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Volumn 780, Issue , 2011, Pages 161-174

Influenza vaccines: What do we want and how can we get it?

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM HYDROXIDE; ALUMINUM PHOSPHATE; AS 03; CD40 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; IC 31; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; MIFAMURTIDE; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG;

EID: 80053596320     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-5632-3_13     Document Type: Conference Paper
Times cited : (7)

References (64)
  • 1
    • 33747161889 scopus 로고    scopus 로고
    • Influenza pandemic vaccines: How to ensure a low-cost, low-dose option
    • DOI 10.1038/nrmicro1482, PII NRMICRO1482
    • Stohr K, Kieny MP, Wood D (2006) Influenza pandemic vaccines: how to ensure a low-cost, low-dose option. Nat Rev Microbiol 4:565-566 (Pubitemid 44317018)
    • (2006) Nature Reviews Microbiology , vol.4 , Issue.8 , pp. 565-566
    • Stohr, K.1    Kieny, M.-P.2    Wood, D.3
  • 2
    • 0036514779 scopus 로고    scopus 로고
    • Updating the accounts: Global mortality of the 1918-1920 "Spanish" influenza pandemic
    • Johnson NP, Mueller J (2002) Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic. Bull Hist Med 76:105-115
    • (2002) Bull Hist Med , vol.76 , pp. 105-115
    • Johnson, N.P.1    Mueller, J.2
  • 6
    • 0037037542 scopus 로고    scopus 로고
    • CD4 effector T cell subsets in the response to influenza: Heterogeneity, migration, and function
    • Roman E, Miller E, Harmsen A, Wiley J, Von Andrian UH, Huston G, Swain SL (2002) CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function. J Exp Med 196:957-968
    • (2002) J Exp Med , vol.196 , pp. 957-968
    • Roman, E.1    Miller, E.2    Harmsen, A.3    Wiley, J.4    Von Andrian, U.H.5    Huston, G.6    Swain, S.L.7
  • 8
    • 67649297821 scopus 로고    scopus 로고
    • Emergence and pandemic potential of swine-origin H1N1 influenza virus
    • Neumann G, Noda T, Kawaoka Y (2009) Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature 459:931-939
    • (2009) Nature , vol.459 , pp. 931-939
    • Neumann, G.1    Noda, T.2    Kawaoka, Y.3
  • 9
    • 26444506691 scopus 로고    scopus 로고
    • Characterization of the 1918 influenza virus polymerase genes
    • DOI 10.1038/nature04230, PII N04230
    • Taubenberger JK, Reid AH, Lourens RM, Wang R, Jin G, Fanning TG (2005) Characterization of the 1918 influenza virus polymerase genes. Nature 437:889-893 (Pubitemid 41486764)
    • (2005) Nature , vol.437 , Issue.7060 , pp. 889-893
    • Taubenberger, J.K.1    Reid, A.H.2    Lourens, R.M.3    Wang, R.4    Jin, G.5    Fanning, T.G.6
  • 11
    • 84856019966 scopus 로고    scopus 로고
    • access May 20, 2011
    • http://www.who.int/csr/disease/avian-influenza/country/ cases-table-2011-05-13/en/index. html (access May 20, 2011)
  • 13
    • 33750286032 scopus 로고    scopus 로고
    • Vaccines for seasonal and pandemic influenza
    • DOI 10.1086/507544
    • Nichol KL, Treanor JJ (2006) Vaccines for seasonal and pandemic influenza. J Infect Dis 194(Suppl 2):S111-S118 (Pubitemid 44630954)
    • (2006) Journal of Infectious Diseases , vol.194 , Issue.SUPPL. 2
    • Nichol, K.L.1    Treanor, J.J.2
  • 14
    • 0001358564 scopus 로고    scopus 로고
    • History of inactivated influenza vaccines
    • Nicholson KG, Webster RG, Hay AJ (eds). Blackwell Science, Oxford
    • Wood JM, Williams MS (1998) History of inactivated influenza vaccines. In: Nicholson KG, Webster RG, Hay AJ (eds) Textbook of Influenza. Blackwell Science, Oxford, pp 317-323
    • (1998) Textbook of Influenza , pp. 317-323
    • Wood, J.M.1    Williams, M.S.2
  • 17
    • 73149120237 scopus 로고    scopus 로고
    • Safety and immunogenicity of a 2009 pandemic influenza A H1N1 vaccine when administered alone or simultaneously with the seasonal influenza vaccine for the 2009-10 influenza season: A multicentre, randomised controlled trial
    • Vajo Z, Tamas F, Sinka L, Jankovics I (2010) Safety and immunogenicity of a 2009 pandemic influenza A H1N1 vaccine when administered alone or simultaneously with the seasonal influenza vaccine for the 2009-10 influenza season: a multicentre, randomised controlled trial. Lancet 375:49-55
    • (2010) Lancet , vol.375 , pp. 49-55
    • Vajo, Z.1    Tamas, F.2    Sinka, L.3    Jankovics, I.4
  • 19
    • 67650670745 scopus 로고    scopus 로고
    • Pre-pandemic H5N1 influenza vaccine adjuvanted with AS03: A review of the pre-clinical and clinical data
    • Leroux-Roels G (2009) Pre-pandemic H5N1 influenza vaccine adjuvanted with AS03: a review of the pre-clinical and clinical data. Expert Opin Biol Ther 9:1057-1071
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 1057-1071
    • Leroux-Roels, G.1
  • 21
    • 0031930630 scopus 로고    scopus 로고
    • Comparison of serology and reactogenicity between influenza subunit vaccines and whole virus or split vaccines. A review and meta-analysis of the literature
    • DOI 10.2165/00044011-199815010-00001
    • Beyer WE, Palache AM, Osterhaus AD (1998) Comparison of serology and reactogenicity between influenza sub-unit vaccines and whole virus or split vaccines: a review and metaanalysis of the literature. Clin Drug Investig 15:1-12 (Pubitemid 28073487)
    • (1998) Clinical Drug Investigation , vol.15 , Issue.1 , pp. 1-12
    • Beyer, W.E.P.1    Palache, A.M.2    Osterhaus, A.D.M.E.3
  • 22
    • 0018743525 scopus 로고
    • Clinical studies of monovalent inactivated whole virus and subunit A/USSR/77 (H1N1) vaccine: Serological responses and clinical reactions
    • Nicholson KG, Tyrrell DA, Harrison P, Potter CW, Jennings R, Clark A, Schild GC, Wood JM, Yetts R, Seagroatt V, Huggins A, Anderson SG (1979) Clinical studies of monovalent inactivated whole virus and sub-unit A/USSR/77 (H1N1) vaccine: serological responses and clinical reactions. J Biol Stand 7:123-136 (Pubitemid 9149059)
    • (1979) Journal of Biological Standardization , vol.7 , Issue.2 , pp. 123-136
    • Nicholson, K.G.1    Tyrrell, D.A.J.2    Harrison, P.3
  • 23
    • 10744232673 scopus 로고    scopus 로고
    • Safety and antigenicity of whole virus and subunit influenza A/Hong Kong/1073/99 (H9N2) vaccine in healthy adults: Phase I randomised trial
    • DOI 10.1016/S0140-6736(03)15014-3
    • Stephenson I, Nicholson KG, Gliick R, Mischler R, Newman RW, Palache AM, Verlander NQ, Warburton F, Wood JM, Zambon MC (2003) Safety and antigenicity of whole virus and sub-unit influenza A/Hong Kong/1073/99 (H9N2) vaccine in healthy adults: phase I randomised trial. Lancet 362:1959-1966 (Pubitemid 37548419)
    • (2003) Lancet , vol.362 , Issue.9400 , pp. 1959-1966
    • Stephenson, I.1    Nicholson, K.G.2    Gluck, R.3    Mischler, R.4    Newman, R.W.5    Palache, A.M.6    Verlander, N.Q.7    Warburton, F.8    Wood, J.M.9    Zambon, M.C.10
  • 24
    • 84856019967 scopus 로고    scopus 로고
    • access May 20, 2011)
    • http://www.who.int/vaccine-research/diseases/influenza/flu-trials-tables/ en (access May 20, 2011)
  • 25
    • 27644492741 scopus 로고    scopus 로고
    • Two doses of parenterally administered split influenza virus vaccine elicited high serum IgG concentrations which effectively limited viral shedding upon challenge in mice
    • DOI 10.1111/j.1365-3083.2005.01666.x
    • Hovden AO, Cox RJ, Madhun A, Haaheim LR (2005) Two doses of parenterally administered split influenza virus vaccine elicited high serum IgG concentrations which effectively limited viral shedding upon challenge in mice. Scand J Immunol 62:342-352 (access May 20, 2011) (Pubitemid 41565386)
    • (2005) Scandinavian Journal of Immunology , vol.62 , Issue.4 , pp. 342-352
    • Hovden, A.-O.1    Cox, R.J.2    Madhun, A.3    Haaheim, L.R.4
  • 26
    • 42649093469 scopus 로고    scopus 로고
    • Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection
    • Bungener L, Geeraedts F, Ter Veer W, Medema J, Wilschut J, Huckriede A (2008) Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection. Vaccine 26:2350-2359
    • (2008) Vaccine , vol.26 , pp. 2350-2359
    • Bungener, L.1    Geeraedts, F.2    Ter Veer, W.3    Medema, J.4    Wilschut, J.5    Huckriede, A.6
  • 27
    • 58149197779 scopus 로고    scopus 로고
    • Head-to-head comparison of four nonadju-vanted inactivated cell culture-derived influenza vaccines: Effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model
    • Hagenaars N, Mastrobattista E, Glansbeek H, Heldens J, van den Bosch H, Schijns V, Betbeder D, Vromans H, Jiskoot W (2008) Head-to-head comparison of four nonadju-vanted inactivated cell culture-derived influenza vaccines: effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model. Vaccine 26:6555-6563
    • (2008) Vaccine , vol.26 , pp. 6555-6563
    • Hagenaars, N.1    Mastrobattista, E.2    Glansbeek, H.3    Heldens, J.4    Van Den Bosch, H.5    Schijns, V.6    Betbeder, D.7    Vromans, H.8    Jiskoot, W.9
  • 28
    • 22644447284 scopus 로고    scopus 로고
    • Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice
    • DOI 10.1111/j.1365-3083.2005.01633.x
    • Hovden AO, Cox RJ, Haaheim LR (2005) Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice. Scand J Immunol 62:36-44 (Pubitemid 41025876)
    • (2005) Scandinavian Journal of Immunology , vol.62 , Issue.1 , pp. 36-44
    • Hovden, A.-O.1    Cox, R.J.2    Haaheim, L.R.3
  • 29
    • 50849107415 scopus 로고    scopus 로고
    • Whole inactivated virus influenza vaccine is superior to sub-unit vaccine in inducing immune responses and secretion of pro-inflammatory cytokines by DCs
    • Geeraedts F, Bungener L, Pool J, ter Veer W, Wilschut J, Huckriede A (2008) Whole inactivated virus influenza vaccine is superior to sub-unit vaccine in inducing immune responses and secretion of pro-inflammatory cytokines by DCs. Influenza Other Respi Viruses 2:41-51
    • (2008) Influenza Other Respi Viruses , vol.2 , pp. 41-51
    • Geeraedts, F.1    Bungener, L.2    Pool, J.3    Ter Veer, W.4    Wilschut, J.5    Huckriede, A.6
  • 32
    • 0031731738 scopus 로고    scopus 로고
    • Whole virus influenza vaccine activates dendritic cells (DC) and stimulates cytokine production by peripheral blood mononuclear cells (PBMC) while subunit vaccines support T cell proliferation
    • DOI 10.1046/j.1365-2249.1998.00714.x
    • Saurwein-Teissl M, Zisterer K, Schmitt TL, Gliick R, Cryz S, Grubeck-Loebenstein B (1998) Whole virus influenza vaccine activates dendritic cells (DC) and stimulates cytokine production by peripheral blood mononuclear cells (PBMC) while sub-unit vaccines support T cell proliferation. Clin Exp Immunol 114:271-276 (Pubitemid 28505729)
    • (1998) Clinical and Experimental Immunology , vol.114 , Issue.2 , pp. 271-276
    • Saurwein-Teissl, M.1    Zisterer, K.2    Schmitt, T.L.3    Gluck, R.4    Cryz, S.5    Grubeck-Loebenstein, B.6
  • 35
    • 0035030376 scopus 로고    scopus 로고
    • Type i inter-ferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF (2001) Type I inter-ferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14:461-170
    • (2001) Immunity , vol.14 , pp. 461-170
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 36
    • 33646027625 scopus 로고    scopus 로고
    • Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection
    • Coro ES, Chang WL, Baumgarth N (2006) Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection. J Immunol 176:4343-4351 (Pubitemid 44264414)
    • (2006) Journal of Immunology , vol.176 , Issue.7 , pp. 4343-4351
    • Coro, E.S.1    Chang, W.L.W.2    Baumgarth, N.3
  • 37
    • 33846526235 scopus 로고    scopus 로고
    • Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals
    • Chang WL, Coro ES, Rau FC, Xiao Y, Erle DJ, Baumgarth N (2007) Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals. J Immunol 178:1457-1467 (Pubitemid 46154617)
    • (2007) Journal of Immunology , vol.178 , Issue.3 , pp. 1457-1467
    • Chang, W.L.W.1    Coro, E.S.2    Rau, F.C.3    Xiao, Y.4    Erle, D.J.5    Baumgarth, N.6
  • 38
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • DOI 10.1126/science.1093616
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529-1531 (Pubitemid 38314425)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis E Sousa, C.5
  • 39
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, Hartmann G (2002) Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168:4531-4537 (Pubitemid 34441357)
    • (2002) Journal of Immunology , vol.168 , Issue.9 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 40
    • 70249097764 scopus 로고    scopus 로고
    • B cell intrinsic MyD88 signals drive IFN- gamma production from T cells and control switching to IgG2c
    • Barr TA, Brown S, Mastroeni P, Gray D (2009) B cell intrinsic MyD88 signals drive IFN- gamma production from T cells and control switching to IgG2c. J Immunol 183:1005-1012
    • (2009) J Immunol , vol.183 , pp. 1005-1012
    • Barr, T.A.1    Brown, S.2    Mastroeni, P.3    Gray, D.4
  • 41
    • 33846937311 scopus 로고    scopus 로고
    • TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
    • Heer AK, Shamshiev A, Donda A, Uematsu S, Akira S, Kopf M, Marsland BJ (2007) TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J Immunol 178:2182-2191 (Pubitemid 46233416)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2182-2191
    • Heer, A.K.1    Shamshiev, A.2    Donda, A.3    Uematsu, S.4    Akira, S.5    Kopf, M.6    Marsland, B.J.7
  • 43
    • 77649179583 scopus 로고    scopus 로고
    • Production of H5N1 (NIBRG-14) inactivated whole virus and split virion influenza vaccines and analysis of immunogenicity in mice using different adjuvant formulations
    • Miyaki C, Quintilio W, Miyaji EN, Botosso VF, Kubrusly FS, Santos FL, Iourtov D, Higashi HG, Raw I (2010) Production of H5N1 (NIBRG-14) inactivated whole virus and split virion influenza vaccines and analysis of immunogenicity in mice using different adjuvant formulations. Vaccine 28:2505-2509
    • (2010) Vaccine , vol.28 , pp. 2505-2509
    • Miyaki, C.1    Quintilio, W.2    Miyaji, E.N.3    Botosso, V.F.4    Kubrusly, F.S.5    Santos, F.L.6    Iourtov, D.7    Higashi, H.G.8    Raw, I.9
  • 44
    • 77953124392 scopus 로고    scopus 로고
    • Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine
    • Skountzou I, Martin MP, Wang B, Ye L, Koutsonanos D, Weldon W, Jacob J, Compans RW (2010) Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine. Vaccine 28:4103-4112
    • (2010) Vaccine , vol.28 , pp. 4103-4112
    • Skountzou, I.1    Martin, M.P.2    Wang, B.3    Ye, L.4    Koutsonanos, D.5    Weldon, W.6    Jacob, J.7    Compans, R.W.8
  • 46
    • 44749084178 scopus 로고    scopus 로고
    • The novel adjuvant IC31 strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice
    • Riedl K, Riedl R, von Gabain A, Nagy E, Lingnau K (2008) The novel adjuvant IC31 strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice. Vaccine 26:3461-3468
    • (2008) Vaccine , vol.26 , pp. 3461-3468
    • Riedl, K.1    Riedl, R.2    Von Gabain, A.3    Nagy, E.4    Lingnau, K.5
  • 47
    • 84856003127 scopus 로고    scopus 로고
    • (accessed May 20, 2011)
    • http://www.intercell.com/main/forvaccperts/products/ic31R-seasonal- influenza-vaccine (accessed May 20, 2011)
  • 48
    • 0037205082 scopus 로고    scopus 로고
    • Workshop summary aluminum in vaccines
    • Eickhoff TC, Myers M (2002) Workshop summary. aluminum in vaccines. Vaccine 20(Suppl 3):S1-S4
    • (2002) Vaccine , vol.20 SUPPL. 3
    • Eickhoff, T.C.1    Myers, M.2
  • 49
    • 63149126030 scopus 로고    scopus 로고
    • Towards an understanding of the adjuvant action of aluminium
    • Marrack P, McKee AS, Munks MW (2009) Towards an understanding of the adjuvant action of aluminium. Nat Rev Immunol 9:287-293
    • (2009) Nat Rev Immunol , vol.9 , pp. 287-293
    • Marrack, P.1    McKee, A.S.2    Munks, M.W.3
  • 50
    • 73949107102 scopus 로고    scopus 로고
    • Vaccines for pandemic influenza: Summary of recent clinical trials
    • Keitel WA, Atmar RL (2009) Vaccines for pandemic influenza: summary of recent clinical trials. Curr Top Microbiol Immunol 333:431-451
    • (2009) Curr Top Microbiol Immunol , vol.333 , pp. 431-451
    • Keitel, W.A.1    Atmar, R.L.2
  • 51
    • 84856003128 scopus 로고    scopus 로고
    • accessed May 20, 2011)
    • http://www.who.int/vaccine-research/diseases/influenza/flu-trials-tables/ en/index.html (accessed May 20, 2011)
  • 52
    • 84856003129 scopus 로고    scopus 로고
    • (accessed May 20, 2011)
    • http://ecdc.europa.eu/en/healthtopics/documents/0911-pandemic-influenza- (h1n1)-qa-on- vaccines-and-vaccination-experts.pdf (accessed May 20, 2011)
  • 53
    • 34147181229 scopus 로고    scopus 로고
    • Inactivated influenza H5N1 whole-virus vaccine with aluminum adjuvant induces homologous and heterologous protective immunities against lethal challenge with highly pathogenic H5N1 avian influenza viruses in a mouse model
    • DOI 10.1016/j.vaccine.2007.01.083, PII S0264410X07001120
    • Ninomiya A, Imai M, Tashiro M, Odagiri T (2007) Inactivated influenza H5N1 whole-virus vaccine with aluminum adjuvant induces homologous and heterologous protective immunities against lethal challenge with highly pathogenic H5N1 avian influenza viruses in a mouse model. Vaccine 25:3554-3560 (Pubitemid 46575102)
    • (2007) Vaccine , vol.25 , Issue.18 , pp. 3554-3560
    • Ninomiya, A.1    Imai, M.2    Tashiro, M.3    Odagiri, T.4
  • 55
    • 0035897889 scopus 로고    scopus 로고
    • Safety and antigenicity of non-adjuvanted and MF59-adjuvanted influenza A/Duck/Singapore/97 (H5N3) vaccine: A randomised trial of two potential vaccines against H5N1 influenza
    • DOI 10.1016/S0140-6736(00)05066-2
    • Nicholson KG, Colegate AE, Podda A, Stephenson I, Wood J, Ypma E, Zambon MC (2001) Safety and antigenicity of non-adjuvanted and MF59-adjuvanted influenza A/Duck/ Singapore/97 (H5N3) vaccine: a randomised trial of two potential vaccines against H5N1 influenza. Lancet 357:1937-1943 (Pubitemid 32568336)
    • (2001) Lancet , vol.357 , Issue.9272 , pp. 1937-1943
    • Nicholson, K.G.1    Colegate, A.E.2    Podda, A.3    Stephenson, I.4    Wood, J.5    Ypma, E.6    Zambon, M.C.7
  • 56
    • 17044380507 scopus 로고    scopus 로고
    • Cross-reactivity to highly pathogenic avian influenza H5N1 viruses after vaccination with non-adjuvanted and MF59-adjuvanted influenza /Duck/Singapore/97 (H5N3) vaccine: A potential priming strategy
    • Stephenson I, Bugarini R, Nicholson KG, Podda A, Wood JM, Zambon MC, Katz JM (2005) Cross-reactivity to highly pathogenic avian influenza H5N1 viruses after vaccination with non-adjuvanted and MF59-adjuvanted influenza /Duck/Singapore/97 (H5N3) vaccine: a potential priming strategy. J Infect Dis 191:1210-1215
    • (2005) J Infect Dis , vol.191 , pp. 1210-1215
    • Stephenson, I.1    Bugarini, R.2    Nicholson, K.G.3    Podda, A.4    Wood, J.M.5    Zambon, M.C.6    Katz, J.M.7
  • 59
    • 67349269509 scopus 로고    scopus 로고
    • Mechanism of action of licensed vaccine adjuvants
    • Tritto E, Mosca F, De Gregorio E (2009) Mechanism of action of licensed vaccine adjuvants. Vaccine 27:3331-3334
    • (2009) Vaccine , vol.27 , pp. 3331-3334
    • Tritto, E.1    Mosca, F.2    De Gregorio, E.3


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