Coupling of agonist binding to channel gating in the GABAA receptor

Nature

Volumn 421, Issue 6920, 2003, Pages 272-275

  Kash, Thomas L ^a   Jenkins, Andrew ^b   Kelley, Jill C ^b   Trudell, James R ^c   Harrison, Neil L ^b  

^a Weill Cornell Medical Center   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSTATICS; GENES; MEMBRANES; PROTEINS;

NEUTROTRANSMITTERS;

NEUROLOGY;

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ACETYLCHOLINE; AMINO ACID; ASPARAGINE; BINDING PROTEIN; COMPLEMENTARY DNA; ION CHANNEL; LYSINE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

BIOLOGY;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHANNEL GATING; EMBRYO; EPILEPSY; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; MYASTHENIA; NEUROTRANSMISSION; PATCH CLAMP; POINT MUTATION; PRIORITY JOURNAL;

BINDING SITES; CELL LINE; CYSTEINE; DISULFIDES; ELECTROPHYSIOLOGY; ELECTROSTATICS; HUMANS; HYDROPHOBICITY; ION CHANNEL GATING; LIGANDS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; RECEPTORS, GABA-A;

EID: 0037448581     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01280     Document Type: Article

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