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Volumn 22, Issue 18, 2002, Pages 7982-7990

Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function

Author keywords

Affinity; Binding; Desensitization; GABAA receptor; Kinetics; Oocyte

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ION CHANNEL; LIGAND; TRITIUM;

EID: 0037107163     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-18-07982.2002     Document Type: Article
Times cited : (59)

References (26)
  • 1
    • 0027787023 scopus 로고
    • A receptor needs two homologous domains of the β-subunit for activation by GABA but not by pentobarbital
    • A receptor needs two homologous domains of the β-subunit for activation by GABA but not by pentobarbital. Nature 366:565-569.
    • (1993) Nature , vol.366 , pp. 565-569
    • Amin, J.1    Weiss, D.S.2
  • 2
    • 0028171915 scopus 로고
    • Homomeric ρ1 GABA channels: Activation properties and domains
    • Amin J, Weiss DS (1994) Homomeric ρ1 GABA channels: Activation properties and domains. Receptors Channels 2:227-236.
    • (1994) Receptors Channels , vol.2 , pp. 227-236
    • Amin, J.1    Weiss, D.S.2
  • 4
    • 0019225784 scopus 로고
    • 3H]acetylcholine to Torpedo postsynaptic membranes: Association and dissociation rate constants by rapid mixing and ultrafiltration
    • 3H]acetylcholine to Torpedo postsynaptic membranes: Association and dissociation rate constants by rapid mixing and ultrafiltration. Biochemistry 19:5353-5358.
    • (1980) Biochemistry , vol.19 , pp. 5353-5358
    • Boyd, N.D.1    Cohen, J.B.2
  • 6
    • 0032728861 scopus 로고    scopus 로고
    • A receptor revealed by mutation of the conserved M2 leucine
    • A receptor revealed by mutation of the conserved M2 leucine. Biophys J 77:2542-2551.
    • (1999) Biophys J , vol.77 , pp. 2542-2551
    • Chang, Y.1    Weiss, D.S.2
  • 7
    • 0032215090 scopus 로고    scopus 로고
    • Allosteric receptors after 30 years
    • Changeux J-P, Edelstein SJ (1998) Allosteric receptors after 30 years. Neuron 21:959-980.
    • (1998) Neuron , vol.21 , pp. 959-980
    • Changeux, J.-P.1    Edelstein, S.J.2
  • 8
    • 0032199006 scopus 로고    scopus 로고
    • Binding, gating, affinity, and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
    • Colquhoun D (1998) Binding, gating, affinity, and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125:923-948.
    • (1998) Br J Pharmacol , vol.125 , pp. 923-948
    • Colquhoun, D.1
  • 9
    • 0030481333 scopus 로고    scopus 로고
    • Allosteric proteins after thirty years: The binding and state functions of the neuronal α7 nicotinic acetylcholine receptors
    • Edelstein SJ, Changeux J-P (1996) Allosteric proteins after thirty years: The binding and state functions of the neuronal α7 nicotinic acetylcholine receptors. Experientia 52:1083-1090.
    • (1996) Experientia , vol.52 , pp. 1083-1090
    • Edelstein, S.J.1    Changeux, J.-P.2
  • 10
    • 0033563319 scopus 로고    scopus 로고
    • Upregulation of surface α4/β2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine
    • Fenster CP, Whitworth TL, Sheffield EB, Quick MW, Lester RAJ (1999) Upregulation of surface α4/β2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine. J Neurosci 19:4804-4814.
    • (1999) J Neurosci , vol.19 , pp. 4804-4814
    • Fenster, C.P.1    Whitworth, T.L.2    Sheffield, E.B.3    Quick, M.W.4    Lester, R.A.J.5
  • 11
    • 0021041862 scopus 로고
    • Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine rich membranes from Torpedo marmorata
    • Heidmann T, Bernhardt J, Neumann E, Changeux JP (1983) Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine rich membranes from Torpedo marmorata. Biochemistry 22:5452-5459.
    • (1983) Biochemistry , vol.22 , pp. 5452-5459
    • Heidmann, T.1    Bernhardt, J.2    Neumann, E.3    Changeux, J.P.4
  • 12
    • 0029112106 scopus 로고
    • A channel responses to brief agonist pulses
    • A channel responses to brief agonist pulses. Neuron 15:181-191.
    • (1995) Neuron , vol.15 , pp. 181-191
    • Jones, M.V.1    Westbrook, G.L.2
  • 13
    • 84965075853 scopus 로고
    • A study of the desensitization produced by acetylcholine at the motor end-plate
    • Katz B, Thesleff S (1957) A study of the desensitization produced by acetylcholine at the motor end-plate. J Phvsiol (Lond) 138:63-80.
    • (1957) J Phvsiol (Lond) , vol.138 , pp. 63-80
    • Katz, B.1    Thesleff, S.2
  • 14
    • 0026485457 scopus 로고
    • + channel determined by construction of multimeric cDNAs
    • + channel determined by construction of multimeric cDNAs. Neuron 9:861-871.
    • (1992) Neuron , vol.9 , pp. 861-871
    • Liman, E.R.1    Tytgat, J.2    Hess, P.3
  • 15
    • 0019985295 scopus 로고
    • Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization
    • Neubig RR, Boyd ND, Cohen JB (1982) Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization. Biochemistry 21:3460-3467.
    • (1982) Biochemistry , vol.21 , pp. 3460-3467
    • Neubig, R.R.1    Boyd, N.D.2    Cohen, J.B.3
  • 17
    • 0021181988 scopus 로고
    • Biochemical pharmacology of the γ-aminobutyric acid receptor/ionophore protein
    • Olsen RW, Wong EHF, Stauber GB, King RG (1984) Biochemical pharmacology of the γ-aminobutyric acid receptor/ionophore protein. Fed Proc 43:2773-2778.
    • (1984) Fed Proc , vol.43 , pp. 2773-2778
    • Olsen, R.W.1    Wong, E.H.F.2    Stauber, G.B.3    King, R.G.4
  • 19
    • 0017886343 scopus 로고
    • Ligand-induced conformation changes in Torpedo californica membrane-bound acetylcholine receptor
    • Quast U, Schimerlik M, Witzemann V, Blanchard S, Raftery MA (1978) Ligand-induced conformation changes in Torpedo californica membrane-bound acetylcholine receptor. Biochemistry 17:2405-2414.
    • (1978) Biochemistry , vol.17 , pp. 2405-2414
    • Quast, U.1    Schimerlik, M.2    Witzemann, V.3    Blanchard, S.4    Raftery, M.A.5
  • 20
    • 0014824340 scopus 로고
    • On the mechanism of desensitization at cholinergic receptors
    • Rang HP, Ritter JM (1970) On the mechanism of desensitization at cholinergic receptors. Mol Pharmacol 6:357-382.
    • (1970) Mol Pharmacol , vol.6 , pp. 357-382
    • Rang, H.P.1    Ritter, J.M.2
  • 21
    • 0018389601 scopus 로고
    • Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells
    • Sine SM, Taylor P (1979) Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells. J Biol Chem 254:3315-3325.
    • (1979) J Biol Chem , vol.254 , pp. 3315-3325
    • Sine, S.M.1    Taylor, P.2
  • 23
    • 0016760413 scopus 로고
    • Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata
    • Weber M, David-Pfeuty T, Changeux J (1975) Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata. Proc Natl Acad Sci USA 72:3443-3447.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 3443-3447
    • Weber, M.1    David-Pfeuty, T.2    Changeux, J.3
  • 24
    • 0017717088 scopus 로고
    • Kinetics of agonist-mediated transitions in state of the cholinergic receptor
    • Weiland G, Georgia B, Lappi S, Chignell C, Taylor P (1975) Kinetics of agonist-mediated transitions in state of the cholinergic receptor. J Biol Chem 252:7648-7656.
    • (1975) J Biol Chem , vol.252 , pp. 7648-7656
    • Weiland, G.1    Georgia, B.2    Lappi, S.3    Chignell, C.4    Taylor, P.5
  • 25
    • 0031156830 scopus 로고    scopus 로고
    • A channel deactivation by altering kinetics of desensitized states
    • A channel deactivation by altering kinetics of desensitized states. J Neurosci 17:4022-4031.
    • (1997) J Neurosci , vol.17 , pp. 4022-4031
    • Zhu, W.J.1    Vicini, S.2
  • 26
    • 0016362594 scopus 로고
    • Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system
    • Zukin SR, Young AB, Snyder SH (1974) Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system. Proc Natl Acad Sci USA 71:4802-4807.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 4802-4807
    • Zukin, S.R.1    Young, A.B.2    Snyder, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.