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Volumn 78, Issue 2, 2013, Pages 172-180

Holistic Systems Biology Approaches to Molecular Mechanisms of Human Helper T Cell Differentiation to Functionally Distinct Subsets

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DNA; FURIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C GAMMA1; SMALL INTERFERING RNA; STAT3 PROTEIN; STAT4 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; Y BOX BINDING PROTEIN 1;

EID: 84880652652     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12071     Document Type: Review
Times cited : (3)

References (100)
  • 1
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu J, Yamane H, Paul WE. Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol 2010;28:445-89.
    • (2010) Annu Rev Immunol , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 2
    • 79251578351 scopus 로고    scopus 로고
    • Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1. 1- invariant NKT cells to bacteria
    • Jan
    • Doisne JM, Soulard V, Bécourt C et al. Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1. 1- invariant NKT cells to bacteria. J Immunol 2011 Jan;186:662-6.
    • (2011) J Immunol , vol.186 , pp. 662-666
    • Doisne, J.M.1    Soulard, V.2    Bécourt, C.3
  • 3
    • 44849133287 scopus 로고    scopus 로고
    • The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function
    • Shevach EM, Tran DQ, Davidson TS, Andersson J. The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function. Eur J Immunol 2008;38:915-7.
    • (2008) Eur J Immunol , vol.38 , pp. 915-917
    • Shevach, E.M.1    Tran, D.Q.2    Davidson, T.S.3    Andersson, J.4
  • 4
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 5
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol 2002;2:933-44.
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 6
    • 0028201726 scopus 로고
    • Acquisition of lymphokine-producing phenotype by CD4+ T cells
    • Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994;12:635-73.
    • (1994) Annu Rev Immunol , vol.12 , pp. 635-673
    • Seder, R.A.1    Paul, W.E.2
  • 7
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995;270:467-70.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 8
    • 0031962882 scopus 로고    scopus 로고
    • DNA chips: an array of possibilities
    • Marshall A, Hodgson J. DNA chips: an array of possibilities. Nat Biotechnol 1998;16:27-31.
    • (1998) Nat Biotechnol , vol.16 , pp. 27-31
    • Marshall, A.1    Hodgson, J.2
  • 9
    • 0034075845 scopus 로고    scopus 로고
    • Transcript imaging of the development of human T helper cells using oligonucleotide arrays
    • Rogge L, Bianchi E, Biffi M et al. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nat Genet 2000;25:96-101.
    • (2000) Nat Genet , vol.25 , pp. 96-101
    • Rogge, L.1    Bianchi, E.2    Biffi, M.3
  • 11
    • 0242662850 scopus 로고    scopus 로고
    • Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes
    • Lund R, Aittokallio T, Nevalainen O, Lahesmaa R. Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes. J Immunol 2003;171:5328-36.
    • (2003) J Immunol , vol.171 , pp. 5328-5336
    • Lund, R.1    Aittokallio, T.2    Nevalainen, O.3    Lahesmaa, R.4
  • 12
    • 33947207887 scopus 로고    scopus 로고
    • Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation
    • Lund RJ, Löytömäki M, Naumanen T et al. Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation. J Immunol 2007;178:3648-60.
    • (2007) J Immunol , vol.178 , pp. 3648-3660
    • Lund, R.J.1    Löytömäki, M.2    Naumanen, T.3
  • 13
    • 0032534672 scopus 로고    scopus 로고
    • The role of Stat4 in species-specific regulation of Th cell development by type I IFNs
    • Rogge L, D'Ambrosio D, Biffi M et al. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J Immunol 1998;161:6567-74.
    • (1998) J Immunol , vol.161 , pp. 6567-6574
    • Rogge, L.1    D'Ambrosio, D.2    Biffi, M.3
  • 14
    • 77954465997 scopus 로고    scopus 로고
    • Activating transcription factor 3 is a positive regulator of human IFNG gene expression
    • Filén S, Ylikoski E, Tripathi S et al. Activating transcription factor 3 is a positive regulator of human IFNG gene expression. J Immunol 2010;184:4990-9.
    • (2010) J Immunol , vol.184 , pp. 4990-4999
    • Filén, S.1    Ylikoski, E.2    Tripathi, S.3
  • 15
    • 0035884779 scopus 로고    scopus 로고
    • Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells
    • Chtanova T, Kemp RA, Sutherland AP, Ronchese F, Mackay CR. Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells. J Immunol 2001;167:3057-63.
    • (2001) J Immunol , vol.167 , pp. 3057-3063
    • Chtanova, T.1    Kemp, R.A.2    Sutherland, A.P.3    Ronchese, F.4    Mackay, C.R.5
  • 16
    • 15844374279 scopus 로고    scopus 로고
    • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
    • Shimoda K, van Deursen J, Sangster MY et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996;380:630-3.
    • (1996) Nature , vol.380 , pp. 630-633
    • Shimoda, K.1    van Deursen, J.2    Sangster, M.Y.3
  • 17
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996;4:313-9.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 18
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996;382:174-7.
    • (1996) Nature , vol.382 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 19
    • 15844404509 scopus 로고    scopus 로고
    • Essential role of Stat6 in IL-4 signalling
    • Takeda K, Tanaka T, Shi W et al. Essential role of Stat6 in IL-4 signalling. Nature 1996;380:627-30.
    • (1996) Nature , vol.380 , pp. 627-630
    • Takeda, K.1    Tanaka, T.2    Shi, W.3
  • 20
    • 15844396183 scopus 로고    scopus 로고
    • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    • Thierfelder WE, van Deursen JM, Yamamoto K et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996;382:171-4.
    • (1996) Nature , vol.382 , pp. 171-174
    • Thierfelder, W.E.1    van Deursen, J.M.2    Yamamoto, K.3
  • 22
    • 2442711457 scopus 로고    scopus 로고
    • Early target genes of IL-12 and STAT4 signaling in Th cells
    • Lund RJ, Chen Z, Scheinin J, Lahesmaa R. Early target genes of IL-12 and STAT4 signaling in Th cells. J Immunol 2004;172:6775-82.
    • (2004) J Immunol , vol.172 , pp. 6775-6782
    • Lund, R.J.1    Chen, Z.2    Scheinin, J.3    Lahesmaa, R.4
  • 23
    • 51649112340 scopus 로고    scopus 로고
    • T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance
    • Pesu M, Watford WT, Wei L et al. T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance. Nature 2008;455:246-50.
    • (2008) Nature , vol.455 , pp. 246-250
    • Pesu, M.1    Watford, W.T.2    Wei, L.3
  • 24
    • 84862514267 scopus 로고    scopus 로고
    • Identification of early gene expression changes during human Th17 cell differentiation
    • Tuomela S, Salo V, Tripathi SK et al. Identification of early gene expression changes during human Th17 cell differentiation. Blood 2012;119:e151-60.
    • (2012) Blood , vol.119
    • Tuomela, S.1    Salo, V.2    Tripathi, S.K.3
  • 25
    • 70449571945 scopus 로고    scopus 로고
    • The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
    • Jenner RG, Townsend MJ, Jackson I et al. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci U S A 2009;106:17876-81.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 17876-17881
    • Jenner, R.G.1    Townsend, M.J.2    Jackson, I.3
  • 26
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
    • Xu L, Kitani A, Fuss I, Strober W. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol 2007;178:6725-9.
    • (2007) J Immunol , vol.178 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 28
    • 74549179138 scopus 로고    scopus 로고
    • Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
    • Hegazy AN, Peine M, Helmstetter C et al. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 2010;32:116-28.
    • (2010) Immunity , vol.32 , pp. 116-128
    • Hegazy, A.N.1    Peine, M.2    Helmstetter, C.3
  • 29
    • 84860241847 scopus 로고    scopus 로고
    • Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
    • Zielinski CE, Mele F, Aschenbrenner D et al. Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. Nature 2012;484:514-8.
    • (2012) Nature , vol.484 , pp. 514-518
    • Zielinski, C.E.1    Mele, F.2    Aschenbrenner, D.3
  • 30
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G, Wei L, Zhu J et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009;30:155-67.
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3
  • 31
    • 77953293952 scopus 로고    scopus 로고
    • Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis
    • Durant L, Watford WT, Ramos HL et al. Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. Immunity 2010;32:605-15.
    • (2010) Immunity , vol.32 , pp. 605-615
    • Durant, L.1    Watford, W.T.2    Ramos, H.L.3
  • 32
    • 77953917067 scopus 로고    scopus 로고
    • Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
    • Wei L, Vahedi G, Sun HW et al. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 2010;32:840-51.
    • (2010) Immunity , vol.32 , pp. 840-851
    • Wei, L.1    Vahedi, G.2    Sun, H.W.3
  • 33
    • 79951682333 scopus 로고    scopus 로고
    • Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
    • Yang XP, Ghoreschi K, Steward-Tharp SM et al. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat Immunol 2011;12:247-54.
    • (2011) Nat Immunol , vol.12 , pp. 247-254
    • Yang, X.P.1    Ghoreschi, K.2    Steward-Tharp, S.M.3
  • 34
    • 80051885764 scopus 로고    scopus 로고
    • Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
    • Wei G, Abraham BJ, Yagi R et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 2011;35:299-311.
    • (2011) Immunity , vol.35 , pp. 299-311
    • Wei, G.1    Abraham, B.J.2    Yagi, R.3
  • 35
    • 71749089605 scopus 로고    scopus 로고
    • Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors
    • Kwon H, Thierry-Mieg D, Thierry-Mieg J et al. Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity 2009;31:941-52.
    • (2009) Immunity , vol.31 , pp. 941-952
    • Kwon, H.1    Thierry-Mieg, D.2    Thierry-Mieg, J.3
  • 36
    • 79958042030 scopus 로고    scopus 로고
    • Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
    • Horiuchi S, Onodera A, Hosokawa H et al. Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3. J Immunol 2011;186:6378-89.
    • (2011) J Immunol , vol.186 , pp. 6378-6389
    • Horiuchi, S.1    Onodera, A.2    Hosokawa, H.3
  • 37
    • 54549103162 scopus 로고    scopus 로고
    • Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
    • Liao W, Schones DE, Oh J et al. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol 2008;9:1288-96.
    • (2008) Nat Immunol , vol.9 , pp. 1288-1296
    • Liao, W.1    Schones, D.E.2    Oh, J.3
  • 38
    • 77953881949 scopus 로고    scopus 로고
    • Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming
    • Elo LL, Järvenpää H, Tuomela S et al. Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming. Immunity 2010;32:852-62.
    • (2010) Immunity , vol.32 , pp. 852-862
    • Elo, L.L.1    Järvenpää, H.2    Tuomela, S.3
  • 39
    • 84871783406 scopus 로고    scopus 로고
    • T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
    • Kanhere A, Hertweck A, Bhatia U et al. T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun 2012;3:1268.
    • (2012) Nat Commun , vol.3 , pp. 1268
    • Kanhere, A.1    Hertweck, A.2    Bhatia, U.3
  • 40
    • 84870027825 scopus 로고    scopus 로고
    • STATs shape the active enhancer landscape of T cell populations
    • Vahedi G, Takahashi H, Nakayamada S et al. STATs shape the active enhancer landscape of T cell populations. Cell 2012;151:981-93.
    • (2012) Cell , vol.151 , pp. 981-993
    • Vahedi, G.1    Takahashi, H.2    Nakayamada, S.3
  • 41
    • 84879604583 scopus 로고    scopus 로고
    • Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization
    • doi.org/10.1016/j.immuni.2013.05.011.
    • Hawkins RD, Larjo A, Tripathi SK et al. Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization. Immunity 2013. doi.org/10.1016/j.immuni.2013.05.011.
    • (2013) Immunity
    • Hawkins, R.D.1    Larjo, A.2    Tripathi, S.K.3
  • 42
    • 77956534729 scopus 로고    scopus 로고
    • SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation
    • Ahlfors H, Limaye A, Elo LL et al. SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation. Blood 2010;116:1443-53.
    • (2010) Blood , vol.116 , pp. 1443-1453
    • Ahlfors, H.1    Limaye, A.2    Elo, L.L.3
  • 43
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • Cai S, Lee CC, Kohwi-Shigematsu T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet 2006;38:1278-88.
    • (2006) Nat Genet , vol.38 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 44
    • 80052023563 scopus 로고    scopus 로고
    • Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
    • Beyer M, Thabet Y, Müller RU et al. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 2011;12:898-907.
    • (2011) Nat Immunol , vol.12 , pp. 898-907
    • Beyer, M.1    Thabet, Y.2    Müller, R.U.3
  • 45
    • 0028868332 scopus 로고
    • Costimulatory signals can selectively modulate cytokine production by subsets of CD4+ T cells
    • Shanafelt MC, Soderberg C, Allsup A, Adelman D, Peltz G, Lahesmaa R. Costimulatory signals can selectively modulate cytokine production by subsets of CD4+ T cells. J Immunol 1995;154:1684-90.
    • (1995) J Immunol , vol.154 , pp. 1684-1690
    • Shanafelt, M.C.1    Soderberg, C.2    Allsup, A.3    Adelman, D.4    Peltz, G.5    Lahesmaa, R.6
  • 47
    • 84858439862 scopus 로고    scopus 로고
    • Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
    • Vogel C, Marcotte EM. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat Rev Genet 2012;13:227-32.
    • (2012) Nat Rev Genet , vol.13 , pp. 227-232
    • Vogel, C.1    Marcotte, E.M.2
  • 48
    • 13344269000 scopus 로고    scopus 로고
    • From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis
    • Wilkins MR, Pasquali C, Appel RD et al. From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis. Biotechnology (N Y) 1996;14:61-5.
    • (1996) Biotechnology (N Y) , vol.14 , pp. 61-65
    • Wilkins, M.R.1    Pasquali, C.2    Appel, R.D.3
  • 49
    • 77957220211 scopus 로고    scopus 로고
    • Two-dimensional gel electrophoresis in proteomics: past, present and future
    • Rabilloud T, Chevallet M, Luche S, Lelong C. Two-dimensional gel electrophoresis in proteomics: past, present and future. J Proteomics 2010;73:2064-77.
    • (2010) J Proteomics , vol.73 , pp. 2064-2077
    • Rabilloud, T.1    Chevallet, M.2    Luche, S.3    Lelong, C.4
  • 50
    • 0042386240 scopus 로고    scopus 로고
    • Protein identification: the origins of peptide mass fingerprinting
    • Henzel WJ, Watanabe C, Stults JT. Protein identification: the origins of peptide mass fingerprinting. J Am Soc Mass Spectrom 2003;14:931-42.
    • (2003) J Am Soc Mass Spectrom , vol.14 , pp. 931-942
    • Henzel, W.J.1    Watanabe, C.2    Stults, J.T.3
  • 51
    • 0033838452 scopus 로고    scopus 로고
    • A two dimensional electrophoresis database of a human Jurkat T-cell line
    • Thiede B, Siejak F, Dimmler C, Jungblut PR, Rudel T. A two dimensional electrophoresis database of a human Jurkat T-cell line. Electrophoresis 2000;21:2713-20.
    • (2000) Electrophoresis , vol.21 , pp. 2713-2720
    • Thiede, B.1    Siejak, F.2    Dimmler, C.3    Jungblut, P.R.4    Rudel, T.5
  • 53
    • 0033946833 scopus 로고    scopus 로고
    • Proteome analysis reveals ubiquitin-conjugating enzymes to be a new family of interferon-alpha-regulated genes
    • Nyman TA, Matikainen S, Sareneva T, Julkunen I, Kalkkinen N. Proteome analysis reveals ubiquitin-conjugating enzymes to be a new family of interferon-alpha-regulated genes. Eur J Biochem 2000;267:4011-9.
    • (2000) Eur J Biochem , vol.267 , pp. 4011-4019
    • Nyman, T.A.1    Matikainen, S.2    Sareneva, T.3    Julkunen, I.4    Kalkkinen, N.5
  • 54
    • 0942265391 scopus 로고    scopus 로고
    • Proteome characterization of human T helper 1 and 2 cells
    • Rautajoki K, Nyman TA, Lahesmaa R. Proteome characterization of human T helper 1 and 2 cells. Proteomics 2004;4:84-92.
    • (2004) Proteomics , vol.4 , pp. 84-92
    • Rautajoki, K.1    Nyman, T.A.2    Lahesmaa, R.3
  • 55
    • 33847611217 scopus 로고    scopus 로고
    • Interleukin-4 inhibits caspase-3 by regulating several proteins in the Fas pathway during initial stages of human T helper 2 cell differentiation
    • Rautajoki KJ, Marttila EM, Nyman TA, Lahesmaa R. Interleukin-4 inhibits caspase-3 by regulating several proteins in the Fas pathway during initial stages of human T helper 2 cell differentiation. Mol Cell Proteomics 2007;6:238-51.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 238-251
    • Rautajoki, K.J.1    Marttila, E.M.2    Nyman, T.A.3    Lahesmaa, R.4
  • 56
    • 23844533258 scopus 로고    scopus 로고
    • Proteome profiling of interleukin-12 treated human T helper cells
    • Rosengren AT, Nyman TA, Lahesmaa R. Proteome profiling of interleukin-12 treated human T helper cells. Proteomics 2005;5:3137-41.
    • (2005) Proteomics , vol.5 , pp. 3137-3141
    • Rosengren, A.T.1    Nyman, T.A.2    Lahesmaa, R.3
  • 58
    • 0034659815 scopus 로고    scopus 로고
    • Proteomics to study genes and genomes
    • Pandey A, Mann M. Proteomics to study genes and genomes. Nature 2000;405:837-46.
    • (2000) Nature , vol.405 , pp. 837-846
    • Pandey, A.1    Mann, M.2
  • 59
    • 0034066471 scopus 로고    scopus 로고
    • Membrane proteins and proteomics: un amour impossible?
    • Santoni V, Molloy M, Rabilloud T. Membrane proteins and proteomics: un amour impossible? Electrophoresis 2000;21:1054-70.
    • (2000) Electrophoresis , vol.21 , pp. 1054-1070
    • Santoni, V.1    Molloy, M.2    Rabilloud, T.3
  • 60
    • 17444387111 scopus 로고    scopus 로고
    • Proteomic profiling of surface proteins on Th1 and Th2 cells
    • Loyet KM, Ouyang W, Eaton DL, Stults JT. Proteomic profiling of surface proteins on Th1 and Th2 cells. J Proteome Res 2005;4:400-9.
    • (2005) J Proteome Res , vol.4 , pp. 400-409
    • Loyet, K.M.1    Ouyang, W.2    Eaton, D.L.3    Stults, J.T.4
  • 61
    • 0347298692 scopus 로고    scopus 로고
    • Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering
    • Bini L, Pacini S, Liberatori S et al. Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering. Biochem J 2003;369:301-9.
    • (2003) Biochem J , vol.369 , pp. 301-309
    • Bini, L.1    Pacini, S.2    Liberatori, S.3
  • 62
    • 33746432742 scopus 로고    scopus 로고
    • The application of new software tools to quantitative protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry: I. Statistically annotated datasets for peptide sequences and proteins identified via the application of ICAT and tandem mass spectrometry to proteins copurifying with T cell lipid rafts
    • von Haller PD, Yi E, Donohoe S et al. The application of new software tools to quantitative protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry: I. Statistically annotated datasets for peptide sequences and proteins identified via the application of ICAT and tandem mass spectrometry to proteins copurifying with T cell lipid rafts. Mol Cell Proteomics 2003;2:426-7.
    • (2003) Mol Cell Proteomics , vol.2 , pp. 426-427
    • von Haller, P.D.1    Yi, E.2    Donohoe, S.3
  • 63
    • 34447259118 scopus 로고    scopus 로고
    • Global analysis of dynamic changes in lipid raft proteins during T-cell activation
    • Kobayashi M, Katagiri T, Kosako H, Iida N, Hattori S. Global analysis of dynamic changes in lipid raft proteins during T-cell activation. Electrophoresis 2007;28:2035-43.
    • (2007) Electrophoresis , vol.28 , pp. 2035-2043
    • Kobayashi, M.1    Katagiri, T.2    Kosako, H.3    Iida, N.4    Hattori, S.5
  • 64
    • 79953010049 scopus 로고    scopus 로고
    • Proteomic characterization of plasma membrane-proximal T cell activation responses
    • de Wet B, Zech T, Salek M, Acuto O, Harder T. Proteomic characterization of plasma membrane-proximal T cell activation responses. J Biol Chem 2011;286:4072-80.
    • (2011) J Biol Chem , vol.286 , pp. 4072-4080
    • de Wet, B.1    Zech, T.2    Salek, M.3    Acuto, O.4    Harder, T.5
  • 66
    • 14944354263 scopus 로고    scopus 로고
    • A systematic characterization of mitochondrial proteome from human T leukemia cells
    • Rezaul K, Wu L, Mayya V, Hwang S-I, Han D. A systematic characterization of mitochondrial proteome from human T leukemia cells. Mol Cell Proteomics 2005;4:169-81.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 169-181
    • Rezaul, K.1    Wu, L.2    Mayya, V.3    Hwang, S.-I.4    Han, D.5
  • 67
    • 29544450879 scopus 로고    scopus 로고
    • Characterization of microsomal fraction proteome in human lymphoblasts reveals the down-regulation of galectin-1 by interleukin-12
    • Filen JJ, Nyman TA, Korhonen J, Goodlett DR, Lahesmaa R. Characterization of microsomal fraction proteome in human lymphoblasts reveals the down-regulation of galectin-1 by interleukin-12. Proteomics 2005;5:4719-32.
    • (2005) Proteomics , vol.5 , pp. 4719-4732
    • Filen, J.J.1    Nyman, T.A.2    Korhonen, J.3    Goodlett, D.R.4    Lahesmaa, R.5
  • 68
    • 59149100864 scopus 로고    scopus 로고
    • Quantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiation
    • Filén J-J, Filén S, Moulder R et al. Quantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiation. Mol Cell Proteomics 2009;8:32-44.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 32-44
    • Filén, J.-J.1    Filén, S.2    Moulder, R.3
  • 69
    • 33745608428 scopus 로고    scopus 로고
    • Systematic characterization of nuclear proteome during apoptosis: a quantitative proteomic study by differential extraction and stable isotope labeling
    • Hwang S-I, Lundgren DH, Mayya V et al. Systematic characterization of nuclear proteome during apoptosis: a quantitative proteomic study by differential extraction and stable isotope labeling. Mol Cell Proteomics 2006;5:1131-45.
    • (2006) Mol Cell Proteomics , vol.5 , pp. 1131-1145
    • Hwang, S.-I.1    Lundgren, D.H.2    Mayya, V.3
  • 70
    • 77956543007 scopus 로고    scopus 로고
    • Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation
    • Moulder R, Lonnberg T, Elo LL et al. Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation. Mol Cell Proteomics 2010;9:1937-53.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1937-1953
    • Moulder, R.1    Lonnberg, T.2    Elo, L.L.3
  • 72
    • 84863339052 scopus 로고    scopus 로고
    • Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry
    • Orr SJ, Boutz DR, Wang R et al. Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry. Mol Syst Biol 2012;8:1-14.
    • (2012) Mol Syst Biol , vol.8 , pp. 1-14
    • Orr, S.J.1    Boutz, D.R.2    Wang, R.3
  • 73
    • 77952956167 scopus 로고    scopus 로고
    • Decoding signalling networks by mass spectrometry-based proteomics
    • Choudhary C, Mann M. Decoding signalling networks by mass spectrometry-based proteomics. Nat Rev Mol Cell Biol 2010;11:427-39.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 427-439
    • Choudhary, C.1    Mann, M.2
  • 74
    • 1842631103 scopus 로고    scopus 로고
    • Jurkat T cells and development of the T-cell receptor signalling paradigm
    • Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol 2004;4:301-8.
    • (2004) Nat Rev Immunol , vol.4 , pp. 301-308
    • Abraham, R.T.1    Weiss, A.2
  • 75
    • 0037458030 scopus 로고    scopus 로고
    • Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry
    • Salomon AR, Ficarro SB, Brill LM et al. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proc Natl Acad Sci USA 2003;100:443-8.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 443-448
    • Salomon, A.R.1    Ficarro, S.B.2    Brill, L.M.3
  • 76
    • 2442658049 scopus 로고    scopus 로고
    • Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry
    • Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Anal Chem 2004;76:2763-72.
    • (2004) Anal Chem , vol.76 , pp. 2763-2772
    • Brill, L.M.1    Salomon, A.R.2    Ficarro, S.B.3    Mukherji, M.4    Stettler-Gill, M.5    Peters, E.C.6
  • 77
    • 33644554807 scopus 로고    scopus 로고
    • Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells
    • Kim J-E, White FM. Quantitative analysis of phosphotyrosine signaling networks triggered by CD3 and CD28 costimulation in Jurkat cells. J Immunol 2006;176:2833-43.
    • (2006) J Immunol , vol.176 , pp. 2833-2843
    • Kim, J.-E.1    White, F.M.2
  • 78
    • 67651229135 scopus 로고    scopus 로고
    • Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways
    • Matsumoto M, Oyamada K, Takahashi H, Sato T, Hatakeyama S, Nakayama KI. Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways. Proteomics 2009;9:3549-63.
    • (2009) Proteomics , vol.9 , pp. 3549-3563
    • Matsumoto, M.1    Oyamada, K.2    Takahashi, H.3    Sato, T.4    Hatakeyama, S.5    Nakayama, K.I.6
  • 79
    • 70350462371 scopus 로고    scopus 로고
    • Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions
    • Mayya V, Lundgren DH, Hwang SI et al. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal 2009;2:ra46.
    • (2009) Sci Signal , vol.2
    • Mayya, V.1    Lundgren, D.H.2    Hwang, S.I.3
  • 80
    • 72149093283 scopus 로고    scopus 로고
    • A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation
    • Nguyen V, Cao L, Lin JT et al. A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Mol Cell Proteomics 2009;8:2418-31.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 2418-2431
    • Nguyen, V.1    Cao, L.2    Lin, J.T.3
  • 81
    • 79953202189 scopus 로고    scopus 로고
    • T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component
    • Brockmeyer C, Paster W, Pepper D et al. T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component. J Biol Chem 2011;286:7535-47.
    • (2011) J Biol Chem , vol.286 , pp. 7535-7547
    • Brockmeyer, C.1    Paster, W.2    Pepper, D.3
  • 82
    • 29244435791 scopus 로고    scopus 로고
    • B7/CD28 costimulation of T cells induces a distinct proteome pattern
    • Kronfeld K, Hochleitner E, Mendler S et al. B7/CD28 costimulation of T cells induces a distinct proteome pattern. Mol Cell Proteomics 2005;4:1876-87.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1876-1887
    • Kronfeld, K.1    Hochleitner, E.2    Mendler, S.3
  • 83
    • 61349179532 scopus 로고    scopus 로고
    • Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment
    • Carrascal M, Ovelleiro D, Casas V, Gay M, Abian J. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. J Proteome Res 2008;7:5167-76.
    • (2008) J Proteome Res , vol.7 , pp. 5167-5176
    • Carrascal, M.1    Ovelleiro, D.2    Casas, V.3    Gay, M.4    Abian, J.5
  • 84
    • 84861136348 scopus 로고    scopus 로고
    • Quantitative phosphoproteomic analysis reveals a role for serine and threonine kinases in the cytoskeletal reorganization in early T-cell receptor (TCR) activation in human primary T-cells
    • Ruperez P, Gago-Martinez A, Burlingame AL, Oses-Prieto JA. Quantitative phosphoproteomic analysis reveals a role for serine and threonine kinases in the cytoskeletal reorganization in early T-cell receptor (TCR) activation in human primary T-cells. Mol Cell Proteomics 2012;11:171-86.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 171-186
    • Ruperez, P.1    Gago-Martinez, A.2    Burlingame, A.L.3    Oses-Prieto, J.A.4
  • 86
    • 0033811659 scopus 로고    scopus 로고
    • Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
    • Shan X, Czar MJ, Bunnell SC et al. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol Cell Biol 2000;20:6945-57.
    • (2000) Mol Cell Biol , vol.20 , pp. 6945-6957
    • Shan, X.1    Czar, M.J.2    Bunnell, S.C.3
  • 87
    • 0035991823 scopus 로고    scopus 로고
    • The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells
    • Xu Z, Stokoe D, Kane LP, Weiss A. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells. Cell Growth Differ 2002;13:285-96.
    • (2002) Cell Growth Differ , vol.13 , pp. 285-296
    • Xu, Z.1    Stokoe, D.2    Kane, L.P.3    Weiss, A.4
  • 88
    • 65549139807 scopus 로고    scopus 로고
    • Comparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cells
    • Bartelt RR, Cruz-Orcutt N, Collins M, Houtman JCD. Comparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cells. PLoS ONE 2009;4:e5430.
    • (2009) PLoS ONE , vol.4
    • Bartelt, R.R.1    Cruz-Orcutt, N.2    Collins, M.3    Houtman, J.C.D.4
  • 89
    • 84858727761 scopus 로고    scopus 로고
    • Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics
    • Osinalde N, Moss H, Arrizabalaga O et al. Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics. J Proteomics 2011;75:177-91.
    • (2011) J Proteomics , vol.75 , pp. 177-191
    • Osinalde, N.1    Moss, H.2    Arrizabalaga, O.3
  • 90
  • 91
    • 4344629701 scopus 로고    scopus 로고
    • Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes
    • Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Mol Cell 2004;15:559-71.
    • (2004) Mol Cell , vol.15 , pp. 559-571
    • Mowen, K.A.1    Schurter, B.T.2    Fathman, J.W.3    David, M.4    Glimcher, L.H.5
  • 92
    • 84861023172 scopus 로고    scopus 로고
    • Somatic STAT3 mutations in large granular lymphocytic leukemia
    • Koskela HL, Eldfors S, Ellonen P et al. Somatic STAT3 mutations in large granular lymphocytic leukemia. N Engl J Med 2012;366:1905-13.
    • (2012) N Engl J Med , vol.366 , pp. 1905-1913
    • Koskela, H.L.1    Eldfors, S.2    Ellonen, P.3
  • 93
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen M, Uyttenhove C, van Snick J et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008;9:1341-6.
    • (2008) Nat Immunol , vol.9 , pp. 1341-1346
    • Veldhoen, M.1    Uyttenhove, C.2    van Snick, J.3
  • 94
    • 72849131815 scopus 로고    scopus 로고
    • Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
    • Eyerich S, Eyerich K, Pennino D et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest 2009;119:3573-85.
    • (2009) J Clin Invest , vol.119 , pp. 3573-3585
    • Eyerich, S.1    Eyerich, K.2    Pennino, D.3
  • 95
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva RI, Chung Y, Hwang D et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008;29:138-49.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3
  • 98
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011;29:621-63.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 100
    • 84867581744 scopus 로고    scopus 로고
    • A validated regulatory network for Th17 cell specification
    • Ciofani M, Madar A, Galan C et al. A validated regulatory network for Th17 cell specification. Cell 2012;151:289-303.
    • (2012) Cell , vol.151 , pp. 289-303
    • Ciofani, M.1    Madar, A.2    Galan, C.3


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