-
1
-
-
79957953215
-
Principles of activation and permeation in an anion-selective cys-loop receptor
-
21572436 10.1038/nature10139 1:CAS:528:DC%2BC3MXmsFyqt7Y%3D
-
Hibbs RE, Gouaux E (2011) Principles of activation and permeation in an anion-selective cys-loop receptor. Nature 474:54-60
-
(2011)
Nature
, vol.474
, pp. 54-60
-
-
Hibbs, R.E.1
Gouaux, E.2
-
2
-
-
79951674390
-
The structural basis of function in cys-loop receptors
-
20849671 10.1017/S0033583510000168 1:CAS:528:DC%2BC3cXhsVGitbfL
-
Thompson AJ, Lester HA, Lummis SC (2010) The structural basis of function in cys-loop receptors. Q Rev Biophys 43:449-499
-
(2010)
Q Rev Biophys
, vol.43
, pp. 449-499
-
-
Thompson, A.J.1
Lester, H.A.2
Lummis, S.C.3
-
3
-
-
77949538692
-
Atomic structure and dynamics of pentameric ligand-gated ion channels: New insight from bacterial homologues
-
19995852 10.1113/jphysiol.2009.183160 1:CAS:528:DC%2BC3cXisVeksL0%3D
-
Corringer PJ, Baaden M, Bocquet N, Delarue M, Dufresne V, Nury H, Prevost M, Van Renterghem C (2010) Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues. J Physiol 588:565-572
-
(2010)
J Physiol
, vol.588
, pp. 565-572
-
-
Corringer, P.J.1
Baaden, M.2
Bocquet, N.3
Delarue, M.4
Dufresne, V.5
Nury, H.6
Prevost, M.7
Van Renterghem, C.8
-
4
-
-
69249088472
-
A prokaryotic perspective on pentameric ligand-gated ion channel structure
-
19646860 10.1016/j.sbi.2009.07.006 1:CAS:528:DC%2BD1MXhtVKktbvJ
-
Hilf RJ, Dutzler R (2009) A prokaryotic perspective on pentameric ligand-gated ion channel structure. Curr Opin Struct Biol 19:418-424
-
(2009)
Curr Opin Struct Biol
, vol.19
, pp. 418-424
-
-
Hilf, R.J.1
Dutzler, R.2
-
5
-
-
77950494200
-
Binding, activation and modulation of cys-loop receptors
-
20096941 10.1016/j.tips.2009.12.005 1:CAS:528:DC%2BC3cXjvFKksbg%3D
-
Miller PS, Smart TG (2010) Binding, activation and modulation of cys-loop receptors. Trends Pharmacol Sci 31:161-174
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 161-174
-
-
Miller, P.S.1
Smart, T.G.2
-
6
-
-
0242353157
-
EXP-1 is an excitatory GABA-gated cation channel
-
14555952 10.1038/nn1136 1:CAS:528:DC%2BD3sXosVOiurY%3D
-
Beg AA, Jorgensen EM (2003) EXP-1 is an excitatory GABA-gated cation channel. Nat Neurosci 6:1145-1152
-
(2003)
Nat Neurosci
, vol.6
, pp. 1145-1152
-
-
Beg, A.A.1
Jorgensen, E.M.2
-
7
-
-
0034707063
-
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
-
11100728 10.1038/35044083 1:CAS:528:DC%2BD3cXos1Srtr0%3D
-
Ranganathan R, Cannon SC, Horvitz HR (2000) MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature 408:470-475
-
(2000)
Nature
, vol.408
, pp. 470-475
-
-
Ranganathan, R.1
Cannon, S.C.2
Horvitz, H.R.3
-
8
-
-
0036829880
-
The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA)
-
12196539 10.1074/jbc.M207133200 1:CAS:528:DC%2BD38XotF2gtL8%3D
-
Gengs C, Leung HT, Skingsley DR, Iovchev MI, Yin Z, Semenov EP, Burg MG, Hardie RC, Pak WL (2002) The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA). J Biol Chem 277:42113-42120
-
(2002)
J Biol Chem
, vol.277
, pp. 42113-42120
-
-
Gengs, C.1
Leung, H.T.2
Skingsley, D.R.3
Iovchev, M.I.4
Yin, Z.5
Semenov, E.P.6
Burg, M.G.7
Hardie, R.C.8
Pak, W.L.9
-
9
-
-
1942470079
-
Esophageal foreign body in neonates
-
15129878 1:STN:280:DC%2BD2c3jtVOnuw%3D%3D
-
Tasneem Z, Khan MA, Uddin N (2004) Esophageal foreign body in neonates. J Pak Med Assoc 54:159-161
-
(2004)
J Pak Med Assoc
, vol.54
, pp. 159-161
-
-
Tasneem, Z.1
Khan, M.A.2
Uddin, N.3
-
10
-
-
84965075853
-
A study of the desensitization produced by acetylcholine at the motor end-plate
-
13463799 1:STN:280:DyaG1c%2Fgs1Cmug%3D%3D
-
Katz B, Thesleff S (1957) A study of the desensitization produced by acetylcholine at the motor end-plate. J Physiol 138:63-80
-
(1957)
J Physiol
, vol.138
, pp. 63-80
-
-
Katz, B.1
Thesleff, S.2
-
11
-
-
0031870973
-
Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism
-
9689026 10.1085/jgp.112.2.181 1:CAS:528:DyaK1cXlsVWqsLY%3D
-
Auerbach A, Akk G (1998) Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism. J Gen Physiol 112:181-197
-
(1998)
J Gen Physiol
, vol.112
, pp. 181-197
-
-
Auerbach, A.1
Akk, G.2
-
12
-
-
20744449198
-
Desensitization of nicotinic ACh receptors: Shaping cholinergic signaling
-
15979501 10.1016/j.tins.2005.04.009 1:CAS:528:DC%2BD2MXlsVequ7w%3D
-
Giniatullin R, Nistri A, Yakel J (2005) Desensitization of nicotinic ACh receptors: shaping cholinergic signaling. Trends Neurosci 28:371-378
-
(2005)
Trends Neurosci
, vol.28
, pp. 371-378
-
-
Giniatullin, R.1
Nistri, A.2
Yakel, J.3
-
13
-
-
67549125013
-
Allosteric activation mechanism of the cys-loop receptors
-
19444220 10.1038/aps.2009.51
-
Chang Y-c WW, J-l Z, Huang Y (2009) Allosteric activation mechanism of the cys-loop receptors. Acta Pharmacol Sin 30:663-672
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 663-672
-
-
Chang, Y.-C.W.W.1
Huang, Y.2
-
14
-
-
33746788525
-
An interaction involving an arginine residue in the cytoplasmic domain of the 5-HT3A receptor contributes to receptor desensitization mechanism
-
16754678 10.1074/jbc.M600676200 1:CAS:528:DC%2BD28XnsVOntbY%3D
-
Hu XQ (2006) An interaction involving an arginine residue in the cytoplasmic domain of the 5-HT3A receptor contributes to receptor desensitization mechanism. J Biol Chem 281:21781-21788
-
(2006)
J Biol Chem
, vol.281
, pp. 21781-21788
-
-
Hu, X.Q.1
-
15
-
-
0030025395
-
The impact of receptor desensitization on fast synaptic transmission
-
9054063 10.1016/S0166-2236(96)80037-3 1:CAS:528:DyaK28XhtlSntr0%3D
-
Jones MV, Westbrook GL (1996) The impact of receptor desensitization on fast synaptic transmission. Trends Neurosci 19:96-101
-
(1996)
Trends Neurosci
, vol.19
, pp. 96-101
-
-
Jones, M.V.1
Westbrook, G.L.2
-
16
-
-
0033363317
-
Acetylcholine receptor M3 domain: Stereochemical and volume contributions to channel gating
-
10195214 10.1038/6326 1:CAS:528:DyaK1MXhsl2gu74%3D
-
Wang HL, Milone M, Ohno K, Shen XM, Tsujino A, Batocchi AP, Tonali P, Brengman J, Engel AG, Sine SM (1999) Acetylcholine receptor M3 domain: Stereochemical and volume contributions to channel gating. Nat Neurosci 2:226-233
-
(1999)
Nat Neurosci
, vol.2
, pp. 226-233
-
-
Wang, H.L.1
Milone, M.2
Ohno, K.3
Shen, X.M.4
Tsujino, A.5
Batocchi, A.P.6
Tonali, P.7
Brengman, J.8
Engel, A.G.9
Sine, S.M.10
-
17
-
-
0034932799
-
Acetylcholine receptor delta subunit mutations underlie a fast-channel myasthenic syndrome and arthrogryposis multiplex congenita
-
11435464 1:CAS:528:DC%2BD3MXkvVarsL4%3D
-
Brownlow S, Webster R, Croxen R, Brydson M, Neville B, Lin JP, Vincent A, Newsom-Davis J, Beeson D (2001) Acetylcholine receptor delta subunit mutations underlie a fast-channel myasthenic syndrome and arthrogryposis multiplex congenita. J Clin Invest 108:125-130
-
(2001)
J Clin Invest
, vol.108
, pp. 125-130
-
-
Brownlow, S.1
Webster, R.2
Croxen, R.3
Brydson, M.4
Neville, B.5
Lin, J.P.6
Vincent, A.7
Newsom-Davis, J.8
Beeson, D.9
-
18
-
-
0035057060
-
A single amino-acid in the TM1 domain is an important determinant of the desensitization kinetics of recombinant human and guinea pig alpha-homomeric 5-hydroxytryptamine type 3 receptors
-
11259629 1:CAS:528:DC%2BD3MXisVSqs7o%3D
-
Lobitz N, Gisselmann G, Hatt H, Wetzel CH (2001) A single amino-acid in the TM1 domain is an important determinant of the desensitization kinetics of recombinant human and guinea pig alpha-homomeric 5-hydroxytryptamine type 3 receptors. Mol Pharmacol 59:844-851
-
(2001)
Mol Pharmacol
, vol.59
, pp. 844-851
-
-
Lobitz, N.1
Gisselmann, G.2
Hatt, H.3
Wetzel, C.H.4
-
19
-
-
0023159126
-
Two distinct kinetic phases of desensitization of acetylcholine receptors of clonal rat PC12 cells
-
2445978 1:CAS:528:DyaL2sXkvFSmur8%3D
-
Boyd ND (1987) Two distinct kinetic phases of desensitization of acetylcholine receptors of clonal rat PC12 cells. J Physiol 389:45-67
-
(1987)
J Physiol
, vol.389
, pp. 45-67
-
-
Boyd, N.D.1
-
20
-
-
19444377836
-
Desensitized nicotinic receptors in brain
-
15914250 10.1016/j.brainresrev.2004.09.003 1:CAS:528:DC%2BD2MXks1Cksrs%3D
-
Wang H, Sun X (2005) Desensitized nicotinic receptors in brain. Brain Res Rev 48:420-437
-
(2005)
Brain Res Rev
, vol.48
, pp. 420-437
-
-
Wang, H.1
Sun, X.2
-
21
-
-
0032586886
-
Regulation of alpha4beta2 nicotinic receptor desensitization by calcium and protein kinase C
-
10051526 1:CAS:528:DyaK1MXhslWjtbg%3D
-
Fenster CP, Beckman ML, Parker JC, Sheffield EB, Whitworth TL, Quick MW, Lester RA (1999) Regulation of alpha4beta2 nicotinic receptor desensitization by calcium and protein kinase C. Mol Pharmacol 55:432-443
-
(1999)
Mol Pharmacol
, vol.55
, pp. 432-443
-
-
Fenster, C.P.1
Beckman, M.L.2
Parker, J.C.3
Sheffield, E.B.4
Whitworth, T.L.5
Quick, M.W.6
Lester, R.A.7
-
22
-
-
0025202331
-
Regulation of neurotransmitter receptor desensitization by protein phosphorylation
-
1699566 10.1016/0896-6273(90)90211-W 1:CAS:528:DyaK3MXlt1OjtrY%3D
-
Huganir RL, Greengard P (1990) Regulation of neurotransmitter receptor desensitization by protein phosphorylation. Neuron 5:555-567
-
(1990)
Neuron
, vol.5
, pp. 555-567
-
-
Huganir, R.L.1
Greengard, P.2
-
23
-
-
0034126122
-
Chronic nicotine administration in the drinking water affects the striatal dopamine in mice
-
10837848 10.1016/S0091-3057(00)00235-5 1:CAS:528:DC%2BD3cXjs1Cgu7w%3D
-
Pietila K, Ahtee L (2000) Chronic nicotine administration in the drinking water affects the striatal dopamine in mice. Pharmacol Biochem Behav 66:95-103
-
(2000)
Pharmacol Biochem Behav
, vol.66
, pp. 95-103
-
-
Pietila, K.1
Ahtee, L.2
-
24
-
-
58149267953
-
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
18987633 10.1038/nature07462 1:CAS:528:DC%2BD1MXhtVGhug%3D%3D
-
Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, Corringer PJ (2009) X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 457:111-114
-
(2009)
Nature
, vol.457
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.P.5
Delarue, M.6
Corringer, P.J.7
-
25
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
18987630 10.1038/nature07461 1:CAS:528:DC%2BD1MXhtVGgsA%3D%3D
-
Hilf RJ, Dutzler R (2009) Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel. Nature 457:115-118
-
(2009)
Nature
, vol.457
, pp. 115-118
-
-
Hilf, R.J.1
Dutzler, R.2
-
26
-
-
41149168686
-
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
-
18322461 10.1038/nature06717 1:CAS:528:DC%2BD1cXjsFCnsLw%3D
-
Hilf RJ, Dutzler R (2008) X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature 452:375-379
-
(2008)
Nature
, vol.452
, pp. 375-379
-
-
Hilf, R.J.1
Dutzler, R.2
-
27
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
12827192 10.1038/nature01748 1:CAS:528:DC%2BD3sXkvVKmsrY%3D
-
Miyazawa A, Fujiyoshi Y, Unwin N (2003) Structure and gating mechanism of the acetylcholine receptor pore. Nature 423:949-955
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
28
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
14343300 10.1016/S0022-2836(65)80285-6 1:CAS:528:DyaF2MXkt1Ghsb4%3D
-
Monod J, Wyman J, Changeux JP (1965) On the nature of allosteric transitions: a plausible model. J Mol Biol 12:88-118
-
(1965)
J Mol Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
29
-
-
0014072741
-
On the arginase of the Shope papillomas
-
6022698 10.1016/0042-6822(67)90206-1 1:CAS:528:DyaF2sXhtFansrc%3D
-
Orth G, Vielle F, Changeux JP (1967) On the arginase of the Shope papillomas. Virology 31:729-732
-
(1967)
Virology
, vol.31
, pp. 729-732
-
-
Orth, G.1
Vielle, F.2
Changeux, J.P.3
-
30
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
5938952 10.1021/bi00865a047 1:CAS:528:DyaF28XivVGnsw%3D%3D
-
Koshland DE Jr, Nemethy G, Filmer D (1966) Comparison of experimental binding data and theoretical models in proteins containing subunits. Biochemistry 5:365-385
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland, Jr.D.E.1
Nemethy, G.2
Filmer, D.3
-
31
-
-
79960120380
-
Desensitization of 7 nicotinic receptor is governed by coupling strength relative to gate tightness
-
21610071 10.1074/jbc.M111.221754 1:CAS:528:DC%2BC3MXosFGmtbs%3D
-
Zhang J, Xue F, Whiteaker P, Li C, Wu W, Shen B, Huang Y, Lukas RJ, Chang Y (2011) Desensitization of 7 nicotinic receptor is governed by coupling strength relative to gate tightness. J Biol Chem 286:25331-25340
-
(2011)
J Biol Chem
, vol.286
, pp. 25331-25340
-
-
Zhang, J.1
Xue, F.2
Whiteaker, P.3
Li, C.4
Wu, W.5
Shen, B.6
Huang, Y.7
Lukas, R.J.8
Chang, Y.9
-
32
-
-
77949497067
-
The gating isomerization of neuromuscular acetylcholine receptors
-
19933754 10.1113/jphysiol.2009.182774 1:CAS:528:DC%2BC3cXisVeksLo%3D
-
Auerbach A (2010) The gating isomerization of neuromuscular acetylcholine receptors. J Physiol 588:573-586
-
(2010)
J Physiol
, vol.588
, pp. 573-586
-
-
Auerbach, A.1
-
33
-
-
49649102025
-
On the nature of partial agonism in the nicotinic receptor superfamily
-
18633353 1:CAS:528:DC%2BD1cXps1Snsrg%3D
-
Lape R, Colquhoun D, Sivilotti LG (2008) On the nature of partial agonism in the nicotinic receptor superfamily. Nature 454:722-727
-
(2008)
Nature
, vol.454
, pp. 722-727
-
-
Lape, R.1
Colquhoun, D.2
Sivilotti, L.G.3
-
34
-
-
70349584397
-
Single-channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors
-
19720021 10.1016/j.bpj.2009.06.018 1:CAS:528:DC%2BD1MXhsVCjsrrE
-
Corradi J, Gumilar F, Bouzat C (2009) Single-channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors. Biophys J 97:1335-1345
-
(2009)
Biophys J
, vol.97
, pp. 1335-1345
-
-
Corradi, J.1
Gumilar, F.2
Bouzat, C.3
-
35
-
-
67349279395
-
Detection and trapping of intermediate states priming nicotinic receptor channel opening
-
19339970 10.1038/nature07923 1:CAS:528:DC%2BD1MXjvV2lurY%3D
-
Mukhtasimova N, Lee WY, Wang HL, Sine SM (2009) Detection and trapping of intermediate states priming nicotinic receptor channel opening. Nature 459:451-454
-
(2009)
Nature
, vol.459
, pp. 451-454
-
-
Mukhtasimova, N.1
Lee, W.Y.2
Wang, H.L.3
Sine, S.M.4
-
36
-
-
0036813523
-
Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors
-
12351715 1:CAS:528:DC%2BD38Xns1Cju74%3D
-
Scheller M, Forman SA (2002) Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors. J Neurosci 22:8411-8421
-
(2002)
J Neurosci
, vol.22
, pp. 8411-8421
-
-
Scheller, M.1
Forman, S.A.2
-
37
-
-
0032945358
-
GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts
-
9831714 10.1111/j.1469-7793.1999.027af.x 1:CAS:528:DyaK1MXhsFWisro%3D
-
Haas KF, Macdonald RL (1999) GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. J Physiol 514(Pt 1):27-45
-
(1999)
J Physiol
, vol.514
, Issue.PART 1
, pp. 27-45
-
-
Haas, K.F.1
MacDonald, R.L.2
-
38
-
-
0034143449
-
Effects of halothane on GABA(A) receptor kinetics: Evidence for slowed agonist unbinding
-
10648694 1:CAS:528:DC%2BD3cXhtFGqt70%3D
-
Li X, Pearce RA (2000) Effects of halothane on GABA(A) receptor kinetics: evidence for slowed agonist unbinding. J Neurosci 20:899-907
-
(2000)
J Neurosci
, vol.20
, pp. 899-907
-
-
Li, X.1
Pearce, R.A.2
-
39
-
-
0034740987
-
Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states
-
11640928 10.1016/S0028-3908(01)00132-0 1:CAS:528:DC%2BD3MXnsFyqu7s%3D
-
Bianchi MT, Macdonald RL (2001) Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states. Neuropharmacology 41:737-744
-
(2001)
Neuropharmacology
, vol.41
, pp. 737-744
-
-
Bianchi, M.T.1
MacDonald, R.L.2
-
40
-
-
50349093448
-
The interface between extracellular and transmembrane domains of homomeric cys-loop receptors governs open-channel lifetime and rate of desensitization
-
18667613 10.1523/JNEUROSCI.0448-08.2008 1:CAS:528:DC%2BD1cXpsFOks74%3D
-
Bouzat C, Bartos M, Corradi J, Sine SM (2008) The interface between extracellular and transmembrane domains of homomeric cys-loop receptors governs open-channel lifetime and rate of desensitization. J Neurosci 28:7808-7819
-
(2008)
J Neurosci
, vol.28
, pp. 7808-7819
-
-
Bouzat, C.1
Bartos, M.2
Corradi, J.3
Sine, S.M.4
-
41
-
-
36849075297
-
Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: Interpretation within an allosteric kinetic model
-
18045909 10.1523/JNEUROSCI.3772-07.2007 1:CAS:528:DC%2BD2sXhsVeku7jF
-
Solt K, Ruesch D, Forman SA, Davies PA, Raines DE (2007) Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: interpretation within an allosteric kinetic model. J Neurosci 27:13151-13160
-
(2007)
J Neurosci
, vol.27
, pp. 13151-13160
-
-
Solt, K.1
Ruesch, D.2
Forman, S.A.3
Davies, P.A.4
Raines, D.E.5
-
42
-
-
77952908488
-
Desensitization and models of receptor-channel activation
-
20436045 10.1113/jphysiol.2010.188664 1:CAS:528:DC%2BC3cXmtlWiurc%3D
-
Shelley C, Cull-Candy SG (2010) Desensitization and models of receptor-channel activation. J Physiol 588:1395-1397
-
(2010)
J Physiol
, vol.588
, pp. 1395-1397
-
-
Shelley, C.1
Cull-Candy, S.G.2
-
43
-
-
0024312649
-
Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp
-
2561785 1:CAS:528:DyaL1MXksFSqt74%3D
-
Cachelin AB, Colquhoun D (1989) Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. J Physiol 415:159-188
-
(1989)
J Physiol
, vol.415
, pp. 159-188
-
-
Cachelin, A.B.1
Colquhoun, D.2
-
44
-
-
0027509690
-
A molecular scheme for the reaction between acetylcholine and nicotinic channels
-
7681332 10.1016/S0006-3495(93)81374-2 1:CAS:528:DyaK3sXhvVCis70%3D
-
Franke C, Parnas H, Hovav G, Dudel J (1993) A molecular scheme for the reaction between acetylcholine and nicotinic channels. Biophys J 64:339-356
-
(1993)
Biophys J
, vol.64
, pp. 339-356
-
-
Franke, C.1
Parnas, H.2
Hovav, G.3
Dudel, J.4
-
45
-
-
0037107163
-
Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function
-
12223551 1:CAS:528:DC%2BD38Xnt12ksLs%3D
-
Chang Y, Ghansah E, Chen Y, Ye J, Weiss DS (2002) Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function. J Neurosci 22:7982-7990
-
(2002)
J Neurosci
, vol.22
, pp. 7982-7990
-
-
Chang, Y.1
Ghansah, E.2
Chen, Y.3
Ye, J.4
Weiss, D.S.5
-
46
-
-
0038149197
-
Life at the top: The transition state of AChR gating
-
12824477 10.1126/stke.2003.188.re11
-
Auerbach A (2003) Life at the top: the transition state of AChR gating. Sci STKE 2003(188):re11
-
(2003)
Sci STKE
, vol.2003
, Issue.188
, pp. 11
-
-
Auerbach, A.1
-
47
-
-
41649119572
-
Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
-
18376414 10.1038/nsmb.1407 1:CAS:528:DC%2BD1cXktFyjtb8%3D
-
Cymes GD, Grosman C (2008) Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer. Nat Struct Mol Biol 15:389-396
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 389-396
-
-
Cymes, G.D.1
Grosman, C.2
-
48
-
-
65949085351
-
Number and locations of agonist binding sites required to activate homomeric cys-loop receptors
-
19420269 10.1523/JNEUROSCI.0627-09.2009 1:CAS:528:DC%2BD1MXlvVGntL4%3D
-
Rayes D, De Rosa MJ, Sine SM, Bouzat C (2009) Number and locations of agonist binding sites required to activate homomeric cys-loop receptors. J Neurosci 29:6022-6032
-
(2009)
J Neurosci
, vol.29
, pp. 6022-6032
-
-
Rayes, D.1
De Rosa, M.J.2
Sine, S.M.3
Bouzat, C.4
-
49
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
15701510 10.1016/j.jmb.2004.12.031 1:CAS:528:DC%2BD2MXhtFGrsbs%3D
-
Unwin N (2005) Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol 346:967-989
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
50
-
-
0037448581
-
Coupling of agonist binding to channel gating in the GABA(A) receptor
-
12529644 10.1038/nature01280 1:CAS:528:DC%2BD3sXjsF2htA%3D%3D
-
Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL (2003) Coupling of agonist binding to channel gating in the GABA(A) receptor. Nature 421:272-275
-
(2003)
Nature
, vol.421
, pp. 272-275
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
51
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
15318223 10.1038/nature02753 1:CAS:528:DC%2BD2cXmslCnuro%3D
-
Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, Taylor P, Sine SM (2004) Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature 430:896-900
-
(2004)
Nature
, vol.430
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
Taylor, P.7
Sine, S.M.8
-
52
-
-
1842686239
-
Gating dynamics of the acetylcholine receptor extracellular domain
-
15051806 10.1085/jgp.200309004 1:CAS:528:DC%2BD2cXjs1aitLY%3D
-
Chakrapani S, Bailey TD, Auerbach A (2004) Gating dynamics of the acetylcholine receptor extracellular domain. J Gen Physiol 123:341-356
-
(2004)
J Gen Physiol
, vol.123
, pp. 341-356
-
-
Chakrapani, S.1
Bailey, T.D.2
Auerbach, A.3
-
53
-
-
27744438169
-
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
-
16281039 10.1038/nature04156 1:CAS:528:DC%2BD2MXhtF2nsrjE
-
Lee WY, Sine SM (2005) Principal pathway coupling agonist binding to channel gating in nicotinic receptors. Nature 438:243-247
-
(2005)
Nature
, vol.438
, pp. 243-247
-
-
Lee, W.Y.1
Sine, S.M.2
-
54
-
-
27744608733
-
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
-
16281040 10.1038/nature04130 1:CAS:528:DC%2BD2MXhtF2nsrjL
-
Lummis SC, Beene DL, Lee LW, Lester HA, Broadhurst RW, Dougherty DA (2005) Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. Nature 438:248-252
-
(2005)
Nature
, vol.438
, pp. 248-252
-
-
Lummis, S.C.1
Beene, D.L.2
Lee, L.W.3
Lester, H.A.4
Broadhurst, R.W.5
Dougherty, D.A.6
-
55
-
-
29344468233
-
Improved gating of a chimeric alpha7-5HT3A receptor upon mutations at the M2-M3 extracellular loop
-
16364316 10.1016/j.febslet.2005.12.010 1:CAS:528:DC%2BD28Xkslyn
-
Castillo M, Mulet J, Bernal JA, Criado M, Sala F, Sala S (2006) Improved gating of a chimeric alpha7-5HT3A receptor upon mutations at the M2-M3 extracellular loop. FEBS Lett 580:256-260
-
(2006)
FEBS Lett
, vol.580
, pp. 256-260
-
-
Castillo, M.1
Mulet, J.2
Bernal, J.A.3
Criado, M.4
Sala, F.5
Sala, S.6
-
56
-
-
33644520967
-
Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation
-
16481436 10.1523/JNEUROSCI.4555-05.2006 1:CAS:528:DC%2BD28XitVansLc%3D
-
Mercado J, Czajkowski C (2006) Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation. J Neurosci 26:2031-2040
-
(2006)
J Neurosci
, vol.26
, pp. 2031-2040
-
-
Mercado, J.1
Czajkowski, C.2
-
57
-
-
0031027684
-
Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel
-
9009272 10.1093/emboj/16.1.110 1:CAS:528:DyaK2sXot1GmtQ%3D%3D
-
Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH, Schofield PR (1997) Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. EMBO J 16:110-120
-
(1997)
EMBO J
, vol.16
, pp. 110-120
-
-
Lynch, J.W.1
Rajendra, S.2
Pierce, K.D.3
Handford, C.A.4
Barry, P.H.5
Schofield, P.R.6
-
58
-
-
0032520102
-
Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes
-
9490812 10.1111/j.1469-7793.1998.025bu.x 1:CAS:528:DyaK1cXhslyjsb0%3D
-
Lewis TM, Sivilotti LG, Colquhoun D, Gardiner RM, Schoepfer R, Rees M (1998) Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. J Physiol 507(Pt 1):25-40
-
(1998)
J Physiol
, vol.507
, Issue.PART 1
, pp. 25-40
-
-
Lewis, T.M.1
Sivilotti, L.G.2
Colquhoun, D.3
Gardiner, R.M.4
Schoepfer, R.5
Rees, M.6
-
59
-
-
0010214174
-
Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor
-
6320162 10.1073/pnas.81.1.155 1:CAS:528:DyaL2cXotVSjuw%3D%3D
-
Finer-Moore J, Stroud RM (1984) Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor. Proc Natl Acad Sci U S A 81:155-159
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 155-159
-
-
Finer-Moore, J.1
Stroud, R.M.2
-
60
-
-
77949521932
-
Advances and hold-ups in the study of structure, function and regulation of cys-loop ligand-gated ion channels and receptors
-
20173078 10.1113/jphysiol.2009.185488 1:CAS:528:DC%2BC3cXisVeksL8%3D
-
Yakel J (2010) Advances and hold-ups in the study of structure, function and regulation of cys-loop ligand-gated ion channels and receptors. J Physiol 588:555-556
-
(2010)
J Physiol
, vol.588
, pp. 555-556
-
-
Yakel, J.1
-
61
-
-
77949521702
-
Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors
-
19933751 10.1113/jphysiol.2009.183137 1:CAS:528:DC%2BC3cXisVeksLs%3D
-
Peters JA, Cooper MA, Carland JE, Livesey MR, Hales TG, Lambert JJ (2010) Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors. J Physiol 588:587-596
-
(2010)
J Physiol
, vol.588
, pp. 587-596
-
-
Peters, J.A.1
Cooper, M.A.2
Carland, J.E.3
Livesey, M.R.4
Hales, T.G.5
Lambert, J.J.6
-
62
-
-
41649109805
-
Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
-
18204482 10.1038/sj.bjp.0707676 1:CAS:528:DC%2BD1cXktVWmsrs%3D
-
Kracun S, Harkness PC, Gibb AJ, Millar NS (2008) Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function. Br J Pharmacol 153:1474-1484
-
(2008)
Br J Pharmacol
, vol.153
, pp. 1474-1484
-
-
Kracun, S.1
Harkness, P.C.2
Gibb, A.J.3
Millar, N.S.4
-
63
-
-
0041806486
-
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
-
12867984 10.1038/nature01788 1:CAS:528:DC%2BD3sXlsVGjs7k%3D
-
Kelley SP, Dunlop JI, Kirkness EF, Lambert JJ, Peters JA (2003) A cytoplasmic region determines single-channel conductance in 5-HT3 receptors. Nature 424:321-324
-
(2003)
Nature
, vol.424
, pp. 321-324
-
-
Kelley, S.P.1
Dunlop, J.I.2
Kirkness, E.F.3
Lambert, J.J.4
Peters, J.A.5
-
64
-
-
26844573941
-
A role for the 1-2 loop in the gating of 5-HT3 receptors
-
16221844 10.1523/JNEUROSCI.1045-05.2005 1:CAS:528:DC%2BD2MXhtFGmu7rI
-
Reeves DC (2005) A role for the 1-2 loop in the gating of 5-HT3 receptors. J Neurosci 25:9358-9366
-
(2005)
J Neurosci
, vol.25
, pp. 9358-9366
-
-
Reeves, D.C.1
-
65
-
-
38749094806
-
Modular design of cys-loop ligand-gated ion channels: Functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop
-
18227272 10.1085/jgp.200709896 1:CAS:528:DC%2BD1cXis1WktLY%3D
-
Jansen M, Bali M, Akabas MH (2008) Modular design of cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop. J Gen Physiol 131:137-146
-
(2008)
J Gen Physiol
, vol.131
, pp. 137-146
-
-
Jansen, M.1
Bali, M.2
Akabas, M.H.3
-
66
-
-
50349086199
-
2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor
-
18474595 10.1074/jbc.M802406200 1:CAS:528:DC%2BD1cXotF2ks70%3D
-
2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. J Biol Chem 283:19301-19313
-
(2008)
J Biol Chem
, vol.283
, pp. 19301-19313
-
-
Livesey, M.R.1
Cooper, M.A.2
Deeb, T.Z.3
Carland, J.E.4
Kozuska, J.5
Hales, T.G.6
Lambert, J.J.7
Peters, J.A.8
-
67
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
11836518 10.1038/nrn731 1:CAS:528:DC%2BD38Xhslyju7Y%3D
-
Karlin A (2002) Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci 3:102-114
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
68
-
-
33744477329
-
Block of muscle nicotinic receptors by choline suggests that the activation and desensitization gates act as distinct molecular entities
-
16735755 10.1085/jgp.200509437 1:CAS:528:DC%2BD28Xms1SitLw%3D
-
Purohit Y, Grosman C (2006) Block of muscle nicotinic receptors by choline suggests that the activation and desensitization gates act as distinct molecular entities. J Gen Physiol 127:703-717
-
(2006)
J Gen Physiol
, vol.127
, pp. 703-717
-
-
Purohit, Y.1
Grosman, C.2
-
69
-
-
33644870155
-
Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP
-
16505382 10.1073/pnas.0507889103 1:CAS:528:DC%2BD28XivFWju74%3D
-
Ulens C, Hogg RC, Celie PH, Bertrand D, Tsetlin V, Smit AB, Sixma TK (2006) Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proc Natl Acad Sci U S A 103:3615-3620
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3615-3620
-
-
Ulens, C.1
Hogg, R.C.2
Celie, P.H.3
Bertrand, D.4
Tsetlin, V.5
Smit, A.B.6
Sixma, T.K.7
-
70
-
-
0026079817
-
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
-
1719423 10.1038/353846a0 1:CAS:528:DyaK38XjvFKk
-
Revah F, Bertrand D, Galzi JL, Devillers-Thiery A, Mulle C, Hussy N, Bertrand S, Ballivet M, Changeux JP (1991) Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature 353:846-849
-
(1991)
Nature
, vol.353
, pp. 846-849
-
-
Revah, F.1
Bertrand, D.2
Galzi, J.L.3
Devillers-Thiery, A.4
Mulle, C.5
Hussy, N.6
Bertrand, S.7
Ballivet, M.8
Changeux, J.P.9
-
71
-
-
0027194134
-
Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes
-
8506347 10.1073/pnas.90.11.5030 1:CAS:528:DyaK2cXjtFKjsL4%3D
-
Yakel JL, Lagrutta A, Adelman JP, North RA (1993) Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes. Proc Natl Acad Sci U S A 90:5030-5033
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5030-5033
-
-
Yakel, J.L.1
Lagrutta, A.2
Adelman, J.P.3
North, R.A.4
-
72
-
-
0031967525
-
Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors
-
9495819 1:CAS:528:DyaK1cXhslCnu7o%3D
-
Chang Y, Weiss DS (1998) Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors. Mol Pharmacol 53:511-523
-
(1998)
Mol Pharmacol
, vol.53
, pp. 511-523
-
-
Chang, Y.1
Weiss, D.S.2
-
73
-
-
0033359997
-
Channel opening locks agonist onto the GABAC receptor
-
10195213 10.1038/6313 1:CAS:528:DyaK1MXhsl2gurc%3D
-
Chang Y, Weiss DS (1999) Channel opening locks agonist onto the GABAC receptor. Nat Neurosci 2:219-225
-
(1999)
Nat Neurosci
, vol.2
, pp. 219-225
-
-
Chang, Y.1
Weiss, D.S.2
-
74
-
-
0032728861
-
Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine
-
10545355 10.1016/S0006-3495(99)77089-X 1:CAS:528:DyaK1MXnt1Wktb8%3D
-
Chang Y, Weiss DS (1999) Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine. Biophys J 77:2542-2551
-
(1999)
Biophys J
, vol.77
, pp. 2542-2551
-
-
Chang, Y.1
Weiss, D.S.2
-
75
-
-
29244442919
-
A unified view of the role of electrostatic interactions in modulating the gating of cys loop receptors
-
16216879 10.1074/jbc.M508635200 1:CAS:528:DC%2BD2MXhtlShsbnO
-
Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA (2005) A unified view of the role of electrostatic interactions in modulating the gating of cys loop receptors. J Biol Chem 280:41655-41666
-
(2005)
J Biol Chem
, vol.280
, pp. 41655-41666
-
-
Xiu, X.1
Hanek, A.P.2
Wang, J.3
Lester, H.A.4
Dougherty, D.A.5
-
76
-
-
14844295746
-
Charged amino acids of the N-terminal domain are involved in coupling binding and gating in alpha7 nicotinic receptors
-
15611071 10.1074/jbc.M411048200 1:CAS:528:DC%2BD2MXhsV2qsbs%3D
-
Sala F, Mulet J, Sala S, Gerber S, Criado M (2005) Charged amino acids of the N-terminal domain are involved in coupling binding and gating in alpha7 nicotinic receptors. J Biol Chem 280:6642-6647
-
(2005)
J Biol Chem
, vol.280
, pp. 6642-6647
-
-
Sala, F.1
Mulet, J.2
Sala, S.3
Gerber, S.4
Criado, M.5
-
77
-
-
0037124034
-
Point mutation in the first transmembrane region of the beta 2 subunit of the gamma-aminobutyric acid type A receptor alters desensitization kinetics of gamma-aminobutyric acid- and anesthetic-induced channel gating
-
11877425 10.1074/jbc.M111215200 1:CAS:528:DC%2BD38XktVCgtrY%3D
-
Engblom AC, Carlson BX, Olsen RW, Schousboe A, Kristiansen U (2002) Point mutation in the first transmembrane region of the beta 2 subunit of the gamma-aminobutyric acid type A receptor alters desensitization kinetics of gamma-aminobutyric acid- and anesthetic-induced channel gating. J Biol Chem 277:17438-17447
-
(2002)
J Biol Chem
, vol.277
, pp. 17438-17447
-
-
Engblom, A.C.1
Carlson, B.X.2
Olsen, R.W.3
Schousboe, A.4
Kristiansen, U.5
-
78
-
-
0035866070
-
Structural determinants of fast desensitization and desensitization- deactivation coupling in GABAa receptors
-
11160383 1:CAS:528:DC%2BD3MXhtFers7o%3D
-
Bianchi MT, Haas KF, Macdonald RL (2001) Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors. J Neurosci 21:1127-1136
-
(2001)
J Neurosci
, vol.21
, pp. 1127-1136
-
-
Bianchi, M.T.1
Haas, K.F.2
MacDonald, R.L.3
-
79
-
-
0032527959
-
Separate domains for desensitization of GABA rho 1 and beta 2 subunits expressed in Xenopus oocytes
-
9662556 10.1007/s002329900398 1:CAS:528:DyaK1cXks1KltLY%3D
-
Lu L, Huang Y (1998) Separate domains for desensitization of GABA rho 1 and beta 2 subunits expressed in Xenopus oocytes. J Membr Biol 164:115-124
-
(1998)
J Membr Biol
, vol.164
, pp. 115-124
-
-
Lu, L.1
Huang, Y.2
-
80
-
-
78449248065
-
Rapid desensitization of the rat alpha7 nAChR is facilitated by the presence of a proline residue in the outer beta-sheet
-
20837638 10.1113/jphysiol.2010.195495 1:CAS:528:DC%2BC3cXhsFaqs7rF
-
McCormack TJ, Melis C, Colon J, Gay EA, Mike A, Karoly R, Lamb PW, Molteni C, Yakel JL (2010) Rapid desensitization of the rat alpha7 nAChR is facilitated by the presence of a proline residue in the outer beta-sheet. J Physiol 588:4415-4429
-
(2010)
J Physiol
, vol.588
, pp. 4415-4429
-
-
McCormack, T.J.1
Melis, C.2
Colon, J.3
Gay, E.A.4
Mike, A.5
Karoly, R.6
Lamb, P.W.7
Molteni, C.8
Yakel, J.L.9
-
81
-
-
77949509797
-
Gating of nicotinic ACh receptors: Latest insights into ligand binding and function
-
19917567 10.1113/jphysiol.2009.182691 1:CAS:528:DC%2BC3cXisVeksLg%3D
-
Yakel JL (2010) Gating of nicotinic ACh receptors: latest insights into ligand binding and function. J Physiol 588:597-602
-
(2010)
J Physiol
, vol.588
, pp. 597-602
-
-
Yakel, J.L.1
-
82
-
-
0035916261
-
Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit
-
11329274 10.1021/bi0020022 1:CAS:528:DC%2BD3MXlsFGitg%3D%3D
-
Bohler S, Gay S, Bertrand S, Corringer PJ, Edelstein SJ, Changeux JP, Bertrand D (2001) Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit. Biochemistry 40:2066-2074
-
(2001)
Biochemistry
, vol.40
, pp. 2066-2074
-
-
Bohler, S.1
Gay, S.2
Bertrand, S.3
Corringer, P.J.4
Edelstein, S.J.5
Changeux, J.P.6
Bertrand, D.7
-
83
-
-
4644265039
-
Molecular structure and function of the glycine receptor chloride channel
-
15383648 10.1152/physrev.00042.2003 1:CAS:528:DC%2BD2cXovVyltLk%3D
-
Lynch JW (2004) Molecular structure and function of the glycine receptor chloride channel. Physiol Rev 84:1051-1095
-
(2004)
Physiol Rev
, vol.84
, pp. 1051-1095
-
-
Lynch, J.W.1
-
84
-
-
0033080914
-
Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating
-
9920650 1:CAS:528:DyaK1MXpsl2mtQ%3D%3D
-
Saul B, Kuner T, Sobetzko D, Brune W, Hanefeld F, Meinck HM, Becker CM (1999) Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating. J Neurosci 19:869-877
-
(1999)
J Neurosci
, vol.19
, pp. 869-877
-
-
Saul, B.1
Kuner, T.2
Sobetzko, D.3
Brune, W.4
Hanefeld, F.5
Meinck, H.M.6
Becker, C.M.7
-
85
-
-
0035839433
-
Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization
-
11395484 10.1074/jbc.M100446200 1:CAS:528:DC%2BD3MXmtFeitbg%3D
-
Breitinger HG, Villmann C, Becker K, Becker CM (2001) Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization. J Biol Chem 276:29657-29663
-
(2001)
J Biol Chem
, vol.276
, pp. 29657-29663
-
-
Breitinger, H.G.1
Villmann, C.2
Becker, K.3
Becker, C.M.4
-
86
-
-
33746788525
-
An interaction involving an arginine residue in the cytoplasmic domain of the 5-HT3A receptor contributes to receptor desensitization mechanism
-
16754678 10.1074/jbc.M600676200 1:CAS:528:DC%2BD28XnsVOntbY%3D
-
Hu XQ, Sun H, Peoples RW, Hong R, Zhang L (2006) An interaction involving an arginine residue in the cytoplasmic domain of the 5-HT3A receptor contributes to receptor desensitization mechanism. J Biol Chem 281:21781-21788
-
(2006)
J Biol Chem
, vol.281
, pp. 21781-21788
-
-
Hu, X.Q.1
Sun, H.2
Peoples, R.W.3
Hong, R.4
Zhang, L.5
-
87
-
-
33344468020
-
Ligand binding transmits conformational changes across the membrane-spanning region to the intracellular side of the 5-HT3 serotonin receptor
-
16254942 10.1002/cbic.200500191 1:CAS:528:DC%2BD2MXhtlalu7fP
-
Ilegems E, Pick H, Deluz C, Kellenberger S, Vogel H (2005) Ligand binding transmits conformational changes across the membrane-spanning region to the intracellular side of the 5-HT3 serotonin receptor. ChemBioChem 6:2180-2185
-
(2005)
ChemBioChem
, vol.6
, pp. 2180-2185
-
-
Ilegems, E.1
Pick, H.2
Deluz, C.3
Kellenberger, S.4
Vogel, H.5
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