, N.2
McCormack, S.3
Hanke, T.4
Schmidt, C.5
Gilmour, J.6
Barin, B.7
McMichael, A.8
Weber, J.9
Legg, K.10
Babiker, A.11
Hayes, P.12
Gotch, F.13
Smith, C.14
Dally, L.15
Dorrell, L.16
Cebere, I.17
Kay, R.18
Winstone, N.19
Moore, S.20
Goonetilleke, N.21
Fast, P.22
more..
-
14
-
-
44749088148
-
EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone
-
10.1016/j.vaccine.2008.02.072 18502003
-
McCormack S Stohr W Barber T Bart PA Harari A Moog C Ciuffreda D Cellerai C Cowen M Gamboni R et al EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone Vaccine 2008, 26:3162-3174. 10.1016/j.vaccine.2008.02.072 18502003
-
(2008)
Vaccine
, vol.26
, pp. 3162-3174
-
-
McCormack, S.1
Stohr, W.2
Barber, T.3
Bart, P.A.4
Harari, A.5
Moog, C.6
Ciuffreda, D.7
Cellerai, C.8
Cowen, M.9
Gamboni, R.10
-
15
-
-
38749132973
-
An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
-
10.1084/jem.20071331 2234371 18195071
-
Harari A Bart PA Stohr W Tapia G Garcia M Medjitna-Rais E Burnet S Cellerai C Erlwein O Barber T et al An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses J Exp Med 2008, 205:63-77. 10.1084/jem.20071331 2234371 18195071
-
(2008)
J Exp Med
, vol.205
, pp. 63-77
-
-
Harari, A.1
Bart, P.A.2
Stohr, W.3
Tapia, G.4
Garcia, M.5
Medjitna-Rais, E.6
Burnet, S.7
Cellerai, C.8
Erlwein, O.9
Barber, T.10
-
16
-
-
42549087807
-
Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity
-
10.1186/1471-2172-9-13 2324072 18405363
-
Tenbusch M Kuate S Tippler B Gerlach N Schimmer S Dittmer U Uberla K Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity BMC Immunol 2008, 9:13. 10.1186/1471-2172-9-13 2324072 18405363
-
(2008)
BMC Immunol
, vol.9
, pp. 13
-
-
Tenbusch, M.1
Kuate, S.2
Tippler, B.3
Gerlach, N.4
Schimmer, S.5
Dittmer, U.6
Uberla, K.7
-
17
-
-
13644250074
-
Production of lentiviral vectors by transient expression of minimal packaging genes from recombinant adenoviruses
-
10.1002/jgm.623 15459964
-
Kuate S Stefanou D Hoffmann D Wildner O Uberla K Production of lentiviral vectors by transient expression of minimal packaging genes from recombinant adenoviruses J Gene Med 2004, 6:1197-1205. 10.1002/ jgm.623 15459964
-
(2004)
J Gene Med
, vol.6
, pp. 1197-1205
-
-
Kuate, S.1
Stefanou, D.2
Hoffmann, D.3
Wildner, O.4
Uberla, K.5
-
18
-
-
36349021461
-
Atraumatic oral spray immunization with replication-deficient viral vector vaccines
-
10.1128/JVI.01400-07 2169087 17898066
-
Stahl-Hennig C Kuate S Franz M Suh YS Stoiber H Sauermann U Tenner-Racz K Norley S Park KS Sung YC Steinman R Racz P Uberla K Atraumatic oral spray immunization with replication-deficient viral vector vaccines J Virol 2007, 81:13180-13190. 10.1128/JVI.01400-07 2169087 17898066
-
(2007)
J Virol
, vol.81
, pp. 13180-13190
-
-
Stahl-Hennig, C.1
Kuate, S.2
Franz, M.3
Suh, Y.S.4
Stoiber, H.5
Sauermann, U.6
Tenner-Racz, K.7
Norley, S.8
Park, K.S.9
Sung, Y.C.10
Steinman, R.11
Racz, P.12
Uberla, K.13
-
19
-
-
32444446901
-
Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines
-
10.1128/JVI.80.4.1762-1772.2006 1367159 16439533
-
Stone GW Barzee S Snarsky V Kee K Spina CA Yu XF Kornbluth RS Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines J Virol 2006, 80:1762-1772. 10.1128/ JVI.80.4.1762-1772.2006 1367159 16439533
-
(2006)
J Virol
, vol.80
, pp. 1762-1772
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
Kee, K.4
Spina, C.A.5
Yu, X.F.6
Kornbluth, R.S.7
-
20
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
10.1016/S0022-1759(03)00265-5 14580882
-
Betts MR Brenchley JM Price DA De Rosa SC Douek DC Roederer M Koup RA Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation J Immunol Methods 2003, 281:65-78. 10.1016/S0022-1759(03)00265-5 14580882
-
(2003)
J Immunol Methods
, vol.281
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
De Rosa, S.C.4
Douek, D.C.5
Roederer, M.6
Koup, R.A.7
-
21
-
-
17644419950
-
T cell vaccines for microbial infections
-
10.1038/nm1212 15812486
-
Robinson HL Amara RR T cell vaccines for microbial infections Nat Med 2005, 11:S25-S32. 10.1038/nm1212 15812486
-
(2005)
Nat Med
, vol.11
-
-
Robinson, H.L.1
Amara, R.R.2
-
22
-
-
33745224089
-
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
-
10.1038/nature04790 16778891
-
Williams MA Tyznik AJ Bevan MJ Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells Nature 2006, 441:890-893. 10.1038/nature04790 16778891
-
(2006)
Nature
, vol.441
, pp. 890-893
-
-
Williams, M.A.1
Tyznik, A.J.2
Bevan, M.J.3
-
23
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
10.1038/nm1589 17479101
-
Kanzler H Barrat FJ Hessel EM Coffman RL Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists Nat Med 2007, 13:552-559. 10.1038/nm1589 17479101
-
(2007)
Nat Med
, vol.13
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
24
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
-
10.1073/pnas.0407639101 535396 15563593
-
Andrejeva J Childs KS Young DF Carlos TS Stock N Goodbourn S Randall RE The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter Proc Natl Acad Sci USA 2004, 101:17264-17269. 10.1073/pnas.0407639101 535396 15563593
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
Goodbourn, S.6
Randall, R.E.7
-
25
-
-
34248672889
-
Antiviral signaling through pattern recognition receptors
-
10.1093/jb/mvm032 17190786
-
Kawai T Akira S Antiviral signaling through pattern recognition receptors J Biochem 2007, 141:137-145. 10.1093/jb/mvm032 17190786
-
(2007)
J Biochem
, vol.141
, pp. 137-145
-
-
Kawai, T.1
Akira, S.2
-
26
-
-
41149096579
-
T-cell quality in memory and protection: Implications for vaccine design
-
10.1038/nri2274 18323851
-
Seder RA Darrah PA Roederer M T-cell quality in memory and protection: implications for vaccine design Nat Rev Immunol 2008, 8:247-258. 10.1038/ nri2274 18323851
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 247-258
-
-
Seder, R.A.1
Darrah, P.A.2
Roederer, M.3
-
27
-
-
31144448173
-
Rational design of gene-based vaccines
-
10.1002/path.1874 16362986
-
Barouch DH Rational design of gene-based vaccines J Pathol 2006, 208:283-289. 10.1002/path.1874 16362986
-
(2006)
J Pathol
, vol.208
, pp. 283-289
-
-
Barouch, D.H.1
-
28
-
-
66149086978
-
A Novel Cardiotropic Murine Adenovirus Representing a Distinct Species of Mastadenoviruses
-
10.1128/JVI.02281-08 19297486
-
Klempa B Kruger DH Auste B Stanko M Krawczyk A Nickel KF Uberla K Stang A A Novel Cardiotropic Murine Adenovirus Representing a Distinct Species of Mastadenoviruses J Virol 2009, 83(11):5749-59. 10.1128/JVI.02281-08 19297486
-
(2009)
J Virol
, vol.83
, Issue.11
, pp. 5749-5759
-
-
Klempa, B.1
Kruger, D.H.2
Auste, B.3
Stanko, M.4
Krawczyk, A.5
Nickel, K.F.6
Uberla, K.7
Stang, A.8
-
29
-
-
43949114521
-
Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation
-
10.1128/JVI.02564-07 2395223 18353952
-
Liu J Kjeken R Mathiesen I Barouch DH Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation J Virol 2008, 82:5643-5649. 10.1128/JVI.02564-07 2395223 18353952
-
(2008)
J Virol
, vol.82
, pp. 5643-5649
-
-
Liu, J.1
Kjeken, R.2
Mathiesen, I.3
Barouch, D.H.4
-
30
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
10.1038/ni1223 15995707
-
Napolitani G Rinaldi A Bertoni F Sallusto F Lanzavecchia A Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells Nat Immunol 2005, 6:769-776. 10.1038/ni1223 15995707
-
(2005)
Nat Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
31
-
-
49249128648
-
Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12
-
10.1158/0008-5472.CAN-07-6669 18519662
-
Zheng R Cohen PA Paustian CA Johnson TD Lee WT Shu S Koski GK Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12 Cancer Res 2008, 68:4045-4049. 10.1158/ 0008-5472.CAN-07-6669 18519662
-
(2008)
Cancer Res
, vol.68
, pp. 4045-4049
-
-
Zheng, R.1
Cohen, P.A.2
Paustian, C.A.3
Johnson, T.D.4
Lee, W.T.5
Shu, S.6
Koski, G.K.7
-
32
-
-
55849138791
-
Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines
-
10.1073/pnas.0805325105 2570973 18845682
-
Zhu Q Egelston C Vivekanandhan A Uematsu S Akira S Klinman DM Belyakov IM Berzofsky JA Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines Proc Natl Acad Sci USA 2008, 105:16260-16265. 10.1073/ pnas.0805325105 2570973 18845682
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16260-16265
-
-
Zhu, Q.1
Egelston, C.2
Vivekanandhan, A.3
Uematsu, S.4
Akira, S.5
Klinman, D.M.6
Belyakov, I.M.7
Berzofsky, J.A.8
|