-
1
-
-
34247169028
-
Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship
-
Kraemer K.H., Patronas N.J., Schiffmann R., Brooks B.P., Tamura D., DiGiovanna J.J. Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship. Neuroscience 2007, 145:1388-1396.
-
(2007)
Neuroscience
, vol.145
, pp. 1388-1396
-
-
Kraemer, K.H.1
Patronas, N.J.2
Schiffmann, R.3
Brooks, B.P.4
Tamura, D.5
DiGiovanna, J.J.6
-
2
-
-
33845914051
-
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
-
Niedernhofer L.J., Garinis G.A., Raams A., Lalai A.S., Robinson A.R., Appeldoorn E., Odijk H., Oostendorp R., Ahmad A., van Leeuwen W., Theil A.F., Vermeulen W., van der Horst G.T., Meinecke P., Kleijer W.J., Vijg J., Jaspers N.G., Hoeijmakers J.H. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis. Nature 2006, 444:1038-1043.
-
(2006)
Nature
, vol.444
, pp. 1038-1043
-
-
Niedernhofer, L.J.1
Garinis, G.A.2
Raams, A.3
Lalai, A.S.4
Robinson, A.R.5
Appeldoorn, E.6
Odijk, H.7
Oostendorp, R.8
Ahmad, A.9
van Leeuwen, W.10
Theil, A.F.11
Vermeulen, W.12
van der Horst, G.T.13
Meinecke, P.14
Kleijer, W.J.15
Vijg, J.16
Jaspers, N.G.17
Hoeijmakers, J.H.18
-
3
-
-
38049178545
-
Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects
-
Fousteri M., Mullenders L.H. Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects. Cell Res. 2008, 18:73-84.
-
(2008)
Cell Res.
, vol.18
, pp. 73-84
-
-
Fousteri, M.1
Mullenders, L.H.2
-
4
-
-
38049164275
-
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
-
Shuck S.C., Short E.A., Turchi J.J. Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology. Cell Res. 2008, 18:64-72.
-
(2008)
Cell Res.
, vol.18
, pp. 64-72
-
-
Shuck, S.C.1
Short, E.A.2
Turchi, J.J.3
-
5
-
-
26944448202
-
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome
-
Sarker A.H., Tsutakawa S.E., Kostek S., Ng C., Shin D.S., Peris M., Campeau E., Tainer J.A., Nogales E., Cooper P.K. Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome. Mol. Cell 2005, 20:187-198.
-
(2005)
Mol. Cell
, vol.20
, pp. 187-198
-
-
Sarker, A.H.1
Tsutakawa, S.E.2
Kostek, S.3
Ng, C.4
Shin, D.S.5
Peris, M.6
Campeau, E.7
Tainer, J.A.8
Nogales, E.9
Cooper, P.K.10
-
6
-
-
0034437623
-
Transcription-coupled repair of oxidative DNA damage in human cells: mechanisms and consequences
-
Tsutakawa S.E., Cooper P.K. Transcription-coupled repair of oxidative DNA damage in human cells: mechanisms and consequences. Cold Spring Harb. Symp. Quant. Biol. 2000, 65:201-215.
-
(2000)
Cold Spring Harb. Symp. Quant. Biol.
, vol.65
, pp. 201-215
-
-
Tsutakawa, S.E.1
Cooper, P.K.2
-
8
-
-
33751345828
-
UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair
-
Sugasawa K. UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair. J. Mol. Histol. 2006, 37:189-202.
-
(2006)
J. Mol. Histol.
, vol.37
, pp. 189-202
-
-
Sugasawa, K.1
-
9
-
-
0035374836
-
Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair
-
Araki M., Masutani C., Takemura M., Uchida A., Sugasawa K., Kondoh J., Ohkuma Y., Hanaoka F. Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair. J. Biol. Chem. 2001, 276:18665-18672.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18665-18672
-
-
Araki, M.1
Masutani, C.2
Takemura, M.3
Uchida, A.4
Sugasawa, K.5
Kondoh, J.6
Ohkuma, Y.7
Hanaoka, F.8
-
10
-
-
84873522076
-
Functional insights into the core-TFIIH from a comparative survey
-
Bedez F., Linard B., Brochet X., Ripp R., Thompson J.D., Moras D., Lecompte O., Poch O. Functional insights into the core-TFIIH from a comparative survey. Genomics 2013, 101:178-186.
-
(2013)
Genomics
, vol.101
, pp. 178-186
-
-
Bedez, F.1
Linard, B.2
Brochet, X.3
Ripp, R.4
Thompson, J.D.5
Moras, D.6
Lecompte, O.7
Poch, O.8
-
11
-
-
34247256517
-
XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients
-
Ito S., Kuraoka I., Chymkowitch P., Compe E., Takedachi A., Ishigami C., Coin F., Egly J.M., Tanaka K. XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients. Mol. Cell 2007, 26:231-243.
-
(2007)
Mol. Cell
, vol.26
, pp. 231-243
-
-
Ito, S.1
Kuraoka, I.2
Chymkowitch, P.3
Compe, E.4
Takedachi, A.5
Ishigami, C.6
Coin, F.7
Egly, J.M.8
Tanaka, K.9
-
12
-
-
0040435451
-
TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair
-
Winkler G.S., Araujo S.J., Fiedler U., Vermeulen W., Coin F., Egly J.M., Hoeijmakers J.H., Wood R.D., Timmers H.T., Weeda G. TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair. J. Biol. Chem. 2000, 275:4258-4266.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4258-4266
-
-
Winkler, G.S.1
Araujo, S.J.2
Fiedler, U.3
Vermeulen, W.4
Coin, F.5
Egly, J.M.6
Hoeijmakers, J.H.7
Wood, R.D.8
Timmers, H.T.9
Weeda, G.10
-
13
-
-
0035796455
-
Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair
-
Missura M., Buterin T., Hindges R., Hubscher U., Kasparkova J., Brabec V., Naegeli H. Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair. EMBO J. 2001, 20:3554-3564.
-
(2001)
EMBO J.
, vol.20
, pp. 3554-3564
-
-
Missura, M.1
Buterin, T.2
Hindges, R.3
Hubscher, U.4
Kasparkova, J.5
Brabec, V.6
Naegeli, H.7
-
14
-
-
0037013193
-
Xeroderma pigmentosum complementation group A protein (XPA) modulates RPA-DNA interactions via enhanced complex stability and inhibition of strand separation activity
-
Patrick S.M., Turchi J.J. Xeroderma pigmentosum complementation group A protein (XPA) modulates RPA-DNA interactions via enhanced complex stability and inhibition of strand separation activity. J. Biol. Chem. 2002, 277:16096-16101.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16096-16101
-
-
Patrick, S.M.1
Turchi, J.J.2
-
15
-
-
67349212889
-
Coordination of dual incision and repair synthesis in human nucleotide excision repair
-
Staresincic L., Fagbemi A.F., Enzlin J.H., Gourdin A.M., Wijgers N., Dunand-Sauthier I., Giglia-Mari G., Clarkson S.G., Vermeulen W., Scharer O.D. Coordination of dual incision and repair synthesis in human nucleotide excision repair. EMBO J. 2009, 28:1111-1120.
-
(2009)
EMBO J.
, vol.28
, pp. 1111-1120
-
-
Staresincic, L.1
Fagbemi, A.F.2
Enzlin, J.H.3
Gourdin, A.M.4
Wijgers, N.5
Dunand-Sauthier, I.6
Giglia-Mari, G.7
Clarkson, S.G.8
Vermeulen, W.9
Scharer, O.D.10
-
16
-
-
77649242633
-
Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells
-
Ogi T., Limsirichaikul S., Overmeer R.M., Volker M., Takenaka K., Cloney R., Nakazawa Y., Niimi A., Miki Y., Jaspers N.G., Mullenders L.H., Yamashita S., Fousteri M.I., Lehmann A.R. Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol. Cell 2010, 37:714-727.
-
(2010)
Mol. Cell
, vol.37
, pp. 714-727
-
-
Ogi, T.1
Limsirichaikul, S.2
Overmeer, R.M.3
Volker, M.4
Takenaka, K.5
Cloney, R.6
Nakazawa, Y.7
Niimi, A.8
Miki, Y.9
Jaspers, N.G.10
Mullenders, L.H.11
Yamashita, S.12
Fousteri, M.I.13
Lehmann, A.R.14
-
17
-
-
34447302016
-
Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner
-
Moser J., Kool H., Giakzidis I., Caldecott K., Mullenders L.H., Fousteri M.I. Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner. Mol. Cell 2007, 27:311-323.
-
(2007)
Mol. Cell
, vol.27
, pp. 311-323
-
-
Moser, J.1
Kool, H.2
Giakzidis, I.3
Caldecott, K.4
Mullenders, L.H.5
Fousteri, M.I.6
-
18
-
-
33746666589
-
When transcription and repair meet: a complex system
-
Laine J.P., Egly J.M. When transcription and repair meet: a complex system. Trends Genet. 2006, 22:430-436.
-
(2006)
Trends Genet.
, vol.22
, pp. 430-436
-
-
Laine, J.P.1
Egly, J.M.2
-
19
-
-
49949152164
-
Nucleotide excision repair deficient mouse models and neurological disease
-
Niedernhofer L.J. Nucleotide excision repair deficient mouse models and neurological disease. DNA repair 2008, 7:1180-1189.
-
(2008)
DNA repair
, vol.7
, pp. 1180-1189
-
-
Niedernhofer, L.J.1
-
20
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak H., Alafuzoff I., Arzberger T., Kretzschmar H., Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol. (Berl.) 2006, 112:389-404.
-
(2006)
Acta Neuropathol. (Berl.)
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
21
-
-
0034007822
-
Pathoanatomy of Parkinson's disease
-
Braak H., Braak E. Pathoanatomy of Parkinson's disease. J. Neurol. 2000, 247(Suppl. 2):II3-II10.
-
(2000)
J. Neurol.
, vol.247
, Issue.SUPPL. 2
-
-
Braak, H.1
Braak, E.2
-
22
-
-
0022343684
-
Selective sparing of a class of striatal neurons in Huntington's disease
-
Ferrante R.J., Kowall N.W., Beal M.F., Richardson E.P., Bird E.D., Martin J.B. Selective sparing of a class of striatal neurons in Huntington's disease. Science (New York, NY) 1985, 230:561-563.
-
(1985)
Science (New York, NY)
, vol.230
, pp. 561-563
-
-
Ferrante, R.J.1
Kowall, N.W.2
Beal, M.F.3
Richardson, E.P.4
Bird, E.D.5
Martin, J.B.6
-
23
-
-
0023740954
-
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
-
Hirsch E., Graybiel A.M., Agid Y.A. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 1988, 334:345-348.
-
(1988)
Nature
, vol.334
, pp. 345-348
-
-
Hirsch, E.1
Graybiel, A.M.2
Agid, Y.A.3
-
24
-
-
79952405292
-
Neuronal calcium homeostasis and dysregulation
-
Gleichmann M., Mattson M.P. Neuronal calcium homeostasis and dysregulation. Antioxid. Redox Signal. 2011, 14:1261-1273.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1261-1273
-
-
Gleichmann, M.1
Mattson, M.P.2
-
25
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin M.T., Beal M.F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006, 443:787-795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
26
-
-
79955949858
-
The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration
-
Yamamoto A., Simonsen A. The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration. Neurobiol. Dis. 2011, 43:17-28.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 17-28
-
-
Yamamoto, A.1
Simonsen, A.2
-
27
-
-
84867022857
-
Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats
-
Li J., Ma X., Yu W., Lou Z., Mu D., Wang Y., Shen B., Qi S. Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats. PLoS ONE 2012, 7:e46498.
-
(2012)
PLoS ONE
, vol.7
-
-
Li, J.1
Ma, X.2
Yu, W.3
Lou, Z.4
Mu, D.5
Wang, Y.6
Shen, B.7
Qi, S.8
-
28
-
-
84857508603
-
The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice
-
Niatsetskaya Z.V., Sosunov S.A., Matsiukevich D., Utkina-Sosunova I.V., Ratner V.I., Starkov A.A., Ten V.S. The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice. J. Neurosci. 2012, 32:3235-3244.
-
(2012)
J. Neurosci.
, vol.32
, pp. 3235-3244
-
-
Niatsetskaya, Z.V.1
Sosunov, S.A.2
Matsiukevich, D.3
Utkina-Sosunova, I.V.4
Ratner, V.I.5
Starkov, A.A.6
Ten, V.S.7
-
29
-
-
79954628624
-
NADPH oxidase is involved in post-ischemic brain inflammation
-
Chen H., Kim G.S., Okami N., Narasimhan P., Chan P.H. NADPH oxidase is involved in post-ischemic brain inflammation. Neurobiol. Dis. 2011, 42:341-348.
-
(2011)
Neurobiol. Dis.
, vol.42
, pp. 341-348
-
-
Chen, H.1
Kim, G.S.2
Okami, N.3
Narasimhan, P.4
Chan, P.H.5
-
30
-
-
84857642949
-
The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes
-
Benilova I., Karran E., De Strooper B. The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes. Nat. Neurosci. 2012, 15:349-357.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 349-357
-
-
Benilova, I.1
Karran, E.2
De Strooper, B.3
-
31
-
-
81855199724
-
The role of environmental exposures in neurodegeneration and neurodegenerative diseases
-
Cannon J.R., Greenamyre J.T. The role of environmental exposures in neurodegeneration and neurodegenerative diseases. Toxicol. Sci. 2011, 124:225-250.
-
(2011)
Toxicol. Sci.
, vol.124
, pp. 225-250
-
-
Cannon, J.R.1
Greenamyre, J.T.2
-
32
-
-
75949083202
-
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
-
Martinez A., Portero-Otin M., Pamplona R., Ferrer I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. Brain Pathol. 2010, 20:281-297.
-
(2010)
Brain Pathol.
, vol.20
, pp. 281-297
-
-
Martinez, A.1
Portero-Otin, M.2
Pamplona, R.3
Ferrer, I.4
-
33
-
-
84859842601
-
Regional susceptibilities to mitochondrial dysfunctions in the CNS
-
Pinto M., Pickrell A.M., Moraes C.T. Regional susceptibilities to mitochondrial dysfunctions in the CNS. Biol. Chem. 2012, 393:275-281.
-
(2012)
Biol. Chem.
, vol.393
, pp. 275-281
-
-
Pinto, M.1
Pickrell, A.M.2
Moraes, C.T.3
-
34
-
-
84860695796
-
PGC-1alpha at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond
-
Tsunemi T., La Spada A.R. PGC-1alpha at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond. Prog. Neurobiol. 2012, 97:142-151.
-
(2012)
Prog. Neurobiol.
, vol.97
, pp. 142-151
-
-
Tsunemi, T.1
La Spada, A.R.2
-
35
-
-
0021256895
-
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner G.G., Wong C.W. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 1984, 120:885-890.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
36
-
-
32444432146
-
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease
-
Guo J.P., Arai T., Miklossy J., McGeer P.L. Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:1953-1958.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 1953-1958
-
-
Guo, J.P.1
Arai, T.2
Miklossy, J.3
McGeer, P.L.4
-
37
-
-
0037072278
-
Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease
-
Delacourte A., Sergeant N., Champain D., Wattez A., Maurage C.A., Lebert F., Pasquier F., David J.P. Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease. Neurology 2002, 59:398-407.
-
(2002)
Neurology
, vol.59
, pp. 398-407
-
-
Delacourte, A.1
Sergeant, N.2
Champain, D.3
Wattez, A.4
Maurage, C.A.5
Lebert, F.6
Pasquier, F.7
David, J.P.8
-
38
-
-
0030957671
-
Alzheimer's disease: transiently developing dendritic changes in pyramidal cells of sector CA1 of the Ammon's horn
-
Braak E., Braak H. Alzheimer's disease: transiently developing dendritic changes in pyramidal cells of sector CA1 of the Ammon's horn. Acta Neuropathol. (Berl.) 1997, 93:323-325.
-
(1997)
Acta Neuropathol. (Berl.)
, vol.93
, pp. 323-325
-
-
Braak, E.1
Braak, H.2
-
39
-
-
0029013727
-
Staging of Alzheimer's disease-related neurofibrillary changes
-
Braak H., Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol. Aging 1995, 16:271-284.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 271-284
-
-
Braak, H.1
Braak, E.2
-
40
-
-
0030668423
-
Diagnostic criteria for neuropathologic assessment of Alzheimer's disease
-
Braak H., Braak E. Diagnostic criteria for neuropathologic assessment of Alzheimer's disease. Neurobiol. Aging 1997, 18:S85-S88.
-
(1997)
Neurobiol. Aging
, vol.18
-
-
Braak, H.1
Braak, E.2
-
42
-
-
72849115874
-
Neuropsychiatric symptoms in Parkinson's disease
-
Aarsland D., Marsh L., Schrag A. Neuropsychiatric symptoms in Parkinson's disease. Mov. Disord. 2009, 24:2175-2186.
-
(2009)
Mov. Disord.
, vol.24
, pp. 2175-2186
-
-
Aarsland, D.1
Marsh, L.2
Schrag, A.3
-
43
-
-
84855972240
-
Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts
-
Jellinger K.A. Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts. Mov. Disord. 2012, 27:8-30.
-
(2012)
Mov. Disord.
, vol.27
, pp. 8-30
-
-
Jellinger, K.A.1
-
44
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
-
Guzman J.N., Sanchez-Padilla J., Wokosin D., Kondapalli J., Ilijic E., Schumacker P.T., Surmeier D.J. Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature 2010, 468:696-700.
-
(2010)
Nature
, vol.468
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
Surmeier, D.J.7
-
45
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H., Del Tredici K., Rub U., de Vos R.A., Jansen Steur E.N., Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 2003, 24:197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
46
-
-
77958614199
-
Type 2 transglutaminase in Huntington's disease: a double-edged sword with clinical potential
-
Mastroberardino P.G., Piacentini M. Type 2 transglutaminase in Huntington's disease: a double-edged sword with clinical potential. J. Intern. Med. 2010, 268:419-431.
-
(2010)
J. Intern. Med.
, vol.268
, pp. 419-431
-
-
Mastroberardino, P.G.1
Piacentini, M.2
-
48
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M., Sapp E., Chase K.O., Davies S.W., Bates G.P., Vonsattel J.P., Aronin N. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science (New York, NY) 1997, 277:1990-1993.
-
(1997)
Science (New York, NY)
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
49
-
-
0036715380
-
'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease
-
Mastroberardino P.G., Iannicola C., Nardacci R., Bernassola F., De Laurenzi V., Melino G., Moreno S., Pavone F., Oliverio S., Fesus L., Piacentini M. 'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease. Cell Death Differ. 2002, 9:873-880.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 873-880
-
-
Mastroberardino, P.G.1
Iannicola, C.2
Nardacci, R.3
Bernassola, F.4
De Laurenzi, V.5
Melino, G.6
Moreno, S.7
Pavone, F.8
Oliverio, S.9
Fesus, L.10
Piacentini, M.11
-
50
-
-
0023227209
-
Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease
-
Ferrante R.J., Beal M.F., Kowall N.W., Richardson E.P., Martin J.B. Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease. Brain Res. 1987, 411:162-166.
-
(1987)
Brain Res.
, vol.411
, pp. 162-166
-
-
Ferrante, R.J.1
Beal, M.F.2
Kowall, N.W.3
Richardson, E.P.4
Martin, J.B.5
-
51
-
-
0035353742
-
Open interconnected model of basal ganglia-thalamocortical circuitry and its relevance to the clinical syndrome of Huntington's disease
-
Joel D. Open interconnected model of basal ganglia-thalamocortical circuitry and its relevance to the clinical syndrome of Huntington's disease. Mov. Disord. 2001, 16:407-423.
-
(2001)
Mov. Disord.
, vol.16
, pp. 407-423
-
-
Joel, D.1
-
52
-
-
34247156564
-
DNA repair, mitochondria, and neurodegeneration
-
Weissman L., de Souza-Pinto N.C., Stevnsner T., Bohr V.A. DNA repair, mitochondria, and neurodegeneration. Neuroscience 2007, 145:1318-1329.
-
(2007)
Neuroscience
, vol.145
, pp. 1318-1329
-
-
Weissman, L.1
de Souza-Pinto, N.C.2
Stevnsner, T.3
Bohr, V.A.4
-
53
-
-
24044438505
-
Transcription-coupled repair: a complex affair
-
Mellon I. Transcription-coupled repair: a complex affair. Mutat. Res. 2005, 577:155-161.
-
(2005)
Mutat. Res.
, vol.577
, pp. 155-161
-
-
Mellon, I.1
-
54
-
-
34247178359
-
DNA repair in differentiated cells: some new answers to old questions
-
Nouspikel T. DNA repair in differentiated cells: some new answers to old questions. Neuroscience 2007, 145:1213-1221.
-
(2007)
Neuroscience
, vol.145
, pp. 1213-1221
-
-
Nouspikel, T.1
-
55
-
-
84855288980
-
Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology
-
Jaarsma D., Van Der Pluijm I., De Waard M., Haasdijk E., Brandt R., Vermeij M., Rijksen Y., Maas A., Van Steeg H., Hoeijmakers J.H., van der Horst G.T. Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology. PLoS Genet. 2011, 7:e1002405.
-
(2011)
PLoS Genet.
, vol.7
-
-
Jaarsma, D.1
Van Der Pluijm, I.2
De Waard, M.3
Haasdijk, E.4
Brandt, R.5
Vermeij, M.6
Rijksen, Y.7
Maas, A.8
Van Steeg, H.9
Hoeijmakers, J.H.10
van der Horst, G.T.11
-
56
-
-
33846330887
-
Cockayne syndrome in adults: review with clinical and pathologic study of a new case
-
Rapin I., Weidenheim K., Lindenbaum Y., Rosenbaum P., Merchant S.N., Krishna S., Dickson D.W. Cockayne syndrome in adults: review with clinical and pathologic study of a new case. J. Child Neurol. 2006, 21:991-1006.
-
(2006)
J. Child Neurol.
, vol.21
, pp. 991-1006
-
-
Rapin, I.1
Weidenheim, K.2
Lindenbaum, Y.3
Rosenbaum, P.4
Merchant, S.N.5
Krishna, S.6
Dickson, D.W.7
-
57
-
-
37549033922
-
A neurological phenotype in mice with DNA repair gene Ercc1 deficiency
-
Lawrence N.J., Sacco J.J., Brownstein D.G., Gillingwater T.H., Melton D.W. A neurological phenotype in mice with DNA repair gene Ercc1 deficiency. DNA repair 2008, 7:281-291.
-
(2008)
DNA repair
, vol.7
, pp. 281-291
-
-
Lawrence, N.J.1
Sacco, J.J.2
Brownstein, D.G.3
Gillingwater, T.H.4
Melton, D.W.5
-
58
-
-
12644266319
-
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence
-
Weeda G., Donker I., de Wit J., Morreau H., Janssens R., Vissers C.J., Nigg A., van Steeg H., Bootsma D., Hoeijmakers J.H. Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence. Curr. Biol. 1997, 7:427-439.
-
(1997)
Curr. Biol.
, vol.7
, pp. 427-439
-
-
Weeda, G.1
Donker, I.2
de Wit, J.3
Morreau, H.4
Janssens, R.5
Vissers, C.J.6
Nigg, A.7
van Steeg, H.8
Bootsma, D.9
Hoeijmakers, J.H.10
-
59
-
-
80052359532
-
Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair
-
Borgesius N.Z., de Waard M.C., Van Der Pluijm I., Omrani A., Zondag G.C., van der Horst G.T., Melton D.W., Hoeijmakers J.H., Jaarsma D., Elgersma Y. Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair. J. Neurosci. 2011, 31:12543-12553.
-
(2011)
J. Neurosci.
, vol.31
, pp. 12543-12553
-
-
Borgesius, N.Z.1
de Waard, M.C.2
Van Der Pluijm, I.3
Omrani, A.4
Zondag, G.C.5
van der Horst, G.T.6
Melton, D.W.7
Hoeijmakers, J.H.8
Jaarsma, D.9
Elgersma, Y.10
-
60
-
-
33645520634
-
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
-
Jacobsen J.S., Wu C.C., Redwine J.M., Comery T.A., Arias R., Bowlby M., Martone R., Morrison J.H., Pangalos M.N., Reinhart P.H., Bloom F.E. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5161-5166.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 5161-5166
-
-
Jacobsen, J.S.1
Wu, C.C.2
Redwine, J.M.3
Comery, T.A.4
Arias, R.5
Bowlby, M.6
Martone, R.7
Morrison, J.H.8
Pangalos, M.N.9
Reinhart, P.H.10
Bloom, F.E.11
-
61
-
-
29244439038
-
Neural plasticity in the ageing brain
-
Burke S.N., Barnes C.A. Neural plasticity in the ageing brain. Nat. Rev. Neurosci. 2006, 7:30-40.
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 30-40
-
-
Burke, S.N.1
Barnes, C.A.2
-
63
-
-
79951499176
-
Glia: initiators and progressors of pathology in Parkinson's disease
-
Halliday G.M., Stevens C.H. Glia: initiators and progressors of pathology in Parkinson's disease. Mov. Disord. 2011, 26:6-17.
-
(2011)
Mov. Disord.
, vol.26
, pp. 6-17
-
-
Halliday, G.M.1
Stevens, C.H.2
-
64
-
-
84858704600
-
Glial cells in (patho)physiology
-
Parpura V., Heneka M.T., Montana V., Oliet S.H., Schousboe A., Haydon P.G., Stout R.F., Spray D.C., Reichenbach A., Pannicke T., Pekny M., Pekna M., Zorec R., Verkhratsky A. Glial cells in (patho)physiology. J. Neurochem. 2012, 121:4-27.
-
(2012)
J. Neurochem.
, vol.121
, pp. 4-27
-
-
Parpura, V.1
Heneka, M.T.2
Montana, V.3
Oliet, S.H.4
Schousboe, A.5
Haydon, P.G.6
Stout, R.F.7
Spray, D.C.8
Reichenbach, A.9
Pannicke, T.10
Pekny, M.11
Pekna, M.12
Zorec, R.13
Verkhratsky, A.14
-
65
-
-
84872168596
-
Microglia: scapegoat, saboteur, or something else?
-
Aguzzi A., Barres B.A., Bennett M.L. Microglia: scapegoat, saboteur, or something else?. Science 2013, 339:156-161.
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
66
-
-
84858306047
-
Antioxidant and bioenergetic coupling between neurons and astrocytes
-
Fernandez-Fernandez S., Almeida A., Bolanos J.P. Antioxidant and bioenergetic coupling between neurons and astrocytes. Biochem. J. 2012, 443:3-11.
-
(2012)
Biochem. J.
, vol.443
, pp. 3-11
-
-
Fernandez-Fernandez, S.1
Almeida, A.2
Bolanos, J.P.3
-
67
-
-
47249106950
-
Immunohistochemical analysis of nucleotide excision repair factors XPA and XPB in adult rat brain
-
(Hoboken, NJ: 2007)
-
Yang S.Z., Zhang Y.F., Zhang L.M., Huang Y.L., Sun F.Y. Immunohistochemical analysis of nucleotide excision repair factors XPA and XPB in adult rat brain. Anat. Rec. 2008, 291:775-780. (Hoboken, NJ: 2007).
-
(2008)
Anat. Rec.
, vol.291
, pp. 775-780
-
-
Yang, S.Z.1
Zhang, Y.F.2
Zhang, L.M.3
Huang, Y.L.4
Sun, F.Y.5
-
68
-
-
34047105287
-
Neurons and astrocytes exhibit lower activities of global genome nucleotide excision repair than do fibroblasts
-
Yamamoto A., Nakamura Y., Kobayashi N., Iwamoto T., Yoshioka A., Kuniyasu H., Kishimoto T., Mori T. Neurons and astrocytes exhibit lower activities of global genome nucleotide excision repair than do fibroblasts. DNA repair 2007, 6:649-657.
-
(2007)
DNA repair
, vol.6
, pp. 649-657
-
-
Yamamoto, A.1
Nakamura, Y.2
Kobayashi, N.3
Iwamoto, T.4
Yoshioka, A.5
Kuniyasu, H.6
Kishimoto, T.7
Mori, T.8
-
69
-
-
84862791997
-
Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice
-
Smith S.C., Robinson A.R., Niedernhofer L., Hetman M. Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice. Neurobiol. Dis. 2012, 45:1136-1144.
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 1136-1144
-
-
Smith, S.C.1
Robinson, A.R.2
Niedernhofer, L.3
Hetman, M.4
-
70
-
-
67349270965
-
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
-
Bu G. Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Nat. Rev. Neurosci. 2009, 10:333-344.
-
(2009)
Nat. Rev. Neurosci.
, vol.10
, pp. 333-344
-
-
Bu, G.1
-
71
-
-
84863510126
-
The link between altered cholesterol metabolism and Alzheimer's disease
-
Gamba P., Testa G., Sottero B., Gargiulo S., Poli G., Leonarduzzi G. The link between altered cholesterol metabolism and Alzheimer's disease. Ann. N.Y. Acad. Sci. 2012, 1259:54-64.
-
(2012)
Ann. N.Y. Acad. Sci.
, vol.1259
, pp. 54-64
-
-
Gamba, P.1
Testa, G.2
Sottero, B.3
Gargiulo, S.4
Poli, G.5
Leonarduzzi, G.6
-
72
-
-
73249128637
-
Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity
-
Usui K., Hulleman J.D., Paulsson J.F., Siegel S.J., Powers E.T., Kelly J.W. Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:18563-18568.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 18563-18568
-
-
Usui, K.1
Hulleman, J.D.2
Paulsson, J.F.3
Siegel, S.J.4
Powers, E.T.5
Kelly, J.W.6
-
73
-
-
80053928598
-
Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies
-
Shepardson N.E., Shankar G.M., Selkoe D.J. Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies. Arch. Neurol. 2011, 68:1239-1244.
-
(2011)
Arch. Neurol.
, vol.68
, pp. 1239-1244
-
-
Shepardson, N.E.1
Shankar, G.M.2
Selkoe, D.J.3
-
74
-
-
80051933340
-
Emerging roles for cholesterol in Huntington's disease
-
Valenza M., Cattaneo E. Emerging roles for cholesterol in Huntington's disease. Trends Neurosci. 2011, 34:474-486.
-
(2011)
Trends Neurosci.
, vol.34
, pp. 474-486
-
-
Valenza, M.1
Cattaneo, E.2
-
75
-
-
77956189163
-
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice
-
de Waard M.C., Van Der Pluijm I., Zuiderveen Borgesius N., Comley L.H., Haasdijk E., Rijksen Y., Ridwan Y., Zondag G., Hoeijmakers J.H., Elgersma Y., Gillingwater T.H., Jaarsma D. Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. Acta Neuropathol. (Berl.) 2010, 120:461-475.
-
(2010)
Acta Neuropathol. (Berl.)
, vol.120
, pp. 461-475
-
-
de Waard, M.C.1
Van Der Pluijm, I.2
Zuiderveen Borgesius, N.3
Comley, L.H.4
Haasdijk, E.5
Rijksen, Y.6
Ridwan, Y.7
Zondag, G.8
Hoeijmakers, J.H.9
Elgersma, Y.10
Gillingwater, T.H.11
Jaarsma, D.12
-
76
-
-
0028978672
-
High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC
-
Sands A.T., Abuin A., Sanchez A., Conti C.J., Bradley A. High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC. Nature 1995, 377:162-165.
-
(1995)
Nature
, vol.377
, pp. 162-165
-
-
Sands, A.T.1
Abuin, A.2
Sanchez, A.3
Conti, C.J.4
Bradley, A.5
-
77
-
-
0031049126
-
Characterization of defective nucleotide excision repair in XPC mutant mice
-
Cheo D.L., Ruven H.J., Meira L.B., Hammer R.E., Burns D.K., Tappe N.J., van Zeeland A.A., Mullenders L.H., Friedberg E.C. Characterization of defective nucleotide excision repair in XPC mutant mice. Mutat. Res. 1997, 374:1-9.
-
(1997)
Mutat. Res.
, vol.374
, pp. 1-9
-
-
Cheo, D.L.1
Ruven, H.J.2
Meira, L.B.3
Hammer, R.E.4
Burns, D.K.5
Tappe, N.J.6
van Zeeland, A.A.7
Mullenders, L.H.8
Friedberg, E.C.9
-
78
-
-
0029083409
-
Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA
-
de Vries A., van Oostrom C.T., Hofhuis F.M., Dortant P.M., Berg R.J., de Gruijl F.R., Wester P.W., van Kreijl C.F., Capel P.J., van Steeg H., Verbeek S.J. Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA. Nature 1995, 377:169-173.
-
(1995)
Nature
, vol.377
, pp. 169-173
-
-
de Vries, A.1
van Oostrom, C.T.2
Hofhuis, F.M.3
Dortant, P.M.4
Berg, R.J.5
de Gruijl, F.R.6
Wester, P.W.7
van Kreijl, C.F.8
Capel, P.J.9
van Steeg, H.10
Verbeek, S.J.11
-
79
-
-
0024334283
-
Mitochondrial function in Parkinson's disease
-
Bindoff L.A., Birch-Machin M., Cartlidge N.E., Parker W.D., Turnbull D.M. Mitochondrial function in Parkinson's disease. Lancet 1989, 2:49.
-
(1989)
Lancet
, vol.2
, pp. 49
-
-
Bindoff, L.A.1
Birch-Machin, M.2
Cartlidge, N.E.3
Parker, W.D.4
Turnbull, D.M.5
-
80
-
-
0029875381
-
Mitochondrial defect in Huntington's disease caudate nucleus
-
Gu M., Gash M.T., Mann V.M., Javoy-Agid F., Cooper J.M., Schapira A.H. Mitochondrial defect in Huntington's disease caudate nucleus. Ann. Neurol. 1996, 39:385-389.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 385-389
-
-
Gu, M.1
Gash, M.T.2
Mann, V.M.3
Javoy-Agid, F.4
Cooper, J.M.5
Schapira, A.H.6
-
81
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
Parker W.D., Boyson S.J., Parks J.K. Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann. Neurol. 1989, 26:719-723.
-
(1989)
Ann. Neurol.
, vol.26
, pp. 719-723
-
-
Parker, W.D.1
Boyson, S.J.2
Parks, J.K.3
-
82
-
-
0028201012
-
Reduced platelet cytochrome c oxidase activity in Alzheimer's disease
-
Parker W.D., Mahr N.J., Filley C.M., Parks J.K., Hughes D., Young D.A., Cullum C.M. Reduced platelet cytochrome c oxidase activity in Alzheimer's disease. Neurology 1994, 44:1086-1090.
-
(1994)
Neurology
, vol.44
, pp. 1086-1090
-
-
Parker, W.D.1
Mahr, N.J.2
Filley, C.M.3
Parks, J.K.4
Hughes, D.5
Young, D.A.6
Cullum, C.M.7
-
83
-
-
0028236018
-
Electron transport chain defects in Alzheimer's disease brain
-
Parker W.D., Parks J., Filley C.M., Kleinschmidt-DeMasters B.K. Electron transport chain defects in Alzheimer's disease brain. Neurology 1994, 44:1090-1096.
-
(1994)
Neurology
, vol.44
, pp. 1090-1096
-
-
Parker, W.D.1
Parks, J.2
Filley, C.M.3
Kleinschmidt-DeMasters, B.K.4
-
84
-
-
79954631595
-
Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults
-
Horowitz M.P., Milanese C., Di Maio R., Hu X., Montero L.M., Sanders L.H., Tapias V., Sepe S., van Cappellen W.A., Burton E.A., Greenamyre J.T., Mastroberardino P.G. Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults. Antioxid. Redox Signal. 2011, 15:855-871.
-
(2011)
Antioxid. Redox Signal.
, vol.15
, pp. 855-871
-
-
Horowitz, M.P.1
Milanese, C.2
Di Maio, R.3
Hu, X.4
Montero, L.M.5
Sanders, L.H.6
Tapias, V.7
Sepe, S.8
van Cappellen, W.A.9
Burton, E.A.10
Greenamyre, J.T.11
Mastroberardino, P.G.12
-
85
-
-
51349148325
-
A FRET-based method to study protein thiol oxidation in histological preparations
-
Mastroberardino P.G., Orr A.L., Hu X., Na H.M., Greenamyre J.T. A FRET-based method to study protein thiol oxidation in histological preparations. Free Radic. Biol. Med. 2008, 45:971-981.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 971-981
-
-
Mastroberardino, P.G.1
Orr, A.L.2
Hu, X.3
Na, H.M.4
Greenamyre, J.T.5
-
86
-
-
77953463398
-
Protein degradation, aggregation, and misfolding
-
Cuervo A.M., Wong E.S., Martinez-Vicente M. Protein degradation, aggregation, and misfolding. Mov. Disord. 2010, 25(Suppl. 1):S49-S54.
-
(2010)
Mov. Disord.
, vol.25
, Issue.SUPPL. 1
-
-
Cuervo, A.M.1
Wong, E.S.2
Martinez-Vicente, M.3
-
87
-
-
77957245642
-
Genetic mouse models of Parkinson's disease. The state of the art
-
Magen I., Chesselet M.F. Genetic mouse models of Parkinson's disease. The state of the art. Prog. Brain Res. 2010, 184:53-87.
-
(2010)
Prog. Brain Res.
, vol.184
, pp. 53-87
-
-
Magen, I.1
Chesselet, M.F.2
-
88
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science (New York, NY) 1996, 274:99-102.
-
(1996)
Science (New York, NY)
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
90
-
-
0032938295
-
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse
-
Wheeler V.C., Auerbach W., White J.K., Srinidhi J., Auerbach A., Ryan A., Duyao M.P., Vrbanac V., Weaver M., Gusella J.F., Joyner A.L., MacDonald M.E. Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse. Hum. Mol. Genet. 1999, 8:115-122.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 115-122
-
-
Wheeler, V.C.1
Auerbach, W.2
White, J.K.3
Srinidhi, J.4
Auerbach, A.5
Ryan, A.6
Duyao, M.P.7
Vrbanac, V.8
Weaver, M.9
Gusella, J.F.10
Joyner, A.L.11
MacDonald, M.E.12
-
91
-
-
0034163497
-
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
-
Wheeler V.C., White J.K., Gutekunst C.A., Vrbanac V., Weaver M., Li X.J., Li S.H., Yi H., Vonsattel J.P., Gusella J.F., Hersch S., Auerbach W., Joyner A.L., MacDonald M.E. Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice. Hum. Mol. Genet. 2000, 9:503-513.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 503-513
-
-
Wheeler, V.C.1
White, J.K.2
Gutekunst, C.A.3
Vrbanac, V.4
Weaver, M.5
Li, X.J.6
Li, S.H.7
Yi, H.8
Vonsattel, J.P.9
Gusella, J.F.10
Hersch, S.11
Auerbach, W.12
Joyner, A.L.13
MacDonald, M.E.14
-
92
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
-
Richfield E.K., Thiruchelvam M.J., Cory-Slechta D.A., Wuertzer C., Gainetdinov R.R., Caron M.G., Di Monte D., Federoff H.J. Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Exp. Neurol. 2002, 175:35-48.
-
(2002)
Exp. Neurol.
, vol.175
, pp. 35-48
-
-
Richfield, E.K.1
Thiruchelvam, M.J.2
Cory-Slechta, D.A.3
Wuertzer, C.4
Gainetdinov, R.R.5
Caron, M.G.6
Di Monte, D.7
Federoff, H.J.8
-
93
-
-
33847363531
-
Wild-type and mutant alpha-synuclein induce a multi-component gene expression profile consistent with shared pathophysiology in different transgenic mouse models of PD
-
Miller R.M., Kiser G.L., Kaysser-Kranich T., Casaceli C., Colla E., Lee M.K., Palaniappan C., Federoff H.J. Wild-type and mutant alpha-synuclein induce a multi-component gene expression profile consistent with shared pathophysiology in different transgenic mouse models of PD. Exp. Neurol. 2007, 204:421-432.
-
(2007)
Exp. Neurol.
, vol.204
, pp. 421-432
-
-
Miller, R.M.1
Kiser, G.L.2
Kaysser-Kranich, T.3
Casaceli, C.4
Colla, E.5
Lee, M.K.6
Palaniappan, C.7
Federoff, H.J.8
-
94
-
-
84866518216
-
An anatomically comprehensive atlas of the adult human brain transcriptome
-
Hawrylycz M.J., Lein E.S., Guillozet-Bongaarts A.L., Shen E.H., Ng L., Miller J.A., van de Lagemaat L.N., Smith K.A., Ebbert A., Riley Z.L., Abajian C., Beckmann C.F., Bernard A., Bertagnolli D., Boe A.F., Cartagena P.M., Chakravarty M.M., Chapin M., Chong J., Dalley R.A., Daly B.D., Dang C., Datta S., Dee N., Dolbeare T.A., Faber V., Feng D., Fowler D.R., Goldy J., Gregor B.W., Haradon Z., Haynor D.R., Hohmann J.G., Horvath S., Howard R.E., Jeromin A., Jochim J.M., Kinnunen M., Lau C., Lazarz E.T., Lee C., Lemon T.A., Li L., Li Y., Morris J.A., Overly C.C., Parker P.D., Parry S.E., Reding M., Royall J.J., Schulkin J., Sequeira P.A., Slaughterbeck C.R., Smith S.C., Sodt A.J., Sunkin S.M., Swanson B.E., Vawter M.P., Williams D., Wohnoutka P., Zielke H.R., Geschwind D.H., Hof P.R., Smith S.M., Koch C., Grant S.G., Jones A.R. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature 2012, 489:391-399.
-
(2012)
Nature
, vol.489
, pp. 391-399
-
-
Hawrylycz, M.J.1
Lein, E.S.2
Guillozet-Bongaarts, A.L.3
Shen, E.H.4
Ng, L.5
Miller, J.A.6
van de Lagemaat, L.N.7
Smith, K.A.8
Ebbert, A.9
Riley, Z.L.10
Abajian, C.11
Beckmann, C.F.12
Bernard, A.13
Bertagnolli, D.14
Boe, A.F.15
Cartagena, P.M.16
Chakravarty, M.M.17
Chapin, M.18
Chong, J.19
Dalley, R.A.20
Daly, B.D.21
Dang, C.22
Datta, S.23
Dee, N.24
Dolbeare, T.A.25
Faber, V.26
Feng, D.27
Fowler, D.R.28
Goldy, J.29
Gregor, B.W.30
Haradon, Z.31
Haynor, D.R.32
Hohmann, J.G.33
Horvath, S.34
Howard, R.E.35
Jeromin, A.36
Jochim, J.M.37
Kinnunen, M.38
Lau, C.39
Lazarz, E.T.40
Lee, C.41
Lemon, T.A.42
Li, L.43
Li, Y.44
Morris, J.A.45
Overly, C.C.46
Parker, P.D.47
Parry, S.E.48
Reding, M.49
Royall, J.J.50
Schulkin, J.51
Sequeira, P.A.52
Slaughterbeck, C.R.53
Smith, S.C.54
Sodt, A.J.55
Sunkin, S.M.56
Swanson, B.E.57
Vawter, M.P.58
Williams, D.59
Wohnoutka, P.60
Zielke, H.R.61
Geschwind, D.H.62
Hof, P.R.63
Smith, S.M.64
Koch, C.65
Grant, S.G.66
Jones, A.R.67
more..
-
95
-
-
0038339144
-
A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein
-
Ng J.M., Vermeulen W., van der Horst G.T., Bergink S., Sugasawa K., Vrieling H., Hoeijmakers J.H. A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein. Genes Dev. 2003, 17:1630-1645.
-
(2003)
Genes Dev.
, vol.17
, pp. 1630-1645
-
-
Ng, J.M.1
Vermeulen, W.2
van der Horst, G.T.3
Bergink, S.4
Sugasawa, K.5
Vrieling, H.6
Hoeijmakers, J.H.7
-
96
-
-
0036012784
-
UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice
-
van der Horst G.T., Meira L., Gorgels T.G., De Wit J., Velasco-Miguel S., Richardson J.A., Kamp Y., Vreeswijk M.P., Smit B., Bootsma D., Hoeijmakers J.H., Friedberg E.C. UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice. DNA Repair 2002, 1:143-157.
-
(2002)
DNA Repair
, vol.1
, pp. 143-157
-
-
van der Horst, G.T.1
Meira, L.2
Gorgels, T.G.3
De Wit, J.4
Velasco-Miguel, S.5
Richardson, J.A.6
Kamp, Y.7
Vreeswijk, M.P.8
Smit, B.9
Bootsma, D.10
Hoeijmakers, J.H.11
Friedberg, E.C.12
-
97
-
-
0030916337
-
Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition
-
van der Horst G.T., van Steeg H., Berg R.J., van Gool A.J., de Wit J., Weeda G., Morreau H., Beems R.B., van Kreijl C.F., de Gruijl F.R., Bootsma D., Hoeijmakers J.H. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 1997, 89:425-435.
-
(1997)
Cell
, vol.89
, pp. 425-435
-
-
van der Horst, G.T.1
van Steeg, H.2
Berg, R.J.3
van Gool, A.J.4
de Wit, J.5
Weeda, G.6
Morreau, H.7
Beems, R.B.8
van Kreijl, C.F.9
de Gruijl, F.R.10
Bootsma, D.11
Hoeijmakers, J.H.12
-
98
-
-
34147181052
-
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms
-
Melquist S., Craig D.W., Huentelman M.J., Crook R., Pearson J.V., Baker M., Zismann V.L., Gass J., Adamson J., Szelinger S., Corneveaux J., Cannon A., Coon K.D., Lincoln S., Adler C., Tuite P., Calne D.B., Bigio E.H., Uitti R.J., Wszolek Z.K., Golbe L.I., Caselli R.J., Graff-Radford N., Litvan I., Farrer M.J., Dickson D.W., Hutton M., Stephan D.A. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. Am. J. Hum. Genet. 2007, 80:769-778.
-
(2007)
Am. J. Hum. Genet.
, vol.80
, pp. 769-778
-
-
Melquist, S.1
Craig, D.W.2
Huentelman, M.J.3
Crook, R.4
Pearson, J.V.5
Baker, M.6
Zismann, V.L.7
Gass, J.8
Adamson, J.9
Szelinger, S.10
Corneveaux, J.11
Cannon, A.12
Coon, K.D.13
Lincoln, S.14
Adler, C.15
Tuite, P.16
Calne, D.B.17
Bigio, E.H.18
Uitti, R.J.19
Wszolek, Z.K.20
Golbe, L.I.21
Caselli, R.J.22
Graff-Radford, N.23
Litvan, I.24
Farrer, M.J.25
Dickson, D.W.26
Hutton, M.27
Stephan, D.A.28
more..
-
99
-
-
0029843707
-
Mutational analysis of the human nucleotide excision repair gene ERCC1
-
Sijbers A.M., van der Spek P.J., Odijk H., van den Berg J., van Duin M., Westerveld A., Jaspers N.G., Bootsma D., Hoeijmakers J.H. Mutational analysis of the human nucleotide excision repair gene ERCC1. Nucleic Acids Res. 1996, 24:3370-3380.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 3370-3380
-
-
Sijbers, A.M.1
van der Spek, P.J.2
Odijk, H.3
van den Berg, J.4
van Duin, M.5
Westerveld, A.6
Jaspers, N.G.7
Bootsma, D.8
Hoeijmakers, J.H.9
-
100
-
-
0036774538
-
DNA-polymerase alpha, beta, delta and epsilon activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex
-
Raji N.S., Krishna T.H., Rao K.S. DNA-polymerase alpha, beta, delta and epsilon activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex. Int. J. Dev. Neurosci. 2002, 20:491-496.
-
(2002)
Int. J. Dev. Neurosci.
, vol.20
, pp. 491-496
-
-
Raji, N.S.1
Krishna, T.H.2
Rao, K.S.3
-
101
-
-
79952368682
-
DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair
-
Gao Y., Katyal S., Lee Y., Zhao J., Rehg J.E., Russell H.R., McKinnon P.J. DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair. Nature 2011, 471:240-244.
-
(2011)
Nature
, vol.471
, pp. 240-244
-
-
Gao, Y.1
Katyal, S.2
Lee, Y.3
Zhao, J.4
Rehg, J.E.5
Russell, H.R.6
McKinnon, P.J.7
-
102
-
-
77953447144
-
A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease
-
Chan C.S., Gertler T.S., Surmeier D.J. A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease. Mov. Disord. 2010, 25(Suppl 1):S63-S70.
-
(2010)
Mov. Disord.
, vol.25
, Issue.SUPPL. 1
-
-
Chan, C.S.1
Gertler, T.S.2
Surmeier, D.J.3
-
103
-
-
84892680342
-
Higher iron in the red nucleus marks Parkinson's dyskinesia
-
Lewis M.M., Du G., Kidacki M., Patel N., Shaffer M.L., Mailman R.B., Huang X. Higher iron in the red nucleus marks Parkinson's dyskinesia. Neurobiol. Aging 2012.
-
(2012)
Neurobiol. Aging
-
-
Lewis, M.M.1
Du, G.2
Kidacki, M.3
Patel, N.4
Shaffer, M.L.5
Mailman, R.B.6
Huang, X.7
-
104
-
-
77953608905
-
Subthalamic and red nucleus volumes in patients with Parkinson's disease: do they change with disease progression?
-
Colpan M.E., Slavin K.V. Subthalamic and red nucleus volumes in patients with Parkinson's disease: do they change with disease progression?. Parkinsonism Relat. Disord. 2010, 16:398-403.
-
(2010)
Parkinsonism Relat. Disord.
, vol.16
, pp. 398-403
-
-
Colpan, M.E.1
Slavin, K.V.2
-
105
-
-
84862299730
-
Olfactory dysfunction in Parkinson disease
-
Doty R.L. Olfactory dysfunction in Parkinson disease. Nat. Rev. Neurol. 2012, 8:329-339.
-
(2012)
Nat. Rev. Neurol.
, vol.8
, pp. 329-339
-
-
Doty, R.L.1
-
106
-
-
74149094680
-
Brainstem pathology and non-motor symptoms in PD
-
Grinberg L.T., Rueb U., Alho A.T., Heinsen H. Brainstem pathology and non-motor symptoms in PD. J. Neurol. Sci. 2010, 289:81-88.
-
(2010)
J. Neurol. Sci.
, vol.289
, pp. 81-88
-
-
Grinberg, L.T.1
Rueb, U.2
Alho, A.T.3
Heinsen, H.4
|