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Volumn 366, Issue 20, 2012, Pages 1905-1913

Somatic STAT3 mutations in large granular lymphocytic leukemia

(29)  Koskela, Hanna L M a   Eldfors, Samuli a   Ellonen, Pekka a   Van Adrichem, Arjan J a   Kuusanmäki, Heikki a   Andersson, Emma I a   Lagström, Sonja a   Clemente, Michael J e   Olson, Thomas f   Jalkanen, Sari E a   Majumder, Muntasir Mamun a   Almusa, Henrikki a   Edgren, Henrik a   Lepistö, Maija a   Mattila, Pirkko a,b   Guinta, Kathryn e   Koistinen, Pirjo c   Kuittinen, Taru d   Penttinen, Kati a   Parsons, Alun a   more..


Author keywords

[No Author keywords available]

Indexed keywords

STAT3 PROTEIN;

EID: 84861023172     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1114885     Document Type: Article
Times cited : (646)

References (35)
  • 1
    • 0021909118 scopus 로고
    • Leukemia of large granular lymphocytes: Association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia
    • Loughran TP Jr, Kadin ME, Starkebaum G, et al. Leukemia of large granular lymphocytes: association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia. Ann Intern Med 1985;102:169-75. (Pubitemid 15157163)
    • (1985) Annals of Internal Medicine , vol.102 , Issue.2 , pp. 169-175
    • Loughran Jr., T.P.1    Kadin, M.E.2    Starkebaum, G.3
  • 2
    • 0027300176 scopus 로고
    • Clonal diseases of large granular lymphocytes
    • Loughran TP Jr. Clonal diseases of large granular lymphocytes. Blood 1993;82:1-14.
    • (1993) Blood , vol.82 , pp. 1-14
    • Loughran Jr., T.P.1
  • 3
    • 33645056193 scopus 로고    scopus 로고
    • Large granular lymphocyte leukemia
    • Sokol L, Loughran TP Jr. Large granular lymphocyte leukemia. Oncologist 2006;11:263-73.
    • (2006) Oncologist , vol.11 , pp. 263-273
    • Sokol, L.1    Loughran Jr., T.P.2
  • 4
    • 33747044148 scopus 로고    scopus 로고
    • Pathogenesis of neutropenia in large granular lymphocyte leukemia and Felty syndrome
    • DOI 10.1016/j.blre.2006.01.003, PII S0268960X0600004X
    • Burks EJ, Loughran TP Jr. Pathogenesis of neutropenia in large granular lymphocyte leukemia and Felty syndrome. Blood Rev 2006;20:245-66. (Pubitemid 44209204)
    • (2006) Blood Reviews , vol.20 , Issue.5 , pp. 245-266
    • Burks, E.J.1    Loughran Jr., T.P.2
  • 8
    • 68749108104 scopus 로고    scopus 로고
    • Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
    • Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 2009;23:1398-405.
    • (2009) Leukemia , vol.23 , pp. 1398-1405
    • Mustjoki, S.1    Ekblom, M.2    Arstila, T.P.3
  • 9
    • 84855164715 scopus 로고    scopus 로고
    • Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia
    • Clemente MJ, Wlodarski MW, Makishima H, et al. Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia. Blood 2011;118:4384-93.
    • (2011) Blood , vol.118 , pp. 4384-4393
    • Clemente, M.J.1    Wlodarski, M.W.2    Makishima, H.3
  • 10
    • 55849100058 scopus 로고    scopus 로고
    • Network model of survival signaling in large granular lymphocyte leukemia
    • Zhang R, Shah MV, Yang J, et al. Network model of survival signaling in large granular lymphocyte leukemia. Proc Natl Acad Sci U S A 2008;105:16308-13.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 16308-16313
    • Zhang, R.1    Shah, M.V.2    Yang, J.3
  • 11
    • 50949132631 scopus 로고    scopus 로고
    • Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes
    • Shah MV, Zhang R, Irby R, et al. Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes. Blood 2008;112:770-81.
    • (2008) Blood , vol.112 , pp. 770-781
    • Shah, M.V.1    Zhang, R.2    Irby, R.3
  • 13
    • 33745058740 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis
    • DOI 10.1182/blood-2005-08-3076
    • Schade AE, Powers JJ, Wlodarski MW, Maciejewski JP. Phosphatidylinositol- 3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis. Blood 2006;107:4834-40. (Pubitemid 43882635)
    • (2006) Blood , vol.107 , Issue.12 , pp. 4834-4840
    • Schade, A.E.1    Powers, J.J.2    Wlodarski, M.W.3    Maciejewski, J.P.4
  • 14
    • 33751253427 scopus 로고    scopus 로고
    • Pathophysiology defined by altered signal transduction pathways: The role of JAK-STAT and PI3K signaling in leukemic large granular lymphocytes
    • Schade AE, Wlodarski MW, Maciejewski JP. Pathophysiology defined by altered signal transduction pathways: the role of JAK-STAT and PI3K signaling in leukemic large granular lymphocytes. Cell Cycle 2006;5:2571-4. (Pubitemid 44785798)
    • (2006) Cell Cycle , vol.5 , Issue.22 , pp. 2571-2574
    • Schade, A.E.1    Wlodarski, M.W.2    Maciejewski, J.P.3
  • 15
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • Ley TJ, Mardis ER, Ding L, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 2008;456:66-72.
    • (2008) Nature , vol.456 , pp. 66-72
    • Ley, T.J.1    Mardis, E.R.2    Ding, L.3
  • 16
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009;361:1058-66.
    • (2009) N Engl J Med , vol.361 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3
  • 17
    • 79959293462 scopus 로고    scopus 로고
    • BRAF mutations in hairy-cell leukemia
    • Tiacci E, Trifonov V, Schiavoni G, et al. BRAF mutations in hairy-cell leukemia. N Engl J Med 2011;364:2305-15.
    • (2011) N Engl J Med , vol.364 , pp. 2305-2315
    • Tiacci, E.1    Trifonov, V.2    Schiavoni, G.3
  • 18
    • 80054010617 scopus 로고    scopus 로고
    • Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
    • Papaemmanuil E, Cazzola M, Boultwood J, et al. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med 2011;365:1384-95.
    • (2011) N Engl J Med , vol.365 , pp. 1384-1395
    • Papaemmanuil, E.1    Cazzola, M.2    Boultwood, J.3
  • 19
    • 84855370035 scopus 로고    scopus 로고
    • SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
    • Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011;365:2497-506.
    • (2011) N Engl J Med , vol.365 , pp. 2497-2506
    • Wang, L.1    Lawrence, M.S.2    Wan, Y.3
  • 21
    • 79960346759 scopus 로고    scopus 로고
    • Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas
    • Pilati C, Amessou M, Bihl MP, et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J Exp Med 2011;208:1359-66.
    • (2011) J Exp Med , vol.208 , pp. 1359-1366
    • Pilati, C.1    Amessou, M.2    Bihl, M.P.3
  • 23
    • 0032499801 scopus 로고    scopus 로고
    • Three-dimensional structure of the Stat3beta homodimer bound to DNA
    • DOI 10.1038/28101
    • Becker S, Groner B, Müller CW. Three-dimensional structure of the Stat-3beta homodimer bound to DNA. Nature 1998;394:145-51. (Pubitemid 28325960)
    • (1998) Nature , vol.394 , Issue.6689 , pp. 145-151
    • Becker, S.1    Groner, B.2    Muller, C.W.3
  • 24
    • 0035136846 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
    • Epling-Burnette PK, Liu JH, Catlett- Falcone R, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest 2001;107:351-62.
    • (2001) J Clin Invest , vol.107 , pp. 351-362
    • Epling-Burnette, P.K.1    Liu, J.H.2    Catlett-Falcone, R.3
  • 25
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell- specific stat3-deficient mice
    • Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, Akira S. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 1998;161:4652-60. (Pubitemid 28492039)
    • (1998) Journal of Immunology , vol.161 , Issue.9 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 27
    • 0038541842 scopus 로고    scopus 로고
    • + large granular lymphocyte leukemia
    • Lamy T, Liu JH, Landowski TH, Dalton WS, Loughran TP Jr. Dysregulation of CD95/CD95 ligand-apoptotic pathway in CD3(+) large granular lymphocyte leukemia. Blood 1998;92:4771-7. (Pubitemid 29005880)
    • (1998) Blood , vol.92 , Issue.12 , pp. 4771-4777
    • Lamy, T.1    Liu, J.H.2    Landowski, T.H.3    Dalton, W.S.4    Loughran, T.P.5
  • 28
    • 38949114252 scopus 로고    scopus 로고
    • Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemia
    • DOI 10.1182/blood-2007-06-093823
    • Yang J, Epling-Burnette PK, Painter JS, et al. Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemia. Blood 2008;111:1610-6. (Pubitemid 351213452)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1610-1616
    • Yang, J.1    Epling-Burnette, P.K.2    Painter, J.S.3    Zou, J.4    Bai, F.5    Wei, S.6    Loughran Jr., T.P.7
  • 32
    • 65149086162 scopus 로고    scopus 로고
    • A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia
    • Chen X, Bai F, Sokol L, et al. A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia. Blood 2009;113:3226-34.
    • (2009) Blood , vol.113 , pp. 3226-3234
    • Chen, X.1    Bai, F.2    Sokol, L.3
  • 33
    • 0028799973 scopus 로고
    • Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids
    • Wang F, Sengupta TK, Zhong Z, Ivashkiv LB. Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids. J Exp Med 1995;182:1825-31.
    • (1995) J Exp Med , vol.182 , pp. 1825-1831
    • Wang, F.1    Sengupta, T.K.2    Zhong, Z.3    Ivashkiv, L.B.4
  • 34
    • 38149015405 scopus 로고    scopus 로고
    • Constitutive STAT3 activation in peripheral CD3(+) cells from patients with primary Sjögren's syndrome
    • Ramos HL, Valencia-Pacheco G, Alcocer-Varela J. Constitutive STAT3 activation in peripheral CD3(+) cells from patients with primary Sjögren's syndrome. Scand J Rheumatol 2008;37:35-9.
    • (2008) Scand J Rheumatol , vol.37 , pp. 35-39
    • Ramos, H.L.1    Valencia-Pacheco, G.2    Alcocer-Varela, J.3


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